DE29818721U1 - Injection device - Google Patents

Injection device

Info

Publication number
DE29818721U1
DE29818721U1 DE1998218721 DE29818721U DE29818721U1 DE 29818721 U1 DE29818721 U1 DE 29818721U1 DE 1998218721 DE1998218721 DE 1998218721 DE 29818721 U DE29818721 U DE 29818721U DE 29818721 U1 DE29818721 U1 DE 29818721U1
Authority
DE
Germany
Prior art keywords
injection device
housing
threaded rod
actuator
relative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1998218721
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
B D Medico Sarl Ch
Original Assignee
Medico Development Investment Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medico Development Investment Co filed Critical Medico Development Investment Co
Priority to DE1998218721 priority Critical patent/DE29818721U1/en
Priority to CA 2356614 priority patent/CA2356614A1/en
Priority to JP2000576905A priority patent/JP2002527210A/en
Priority to PCT/EP1999/007587 priority patent/WO2000023133A2/en
Priority to EP99953764A priority patent/EP1123124A2/en
Priority to DE1999148988 priority patent/DE19948988A1/en
Publication of DE29818721U1 publication Critical patent/DE29818721U1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/202—Having specific accessories cocking means, e.g. to bias the main drive spring of an injector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Loading And Unloading Of Fuel Tanks Or Ships (AREA)

Description

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßtThe description text was not recorded electronically

Claims (37)

1. Injektionsgerät mit einem Gehäuse (42),
welches zur Aufnahme eines Behälters (50) mit einer Flüssigkeit ausgebildet ist,
mit einem im Gehäuse (42) axial verschiebbar angeordneten Teil (92) zur Einwirkung auf diesen Behälter (50),
mit einem Stellglied (174) zur Beeinflussung der Lage des axial verschiebbaren Teils (92) relativ zu diesem Stellglied (174),
ferner mit einem im Gehäuse (42) axial verschiebbar, aber relativ zum Gehäuse (42) im wesentlichen unverdrehbar angeordneten Element (144),
wobei das Stellglied (174) relativ zu diesem Element (144) mindestens zwei verschiedene Stellungen einnehmen kann und in einer ersten dieser Stellungen (Fig. 12) relativ zu diesem Element (144) verdrehbar und in einer zweiten dieser Stellungen (Fig. 13) relativ zu diesem Element (144) unverdrehbar ist.1. injection device with a housing ( 42 ),
which is designed to hold a container ( 50 ) with a liquid,
with a part ( 92 ) axially displaceably arranged in the housing ( 42 ) for acting on this container ( 50 ),
with an actuator ( 174 ) for influencing the position of the axially displaceable part ( 92 ) relative to this actuator ( 174 ),
furthermore with an element ( 144 ) which is axially displaceable in the housing ( 42 ) but essentially non-rotatable relative to the housing ( 42 ),
wherein the actuator (174) can assume relative to this element (144) at least two different positions and relatively in a first of these positions (Fig. 12) relative to this element (144) rotatably and in a second of these positions (Fig. 13) to this element ( 144 ) is not rotatable. 2. Injektionsgerät nach Anspruch 1, bei welchem das Stellglied (174) in der zweiten Stellung (Fig. 13) mit dem axial verschiebbaren Element (144) verrastet ist, so daß es nur zusammen mit diesem bewegt werden kann.2. Injection device according to claim 1, wherein the actuator ( 174 ) in the second position ( Fig. 13) with the axially displaceable element ( 144 ) is locked so that it can only be moved together with this. 3. Injektionsgerät nach Anspruch 1 oder 2, bei welchem das im Gehäuse (42) axial verschiebbar angeordnete Teil als Gewindestange (92) ausgebildet ist, welche im Gehäuse (42) axial verschiebbar, aber relativ zum Gehäuse (42) unverdrehbar, geführt ist.3. Injection device according to claim 1 or 2, in which the part arranged axially displaceably in the housing ( 42 ) is designed as a threaded rod ( 92 ) which is axially displaceable in the housing ( 42 ) but non-rotatable relative to the housing ( 42 ). 