DK39892D0 - PEPTIDE - Google Patents

PEPTIDE

Info

Publication number
DK39892D0
DK39892D0 DK92398A DK39892A DK39892D0 DK 39892 D0 DK39892 D0 DK 39892D0 DK 92398 A DK92398 A DK 92398A DK 39892 A DK39892 A DK 39892A DK 39892 D0 DK39892 D0 DK 39892D0
Authority
DK
Denmark
Prior art keywords
glp
pct
agonists
receptor
sec
Prior art date
Application number
DK92398A
Other languages
Danish (da)
Inventor
Bernard Thorens
Original Assignee
Bernard Thorens
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8093079&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK39892(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bernard Thorens filed Critical Bernard Thorens
Priority to DK92398A priority Critical patent/DK39892D0/en
Publication of DK39892D0 publication Critical patent/DK39892D0/en
Priority to AU37512/93A priority patent/AU3751293A/en
Priority to PCT/EP1993/000697 priority patent/WO1993019175A1/en
Priority to ES93906589T priority patent/ES2070801T1/en
Priority to EP93906589A priority patent/EP0586657B1/en
Priority to DE0586657T priority patent/DE586657T1/en
Priority to US08/142,439 priority patent/US5670360A/en
Priority to JP51628793A priority patent/JP3371379B2/en
Priority to AT93906589T priority patent/ATE184648T1/en
Priority to DE69326405T priority patent/DE69326405T2/en
Priority to GR950300031T priority patent/GR950300031T1/en
Priority to US08/869,477 priority patent/US5846747A/en
Priority to US08/935,317 priority patent/US6051689A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/605Glucagons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones

Abstract

PCT No. PCT/EP93/00697 Sec. 371 Date Nov. 24, 1993 Sec. 102(e) Date Nov. 24, 1993 PCT Filed Mar. 23, 1993 PCT Pub. No. WO93/19175 PCT Pub. Date Sep. 30, 1993The present invention relates to a recombinant glucagon like peptide-1 (GLP-1), to a DNA construct which comprises a DNA sequence encoding a GLP-1 receptor, to methods of screening for agonists of GLP-1 activity, and to the use of the GLP-1 receptor for screening for agonists of GLP-1 activity.
DK92398A 1992-03-25 1992-03-25 PEPTIDE DK39892D0 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DK92398A DK39892D0 (en) 1992-03-25 1992-03-25 PEPTIDE
DE69326405T DE69326405T2 (en) 1992-03-25 1993-03-23 Receptor for the glucagon-like peptide-1 (GLP-1)
AT93906589T ATE184648T1 (en) 1992-03-25 1993-03-23 RECEPTOR FOR GLUCAGONE-LIKE PEPTIDE-1 (GLP-1)
DE0586657T DE586657T1 (en) 1992-03-25 1993-03-23 Receptor for the glucagon-like peptide-1 (GLP-1).
PCT/EP1993/000697 WO1993019175A1 (en) 1992-03-25 1993-03-23 Receptor for the glucagon-like-peptide-1 (glp-1)
ES93906589T ES2070801T1 (en) 1992-03-25 1993-03-23 RECEPTOR FOR GLUCAGON-LIKE PEPTIDE-1 (GLP-1).
EP93906589A EP0586657B1 (en) 1992-03-25 1993-03-23 Receptor for the glucagon-like-peptide-1 (glp-1)
AU37512/93A AU3751293A (en) 1992-03-25 1993-03-23 Receptor for the glucagon-like-peptide-1 (GLP-1)
US08/142,439 US5670360A (en) 1992-03-25 1993-03-23 Mammalian receptors for glucagon-like-peptide-1 (GLP-1), corresponding DNA and recombinant expression systems, and screening assays for GLP-1 agonists and enhancers
JP51628793A JP3371379B2 (en) 1992-03-25 1993-03-23 Receptor for glucagon-like peptide-1 (GLP-1)
GR950300031T GR950300031T1 (en) 1992-03-25 1995-06-30 Receptor for the glucagon-like-peptide-1 (glp-1).
US08/869,477 US5846747A (en) 1992-03-25 1997-06-05 Method for detecting glucagon-like peptide-1 antagonists and agonists
US08/935,317 US6051689A (en) 1992-03-25 1997-09-22 Receptor for the glucagon-like-peptide (GLP-1)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK92398A DK39892D0 (en) 1992-03-25 1992-03-25 PEPTIDE

