DE19841385A1 - Use of creatine and/or creatine derivatives as moisturizers in cosmetic compositions - Google Patents
Use of creatine and/or creatine derivatives as moisturizers in cosmetic compositionsInfo
- Publication number
- DE19841385A1 DE19841385A1 DE1998141385 DE19841385A DE19841385A1 DE 19841385 A1 DE19841385 A1 DE 19841385A1 DE 1998141385 DE1998141385 DE 1998141385 DE 19841385 A DE19841385 A DE 19841385A DE 19841385 A1 DE19841385 A1 DE 19841385A1
- Authority
- DE
- Germany
- Prior art keywords
- creatine
- use according
- preparations
- derivatives
- moisturizers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
Abstract
Description
Gegenstand der vorliegenden Erfindung ist die Verwendung von Kreatin und/oder Kreatin-Derivaten als Feuchthaltemittel (Moisturizer) in kosmetischen Zubereitungen.The subject of the present invention is the use of creatine and / or creatine derivatives as humectants (moisturizers) in cosmetic preparations.
Zubereitungen in creme-, gel- oder flüssiger Form, die zu kosmetischen Zwecken topisch, daneben aber auch oral und dann systemisch angewendet werden können, beinhalten in den meisten Fällen Feuchthaltemittel, die sog. Moisturizer. Mit Hilfe dieser Feuchthaltemittel wird zum einen eine anhaltend stabile Konsistenz und Anwendbarkeit der jeweiligen Kosmetika gewährleistet, was insbesondere bei den unterschiedlichsten Cremes wichtig ist. Zum anderen tragen die Feuchthaltemittel auch zu einem gewissen Wohlbefinden aufgrund des kühlenden Effektes bei, die von den diversen Creme- und Gelzubereitungen bei deren Anwendung ausgehen.Preparations in cream, gel or liquid form which are too cosmetic Topical, but also oral and then systemic can be applied in most cases Humectants, the so-called moisturizers. With the help of these humectants on the one hand, a persistently stable consistency and applicability of the particular cosmetics ensures, especially in the case of different creams is important. On the other hand, the wear Humectants also contribute to a sense of well-being due to the Cooling effect of the various cream and Gel preparations go out in their application.
Ziel der allermeisten kosmetischen Zubereitungen ist eine positive Einflußnahme auf den Zustand und das Aussehen der Haut.The goal of most cosmetic preparations is a positive one Influence on the condition and appearance of the skin.
Mit zunehmenden Alter verändert sich nämlich der kolloidale Zustand der Eiweißkörper, bspw. des Kollagens derart, daß die Wasserbindungsfähigkeit abnimmt und der Gewebsturgor verringert wird. Ein Folge davon sind atrophische Veränderungen, was sich insbesondere in einer vermehrten Faltenbildung und einer gesteigerten Trockenheit insbesondere der oberen Hautschichten, wie des Stratum corneum äußert. Die mit diesen Veränderungen einhergehenden vermehrten Symptome, wie Schuppenbildung, führen insgesamt zu einem verschlechterten Aussehen der Hautoberfläche.With increasing age, namely, the colloidal state of the Eiweißkörper, eg. The collagen such that the Water binding ability decreases and the tissue sturgeon is reduced. One consequence of this is atrophic changes, especially in an increased wrinkling and increased dryness especially the upper skin layers, as the stratum corneum expresses. The increased symptoms associated with these changes, such as dandruff, overall, lead to a worsening Appearance of the skin surface.
Die Hautoberfläche wird aber nicht nur durch Alterungsprozesse verändert, sondern auch durch eine Reihe äußerer Einflüsse. So verursachen generell Umwelteinflüsse und die Witterung, aber auch extremes Waschen und Entfetten der Haut, wie z. B. der häufige Gebrauch von Lösemitteln, eine verstärkte Austrocknung der Haut mit Rißbildung und Schuppung. Dabei können sich altersbedingte und durch äußere Einflüsse verursachte Veränderungen der Haut addieren.The skin surface is not only due to aging processes changed, but also through a series of external influences. So generally cause environmental influences and the weather, as well extreme washing and degreasing of the skin, such as B. the frequent use of solvents, an increased drying of the skin with cracking and scaling. This can be due to age and by external Influences caused by skin changes add up.