4. Injektionsgerät nach Anspruch 3, bei welchem das Außengewinde (104) der Gewindestange (92) mit einem entsprechenden Innengewinde (Fig. 11: 184', 186') des Stellglieds (174) in Eingriff steht. 4. Injection device according to claim 3, wherein the external thread ( 104 ) of the threaded rod ( 92 ) with a corresponding internal thread ( Fig. 11: 184 ', 186') of the actuator ( 174 ) is engaged. 5. Injektionsgerät nach Anspruch 4, bei welchem das Außengewinde der Gewindestange (92) nach Art einer Zahnstange ausgebildet ist, und das Innengewinde (Fig. 11: 184', 186') des Stellglieds (174) zu diesem Außengewinde (104) im wesentlichen komplementär ausgebildet ist.5. Injection device according to claim 4, wherein the external thread of the threaded rod ( 92 ) is designed in the manner of a rack, and the internal thread ( Fig. 11: 184 ', 186') of the actuator ( 174 ) to this external thread ( 104 ) substantially is complementary. 6. Injektionsgerät nach Anspruch 4 oder 5, bei welchem das Innengewinde des Stellglieds (174) als Teilgewinde (Fig. 11: 184', 186') an wenigstens einem federnden Element (184, 186) des Stellglieds (174) ausgebildet ist, um eine Bewegung dieses federnden Elements (184, 186) quer zu den Zähnen der Gewindestange (92) zu ermöglichen.6. Injection device according to claim 4 or 5, wherein the internal thread of the actuator ( 174 ) is designed as a partial thread ( Fig. 11: 184 ', 186') on at least one resilient element ( 184 , 186 ) of the actuator ( 174 ) allow movement of this resilient element ( 184 , 186 ) transverse to the teeth of the threaded rod ( 92 ). 7. Injektionsgerät mit einem Gehäuse (42),
welches zur Aufnahme eines Behälters (50) mit einer Flüssigkeit ausgebildet ist, in welchem Behälter (50) ein Kolben (90) verschiebbar angeordnet ist,
mit einer Gewindestange (92) zum Bewegen dieses Kolbens (90), welche Gewindestange mit einem Außengewinde (104) versehen und im Gehäuse (42) axial verschiebbar, aber unverdrehbar, angeordnet ist,
mit einem Stellglied (174), welches mit einem Innengewinde (184', 186') zum Eingriff mit dem Außengewinde (104) der Gewindestange (92) versehen ist, um durch eine relative Verdrehung zwischen Stellglied (174) und Gewindestange (92) eine axiale Verschiebung der Gewindestange (92) zu ermöglichen,
wobei das Außengewinde (104) der Gewindestange (92) die Form von Zähnen einer Zahnstange aufweist, und das hierzu im wesentlichen komplementäre Innengewinde (184', 186') des Stellglieds (174) an mindestens einem federnden Element (184, 186) des Stellglieds (174) angeordnet ist,
um durch axiale Verschiebung des Stellglieds (174) relativ zur Gewindestange (92) ein Gleiten der Zähne dieses Innengewindes (184', 186') quer zu den Zähnen des Außengewindes (104) der Gewindestange (92) zu ermöglichen. 7. injection device with a housing ( 42 ),
which is designed to hold a container ( 50 ) with a liquid, in which container ( 50 ) a piston ( 90 ) is slidably arranged,
with a threaded rod ( 92 ) for moving this piston ( 90 ), which threaded rod is provided with an external thread ( 104 ) and is arranged in the housing ( 42 ) so as to be axially displaceable but non-rotatable,
with an actuator ( 174 ), which is provided with an internal thread ( 184 ', 186 ') for engagement with the external thread ( 104 ) of the threaded rod ( 92 ), by a relative rotation between the actuator ( 174 ) and the threaded rod ( 92 ) to allow axial displacement of the threaded rod ( 92 ),
wherein the external thread ( 104 ) of the threaded rod ( 92 ) has the form of teeth of a toothed rack, and the internal thread ( 184 ', 186 ') of the actuator ( 174 ), which is essentially complementary thereto, on at least one resilient element ( 184 , 186 ) of the actuator ( 174 ) is arranged,
