EP0938299A4 - Methods for the production of protein particles useful for delivery of pharmacological agents - Google Patents

Methods for the production of protein particles useful for delivery of pharmacological agents

Info

Publication number
EP0938299A4
EP0938299A4 EP97936517A EP97936517A EP0938299A4 EP 0938299 A4 EP0938299 A4 EP 0938299A4 EP 97936517 A EP97936517 A EP 97936517A EP 97936517 A EP97936517 A EP 97936517A EP 0938299 A4 EP0938299 A4 EP 0938299A4
Authority
EP
European Patent Office
Prior art keywords
delivery
production
methods
pharmacological agents
protein particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97936517A
Other languages
German (de)
French (fr)
Other versions
EP0938299A1 (en
Inventor
Shlomo Magdassi
Neil Desai
Kevin Ferreri
Patrick Soon-Shiong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abraxis Bioscience LLC
Original Assignee
Vivorx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vivorx Pharmaceuticals Inc filed Critical Vivorx Pharmaceuticals Inc
Priority to EP06007715A priority Critical patent/EP1683517A1/en
Publication of EP0938299A1 publication Critical patent/EP0938299A1/en
Publication of EP0938299A4 publication Critical patent/EP0938299A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
EP97936517A 1996-08-19 1997-08-19 Methods for the production of protein particles useful for delivery of pharmacological agents Withdrawn EP0938299A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06007715A EP1683517A1 (en) 1996-08-19 1997-08-19 Methods for the production of protein particles useful for delivery of pharmacological agents

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2396896P 1996-08-19 1996-08-19
US23968P 1996-08-19
PCT/US1997/014661 WO1998007410A1 (en) 1996-08-19 1997-08-19 Methods for the production of protein particles useful for delivery of pharmacological agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP06007715A Division EP1683517A1 (en) 1996-08-19 1997-08-19 Methods for the production of protein particles useful for delivery of pharmacological agents

Publications (2)

Publication Number Publication Date
EP0938299A1 EP0938299A1 (en) 1999-09-01
EP0938299A4 true EP0938299A4 (en) 2001-01-17

Family

ID=21818165

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97936517A Withdrawn EP0938299A4 (en) 1996-08-19 1997-08-19 Methods for the production of protein particles useful for delivery of pharmacological agents

Country Status (4)

Country Link
EP (1) EP0938299A4 (en)
AU (1) AU3916997A (en)
CA (1) CA2263765C (en)
WO (1) WO1998007410A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6254890B1 (en) 1997-12-12 2001-07-03 Massachusetts Institute Of Technology Sub-100nm biodegradable polymer spheres capable of transporting and releasing nucleic acids
JP4516273B2 (en) * 2000-11-15 2010-08-04 ミナーヴァ・バイオテクノロジーズ・コーポレーション Oligonucleotide identifier
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
EP1392245A2 (en) * 2001-04-05 2004-03-03 Universite Laval Process for making protein delivery matrix and uses thereof
IL160570A0 (en) 2001-09-26 2004-07-25 Baxter Int Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
JP4212921B2 (en) * 2002-03-29 2009-01-21 独立行政法人科学技術振興機構 Therapeutic agents using protein hollow nanoparticles presenting antibodies and protein hollow nanoparticles
IL150906A0 (en) 2002-07-25 2003-02-12 Yissum Res Dev Co Diagnostic microspheres
SI1585548T1 (en) 2002-12-09 2018-11-30 Abraxis Bioscience, Llc Compositions and methods of delivery of pharmacological agents
FR2902007B1 (en) * 2006-06-09 2012-01-13 Flamel Tech Sa PHARMACEUTICAL FORMULATIONS FOR PROLONGED DELIVERY OF ACTIVE (S) PRINCIPLE (S) AND THEIR PARTICULARLY THERAPEUTIC APPLICATIONS
RU2576609C2 (en) 2010-06-04 2016-03-10 АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи Methods of treating pancreatic cancer
EP2510930A1 (en) 2011-04-15 2012-10-17 Bionanoplus, S.L. Nanoparticles comprising half esters of poly (methyl vinyl ether-co-maleic anhydride) and uses thereof
MX2017005692A (en) 2014-10-31 2017-08-07 Glaxosmithkline Ip Dev Ltd Powder formulation.
CN110302364A (en) * 2019-06-24 2019-10-08 浙江工商大学 A kind of self assembly catalase nano particle and its preparation method and application
CN115154651B (en) * 2022-06-23 2023-10-27 华中科技大学 Biomineralization bovine serum albumin @ calcium selenium nanosphere, preparation method and application

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5753232A (en) * 1980-09-16 1982-03-30 Snow Brand Milk Prod Co Ltd Preparation of microcapsule
WO1992017213A1 (en) * 1991-03-28 1992-10-15 Nycomed Imaging As Improvements in or relating to contrast agents
JPH07328416A (en) * 1994-06-10 1995-12-19 Kiteii:Kk Fine particle in which physiologically active material is sealed, and its production

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585112A (en) * 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5753232A (en) * 1980-09-16 1982-03-30 Snow Brand Milk Prod Co Ltd Preparation of microcapsule
WO1992017213A1 (en) * 1991-03-28 1992-10-15 Nycomed Imaging As Improvements in or relating to contrast agents
JPH07328416A (en) * 1994-06-10 1995-12-19 Kiteii:Kk Fine particle in which physiologically active material is sealed, and its production

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 8218, Derwent World Patents Index; AN 1982-36391E, XP002154304 *
DATABASE WPI Week 896, Derwent World Patents Index; AN 1996-072972, XP002152530 *
See also references of WO9807410A1 *

Also Published As

Publication number Publication date
WO1998007410A1 (en) 1998-02-26
EP0938299A1 (en) 1999-09-01
CA2263765A1 (en) 1998-02-26
AU3916997A (en) 1998-03-06
CA2263765C (en) 2010-03-30

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