US5912015A
(en)
|
1992-03-12 |
1999-06-15 |
Alkermes Controlled Therapeutics, Inc. |
Modulated release from biocompatible polymers
|
US6514533B1
(en)
|
1992-06-11 |
2003-02-04 |
Alkermas Controlled Therapeutics, Inc. |
Device for the sustained release of aggregation-stabilized, biologically active agent
|
US5674534A
(en)
*
|
1992-06-11 |
1997-10-07 |
Alkermes, Inc. |
Composition for sustained release of non-aggregated erythropoietin
|
US5716644A
(en)
*
|
1992-06-11 |
1998-02-10 |
Alkermes, Inc. |
Composition for sustained release of non-aggregated erythropoietin
|
JPH08503950A
(ja)
*
|
1992-12-02 |
1996-04-30 |
アルカーメス・コントロールド・セラピユーテイクス・インコーポレーテツド |
徐放性成長ホルモン含有マイクロスフェア
|
DE69614685T2
(de)
*
|
1995-06-07 |
2002-06-27 |
Alkermes Inc |
Mittel zur verzögerten freisetzung von menschlichem wachstumshormon
|
EP1080718A1
(en)
*
|
1995-06-07 |
2001-03-07 |
Alkermes Controlled Therapeutics, Inc. |
Composition for sustained release of human growth hormone
|
JP2000507912A
(ja)
*
|
1995-08-31 |
2000-06-27 |
アルカームズ コントロールド セラピューティックス,インコーポレイテッド |
作用剤の徐放性組成物
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
TW448055B
(en)
*
|
1995-09-04 |
2001-08-01 |
Takeda Chemical Industries Ltd |
Method of production of sustained-release preparation
|
CA2192773C
(en)
*
|
1995-12-15 |
2008-09-23 |
Hiroaki Okada |
Production of sustained-release preparation for injection
|
US6419961B1
(en)
|
1996-08-29 |
2002-07-16 |
Takeda Chemical Industries, Ltd. |
Sustained release microcapsules of a bioactive substance and a biodegradable polymer
|
CA2219698C
(en)
*
|
1996-10-31 |
2007-09-04 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation
|
DE69719367T2
(de)
*
|
1996-12-20 |
2003-10-16 |
Takeda Chemical Industries Ltd |
Verfahren zur herstellung einer zusammensetzung mit verzoegerter abgabe
|
US6287587B2
(en)
*
|
1997-07-15 |
2001-09-11 |
Takeda Chemical Industries, Ltd. |
Process for producing sustained-release preparation by in-water drying
|
US6191107B1
(en)
|
1997-09-26 |
2001-02-20 |
Takeda Chemical Industries, Ltd. |
Complex of human growth hormone and zinc
|
US20060165606A1
(en)
|
1997-09-29 |
2006-07-27 |
Nektar Therapeutics |
Pulmonary delivery particles comprising water insoluble or crystalline active agents
|
SE512663C2
(sv)
|
1997-10-23 |
2000-04-17 |
Biogram Ab |
Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
|
NZ525914A
(en)
|
1998-03-10 |
2004-03-26 |
Genentech Inc |
Novel polypeptides and nucleic acids encoding the same
|
AU740405B2
(en)
|
1998-05-15 |
2001-11-01 |
Genentech Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
EP3112468A1
(en)
|
1998-05-15 |
2017-01-04 |
Genentech, Inc. |
Il-17 homologous polypeptides and therapeutic uses thereof
|
US20020172678A1
(en)
|
2000-06-23 |
2002-11-21 |
Napoleone Ferrara |
EG-VEGF nucleic acids and polypeptides and methods of use
|
EP1978029A3
(en)
|
1999-06-15 |
2008-10-15 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids endoding the same
|
KR20020063853A
(ko)
|
1999-09-17 |
2002-08-05 |
다케다 야쿠힌 고교 가부시키가이샤 |
단백질 분체의 제조 방법
|
CA2391455A1
(en)
|
1999-12-01 |
2001-06-07 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
EP2290081A3
(en)
|
1999-12-23 |
2012-08-01 |
Genentech, Inc. |
IL-17 homologous polypeptide and therapeutic uses thereof
|
EP1246917B1
(en)
|
2000-01-13 |
2009-03-04 |
Genentech, Inc. |
Human stra6 polypeptides
|
CA2400845A1
(en)
*
|
2000-02-21 |
2001-08-23 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation of physiologically active compound slightly soluble in water and production process and use of the same
|
US6740520B2
(en)
|
2000-03-21 |
2004-05-25 |
Genentech, Inc. |
Cytokine receptor and nucleic acids encoding the same
|
DE60120372T2
(de)
|
2000-03-24 |
2007-07-05 |
Genentech Inc., San Francisco |
Verwendung von insulin zur behandlung von knorpelkrankheiten
|
US6998137B2
(en)
*
|
2000-04-07 |
2006-02-14 |
Macromed, Inc. |
Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix
|
US7871598B1
(en)
|
2000-05-10 |
2011-01-18 |
Novartis Ag |
Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
|
DE10024451A1
(de)
*
|
2000-05-18 |
2001-11-29 |
Asta Medica Ag |
Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
|
AU6531101A
(en)
|
2000-06-02 |
2001-12-17 |
Genentech Inc |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
EP2014298A3
(en)
|
2000-08-24 |
2009-10-07 |
Genentech, Inc. |
Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
|
EP1944317A3
(en)
|
2000-09-01 |
2008-09-17 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US6673580B2
(en)
|
2000-10-27 |
2004-01-06 |
Genentech, Inc. |
Identification and modification of immunodominant epitopes in polypeptides
|
DE60136958D1
(de)
|
2000-12-01 |
2009-01-22 |
Takeda Pharmaceutical |
Verfahren zur herstellung einer zubereitung mit einer bioaktiven substanz
|
EP1356809A4
(en)
*
|
2000-12-28 |
2008-05-14 |
Takeda Pharmaceutical |
SUSTAINED RELEASE PREPARATIONS
|
DE10114178A1
(de)
|
2001-03-23 |
2002-10-10 |
Aventis Pharma Gmbh |
Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
JP2003081865A
(ja)
*
|
2001-09-12 |
2003-03-19 |
Ltt Institute Co Ltd |
水不溶性徐放性組成物、その製剤及びその製造方法
|
MXPA04005865A
(es)
|
2001-12-19 |
2004-09-13 |
Nektar Therapeutics |
Suministro de aminoglucosidos a los pulmones.
|
JP2005518212A
(ja)
|
2002-02-25 |
2005-06-23 |
ジェネンテック・インコーポレーテッド |
新規な1型サイトカインレセプターglm−r
|
DE10227232A1
(de)
|
2002-06-18 |
2004-01-15 |
Aventis Pharma Deutschland Gmbh |
Saure Insulinzubereitungen mit verbesserter Stabilität
|
CA2512052C
(en)
|
2002-12-31 |
2016-06-21 |
Altus Pharmaceuticals Inc. |
Human growth hormone crystals and methods for preparing them
|
WO2004073749A1
(ja)
*
|
2003-02-19 |
2004-09-02 |
Takeda Pharmaceutical Company Limited |
徐放性製剤用の分散剤
|
CN100361651C
(zh)
*
|
2003-03-26 |
2008-01-16 |
日本株式会社Ltt生物医药 |
用于靶向药物送递和持续药物释放的静脉内纳米颗粒
|
CN102258464A
(zh)
|
2003-04-04 |
2011-11-30 |
健泰科生物技术公司 |
高浓度抗体和蛋白制剂
|
WO2004096179A1
(en)
*
|
2003-05-01 |
2004-11-11 |
Ltt Bio-Pharma Co., Ltd. |
Zinc-containing sustained-release composition, its preparation, and method for producing the same
|
JP2004331750A
(ja)
|
2003-05-02 |
2004-11-25 |
Canon Inc |
ポリヒドロキシアルカノエートを含有する磁性構造体及びその製造方法ならびにその用途
|
SI1636593T1
(sl)
|
2003-06-06 |
2009-08-31 |
Genentech Inc |
Moduliranje interakcije med beta-verigo HGF in c-met
|
MX341074B
(es)
|
2003-07-08 |
2016-08-05 |
Genentech Inc |
Polipeptidos heterologos il-17 a/f y usos terapeuticos de los mismos.
