DK2029722T3 - Fremgangsmåde og system til celleproduktion - Google Patents

Fremgangsmåde og system til celleproduktion Download PDF

Info

Publication number
DK2029722T3
DK2029722T3 DK07777182.2T DK07777182T DK2029722T3 DK 2029722 T3 DK2029722 T3 DK 2029722T3 DK 07777182 T DK07777182 T DK 07777182T DK 2029722 T3 DK2029722 T3 DK 2029722T3
Authority
DK
Denmark
Prior art keywords
cell
growth chamber
base device
cells
cell growth
Prior art date
Application number
DK07777182.2T
Other languages
English (en)
Inventor
Robert J Wojciechowski
Darrell Paul Page
Michael John Gramer
Karl Patrick Bongers
Scott Thomas Waniger
Beverly Norris
Mark D Hirschel
Thiem Chan Duong Wong
Grant Adams
Martin Peder Crep
Original Assignee
Biovest Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovest Int Inc filed Critical Biovest Int Inc
Application granted granted Critical
Publication of DK2029722T3 publication Critical patent/DK2029722T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/20—Heat exchange systems, e.g. heat jackets or outer envelopes the heat transfer medium being a gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/38—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of metabolites or enzymes in the cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/20—Heating or cooling
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q3/00—Condition responsive control processes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/0009—Special features
    • F04B43/0054—Special features particularities of the flexible members
    • F04B43/0072—Special features particularities of the flexible members of tubular flexible members
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/08—Machines, pumps, or pumping installations having flexible working members having tubular flexible members
    • F04B43/09—Pumps having electric drive
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1253—Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing
    • F04B43/1292—Pumps specially adapted for several tubular flexible members

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Computer Hardware Design (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Thermal Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK07777182.2T 2006-05-22 2007-05-21 Fremgangsmåde og system til celleproduktion DK2029722T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80237606P 2006-05-22 2006-05-22
PCT/US2007/012042 WO2007139742A1 (en) 2006-05-22 2007-05-21 Method and system for the production of cells and cell products and applications thereof

Publications (1)

Publication Number Publication Date
DK2029722T3 true DK2029722T3 (da) 2020-01-02

Family

ID=38473943

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07777182.2T DK2029722T3 (da) 2006-05-22 2007-05-21 Fremgangsmåde og system til celleproduktion

Country Status (7)

