DE60232585D1 - Vorläuferzellpopulationen, deren expansion und die entstehung von nicht-hämatopoetischen zelltypen daraus - Google Patents

Vorläuferzellpopulationen, deren expansion und die entstehung von nicht-hämatopoetischen zelltypen daraus

Info

Publication number
DE60232585D1
DE60232585D1 DE60232585T DE60232585T DE60232585D1 DE 60232585 D1 DE60232585 D1 DE 60232585D1 DE 60232585 T DE60232585 T DE 60232585T DE 60232585 T DE60232585 T DE 60232585T DE 60232585 D1 DE60232585 D1 DE 60232585D1
Authority
DE
Germany
Prior art keywords
expansion
development
cell types
haematopoietic
progenitor cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60232585T
Other languages
English (en)
Inventor
Dolores Baksh
John E Davies
Peter Zandstra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60232585D1 publication Critical patent/DE60232585D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
DE60232585T 2001-04-24 2002-04-23 Vorläuferzellpopulationen, deren expansion und die entstehung von nicht-hämatopoetischen zelltypen daraus Expired - Lifetime DE60232585D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28570101P 2001-04-24 2001-04-24
US32811001P 2001-10-11 2001-10-11
PCT/CA2002/000550 WO2002086104A1 (en) 2001-04-24 2002-04-23 Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom

Publications (1)

Publication Number Publication Date
DE60232585D1 true DE60232585D1 (de) 2009-07-23

Family

ID=26963332

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60232585T Expired - Lifetime DE60232585D1 (de) 2001-04-24 2002-04-23 Vorläuferzellpopulationen, deren expansion und die entstehung von nicht-hämatopoetischen zelltypen daraus

Country Status (9)

Country Link
US (2) US20040137612A1 (de)
EP (2) EP2105497B1 (de)
JP (1) JP2004531256A (de)
AT (1) ATE433484T1 (de)
CA (2) CA2444959C (de)
DE (1) DE60232585D1 (de)
DK (2) DK2105497T3 (de)
ES (1) ES2328460T3 (de)
WO (1) WO2002086104A1 (de)

Families Citing this family (40)

