EP1056413A4 - Injectable implants for tissue augmentation and restoration - Google Patents

Injectable implants for tissue augmentation and restoration

Info

Publication number
EP1056413A4
EP1056413A4 EP99908590A EP99908590A EP1056413A4 EP 1056413 A4 EP1056413 A4 EP 1056413A4 EP 99908590 A EP99908590 A EP 99908590A EP 99908590 A EP99908590 A EP 99908590A EP 1056413 A4 EP1056413 A4 EP 1056413A4
Authority
EP
European Patent Office
Prior art keywords
restoration
tissue augmentation
injectable implants
implants
injectable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99908590A
Other languages
German (de)
French (fr)
Other versions
EP1056413A1 (en
Inventor
Dan W Urry
Timothy M Parker
Paul A Glazer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioelastics Research Ltd
Original Assignee
Bioelastics Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioelastics Research Ltd filed Critical Bioelastics Research Ltd
Publication of EP1056413A1 publication Critical patent/EP1056413A1/en
Publication of EP1056413A4 publication Critical patent/EP1056413A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4601Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/38Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Yarns And Mechanical Finishing Of Yarns Or Ropes (AREA)
EP99908590A 1998-02-27 1999-02-26 Injectable implants for tissue augmentation and restoration Withdrawn EP1056413A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7629798P 1998-02-27 1998-02-27
US76297P 1998-02-27
US8715598P 1998-05-29 1998-05-29
US87155P 1998-05-29
PCT/US1999/004440 WO1999043271A1 (en) 1998-02-27 1999-02-26 Injectable implants for tissue augmentation and restoration

Publications (2)

Publication Number Publication Date
EP1056413A1 EP1056413A1 (en) 2000-12-06
EP1056413A4 true EP1056413A4 (en) 2003-08-20

Family

ID=26757929

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99908590A Withdrawn EP1056413A4 (en) 1998-02-27 1999-02-26 Injectable implants for tissue augmentation and restoration

Country Status (6)