Country Link
US (6) US8383397B2 (da)
EP (3) EP2404991A3 (da)
AT (1) ATE496987T1 (da)
DE (1) DE602007012238D1 (da)
DK (1) DK2029722T3 (da)
ES (1) ES2761938T3 (da)
WO (5) WO2007136821A1 (da)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409846B2 (en) 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US9301519B2 (en) 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
IL273422B (en) * 2004-10-07 2022-07-01 Transmedics Inc Methods and systems for extracorporeal organ treatment
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US7754148B2 (en) 2006-12-27 2010-07-13 Progentech Limited Instrument for cassette for sample preparation
US7727473B2 (en) 2005-10-19 2010-06-01 Progentech Limited Cassette for sample preparation
CA2649703C (en) 2006-04-19 2019-01-08 Transmedics, Inc. Systems and methods for ex vivo organ care
WO2007136821A1 (en) 2006-05-22 2007-11-29 Biovest International Inc. Media circulation system for a cell cultureware module
WO2008109674A2 (en) * 2007-03-05 2008-09-12 Caridianbct, Inc. Cell expansion system and methods of use
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US9814230B2 (en) 2008-01-31 2017-11-14 Transmedics, Inc. Systems and methods for ex vivo lung care
GB0808373D0 (en) * 2008-05-09 2008-06-18 Synexa Life Sciences Pty Ltd Scalable cell culture bioreactor and cell culture process
AU2009282271B2 (en) 2008-08-12 2015-05-28 Terumo Bct, Inc. A predictor of when to harvest cells grown in a bioreactor
EP2346984A4 (en) * 2008-10-22 2013-10-30 Biovest Int Inc PERFUSION BIOREACTOR, CELL CULTURE SYSTEMS AND METHODS FOR PRODUCING CELLS AND CELL DERIVED PRODUCTS
US8211692B2 (en) * 2008-10-24 2012-07-03 Coskata, Inc. Bioconversion process using liquid phase having to enhance gas phase conversion
US9284523B2 (en) 2008-10-27 2016-03-15 Terumo Bct, Inc. Premounted fluid conveyance assembly for cell expansion system and method of use associated therewith
US8999046B2 (en) 2008-10-27 2015-04-07 Terumo Bct, Inc. Air removal chamber for a cell expansion system and method of use associated therewith
FR2941385B1 (fr) 2009-01-23 2011-04-01 Millipore Corp Procede pour fournir un circuit pour liquide biologique et circuit obtenu.
DE102009019868B4 (de) * 2009-05-06 2015-10-22 Hosokawa Alpine Ag Verfahrenstechnische Anlage für den Laborbetrieb
US9247729B2 (en) * 2009-05-29 2016-02-02 Institut Georges Lopez Systems and methods for preserving a human organ for transplantation
US9206383B2 (en) * 2009-12-07 2015-12-08 The Trustees Of Columbia University In The City Of New York Bioreactor, devices, systems and methods
US20120294742A1 (en) * 2009-12-08 2012-11-22 The Trustees Of Columbia University In The City Of New York Peristaltic pump devices, methods, and systems
EP2516682B1 (en) * 2009-12-22 2020-02-26 GE Healthcare Bio-Sciences AB A method for controlling culture parameters in a bioreactor
US9057045B2 (en) 2009-12-29 2015-06-16 Terumo Bct, Inc. Method of loading and distributing cells in a bioreactor of a cell expansion system
FR2955119B1 (fr) 2010-01-13 2012-12-28 Millipore Corp Circuit pour liquide biologique
AU2011220873B2 (en) 2010-02-23 2014-07-10 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
US20110265897A1 (en) * 2010-04-30 2011-11-03 Developmental Technologies, Llc Fertigation Efficacy Enhancement System And Associated Methods
JP6039547B2 (ja) 2010-05-05 2016-12-07 テルモ ビーシーティー、インコーポレーテッド 中空糸型バイオリアクターシステムにおいて成長させた接着細胞を再播種する方法
FR2960796B1 (fr) 2010-06-08 2014-01-24 Millipore Corp Dispositif pour une installation de traitement de liquide biologique
FR2960794B1 (fr) 2010-06-08 2012-07-27 Millipore Corp Dispositif pour une installation de traitement de liquide biologique
