EP1581637A4 - Human stem cell materials and methods - Google Patents

Human stem cell materials and methods

Info

Publication number
EP1581637A4
EP1581637A4 EP03781813A EP03781813A EP1581637A4 EP 1581637 A4 EP1581637 A4 EP 1581637A4 EP 03781813 A EP03781813 A EP 03781813A EP 03781813 A EP03781813 A EP 03781813A EP 1581637 A4 EP1581637 A4 EP 1581637A4
Authority
EP
European Patent Office
Prior art keywords
methods
stem cell
human stem
cell materials
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03781813A
Other languages
German (de)
French (fr)
Other versions
EP1581637A2 (en
Inventor
Eliezer Huberman
Yong Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Chicago
Original Assignee
University of Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Chicago filed Critical University of Chicago
Priority to EP11152200A priority Critical patent/EP2357223A3/en
Publication of EP1581637A2 publication Critical patent/EP1581637A2/en
Publication of EP1581637A4 publication Critical patent/EP1581637A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2306—Interleukin-6 (IL-6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
EP03781813A 2002-11-07 2003-11-07 Human stem cell materials and methods Withdrawn EP1581637A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11152200A EP2357223A3 (en) 2002-11-07 2003-11-07 Human stem cell material and methods

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42444202P 2002-11-07 2002-11-07
US424442P 2002-11-07
PCT/US2003/035538 WO2004043990A2 (en) 2002-11-07 2003-11-07 Human stem cell materials and methods

Publications (2)

Publication Number Publication Date
EP1581637A2 EP1581637A2 (en) 2005-10-05
EP1581637A4 true EP1581637A4 (en) 2007-04-25

Family

ID=32312808

Family Applications (2)

Application Number Title Priority Date Filing Date
EP03781813A Withdrawn EP1581637A4 (en) 2002-11-07 2003-11-07 Human stem cell materials and methods
EP11152200A Withdrawn EP2357223A3 (en) 2002-11-07 2003-11-07 Human stem cell material and methods

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP11152200A Withdrawn EP2357223A3 (en) 2002-11-07 2003-11-07 Human stem cell material and methods

Country Status (4)