Country Link
US (3) US6699294B2 (en)
EP (1) EP1056413A4 (en)
JP (1) JP2002507437A (en)
AU (1) AU2798599A (en)
CA (1) CA2319558A1 (en)
WO (1) WO1999043271A1 (en)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998020939A2 (en) 1996-11-15 1998-05-22 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
EP1056413A4 (en) * 1998-02-27 2003-08-20 Bioelastics Res Ltd Injectable implants for tissue augmentation and restoration
AU3867400A (en) * 1999-03-19 2000-10-09 Duke University Methods of using bioelastomers
US6662805B2 (en) * 1999-03-24 2003-12-16 The Johns Hopkins University Method for composite cell-based implants
EP1229940B1 (en) 1999-11-15 2014-05-14 Piramal Healthcare (Canada) Limited Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
DE60033055D1 (en) 1999-12-06 2007-03-08 Warsaw Orthopedic Inc LUMBAR TREATMENT DEVICE
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
US20020082220A1 (en) 2000-06-29 2002-06-27 Hoemann Caroline D. Composition and method for the repair and regeneration of cartilage and other tissues
US6685626B2 (en) * 2001-02-02 2004-02-03 Regeneration Technologies, Inc. Compositions, devices, methods, and kits for induction of adhesions
US20070078435A1 (en) * 2001-06-14 2007-04-05 Corbett Stone Tissue augmentation methods using a medical injection apparatus
WO2003095016A1 (en) * 2002-05-08 2003-11-20 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US20040106896A1 (en) * 2002-11-29 2004-06-03 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US7439067B2 (en) * 2002-05-20 2008-10-21 Battelle Memorial Institute Isolated polynucleotides and methods of promoting a morphology in a fungus
WO2004026190A2 (en) * 2002-09-18 2004-04-01 Sdgi Holdings, Inc. Natural tissue devices and methods of implantation
US7744651B2 (en) * 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
US7309359B2 (en) * 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
US20040054414A1 (en) 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
JP2006515765A (en) * 2002-11-15 2006-06-08 エスディージーアイ・ホールディングス・インコーポレーテッド Collagen-based materials and methods for treating synovial joints
US7317950B2 (en) * 2002-11-16 2008-01-08 The Regents Of The University Of California Cardiac stimulation system with delivery of conductive agent
US20040186471A1 (en) * 2002-12-07 2004-09-23 Sdgi Holdings, Inc. Method and apparatus for intervertebral disc expansion
US7597660B2 (en) * 2003-09-19 2009-10-06 Broockeville Corporation B.V. Incontinence therapy
EP2193812A1 (en) * 2003-09-19 2010-06-09 Broockeville Corporation N.V. Use of a curable elastomer-precursor for a medical treatment
US20050113923A1 (en) * 2003-10-03 2005-05-26 David Acker Prosthetic spinal disc nucleus
EP1684816B1 (en) * 2003-10-28 2009-05-06 Medtronic, Inc. Methods of preparing crosslinked materials and bioprosthetic devices
WO2005079821A1 (en) * 2004-02-13 2005-09-01 Intercytex Limited Wound healing profile
US8945223B2 (en) * 2004-03-12 2015-02-03 Warsaw Orthopedic, Inc. In-situ formable nucleus pulposus implant with water absorption and swelling capability
US20050209695A1 (en) * 2004-03-15 2005-09-22 De Vries Jan A Vertebroplasty method
CA2571815A1 (en) * 2004-06-23 2006-01-05 National Research Council Of Canada Polypeptide ligands containing linkers
US7442389B2 (en) * 2004-08-20 2008-10-28 Artes Medical, Inc. Methods of administering microparticles combined with autologous body components
US7367961B2 (en) * 2004-09-10 2008-05-06 Depuy Spine, Inc. Intradiscal injection of autologous interferon
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US20080312156A1 (en) * 2005-01-18 2008-12-18 Duke University In-Situ Crosslinkable Elastin-Like Polypeptides for Defect Filling in Cartilaginous Tissue Repair
GB0505202D0 (en) * 2005-03-14 2005-04-20 Intercytex Ltd Skin equivalent culture
US20060253198A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Multi-lumen mold for intervertebral prosthesis and method of using same
US20060253199A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Lordosis creating nucleus replacement method and apparatus
AU2006251004C1 (en) * 2005-05-26 2013-05-23 Intercytex Limited Tissue repair using allogenic dermal fibroblasts
EP1890749A1 (en) * 2005-06-16 2008-02-27 Artes Medical, Inc. Liquid crystal polymer syringes and containers and methods of use for long term storage of filler materials
CN101500606B (en) * 2005-06-24 2013-12-04 杜克大学 A direct drug delivery system based on thermally responsive biopolymers
US20070102010A1 (en) * 2005-10-07 2007-05-10 Lemperle Stefan M Naso-pharyngeal tissue engineering
WO2007073486A2 (en) 2005-12-20 2007-06-28 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US20080086200A1 (en) * 2006-01-03 2008-04-10 Heartcor Injectable implants for tissue augmentation and restoration
US7709227B2 (en) * 2006-01-04 2010-05-04 Phasebio Pharmaceuticals, Inc. Multimeric ELP fusion constructs
US8518105B2 (en) * 2006-03-24 2013-08-27 Abbott Cardiovascular System Inc. Methods and apparatuses for coating a lesion
US8092536B2 (en) * 2006-05-24 2012-01-10 Disc Dynamics, Inc. Retention structure for in situ formation of an intervertebral prosthesis
US20070276491A1 (en) * 2006-05-24 2007-11-29 Disc Dynamics, Inc. Mold assembly for intervertebral prosthesis
KR20070122316A (en) * 2006-06-26 2007-12-31 (주) 에스바이오메딕스 Soft tissue filler composition for injection and preparation method thereof
KR20070122315A (en) * 2006-06-26 2007-12-31 (주) 에스바이오메딕스 Soft tissue filler composition comprising autologous dermal cell and hyaluronic acid
US20080004431A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic Inc Method of manufacturing an injectable collagen material
US20080004703A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic, Inc. Method of treating a patient using a collagen material
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US20080097229A1 (en) * 2006-08-29 2008-04-24 Josee Roy Hygroscopic treatment for degenerating discs
WO2008058323A1 (en) * 2006-11-13 2008-05-22 The University Of Sydney Use of tropoelastin for repair or restoration of tissue
US20090036656A1 (en) * 2007-07-31 2009-02-05 Body Organ Biomedical Corp. Method for preparing a biomaterial
US20110212524A1 (en) * 2006-12-04 2011-09-01 Body Organ Biomedical Corporation Biomaterial and preparation method thereof
US20080177389A1 (en) * 2006-12-21 2008-07-24 Rob Gene Parrish Intervertebral disc spacer
US8383586B2 (en) * 2007-01-18 2013-02-26 Warsaw Orthopedic, Inc. Compositions and methods for soft tissue repair
CA2685956A1 (en) * 2007-05-04 2008-11-13 Perth Bone & Tissue Bank A method for treating inflammation and controlled-release material capable of providing same
US20090098110A1 (en) * 2007-05-30 2009-04-16 Duke University Injectable forms of solid-forming crosslinked bioelastic biopolymers for local drug delivery
WO2009151520A2 (en) * 2008-05-09 2009-12-17 Surmodics Pharmaceuticals, Inc. Biocompatible and biodegradable elastomeric polymers
EP2307038A4 (en) 2008-06-27 2013-03-27 Univ Duke Therapeutic agents comprising elastin-like peptides
US20100081928A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological Facilitation systems and methods
ES2870914T3 (en) * 2009-08-14 2021-10-28 Phasebio Pharmaceuticals Inc Modified vasoactive intestinal peptides
CA2873553C (en) 2011-06-06 2020-01-28 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
JP6157877B2 (en) * 2012-02-28 2017-07-05 三洋化成工業株式会社 Tissue regeneration gel, protein solution for tissue regeneration, and method for producing gel for tissue regeneration
ES2818824T3 (en) 2014-05-08 2021-04-14 Phasebio Pharmaceuticals Inc Compositions comprising a VIP-ELP fusion protein for use in the treatment of cystic fibrosis
JP2018500395A (en) * 2014-12-15 2018-01-11 ノースイースタン・ユニバーシティ Collagen tissue treatment device
ES2822598T3 (en) 2015-02-09 2021-05-04 Phasebio Pharmaceuticals Inc Methods and Compositions for Treating Muscle Diseases and Disorders
EP3981450A1 (en) * 2015-02-27 2022-04-13 Amgen, Inc Drug delivery device having a needle guard mechanism with a tunable threshold of resistance to needle guard movement
JP6775227B2 (en) * 2016-07-08 2020-10-28 田畑 泰彦 Cell transplantation composition and cell transplantation solution containing it
KR102173702B1 (en) * 2018-11-27 2020-11-03 가톨릭대학교 산학협력단 Peptides for targeting skin cells and use thereof
KR20220023962A (en) * 2019-03-27 2022-03-03 시질론 테라퓨틱스, 인크. Compositions, devices and methods for treating Fabry disease
CN111939244A (en) 2019-05-14 2020-11-17 阿莫生命科学有限公司 Pharmaceutical composition for preventing or treating diabetic complications
WO2021040526A1 (en) * 2019-08-30 2021-03-04 Biotempt B.V. Q-er peptide