to allow the teeth of this internal thread ( 184 ', 186 ') to slide across the teeth of the external thread ( 104 ) of the threaded rod ( 92 ) by axially displacing the actuator ( 174 ) relative to the threaded rod ( 92 ). 8. Injektionsgerät nach Anspruch 7, bei welchem die Gewindestange (92) an ihrem proximalen Ende (96) mit dem Kolben (90) verbunden ist, welcher in dem Behälter (50) verschiebbar angeordnet ist.8. Injection device according to claim 7, wherein the threaded rod ( 92 ) is connected at its proximal end ( 96 ) to the piston ( 90 ) which is arranged displaceably in the container ( 50 ). 9. Injektionsgerät nach Anspruch 7 oder 8, bei welchem die Zähne (104) der Gewindestange (92) im wesentlichen sägezahnförmig ausgebildet sind und im Querschnitt gesehen jeweils einen proximalen Abschnitt (106) mit geringer Steigung und einen distalen Abschnitt (108) mit großer Steigung aufweisen, um eine axiale Verschiebung zwischen Gewindestange (92) und Stellglied (174) nur in einer Richtung zu ermöglichen.9. Injection device according to claim 7 or 8, in which the teeth ( 104 ) of the threaded rod ( 92 ) are substantially sawtooth-shaped and, viewed in cross section, each have a proximal section ( 106 ) with a small pitch and a distal section ( 108 ) with a large pitch have in order to enable an axial displacement between the threaded rod ( 92 ) and the actuator ( 174 ) only in one direction. 10. Injektionsgerät nach einem oder mehreren der Ansprüche 7 bis 9, bei welchem das Stellglied (174) relativ zu einem Element (144), welches im Gehäuse (42) axial verschiebbar, aber unverdrehbar, angeordnet ist, mindestens zwei verschiedene Stellungen einnehmen kann, wobei das Stellglied (174) in einer dieser Stellungen (Fig. 12) relativ zu diesem Element (144) verdrehbar und in einer anderen dieser Stellungen (Fig. 13) relativ zu diesem Element (144) unverdrehbar ist.10. Injection device according to one or more of claims 7 to 9, in which the actuator ( 174 ) can assume at least two different positions relative to an element ( 144 ) which is arranged axially displaceably but non-rotatably in the housing ( 42 ), wherein the actuator to this element (174) in one of these positions (Fig. 12) relative (144) to rotate and in another of these positions (Fig. 13) relative to this element (144) non-rotatably. 11. Injektionsgerät nach Anspruch 10, bei welchem zwischen Stellglied (174) und im Gehäuse (42) axial verschiebbarem Element (144) mindestens ein Rastglied (170, 192', 194') vorgesehen ist, um eine Verrastung zwischen Stellglied (174) und diesem Element (144) in mindestens einer der genannten Stellungen zu ermöglichen.11. Injection device according to claim 10, in which between the actuator ( 174 ) and in the housing ( 42 ) axially displaceable element ( 144 ) at least one locking element ( 170 , 192 ', 194 ') is provided in order to lock between the actuator ( 174 ) and enable this element ( 144 ) in at least one of the positions mentioned. 12. Injektionsgerät nach Anspruch 10 oder 11, bei welchem ein Rastglied (170, 192', 194') zur Verrastung in der Stellung vorgesehen ist, in der das Stellglied (174) relativ zum im Gehäuse (42) axial verschiebbaren Element (144) nicht verdrehbar ist.12. Injection device according to claim 10 or 11, in which a latching member ( 170 , 192 ', 194 ') is provided for latching in the position in which the actuator ( 174 ) relative to the element ( 144 ) axially displaceable in the housing ( 42 ). is not rotatable. 13. Injektionsgerät nach einem oder mehreren der Ansprüche 7 bis 12, bei welchem der Flüssigkeitsbehälter (50) relativ zum Gehäuse (42) axial verschiebbar ist, um durch Verschieben des Flüssigkeitsbehälters (50) eine Einstichbewegung einer mit dem Flüssigkeitsbehälter (50) verbundenen Kanüle (250) in die Haut des Patienten zu ermöglichen.13. Injection device according to one or more of claims 7 to 12, wherein the liquid container (50) is axially displaceable relative to the housing (42) for a puncturing motion of a connected with the liquid container (50) cannula by moving the liquid container (50) ( 250 ) into the patient's skin. 14. Injektionsgerät nach Anspruch 13, bei welchem zwischen dem verschiebbaren Flüssigkeitsbehälter (50) und der Gewindestange (92) eine von der axialen Stellung des Flüssigkeitsbehälters (50) beeinflußte mechanische Verbindung (136, 137) vorgesehen ist.14. Injection device according to claim 13, wherein a mechanical connection ( 136 , 137 ) influenced by the axial position of the liquid container ( 50 ) is provided between the displaceable liquid container ( 50 ) and the threaded rod ( 92 ). 