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WO2002086104A1 (en) 2001-04-24 2002-10-31 Dolores Baksh Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom
US7807458B2 (en) 2003-01-30 2010-10-05 The United States Of America As Represented By The Secretary Of The Department Of Veterans Affairs Multilineage-inducible cells and uses thereof
ES2351386T3 (es) * 2003-02-11 2011-02-03 John E. Davies Células progenitoras procedentes de la gelatina de wharton de cordón umbilical humano .
WO2004097720A1 (en) * 2003-04-24 2004-11-11 Koninklijke Philips Electronics N.V. Non-invasive left ventricular volume determination
JP4604238B2 (ja) * 2003-09-19 2011-01-05 独立行政法人産業技術総合研究所 燐酸カルシウムと生理活性物質を含有する高分子複合体、その製造方法及びそれを用いた医療用材料
DK1725656T3 (da) 2004-03-05 2014-01-13 John E Davies Serumfri suspensionskultursystem til mesenchymale progenitorceller
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
WO2005108559A2 (en) * 2004-04-23 2005-11-17 Bioe, Inc. Multi-lineage progenitor cells
WO2009111390A1 (en) * 2008-03-03 2009-09-11 William Marsh Rice University Methods of fabricating enhanced tissue-engineered cartilage
CA2606081C (en) 2005-04-26 2013-09-17 Markus M. Heiss Combination of the application of antibodies for immunostimulation together with glucocorticoids
US20070042491A1 (en) * 2005-08-18 2007-02-22 Karp Jeffrey M Amplification of cell populations from embryonic stem cells
AU2006286149B2 (en) 2005-08-29 2012-09-13 Technion Research And Development Foundation Ltd. Media for culturing stem cells
EP1976980B1 (de) 2005-12-22 2019-03-06 Jane Ennis Lebensfähige zellen aus gefrorenem nabelschnurgewebe
ITTO20060282A1 (it) * 2006-04-14 2007-10-15 Univ Degli Studi Torino Mezzo di coltura e composizione farmaceutica per la rigenerazione del tessuto cartilagineo relativo procedimento relativi usi e prodotti
CA2646491A1 (en) * 2006-04-17 2007-10-25 Bioe, Inc. Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
ES2633939T3 (es) * 2006-05-05 2017-09-26 Tissue Regeneration Therapeutics Inc. Células progenitoras inmuno-privilegiadas y moduladoras
DK2046349T3 (en) * 2006-07-12 2015-12-21 Mesoblast Inc TREATMENT OF EXCESSIVE NEOVASCULARIZATION
DK3441459T3 (da) * 2006-08-02 2021-06-07 Technion Res & Dev Foundation Fremgangsmåder til ekspansion af embryonale stamceller i en suspensionskultur
WO2009015343A2 (en) * 2007-07-25 2009-01-29 Bioe, Inc. Differentiation of multi-lineage progenitor cells to chondrocytes
CA2721870C (en) 2008-04-21 2020-12-22 Tissue Regeneration Therapeutics, Inc. Genetically modified human umbilical cord perivascular cells for prophylaxis against or treatment of biological or chemical agents
EP2295537A4 (de) * 2008-05-14 2011-11-30 Public Univ Corp Yokohama City Menschliche leberstammzelle, verfahren zu ihrer herstellung, verfahren zur einleitung ihrer differenzierung und verfahren zu ihrer verwendung
EP2294187A2 (de) * 2008-05-21 2011-03-16 BioE LLC Differenzierung von mehrlinien-vorläuferzellen zu pankreaszellen
SG185526A1 (en) 2010-05-12 2012-12-28 Abt Holding Co Modulation of splenocytes in cell therapy
WO2012046065A2 (en) 2010-10-06 2012-04-12 Omnicyte Limited Culture method
WO2012048276A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
SG10201710638UA (en) 2013-04-12 2018-01-30 Saverio Lafrancesca Improving organs for transplantation
WO2015073918A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
CN106232800B (zh) 2014-03-25 2020-07-03 泰尔茂比司特公司 介质的被动替代
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
EP3242692A4 (de) * 2015-01-05 2018-09-05 Histogenics Corporation Neoknorpelkonstrukte mit universellen zellen
EP3098304A1 (de) 2015-05-28 2016-11-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Hybrides zellenablösungsfreies zellenerweiterungssystem für anklebende zellkultivierung und zugehöriges verfahrensprotokoll
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
WO2017127123A1 (en) 2016-01-21 2017-07-27 Abt Holding Company Stem cells for wound healing
KR102557574B1 (ko) * 2016-05-17 2023-07-20 엘지전자 주식회사 디지털 디바이스 및 그 제어 방법
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
CN110612344B (zh) 2017-03-31 2023-09-12 泰尔茂比司特公司 细胞扩增
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
WO2020061408A1 (en) * 2018-09-21 2020-03-26 Tarachon Llc Cartilage regeneration by synovial fluid-derived stem cells and their derivatives

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US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
US5837539A (en) * 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5197985A (en) * 1990-11-16 1993-03-30 Caplan Arnold I Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
US6010696A (en) * 1990-11-16 2000-01-04 Osiris Therapeutics, Inc. Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells
US5226914A (en) * 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
US5736396A (en) * 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US7514074B2 (en) * 1997-07-14 2009-04-07 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
EP1064356A2 (de) * 1998-03-23 2001-01-03 ZymoGenetics, Inc. Herz-derivierte stammzellen
CA2348687A1 (en) 1998-11-09 2000-05-18 Consorzio Per La Gestione Del Centro Di Biotecnologie Avanzate Serum free medium for chondrocyte-like cells
WO2001011011A2 (en) * 1999-08-05 2001-02-15 Mcl Llc Multipotent adult stem cells and methods for isolation
WO2002086104A1 (en) 2001-04-24 2002-10-31 Dolores Baksh Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom
KR100534215B1 (ko) 2003-11-11 2005-12-08 (주)히스토스템 냉동 보관된 제대혈로부터 중간엽 줄기세포의 분리 및 배양 방법

Also Published As

Publication number Publication date
EP2105497A1 (de) 2009-09-30
WO2002086104A1 (en) 2002-10-31
ES2328460T3 (es) 2009-11-13
US20080020459A1 (en) 2008-01-24
CA2444959A1 (en) 2002-10-31
US9644182B2 (en) 2017-05-09
CA2444959C (en) 2014-07-08
DK2105497T3 (da) 2019-06-24
EP2105497B1 (de) 2019-04-03
CA2843001A1 (en) 2002-10-31
EP1383869B1 (de) 2009-06-10
ATE433484T1 (de) 2009-06-15
EP1383869A1 (de) 2004-01-28
US20040137612A1 (en) 2004-07-15
DK1383869T3 (da) 2009-10-05
JP2004531256A (ja) 2004-10-14

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