EA200000087A1 - Повышение эффективности терапии гиперпролиферативных состояний с помощью антиоксиданта - Google Patents
Повышение эффективности терапии гиперпролиферативных состояний с помощью антиоксидантаInfo
- Publication number
- EA200000087A1 EA200000087A1 EA200000087A EA200000087A EA200000087A1 EA 200000087 A1 EA200000087 A1 EA 200000087A1 EA 200000087 A EA200000087 A EA 200000087A EA 200000087 A EA200000087 A EA 200000087A EA 200000087 A1 EA200000087 A1 EA 200000087A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- antioxidant
- efficiency
- help
- antitumor agent
- hyperproliferative state
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
Способ усиления цитотоксической активности противоопухолевых лекарственных средств, включающий введение эффективного количества противоопухолевого лекарства хозяину, проявляющему аномальную клеточную пролиферацию, в сочетании с антиоксидантом в количестве, эффективно увеличивающем цитотоксичность. Изобретение также включает способ понижения токсичности противоопухолевого средства или увеличения терапевтического индекса противоопухолевого средства, применяемого для лечения плотной опухоли аномально пролиферирующих клеток, включая введение антиоксиданта до, одновременно или после обработки противоопухолевым средством.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88665397A | 1997-07-01 | 1997-07-01 | |
US96749297A | 1997-11-11 | 1997-11-11 | |
PCT/US1998/013750 WO1999001118A2 (en) | 1997-07-01 | 1998-07-01 | Antioxidant enhancement of therapy for hyperproliferative conditions |
Publications (1)
Publication Number | Publication Date |
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EA200000087A1 true EA200000087A1 (ru) | 2000-08-28 |
Family
ID=27128808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200000087A EA200000087A1 (ru) | 1997-07-01 | 1998-07-01 | Повышение эффективности терапии гиперпролиферативных состояний с помощью антиоксиданта |
Country Status (9)
Country | Link |
---|---|
US (1) | US7071158B2 (ru) |
EP (1) | EP1019034A2 (ru) |
JP (1) | JP2002511878A (ru) |
KR (1) | KR20010020611A (ru) |
CN (1) | CN1261803A (ru) |
AU (1) | AU8282798A (ru) |
CA (1) | CA2294247C (ru) |
EA (1) | EA200000087A1 (ru) |
WO (1) | WO1999001118A2 (ru) |
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CN1110139A (zh) * | 1994-04-15 | 1995-10-18 | 中国医学科学院医药生物技术研究所 | 丹酚酸a用于治疗肿瘤新用途 |
JPH07328425A (ja) | 1994-06-03 | 1995-12-19 | Toshiba Corp | プラズマ化学反応装置 |
JP3064815B2 (ja) * | 1994-07-28 | 2000-07-12 | 味の素株式会社 | ミエローマ系腫瘍抗癌剤 |
EP0799243A4 (en) | 1994-11-28 | 1998-08-19 | Wistar Inst | p53 PROTEINS WITH CHANGED TETRAMERIZATION DOMAINS |
US5792787A (en) * | 1995-06-07 | 1998-08-11 | Emory University | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
FR2738817B1 (fr) | 1995-09-14 | 1997-10-17 | Adir | Nouveaux acides et esters 2,2-dimethyl-omega-phenoxy alcanoiques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
WO1997015546A1 (fr) | 1995-10-26 | 1997-05-01 | Nippon Shinyaku Co., Ltd. | Derives d'acide carboxylique et compositions pharmaceutiques |
US5608095A (en) * | 1996-04-30 | 1997-03-04 | Hoechst Marion Roussel, Inc. | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents |
US5728534A (en) * | 1996-07-19 | 1998-03-17 | New England Medical Center Hospitals, Inc. | Methods for identifying cardiovascular therapeutic agents |
CN1275596C (zh) * | 1997-05-14 | 2006-09-20 | 阿特罗吉尼克斯公司 | 普罗布考单酯在制备用于治疗心血管疾病和炎性疾病的药物中的应用 |
-
1998
- 1998-07-01 CN CN98806719A patent/CN1261803A/zh active Pending
- 1998-07-01 EP EP98933078A patent/EP1019034A2/en not_active Withdrawn
- 1998-07-01 CA CA002294247A patent/CA2294247C/en not_active Expired - Fee Related
- 1998-07-01 KR KR1019997012630A patent/KR20010020611A/ko not_active Application Discontinuation
- 1998-07-01 AU AU82827/98A patent/AU8282798A/en not_active Abandoned
- 1998-07-01 WO PCT/US1998/013750 patent/WO1999001118A2/en not_active Application Discontinuation
- 1998-07-01 EA EA200000087A patent/EA200000087A1/ru unknown
- 1998-07-01 JP JP50736099A patent/JP2002511878A/ja active Pending
-
2001
- 2001-02-07 US US09/779,086 patent/US7071158B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1999001118A3 (en) | 1999-04-22 |
AU8282798A (en) | 1999-01-25 |
KR20010020611A (ko) | 2001-03-15 |
WO1999001118A9 (en) | 1999-05-20 |
CA2294247C (en) | 2004-10-26 |
EP1019034A2 (en) | 2000-07-19 |
US20010049349A1 (en) | 2001-12-06 |
JP2002511878A (ja) | 2002-04-16 |
WO1999001118A2 (en) | 1999-01-14 |
CA2294247A1 (en) | 1999-01-14 |
CN1261803A (zh) | 2000-08-02 |
US7071158B2 (en) | 2006-07-04 |
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