EP0610359A1 - Verfahren zur einrichtung fetaler stammzellen von mütterlichem blut - Google Patents

Verfahren zur einrichtung fetaler stammzellen von mütterlichem blut

Info

Publication number
EP0610359A1
EP0610359A1 EP92922837A EP92922837A EP0610359A1 EP 0610359 A1 EP0610359 A1 EP 0610359A1 EP 92922837 A EP92922837 A EP 92922837A EP 92922837 A EP92922837 A EP 92922837A EP 0610359 A1 EP0610359 A1 EP 0610359A1
Authority
EP
European Patent Office
Prior art keywords
cells
fetal
ceus
hgand
maternal blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92922837A
Other languages
English (en)
French (fr)
Inventor
Sheryl Williams
Ronald J. Berenson
Shelly Heimfeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CellPro Inc
Original Assignee
CellPro Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CellPro Inc filed Critical CellPro Inc
Publication of EP0610359A1 publication Critical patent/EP0610359A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0641—Erythrocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/14—Erythropoietin [EPO]
EP92922837A 1991-10-23 1992-10-22 Verfahren zur einrichtung fetaler stammzellen von mütterlichem blut Withdrawn EP0610359A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78214891A 1991-10-23 1991-10-23
US782148 1991-10-23
PCT/US1992/009024 WO1993008269A1 (en) 1991-10-23 1992-10-22 A method for enriching fetal progenitor cells from maternal blood

Publications (1)

Publication Number Publication Date
EP0610359A1 true EP0610359A1 (de) 1994-08-17

Family

ID=25125136

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92922837A Withdrawn EP0610359A1 (de) 1991-10-23 1992-10-22 Verfahren zur einrichtung fetaler stammzellen von mütterlichem blut

Country Status (4)

Country Link
EP (1) EP0610359A1 (de)
JP (1) JPH07500499A (de)
CA (1) CA2122138A1 (de)
WO (1) WO1993008269A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6773994A (en) * 1993-04-23 1994-11-21 Cellpro, Incorporated Methods for enriching fetal progenitor cells from maternal blood
US5580724A (en) * 1994-03-25 1996-12-03 Board Of Regents, The University Of Texas System Differential expansion of fetal stem cells in maternal circulation for use in prenatal genetic analysis
CA2183657A1 (en) * 1994-03-29 1995-10-05 Karen Pavelka Culture and isolation of fetal cells from maternal peripheral blood
US5840502A (en) * 1994-08-31 1998-11-24 Activated Cell Therapy, Inc. Methods for enriching specific cell-types by density gradient centrifugation
US5663051A (en) * 1994-08-31 1997-09-02 Activated Cell Therapy, Inc. Separation apparatus and method
US5648223A (en) * 1994-08-31 1997-07-15 Activated Cell Therapy, Inc. Methods for enriching breast tumor cells
US5646004A (en) * 1994-08-31 1997-07-08 Activated Cell Therapy, Inc. Methods for enriching fetal cells from maternal body fluids
GB0009179D0 (en) * 2000-04-13 2000-05-31 Imp College Innovations Ltd Non-invasive prenatal diagnosis
JP2010029178A (ja) * 2008-07-01 2010-02-12 Osaka Univ 細胞ピッキングシステム、スクリーニング方法および哺乳類細胞を取得する方法
CN106119189B (zh) * 2016-07-11 2020-04-10 山东亚大药业有限公司 胎儿有核红细胞的分离纯化方法及试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3044015C2 (de) * 1980-11-22 1984-03-29 Uwe Dr.med. 5223 Harscheid Claussen Verfahren und Einrichtung zur Präparation von in Teilung vorliegenden Zellen für die Chromosomenanalyse
JP2935741B2 (ja) * 1988-12-06 1999-08-16 フリンダーズ・テクノロジーズ・プラプライアテリー・リミテッド 出生前診断を可能にする母体血液からの胎児細胞の分離
DK0412700T3 (da) * 1989-08-03 1998-04-06 Univ California Fremgangsmåde til isolering af føtale cytrophoblastceller
JPH05501612A (ja) * 1989-11-13 1993-03-25 チルドレンズ・メデイカル・センター・コーポレーシヨン 胎児ｄｎａ単離および検出のための非侵入性方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9308269A1 *

Also Published As

Publication number Publication date
CA2122138A1 (en) 1993-04-29
WO1993008269A1 (en) 1993-04-29
JPH07500499A (ja) 1995-01-19

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19970621