EP1139774A4 - Improved release of medicament active agents from a chewing gum coating - Google Patents

Improved release of medicament active agents from a chewing gum coating

Info

Publication number
EP1139774A4
EP1139774A4 EP99966257A EP99966257A EP1139774A4 EP 1139774 A4 EP1139774 A4 EP 1139774A4 EP 99966257 A EP99966257 A EP 99966257A EP 99966257 A EP99966257 A EP 99966257A EP 1139774 A4 EP1139774 A4 EP 1139774A4
Authority
EP
European Patent Office
Prior art keywords
active agents
chewing gum
improved release
medicament active
gum coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP99966257A
Other languages
German (de)
French (fr)
Other versions
EP1139774A1 (en
Inventor
Sonya S Johnson
David W Record
Michael J Greenberg
Michael A Reed
Victor V Gudas
Philip G Schnell
Donald A Seielstad
Henry T Typrin
Michael P Russell
David L Witkewitz
Joo H Song
Donald J Townsend
Robert J Yatka
Ronald L Ream
Christine L Corriveau
William J Wokas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WM Wrigley Jr Co
Original Assignee
WM Wrigley Jr Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WM Wrigley Jr Co filed Critical WM Wrigley Jr Co
Priority claimed from PCT/US1999/029742 external-priority patent/WO2000035296A1/en
Publication of EP1139774A1 publication Critical patent/EP1139774A1/en
Publication of EP1139774A4 publication Critical patent/EP1139774A4/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/18—Chewing gum characterised by shape, structure or physical form, e.g. aerated products
    • A23G4/20—Composite products, e.g. centre-filled, multi-layer, laminated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Physiology (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Confectionery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP99966257A 1998-12-15 1999-12-14 Improved release of medicament active agents from a chewing gum coating Ceased EP1139774A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US11238998P 1998-12-15 1998-12-15
US112389P 1998-12-15
US28681899A 1999-04-06 1999-04-06
US286818 1999-04-06
US38921199A 1999-09-02 1999-09-02
US389211 1999-09-02
PCT/US1999/029742 WO2000035296A1 (en) 1996-11-27 1999-12-14 Improved release of medicament active agents from a chewing gum coating

Publications (2)

Publication Number Publication Date
EP1139774A1 EP1139774A1 (en) 2001-10-10
EP1139774A4 true EP1139774A4 (en) 2002-06-12

Family

ID=27381160

Family Applications (2)

Application Number Title Priority Date Filing Date
EP99966257A Ceased EP1139774A4 (en) 1998-12-15 1999-12-14 Improved release of medicament active agents from a chewing gum coating
EP99966283A Withdrawn EP1221863A4 (en) 1998-12-15 1999-12-14 Chewing gum containing medicament active agents

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP99966283A Withdrawn EP1221863A4 (en) 1998-12-15 1999-12-14 Chewing gum containing medicament active agents

Country Status (5)

Country Link
EP (2) EP1139774A4 (en)
CN (1) CN1330516A (en)
AU (1) AU765999B2 (en)
BR (1) BR9916303A (en)
CA (1) CA2355779C (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8323683B2 (en) * 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
CN102008473B (en) * 2010-11-23 2014-12-17 中国人民解放军第二军医大学 Application of nicotine and medical composition
MX2020001445A (en) * 2017-08-18 2020-03-20 Intercontinental Great Brands Llc Chewing gum compositions and methods of making thereof.
WO2021144365A1 (en) * 2020-01-15 2021-07-22 Mcneil Ab Product and manufacturing process for a gum
US11272799B2 (en) * 2020-05-29 2022-03-15 Unistraw Corp. Drinking straw with internal coating

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3011949A (en) * 1958-06-10 1961-12-05 Anthony G Bilotti Method of promoting release of active ingredients from slab chewing gum and product
FR2345938A1 (en) * 1976-03-05 1977-10-28 Choay Patrick Chewing gum contg. xanthine stimulants or mixts. - including plant extracts e.g. tea and coffee extracts
US4997659A (en) * 1989-03-28 1991-03-05 The Wm. Wrigley Jr. Company Alitame stability in chewing gum by encapsulation
US5376389A (en) * 1992-03-26 1994-12-27 Wm. Wrigley Jr. Company Hard coated chewing gum with improved shelf life, with xylitol and polyol coatings
US5380530A (en) * 1992-12-29 1995-01-10 Whitehill Oral Technologies Oral care composition coated gum
US5487902A (en) * 1989-07-24 1996-01-30 Fertin Laboratories Ltd. (Dansk Tyggegummi Fabrik A/S) Chewing gum composition with accelerated, controlled release of active agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1298670A (en) * 1915-06-11 1919-04-01 Stuart W Cramer Chewing-gum.
US4238475A (en) * 1979-08-01 1980-12-09 Life Savers Inc. Chewing cum capable of releasing finely divided water-insoluble materials therefrom
US4971787A (en) * 1984-08-27 1990-11-20 Warner-Lambert Company Antacid chewing gum
US5013716A (en) * 1988-10-28 1991-05-07 Warner-Lambert Company Unpleasant taste masking compositions and methods for preparing same
US5139794A (en) * 1989-04-19 1992-08-18 Wm. Wrigley Jr. Company Use of encapsulated salts in chewing gum
US5286502A (en) * 1992-04-21 1994-02-15 Wm. Wrigley Jr. Company Use of edible film to prolong chewing gum shelf life
DK0719093T3 (en) * 1993-09-15 2000-06-05 Wrigley W M Jun Co Chewing gum with hard coating and improved durability and with mixed polyocoating
WO1995007625A1 (en) * 1993-09-15 1995-03-23 Wm. Wrigley Jr. Company Chewing gum pellet having a hard coating containing erythritol
AU6591696A (en) * 1995-07-26 1997-02-26 Wm. Wrigley Jr. Company Use of encapsulated aspartic acid sweeteners in coating syrups for coated pellet chewing gums
CA2271889C (en) * 1996-11-27 2004-01-27 Wm. Wrigley Jr. Company Method of controlling release of caffeine in chewing gum and gum produced thereby

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3011949A (en) * 1958-06-10 1961-12-05 Anthony G Bilotti Method of promoting release of active ingredients from slab chewing gum and product
FR2345938A1 (en) * 1976-03-05 1977-10-28 Choay Patrick Chewing gum contg. xanthine stimulants or mixts. - including plant extracts e.g. tea and coffee extracts
US4997659A (en) * 1989-03-28 1991-03-05 The Wm. Wrigley Jr. Company Alitame stability in chewing gum by encapsulation
US5487902A (en) * 1989-07-24 1996-01-30 Fertin Laboratories Ltd. (Dansk Tyggegummi Fabrik A/S) Chewing gum composition with accelerated, controlled release of active agents
US5376389A (en) * 1992-03-26 1994-12-27 Wm. Wrigley Jr. Company Hard coated chewing gum with improved shelf life, with xylitol and polyol coatings
US5380530A (en) * 1992-12-29 1995-01-10 Whitehill Oral Technologies Oral care composition coated gum

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0035296A1 *

Also Published As

Publication number Publication date
EP1139774A1 (en) 2001-10-10
EP1221863A4 (en) 2003-03-26
CA2355779C (en) 2006-02-07
CA2355779A1 (en) 2000-06-22
BR9916303A (en) 2001-10-02
EP1221863A1 (en) 2002-07-17
AU765999B2 (en) 2003-10-09
AU2184300A (en) 2000-07-03
CN1330516A (en) 2002-01-09

Similar Documents

Publication Publication Date Title
PL350925A1 (en) Long flavor duration releasing structures for chewing gum
PL341428A1 (en) Oral pharmacological dosage form of prolonged release type
HUP0103883A3 (en) New sustained release oral formulations
AU3977099A (en) Controlled release oral dosage form
EP1408867A4 (en) Breakaway devices for stabilizing dental casts
EP1014805A4 (en) Chewing gum containing physiological cooling agents
EP1139773A4 (en) Controlling release of active agents from a chewing gum coating
PL342345A1 (en) Active substance suspension for oral administration
ZA988718B (en) Drug formulation having controlled release of active compound
IL138192A0 (en) Controlled release oral dosage forms
PL356454A1 (en) Release of lipophilic active agents from chewing gum
SG63824A1 (en) Rapamycin formulations for oral administration
HUP0004407A3 (en) Immediate and modified release oral dosage formulations containing eprosartan and processes for their manufacture
EP1139774A4 (en) Improved release of medicament active agents from a chewing gum coating
HUP0003341A3 (en) Rapamycin formulations for oral administration
HUP0201667A2 (en) Oral form of administration
HUP0202744A3 (en) Oral controlled release formulations containing rivastigmine
AU4964200A (en) Prevention of dental caries
EP1032276A4 (en) Chewing gum containing trehalose
PL325509A1 (en) Therapeutic agent for oral administration
GB9907207D0 (en) Tooth 'n' gum chewing gum
GB9905740D0 (en) Tooth 'n' gum chewing gum
AU2002300700A1 (en) Chewing Gum Containing Physiological Cooling Agents
TW326157U (en) Dental floss dispenser
GB9619063D0 (en) Oral coated active drugs

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010715

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

Kind code of ref document: A1

Designated state(s): DE DK FR GB IT NL

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

A4 Supplementary search report drawn up and despatched

Effective date: 20020426

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): DE DK FR GB IT NL

RIC1 Information provided on ipc code assigned before grant

Free format text: 7A 23G 3/30 A, 7A 61K 9/68 B, 7A 23G 3/00 B

RBV Designated contracting states (corrected)

Designated state(s): DE DK FR GB IT NL

RIN1 Information on inventor provided before grant (corrected)

Inventor name: WOKAS, WILLIAM, J.

Inventor name: CORRIVEAU, CHRISTINE, L.

Inventor name: REAM, RONALD, L.

Inventor name: YATKA, ROBERT, J.

Inventor name: TOWNSEND, DONALD, J.

Inventor name: SONG, JOO H.

Inventor name: WITKEWITZ, DAVID, L.

Inventor name: RUSSELL, MICHAEL, P.

Inventor name: TYPRIN, HENRY, T.

Inventor name: SEIELSTAD, DONALD, A.

Inventor name: SCHNELL, PHILIP, G.

Inventor name: GUDAS, VICTOR V.

Inventor name: REED, MICHAEL, A.

Inventor name: GREENBERG, MICHAEL, J.

Inventor name: RECORD, DAVID, W.

Inventor name: JOHNSON, SONYA, S.

17Q First examination report despatched

Effective date: 20070911

REG Reference to a national code

Ref country code: DE

Ref legal event code: R003

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 20110702