EA201100618A1 - Противоопухолевое средство, способ его получения и способ его стабилизации - Google Patents

Противоопухолевое средство, способ его получения и способ его стабилизации

Info

Publication number
EA201100618A1
EA201100618A1 EA201100618A EA201100618A EA201100618A1 EA 201100618 A1 EA201100618 A1 EA 201100618A1 EA 201100618 A EA201100618 A EA 201100618A EA 201100618 A EA201100618 A EA 201100618A EA 201100618 A1 EA201100618 A1 EA 201100618A1
Authority
EA
Eurasian Patent Office
Prior art keywords
stabilization
preparation
methods
aqueous solution
tumor means
Prior art date
Application number
EA201100618A
Other languages
English (en)
Other versions
EA015680B1 (ru
Inventor
Олег Сергеевич Сокирко
Илима Илиодоровна Волченскова
Надежда Николаевна Майданевич
Original Assignee
Олег Сергеевич Сокирко
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from UAA200906849A external-priority patent/UA90233C2/ru
Application filed by Олег Сергеевич Сокирко filed Critical Олег Сергеевич Сокирко
Publication of EA015680B1 publication Critical patent/EA015680B1/ru
Publication of EA201100618A1 publication Critical patent/EA201100618A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение относится к медицине, а именно к противоопухолевым средствам на основе водного раствора соединений платины, способам получения указанных средств и к способам их стабилизации. Способ стабилизации противоопухолевых средств на основе водного раствора соединения платины осуществляют путем использования смеси основания фторурацила с урацилом и мочевиной, а также за счет использования раствора со сниженной концентрацией протонов.
EA201100618A 2008-12-22 2009-11-23 Противоопухолевое средство, способ его получения и способ его стабилизации EA201100618A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
UA200814666 2008-12-22
UAA200906849A UA90233C2 (ru) 2009-06-30 2009-06-30 Способ стабилизации противоопухолевых средств на основе водного раствора соединения платины с дезоксирибонуклеиновой кислотой
PCT/UA2009/000058 WO2010074662A1 (ru) 2008-12-22 2009-11-23 Противоопухолевое средство, способ его получения и способ его стабилизации

Publications (2)

Publication Number Publication Date
EA015680B1 EA015680B1 (ru) 2011-10-31
EA201100618A1 true EA201100618A1 (ru) 2011-10-31

Family

ID=42288021

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201100618A EA201100618A1 (ru) 2008-12-22 2009-11-23 Противоопухолевое средство, способ его получения и способ его стабилизации

Country Status (8)

Country Link
CN (1) CN102227222B (ru)
BG (1) BG66625B1 (ru)
BR (1) BRPI0923273A2 (ru)
EA (1) EA201100618A1 (ru)
IL (1) IL213446A (ru)
PL (1) PL219734B1 (ru)
TR (1) TR201104008T1 (ru)
WO (1) WO2010074662A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102784098A (zh) * 2011-05-20 2012-11-21 湖南省湘中制药有限公司 丙戊酸镁注射液及其制备工艺
CN104937096B (zh) * 2013-01-04 2019-11-05 德克萨斯系统大学董事会 包含柠檬酸的组合物及其应用
CN104027301B (zh) * 2013-03-05 2017-05-10 肖云彩 一种奥拉西坦组合物注射液
RU2667128C2 (ru) 2016-12-29 2018-09-14 Герман Петрович Беккер Композиция для приготовления противоопухолевого средства и способ приготовления противоопухолевого средства на ее основе

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5534513A (en) * 1991-09-05 1996-07-09 Taiho Pharmaceutical Company, Ltd. Antitumor potentiator and antitumor composition
UA70456A (en) * 2003-09-23 2004-10-15 Serhii Oleksandrovych Shalimov Dosage form of infusional antineoplastic drug and dosage form of infusional antineoplastic drug and method for its production method for its production
UA70455A (en) * 2003-09-23 2004-10-15 Serhii Oleksandrovych Shalimov Antineoplastic platinum drug for topical treatmentantineoplastic platinum drug for topical treatment of oropharyngeal cancer and method for its usage of oropharyngeal cancer and method for its usage

Also Published As

Publication number Publication date
EA015680B1 (ru) 2011-10-31
BG66625B1 (bg) 2017-12-15
CN102227222A (zh) 2011-10-26
TR201104008T1 (tr) 2011-10-21
IL213446A0 (en) 2011-07-31
IL213446A (en) 2013-11-28
WO2010074662A1 (ru) 2010-07-01
BRPI0923273A2 (pt) 2014-01-28
CN102227222B (zh) 2012-11-21
PL219734B1 (pl) 2015-07-31
PL394863A1 (pl) 2011-09-26
BG110926A (bg) 2011-10-31

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU

NF4A Restoration of lapsed right to a eurasian patent

Designated state(s): AM AZ BY KZ KG MD TJ TM RU

PC4A Registration of transfer of a eurasian patent by assignment
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU