DE1962331C3 - Wound dressing material - Google Patents
Wound dressing materialInfo
- Publication number
- DE1962331C3 DE1962331C3 DE1962331A DE1962331A DE1962331C3 DE 1962331 C3 DE1962331 C3 DE 1962331C3 DE 1962331 A DE1962331 A DE 1962331A DE 1962331 A DE1962331 A DE 1962331A DE 1962331 C3 DE1962331 C3 DE 1962331C3
- Authority
- DE
- Germany
- Prior art keywords
- collagen
- wound dressing
- dressing material
- wound
- nonwoven
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000463 material Substances 0.000 title claims description 15
- 102000008186 Collagen Human genes 0.000 claims description 32
- 108010035532 Collagen Proteins 0.000 claims description 32
- 229920001436 collagen Polymers 0.000 claims description 32
- 239000000835 fiber Substances 0.000 claims description 18
- 239000004745 nonwoven fabric Substances 0.000 claims description 6
- 239000012815 thermoplastic material Substances 0.000 claims description 2
- 239000010410 layer Substances 0.000 claims 2
- 239000011229 interlayer Substances 0.000 claims 1
- 206010052428 Wound Diseases 0.000 description 20
- 208000027418 Wounds and injury Diseases 0.000 description 20
- 230000002745 absorbent Effects 0.000 description 5
- 239000002250 absorbent Substances 0.000 description 5
- 239000004753 textile Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 150000001299 aldehydes Chemical class 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 229920001169 thermoplastic Polymers 0.000 description 3
- 239000004416 thermosoftening plastic Substances 0.000 description 3
- 229920000297 Rayon Polymers 0.000 description 2
- 206010048629 Wound secretion Diseases 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 229920002994 synthetic fiber Polymers 0.000 description 2
- 239000012209 synthetic fiber Substances 0.000 description 2
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 239000002649 leather substitute Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 239000002964 rayon Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/12—Layered products comprising a layer of synthetic resin next to a fibrous or filamentary layer
-
- A—HUMAN NECESSITIES
- A22—BUTCHERING; MEAT TREATMENT; PROCESSING POULTRY OR FISH
- A22C—PROCESSING MEAT, POULTRY, OR FISH
- A22C13/00—Sausage casings
- A22C13/0013—Chemical composition of synthetic sausage casings
- A22C13/0016—Chemical composition of synthetic sausage casings based on proteins, e.g. collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/01—Non-adhesive bandages or dressings
- A61F13/01008—Non-adhesive bandages or dressings characterised by the material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
- A61L15/325—Collagen
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B1/00—Layered products having a non-planar shape
- B32B1/08—Tubular products
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
- B32B27/304—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers comprising vinyl halide (co)polymers, e.g. PVC, PVDC, PVF, PVDF
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
- B32B5/02—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer
- B32B5/022—Non-woven fabric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
- B32B5/22—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed
- B32B5/24—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed one layer being a fibrous or filamentary layer
- B32B5/26—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed one layer being a fibrous or filamentary layer another layer next to it also being fibrous or filamentary
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
- D04H1/4282—Addition polymers
- D04H1/4291—Olefin series
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
- D04H1/4326—Condensation or reaction polymers
- D04H1/4334—Polyamides
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/58—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by applying, incorporating or activating chemical or thermoplastic bonding agents, e.g. adhesives
- D04H1/587—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by applying, incorporating or activating chemical or thermoplastic bonding agents, e.g. adhesives characterised by the bonding agents used
-
- D—TEXTILES; PAPER
- D21—PAPER-MAKING; PRODUCTION OF CELLULOSE
- D21F—PAPER-MAKING MACHINES; METHODS OF PRODUCING PAPER THEREON
- D21F11/00—Processes for making continuous lengths of paper, or of cardboard, or of wet web for fibre board production, on paper-making machines
- D21F11/14—Making cellulose wadding, filter or blotting paper
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00727—Plasters means for wound humidity control
- A61F2013/00731—Plasters means for wound humidity control with absorbing pads
- A61F2013/00744—Plasters means for wound humidity control with absorbing pads containing non-woven
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2262/00—Composition or structural features of fibres which form a fibrous or filamentary layer or are present as additives
- B32B2262/02—Synthetic macromolecular fibres
- B32B2262/0253—Polyolefin fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2262/00—Composition or structural features of fibres which form a fibrous or filamentary layer or are present as additives
- B32B2262/06—Vegetal fibres
- B32B2262/062—Cellulose fibres, e.g. cotton
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2305/00—Condition, form or state of the layers or laminate
- B32B2305/10—Fibres of continuous length
- B32B2305/20—Fibres of continuous length in the form of a non-woven mat
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2439/00—Containers; Receptacles
- B32B2439/70—Food packaging
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2597/00—Tubular articles, e.g. hoses, pipes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31855—Of addition polymer from unsaturated monomers
- Y10T428/31935—Ester, halide or nitrile of addition polymer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
- Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
- Y10T442/2762—Coated or impregnated natural fiber fabric [e.g., cotton, wool, silk, linen, etc.]
