EA200702386A1 - SOLID PHARMACEUTICAL COMPOSITION FOR LONG-TERM EXEMPTION OF 1- (2,3,4-TRIMETOXIBENZYL) PIPERAZINE AND METHOD FOR ITS PREPARATION - Google Patents

SOLID PHARMACEUTICAL COMPOSITION FOR LONG-TERM EXEMPTION OF 1- (2,3,4-TRIMETOXIBENZYL) PIPERAZINE AND METHOD FOR ITS PREPARATION

Info

Publication number
EA200702386A1
EA200702386A1 EA200702386A EA200702386A EA200702386A1 EA 200702386 A1 EA200702386 A1 EA 200702386A1 EA 200702386 A EA200702386 A EA 200702386A EA 200702386 A EA200702386 A EA 200702386A EA 200702386 A1 EA200702386 A1 EA 200702386A1
Authority
EA
Eurasian Patent Office
Prior art keywords
piperazine
pharmaceutical composition
solid pharmaceutical
trimetoxibenzyl
exemption
Prior art date
Application number
EA200702386A
Other languages
Russian (ru)
Other versions
EA013645B1 (en
Inventor
Жером Бессе
Original Assignee
Ле Лаборатуар Сервье
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ле Лаборатуар Сервье filed Critical Ле Лаборатуар Сервье
Publication of EA200702386A1 publication Critical patent/EA200702386A1/en
Publication of EA013645B1 publication Critical patent/EA013645B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Abstract

Твердая фармацевтическая композиция продолжительного высвобождения, которая включает активный ингредиент 1-(2,3,4-триметоксибензил)пиперазин или фармацевтически приемлемую соль 1-(2,3,4-триметоксибензил)пиперазина, в комбинации по крайней мере с одним полиэтиленоксидом и по крайней мере одним смазывающим агентом и одним или более фармацевтически приемлемыми наполнителями.A sustained release solid pharmaceutical composition that includes the active ingredient 1- (2,3,4-trimethoxybenzyl) piperazine or the pharmaceutically acceptable salt of 1- (2,3,4-trimethoxybenzyl) piperazine, in combination with at least one polyethylene oxide and at least at least one lubricating agent and one or more pharmaceutically acceptable excipients.

EA200702386A 2005-05-18 2006-02-13 Sustained release solid pharmaceutical composition of 1-(2,3,4-trimethoxybenzyl)piperazine and a method for the preparation thereof EA013645B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0504997A FR2885807B1 (en) 2005-05-18 2005-05-18 SOLID PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE OF 1- (2,3,4-TRIMETHOXYBENZYL) PIPERAZINE, AND PREPARATION METHOD
PCT/FR2006/050128 WO2006123073A1 (en) 2005-05-18 2006-02-13 Sustained release solid pharmaceutical composition of 1-(2,3,4-trimethoxybenzyl)piperazine and a method for the preparation thereof

Publications (2)

Publication Number Publication Date
EA200702386A1 true EA200702386A1 (en) 2008-04-28
EA013645B1 EA013645B1 (en) 2010-06-30

Family

ID=35583424

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200702386A EA013645B1 (en) 2005-05-18 2006-02-13 Sustained release solid pharmaceutical composition of 1-(2,3,4-trimethoxybenzyl)piperazine and a method for the preparation thereof

Country Status (5)

Country Link
EP (1) EP1881831A1 (en)
EA (1) EA013645B1 (en)
FR (1) FR2885807B1 (en)
UA (1) UA89408C2 (en)
WO (1) WO2006123073A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009066315A2 (en) * 2007-08-08 2009-05-28 Usv Limited Sustained release compositions of trimetazidine and process for preparation thereof
EP2200591A2 (en) * 2007-09-11 2010-06-30 Ranbaxy Laboratories Limited Controlled release pharmaceutical dosage forms of trimetazidine
JP2012515757A (en) * 2009-01-20 2012-07-12 マイクロ ラブス リミテッド Trimetazidine controlled release solid pharmaceutical composition and method for producing the same
TR201001902A2 (en) * 2010-03-12 2011-04-21 Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. Trimetazidine tablets with extended release
US20110274751A1 (en) * 2010-05-04 2011-11-10 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Trimetazidine formulation with different release profiles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717687B1 (en) * 1994-03-24 1996-06-14 Adir Pharmaceutical compositions for the sustained release of trimetazidine after oral administration.
FR2802424B1 (en) * 1999-12-17 2002-02-15 Adir MATRIX TABLET FOR THE EXTENDED RELEASE OF TRIMETAZIDINE AFTER ORAL ADMINISTRATION
ATE442852T1 (en) * 2000-10-05 2009-10-15 Usv Ltd DELAYED-RELEASE MEDICINAL COMPRISING TRIMETAZIDINE AND METHOD FOR THE PRODUCTION
FR2818549B1 (en) * 2000-12-26 2003-02-07 Servier Lab SOLID THERMOFORMABLE PHARMACEUTICAL COMPOSITION FOR THE CONTROLLED RELEASE OF TRIMETAZIDINE
AU2002356425A1 (en) * 2001-11-21 2003-06-10 Themis Laboratories Private Limited A process for manufacture of a sustained release composition containing microbe

Also Published As

Publication number Publication date
FR2885807A1 (en) 2006-11-24
FR2885807B1 (en) 2008-05-16
WO2006123073A1 (en) 2006-11-23
EA013645B1 (en) 2010-06-30
UA89408C2 (en) 2010-01-25
EP1881831A1 (en) 2008-01-30

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU