EP2016066A4 - Process for preparing duloxetine - Google Patents

Process for preparing duloxetine

Info

Publication number
EP2016066A4
EP2016066A4 EP07762094A EP07762094A EP2016066A4 EP 2016066 A4 EP2016066 A4 EP 2016066A4 EP 07762094 A EP07762094 A EP 07762094A EP 07762094 A EP07762094 A EP 07762094A EP 2016066 A4 EP2016066 A4 EP 2016066A4
Authority
EP
European Patent Office
Prior art keywords
preparing duloxetine
duloxetine
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07762094A
Other languages
German (de)
French (fr)
Other versions
EP2016066A2 (en
Inventor
Srinivasalu Gudipati
Srinivas Katkam
Jaya Prakash Pitta
Prasad Ganji
Nageswara Rao Challa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Original Assignee
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Reddys Laboratories Ltd, Dr Reddys Laboratories Inc filed Critical Dr Reddys Laboratories Ltd
Publication of EP2016066A2 publication Critical patent/EP2016066A2/en
Publication of EP2016066A4 publication Critical patent/EP2016066A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
EP07762094A 2006-05-10 2007-05-10 Process for preparing duloxetine Withdrawn EP2016066A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN828CH2006 2006-05-10
US80525406P 2006-06-20 2006-06-20
US82063606P 2006-07-28 2006-07-28
PCT/US2007/068667 WO2007134168A2 (en) 2006-05-10 2007-05-10 Process for preparing duloxetine

Publications (2)

Publication Number Publication Date
EP2016066A2 EP2016066A2 (en) 2009-01-21
EP2016066A4 true EP2016066A4 (en) 2010-11-24

Family

ID=38694701

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07762094A Withdrawn EP2016066A4 (en) 2006-05-10 2007-05-10 Process for preparing duloxetine

Country Status (2)

Country Link
EP (1) EP2016066A4 (en)
WO (1) WO2007134168A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2107057A1 (en) 2008-04-04 2009-10-07 Ranbaxy Laboratories Limited Process for the preparation of pure duloxetine hydrochloride
EP2123626A1 (en) 2008-05-21 2009-11-25 Laboratorios del Dr. Esteve S.A. Co-crystals of duloxetine and co-crystal formers for the treatment of pain
EP2332930A1 (en) * 2009-11-23 2011-06-15 Laboratorios Del. Dr. Esteve, S.A. Salts of duloxetine and NSAIDs for the treatment of pain
WO2011077443A1 (en) * 2009-12-22 2011-06-30 Biocon Limited An improved process for the preparation of duloxetine hydrochloride
CN114778707A (en) * 2019-05-13 2022-07-22 南京制药厂有限公司 Method for determining duloxetine intermediate amide by liquid chromatography
CN113429380B (en) * 2021-07-14 2022-07-01 新发药业有限公司 Preparation method of duloxetine

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005108386A1 (en) * 2004-05-11 2005-11-17 Cipla Limited Crystalline forms of duloxetine free base
WO2006027798A2 (en) * 2004-08-05 2006-03-16 Sun Pharmaceutical Industries Limited A process for preparation of an antidepressant compound
WO2006045255A1 (en) * 2004-10-26 2006-05-04 Zentiva, A.S. Method of manufacturing (s)-n-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride (duloxetine)
WO2006071868A2 (en) * 2004-12-23 2006-07-06 Teva Pharmaceutical Industries Ltd. Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof
WO2007105021A2 (en) * 2006-03-13 2007-09-20 EGIS GYÓGYSZERGYÁR, Nyilvánosan Müködö Részvénytársaság Duloxetine salts
WO2007119116A2 (en) * 2005-12-12 2007-10-25 Medichem, S.A. Improved synthesis and preparations of duloxetine salts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362886A (en) * 1993-10-12 1994-11-08 Eli Lilly And Company Asymmetric synthesis
US5910319A (en) * 1997-05-29 1999-06-08 Eli Lilly And Company Fluoxetine enteric pellets and methods for their preparation and use
DE69905938T2 (en) * 1998-11-13 2003-11-13 Lilly Co Eli COMBINATION OF DULOXETIN WITH NON-STEROID INFLAMMATORY INHIBITORS FOR THE TREATMENT OF PAIN

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005108386A1 (en) * 2004-05-11 2005-11-17 Cipla Limited Crystalline forms of duloxetine free base
WO2006027798A2 (en) * 2004-08-05 2006-03-16 Sun Pharmaceutical Industries Limited A process for preparation of an antidepressant compound
WO2006045255A1 (en) * 2004-10-26 2006-05-04 Zentiva, A.S. Method of manufacturing (s)-n-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride (duloxetine)
WO2006071868A2 (en) * 2004-12-23 2006-07-06 Teva Pharmaceutical Industries Ltd. Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof
WO2007119116A2 (en) * 2005-12-12 2007-10-25 Medichem, S.A. Improved synthesis and preparations of duloxetine salts
WO2007105021A2 (en) * 2006-03-13 2007-09-20 EGIS GYÓGYSZERGYÁR, Nyilvánosan Müködö Részvénytársaság Duloxetine salts

Also Published As

Publication number Publication date
EP2016066A2 (en) 2009-01-21
WO2007134168A3 (en) 2008-01-24
WO2007134168A2 (en) 2007-11-22

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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AX Request for extension of the european patent

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DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20101026

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Effective date: 20110526