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989010099A1 (en) * 1988-04-21 1989-11-02 Uab Research Foundation Bioelastomeric materials suitable for the protection of wound repair sites from the occurrence of adhesions
WO1989010098A1 (en) * 1988-04-21 1989-11-02 Uab Research Foundation Stimulation of chemotaxis by chemotactic peptides
EP0449592A1 (en) * 1990-03-27 1991-10-02 Bioelastics Research, Ltd. Bioelastomeric drug delivery system
US5393602A (en) * 1991-04-19 1995-02-28 Bioelastics Research Ltd. Superabsorbent materials and uses thereof
US5519004A (en) * 1994-05-20 1996-05-21 The Uab Research Foundation Elastomeric polypeptide matrices for preventing adhesion of biological materials

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5336256A (en) * 1986-04-17 1994-08-09 Uab Research Foundation Elastomeric polypeptides as vascular prosthetic materials
US4870055A (en) * 1986-04-17 1989-09-26 University Of Alabama At Birmingham Segmented polypeptide bioelastomers to modulate elastic modulus
US5250516A (en) 1986-04-17 1993-10-05 Uab Research Foundation Bioelastomeric materials suitable for the protection of burn areas or the protection of wound repair sites from the occurrence of adhesions
US4898926A (en) * 1987-06-15 1990-02-06 The University Of Alabama At Birmingham/Research Foundation Bioelastomer containing tetra/penta-peptide units
US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5226292A (en) * 1991-04-22 1993-07-13 Uab Research Foundation Polymers capable of baromechanical and barochemical transduction
US5428022A (en) 1992-07-29 1995-06-27 Collagen Corporation Composition of low type III content human placental collagen
WO1995026761A1 (en) 1994-04-04 1995-10-12 Collagen Corporation Cell-gels
ATE203885T1 (en) * 1994-09-08 2001-08-15 Stryker Technologies Corp HYDROGEL DISC CORE
DK2111876T3 (en) * 1995-12-18 2011-12-12 Angiodevice Internat Gmbh Crosslinked polymer preparations and methods for their use
EP1056413A4 (en) * 1998-02-27 2003-08-20 Bioelastics Res Ltd Injectable implants for tissue augmentation and restoration
US6132465A (en) * 1998-06-04 2000-10-17 Raymedica, Inc. Tapered prosthetic spinal disc nucleus
US6352557B1 (en) * 1999-08-13 2002-03-05 Bret A. Ferree Treating degenerative disc disease through transplantion of extracellular nucleus pulposus matrix and autograft nucleus pulposus cells
US6264695B1 (en) * 1999-09-30 2001-07-24 Replication Medical, Inc. Spinal nucleus implant

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989010099A1 (en) * 1988-04-21 1989-11-02 Uab Research Foundation Bioelastomeric materials suitable for the protection of wound repair sites from the occurrence of adhesions
WO1989010098A1 (en) * 1988-04-21 1989-11-02 Uab Research Foundation Stimulation of chemotaxis by chemotactic peptides
EP0449592A1 (en) * 1990-03-27 1991-10-02 Bioelastics Research, Ltd. Bioelastomeric drug delivery system
US5393602A (en) * 1991-04-19 1995-02-28 Bioelastics Research Ltd. Superabsorbent materials and uses thereof
US5519004A (en) * 1994-05-20 1996-05-21 The Uab Research Foundation Elastomeric polypeptide matrices for preventing adhesion of biological materials

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9943271A1 *

Also Published As

Publication number Publication date
US20020116069A1 (en) 2002-08-22
US6699294B2 (en) 2004-03-02
JP2002507437A (en) 2002-03-12
WO1999043271A1 (en) 1999-09-02
EP1056413A1 (en) 2000-12-06
US6533819B1 (en) 2003-03-18
AU2798599A (en) 1999-09-15
CA2319558A1 (en) 1999-09-02
US20020038150A1 (en) 2002-03-28

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