|
WO2005025543A2
(en)
*
|
2003-09-08 |
2005-03-24 |
Alkermes Controlled Therapeutics, Inc. |
Polymer-based sustained release device and method for preparation
|
EP2336178A1
(en)
|
2003-12-11 |
2011-06-22 |
Genentech, Inc. |
Methods and compositions for inhibiting C-Met dimerization and activation
|
US7481997B1
(en)
|
2004-02-12 |
2009-01-27 |
Montana State University |
Snow mountain virus genome sequence, virus-like particles and methods of use
|
ATE430763T1
(de)
|
2004-03-30 |
2009-05-15 |
Nsgene As |
Therapeutische verwendung des wachstumsfaktors nsg33
|
US7919577B2
(en)
|
2004-10-27 |
2011-04-05 |
Colorado Seminary |
Adrenocorticotropic hormone analogs and related methods
|
WO2008018854A2
(en)
|
2005-06-06 |
2008-02-14 |
The Rockefeller University |
Bactiophage lysins for bacillus anthracis
|
JP2008541781A
(ja)
|
2005-06-06 |
2008-11-27 |
ジェネンテック・インコーポレーテッド |
異なる遺伝子に対するトランスジェニック動物、および遺伝子の特徴づけのためのその使用
|
PL2322552T3
(pl)
|
2005-06-21 |
2016-08-31 |
Xoma Us Llc |
PRZECIWCIAŁA WIĄŻĄCE IL-1β I ICH FRAGMENTY
|
US7582291B2
(en)
|
2005-06-30 |
2009-09-01 |
The Rockefeller University |
Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
|
US7931902B2
(en)
|
2005-08-15 |
2011-04-26 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
ATE491026T1
(de)
|
2005-08-24 |
2010-12-15 |
Univ Rockefeller |
Ply-gbs-lysinmutanten
|
US20090293137A1
(en)
|
2005-11-21 |
2009-11-26 |
Genentech, Inc. |
Novel Gene Disruptions, Compositions and Methods Relating Thereto
|
NZ568809A
(en)
|
2005-12-22 |
2011-08-26 |
Genentech Inc |
Recovering and purification of VEGF proteins from prokaryotic cells using polyanionic agents
|
EP1985309B1
(en)
|
2005-12-26 |
2016-11-23 |
LTT Bio-Pharma Co., Ltd. |
Nanoparticles containing water-soluble non-peptide low-molecular weight drug
|
US20080311107A1
(en)
|
2006-02-17 |
2008-12-18 |
Genetech, Inc. |
Novel Gene Disruptions, Compositions and Methods Relating Thereto
|
EP2389951A1
(en)
|
2006-03-23 |
2011-11-30 |
Novartis AG |
Anti-tumor cell antigen antibody therapeutics
|
EP2002259B1
(en)
|
2006-04-10 |
2012-05-16 |
Genentech, Inc. |
Disheveled PDZ modulators
|
CA2649387A1
(en)
|
2006-04-19 |
2008-03-27 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
EP3124045A3
(en)
|
2006-12-20 |
2017-05-03 |
Xoma (Us) Llc |
Treatment of il-1 beta related diseases
|
CN101361968B
(zh)
|
2007-08-06 |
2011-08-03 |
健能隆医药技术(上海)有限公司 |
白介素-22在治疗脂肪肝中的应用
|
JP5536666B2
(ja)
|
2007-12-20 |
2014-07-02 |
ゾーマ (ユーエス) リミテッド ライアビリティ カンパニー |
痛風の治療のための方法
|
RS56632B1
(sr)
|
2008-10-17 |
2018-03-30 |
Sanofi Aventis Deutschland |
Kombinacija insulina i glp-1-agonista
|
MX2012004303A
(es)
|
2009-10-15 |
2012-06-25 |
Genentech Inc |
Factores de crecimiento de fibroblasto quimericos con especificacion de receptor alterada.
