DK347086D0 - Novel peptides - Google Patents

Novel peptides

Info

Publication number
DK347086D0
DK347086D0 DK347086A DK347086A DK347086D0 DK 347086 D0 DK347086 D0 DK 347086D0 DK 347086 A DK347086 A DK 347086A DK 347086 A DK347086 A DK 347086A DK 347086 D0 DK347086 D0 DK 347086D0
Authority
DK
Denmark
Prior art keywords
amino acid
solutions
insulin
asn
substituted
Prior art date
Application number
DK347086A
Other languages
English (en)
Inventor
Jan Markussen
Kjeld Norris
Liselotte Langkjaer
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8123250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK347086(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK347086A priority Critical patent/DK347086D0/da
Publication of DK347086D0 publication Critical patent/DK347086D0/da
Priority to ES87306405T priority patent/ES2061504T3/es
Priority to YU01353/87A priority patent/YU135387A/xx
Priority to US07/075,387 priority patent/US4946828A/en
Priority to FI873185A priority patent/FI873185A/fi
Priority to ZA875295A priority patent/ZA875295B/xx
Priority to DK376187A priority patent/DK160880C/da
Priority to EP87306405A priority patent/EP0254516B1/en
Priority to DD87305161A priority patent/DD273839A5/de
Priority to KR1019870007832A priority patent/KR880001701A/ko
Priority to CN198787104988A priority patent/CN87104988A/zh
Priority to IL83243A priority patent/IL83243A/xx
Priority to NZ221130A priority patent/NZ221130A/xx
Priority to PT85355A priority patent/PT85355B/pt
Priority to MYPI87001062A priority patent/MY102873A/en
Priority to DE2000175024 priority patent/DE10075024I1/de
Priority to AT87306405T priority patent/ATE99699T1/de
Priority to DE3788684T priority patent/DE3788684T2/de
Priority to NO873018A priority patent/NO170978C/no
Priority to AU75916/87A priority patent/AU612324B2/en
Priority to HU873343A priority patent/HU203371B/hu
Priority to JP62180168A priority patent/JPS6399096A/ja
Priority to US07/424,503 priority patent/US5008241A/en
Priority to NL300018C priority patent/NL300018I1/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK347086A 1985-03-12 1986-07-21 Novel peptides DK347086D0 (da)

Priority Applications (24)

Application Number Priority Date Filing Date Title
DK347086A DK347086D0 (da) 1986-07-21 1986-07-21 Novel peptides
AU75916/87A AU612324B2 (en) 1986-07-21 1987-07-20 Novel peptides and injectable solutions having prolonged insulin action
HU873343A HU203371B (en) 1986-07-21 1987-07-20 Process for producing new insulin derivatives and injection solutions comprising same
KR1019870007832A KR880001701A (ko) 1986-07-21 1987-07-20 신규한 펩티드
NZ221130A NZ221130A (en) 1986-07-21 1987-07-20 Insulin analogues with greater positive charge than human insulin at neutral ph
US07/075,387 US4946828A (en) 1985-03-12 1987-07-20 Novel insulin peptides
FI873185A FI873185A (fi) 1986-07-21 1987-07-20 Nya peptider.
ZA875295A ZA875295B (en) 1986-07-21 1987-07-20 Novel peptides
DK376187A DK160880C (da) 1986-07-21 1987-07-20 Insulinderivater samt injicerbare oploesninger indeholdende disse
EP87306405A EP0254516B1 (en) 1986-07-21 1987-07-20 Novel Peptides
DD87305161A DD273839A5 (de) 1986-07-21 1987-07-20 Verfahren zur herstellung neuer insulinderivate
ES87306405T ES2061504T3 (es) 1986-07-21 1987-07-20 Nuevos peptidos.
CN198787104988A CN87104988A (zh) 1986-07-21 1987-07-20 新的多肽
IL83243A IL83243A (en) 1986-07-21 1987-07-20 Insulin derivatives optionally having alterations in the a4, a17, a21, b13, b21 and b27 positions
YU01353/87A YU135387A (en) 1986-07-21 1987-07-20 Process for obtaining new peptides
PT85355A PT85355B (pt) 1986-07-21 1987-07-20 Processo para a preparacao de novos peptidos
MYPI87001062A MY102873A (en) 1986-07-21 1987-07-20 Novel peptides
DE2000175024 DE10075024I1 (de) 1986-07-21 1987-07-20 Peptide
AT87306405T ATE99699T1 (de) 1986-07-21 1987-07-20 Peptide.
DE3788684T DE3788684T2 (de) 1986-07-21 1987-07-20 Peptide.
NO873018A NO170978C (no) 1986-07-21 1987-07-20 Analogifremgangsmaate ved fremstilling av nye peptider
JP62180168A JPS6399096A (ja) 1986-07-21 1987-07-21 インシュリン誘導体
US07/424,503 US5008241A (en) 1985-03-12 1989-10-20 Novel insulin peptides
NL300018C NL300018I1 (nl) 1986-07-21 2000-09-15 Nieuwe peptiden.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK347086A DK347086D0 (da) 1986-07-21 1986-07-21 Novel peptides