15. Injektionsgerät nach einem oder mehreren der Ansprüche 7 bis 14, welches einen Indikator (126) aufweist, der betätigt wird, wenn die Gewindestange (92) durch Drehen des Stellglieds (174) zuerst um einen vorgegebenen Wert in proximaler Richtung und anschließend um einen vorgegebenen Wert in distaler Richtung verschoben worden ist.15. Injection device according to one or more of claims 7 to 14, which has an indicator ( 126 ) which is actuated when the threaded rod ( 92 ) by rotating the actuator ( 174 ) first by a predetermined value in the proximal direction and then by one predetermined value has been shifted in the distal direction. 16. Injektionsgerät nach Anspruch 15, bei welchem in einer Ausnehmung (114) der Gewindestange (92) ein verschiebbares Glied (116) angeordnet ist, an dessen distalem Ende der Indikator (126) lösbar befestigt ist.16. Injection device according to claim 15, in which in a recess ( 114 ) of the threaded rod ( 92 ) a displaceable member ( 116 ) is arranged, at the distal end of which the indicator ( 126 ) is releasably attached. 17. Injektionsgerät nach Anspruch 16, bei welchem das verschiebbare Glied (116) ein Anschlagglied (118) aufweist, das bei einer proximalen Bewegung der Gewindestange (92) gegen einen Anschlag (Fig. 21: 104) stößt und dabei das verschiebbare Glied (116) aus einer ersten Raststellung (Fig. 5) in distaler Richtung in eine zweite Raststellung (Fig. 23) verschiebt, in der der Indikator (126) aktiviert wird.17. The injection device as claimed in claim 16, in which the displaceable member ( 116 ) has a stop member ( 118 ) which, when the threaded rod ( 92 ) moves proximally, abuts a stop ( FIG. 21: 104) and thereby the displaceable member ( 116 ) from a first locking position ( FIG. 5) in the distal direction into a second locking position ( FIG. 23), in which the indicator ( 126 ) is activated. 18. Injektionsgerät nach einem oder mehreren der vorhergehenden Ansprüche, mit einer Feder (20) zum Speichern von Energie für eine Injektion, welche Feder (200) durch Verschieben eines Spannglieds (144) in distaler Richtung spannbar ist, und mit einem Rastglied (156, 158) zum lösbaren Verrasten des Spannglieds (144) in dieser verschobenen Stellung.18. Injection device according to one or more of the preceding claims, with a spring ( 20 ) for storing energy for an injection, which spring ( 200 ) can be tensioned in the distal direction by displacing a tensioning element ( 144 ), and with a locking element ( 156 , 158 ) for releasably latching the tendon ( 144 ) in this displaced position. 19. Injektionsgerät nach Anspruch 18, bei welchem im Gehäuse (42) Nocken (140, 142) vorgesehen sind, welche in der verschobenen Stellung des Spannglieds (144) eine lageabhängige mechanische Verbindung (136, 137) zwischen Gewindestange (92) und Flüssigkeitsbehälter (50) aktivieren.19. Injection device according to claim 18, in which in the housing ( 42 ) cams ( 140 , 142 ) are provided which, in the displaced position of the tensioning member ( 144 ), a position-dependent mechanical connection ( 136 , 137 ) between the threaded rod ( 92 ) and the liquid container ( 50 ) activate. 20. Injektionsgerät nach einem oder mehreren der vorhergehenden Ansprüche, bei welchem dem Flüssigkeitsbehälter (50) ein Halter (74) zugeordnet ist, welcher im Gehäuse (42) axial zwischen einer proximalen und einer distalen Endstellung verschiebbar ist und zur Aufnahme des Flüssigkeitsbehälters (50) ausgebildet ist.20. Injection device according to one or more of the preceding claims, in which the liquid container ( 50 ) is assigned a holder ( 74 ) which is axially displaceable in the housing ( 42 ) between a proximal and a distal end position and for receiving the liquid container ( 50 ) is trained. 21. Injektionsgerät nach Anspruch 20, bei welchem die Länge des Halters (74) veränderbar ist.21. Injection device according to claim 20, wherein the length of the holder ( 74 ) is variable. 