EP1578365A4 - Molecular interactions in neurons - Google Patents

Molecular interactions in neurons

Info

Publication number
EP1578365A4
EP1578365A4 EP03768964A EP03768964A EP1578365A4 EP 1578365 A4 EP1578365 A4 EP 1578365A4 EP 03768964 A EP03768964 A EP 03768964A EP 03768964 A EP03768964 A EP 03768964A EP 1578365 A4 EP1578365 A4 EP 1578365A4
Authority
EP
European Patent Office
Prior art keywords
neurons
molecular interactions
interactions
molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03768964A
Other languages
German (de)
French (fr)
Other versions
EP1578365A2 (en
Inventor
Peter S Lu
Jonathan David Garman
Michael P Belmares
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arbor Vita Corp
Original Assignee
Arbor Vita Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arbor Vita Corp filed Critical Arbor Vita Corp
Publication of EP1578365A2 publication Critical patent/EP1578365A2/en
Publication of EP1578365A4 publication Critical patent/EP1578365A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP03768964A 2002-11-14 2003-11-14 Molecular interactions in neurons Withdrawn EP1578365A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42621202P 2002-11-14 2002-11-14
US42621302P 2002-11-14 2002-11-14
US426212P 2002-11-14
US426213P 2002-11-14
PCT/US2003/036698 WO2004045535A2 (en) 2002-11-14 2003-11-14 Molecular interactions in neurons

Publications (2)

Publication Number Publication Date
EP1578365A2 EP1578365A2 (en) 2005-09-28
EP1578365A4 true EP1578365A4 (en) 2009-09-23

Family

ID=32329101

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03768964A Withdrawn EP1578365A4 (en) 2002-11-14 2003-11-14 Molecular interactions in neurons

Country Status (3)

Country Link
EP (1) EP1578365A4 (en)
CA (1) CA2505479A1 (en)
WO (1) WO2004045535A2 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6942981B1 (en) 1999-05-14 2005-09-13 Arbor Vita Corporation Method of determining interactions with PDZ-domain polypeptides
US20040082509A1 (en) 1999-10-12 2004-04-29 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US8183339B1 (en) 1999-10-12 2012-05-22 Xigen S.A. Cell-permeable peptide inhibitors of the JNK signal transduction pathway
DE10254601A1 (en) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Gene products differentially expressed in tumors and their use
EP1709084A4 (en) * 2003-12-23 2008-05-28 Nono Inc Polypeptides for modulating binding of trp channel proteins and trp-associated proteins
DE102004024617A1 (en) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentially expressed in tumors gene products and their use
WO2007002395A1 (en) * 2005-06-23 2007-01-04 Arbor Vita Corporation Methods and compositions for modulating cox
US8080517B2 (en) 2005-09-12 2011-12-20 Xigen Sa Cell-permeable peptide inhibitors of the JNK signal transduction pathway
WO2007031098A1 (en) 2005-09-12 2007-03-22 Xigen S.A. Cell-permeable peptide inhibitors of the jnk signal transduction pathway
EP1790664A1 (en) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
US8633160B2 (en) * 2005-12-30 2014-01-21 Nono Inc. Small molecule inhibitors of PDZ interactions
EP2043671B1 (en) * 2006-07-11 2020-05-20 NoNO Inc. Peptide and composition thereof for use in treating stroke with fever
EP1884521A1 (en) * 2006-07-31 2008-02-06 Xigen S.A. Fusion peptide for inhibiting interaction of neuronal NMDA receptor (NMDAR) and NMDAR interacting proteins
US8008253B2 (en) 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
WO2009143864A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases
WO2009143865A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2010072228A1 (en) 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
DK2440231T3 (en) * 2009-06-10 2020-01-13 Nono Inc CO-ADMINISTRATION OF AN AGENT BONDED TO A TAT INTERNALIZATION PERIOD WITH A MAST CELL DEGREANATION INHIBITOR
PT2440230T (en) * 2009-06-10 2021-02-03 Nono Inc Model systems and treatment regimes for treatment of neurological disease
WO2011160653A1 (en) 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
AU2010362444B2 (en) 2010-10-14 2015-08-06 Xigen Inflammation Ltd. Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
EP2581384A1 (en) 2011-10-11 2013-04-17 Institut Pasteur Products useful for the treatment of malignant neoplasms of the human nervous system
WO2013091670A1 (en) 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
WO2013167153A1 (en) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
CN106554386A (en) * 2015-09-25 2017-04-05 广州恒上医药技术有限公司 The epitope peptide of human papillomavirus and its application
CN111712252A (en) 2017-12-13 2020-09-25 纽约州立大学研究基金会 Peptides and other agents for treating pain and increasing pain sensitivity
CA3089649A1 (en) * 2018-03-08 2019-09-12 Phanes Therapeutics, Inc. Anti-tip-1 antibodies and uses thereof
CN114807142B (en) * 2022-05-26 2024-03-29 源生生物科技(青岛)有限责任公司 Annular RNA-circ-Magi1 and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2273622A1 (en) * 1999-06-02 2000-12-02 Michael Tymianski Inhibition of nmda receptor signalling in reducing neuronal damage
WO2002007751A1 (en) * 2000-07-25 2002-01-31 Axcell Biosciences Corporation Identification and isolation of novel polypeptides having pdz domains and methods of using same
WO2002057413A2 (en) * 2001-01-18 2002-07-25 The Board Of Trustees Of The Leland Stanford Junior University Peptides for activation and inhibition of delta pkc
WO2002090981A1 (en) * 2001-05-08 2002-11-14 Japan Science And Technology Corporation Antitumor antigen against htlv-1 tumor or antigen epitope thereof
WO2003014303A2 (en) * 2001-08-03 2003-02-20 Arbor Vita Corporation Molecular interactions in cells