|
US8771693B2
(en)
|
2009-10-27 |
2014-07-08 |
Beth Israel Deaconess Medical Center, Inc. |
Methods and compositions for the generation and use of conformation-specific antibodies
|
PT3345593T
(pt)
|
2009-11-13 |
2023-11-27 |
Sanofi Aventis Deutschland |
Composição farmacêutica compreendendo despro36exendina- 4(1-39)-lys6-nh2 e metionina
|
ES2855146T3
(es)
|
2009-11-13 |
2021-09-23 |
Sanofi Aventis Deutschland |
Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina
|
KR20120113265A
(ko)
|
2010-01-15 |
2012-10-12 |
유니버시티 오브 메디신 앤드 덴티스트리 오브 뉴 저지 |
골 치료를 촉진시키기 위한 바나듐 화합물의 용도
|
TR201905081T4
(tr)
|
2010-03-22 |
2019-05-21 |
Hoffmann La Roche |
Protein içeren formülasyonların stabilizasyonu için yararlı bileşimler ve yöntemler.
|
BR112012027828A2
(pt)
|
2010-05-03 |
2016-08-09 |
Genentech Inc |
composição de matéria, artigo de fabricação e método de redução da viscosidade de uma formulação contendo proteína e de preparação de uma formulação aquosa contendo proteína
|
WO2011163458A2
(en)
|
2010-06-24 |
2011-12-29 |
Genentech, Inc. |
Compositions and methods for stabilizing protein-containing formulations
|
HUE031181T2
(en)
|
2010-08-30 |
2017-06-28 |
Sanofi Aventis Deutschland |
Use of AVE0010 for the manufacture of a medicament for the treatment of type 2 diabetes
|
CN102380091A
(zh)
|
2010-08-31 |
2012-03-21 |
健能隆医药技术(上海)有限公司 |
白介素-22在治疗病毒性肝炎中的应用
|
EP2621512B1
(en)
|
2010-10-01 |
2016-04-06 |
NsGene A/S |
Use of meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain
|
JP6080763B2
(ja)
|
2010-10-08 |
2017-02-15 |
シャンハイ クーシン バイオテック カンパニー,リミテッド |
モエシンモジュレーターおよびその使用
|
WO2012045281A1
(en)
|
2010-10-08 |
2012-04-12 |
Shanghai Kexin Biotech Co., Ltd. |
Diagnostic and therapeutic uses of moesin fragments
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
US10487114B2
(en)
|
2011-04-27 |
2019-11-26 |
Beth Israel Deaconess Medical Center, Inc. |
Methods for administering peptides for the generation of effective c/s conformation-specific antibodies to a human subject in need thereof
|
US9821032B2
(en)
|
2011-05-13 |
2017-11-21 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
|
CN103917241A
(zh)
|
2011-08-29 |
2014-07-09 |
赛诺菲-安万特德国有限公司 |
用于2型糖尿病患者中的血糖控制的药物组合
|
AR087744A1
(es)
|
2011-09-01 |
2014-04-16 |
Sanofi Aventis Deutschland |
Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
|
EP3091029B1
(en)
|
2011-10-31 |
2022-12-28 |
F. Hoffmann-La Roche AG |
Anti-il13 antibody formulations
|
WO2013096516A1
(en)
|
2011-12-19 |
2013-06-27 |
Xoma Technology Ltd. |
Methods for treating acne
|
CA2863224A1
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Ultralong complementarity determining regions and uses thereof
|
AU2013208007A1
(en)
|
2012-01-09 |
2014-07-31 |
The Scripps Research Institute |
Humanized antibodies with ultralong CDR3
|
US9688747B2
(en)
|
2013-03-15 |
2017-06-27 |
Beth Israel Deaconess Medical Center, Inc. |
Methods and compositions for the generation and use of conformation-specific antibodies
|
AU2014290361B2
(en)
|
2013-07-18 |
2019-04-18 |
Taurus Biosciences, Llc |
Humanized antibodies with ultralong complementarity determining regions
|
US20160168231A1
(en)
|
2013-07-18 |
2016-06-16 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
US10286078B2
(en)
|
2013-09-13 |
2019-05-14 |
The California Institute For Biomedical Research |
Modified therapeutic agents and compositions thereof
|
EP3057991B8
(en)
|
2013-10-15 |
2019-09-04 |
The Scripps Research Institute |
Chimeric antigen receptor t cell switches and uses thereof
|
ES2845924T3
(es)
|
2013-10-15 |
2021-07-28 |
Scripps Research Inst |
Interruptores de células T con receptores de antígenos quiméricos peptídicos y usos de los mismos
|
CN104623639A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
白介素22二聚体在制备治疗胰腺炎药物中的应用
|
CN104623637A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
Il-22二聚体在制备静脉注射药物中的应用
|
CA2933701C
(en)
|
2013-12-18 |
2022-05-31 |
The California Institute For Biomedical Research |
Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof
|
JP6970615B2
(ja)
|
2014-12-12 |
2021-11-24 |
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
インスリングラルギン/リキシセナチド固定比処方
|
NL2014230B1
(en)
|
2015-02-04 |
2016-10-12 |
Stichting Vu-Vumc |
Wound healing formulation.
|
MA41629A
(fr)
|
2015-03-04 |
2018-01-09 |
Center For Human Reproduction |
Compositions et méthodes d'utilisation de l'hormone anti-müllérienne pour le traitement de l'infertilité
|
TWI748945B
(zh)
|
2015-03-13 |
2021-12-11 |
德商賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患治療
|
TW201705975A
(zh)
|
2015-03-18 |
2017-02-16 |
賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患之治療
|
US10800828B2
(en)
|
2015-03-26 |
2020-10-13 |
The Scripps Research Institute |
Switchable non-scFv chimeric receptors, switches, and methods of use thereof to treat cancer
|
US11091546B2
(en)
|
2015-04-15 |
2021-08-17 |
The Scripps Research Institute |
Optimized PNE-based chimeric receptor T cell switches and uses thereof
|
EP3310376A4
(en)
|
2015-06-17 |
2019-01-23 |
The California Institute for Biomedical Research |
MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF
|
JP5938762B1
(ja)
|
2015-09-01 |
2016-06-22 |
日揮株式会社 |
マイクロカプセル製剤及びその製造方法
|
EP3442562B1
(en)
|
2016-04-15 |
2022-09-21 |
Evive Biotechnology (Shanghai) Ltd |
An il-22 dimer for use in treating necrotizing enterocolitis
|
AU2017345479B2
(en)
|
2016-10-19 |
2024-03-21 |
The Scripps Research Institute |
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
|
WO2020205716A1
(en)
|
2019-04-01 |
2020-10-08 |
Genentech, Inc. |
Compositions and methods for stabilizing protein-containing formulations
|
JP2022544549A
(ja)
|
2019-08-12 |
2022-10-19 |
ピュリノミア バイオテック, インコーポレイテッド |
Cd39発現細胞のadcc標的化を介してt細胞媒介性免疫応答を促進及び増強するための方法及び組成物
|
CA3158893A1
(en)
|
2019-10-24 |
2021-04-29 |
Minotaur Therapeutics, Inc. |
Chimeric cytokine modified antibodies and methods of use thereof
|
JP2024517759A
(ja)
|
2021-04-28 |
2024-04-23 |
ミノトール セラピューティクス インコーポレイテッド |
ヒト化キメラウシ抗体および使用方法
|
WO2022233989A1
(en)
|
2021-05-06 |
2022-11-10 |
Hoba Therapeutics Aps |
Prevention and treatment of chemotherapy-induced neuropathic pain
|
WO2023104960A1
(en)
|
2021-12-10 |
2023-06-15 |
Hoba Therapeutics Aps |
Treatment of nociceptive pain
|