Um diesen sich an der Oberfläche der Haut abspielenden Prozessen entgegenzuwirken, verfügt die Haut von Natur aus über Mechanismen, die man als Natural Moisturizing Faktoren bezeichnet. Bekannte Vertreter dieser Faktoren sind Harnstoff und bestimmte Aminosäuren wie Glycin und Arginin, die natürlicherweise auf der Hautoberfläche angetroffen werden.Around these processes that play on the surface of the skin By nature, the skin naturally has mechanisms that one calls natural moisturizing factors. Well-known representatives These factors include urea and certain amino acids such as glycine and Arginine, which is found naturally on the skin surface.
Diese natürlich vorkommenden Stoffe werden in modernen Hautpflegemitteln - wie bereits erwähnt - durch die sogenannten Moisturizer unterstützt. Diese z. T. synthetischen Feuchthaltemittel wie Polyole, Glycerin, Sorbit, ethoxylierte Phenole und hydrolysierte Proteine können altersbedingte und/oder durch äußere Einflüsse bedingte Hautrauhigkeiten in dem Sinn günstig beeinflussen, daß die Haut eine glattere und geschmeidigere Oberfläche erhält.These naturally occurring substances are used in modern day Skin care products - as already mentioned - by the so-called Moisturizer supported. This z. T. synthetic moisturizers such as Polyols, glycerine, sorbitol, ethoxylated phenols and hydrolyzed proteins can be age-related and / or due to external influences Skin roughness in the sense favorably affect the skin gets smoother and smoother surface.
Nachteilig bei zahlreichen synthetischen Feuchthaltemitteln ist deren vielfach vor allem über längere Zeiträume hinweg mangelnde Stabilität, was insbesondere bei extremen Temperaturen zum Brechen der Emulsionen führt, was sich insbesondere auf cremeartige O/W-Emulsionen negativ auswirkt.A disadvantage of many synthetic humectants is their often lack of stability, especially over long periods of time, which especially at extreme temperatures to break the Emulsions, resulting in particular creamy O / W emulsions has a negative effect.
Es hat sich somit die Aufgabe gestellt, ein Feuchthaltemittel (Moisturizer) für kosmetische Zubereitungen bereitzustellen, das stabile Zubereitungen gewährleistet, natürlichen Ursprungs oder naturidentisch ist, darüber hinaus leicht zugänglich ist und das aufgrund seiner Zusammensetzung keine gesundheitlichen Nebenwirkungen erwarten läßt.It has thus set itself the task of a humectant (moisturizer) for cosmetic preparations, the stable preparations guaranteed, of natural origin or nature-identical, about it It is also easily accessible due to its composition no health effects expected.
Gelöst wurde diese Aufgabe durch die entsprechende Verwendung von Kreatin und/oder Kreatin-derivaten.This task was solved by the appropriate use of Creatine and / or creatine derivatives.
Überraschend konnte beim praktischen Einsatz von Kreatin bzw. dessen geeigneter Derivate festgestellt werden, daß entsprechend der Aufgabenstellung nicht nur die gewünschten stabilen kosmetischen Zubereitungen erhalten werden, sondern daß auch die Symptome einer trockenen Haut, wie Risse und Schuppung, nachhaltig beseitigt werden konnten oder diesen Phänomenen sogar vorgebeugt werden konnte. Außerdem kann durch die erfindungsgemäße Verwendung auch der körpereigene Energiehaushalt in dem Sinn positiv beeinflußt werden, daß auch tiefere Unterhautschichten eine andauernde Straffung erfahren, was in diesem Ausmaß so nicht vorhersehbar war.Surprising was the practical use of creatine or its appropriate derivatives are found that according to the Task not only the desired stable cosmetic Preparations are obtained, but that the symptoms of a Dry skin, such as cracks and scaling, can be permanently eliminated could even prevent these phenomena. In addition, the inventive use of the the body's energy balance are positively influenced in the sense that even deeper subcutaneous layers undergo a lasting tightening, which in so unforeseeable.
Kreatin ist eine natürliche, als bekannter Energiespeicher vor allem im Muskelgewebe vorkommende Verbindung, die nicht toxisch ist, von den Nieren zum harngängigen Kreatinin katabolisiert wird, und darüber hinaus lokal eine sehr gute Verträglichkeit aufweist, wie experimentelle Untersuchungen gezeigt haben. Von Kreatin ist ebenfalls bekannt, daß es pro Gramm 23 ml Wasser zu binden vermag (vgl. Neumann: Creatinabol- Studie).Creatine is a natural, known energy storage especially in the Muscle tissue occurring compound that is non-toxic, from the Kidneys are catabolized to urinary creatinine, and beyond locally has a very good compatibility, such as experimental Studies have shown. Creatine is also known to be can bind 23 ml of water per gram (see Neumann: Creatinabol- Study).
Besonders geeignet im Sinn der vorliegenden Erfindung hat sich das Kreatin-monohydrat erwiesen; aber auch Kreatin-Derivate bspw. in Salzform, wie das bevorzugte Kreatin-ascorbat sind sehr gut geeignet. Dabei können alle geeigneten Kreatin-Derivate auch als Mischungen untereinander verwendet werden, aber auch gemeinsam mit weiteren geeigneten Feuchthaltemitteln, wie bspw. den bekannten natürlichen "moisturizing" Faktoren.Particularly suitable in the sense of the present invention, the Creatine monohydrate proved; but also creatine derivatives, for example, in Salt form, such as the preferred creatine ascorbate are very well suited. All suitable creatine derivatives can also be used as mixtures be used among each other, but also together with others suitable humectants, such as, for example, the known natural "moisturizing" factors.
Als besonders interessant hat sich die Verwendung von Kreatin(-derivaten) als Feuchthaltemittel in kosmetischen Zubereitungen erwiesen, da mit den geeigneten Kreatin-Verbindungen additive z. T. aber auch synergistische Wirkungen erreicht werden können.Particularly interesting has been the use of creatine (derivatives) as humectant in cosmetic preparations, since with the suitable creatine compounds additive z. T. but also synergistic Effects can be achieved.
Für diese speziellen Anwendungsfälle sieht die Erfindung vor, das Kreatin und/oder dessen geeignete Derivate vorzugsweise in Cremes, wie Tages- und Nachtcremes, gelartigen oder flüssigen Zubereitungen zu verwenden, wobei sich bei letzteren besonders bevorzugt um Gesichtswässer, Lotionen und Suspensionen handelt. For these specific applications, the invention provides creatine and / or its suitable derivatives, preferably in creams, such as and night creams, to use gel or liquid preparations, the latter particularly preferably being face lotions, lotions and suspensions.
In diesen Fällen einer rein äußerlichen Anwendung empfiehlt sich die erfindungsgemäße Verwendung der Kreatin-Komponente(n) vorzugsweise in Mengen von 0,5 bis 10 Gew.-% und besonders bevorzugt in einer Menge von 1 bis 5 Gew.-%, jeweils bezogen auf die Gesamtzubereitung.In these cases of a purely external application is recommended Use of the creatine component (s) according to the invention preferably in amounts of 0.5 to 10 wt .-% and particularly preferably in an amount from 1 to 5 wt .-%, each based on the total preparation.
Die vorliegende Erfindung sieht aber auch eine orale Verabreichung der Kreatin-enthaltenden Zubereitungen vor. Die bevorzugten Zubereitungsformen, denen weitere Feuchthaltemittel natürlich fehlen, wie Pulver, Dragees, Tabletten, Pastillen, Kapseln oder Flüssigkeiten, sollten dabei die Aufnahme der Kreatin-Komponente in einer Menge erlauben, die eine Tagesdosis von 10 g nicht überschreitet; empfohlen wird eine Tagesdosis von ca. 5 g.However, the present invention also provides for oral administration of the Creatine-containing preparations. The preferred ones Forms of preparation, which other moisturizers are naturally absent, such as Powders, dragees, tablets, lozenges, capsules or liquids should allow the intake of the creatine component in an amount that does not exceed a daily dose of 10 g; recommended is a Daily dose of about 5 g.
Das Spektrum der erfindungsgemäßen Verwendung geeigneter Kreatin- Komponenten erweitert sich hinsichtlich der äußeren und inneren Anwendung auch durch die Möglichkeit, den Zubereitungen weitere physiologisch aktive Bestandteile zuzusetzen, was die Erfindung ebenfalls berücksichtigt. Besonders geeignet sind natürlich Antioxidantien wie bspw. die Ascorbinsäure, Vitamine wie das α-Tocopherol-acetat, Spurenelemente, aber auch Sonnenschutzmittel.The spectrum of the use according to the invention of suitable creatine Components expand in terms of the outer and inner Application also by the possibility of further preparations to add physiologically active ingredients, which the invention also considered. Of course, particularly suitable are antioxidants such as. ascorbic acid, vitamins such as α-tocopherol acetate, trace elements, but also sunscreen.
Insgesamt zeigt die erfindungsgemäße Verwendung von Kreatin und/oder dessen Derivate, daß bei oraler Aufnahme der entsprechenden kosmetischen Zubereitungen innerhalb des Körpers, vor allem aber in den tieferen Schichten der Haut, Wasser gespeichert wird, wodurch besonders bestehende Falten geglättet werden können und einer neuerlichen Faltenbildung vorgebeugt werden kann. Bei lokaler und meist oberflächlicher Anwendung der Kreatin-haltigen Zubereitungen wird insbesondere das Hauptphänomen der trockenen Haut, die Hautschuppung zurückgedrängt und die oberflächliche Faltenbildung vermieden. Overall, the inventive use of creatine and / or its derivatives that when ingested the corresponding cosmetic preparations within the body, but especially in the deeper layers of the skin, water is stored, which makes it especially existing wrinkles can be smoothed and a renewed Wrinkling can be prevented. At local and mostly superficial application of creatine-containing preparations especially the main phenomenon of dry skin, dandruff pushed back and superficial wrinkles avoided.
Die entsprechend formulierten Kreatin-haltigen Zubereitungen verbessern vor allem die elastischen Eigenschaften, insbesondere der strapazierten Haut, nachhaltig, was sie für zahlreiche kosmetische Anwendungen geeignet macht, die auch über die traditionellen Felder der Hautkosmetik hinausgehen können, bspw. in Shampoos, Haar-, Mund- und Gurgelwässern, Lippenstiften, Make-up-Formulierungen, Hand- und Fußbädern sowie Abdeckcremes usw.Improve the appropriately formulated creatine-containing preparations especially the elastic properties, especially the strained Skin, lasting, what they do for numerous cosmetic applications which also makes the traditional fields of skin cosmetics can go out, for example, in shampoos, hair, mouth and Gurgelwässern, lipsticks, make-up formulations, hand and Foot baths as well as cover creams etc.
