DE60313866D1 - Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür - Google Patents

Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür

Info

Publication number
DE60313866D1
DE60313866D1 DE60313866T DE60313866T DE60313866D1 DE 60313866 D1 DE60313866 D1 DE 60313866D1 DE 60313866 T DE60313866 T DE 60313866T DE 60313866 T DE60313866 T DE 60313866T DE 60313866 D1 DE60313866 D1 DE 60313866D1
Authority
DE
Germany
Prior art keywords
alpha
amino acid
acid amide
nucleic acids
racemase activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60313866T
Other languages
English (en)
Other versions
DE60313866T2 (de
Inventor
Wilhelmus Hubertus Boesten
Petronella C Raemakers-Franken
Theodorus Sonke
Gerrit Jan Euverink
Pieter Grijpstra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Application granted granted Critical
Publication of DE60313866D1 publication Critical patent/DE60313866D1/de
Publication of DE60313866T2 publication Critical patent/DE60313866T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DE60313866T 2002-06-14 2003-06-13 Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür Expired - Lifetime DE60313866T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP02100711 2002-06-14
EP02100711 2002-06-14
EP02080631 2002-12-20
EP02080631 2002-12-20
PCT/NL2003/000423 WO2003106691A1 (en) 2002-06-14 2003-06-13 POLYPEPTIDES HAVING α- H-α-AMINO ACID AMIDE RACEMASE ACTIVITY AND NUCLEIC ACIDS ENCODING THE SAME

Publications (2)

Publication Number Publication Date
DE60313866D1 true DE60313866D1 (de) 2007-06-28
DE60313866T2 DE60313866T2 (de) 2008-04-17

Family

ID=29737945

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60313866T Expired - Lifetime DE60313866T2 (de) 2002-06-14 2003-06-13 Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür

Country Status (9)

Country Link
US (1) US7371555B2 (de)
EP (1) EP1513946B1 (de)
JP (1) JP4402587B2 (de)
CN (1) CN100471950C (de)
AT (1) ATE362544T1 (de)
AU (1) AU2003238717A1 (de)
DE (1) DE60313866T2 (de)
ES (1) ES2285128T3 (de)
WO (1) WO2003106691A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050166498A1 (en) * 1999-12-17 2005-08-04 Oakey David D. Carpet tile with cutout section, method and apparatus for production and method of installation
CN102285893A (zh) * 2004-01-19 2011-12-21 帝斯曼知识产权资产管理有限公司 6-氨基己酸的生物化学合成
DE102004013842A1 (de) 2004-03-20 2005-10-13 Degussa Ag Nitrilhydratasen aus Metagenombibliotheken
EP2245137B1 (de) 2008-01-22 2017-08-16 Genomatica, Inc. Verfahren und organismen zur nutzung von synthesegas oder anderen gasförmigen kohlenstoffquellen und methanol
SI2262901T1 (sl) 2008-03-05 2019-02-28 Genomatica, Inc. Primarni alkohol producirajoči organizmi
EP2172545A1 (de) 2008-09-24 2010-04-07 DSM IP Assets B.V. Herstellung von gereinigter Peptid-Deformylase
WO2010068944A2 (en) 2008-12-12 2010-06-17 Celexion, Llc Biological synthesis of difunctional alkanes from carbohydrate feedstocks
US8404465B2 (en) 2009-03-11 2013-03-26 Celexion, Llc Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks
KR101950944B1 (ko) 2009-04-30 2019-02-21 게노마티카 인코포레이티드 1,3-부탄다이올 생산 유기체
WO2010127303A1 (en) 2009-04-30 2010-11-04 Genomatica, Inc. Organisms for the production of isopropanol, n-butanol, and isobutanol
WO2011017560A1 (en) 2009-08-05 2011-02-10 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
EP2491125A4 (de) 2009-10-23 2014-04-23 Genomatica Inc Mikroorganismen zur herstellung von anilin
BR112012018620A2 (pt) 2010-01-29 2015-09-15 Genomatica Inc organismo microbiano de ocorrência não-natural, método para produzir (2-hidroxi-3-metil-4-oxobutoxi) fosfonato, método para produção de p-toluato, método para produzir tereftalato
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
WO2012007548A1 (en) 2010-07-14 2012-01-19 Dsm Ip Assets B.V. (r)-selective amination
BR112013001635A2 (pt) 2010-07-26 2016-05-24 Genomatica Inc micro-organismo e métodos para a biossíntese de aromáticos, 2, 4-pentadienoato e 1,3-butadieno
CN109337832B (zh) * 2018-03-14 2021-06-15 重庆理工大学 一种耐高氨氮异养硝化-好氧反硝化的苍白杆菌及其应用
CN110317742B (zh) * 2019-03-22 2021-01-01 厦门大学 一株耐铬的石油烃降解菌株Tph3-32及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK261685A (da) * 1985-06-11 1986-12-12 Novo Industri As Fremgangsmaade til fremstilling af optisk aktive, organiske forbindelser
JPS63129984A (ja) * 1986-11-21 1988-06-02 Toray Ind Inc α−アミノ−ε−カプロラクタム・ラセマ−ゼ
EP0330695B1 (de) * 1987-08-17 1992-11-11 Novo Nordisk A/S Verfahren zur herstellung von organischen chemischen verbindungen
DE3816063A1 (de) * 1988-05-06 1989-11-23 Schering Ag Verfahren zur herstellung von l-aminosaeuren und aminosaeure-amiden
EP0383403A1 (de) * 1989-02-16 1990-08-22 Stamicarbon B.V. Verfahren zur Herstellung von organischen chemischen Produkten
NL9100038A (nl) * 1991-01-11 1992-08-03 Stamicarbon Enzym-gekatalyseerde bereiding van optisch aktieve carbonzuren.
AU4436900A (en) 1999-04-29 2000-11-17 Dsm N.V. Expression cassette for efficient production of a protein
JP4122416B2 (ja) 2004-02-24 2008-07-23 関西ティー・エル・オー株式会社 α−アミノ−ε−カプロラクタムラセマーゼを用いた、Ｄ及びＬ−アミノ酸アミドの混合物の製造方法、Ｄ又はＬ−アミノ酸の製造方法、Ｄ又はＬ−アミノ酸アミドの製造方法

Also Published As

Publication number Publication date
ES2285128T3 (es) 2007-11-16
AU2003238717A1 (en) 2003-12-31
CN1675371A (zh) 2005-09-28
EP1513946A1 (de) 2005-03-16
JP4402587B2 (ja) 2010-01-20
CN100471950C (zh) 2009-03-25
US7371555B2 (en) 2008-05-13
WO2003106691A1 (en) 2003-12-24
JP2005529611A (ja) 2005-10-06
EP1513946B1 (de) 2007-05-16
DE60313866T2 (de) 2008-04-17
US20040248274A1 (en) 2004-12-09
ATE362544T1 (de) 2007-06-15

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