Publications (1)

Publication Number Publication Date
DK347086D0 true DK347086D0 (da) 1986-07-21

Family

ID=8123250

Family Applications (1)

Application Number Title Priority Date Filing Date
DK347086A DK347086D0 (da) 1985-03-12 1986-07-21 Novel peptides

Country Status (20)

Country Link
EP (1) EP0254516B1 (da)
JP (1) JPS6399096A (da)
KR (1) KR880001701A (da)
CN (1) CN87104988A (da)
AT (1) ATE99699T1 (da)
AU (1) AU612324B2 (da)
DD (1) DD273839A5 (da)
DE (2) DE10075024I1 (da)
DK (1) DK347086D0 (da)
ES (1) ES2061504T3 (da)
FI (1) FI873185A (da)
HU (1) HU203371B (da)
IL (1) IL83243A (da)
MY (1) MY102873A (da)
NL (1) NL300018I1 (da)
NO (1) NO170978C (da)
NZ (1) NZ221130A (da)
PT (1) PT85355B (da)
YU (1) YU135387A (da)
ZA (1) ZA875295B (da)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10075034I1 (de) * 1987-02-25 2001-05-23 Novo Nordisk As Insulinderivate
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
KR900701842A (ko) * 1988-07-20 1990-12-04 헨리 브뢰늄 인간 인슐린 동족체와 그를 포함하는 제제
DE3827533A1 (de) * 1988-08-13 1990-02-15 Hoechst Ag Pharmazeutische zubereitung zur behandlung des diabetes mellitus
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
HUT56857A (en) * 1988-12-23 1991-10-28 Novo Nordisk As Human insulin analogues
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
US5514646A (en) * 1989-02-09 1996-05-07 Chance; Ronald E. Insulin analogs modified at position 29 of the B chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5474978A (en) * 1994-06-16 1995-12-12 Eli Lilly And Company Insulin analog formulations
US5693609A (en) * 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
US7316999B2 (en) 2000-06-02 2008-01-08 Novo Nordisk A/S Glucose dependent release of insulin from glucose sensing insulin derivatives
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
EP1448786B1 (en) 2001-11-19 2010-04-14 Novo Nordisk A/S Process for preparing insulin compounds
GB0206792D0 (en) 2002-03-22 2002-05-01 Leuven K U Res & Dev Normoglycemia
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
AU2004251810B2 (en) 2003-06-27 2010-03-04 Novo Nordisk A/S High moisture barrier container for medical liquid compositions
WO2005061222A1 (en) 2003-12-22 2005-07-07 Novo Nordisk A/S Transparent, flexible, impermeable plastic container for storage of pharmaceutical liquids
ATE550041T1 (de) 2004-01-21 2012-04-15 Novo Nordisk Healthcare Ag Transglutaminase-vermittelte konjugation von peptiden
DE102006031962A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
DE102006031955A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
WO2008049711A1 (en) 2006-10-27 2008-05-02 Novo Nordisk A/S Peptide extended insulins
JP5695909B2 (ja) 2008-01-09 2015-04-08 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 極度に遅延した時間作用プロファイルを有する新規なインスリン誘導体
CN102007143B (zh) 2008-01-09 2015-08-26 塞诺菲-安万特德国有限公司 具有超延迟时效特征的新型胰岛素衍生物
WO2009115469A1 (en) 2008-03-18 2009-09-24 Novo Nordisk A/S Protease stabilized, acylated insulin analogues
TWI451876B (zh) 2008-06-13 2014-09-11 Lilly Co Eli 聚乙二醇化之離脯胰島素化合物
JP5903269B2 (ja) 2008-08-07 2016-04-13 バイオコン リミテッド インスリン化合物の調製方法
RS56632B1 (sr) 2008-10-17 2018-03-30 Sanofi Aventis Deutschland Kombinacija insulina i glp-1-agonista
WO2011003820A1 (de) * 2009-07-06 2011-01-13 Sanofi-Aventis Deutschland Gmbh Hitze- und schüttelstabile insulinzubereitungen
PT3345593T (pt) 2009-11-13 2023-11-27 Sanofi Aventis Deutschland Composição farmacêutica compreendendo despro36exendina- 4(1-39)-lys6-nh2 e metionina
ES2855146T3 (es) 2009-11-13 2021-09-23 Sanofi Aventis Deutschland Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina
EP2460527A1 (en) 2010-01-21 2012-06-06 Sanofi Pharmaceutical composition for treating a metabolic syndrome
TW201141513A (en) 2010-04-14 2011-12-01 Sanofi Aventis Insulin-siRNA conjugates
HUE031181T2 (en) 2010-08-30 2017-06-28 Sanofi Aventis Deutschland Use of AVE0010 for the manufacture of a medicament for the treatment of type 2 diabetes
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
EP2548570A1 (en) 2011-07-19 2013-01-23 Sanofi Pharmaceutical composition for treating a metabolic syndrome
CN103917241A (zh) 2011-08-29 2014-07-09 赛诺菲-安万特德国有限公司 用于2型糖尿病患者中的血糖控制的药物组合
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
US9481721B2 (en) 2012-04-11 2016-11-01 Novo Nordisk A/S Insulin formulations
WO2015196174A1 (en) 2014-06-20 2015-12-23 Greene Howard E Infusion delivery devices and methods
JP6970615B2 (ja) 2014-12-12 2021-11-24 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング インスリングラルギン/リキシセナチド固定比処方
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療
CN115154591B (zh) 2016-12-16 2023-04-14 诺和诺德股份有限公司 含胰岛素的药物组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033127A1 (de) * 1980-09-03 1982-04-08 Hoechst Ag, 6000 Frankfurt Neue analoga des insulins
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat

Also Published As

Publication number Publication date
NO873018L (no) 1988-01-22
NO873018D0 (no) 1987-07-20
ES2061504T3 (es) 1994-12-16
IL83243A0 (en) 1987-12-31
HUT45271A (en) 1988-06-28
PT85355A (en) 1987-08-01
DE3788684T2 (de) 1994-05-19
NO170978B (no) 1992-09-28
NZ221130A (en) 1990-08-28
AU612324B2 (en) 1991-07-11
EP0254516A2 (en) 1988-01-27
NO170978C (no) 1993-01-06
HU203371B (en) 1991-07-29
CN87104988A (zh) 1988-03-02
FI873185A (fi) 1988-01-22
KR880001701A (ko) 1988-04-26
JPS6399096A (ja) 1988-04-30
PT85355B (pt) 1990-04-30
ZA875295B (en) 1988-01-21
EP0254516B1 (en) 1994-01-05
DE10075024I1 (de) 2000-11-09
YU135387A (en) 1988-10-31
EP0254516A3 (en) 1990-06-27
MY102873A (en) 1993-03-31
ATE99699T1 (de) 1994-01-15
FI873185A0 (fi) 1987-07-20
AU7591687A (en) 1988-01-28
IL83243A (en) 1993-01-14
DE3788684D1 (de) 1994-02-17
NL300018I1 (nl) 2000-11-01
DD273839A5 (de) 1989-11-29

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment