EA002179B1 - Method for the treating diabetes mellitus - Google Patents

Abstract

1. A method for the treatment of diabetes mellitus consisting in the exposure of an organism to the magnetic field during a definite time period, said method being characterized in that the exposure is applied to a foot by the pulse magnetic field. 2. The method of claim 1, characterized in that the cure is administrated on the average in 3 to 10 sessions.] 3. The method of claims 1-2, characterized in that the magnetic field induction is 10 -50 mT. 4. The method of claims 1-3, characterized in that the pulse frequency of the magnetic field is 0.1-20 Hz, the pulse duration is 45-55 msec, the oscillation frequency in pulses is 80-150 Hz. 5. The method of claims 1-3, characterized in that the exposure to the magnetic field is administrated with the buildup of the magnetic field intensity during further cure sessions. 6. The method of claims 1-5, characterized in that the sessions are administered with the extension of the duration of the exposure to the magnetic field. 7. The method of claims 1-6, characterized in that at first 3-4 sessions with 80% magnetic field intensity are administrated, and thereafter sessions with 100% magnetic field intensity are administrated. 8. The method of claims 1-7, characterized in that the sessions are administrated within 15-30 min. 9. The method of claims 1-8, characterized in that the exposure to the magnetic field is combined with effecting the acoupuncture points of the organism in the foot region. 10. The method of claims 1-9, characterized in that the exposure to the magnetic field is administered to the region of the pancreas projection on the foot. 11. The method of claims 1-10, characterized in that the exposure to the magnetic field is combined with the medicament treatment. 12. The method of claims 1-11, characterized in that an additional exposure to the magnetic field is administered to the leg from the foot to the knee joint. 13. A device for the treatment of the diabetes mellitus comprising a pulse former with a controller, connecting wires and an inductor, characterized in that the inductor includes at least one radiator of the magnetic field that is located in the pad for the foot. 14. The device of claims 1-13, characterized in that it is provided with additional lateral radiators of the magnetic field for the exposure to the leg from the foot to the knee joint.

Description

The present invention relates to medicine, in particular, to a method for the treatment of diabetes mellitus using a pulsed low-frequency magnetic field. The invention can be used to treat concomitant diseases and complications of diabetes mellitus, including diabetic foot syndrome.

According to WHO, about 6% of the world's population suffers from diabetes. Moreover, in recent decades there has been a steady increase in this disease among the population. In a screening study of 3223 patients with diabetes mellitus, diabetic foot syndrome was detected in 330 (10.2%) of them.

Known methods for local therapeutic effects on the human body of a magnetic field of high-frequency electromagnetic waves that cause a thermal effect (1). Such methods are widely used in practice in physiotherapy rooms, however, they mainly use the heating function, and in some cases they may be contraindicated.

From the patent of the Russian Federation No. 21553316 ("Integrated device for acupressure", author: Zaporozhtsev V.N.), a method of influencing the foot is known. The method consists in heating the foot at bioactive points of a special sole arranged in a specific sequence. The device has a heating element and contains two electrically conductive plates placed in the sole with holes that are located in a topographic order according to the scheme of bioactive points for thermal exposure.

From the patent of the Russian Federation No. 2150262 ("Device for pulsed high-frequency thermal exposure of foot acupressure", author: VN Zaporozhtsev) also known a method of pulsed high-frequency thermal exposure of foot acupressure. The method consists in heating the foot at bioactive points of a special sole arranged in a specific sequence. After the formation, the pulses adjusted in duration and height are fed to the massage element containing the heater, providing a pulsed high-frequency thermal effect on the reflexogenic zones to restore impaired functions. The device contains a sole with perforations placed according to the corresponding scheme, a heating element and a power supply.

The purpose of these methods is to stimulate the autonomic nervous system, increase arterial circulation, regulate tissue nutrition and the activity of the endocrine glands, reduce pain, reduce nervous and muscle tension. The use of these methods for the treatment of diabetes is unknown.

The closest solution according to the present invention can serve as a patent.

US No. 5803896. According to this method, a magnet is placed in the patient’s left auricle with a patch located in the area of the projection of the pancreas, the second magnet is placed in the other auricle at the projection point of the thalamus. In total, several magnets can be placed in both the right and left auricles. The device has a magnetic field induction of approximately 10,014,000 gauss (0.01-1.4 T). It is placed in the auricle for 24 hours. The treatment is accompanied by the introduction of insulin, which helps to stabilize blood sugar in a patient with diabetes. However, this method of treatment has several disadvantages. Firstly, the placement of magnets in the auricles can cause inconvenience to the patient, since they are there for 24 hours. Secondly, a direct effect is performed in the area of the brain, which can have an adverse effect on the patient. Thirdly, there is no certainty that it is the effect of magnets in the auricle that improves the patient's condition, since treatment is accompanied by the direct administration of insulin.