- Y10T442/277—Coated or impregnated cellulosic fiber fabric
- Y10T442/2787—Coating or impregnation contains a vinyl polymer or copolymer
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Textile Engineering (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Vascular Medicine (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Mechanical Engineering (AREA)
- Nonwoven Fabrics (AREA)
- Materials For Medical Uses (AREA)
- Laminated Bodies (AREA)
Description
Die Erfindung betrifft ein Wundauflagenmaterial aus Vliesstoff, dessen Eigenschaften gegenüber den herkömmüchen Textil-Wundverbänden wesentlich verbessert ist.The invention relates to a wound dressing material made from Non-woven fabric, the properties of which are significantly improved compared to conventional textile wound dressings is.
Es ist bekannt, Wunden mit Textilauflagen abzudekken. Derartige Auflagen werden heute fast ausschließlich verwendet. Eine einwandfreie Wundauflage muß mehrere Bedingungen erfüllen. So darf keine Reizung der Wunde eintreten, der Verband bzw. die Auflage darf nicht durch Verkrusten an der Wunde verkleben und keinen Wärmestau verursachen. Bei hoher Festigkeit ist eine ebenfalls hohe Saugfähigkeit erwünscht. Die gebräuchlichen Textil-Wundverbände und Wundauflagematerialien erfüllen diese Forderungen jedoch nur teilweise.It is known to cover wounds with textile coverings. Such requirements are almost exclusively today used. A perfect wound dressing must meet several conditions. So there must be no irritation enter the wound, the dressing or the pad must not stick to the wound with encrustation and do not cause heat build-up. With high strength, a high absorbency is also desirable. the Customary textile wound dressings and wound dressing materials only meet these requirements partially.
Der Erfindung liegt nun die Aufgabe zugrunde, ein Wundauflagematerial zu entwickeln, welches die vorstehend genannten Bedingungen vollständig erfüllt und überdies leicht zu handhaben ist.The invention is now based on the object of developing a wound dressing material which has the above mentioned conditions are fully met and, moreover, is easy to handle.
Es wird ein Wundauflagematerial vorgeschlagen, welches aus mindestens einer Vliesstoffbahn besteht und dadurch gekennzeichnet, ist, daß die Vliesstoffbahn *5 bzw. Vliesstoffbahnen mit Kollagen gebunden ist bzw. sind und die Konzentration des Kollagens über den Gesamtquerschnitt der Bahn hinweg zunimmt.A wound dressing material is proposed which consists of at least one nonwoven web and characterized in that the nonwoven web * 5 or nonwoven webs are bound with collagen and the concentration of collagen over the Total cross-section of the web away increases.
Das Binden von Faservliesen mit Kollagen ist an sich bereits bekannt. Man verwendet zu diesem Zwecke eine kollagenfasernhaltige Suspension bzw. einen Kollagcn-Faserbrci (collagen slurry). Das lose Faservlies wird mit diesem Kollagen-Faserbrei imprägniert, getrocknet und einer geeigneten Nachbehandlung unterworfen. Die so hergestellten Vlisstoffe werden z. B. als Syntheseleder verarbeitet. Entsprechende Verfahren sind in der Literatur beschrieben, z. B. in »The Journal of the American Leather Chemists Association«, Vol. LXIII, Nr. 1, Januar 1968 sowie den US-Patentschriften 3063892, 3071483, 3073714, 3233551, 3269851, < >o 32 85 775, 32 94 579. 32 94 581 und dem kanadischen Patent 7 49 911.The binding of nonwovens with collagen is already known per se. One uses a for this purpose suspension containing collagen fibers or a collagen fiber brci (collagen slurry). The loose fiber fleece is with this collagen pulp is impregnated, dried and subjected to a suitable aftertreatment. The so manufactured non-woven fabrics are z. B. processed as synthetic leather. Corresponding procedures are in the Literature described, e.g. B. in "The Journal of the American Leather Chemists Association", Vol. LXIII, No. 1, January 1968 and U.S. Patents 3063892, 3071483, 3073714, 3233551, 3269851, < > o 32 85 775, 32 94 579. 32 94 581 and the Canadian Patent 7 49 911.