FR2960795B1 (fr) 2010-06-08 2012-07-27 Millipore Corp Dispositif pour une installation de traitement de liquide biologique
FR2961713B1 (fr) 2010-06-23 2012-08-10 Millipore Corp Poche pour circuit d'une installation de traitement de liquide biologique
FR2961711B1 (fr) 2010-06-23 2012-08-17 Millipore Corp Poche pour circuit d'une installation de traitement de liquide biologique
FR2963573B1 (fr) * 2010-08-03 2012-08-31 Millipore Corp Chariot de pompage pour une installation de traitement de liquide biologique
WO2012048298A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
FR2973396B1 (fr) 2011-03-28 2013-05-10 Millipore Corp Installation de traitement de liquide biologique
WO2012141055A1 (ja) * 2011-04-13 2012-10-18 株式会社日立製作所 細胞培養装置、及び搬送装置
CA3106469A1 (en) 2011-04-14 2012-10-18 Transmedics, Inc. Organ care solution for ex-vivo machine perfusion of donor lungs
WO2012151473A2 (en) 2011-05-04 2012-11-08 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
WO2012171030A2 (en) 2011-06-10 2012-12-13 Biovest International, Inc. Method and apparatus for antibody production and purification
WO2012171026A2 (en) * 2011-06-10 2012-12-13 Biovest International, Inc. Methods for high yield virus production
SG11201401135XA (en) * 2011-10-07 2014-10-30 Pall Technology Uk Ltd Fluid processing control system and related methods
US10087422B2 (en) * 2011-12-09 2018-10-02 President And Fellows Of Harvard College Organ chips and uses thereof
US9683207B2 (en) * 2012-05-01 2017-06-20 FiberCell Production Solutions LLC Method for growing cells in hollow fibers
ES2435092B1 (es) 2012-06-14 2014-09-09 Aglaris Cell S.L. Método y sistema de cultivo celular
FR2993572B1 (fr) 2012-07-23 2016-04-15 Emd Millipore Corp Circuit pour liquide biologique comportant une vanne a pincement
JP6466841B2 (ja) 2012-08-20 2019-02-06 テルモ ビーシーティー、インコーポレーテッド 細胞増殖システムのバイオリアクターにおける細胞の投入・分配方法
US9902928B2 (en) 2012-08-28 2018-02-27 Biovest International, Inc. Biomanufacturing suite and methods for large-scale production of cells, viruses, and biomolecules
US9725768B2 (en) 2012-08-31 2017-08-08 Biovest International, Inc. Methods for producing high-fidelity autologous idiotype vaccines
US10407657B2 (en) 2012-09-05 2019-09-10 Hitachi, Ltd. Valve mechanism, cell cultivation apparatus using same, and cell cultivation method
CN105793411B (zh) 2013-11-16 2018-04-17 泰尔茂比司特公司 生物反应器中的细胞扩增
USD727327S1 (en) * 2013-11-22 2015-04-21 Compliance Software, Inc. Compact stand with mobile scanner
KR102296181B1 (ko) * 2013-12-06 2021-08-31 인제대학교 산학협력단 복합 자극을 이용한 세포 배양 시스템
USD735883S1 (en) * 2013-12-30 2015-08-04 Illumina, Inc. Sample preparation instrument
EP3105311A1 (en) 2014-02-10 2016-12-21 Univercells NV System, apparatus and method for biomolecules production
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
US10077421B2 (en) 2014-04-24 2018-09-18 Terumo Bct, Inc. Measuring flow rate
JP6719387B2 (ja) 2014-04-28 2020-07-08 ビババイオセル エスピーエー 自動細胞培養及び回収装置
AU2015271799B2 (en) 2014-06-02 2019-07-11 Transmedics, Inc. Ex vivo organ care system
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
AU2015361996B2 (en) 2014-12-12 2019-09-26 Transmedics, Inc. Apparatus and method for organ perfusion
AU364136S (en) * 2015-02-05 2015-09-14 Gen Electric Compact bioreactor for cell cultivation
AU364138S (en) * 2015-02-05 2015-09-14 Gen Electric Stackable bioreactor for cell cultivation
US10611991B2 (en) * 2015-04-07 2020-04-07 University Of South Carolina Pulsatile perfusion bioreactor for mimicking, controlling, and optimizing blood vessel mechanics
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
DE102015112343A1 (de) * 2015-07-29 2017-02-02 Westfälische Wilhelms-Universität Münster Vorrichtung und Verfahren zum Aufbereiten von Körperflüssigkeiten