22. Injektionsgerät nach Anspruch 21, bei welchem der Halter (74) einen proximalen Abschnitt (76) und einen distalen Abschnitt (78) aufweist, welche durch eine verstellbare Verbindung (77) miteinander verbunden sind, die eine Änderung der Gesamtlänge des Halters (74) ermöglicht.22. The injection device according to claim 21, wherein the holder ( 74 ) has a proximal section ( 76 ) and a distal section ( 78 ), which are connected to one another by an adjustable connection ( 77 ), which change the total length of the holder ( 74 ) enables. 23. Injektionsgerät nach Anspruch 22, bei welchem die verstellbare Verbindung eine Mikrorastung (77) aufweist, welche einen proximalen Abschnitt (76) und einen distalen Abschnitt (78) des Halters (74) in verstellbarer Weise miteinander verbindet.23. The injection device according to claim 22, wherein the adjustable connection has a micro-catch ( 77 ) which connects a proximal section ( 76 ) and a distal section ( 78 ) of the holder ( 74 ) to one another in an adjustable manner. 24. Injektionsgerät nach einem oder mehreren der Ansprüche 20 bis 23, bei welchem der Halter (74) in seinem distalen Bereich mit Anschlagmitteln (80) versehen ist, welche seine proximale und/oder seine distale Endstellung relativ zum Gehäuse (42) festlegen, und bei welchem die Längenverstellung des Halters (74) relativ zu diesen Anschlagmitteln erfolgt, so daß bei einer Längenänderung des Halters (74) die Lage des Flüssigkeitsbehälters (50) relativ zur Gewindestange (92) verändert wird.24. Injection device according to one or more of claims 20 to 23, in which the holder ( 74 ) is provided in its distal region with stop means ( 80 ) which fix its proximal and / or its distal end position relative to the housing ( 42 ), and in which the length of the holder ( 74 ) is adjusted relative to these stop means, so that when the holder ( 74 ) changes in length, the position of the liquid container ( 50 ) relative to the threaded rod ( 92 ) is changed. 25. Injektionsgerät nach einem oder mehreren der vorhergehenden Ansprüche, bei welchem ein relativ zum Gehäuse (42) in Längsrichtung verschiebbares Dosiseinstellteil (58) Rastmittel (66) zur Verrastung eines Rastorgans (158) aufweist. 25. Injection device according to one or more of the preceding claims, in which a dose setting part ( 58 ) which is displaceable in the longitudinal direction relative to the housing ( 42 ) has latching means ( 66 ) for latching a latching member ( 158 ). 26. Injektionsgerät nach Anspruch 25, bei welchem am verschiebbaren Dosiseinstellteil (58) ein Glied (62) zum Lösen der Rastung zwischen den Rastmitteln (66) und dem Rastorgan (158) vorgesehen ist.26. Injection device according to claim 25, in which a link ( 62 ) for releasing the latching between the latching means ( 66 ) and the latching member ( 158 ) is provided on the displaceable dose setting part ( 58 ). 27. Injektionsgerät nach Anspruch 25 oder 26, bei welchem am Gehäuse (42) eine relativ zu diesem verdrehbare aber relativ zum ihm nicht axial verschiebbare Gewindehülse (52) vorgesehen ist, welche mit einem Gewinde (56) am verschiebbaren Dosiseinstellteil (58) in Eingriff steht.27. Injection device according to claim 25 or 26, in which on the housing ( 42 ) is rotatable relative to this but not axially displaceable relative to it threaded sleeve ( 52 ) is provided, which with a thread ( 56 ) on the displaceable dose setting part ( 58 ) in engagement stands. 28. Injektionsgerät nach einem oder mehreren der Ansprüche 25 bis 27, bei welchem das verschiebbare Dosiseinstellteil (58) relativ zum Gehäuse (42) nicht verdrehbar ist.28. Injection device according to one or more of claims 25 to 27, in which the displaceable dose setting part ( 58 ) cannot be rotated relative to the housing ( 42 ). 29. Adapter zur Befestigung eines mit einer Gummimembran (233) versehenen Behälters (224) an einem Injektionsgerät,
mit einem Gehäuse (212),
mit einer in diesem Gehäuse (212) angeordneten Kanüle (218), die sich sowohl in Richtung zum Injektionsgerät (40) wie in Richtung zum Behälter (224) erstreckt und an einem Kanülenträger (216) befestigt ist,
mit einem am einen Endbereich des Kanülenträgers (216) vorgesehenen Innengewinde (217) zur Befestigung an einem Außengewinde des Injektionsgeräts (40),