Die bekannten Materialien zeichnen sich durch eine möglichst gleichförmige Verteilung von Fasern und Bindemittel (Kollagen) aus. Die Herstellungsverfahren hr> sind diesem Ziel angepaßt.The known materials are characterized by a distribution of fibers and binding agent (collagen) that is as uniform as possible. The manufacturing process hr> are adapted to this goal.
Von diesen bekannten kollagengebundenen Faservliesen unterscheidet sich das erfindungsgemäße Wundauflagematerial dadurch, daß es von einer Seite ausgehend mit Kollagen angereichert ist, wobei die Konzentration des Kollagens über den Gesamtquerschnitt der Bahn hinweg zunimmt.The wound dressing material according to the invention differs from these known collagen-bonded fiber webs in that it is enriched with collagen starting from one side, the The concentration of collagen increases over the entire cross-section of the web.
Es wurde gefunden, daß die Auflage wundfreundlicher wird, wenn der Kollagengehalt in Richtung der Wunde ansteigt. Vermutlich beruht diese Tatsache darauf, daß das Kollagen und die Wundränder einen vergleichbaren chemischen Aufbau besitzen.It has been found that the pad becomes more wound-friendly when the collagen content goes in the direction of Wound increases. Presumably this fact is due to the fact that the collagen and the wound edges are one have a comparable chemical structure.
Eine bevorzugte Ausführung des erfindungsgemäßen Wundauflagenmaterials besteht darin, daß zwei kollagengebundene Vliesstoffbahnen mit der angebenen Kollagenverteilung zusammen mit einer hochsaugfähigen Faserzwischenschicht vorgesehen sind, wobei die kollagenangereicherten Seiten der kollagengebundenen Vliesstoffbahnen außen angeordnet sind. In vielen Fällen ist es erwünscht, daß die drei Lagen punkt- oder linienförmig miteinander verschweißt sind. Hier-cj ist es erforderlich, daß wenigstens die Faserzwischenschicht ein pulverförmiges thermoplastisches Material enthält.A preferred embodiment of the wound dressing material according to the invention consists in that two collagen-bound Nonwoven webs with the specified collagen distribution together with a highly absorbent Fiber intermediate layer are provided, with the collagen-enriched sides being the collagen-bound Nonwoven webs are arranged outside. In many cases it is desirable that the three layers point or are linearly welded together. Here-cj it is required that at least the intermediate fiber layer contains a powdered thermoplastic material.
Zur Herstellung des erfindungsgemäßen Wundmaterials wird ein Fasergemisch z. B. aus gleichen Teilen Zellwolle und Zellulose in einem großen Wasserüberschuß aufgeschlämmt. Das Wasser enthält gleichzeitig den Kollagen-Faserbrei. Das Gemisch wird dann auf einem Steilsieb angeschwemmt. Auf dem Sieb sammelt sich ein Faservliesgemisch mit einem Anteil von etwa 5 bis 10 % Kollagen an, je nach der zugegebenen Menge Fasern. Am oberen Ende des Steilsicbes befindet sich ein weiterer Behälter mit einer Kollagendispersion. Diese Dispersion wird auf das darunterliegende Sieb mit dem abgelegten Vlies aufgebracht, wobei sich das Kollagen an der Oberfläche des bereits kollagenhaltigen Vlieses anreichert. Der Wasserüberschuß wird in üblicher Weise abgesaugt.To produce the wound material according to the invention, a fiber mixture is used, for. B. from equal parts Spun rayon and cellulose slurried in a large excess of water. The water contains at the same time the collagen pulp. The mixture is then washed ashore on a steep sieve. Collects on the sieve a fiber fleece mixture with a proportion of about 5 to 10% collagen, depending on the amount added Fibers. At the upper end of the steep sicbe there is another container with a collagen dispersion. This dispersion is applied to the sieve underneath with the laid fleece, whereby the Collagen accumulates on the surface of the already collagen-containing fleece. The excess water is in usually sucked off.