Country Link
EP (2) EP1581637A4 (en)
JP (1) JP2006512060A (en)
CA (1) CA2505394C (en)
WO (1) WO2004043990A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI288779B (en) 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
JP3762975B2 (en) * 2003-03-18 2006-04-05 学校法人慶應義塾 Monocyte-derived pluripotent cells MOMC
US20050260158A1 (en) * 2003-11-07 2005-11-24 Eliezer Huberman Human stem cell materials and methods
EP1600500A1 (en) * 2004-05-27 2005-11-30 Georg-August-Universität Göttingen Method for producing pluripotent cells from monocytes
AU2006202318A1 (en) * 2005-06-02 2006-12-21 Wing-Yee Chan The preparation of multipotent stem cells and the use thereof
US9155762B2 (en) 2005-12-08 2015-10-13 University Of Louisville Research Foundation, Inc. Uses and isolation of stem cells from bone marrow
US20090220466A1 (en) * 2005-12-08 2009-09-03 Mariusz Ratajczak Very small embryonic-like (vsel) stem cells and methods of isolating and using the same
ITRM20060498A1 (en) 2006-09-20 2008-03-21 Alessandra Gambacurta METHOD OF EXPANSION OF ADULT STEM CELLS FROM PERIPHERAL BLOOD AND RELATED USES IN MEDICAL FIELD
ITUD20080058A1 (en) 2008-03-18 2009-09-19 Thankstem S R L PREFERIBLY PERIPHERAL BLOOD COLLECTION KIT, FOR THE PRODUCTION OF STEM CELLS
US10271876B2 (en) 2011-11-23 2019-04-30 Mezadata Medical Ip Holding Llc Method of in vitro fertilization with delay of embryo transfer and use of peripheral blood mononuclear cells
AR101442A1 (en) 2014-05-09 2016-12-21 Thankstem S R L METHOD FOR THE EXPANSION OF BLOOD MOTHER CELLS
US11312940B2 (en) 2015-08-31 2022-04-26 University Of Louisville Research Foundation, Inc. Progenitor cells and methods for preparing and using the same
EP3423568A4 (en) 2016-03-04 2019-11-13 University Of Louisville Research Foundation, Inc. Methods and compositions for ex vivo expansion of very small embryonic-like stem cells (vsels)
CN111808800B (en) * 2020-07-20 2022-08-26 中南大学湘雅二医院 In-vitro induced immunosuppressive myeloid suppressor cell and preparation and application thereof
CN113667637B (en) * 2021-08-05 2023-06-16 大连医科大学 Method for in vitro induction of differentiation and amplification of human peripheral MDSCs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020001826A1 (en) * 1999-12-22 2002-01-03 Wager Ruth E. Hematopoietic cells and methods based thereon
DE10214095C1 (en) * 2002-03-28 2003-09-25 Bernd Karl Friedrich Kremer Producing dedifferentiated, programmable stem cells of human monocytic origin using culture medium having M-CSF and IL-3, useful in treating cirrhosis, pancreatic insufficiency, kidney failure, cardiac infarction and stroke
WO2003083092A1 (en) * 2002-03-28 2003-10-09 Blasticon Biotechnologische Forschung Gmbh Dedifferentiated, programmable stem cells of monocytic origin, and their production and use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US424442A (en) 1890-03-25 Chusetts
US6534055B1 (en) * 1988-11-23 2003-03-18 Genetics Institute, Inc. Methods for selectively stimulating proliferation of T cells
US5409825A (en) * 1991-04-09 1995-04-25 Indiana University Foundation Expansion of human hematopoietic progenitor cells in a liquid medium
WO1993012805A1 (en) * 1992-01-02 1993-07-08 Regents Of The University Of Michigan Methods for regulatory lineages of human hematopoietic cells
US5733541A (en) * 1995-04-21 1998-03-31 The Regent Of The University Of Michigan Hematopoietic cells: compositions and methods
WO1999020740A2 (en) * 1997-10-23 1999-04-29 Geron Corporation Methods and materials for the growth of primate-derived primordial stem cells
EP2058389B1 (en) * 1997-10-27 2016-05-18 Rockefeller University Defined dendritic cell maturation medium comprising TNF-alpha, IL-1beta, IL-6
US6586192B1 (en) * 1998-05-29 2003-07-01 Thomas Jefferson University Compositions and methods for use in affecting hematopoietic stem cell populations in mammals
ES2293912T3 (en) * 1999-06-29 2008-04-01 The Board Of Trustees Of The Leland Stanford Junior University SUBGROUPS OF MELIFEROUS MYELOID PROGENITOR CELLS.
ES2302726T3 (en) * 2000-02-24 2008-08-01 Invitrogen Corporation STIMULATION AND SIMULTANEOUS CONCENTRATION OF CELLS.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020001826A1 (en) * 1999-12-22 2002-01-03 Wager Ruth E. Hematopoietic cells and methods based thereon
DE10214095C1 (en) * 2002-03-28 2003-09-25 Bernd Karl Friedrich Kremer Producing dedifferentiated, programmable stem cells of human monocytic origin using culture medium having M-CSF and IL-3, useful in treating cirrhosis, pancreatic insufficiency, kidney failure, cardiac infarction and stroke
WO2003083092A1 (en) * 2002-03-28 2003-10-09 Blasticon Biotechnologische Forschung Gmbh Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
EP1506999A1 (en) * 2002-03-28 2005-02-16 Blasticon Biotechnologische Forschung GmbH Dedifferentiated, programmable stem cells of monocytic origin, and their production and use

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BYKOVSKAIA S.N. ET AL.: "Differentiation of immunostimulatory stem-cell- and monocyte-derived dendritic cells involves maturation of intracellular compartments responsible for antigen presentation and secretion", STEM CELLS, vol. 20, September 2002 (2002-09-01) - September 2002 (2002-09-01), pages 380 - 393, XP002423999 *
CLAUSENJ. ET AL.: "Blood-derived macrophage layers in the presence of hydrocortisone support myeloid progenitors in long-term cultures of CD34+ cord blood and bone marrow cells", ANNUAL HEMATOLOGY, vol. 79, February 2000 (2000-02-01) - February 2000 (2000-02-01), pages 59 - 65, XP002423998 *
ZHAO YONG ET AL: "A human peripheral blood monocyte-derived subset acts as pluripotent stem cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 100, no. 5, 4 March 2003 (2003-03-04), pages 2426 - 2431, XP002410596, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
JP2006512060A (en) 2006-04-13
CA2505394A1 (en) 2004-05-27
EP2357223A2 (en) 2011-08-17
EP2357223A3 (en) 2012-11-07
WO2004043990A2 (en) 2004-05-27
WO2004043990A3 (en) 2005-02-03
CA2505394C (en) 2014-05-13
EP1581637A2 (en) 2005-10-05

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