EP0684834A4 - Microemulsions comprising therapeutic peptides. - Google Patents

Microemulsions comprising therapeutic peptides.

Info

Publication number
EP0684834A4
EP0684834A4 EP94909810A EP94909810A EP0684834A4 EP 0684834 A4 EP0684834 A4 EP 0684834A4 EP 94909810 A EP94909810 A EP 94909810A EP 94909810 A EP94909810 A EP 94909810A EP 0684834 A4 EP0684834 A4 EP 0684834A4
Authority
EP
European Patent Office
Prior art keywords
microemulsions
therapeutic peptides
peptides
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94909810A
Other languages
German (de)
French (fr)
Other versions
EP0684834A1 (en
Inventor
Panayiotis Peri Constantinides
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0684834A1 publication Critical patent/EP0684834A1/en
Publication of EP0684834A4 publication Critical patent/EP0684834A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/25Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
EP94909810A 1993-02-17 1994-02-17 Microemulsions comprising therapeutic peptides. Withdrawn EP0684834A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1895693A 1993-02-17 1993-02-17
US18956 1993-02-17
PCT/US1994/002062 WO1994019003A1 (en) 1993-02-17 1994-02-17 Microemulsions comprising therapeutic peptides

Publications (2)

Publication Number Publication Date
EP0684834A1 EP0684834A1 (en) 1995-12-06
EP0684834A4 true EP0684834A4 (en) 1996-09-25

Family

ID=21790620

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94909810A Withdrawn EP0684834A4 (en) 1993-02-17 1994-02-17 Microemulsions comprising therapeutic peptides.

Country Status (3)

Country Link
EP (1) EP0684834A4 (en)
JP (1) JPH08507078A (en)
WO (1) WO1994019003A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
WO1995014037A1 (en) * 1993-11-17 1995-05-26 Ibah, Inc. Transparent liquid for encapsulated drug delivery
CA2185803C (en) * 1994-03-18 2006-07-11 Edward M. Rudnic Emulsified drug delivery systems
GB9613858D0 (en) 1996-07-02 1996-09-04 Cortecs Ltd Hydrophobic preparations
EP1512398A1 (en) 1997-03-31 2005-03-09 Boston Scientific Limited Intravascular stent with cytoskeletal inhibitors for the prevention of restenosis
SE9703691D0 (en) 1997-10-10 1997-10-10 Astra Ab Pharmaceutical compositions
EP1498143A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Self-emulsifying and self-microemulsifying formulations for the oral administration of taxoids
US9028852B2 (en) 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
WO2008145728A1 (en) * 2007-06-01 2008-12-04 Novo Nordisk A/S Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier
RU2571857C2 (en) 2008-03-18 2015-12-20 Ново Нордиск А/С Acylated insulin analogues stabilised with respect to proteases
GB201107629D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Hydrophobic preparations
GB201107630D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Microemulsions
CA2870313A1 (en) 2012-04-11 2013-10-17 Novo Nordisk A/S Insulin formulations
TWI700091B (en) 2016-12-16 2020-08-01 丹麥商諾佛 儂迪克股份有限公司 Insulin containing pharmaceutical compositions
WO2020109934A1 (en) * 2018-11-30 2020-06-04 3M Innovative Properties Company Topical antimicrobial microemulsions with fluorescent materials
CN113164790A (en) * 2018-11-30 2021-07-23 3M创新有限公司 Topical antimicrobial microemulsions
KR20210151187A (en) * 2019-04-11 2021-12-13 알.피.쉐러 테크놀러지즈 엘엘씨 Formulations for Oral Delivery of Impermeable Proteins, Peptides and Small Molecules

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (en) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microemulsions
EP0387647A2 (en) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH High-dispersion pharmaceutical composition
WO1993002664A1 (en) * 1991-07-26 1993-02-18 Smithkline Beecham Corporation W/o microemulsions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110606A (en) * 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (en) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microemulsions
EP0387647A2 (en) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH High-dispersion pharmaceutical composition
WO1993002664A1 (en) * 1991-07-26 1993-02-18 Smithkline Beecham Corporation W/o microemulsions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9419003A1 *

Also Published As

Publication number Publication date
WO1994019003A1 (en) 1994-09-01
JPH08507078A (en) 1996-07-30
EP0684834A1 (en) 1995-12-06

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Legal Events

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