DE60233589D1 - Verfahren zur herstellung von echinocandinderivaten - Google Patents

Verfahren zur herstellung von echinocandinderivaten

Info

Publication number
DE60233589D1
DE60233589D1 DE60233589T DE60233589T DE60233589D1 DE 60233589 D1 DE60233589 D1 DE 60233589D1 DE 60233589 T DE60233589 T DE 60233589T DE 60233589 T DE60233589 T DE 60233589T DE 60233589 D1 DE60233589 D1 DE 60233589D1
Authority
DE
Germany
Prior art keywords
echinocandine
derivatives
preparation
echinocandine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60233589T
Other languages
English (en)
Inventor
Philippe Boffelli
Agnes Brouillard
Colette Colladant
Serge Droux
Michel Elter
Didier Ferroud
Guy Lemaitre
Joseph Paladino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novexel SA
Original Assignee
Novexel SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novexel SA filed Critical Novexel SA
Application granted granted Critical
Publication of DE60233589D1 publication Critical patent/DE60233589D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE60233589T 2001-12-14 2002-12-12 Verfahren zur herstellung von echinocandinderivaten Expired - Lifetime DE60233589D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0116230A FR2833596B1 (fr) 2001-12-14 2001-12-14 Procede de preparation de derives d'echinocandine
PCT/FR2002/004308 WO2003054001A2 (fr) 2001-12-14 2002-12-12 Procede de preparation de derives d'echinocandines et leurs compositions

Publications (1)

Publication Number Publication Date
DE60233589D1 true DE60233589D1 (de) 2009-10-15

Family

ID=8870520

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60233589T Expired - Lifetime DE60233589D1 (de) 2001-12-14 2002-12-12 Verfahren zur herstellung von echinocandinderivaten

Country Status (29)

Country Link
US (3) US20070105760A1 (de)
EP (1) EP1456229B1 (de)
JP (1) JP4510461B2 (de)
KR (1) KR20040066167A (de)
CN (2) CN100584859C (de)
AR (1) AR037827A1 (de)
AT (1) ATE441662T1 (de)
AU (1) AU2002364991B9 (de)
BR (1) BR0214937A (de)
CA (1) CA2469918A1 (de)
CO (1) CO5590934A2 (de)
CY (1) CY1110694T1 (de)
DE (1) DE60233589D1 (de)
DK (1) DK1456229T3 (de)
EA (1) EA007964B1 (de)
ES (1) ES2333784T3 (de)
FR (1) FR2833596B1 (de)
HK (2) HK1071900A1 (de)
HU (1) HUP0402602A3 (de)
IL (1) IL162385A0 (de)
MX (1) MXPA04005484A (de)
NO (1) NO20042640L (de)
NZ (1) NZ533864A (de)
PL (1) PL371763A1 (de)
PT (1) PT1456229E (de)
SI (1) SI1456229T1 (de)
TW (1) TWI322820B (de)
WO (1) WO2003054001A2 (de)
ZA (1) ZA200404631B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
TW200826957A (en) * 2006-10-16 2008-07-01 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Purification processes for echinocandin-type compounds
FR2921060B1 (fr) * 2007-09-14 2012-06-15 Novexel Nouveau procede de preparation d'une piperidine disubsituee et nouveaux intermediaires
FR2936798B1 (fr) * 2008-10-03 2012-09-28 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens.
FR2936951B1 (fr) * 2008-10-10 2010-12-03 Novexel Nouvelles combinaisons de composes heterocycliques azotes antibacteriens avec d'autres composes antibacteriens et leur utilisation comme medicaments
FR2937034B1 (fr) * 2008-10-10 2012-11-23 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens
CN101928670B (zh) * 2009-09-24 2012-02-22 上海天伟生物制药有限公司 一种抗生素的高产菌株及其制备方法和用途
CN102659930B (zh) * 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102627688B (zh) * 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
WO2016056022A2 (en) * 2014-10-07 2016-04-14 Alaparthi Lakshmi Prasad Intermediates and processes to prepare anidulafungin
CN112646854B (zh) * 2020-12-11 2022-10-11 浙江工业大学 一种棘白菌素b合成培养基及应用
CN115785226A (zh) * 2021-09-09 2023-03-14 上海天伟生物制药有限公司 一种棘白菌素药物杂质及其制备、纯化方法和应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293484A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912H nucleus
US5207710A (en) * 1988-09-29 1993-05-04 Collagen Corporation Method for improving implant fixation
US5539122A (en) * 1989-05-23 1996-07-23 Abbott Laboratories Retroviral protease inhibiting compounds
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
NZ512085A (en) * 1992-03-19 2003-08-29 Lilly Co Eli Methods employing cyclic peptide antifungal agents
SI9420051A (en) * 1993-08-09 1996-12-31 Biomeasure Inc Chemical modified peptide derivatives, process for their preparation and their use in human therapy
JP3107691B2 (ja) * 1993-12-03 2000-11-13 株式会社東芝 半導体記憶装置及びその製造方法
EP0781141B1 (de) * 1994-09-16 2002-09-04 Merck & Co. Inc. Azazyklohexapeptid-verbindungen
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5852213A (en) * 1996-07-10 1998-12-22 American Cyanamid Company Mercaptoketones and mercaptoalcohols and a process for their preparation
US6207710B1 (en) * 1996-11-22 2001-03-27 Elan Pharmaceuticals, Inc. Compounds for inhibiting β-amyloid peptide release and/or its synthesis
UA72200C2 (uk) * 1997-12-10 2005-02-15 Авентіс Фарма С.А. Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція
FR2794746B1 (fr) * 1999-06-09 2002-12-06 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme anti-fongiques
FR2794747B1 (fr) * 1999-06-09 2004-04-16 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme anti-fongiques
AU6564000A (en) * 1999-07-27 2001-02-13 Aventis Pharma Deutschland Gmbh Novel cyclohexapeptide compounds, processes for their production and their use as a pharmaceutical
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine

Also Published As

Publication number Publication date
AR037827A1 (es) 2004-12-09
CN1604908A (zh) 2005-04-06
ATE441662T1 (de) 2009-09-15
CN1781938A (zh) 2006-06-07
HK1087720A1 (en) 2006-10-20
MXPA04005484A (es) 2004-12-06
EP1456229B1 (de) 2009-09-02
AU2002364991B2 (en) 2008-05-15
AU2002364991A1 (en) 2003-07-09
CN1326872C (zh) 2007-07-18
AU2002364991B9 (en) 2008-10-09
US7148322B2 (en) 2006-12-12
ES2333784T3 (es) 2010-03-01
CN100584859C (zh) 2010-01-27
PL371763A1 (en) 2005-06-27
DK1456229T3 (da) 2010-01-04
WO2003054001A2 (fr) 2003-07-03
US20070105760A1 (en) 2007-05-10
IL162385A0 (en) 2005-11-20
TWI322820B (en) 2010-04-01
CO5590934A2 (es) 2005-12-30
JP2005523245A (ja) 2005-08-04
EA007964B1 (ru) 2007-02-27
HK1071900A1 (en) 2005-08-05
HUP0402602A3 (en) 2012-06-28
TW200301133A (en) 2003-07-01
EA200400806A1 (ru) 2004-12-30
EP1456229A2 (de) 2004-09-15
US20100273977A1 (en) 2010-10-28
NO20042640L (no) 2004-06-23
HUP0402602A2 (hu) 2005-04-28
JP4510461B2 (ja) 2010-07-21
SI1456229T1 (sl) 2010-02-26
ZA200404631B (en) 2005-01-10
FR2833596A1 (fr) 2003-06-20
WO2003054001A3 (fr) 2004-01-22
NZ533864A (en) 2006-03-31
PT1456229E (pt) 2009-12-10
CY1110694T1 (el) 2015-06-10
BR0214937A (pt) 2004-12-14
US20050032679A1 (en) 2005-02-10
KR20040066167A (ko) 2004-07-23
CA2469918A1 (fr) 2003-07-03
FR2833596B1 (fr) 2005-02-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition