EP1163252A4 - Compositions, kits, and methods relating to the human fez1 gene, a novel tumor suppressor gene - Google Patents

Compositions, kits, and methods relating to the human fez1 gene, a novel tumor suppressor gene

Info

Publication number
EP1163252A4
EP1163252A4 EP00912007A EP00912007A EP1163252A4 EP 1163252 A4 EP1163252 A4 EP 1163252A4 EP 00912007 A EP00912007 A EP 00912007A EP 00912007 A EP00912007 A EP 00912007A EP 1163252 A4 EP1163252 A4 EP 1163252A4
Authority
EP
European Patent Office
Prior art keywords
gene
kits
compositions
tumor suppressor
methods relating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00912007A
Other languages
German (de)
French (fr)
Other versions
EP1163252A2 (en
Inventor
Carlo M Croce
Hideshi Ishii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thomas Jefferson University
Original Assignee
Thomas Jefferson University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Jefferson University filed Critical Thomas Jefferson University
Publication of EP1163252A2 publication Critical patent/EP1163252A2/en
Publication of EP1163252A4 publication Critical patent/EP1163252A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP00912007A 1999-02-25 2000-02-25 Compositions, kits, and methods relating to the human fez1 gene, a novel tumor suppressor gene Withdrawn EP1163252A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12153799P 1999-02-25 1999-02-25
US121537P 1999-02-25
PCT/US2000/004950 WO2000050565A2 (en) 1999-02-25 2000-02-25 Compositions, kits, and methods relating to the human fez1 gene, a novel tumor suppressor gene

Publications (2)

Publication Number Publication Date
EP1163252A2 EP1163252A2 (en) 2001-12-19
EP1163252A4 true EP1163252A4 (en) 2004-04-07

Family

ID=22397335

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00912007A Withdrawn EP1163252A4 (en) 1999-02-25 2000-02-25 Compositions, kits, and methods relating to the human fez1 gene, a novel tumor suppressor gene

Country Status (4)

Country Link
EP (1) EP1163252A4 (en)
JP (1) JP2003508011A (en)
CA (1) CA2361396A1 (en)
WO (1) WO2000050565A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141417B1 (en) 1999-02-25 2006-11-28 Thomas Jefferson University Compositions, kits, and methods relating to the human FEZ1 gene, a novel tumor suppressor gene
CN101918424A (en) 2007-06-15 2010-12-15 俄亥俄州立大学研究基金会 Oncogenic ALL-1 fusion proteins for targeting Drosha-mediated microRNA processing
ES2627059T3 (en) 2007-08-03 2017-07-26 The Ohio State University Research Foundation Ultraconserved regions encoding RNAnc
WO2009055773A2 (en) 2007-10-26 2009-04-30 The Ohio State University Research Foundation Methods for identifying fragile histidine triad (fhit) interaction and uses thereof
EP2307028B1 (en) 2008-06-11 2013-10-02 The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services Use of mir-26 family as a predictive marker of hepatocellular carcinoma and responsiveness to therapy
EP2504452A4 (en) 2009-11-23 2014-06-11 Univ Ohio State Res Found Materials and methods useful for affecting tumor cell growth, migration and invasion
AU2011326032B2 (en) 2010-11-12 2016-10-06 The Ohio State University Research Foundation Materials and methods related to microRNA-21, mismatch repair, and colorectal cancer
BR112013011942A2 (en) 2010-11-15 2016-11-01 Univ Michigan formulation, drug dosage form for oral transmucosal administration, transmucosal drug delivery system, method of treatment and prophylaxis of a disease or disorder, method of treatment, formulation, method for treatment or prevention of head and neck squamous cell carcinoma (hnscc), method for chemoprevention of an oral cancer or precancerous condition, method for increasing the concentration of a retinide composition, method of treatment and prophylaxis of a disease or condition, ratification method of a subject presenting a symptomatic medical condition , method of treating an oral cancer or precancerous condition in a patient, method for making an oral drug delivery system, method for increasing the release and permeation of a retinide composition.
JP2014509852A (en) 2011-03-07 2014-04-24 ジ・オハイオ・ステート・ユニバーシティ Mutagenic activity induced by microRNA-155 (miR-155) links inflammation and cancer
JP2014530612A (en) 2011-10-14 2014-11-20 ジ・オハイオ・ステート・ユニバーシティ Methods and materials for ovarian cancer
CN104619353A (en) 2011-12-13 2015-05-13 俄亥俄州国家创新基金会 Methods and compositions related to miR-21 and miR-29a, exosome inhibition, and cancer metastasis
JP2015511121A (en) 2012-01-20 2015-04-16 ジ・オハイオ・ステート・ユニバーシティ Breast cancer biomarker signature for invasiveness and prognosis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055300A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2001055448A1 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055300A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2001055448A1 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 July 1998 (1998-07-01), "ox62e04.x1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:1660926 3', mRNA sequence", XP002266794, Database accession no. AI042490 *
ISHII H ET AL: "The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. UNITED STATES 30 MAR 1999, vol. 96, no. 7, 30 March 1999 (1999-03-30), pages 3928 - 3933, XP002266793, ISSN: 0027-8424 *
See also references of WO0050565A3 *

Also Published As

Publication number Publication date
WO2000050565A2 (en) 2000-08-31
JP2003508011A (en) 2003-03-04
EP1163252A2 (en) 2001-12-19
CA2361396A1 (en) 2000-08-31
WO2000050565A3 (en) 2000-12-07

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20010912

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Ipc: 7C 07K 14/47 A

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Effective date: 20040219

RTI1 Title (correction)

Free format text: COMPOSITIONS, KITS, AND METHODS RELATING TO THE HUMAN FEZ1 GENE, A NOVEL TUMOR SUPPRESSOR GENE

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Effective date: 20051012

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