und mit einer am entgegengesetzten Endbereich des Gehäuses (212) vorgesehenen Aufnahme (228) für den Teil (227) des Behälters, der mit der Gummimembran (233) versehen ist (Fig. 16, 17).29. adapter for fastening a container ( 224 ) provided with a rubber membrane ( 233 ) to an injection device,
with a housing ( 212 ),
with a cannula ( 218 ) arranged in this housing ( 212 ), which extends both in the direction of the injection device ( 40 ) and in the direction of the container ( 224 ) and is fastened to a cannula carrier ( 216 ),
with an internal thread ( 217 ) provided on one end region of the cannula carrier ( 216 ) for attachment to an external thread of the injection device ( 40 ),
and with a receptacle ( 228 ) provided on the opposite end region of the housing ( 212 ) for the part ( 227 ) of the container which is provided with the rubber membrane ( 233 ) ( FIGS. 16, 17). 30. Adapter nach Anspruch 29, bei welchem die am entgegengesetzten Endbereich des Gehäuses (212) vorgesehene Aufnahme (228) mit einem radial nach innen ragenden Rastvorsprung (230) versehen ist, um den Behälter (224) im Gehäuse (212) des Adapters verrasten zu können.30. The adapter of claim 29, wherein the receptacle ( 228 ) provided on the opposite end region of the housing ( 212 ) is provided with a radially inwardly projecting locking projection ( 230 ) in order to lock the container ( 224 ) in the housing ( 212 ) of the adapter to be able to. 31. Adapter nach Anspruch 29 oder 30, bei welchem im entgegengesetzten Endbereich ein von der Kanüle (218) perforierbares Teil (222) verschiebbar angeordnet ist.31. An adapter according to claim 29 or 30, in which a part ( 222 ) which can be perforated by the cannula ( 218 ) is slidably arranged in the opposite end region. 32. Adapter nach Anspruch 31, bei welchem das von der Kanüle (218) perforierbare Teil (222) im Zustand vor der Perforation (Fig. 16) das zugeordnete Ende der Kanüle (218) steril abdeckt.32. Adapter according to claim 31, in which the part ( 222 ) perforable by the cannula ( 218 ) in the state before the perforation ( FIG. 16) covers the associated end of the cannula ( 218 ) in a sterile manner. 33. Adapter nach einem oder mehreren der vorhergehenden Ansprüche, bei welchem der eine Endbereich (217) des Gehäuses (212) steril abgedeckt ist.33. Adapter according to one or more of the preceding claims, wherein the one end region ( 217 ) of the housing ( 212 ) is covered in a sterile manner. 34. Adapter nach Anspruch 33, bei welchem zwischen dem Kanülenträger (216) und dem rohrartigen Gehäuse (212) ein Halter (214) für den Kanülenträger (216) vorgesehen ist, und die sterile Abdeckung (220) an einem Ende dieses Halters (214) vorgesehen ist.34. An adapter according to claim 33, in which a holder ( 214 ) for the cannula holder ( 216 ) is provided between the cannula holder ( 216 ) and the tubular housing ( 212 ), and the sterile cover ( 220 ) at one end of this holder ( 214 ) is provided. 35. Adapter nach Anspruch 33 oder 34, bei welchem zur sterilen Abdeckung eine Peelfolie (220) oder dgl. vorgesehen ist.35. Adapter according to claim 33 or 34, in which a peel film ( 220 ) or the like is provided for sterile covering. 36. Adapter nach einem oder mehreren der Ansprüche 29 bis 35, bei welchem das Gehäuse (212) durch den Kanülenträger (216) in Teilbereiche unterteilt ist, welche über die Kanüle (218) miteinander in Flüssigkeitsverbindung stehen.36. Adapter according to one or more of claims 29 to 35, in which the housing ( 212 ) is subdivided by the cannula carrier ( 216 ) into partial areas which are in fluid communication with one another via the cannula ( 218 ). 37. Adapter nach einem oder mehreren der Ansprüche 29 bis 36, bei welchem der Kanülenträger (216) und die Kanüle (218) im wesentlichen als Standardbauteil ausgebildet sind, wie es für Injektionen mit üblichen Injektionsgeräten verwendet wird.37. Adapter according to one or more of claims 29 to 36, in which the cannula carrier ( 216 ) and the cannula ( 218 ) are designed essentially as a standard component, as is used for injections with conventional injection devices.