USD776825S1 (en) * 2015-08-25 2017-01-17 General Electric Company Bioreactor housing
CA2997267A1 (en) 2015-09-09 2017-03-16 Transmedics, Inc. Aortic cannula for ex vivo organ care system
US10323225B2 (en) 2015-10-20 2019-06-18 Locus Solutions Apparatus, systems and methods for growing microorganisms
CN108778651B (zh) * 2016-02-03 2021-06-18 米沃奇电动工具公司 用于配置往复锯的系统和方法
USD810084S1 (en) 2016-03-23 2018-02-13 Formfox, Inc. Mobile scanner
EP3464565A4 (en) 2016-05-25 2020-01-01 Terumo BCT, Inc. CELL EXPANSION
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
FR3053051B1 (fr) * 2016-06-24 2022-11-11 Cellprothera Cassette et automate de culture cellulaire
CN106467893B (zh) * 2016-08-22 2018-07-24 王铁苗 一种试验辅助装置
CN106244453B (zh) * 2016-08-22 2018-08-24 杭州荣泽生物科技有限公司 一种用于培养、测定及分析的细胞培育装置
CN106190843B (zh) * 2016-08-22 2018-06-15 刘力伟 一种多样本培养装置
CN106119110A (zh) * 2016-08-22 2016-11-16 诸葛洁婧 一种培养载体结构
CN106222089B (zh) * 2016-08-22 2018-09-21 王铁苗 一种试验辅助培养装置
CN106222090B (zh) * 2016-08-22 2018-07-24 王铁苗 一种试验辅助载体
CN106244457B (zh) * 2016-08-22 2018-08-03 日照安维信生物科技有限公司 一种试验用培养载体结构
CN106190839B (zh) * 2016-08-22 2018-08-24 杭州荣泽生物科技有限公司 一种可用于比对试验的细胞培养装置
CN106222087B (zh) * 2016-08-22 2018-07-24 王铁苗 一种样本培养载体
CN106282017B (zh) * 2016-08-22 2018-09-21 王铁苗 一种集成式样本培养装置
CN106047703B (zh) * 2016-08-22 2018-08-10 青岛爱博生物科技有限公司 一种试验样本培养装置
CN115044471A (zh) 2016-08-27 2022-09-13 三维生物科技有限公司 生物反应器
US20190382706A1 (en) * 2017-02-27 2019-12-19 Koji Tanabe Somatic cell production system
EP3656841A1 (en) 2017-03-31 2020-05-27 Terumo BCT, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US11518972B2 (en) * 2017-05-25 2022-12-06 Lun-Kuang Liu Movable cell incubator
JP2020532414A (ja) 2017-08-31 2020-11-12 マサチューセッツ インスティテュート オブ テクノロジー 中空糸膜濾過システムおよび生物学的に生成される生成物を製造するための方法
US10247724B1 (en) 2017-09-28 2019-04-02 Autobiologic Inc. Optically clear sealable petri dish bioreactor
GB201717652D0 (en) 2017-10-26 2017-12-13 Ge Healthcare Bio Sciences Ab Bioprocess System
CN107904170A (zh) * 2017-12-18 2018-04-13 上海白泽医疗器械有限公司 细胞培养模块及细胞培养系统
WO2019191685A1 (en) * 2018-03-30 2019-10-03 Arizona Board Of Regents On Behalf Of The University Of Arizona Workstation for automated control of an in vitro system
IL258738B (en) * 2018-04-16 2020-04-30 Pluristem Ltd Methods and compositions for formulating and dispensing pharmaceutical formulations
EP3790983B1 (en) * 2018-05-11 2023-07-05 Exothera SA Use of flexible or compressible liners in a system and method for clarifying a cell culture harvest solution
US20190352589A1 (en) * 2018-05-18 2019-11-21 Huacells Corporation Automated Cell Culturing
EP3584305B1 (en) * 2018-06-19 2021-07-28 Lun-Kuang Liu Movable cell incubator
WO2021111196A1 (en) * 2019-12-02 2021-06-10 Avant Meats Company Limited Methods of meat production by in vitro cell cultivation
CN115551989A (zh) * 2020-02-14 2022-12-30 艾克斯赛尔生物科学公司 用于细胞培养的气体和液体流动调节系统
USD937266S1 (en) * 2020-02-25 2021-11-30 Amazon Technologies, Inc. Pedestal scanner
CA3175039A1 (en) 2020-03-10 2021-09-16 Cellares Corporation Systems, devices, and methods for cell processing
USD962239S1 (en) 2020-08-20 2022-08-30 Amazon Technologies, Inc. Pedestal scanner
US20220135921A1 (en) * 2020-10-29 2022-05-05 Applied Materials, Inc. Methods and apparatus for cell development
CN112553072B (zh) * 2020-12-10 2022-04-08 上海艾众生物科技有限公司 用于生物反应器罐外循环的微流道动力设备
EP4301841A1 (en) * 2021-03-26 2024-01-10 TERUMO Kabushiki Kaisha Cell culturing system
WO2022202733A1 (en) * 2021-03-26 2022-09-29 Terumo Kabushiki Kaisha Cell culturing system
GB202105923D0 (en) 2021-04-26 2021-06-09 Cytiva Sweden Ab Reconfigurable bioprocessing systems
WO2023288314A1 (en) * 2021-07-15 2023-01-19 Georgia Tech Research Corporation Methods of determining viable cell count and impedance-based biosensors for the same

