EP1221971A2 - Use of the combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines - Google Patents
Use of the combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccinesInfo
- Publication number
- EP1221971A2 EP1221971A2 EP00969296A EP00969296A EP1221971A2 EP 1221971 A2 EP1221971 A2 EP 1221971A2 EP 00969296 A EP00969296 A EP 00969296A EP 00969296 A EP00969296 A EP 00969296A EP 1221971 A2 EP1221971 A2 EP 1221971A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- vaccine
- antigen
- virus
- polyoxyethylene sorbitan
- influenza
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- AIDS & HIV (AREA)
- Otolaryngology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9922703.5A GB9922703D0 (en) | 1999-09-24 | 1999-09-24 | Vaccine |
GB9922703 | 1999-09-24 | ||
GB0016685 | 2000-07-06 | ||
GB0016685A GB0016685D0 (en) | 2000-07-06 | 2000-07-06 | Novel compounds |
PCT/EP2000/009366 WO2001021207A2 (en) | 1999-09-24 | 2000-09-22 | Use of combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1221971A2 true EP1221971A2 (en) | 2002-07-17 |
Family
ID=26244613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00969296A Withdrawn EP1221971A2 (en) | 1999-09-24 | 2000-09-22 | Use of the combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1221971A2 (en) |
JP (1) | JP2003509473A (en) |
KR (1) | KR20020038770A (en) |
CN (1) | CN1391483A (en) |
AU (1) | AU765824B2 (en) |
BR (1) | BR0014282A (en) |
CA (1) | CA2383413A1 (en) |
CO (1) | CO5200837A1 (en) |
CZ (1) | CZ20021043A3 (en) |
HK (1) | HK1049106A1 (en) |
HU (1) | HUP0202885A3 (en) |
IL (1) | IL148672A0 (en) |
MX (1) | MXPA02003067A (en) |
NO (1) | NO20021433L (en) |
PL (1) | PL355163A1 (en) |
TR (1) | TR200200774T2 (en) |
WO (1) | WO2001021207A2 (en) |
Families Citing this family (148)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2283012T3 (en) | 1996-01-04 | 2007-10-16 | Novartis Vaccines And Diagnostics, Inc. | HELICOBACTER PYLORI BACTERIOFERRITINE. |
MXPA03003690A (en) | 2000-10-27 | 2004-05-05 | Chiron Spa | Nucleic acids and proteins from streptococcus groups a b. |
WO2002046477A2 (en) | 2000-12-07 | 2002-06-13 | Chiron Corporation | Endogenous retroviruses up-regulated in prostate cancer |
MY134424A (en) * | 2001-05-30 | 2007-12-31 | Saechsisches Serumwerk | Stable influenza virus preparations with low or no amount of thiomersal |
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
US8481043B2 (en) | 2001-06-22 | 2013-07-09 | Cpex Pharmaceuticals, Inc. | Nasal immunization |
GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
AR045702A1 (en) | 2001-10-03 | 2005-11-09 | Chiron Corp | COMPOSITIONS OF ASSISTANTS. |
EP2572707A3 (en) | 2002-02-20 | 2013-11-06 | Novartis Vaccines and Diagnostics, Inc. | Microparticles with adsorbed polypeptide-containing molecules |
EP1532161B1 (en) | 2002-06-13 | 2012-02-15 | Novartis Vaccines and Diagnostics, Inc. | Vectors for expression of hml-2 polypeptides |
GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
ES2608048T3 (en) | 2002-10-11 | 2017-04-05 | Glaxosmithkline Biologicals Sa | Polypeptide vaccines for broad protection against hypervirulent meningococcal lineages |
US20070059329A1 (en) | 2002-11-15 | 2007-03-15 | Nathalie Norais | Unexpected surface proteins in meningococcus |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
WO2004060396A2 (en) | 2002-12-27 | 2004-07-22 | Chiron Corporation | Immunogenic compositions containing phospholpid |
CA2514328C (en) | 2003-01-30 | 2020-01-14 | Chiron Srl | Injectable vaccines against multiple meningococcal serogroups |
GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
US20060257852A1 (en) | 2003-04-10 | 2006-11-16 | Chiron Corporation | Severe acute respiratory syndrome coronavirus |
WO2005020964A1 (en) | 2003-06-02 | 2005-03-10 | Chiron Corporation | Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen |
US20060035242A1 (en) | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
DK1961426T3 (en) | 2003-10-02 | 2011-08-08 | Novartis Ag | Combination vaccines against meningitis |
DE202005022108U1 (en) | 2004-03-09 | 2013-11-12 | Novartis Vaccines And Diagnostics, Inc. | Influenza virus vaccines |