DE1998218721 1998-10-21 1998-10-21 Injection device Expired - Lifetime DE29818721U1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE1998218721 DE29818721U1 (en) 1998-10-21 1998-10-21 Injection device
CA 2356614 CA2356614A1 (en) 1998-10-21 1999-10-09 Method for reconstituting an injection fluid, and injection apparatus for implementing said method
JP2000576905A JP2002527210A (en) 1998-10-21 1999-10-09 Method for reconstituting an injection and an injection device for carrying out such a method
PCT/EP1999/007587 WO2000023133A2 (en) 1998-10-21 1999-10-09 Method for reconstituting an injection fluid, and injection apparatus for implementing said method
EP99953764A EP1123124A2 (en) 1998-10-21 1999-10-09 Method for reconstituting an injection fluid, and injection apparatus for implementing said method
DE1999148988 DE19948988A1 (en) 1998-10-21 1999-10-12 Injection unit accepting liquid container includes locking system with two settings, first selected for use by doctor or nurse and second for patient who cannot return to first position, as safety measure

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DE1999148988 Withdrawn DE19948988A1 (en) 1998-10-21 1999-10-12 Injection unit accepting liquid container includes locking system with two settings, first selected for use by doctor or nurse and second for patient who cannot return to first position, as safety measure

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US9352097B2 (en) 2009-06-01 2016-05-31 Sanofi-Aventis Deutschland Gmbh Spindle for a drug delivery device
US9408978B2 (en) 2009-06-01 2016-08-09 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism for priming a drug delivery device
US9457150B2 (en) 2009-06-01 2016-10-04 Sanofi-Aventis Deutschland Gmbh Biasing mechanism for a drug delivery device
US9463283B2 (en) 2009-06-01 2016-10-11 Sanofi-Aventis Deutschland Gmbh Dosing mechanism for a drug deliver device
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US11654243B2 (en) 2009-06-01 2023-05-23 Sanofi-Aventis Deutschland Gmbh Inner housing for a drug delivery device
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US9950116B2 (en) 2009-06-01 2018-04-24 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism for priming a drug delivery device
US10034982B2 (en) 2009-06-01 2018-07-31 Sanofi-Aventis Deutschland Gmbh Spindle for a drug delivery device
US10195354B2 (en) 2009-06-01 2019-02-05 Sanofi-Aventis Deutschland Gmbh Resettable drug delivery device
US10279116B2 (en) 2009-06-01 2019-05-07 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism for priming a drug delivery device
US10391254B2 (en) 2009-06-01 2019-08-27 Sanofi-Aventis Deutschland Gmbh Inner housing for a drug delivery device
US11559628B2 (en) 2009-06-01 2023-01-24 Sanofi-Aventis Deutschland Gmbh Drug delivery device inner housing having helical spline
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WO2000023133A3 (en) 2000-08-10
EP1123124A2 (en) 2001-08-16
JP2002527210A (en) 2002-08-27
CA2356614A1 (en) 2000-04-27
DE19948988A1 (en) 2000-04-27

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