Publications (1)

Publication Number Publication Date
DK39892D0 true DK39892D0 (en) 1992-03-25

Family

ID=8093079

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92398A DK39892D0 (en) 1992-03-25 1992-03-25 PEPTIDE

Country Status (10)

Country Link
US (2) US5670360A (en)
EP (1) EP0586657B1 (en)
JP (1) JP3371379B2 (en)
AT (1) ATE184648T1 (en)
AU (1) AU3751293A (en)
DE (2) DE69326405T2 (en)
DK (1) DK39892D0 (en)
ES (1) ES2070801T1 (en)
GR (1) GR950300031T1 (en)
WO (1) WO1993019175A1 (en)

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US5614492A (en) * 1986-05-05 1997-03-25 The General Hospital Corporation Insulinotropic hormone GLP-1 (7-36) and uses thereof
US6849708B1 (en) 1986-05-05 2005-02-01 The General Hospital Corporation Insulinotropic hormone and uses thereof
US7138486B2 (en) 1986-05-05 2006-11-21 The General Hospital Corporation Insulinotropic hormone derivatives and uses thereof
US5846747A (en) * 1992-03-25 1998-12-08 Novo Nordisk A/S Method for detecting glucagon-like peptide-1 antagonists and agonists
DK39892D0 (en) * 1992-03-25 1992-03-25 Bernard Thorens PEPTIDE
SK155694A3 (en) * 1992-06-15 1995-05-10 Pfizer Glucagon-like peptide, insulinotropin derivatives, method of their preparation, pharmaceutical agent containing and using these matters
WO1994005789A1 (en) * 1992-08-28 1994-03-17 Zymogenetics, Inc. Glucagon receptors
US6284727B1 (en) 1993-04-07 2001-09-04 Scios, Inc. Prolonged delivery of peptides
CA2168448A1 (en) * 1993-08-09 1995-02-16 Michael P. Graziano Human glucagon-like 1 peptide receptor
GB9502830D0 (en) * 1995-02-14 1995-04-05 Ecole Polytech Regulation of polypeptide production in cells
DE69737561T2 (en) * 1996-12-13 2008-03-06 Nps Allelix Corp., Toronto CLONED GLUCAGON-SIMILAR PEPTIDE-2 RECEPTORS
US8592553B2 (en) 1996-12-13 2013-11-26 Nps Pharmaceuticals, Inc. Cloned glucagon-like peptide-2 receptors
WO2000007617A1 (en) 1998-07-31 2000-02-17 Novo Nordisk A/S Use of glp-1 and analogues for preventing type ii diabetes
JP2002528721A (en) * 1998-10-23 2002-09-03 グラクソ グループ リミテッド Assays for nuclear receptor ligands
JP2003525908A (en) 2000-03-08 2003-09-02 ノボ ノルディスク アクティーゼルスカブ Low serum lipids
US6448045B1 (en) * 2000-03-10 2002-09-10 The Regents Of The University Of California Inducing insulin gene expression in pancreas cells expressing recombinant PDX-1
US20020123071A1 (en) * 2000-12-04 2002-09-05 Knudsen Sanne Moller Method of identifying compounds capable of acting as agonists or antagonists of G-protein coupled receptors
US6642003B2 (en) 2001-08-02 2003-11-04 Cedars-Sinai Medical Center Human glucose-dependent insulin-secreting cell line
DE60230818D1 (en) 2001-09-24 2009-02-26 Imp Innovations Ltd PYY3-36 FOR REDUCING OR PREVENTING GREASE LUBRICITY
US6911324B2 (en) 2001-10-18 2005-06-28 The Regents Of The University Of California Induction of beta cell differentiation in human cells
EP1474163A2 (en) 2002-01-10 2004-11-10 Imperial College Innovations Limited Modification of feeding behavior
US7141240B2 (en) * 2002-03-12 2006-11-28 Cedars-Sinai Medical Center Glucose-dependent insulin-secreting cells transfected with a nucleotide sequence encoding GLP-1
DE60327771D1 (en) 2002-07-04 2009-07-09 Zealand Pharma As GLP-1 AND TREATMENT METHOD FOR DIABETES
EP1546200A2 (en) 2002-10-02 2005-06-29 Zealand Pharma A/S Stabilized exendin-4 compounds
US20040209803A1 (en) * 2002-12-19 2004-10-21 Alain Baron Compositions for the treatment and prevention of nephropathy
US7790681B2 (en) * 2002-12-17 2010-09-07 Amylin Pharmaceuticals, Inc. Treatment of cardiac arrhythmias with GLP-1 receptor ligands
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WO2004071393A2 (en) * 2003-02-13 2004-08-26 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with glucagon-like peptide 1 receptor (glp1r)
WO2005018536A2 (en) * 2003-05-23 2005-03-03 Human Genome Sciences, Inc. Agonist antibodies that specifically bind the glucagon like peptide-1 receptor
CN104826116A (en) 2003-11-20 2015-08-12 诺沃挪第克公司 Propylene glycol-containing peptide formulations which are optimal for production and for use in injection devices
EP1694356B1 (en) 2003-12-09 2011-02-16 Novo Nordisk A/S Regulation of food preference using glp-1 agonists
CN1950078A (en) 2004-06-11 2007-04-18 诺和诺德公司 Counteracting drug-induced obesity using glp-1 agonists
SG156683A1 (en) 2005-06-07 2009-11-26 Univ Rockefeller STIMULATION OF PANCREATIC β CELL PROLIFERATION
TWI428346B (en) 2006-12-13 2014-03-01 Imp Innovations Ltd Novel compounds and their effects on feeding behaviour
WO2009126709A1 (en) * 2008-04-09 2009-10-15 Transtech Pharma, Inc. Ligands for the glp-1 receptor and methods for discovery thereof
WO2010043566A2 (en) 2008-10-17 2010-04-22 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a glp-1 agonist
ES2855146T3 (en) 2009-11-13 2021-09-23 Sanofi Aventis Deutschland Pharmaceutical composition comprising a GLP-1 agonist, an insulin and methionine
US9707176B2 (en) 2009-11-13 2017-07-18 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist and methionine
WO2011123943A1 (en) 2010-04-09 2011-10-13 Mount Sinai Hospital Methods for treating disorders of the gastrointestinal tract using a glp-1 agonist
MX343360B (en) 2010-04-27 2016-11-03 Zealand Pharma As Peptide conjugates of glp-1 receptor agonists and gastrin and their use.
PT2611458T (en) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
RU2600440C3 (en) 2010-12-16 2021-12-10 Ново Нордиск А/С SOLID COMPOSITIONS CONTAINING GLP-1 AGONIST AND N- (8- (2-HYDROXYBENZOYL) AMINO) CAPRYLIC ACID SALT
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
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UA122767C2 (en) 2013-10-17 2021-01-06 Зіленд Фарма А/С Acylated glucagon analogues
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CN112957455A (en) 2014-01-09 2021-06-15 赛诺菲 Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives
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WO2015104311A1 (en) 2014-01-09 2015-07-16 Sanofi Stabilized glycerol free pharmaceutical formulations of insulin analogues and/or insulin derivatives
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TWI748945B (en) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 Treatment type 2 diabetes mellitus patients
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CA2997343A1 (en) 2015-10-07 2017-04-13 Cyprumed Gmbh Pharmaceutical formulations for the oral delivery of peptide drugs
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK39892D0 (en) * 1992-03-25 1992-03-25 Bernard Thorens PEPTIDE

Also Published As

Publication number Publication date
EP0586657A1 (en) 1994-03-16
DE69326405T2 (en) 2000-03-23
ATE184648T1 (en) 1999-10-15
DE586657T1 (en) 1996-01-18
AU3751293A (en) 1993-10-21
GR950300031T1 (en) 1995-06-30
ES2070801T1 (en) 1995-06-16
WO1993019175A1 (en) 1993-09-30
US6051689A (en) 2000-04-18
DE69326405D1 (en) 1999-10-21
EP0586657B1 (en) 1999-09-15
JPH06508765A (en) 1994-10-06
US5670360A (en) 1997-09-23
JP3371379B2 (en) 2003-01-27

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