The objective of the present invention is to increase the effectiveness of the treatment of diabetes and eliminate the disadvantages of the closest solutions according to this invention.

A method of treating diabetes according to the present invention is to expose the body to a magnetic field for a certain period of time. Unlike other methods of treating diabetes mellitus, the effect is carried out on the foot by a pulsating low-frequency magnetic field. An average of 8-10 sessions are prescribed per treatment course. Magnetic field induction is 10-50 mT, the magnetic field pulse frequency is 0.120 Hz, the pulse duration is 45-55 ms, the pulse frequency is 80-150 Hz. Exposure to a magnetic field is carried out with increasing magnetic field strength in subsequent sessions. Sessions are carried out with increasing duration of exposure to the magnetic field. The first sessions (3-4) are carried out for 15-30 minutes at 80% magnetic field strength, and then sessions are conducted for 30 minutes at 100% magnetic field strength. In case of excessive heating of the feet, which worries the patient, the exposure parameters should be reduced to the initial ones. The influence of a magnetic field is combined with the impact on the acupuncture points of the body in the foot area. A special lining is placed under the foot, having a shape close to the shape of the footprint, in which magnetic inductors are integrated. Signals generating magnetic field pulses in the projection area of the pancreas on the foot in order to stimulate its functional activity are fed to it through wires. Exposure to a magnetic field is combined with drug treatment, in particular, with the introduction of various sugar-lowering drugs to increase their effectiveness. An additional magnetic field is also applied to the leg from the foot to the knee joint. For this, additional magnetic inductors are used.

Indications for assigning exposure to a magnetic field on the Diabspock apparatus are as follows.

1. Manifestations of diabetic distal polyneuropathy with severe pain and impaired sensitivity.

2. The manifestation of diabetic angiopathy without a pronounced violation of the main blood flow.

3. Mixed forms of foot damage in diabetes.

4. Osteopenia or osteoporosis in diabetic foot syndrome.

Exposure to a magnetic field (except for general contraindications) is not shown in the presence of trophic ulcers of the extremities, the appearance of dry gangrene, pyoderma or other skin lesions with a violation of its integrity, as well as with decompensation of diabetes mellitus.

Exposure to the magnetic field is carried out in three main directions:

1. the impact on the projection area of the pancreas in order to stimulate its functional activity,

2. the general physiotherapeutic effect to influence the reactivity of the body, stimulate the activity of various organs and systems, to increase the effectiveness of various sugar-lowering drugs,

3. the use of physical factors to treat concomitant diseases and complications of diabetes mellitus (DM), including diabetic foot syndrome (SDS).

In contrast to the previously claimed solutions according to the present invention use the device (apparatus "Diabspok"). comprising a magnetic field pulse shaper with a regulator, connecting wires and an inductor, which consists of at least one magnetic field emitter located in the lining under the foot of the foot. The device is made in the form of specific electromagnetic inductors and a case electronic unit connected by electrical cords through connectors to each other and to the electrical network.

The electronic unit of the Diabspock apparatus includes a power source, a generator of special signals for inductors and a microprocessor programmer. It provides a temporary mode of operation, signals the operation of inductors and an electronic unit. A lining is placed under the foot of the foot, and additional lateral sources of magnetic field are placed on the side of the foot to influence the foot from the foot to the knee joint.

Example 1

One example of physiotherapeutic treatment for CDS is the use of the Diabspock apparatus for exposure to a magnetic field. The authors studied the effects of a magnetic field using this apparatus in 45 patients with diabetes complicated by SDS. The clinical characteristics of patients are presented in table. 6. The treatment course consisted of 3 sessions of 20 minutes. With the inclusion of 80% power and 5 sessions of 30 minutes. With the inclusion of 100% power on each limb. The control group consisted of 10 people, comparable by sex, age, duration of diabetes and the severity of diabetes.

Table 1. Clinical characteristics of patients included in the study.

Options Magnetic field exposure group Control group N 45 twenty Age (years) 33.6 ± 3.12 29.7 ± 5.17 Duration SD (in years) 8.7 ± 1.40 7.6 ± 2.10 IL1 _S 9.3 ± 0.87 9.6 ± 0.92

To assess the effectiveness of exposure to a magnetic field before and after sessions, the temperature sensitivity was determined using a Τίρ-Tegsh analyzer, a graduated tuning fork, and a diagnostic 10-gram monofilament; the nerve impulse conduction rate was assessed using electroneurography and the turbulent blood flow velocity on the dorsal artery and hind-foot artery of the feet (using ultrasound dopleplay). The results of the study for each method for determining the degree of sensitivity violation were evaluated using a 3-point system (0-norm, 1-border state, 2-expressed violations). At the same time, the dynamics of the ECG and blood pressure profile were evaluated. A daily survey of patients was conducted to identify unwanted side effects, tolerance features of magnetotherapy, the degree of convenience of the treatment session.