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2273622A1 (en) * 1999-06-02 2000-12-02 Michael Tymianski Inhibition of nmda receptor signalling in reducing neuronal damage
WO2002007751A1 (en) * 2000-07-25 2002-01-31 Axcell Biosciences Corporation Identification and isolation of novel polypeptides having pdz domains and methods of using same
WO2002057413A2 (en) * 2001-01-18 2002-07-25 The Board Of Trustees Of The Leland Stanford Junior University Peptides for activation and inhibition of delta pkc
WO2002090981A1 (en) * 2001-05-08 2002-11-14 Japan Science And Technology Corporation Antitumor antigen against htlv-1 tumor or antigen epitope thereof
EP1391729A1 (en) * 2001-05-08 2004-02-25 Japan Science and Technology Corporation Antitumor antigen against htlv-1 tumor or antigen epitope thereof
WO2003014303A2 (en) * 2001-08-03 2003-02-20 Arbor Vita Corporation Molecular interactions in cells

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AARTS MICHELLE ET AL: "Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, WASHINGTON, DC, vol. 298, no. 5594, 25 October 2002 (2002-10-25), pages 846 - 850, XP002456870, ISSN: 0036-8075 *
KORNAU H-C ET AL: "Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, WASHINGTON, DC, vol. 269, no. 5231, 1 September 1995 (1995-09-01), pages 1737 - 1740, XP002196675, ISSN: 0036-8075 *
LIM I A ET AL: "Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM, US, vol. 277, no. 24, 14 June 2002 (2002-06-14), pages 21697 - 21698, XP002991766, ISSN: 0021-9258 *
ROUSSET R ET AL: "THE C-TERMINUS OF THE HTLV-1 TAX ONCOPROTEIN MEDIATES INTERACTION WITH THE PDZ DOMAIN OF CELLULAR PROTEINS", ONCOGENE, NATURE PUBLISHING GROUP, GB BASINGSTOKE, HANTS, vol. 16, no. 5, 5 February 1998 (1998-02-05), pages 643 - 654, XP000865909, ISSN: 0950-9232 *

Also Published As

Publication number Publication date
EP1578365A2 (en) 2005-09-28
CA2505479A1 (en) 2004-06-03
WO2004045535A3 (en) 2006-07-13
WO2004045535A2 (en) 2004-06-03

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