Das nasse Vlies wird anschließend getrocknet, indem es entweder durch eine Trockenkammer läuft oder über einen Trockenzylinder geführt wird. Hierbei tritt gleichzeitig eine Verfestigung des Materials ein.The wet fleece is then dried by either running it through a drying chamber or over it a drying cylinder is guided. At the same time, the material solidifies.
Das in dem Vlies vorhandene Kollagen kann anschließend noch gegerbt werden. Zu diesem Zweck wird das mit Kollagen verfestigte Faservlies mit einer wäßrigen. Aldehyde enthaltenden Lösung besprüht. Als Aldehyd eignet sich insbesondere Glutaraldehyd. Durch den Aldehyd wird das Kollagen gegerbt.The collagen present in the fleece can then be tanned. To this end the fiber fleece that has been consolidated with collagen is treated with an aqueous. Sprayed solution containing aldehydes. as Aldehyde is particularly suitable for glutaraldehyde. The collagen is tanned by the aldehyde.
Zur Herstellung des verschweißbaren Wundauflagematerials kann der Aufschlämmung der Textil- und Kollagenfasern in einem Überschuß von Wasser noch geringe Mengen, d.h. bis zu 10 % bezogen auf das Gewicht des Endproduktes, eines an uch bekannten thermoplastischen Pulvers, z. B. Polyvinylacetat, zugesetzt werden. Der fertige Vliesstoff kann dann in üblicher Weise, z. D. längs bestimmter Linien, thermisch verschweißt werden. Es ist so auf einfache und rationelle Weise möglich Tupfer und Saugkissen od. dgl. herzustellen. Bei Verwendung von zwei Vliesstofflagen, welche thermoplastisches Pulver enthalten, werden die Lagen so angeordnet, daß sich die kollagenarmen Flächen berühren bzw. die kollagenangereicherten Seiten nach außen zeigen.To produce the weldable wound dressing material, the slurry of the textile and collagen fibers in an excess of water can still be small amounts, ie up to 10% based on the weight of the end product, of a thermoplastic powder known from uch, e.g. B. polyvinyl acetate, may be added. The finished nonwoven fabric can then in the usual way, for. D. be thermally welded along certain lines. It is thus possible in a simple and rational way to produce swabs and absorbent pads or the like. When using two non-woven fabric layers which contain thermoplastic powder, the layers are arranged in such a way that the collagen-poor surfaces touch one another or the collagen-enriched sides point outwards.
Wie bereits erwähnt* ist es vielfach zweckmäßig, zwischen den beiden kollagenhaltigen Vliesstofflagcn noch eine weitere Lage aus hochsaugfähigen reinen Fasern anzuordnen. Das Dreischichtengebilde kann an den Rändern im Hochfrequenz- oder Wärmeimpulsverfahren verschweißt werden. Es erweicht hierbei das in den beiden äußeren Schichten vorhandene thermoplastische Pulver. Es ergibt sich ein fester Verbund allerAs already mentioned * it is often useful to place between the two collagen-containing nonwoven layers to arrange yet another layer of highly absorbent pure fibers. The three-layer structure can the edges are welded using high frequency or thermal impulse processes. It softens the in thermoplastic powders present on the two outer layers. There is a solid association of all
Schichten.Layers.
Wird ein quadratisches Dreischichtengebilde der vorstehend definierten Art an den Rändern verschweißt, so entsteht ein Wundkissen, das auf beiden Seiten wegen des hohen Kollagengehaltes dsir Außenflächen sehr wundfreundlich ist und außerdem durch die innen angeordnete hochsaugfähige Viieseinlage große Mengen an Wundsekreten aufzusaugen vermag.If a square three-layer structure of the type defined above is welded at the edges, the result is a wound pillow that has a high collagen content on both sides of the outer surface is very wound-friendly and is also large thanks to the highly absorbent Viieseinlage arranged on the inside Can absorb quantities of wound secretions.
