EP0721328A4 - Camptothecin formulations - Google Patents
Camptothecin formulationsInfo
- Publication number
- EP0721328A4 EP0721328A4 EP94929892A EP94929892A EP0721328A4 EP 0721328 A4 EP0721328 A4 EP 0721328A4 EP 94929892 A EP94929892 A EP 94929892A EP 94929892 A EP94929892 A EP 94929892A EP 0721328 A4 EP0721328 A4 EP 0721328A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- camptothecin formulations
- camptothecin
- formulations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12720893A | 1993-09-27 | 1993-09-27 | |
PCT/US1994/010898 WO1995008986A1 (en) | 1993-09-27 | 1994-09-27 | Camptothecin formulations |
US127208 | 1998-07-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0721328A1 EP0721328A1 (en) | 1996-07-17 |
EP0721328A4 true EP0721328A4 (en) | 1997-09-17 |
Family
ID=22428860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94929892A Withdrawn EP0721328A4 (en) | 1993-09-27 | 1994-09-27 | Camptothecin formulations |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0721328A4 (en) |
JP (1) | JPH09504517A (en) |
WO (1) | WO1995008986A1 (en) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL115099A (en) * | 1994-10-14 | 1999-04-11 | Upjohn Co | Lyophilizate of phospholipid complex of water insoluble camptothecins |
US5827533A (en) | 1997-02-06 | 1998-10-27 | Duke University | Liposomes containing active agents aggregated with lipid surfactants |
AU751439B2 (en) * | 1997-09-16 | 2002-08-15 | Osi Pharmaceuticals, Inc. | Liposomal camptothecin formulations |
US6200598B1 (en) | 1998-06-18 | 2001-03-13 | Duke University | Temperature-sensitive liposomal formulation |
US6726925B1 (en) | 1998-06-18 | 2004-04-27 | Duke University | Temperature-sensitive liposomal formulation |
EP1121102B1 (en) * | 1998-09-16 | 2003-04-23 | Alza Corporation | Liposome-entrapped topoisomerase inhibitors |
AU778340B2 (en) * | 1999-01-27 | 2004-12-02 | Telik, Inc. | Therapeutic compositions containing glutathione analogs |
US7311924B2 (en) | 1999-04-01 | 2007-12-25 | Hana Biosciences, Inc. | Compositions and methods for treating cancer |
DE60115044T2 (en) * | 2000-06-30 | 2006-08-03 | Inex Pharmaceuticals Corp., Burnaby | Liposomal antineoplastic drugs and their uses |
US7452550B2 (en) | 2000-06-30 | 2008-11-18 | Hana Biosciences, Inc. | Liposomal antineoplastic drugs and uses thereof |
CA2455170A1 (en) | 2000-07-31 | 2002-02-07 | Ottawa Heart Institute Research Corporation | Charged phospholipid compositions and methods for their use |
PL363618A1 (en) * | 2000-11-09 | 2004-11-29 | Neopharm, Inc. | Sn-38 lipid complexes and methods of use |
AU2002255810A1 (en) * | 2001-03-20 | 2002-10-03 | New Century Pharmaceuticals, Inc. | Method and compositions for optimizing blood and tissue stability of camptothecin and other albumin-binding therapeutic compounds |
DE10157994A1 (en) * | 2001-05-25 | 2003-01-02 | G O T Therapeutics Gmbh | Liposomally encapsulated hydrophobic active ingredients with a high active ingredient content> 50% and methods for producing pharmaceutical preparations which comprise liposomally encapsulated hydrophobic active ingredients |
WO2003030864A1 (en) * | 2001-05-29 | 2003-04-17 | Neopharm, Inc. | Liposomal formulation of irinotecan |
GB0207653D0 (en) * | 2002-04-03 | 2002-05-15 | Lamellar Therapeutics Ltd | Methods of using lamellar bodies for therapeutic purposes |
DE60335279D1 (en) * | 2002-06-26 | 2011-01-20 | Medigene Ag | NEW METHOD FOR STABILIZING DIAGNOSTIC AND THERAPEUTIC COMPOUNDS IN A CATIONIC CARRIER SYSTEM |
EP1393719A1 (en) * | 2002-08-23 | 2004-03-03 | Munich Biotech AG | Camptothecin-carboxylate formulations |
EP1629111B1 (en) | 2003-05-30 | 2008-05-28 | University Of Chicago | Methods and compositions for predicting irinotecan toxicity |
WO2005002546A1 (en) * | 2003-06-27 | 2005-01-13 | Smithkline Beecham Corporation | Stabilized topotecan liposomal composition and methods |