RU2379052C2 (en) | 2004-04-30 | 2010-01-20 | Чирон С.Р.Л. | Meningococcal conjugate vaccination |
GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
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JP2008504292A (en) | 2004-06-24 | 2008-02-14 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド | Immune enhancement compounds |
EP1784211A4 (en) | 2004-07-29 | 2010-06-30 | Novartis Vaccines & Diagnostic | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
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GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
SG160329A1 (en) | 2005-02-18 | 2010-04-29 | Novartis Vaccines & Diagnostic | Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli |
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DE602006020738D1 (en) | 2005-08-01 | 2011-04-28 | Hisamitsu Pharmaceutical Co | ADJUVANS OR PHARMACEUTICAL PREPARATION FOR TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION |
JP2009511636A (en) | 2005-10-18 | 2009-03-19 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド | Mucosal and systemic immunity with alphavirus replicon particles |
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AU2006310338A1 (en) * | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Adminstration routes for priming/boosting with influenza vaccines |
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GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
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WO2023135515A1 (en) | 2022-01-13 | 2023-07-20 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
WO2023161817A1 (en) | 2022-02-25 | 2023-08-31 | Pfizer Inc. | Methods for incorporating azido groups in bacterial capsular polysaccharides |
WO2023218322A1 (en) | 2022-05-11 | 2023-11-16 | Pfizer Inc. | Process for producing of vaccine formulations with preservatives |
WO2024018061A1 (en) | 2022-07-22 | 2024-01-25 | Institut National de la Santé et de la Recherche Médicale | Use of bordetella strains for the treatment of chronic obstructive pulmonary disease |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4772466A (en) * | 1983-08-22 | 1988-09-20 | Syntex (U.S.A.) Inc. | Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants |
NL8403195A (en) * | 1984-10-19 | 1986-05-16 | Nederlanden Staat | IMMUNOGENIC COMPLEXES AND VACCINES CONTAINING THESE. |
CA1291036C (en) * | 1986-04-23 | 1991-10-22 | Edwin I. Stoltz | Nasal administration of drugs |
US5653987A (en) * | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
-
2000
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- 2000-09-22 CN CN00816014A patent/CN1391483A/en active Pending
- 2000-09-22 HU HU0202885A patent/HUP0202885A3/en unknown
- 2000-09-22 JP JP2001524631A patent/JP2003509473A/en active Pending
- 2000-09-22 KR KR1020027003832A patent/KR20020038770A/en not_active Application Discontinuation
- 2000-09-22 PL PL00355163A patent/PL355163A1/en not_active Application Discontinuation
- 2000-09-22 BR BR0014282-4A patent/BR0014282A/en not_active Application Discontinuation
- 2000-09-22 CZ CZ20021043A patent/CZ20021043A3/en unknown
- 2000-09-22 TR TR2002/00774T patent/TR200200774T2/en unknown
- 2000-09-22 IL IL14867200A patent/IL148672A0/en unknown
- 2000-09-22 MX MXPA02003067A patent/MXPA02003067A/en unknown
- 2000-09-22 WO PCT/EP2000/009366 patent/WO2001021207A2/en not_active Application Discontinuation
- 2000-09-22 CO CO00072096A patent/CO5200837A1/en not_active Application Discontinuation
- 2000-09-22 AU AU79070/00A patent/AU765824B2/en not_active Ceased
- 2000-09-22 CA CA002383413A patent/CA2383413A1/en not_active Abandoned
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2002
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CN1391483A (en) | 2003-01-15 |
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WO2001021207A3 (en) | 2001-09-27 |
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CA2383413A1 (en) | 2001-03-29 |
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CO5200837A1 (en) | 2002-09-27 |
JP2003509473A (en) | 2003-03-11 |
KR20020038770A (en) | 2002-05-23 |
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