Die Wahl der Fasern für die äußeren Schichten und auch für die innere Schicht kann weitgehend demThe choice of fibers for the outer layers and also for the inner layer can largely be the same
jeweiligen Einsatz angepaßt werden. So empfiehlt es sich häufig, bei den äußeren Schichten anstelle der üblichen Viskosefasern Synthesefasern, z, B, Polypropylenfasern, vorzusehen. Hierdurch wird eine bessere Festigkeit und eine verbesserte Durchlässigkeit des Wundsekrets zu der saugfähigen Innenschicht erzielt, weil Synthesefasern unter den angegebenen Bedingungen im Gebrauch fast nicht quellen und damit die hei der Herstellung gewählte Porosität des Materials auch :.m Gebrauch bei stark nässenden Wunden beibehalten.be adapted to the respective application. It is often advisable to use synthetic fibers, e.g. polypropylene fibers, instead of the usual viscose fibers for the outer layers. In this way, a better strength and improved permeability of the wound secretion is achieved with the absorbent inner layer, because synthetic fibers almost not swell under the conditions indicated in the use and thus the hot selected manufacture porosity of the material also: maintaining .m use with highly exuding wounds.
Claims (3)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1962331A DE1962331C3 (en) | 1969-12-12 | 1969-12-12 | Wound dressing material |
NL7012818A NL166403C (en) | 1969-12-12 | 1970-08-28 | WELDED CUSHION. |
CH129371A CH513595A (en) | 1969-12-12 | 1970-09-02 | Nonwoven fabrics with collagen bound - fibres |
CH1308270A CH509806A (en) | 1969-12-12 | 1970-09-02 | Wound dressing material |
US3728207D US3728207A (en) | 1969-12-12 | 1970-11-12 | Non-woven fabric |
FR7043272A FR2068808B1 (en) | 1969-12-12 | 1970-12-01 | |
BE759688D BE759688A (en) | 1969-12-12 | 1970-12-01 | NON WOVEN ETOFFE, ITS MANUFACTURING PROCESS AND NEW APPLICATIONS OF THIS ETOFFE |
JP10886970A JPS4944756B1 (en) | 1969-12-12 | 1970-12-08 | |
GB5874570A GB1335547A (en) | 1969-12-12 | 1970-12-10 | Non-woven fabrics |
GB5874470A GB1333602A (en) | 1969-12-12 | 1970-12-10 | Non-woven fabrics |
AT1117670A AT313477B (en) | 1969-12-12 | 1970-12-11 | Collagen-containing wound dressing |
AT103373A AT319724B (en) | 1969-12-12 | 1970-12-11 | Sausage casing |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1962331A DE1962331C3 (en) | 1969-12-12 | 1969-12-12 | Wound dressing material |
Publications (3)
Publication Number | Publication Date |
---|---|
DE1962331A1 DE1962331A1 (en) | 1971-06-24 |
DE1962331B2 DE1962331B2 (en) | 1978-03-09 |
DE1962331C3 true DE1962331C3 (en) | 1978-11-02 |
Family
ID=5753668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1962331A Expired DE1962331C3 (en) | 1969-12-12 | 1969-12-12 | Wound dressing material |
Country Status (9)
Country | Link |
---|---|
US (1) | US3728207A (en) |
JP (1) | JPS4944756B1 (en) |
AT (2) | AT319724B (en) |
BE (1) | BE759688A (en) |
CH (1) | CH509806A (en) |
DE (1) | DE1962331C3 (en) |
FR (1) | FR2068808B1 (en) |
GB (1) | GB1333602A (en) |
NL (1) | NL166403C (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3974319A (en) * | 1974-02-04 | 1976-08-10 | Nylonge Corporation | All purpose wipe material |
ZA774782B (en) * | 1976-08-19 | 1979-03-28 | Colgate Palmolive Co | Absorbent article |
AT356285B (en) * | 1977-06-30 | 1980-04-25 | Bunzl & Biach Ag | FABRIC |
DE3124028A1 (en) * | 1981-06-19 | 1982-12-30 | Naturin-Werk Becker & Co, 6940 Weinheim | DOUBLE-LAYERED SAUSAGE CASE MADE FROM AN OUTER TEXTILE FABRIC AND AN INTERNAL COLLAGEN COATING AND METHOD FOR THE PRODUCTION THEREOF AND THE USE OF THIS SAUSAGE CASE OF RAW AND BREAD SAUSAGE |
DE3526394A1 (en) * | 1985-07-24 | 1987-02-05 | Becker & Co Naturinwerk | RAW SAUSAGE SLEEVE, METHOD FOR THE PRODUCTION AND USE OF SAUSAGE PRODUCTS RIPING IN THE AIR |
DE3912693A1 (en) * | 1989-04-18 | 1990-10-25 | Bioprotan Handels Gmbh | Cosmetic preparations contg. water soluble collagen (deriv.) - applied as layer to support web e.g. for use as face mask |
US5383896A (en) * | 1993-05-25 | 1995-01-24 | Gershony; Gary | Vascular sealing device |
US6017359A (en) | 1993-05-25 | 2000-01-25 | Vascular Solutions, Inc. | Vascular sealing apparatus |
US5868778A (en) * | 1995-10-27 | 1999-02-09 | Vascular Solutions, Inc. | Vascular sealing apparatus and method |
US5569207A (en) * | 1994-10-13 | 1996-10-29 | Quinton Instrument Company | Hydrocolloid dressing |
US5554106A (en) * | 1994-10-13 | 1996-09-10 | Quinton Instrument Company | Hydrocolloid exit site dressing |
US6156677A (en) * | 1998-03-25 | 2000-12-05 | Kimberly-Clark Worldwide, Inc. | Cellulose-Based medical packaging material sterilizable by oxidizing gas plasma |
DE20000887U1 (en) | 2000-01-19 | 2001-06-07 | Riesinger Geb Dahlmann | Collection bag with suction device |
CN104007040B (en) * | 2014-06-05 | 2016-05-18 | 广州纺织服装研究院有限公司 | A kind of method that detects collagen content in cover type collagen modification fabric |
CN106309150B (en) * | 2015-06-29 | 2020-10-30 | 烟台蓝创生物技术有限公司 | Medical collagen dressing and preparation method and application thereof |
ES2842501T5 (en) | 2015-09-21 | 2023-04-13 | Modern Meadow Inc | Fiber Reinforced Fabric Composite Materials |
US11542374B2 (en) | 2016-02-15 | 2023-01-03 | Modern Meadow, Inc. | Composite biofabricated material |
US20190024303A1 (en) * | 2017-07-18 | 2019-01-24 | Modern Meadow, Inc. | Biofabricated leather articles, and methods thereof |
AU2018253595A1 (en) | 2017-11-13 | 2019-05-30 | Modern Meadow, Inc. | Biofabricated leather articles having zonal properties |
CN113286864A (en) | 2019-01-17 | 2021-08-20 | 现代牧场股份有限公司 | Layered collagen material and preparation method thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1421732A (en) * | 1963-12-24 | 1965-12-17 | Johnson & Johnson | Absorbent product and its manufacturing process |
IL23096A (en) * | 1964-03-31 | 1968-11-27 | Usm Corp | Manufacture of strong fibrous material |
FR1500852A (en) * | 1964-09-10 | 1968-01-24 | ||
US3523536A (en) * | 1966-02-26 | 1970-08-11 | Johnson & Johnson | Absorbent fibrous products |
DE1635500A1 (en) * | 1967-12-27 | 1972-05-18 | Freudenberg Carl | Process for the production of synthetic shoe upper leather |
-
1969
- 1969-12-12 DE DE1962331A patent/DE1962331C3/en not_active Expired
-
1970
- 1970-08-28 NL NL7012818A patent/NL166403C/en not_active IP Right Cessation
- 1970-09-02 CH CH1308270A patent/CH509806A/en not_active IP Right Cessation
- 1970-11-12 US US3728207D patent/US3728207A/en not_active Expired - Lifetime
- 1970-12-01 FR FR7043272A patent/FR2068808B1/fr not_active Expired
- 1970-12-01 BE BE759688D patent/BE759688A/en not_active IP Right Cessation
- 1970-12-08 JP JP10886970A patent/JPS4944756B1/ja active Pending
- 1970-12-10 GB GB5874470A patent/GB1333602A/en not_active Expired
- 1970-12-11 AT AT103373A patent/AT319724B/en not_active IP Right Cessation
- 1970-12-11 AT AT1117670A patent/AT313477B/en active
Also Published As
Publication number | Publication date |
---|---|
AT313477B (en) | 1974-02-25 |
JPS4944756B1 (en) | 1974-11-29 |
NL7012818A (en) | 1971-06-15 |
NL166403B (en) | 1981-03-16 |
US3728207A (en) | 1973-04-17 |
CH509806A (en) | 1971-07-15 |
DE1962331B2 (en) | 1978-03-09 |
FR2068808B1 (en) | 1973-12-07 |
BE759688A (en) | 1971-06-01 |
FR2068808A1 (en) | 1971-09-03 |
GB1333602A (en) | 1973-10-10 |
AT319724B (en) | 1975-01-10 |
NL166403C (en) | 1981-08-17 |
DE1962331A1 (en) | 1971-06-24 |
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