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3148624A (en) * 1961-06-21 1964-09-15 Alan W Baldwin Hydraulic pump
US4047844A (en) 1975-12-08 1977-09-13 Searle Cardio-Pulmonary Systems Inc. Blood pumping system
US4167046A (en) * 1977-12-12 1979-09-11 Andros, Inc. Blood pumping device
US4282902A (en) * 1979-05-04 1981-08-11 Becton Dickinson & Company Valve apparatus for simultaneous control of a plurality of fluid paths
US4417861A (en) 1981-08-10 1983-11-29 Monsanto Company Cell culture pumping system
DE3572381D1 (en) * 1984-05-25 1989-09-21 Isco Inc Peristaltic pump
US4804628A (en) 1984-10-09 1989-02-14 Endotronics, Inc. Hollow fiber cell culture device and method of operation
US4604038A (en) * 1985-03-08 1986-08-05 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Remotely operable peristaltic pump
EP0302894B1 (en) 1986-04-28 1992-11-19 Endotronics Inc. Method of culturing leukocytes
US4973558A (en) 1988-04-28 1990-11-27 Endotronics, Inc. Method of culturing cells using highly gas saturated media
US5416022A (en) 1988-08-10 1995-05-16 Cellex Biosciences, Inc. Cell culture apparatus
WO1991002049A1 (en) 1989-08-04 1991-02-21 Peter Grandics An integrated cell culture-protein purification system for the automated production and purification of cell culture products
AR244863A1 (es) * 1989-09-07 1993-11-30 Marcelo Alberto Hoegner Una valvula multiple y un equipo de esterilizacion que la incorpora.
US5656421A (en) 1990-02-15 1997-08-12 Unisyn Technologies, Inc. Multi-bioreactor hollow fiber cell propagation system and method
US5098261A (en) * 1990-05-04 1992-03-24 Brandel Corporation Peristaltic pump and method for adjustable flow regulation
US5330915A (en) 1991-10-18 1994-07-19 Endotronics, Inc. Pressure control system for a bioreactor
US5882918A (en) * 1995-08-08 1999-03-16 Genespan Corporation Cell culture incubator
US5622857A (en) * 1995-08-08 1997-04-22 Genespan Corporation High performance cell culture bioreactor and method
WO1996005285A1 (en) * 1994-08-16 1996-02-22 Powell Biological Machines Ltd. Cell culture apparatus
US5554123A (en) * 1994-10-31 1996-09-10 Glenn Herskowitz Portable infusion pump
US5688687A (en) * 1995-06-07 1997-11-18 Aastrom Biosciences, Inc. Bioreactor for mammalian cell growth and maintenance
US5998184A (en) 1997-10-08 1999-12-07 Unisyn Technologies, Inc. Basket-type bioreactor
US6001585A (en) 1997-11-14 1999-12-14 Cellex Biosciences, Inc. Micro hollow fiber bioreactor
US6780617B2 (en) * 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
JP3461725B2 (ja) * 1998-06-26 2003-10-27 東京エレクトロン株式会社 処理液供給装置及び処理液供給方法
NO20002828D0 (no) 2000-06-02 2000-06-02 Statens Inst For Folkehelse Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav
WO2002087662A1 (en) * 2001-04-27 2002-11-07 Nexell Therapeutics Inc. Cell processing and fluid transfer apparatus and method of use
US6673595B2 (en) * 2001-08-27 2004-01-06 Biocrystal, Ltd Automated cell management system for growth and manipulation of cultured cells
DK2330181T3 (da) 2002-04-08 2019-03-25 Octane Biotech Inc Automatiseret vævsmanipulationssystem
US6733252B2 (en) * 2002-05-10 2004-05-11 Fqubed Fluid-handling systems and components comprising a bladder pump, a methods therefor