GB0322448D0 (en) | 2003-09-25 | 2003-10-29 | Lamellar Therapeutics Ltd | Using lamellar bodies to modify linear biological macro molecules |
CA2566559C (en) | 2004-05-17 | 2014-05-06 | Inex Pharmaceuticals Corporation | Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof |
CN100356919C (en) * | 2004-05-31 | 2007-12-26 | 上海医药工业研究院 | Hydroxycamptothecin liposome and its preparation |
MXPA06013874A (en) | 2004-06-01 | 2007-04-25 | Terumo Corp | Irinotecan preparation. |
WO2005123078A1 (en) * | 2004-06-18 | 2005-12-29 | Terumo Kabushiki Kaisha | Liposome preparation containing slightly water-soluble camptothecin |
EP1807051A2 (en) * | 2004-11-05 | 2007-07-18 | Inex Pharmaceuticals Corporation | Compositions and methods for stabilizing liposomal camptothecin formulations |
EP1676568A1 (en) * | 2004-12-30 | 2006-07-05 | Merckle Gmbh | Particles comprising phospholipids, process of preparation and use as medicament |
US8206750B2 (en) | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
EP2516010A2 (en) | 2009-12-23 | 2012-10-31 | Novartis AG | Lipids, lipid compositions, and methods of using them |
CN102516258B (en) * | 2011-11-11 | 2014-06-25 | 正大天晴药业集团股份有限公司 | Water-soluble vitamin E derivative modified fat-soluble anti-cancer drug compound and preparation, preparation method and application of compound |
WO2014015027A1 (en) * | 2012-07-18 | 2014-01-23 | Onyx Therapeutics, Inc. | Liposomal compositions of epoxyketone-based proteasome inhibitors |
CN104837483B (en) | 2012-11-20 | 2017-09-01 | 光谱医药公司 | The improved method for preparing the liposome packaged type vincristine of therapeutical uses |
MX2015011955A (en) | 2013-03-08 | 2016-04-07 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents. |
US10426737B2 (en) | 2013-12-19 | 2019-10-01 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
EP3083556B1 (en) | 2013-12-19 | 2019-12-25 | Novartis AG | Lipids and lipid compositions for the delivery of active agents |
EP3169309B1 (en) | 2014-07-16 | 2023-05-10 | Novartis AG | Method of encapsulating a nucleic acid in a lipid nanoparticle host |
EP3188760B1 (en) | 2014-09-05 | 2023-12-06 | Novartis AG | Lipids and lipid compositions for the delivery of active agents |
TWI678213B (en) | 2015-07-22 | 2019-12-01 | 美商史倍壯製藥公司 | A ready-to-use formulation for vincristine sulfate liposome injection |
PL439632A1 (en) * | 2021-11-23 | 2023-05-29 | Uniwersytet Warszawski | Lipid drug carrier, a pharmaceutical formulation, uses thereof and method for producing a lipid drug carrier, a carrier prepared by such method and its applications |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994026253A1 (en) * | 1993-05-19 | 1994-11-24 | The Liposome Company, Inc. | Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4721612A (en) * | 1984-04-12 | 1988-01-26 | The Liposome Company, Inc. | Steroidal liposomes |
-
1994
- 1994-09-27 JP JP7510405A patent/JPH09504517A/en active Pending
- 1994-09-27 EP EP94929892A patent/EP0721328A4/en not_active Withdrawn
- 1994-09-27 WO PCT/US1994/010898 patent/WO1995008986A1/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994026253A1 (en) * | 1993-05-19 | 1994-11-24 | The Liposome Company, Inc. | Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer |
Non-Patent Citations (1)
Title |
---|
See also references of WO9508986A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1995008986A1 (en) | 1995-04-06 |
EP0721328A1 (en) | 1996-07-17 |
JPH09504517A (en) | 1997-05-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19960402 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): BE CH DE FR GB IT LI NL |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19970731 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): BE CH DE FR GB IT LI NL |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20000401 |