Claims (10)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1998141385 DE19841385A1 (en) | 1998-09-10 | 1998-09-10 | Use of creatine and/or creatine derivatives as moisturizers in cosmetic compositions |
PCT/EP1999/006670 WO2000015187A1 (en) | 1998-09-10 | 1999-09-09 | Creatine and/or creatine derivatives used as cosmetic preparations containing moisturizers |
GB0108722A GB2357970A (en) | 1998-09-10 | 1999-09-09 | Creatine and/or creatine derivatives used as cosmetic preparations containing moisturizers |
JP2000569772A JP2002524486A (en) | 1998-09-10 | 1999-09-09 | Cosmetic composition containing creatine and / or creatine derivative as humectant |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1998141385 DE19841385A1 (en) | 1998-09-10 | 1998-09-10 | Use of creatine and/or creatine derivatives as moisturizers in cosmetic compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
DE19841385A1 true DE19841385A1 (en) | 2000-03-16 |
Family
ID=7880498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1998141385 Withdrawn DE19841385A1 (en) | 1998-09-10 | 1998-09-10 | Use of creatine and/or creatine derivatives as moisturizers in cosmetic compositions |
Country Status (4)
Country | Link |
---|---|
JP (1) | JP2002524486A (en) |
DE (1) | DE19841385A1 (en) |
GB (1) | GB2357970A (en) |
WO (1) | WO2000015187A1 (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002002075A1 (en) * | 2000-07-06 | 2002-01-10 | Beiersdorf Ag | Use of creatine and/or creatine derivatives in cosmetic or dermatological preparations |
WO2002060394A2 (en) * | 2001-02-02 | 2002-08-08 | Coty B.V. | Revitalising active complex for the skin |
WO2002076408A2 (en) | 2001-03-24 | 2002-10-03 | Wella Aktiengesellschaft | Use of creatine, creatinine and/or derivatives thereof |
WO2003005988A1 (en) * | 2001-07-07 | 2003-01-23 | Beiersdorf Ag | Cosmetic and dermatological preparations containing creatine for treating and actively preventing dry skin and other negative alterations of the physiological homeostasis of healthy skin |
WO2003011242A1 (en) * | 2001-07-25 | 2003-02-13 | Beiersdorf Ag | Cosmetic or dermatological preparations containing a combination of creatinine and/or creatinine derivatives and creatine and/or the derivatives thereof |
WO2003011241A1 (en) * | 2001-07-25 | 2003-02-13 | Beiersdorf Ag | Utilization of creatinine and/or creatinine derivatives in cosmetic and dermatological preparations |
WO2004064801A1 (en) * | 2003-01-17 | 2004-08-05 | Beiersdorf Ag | Cosmetic or dermatological preparations containing creatine, creatinine and/or the derivatives thereof combined with soya bean extracts |
DE102004009962A1 (en) * | 2004-03-01 | 2005-09-22 | Degussa Ag | Use of guanidine compounds as physiological restorative in the form of nutritional supplements, feed additives, in cosmetic preparations and as plant strengthening agents |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6242491B1 (en) | 1999-06-25 | 2001-06-05 | Rima Kaddurah-Daouk | Use of creatine or creatine compounds for skin preservation |
DE10003835A1 (en) * | 2000-01-28 | 2001-08-16 | Sueddeutsche Kalkstickstoff | Formulations in dehydration conditions |
DE10119608A1 (en) * | 2001-04-21 | 2002-10-24 | Goldschmidt Ag Th | Hair treatment or post-treatment compositions for preventing or repairing damage caused by chemical treatment, e.g. perming or bleaching, containing creatine or its derivative as hair strengthening agent |
ATE300280T1 (en) * | 2002-02-15 | 2005-08-15 | Goldschmidt Gmbh | USE OF CREATININE AND/OR CREATININE DERIVATIVES TO BRIGHTEN THE SKIN AND REDUCE PIGMENT DISORDERS |
DE10355714A1 (en) * | 2003-11-26 | 2005-06-30 | Beiersdorf Ag | Active ingredient combination of creatine and / or creatinine, phenoxyethanol and, if desired, glycerol |
DE10355716A1 (en) | 2003-11-26 | 2005-06-23 | Beiersdorf Ag | Cosmetic preparations containing creatine and / or creatine derivatives and / or creatinine and / or creatinine derivatives and organic thickeners |