US20030217957A1 (en) * 2002-05-24 2003-11-27 Bowman Joseph H. Heat seal interface for a disposable medical fluid unit
DE10244090A1 (de) * 2002-09-23 2004-04-01 Ismatec S.A. Schlauchkassette für eine peristaltische Pumpe
US7377686B2 (en) * 2003-09-04 2008-05-27 Millipore Corporation Disposable mixing system
EP1668249B1 (de) * 2003-09-26 2008-03-19 Ismatec SA, Laboratoriumstechnik Peristaltische pumpe
WO2005087915A2 (en) 2004-03-08 2005-09-22 Biovest International, Inc. Use of ethanolamine for enhancing cell growth in membrane systems
WO2005090403A2 (en) 2004-03-12 2005-09-29 Biovest International, Inc. Method and apparatus for antibody purification
US9499780B2 (en) * 2004-05-26 2016-11-22 Octane Biotech Inc. Advanced tissue engineering system
US7143777B2 (en) * 2004-07-20 2006-12-05 Ing Tzon Co., Ltd. Control valve having pressure balance effect
CN101321856A (zh) 2005-05-09 2008-12-10 萨克松尼亚生物科技有限责任公司 用于细胞培养模块的供应系统
US7875184B2 (en) * 2005-09-22 2011-01-25 Eastman Chemical Company Crystallized pellet/liquid separator
WO2007106232A2 (en) * 2006-02-27 2007-09-20 Fluidnet Corporation Volume measurement using gas laws
WO2007098607A1 (en) 2006-03-03 2007-09-07 Amorfix Life Sciences Ltd. Methods and compositions to treat and detect misfolded-sod1 mediated diseases
CA2649703C (en) 2006-04-19 2019-01-08 Transmedics, Inc. Systems and methods for ex vivo organ care
EP1961806B1 (en) 2006-05-13 2019-03-27 Pall Life Sciences Belgium Disposable bioreactor
WO2007136821A1 (en) 2006-05-22 2007-11-29 Biovest International Inc. Media circulation system for a cell cultureware module
JP4585563B2 (ja) * 2007-12-03 2010-11-24 株式会社コガネイ 薬液供給装置およびポンプ組立体
CA2739918A1 (en) 2008-10-07 2010-04-15 Biovest International, Inc. Methods for inducing a sustained immune response against a b-cell idiotype using autologous anti-idiotypic vaccines
EP2346984A4 (en) 2008-10-22 2013-10-30 Biovest Int Inc PERFUSION BIOREACTOR, CELL CULTURE SYSTEMS AND METHODS FOR PRODUCING CELLS AND CELL DERIVED PRODUCTS
US9284523B2 (en) 2008-10-27 2016-03-15 Terumo Bct, Inc. Premounted fluid conveyance assembly for cell expansion system and method of use associated therewith
US20140037615A1 (en) 2010-08-13 2014-02-06 Biovest International, Inc. Materials and methods for designing autologous idiotype vaccines and treatment of b-cell malignancies
WO2012048298A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
EP2637691A4 (en) 2010-11-08 2015-09-02 Biovest Int Inc MATERIALS AND METHOD FOR CONTROLLING AN IMMUNE RESPONSE TO AN EPITOP
WO2012171030A2 (en) 2011-06-10 2012-12-13 Biovest International, Inc. Method and apparatus for antibody production and purification
WO2012171026A2 (en) 2011-06-10 2012-12-13 Biovest International, Inc. Methods for high yield virus production
WO2013086418A1 (en) 2011-12-09 2013-06-13 Biovest International, Inc. Tumor-specifc gm-csf cytokine response as predictor of cancer vaccine effectiveness
US9902928B2 (en) 2012-08-28 2018-02-27 Biovest International, Inc. Biomanufacturing suite and methods for large-scale production of cells, viruses, and biomolecules

