DK1508047T3 - Method for Identifying Immunoreactive Peptides - Google Patents

Method for Identifying Immunoreactive Peptides

Info

Publication number
DK1508047T3
DK1508047T3 DK03735383T DK03735383T DK1508047T3 DK 1508047 T3 DK1508047 T3 DK 1508047T3 DK 03735383 T DK03735383 T DK 03735383T DK 03735383 T DK03735383 T DK 03735383T DK 1508047 T3 DK1508047 T3 DK 1508047T3
Authority
DK
Denmark
Prior art keywords
peptides
immunoreactive peptides
identifying
tumorous
identifying immunoreactive
Prior art date
Application number
DK03735383T
Other languages
Danish (da)
Inventor
Toni Weinschenk
Hans Georg Rammensee
Original Assignee
Immatics Biotechnologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Application granted granted Critical
Publication of DK1508047T3 publication Critical patent/DK1508047T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention relates to a method for identifying immunoreactive peptides. According to said method, a sample consisting of tumorous and corresponding healthy tissue is first prepared, the tumour-specific expression profile is subsequently determined and antigenic peptides are isolated from the tumorous tissue and analysed. The respective data that has been obtained is then matched and peptides are identified on the basis of said matched data.
DK03735383T 2002-05-29 2003-05-14 Method for Identifying Immunoreactive Peptides DK1508047T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10225139A DE10225139A1 (en) 2002-05-29 2002-05-29 Methods for the identification of immunoreactive peptides
PCT/EP2003/005038 WO2003100432A2 (en) 2002-05-29 2003-05-14 Method for identifying immunoreactive peptides

Publications (1)

Publication Number Publication Date
DK1508047T3 true DK1508047T3 (en) 2008-10-20

Family

ID=29557590

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03735383T DK1508047T3 (en) 2002-05-29 2003-05-14 Method for Identifying Immunoreactive Peptides

Country Status (13)

Country Link
EP (1) EP1508047B1 (en)
JP (1) JP2005535299A (en)
AT (1) ATE403874T1 (en)
AU (1) AU2003236645B2 (en)
CA (1) CA2486738C (en)
CY (1) CY1108358T1 (en)
DE (2) DE10225139A1 (en)
DK (1) DK1508047T3 (en)
ES (1) ES2311710T3 (en)
IL (2) IL165398A0 (en)
PT (1) PT1508047E (en)
SI (1) SI1508047T1 (en)
WO (1) WO2003100432A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1782070T3 (en) * 2004-06-17 2011-01-03 Mannkind Corp Tumor-associated antigen profiles in cancer diagnosis and immunotherapy
EP1994181A4 (en) * 2006-02-27 2010-05-19 Univ Arizona Identification and use of novopeptides for the treatment of cancer
US9732131B2 (en) 2006-02-27 2017-08-15 Calviri, Inc. Identification and use of novopeptides for the treatment of cancer
US20090004213A1 (en) * 2007-03-26 2009-01-01 Immatics Biotechnologies Gmbh Combination therapy using active immunotherapy
GB201004575D0 (en) * 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers
GB201004551D0 (en) * 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer
GB201019331D0 (en) * 2010-03-19 2010-12-29 Immatics Biotechnologies Gmbh Methods for the diagnosis and treatment of cancer based on AVL9
GB201006360D0 (en) 2010-04-16 2010-06-02 Immatics Biotechnologies Gmbh Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development
GB201423361D0 (en) 2014-12-30 2015-02-11 Immatics Biotechnologies Gmbh Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
DE102016123893A1 (en) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T cell receptors with improved binding
KR102639592B1 (en) 2016-12-08 2024-02-21 이매틱스 바이오테크놀로지스 게엠베하 T cell receptors with improved pairing
US11484581B2 (en) 2017-06-02 2022-11-01 Arizona Board Of Regents On Behalf Of Arizona State University Method to create personalized canine cancer vaccines
WO2019055618A1 (en) 2017-09-15 2019-03-21 Arizona Board Of Regents On Behalf Of Arizona State University Methods of classifying response to immunotherapy for cancer
DE102018122546B3 (en) 2018-09-14 2019-12-05 Immatics Biotechnologies Gmbh High-throughput peptide MHC affinity screening method for TCR ligands
DE102019114735A1 (en) * 2019-06-02 2020-12-03 PMCR GmbH Class I and II HLA tumor antigen peptides for the treatment of breast cancer
US20210032370A1 (en) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Recruiting agent further binding an mhc molecule
DE102019121007A1 (en) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Antigen binding proteins that specifically bind to MAGE-A
WO2021067550A1 (en) 2019-10-02 2021-04-08 Arizona Board Of Regents On Behalf Of Arizona State University Methods and compositions for identifying neoantigens for use in treating and preventing cancer
TW202309071A (en) 2021-05-05 2023-03-01 德商英麥提克生物技術股份有限公司 Antigen binding proteins specifically binding prame
WO2023006828A1 (en) 2021-07-27 2023-02-02 Immatics Biotechnologies Gmbh Antigen binding proteins specifically binding ct45

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156317A (en) * 1996-11-12 2000-12-05 City Of Hope Immuno-reactive peptide CTL epitopes of human cytomegalovirus
DE10225144A1 (en) * 2002-05-29 2003-12-18 Immatics Biotechnologies Gmbh Tumor-associated peptides binding to MHC molecules

Also Published As

Publication number Publication date
AU2003236645A1 (en) 2003-12-12
EP1508047B1 (en) 2008-08-06
JP2005535299A (en) 2005-11-24
PT1508047E (en) 2008-10-02
WO2003100432A2 (en) 2003-12-04
ATE403874T1 (en) 2008-08-15
CY1108358T1 (en) 2014-02-12
SI1508047T1 (en) 2008-12-31
EP1508047A2 (en) 2005-02-23
IL165398A (en) 2013-04-30
ES2311710T3 (en) 2009-02-16
CA2486738A1 (en) 2003-12-04
DE10225139A1 (en) 2004-02-26
IL165398A0 (en) 2006-01-15
DE50310283D1 (en) 2008-09-18
WO2003100432A3 (en) 2004-06-03
CA2486738C (en) 2011-07-12
AU2003236645B2 (en) 2009-06-18

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