The treatment results demonstrated the effectiveness of the course of exposure to the magnetic field: positive changes in sensitivity, an increase in the speed of the nerve impulse and peripheral blood flow were noted (Table 2).

Table 2. Dynamics of fixed indicators before and after the course of exposure to a magnetic field

The investigated parameters Before treatment After treatment Sensitivity Temperature 1.8 ± 0.1 1.4 ± 0.1 Vibrating 2.1 ± 0.4 1.6 ± 0.5 Tactile 2.3 ± 0.5 1.8 ± 0.7 The speed of the nerve impulse (m / s) 34.1 ± 1.3 51.4 ± 1.4

At the same time, no negative changes were detected in the general well-being of patients, ECG, or blood pressure profile.

According to the subjective assessment of patients obtained on the basis of a daily survey, the course of treatment was effective, since almost all patients noted a decrease in limb pain, seizures and paresthesia, “warming” of the extremities, an increase in muscle activity and strength (Table 3). When analyzing the dependence of the dynamics of indicators of neurometry on the type of diabetes, no significant changes were found.

Table 3. The results of the course of exposure to the magnetic field according to the subjective assessment of patients

Options Assessment before treatment In points after treatment The severity of pain 2.8 ± 0.1 0.9 ± 0.1 Convulsive syndrome 2.4 ± 0.2 1.6 ± 0.3 Chilliness of the feet 2.7 ± 0.15 0.2 ± 0.1 Paresthesia 2.1 ± 0.3 1.6 ± 0.3

When using the Diabspock apparatus in the case of a predominant lesion of the foot nerves (neuropathic form of SDS), a positive effect was also obtained, which is confirmed by a decrease in paresthesia, pain, seizures, tendencies to normalize all tested types of sensitivity and positive dynamics of neurometry indicators.

The ischemic form of SDS is also amenable to correction using this apparatus (the severity of “coldness” of the feet and “cooling” of the extremities decreases, the speed of turbulent blood flow in the arteries of the feet increases).

According to research by numerous authors, manifestations of osteopenia or osteoporosis are a pathogenetic component of SDS. At the same time, trophic exposure to a magnetic field, confirmed by studying bone lesions of a different etiology, suggests that with bone deformities, the development of osteopenia and osteoporosis, repeated courses of exposure to a magnetic field give a positive effect.

Thus, exposure to a magnetic field is an effective alternative method of physiotherapeutic treatment for SDS. Our results indicate the possibility of assigning exposure to the Diabspock magnetic field for any form of foot damage.

Information sources

1. Handbook of physiotherapy (edited by VG Yasnogorodsky), M., Medicine, 1992, p. thirteen.

2. Grandfather II Complications of diabetes. - M., 1995., p. 24-43.

3. Integrated device for acupressure. - Patent VI No. 2155316, A 61 N / 15/00, 39/04, 39/06.

4. Device for pulsed high-frequency thermal effects of acupressure of the foot. - Patent VI No. 2150262, A 61 H 39/06, A 61 N 5/06, A 61 P 7/00.

5. A method for the treatment of diabetes. - Patent I8 No. 5,803,896.

Claims (13)

1. A method of treating diabetes mellitus, which consists in exposing the body to a magnetic field for a certain period of time, characterized in that the exposure is carried out on the foot by a pulsating magnetic field. 2. The method according to claim 1, characterized in that an average of 3-10 sessions are prescribed per treatment course. 3. The method according to claims 1 to 2, characterized in that the magnetic field induction is 10-50 mT. 4. The method according to claims 1 to 3, characterized in that the frequency of the magnetic field pulses is 0.1-20 Hz, the pulse duration is 45-55 ms, the generation frequency in pulses is 80-150 Hz. 5. The method according to claims 1 to 4, characterized in that the magnetic field is carried out with increasing magnetic field strength in subsequent sessions. 6. The method according to claims 1-5, characterized in that the sessions are carried out with increasing duration of exposure to a magnetic field. 7. The method according to claims 1 to 6, characterized in that at first they conduct 3-4 sessions at 80% magnetic field strength, and then carry out sessions at 1 00% magnetic field strength. 8. The method according to claims 1 to 7, characterized in that the sessions are carried out for 15-30 minutes 9. The method according to claims 1 to 8, characterized in that the magnetic field is combined with the action on the acupuncture points of the body in the foot area. 10. The method according to claims 1 to 9, characterized in that the magnetic field is applied to the projection area of the pancreas on the foot. 11. The method according to PP. 1-10, characterized in that the magnetic field is combined with drug treatment. 12. The method according to PP. 1 -11, characterized in that they carry out additional magnetic field effects on the leg from the foot to the knee joint. 13. A device for treating diabetes mellitus, comprising a magnetic field pulse shaper with a regulator, connecting wires and an inductor, characterized in that the inductor consists of at least one