Also Published As

Publication number Publication date
US9441195B2 (en) 2016-09-13
EP2404991A2 (en) 2012-01-11
US20140024012A1 (en) 2014-01-23
US8383397B2 (en) 2013-02-26
ES2761938T3 (es) 2020-05-21
US20090269841A1 (en) 2009-10-29
EP2027247A2 (en) 2009-02-25
WO2007139748A2 (en) 2007-12-06
WO2007139742A1 (en) 2007-12-06
EP2404991A3 (en) 2013-05-22
EP2029722A1 (en) 2009-03-04
DE602007012238D1 (de) 2011-03-10
US10723993B2 (en) 2020-07-28
US20090215022A1 (en) 2009-08-27
US8540499B2 (en) 2013-09-24
WO2007139747A1 (en) 2007-12-06
WO2007136821A1 (en) 2007-11-29
US11345882B2 (en) 2022-05-31
EP2027247B1 (en) 2011-01-26
WO2007139748A3 (en) 2008-03-13
US9534198B2 (en) 2017-01-03
EP2029722B1 (en) 2019-10-16
ATE496987T1 (de) 2011-02-15
US20160362650A1 (en) 2016-12-15
WO2007139746A1 (en) 2007-12-06
US20130058907A1 (en) 2013-03-07
US20160362652A1 (en) 2016-12-15

Similar Documents

Publication Publication Date Title
DK2029722T3 (da) Fremgangsmåde og system til celleproduktion
EA201892695A1 (ru) Одноразовый биореактор
WO2003087292A3 (en) Automated tissue engineering system
DE602005002213D1 (de) Automatische Vorrichtung zur Kultur von Zellen unter Verwendung von Autoklavsterilisation und Verfahren zu seiner Verwendung
EP2566951B1 (en) Method of reseeding adherent cells grown in a hollow fiber bioreactor system
RU2373273C2 (ru) Устройство для непрерывной культуры с мобильным сосудом, позволяющим выполнять отбор наиболее подходящих вариантов клеток
MX2009013735A (es) Crecimiento de algas para biocombustibles.
DK2173853T3 (da) Indretning, system og fremgangsmåde til at overvåge og/eller dyrke mikroskopiske objekter
EA201300461A1 (ru) Локализованное аэрационное оборудование для выращивания шампиньонов и других культивируемых грибов и способ его использования
WO2011063218A3 (en) Cell collecting devices and methods for collecting cells
DE60213432D1 (de) Verfahren und anlage zur züchtung von organischen gewebekulturen
CN104893974A (zh) 可在线动态实时监测的便捷式干细胞扩增培养设备
WO2009141163A3 (de) Bioreaktor und verfahren zum kultivieren von zellen und geweben
ATE376583T1 (de) Verfahren zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
KR20130011778A (ko) 이산화탄소를 이용한 교육용 미생물 배양 키트
CN207330946U (zh) 一种生物实验用培养箱
KR102041799B1 (ko) 버섯 배지의 유해가스 배출장치 및 이를 이용한 유해가스 배출방법
WO2008100033A1 (en) Pressure controllable incubation system
CN102010821A (zh) 细胞气态暴露实验控制装置
WO2004033616A8 (de) Einrichtung zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
CN104726339B (zh) 一种微藻的固定化养殖方法
CN215935771U (zh) 一种野生灵芝用多功能培育箱
CN102010823A (zh) 细胞培养液流动供应装置
CN105368712B (zh) 一种组织工程皮肤产业化培养装置
CN102061258A (zh) 细胞暴露缺氧环境实验装置