JP5756614B2 (en) * | 2010-11-02 | 2015-07-29 | 花王株式会社 | Autoinducer-2 inhibitor and preventive and / or therapeutic agent for caries disease |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5091171B2 (en) * | 1986-12-23 | 1997-07-15 | Tristrata Inc | Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use |
FR2725896B1 (en) * | 1994-10-19 | 1996-11-29 | Sederma Sa | NEW COSMETIC OR DERMOPHARMACEUTICAL COMPOSITIONS |
JPH09202710A (en) * | 1995-11-20 | 1997-08-05 | Kao Corp | Wrinkles improver |
US5939078A (en) * | 1995-11-20 | 1999-08-17 | Kao Corporation | Wrinkle-care product |
-
1998
- 1998-09-10 DE DE1998141385 patent/DE19841385A1/en not_active Withdrawn
-
1999
- 1999-09-09 GB GB0108722A patent/GB2357970A/en not_active Withdrawn
- 1999-09-09 JP JP2000569772A patent/JP2002524486A/en active Pending
- 1999-09-09 WO PCT/EP1999/006670 patent/WO2000015187A1/en active Application Filing
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10032964B4 (en) * | 2000-07-06 | 2017-10-12 | Beiersdorf Ag | Use of creatine in cosmetic or dermatological preparations |
EP2218480A3 (en) * | 2000-07-06 | 2011-01-26 | Beiersdorf AG | Use of creatine and/or creatine derivatives in cosmetic or dermatological preparations |
EP1642559A3 (en) * | 2000-07-06 | 2009-05-06 | Beiersdorf AG | Use of creatine and/or creatine derivatives in cosmetic or dermatological preparations |
EP1642559A2 (en) * | 2000-07-06 | 2006-04-05 | Beiersdorf AG | Use of creatine and/or creatine derivatives in cosmetic or dermatological preparations |
WO2002002075A1 (en) * | 2000-07-06 | 2002-01-10 | Beiersdorf Ag | Use of creatine and/or creatine derivatives in cosmetic or dermatological preparations |
WO2002060394A3 (en) * | 2001-02-02 | 2003-04-03 | Coty Bv | Revitalising active complex for the skin |
WO2002060394A2 (en) * | 2001-02-02 | 2002-08-08 | Coty B.V. | Revitalising active complex for the skin |
WO2002076408A3 (en) * | 2001-03-24 | 2003-04-10 | Wella Ag | Use of creatine, creatinine and/or derivatives thereof |
US7687055B2 (en) | 2001-03-24 | 2010-03-30 | Wella Ag | Method of treating keratinic fibers with creatine, creatinine and/or their salts to strengthen, restructure, harden and stabilize them |
WO2002076408A2 (en) | 2001-03-24 | 2002-10-03 | Wella Aktiengesellschaft | Use of creatine, creatinine and/or derivatives thereof |
WO2003005988A1 (en) * | 2001-07-07 | 2003-01-23 | Beiersdorf Ag | Cosmetic and dermatological preparations containing creatine for treating and actively preventing dry skin and other negative alterations of the physiological homeostasis of healthy skin |
DE10136077A1 (en) * | 2001-07-25 | 2003-02-13 | Beiersdorf Ag | Cosmetic or dermatological preparations containing creatinine and creatine, useful e.g. for combating skin aging symptoms or treating inflammatory conditions such as eczema or psoriasis |
WO2003011241A1 (en) * | 2001-07-25 | 2003-02-13 | Beiersdorf Ag | Utilization of creatinine and/or creatinine derivatives in cosmetic and dermatological preparations |
WO2003011242A1 (en) * | 2001-07-25 | 2003-02-13 | Beiersdorf Ag | Cosmetic or dermatological preparations containing a combination of creatinine and/or creatinine derivatives and creatine and/or the derivatives thereof |
WO2004064801A1 (en) * | 2003-01-17 | 2004-08-05 | Beiersdorf Ag | Cosmetic or dermatological preparations containing creatine, creatinine and/or the derivatives thereof combined with soya bean extracts |
DE102004009962A1 (en) * | 2004-03-01 | 2005-09-22 | Degussa Ag | Use of guanidine compounds as physiological restorative in the form of nutritional supplements, feed additives, in cosmetic preparations and as plant strengthening agents |
Also Published As
Publication number | Publication date |
---|---|
WO2000015187A1 (en) | 2000-03-23 |
JP2002524486A (en) | 2002-08-06 |
GB0108722D0 (en) | 2001-05-30 |
GB2357970A (en) | 2001-07-11 |
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Legal Events
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8110 | Request for examination paragraph 44 | ||
8127 | New person/name/address of the applicant |
Owner name: GOLDSCHMIDT AG, 45127 ESSEN, DE |
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8130 | Withdrawal |