DE1962331C3 - Wound dressing material - Google Patents

Wound dressing material

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Publication number
DE1962331C3
DE1962331C3 DE1962331A DE1962331A DE1962331C3 DE 1962331 C3 DE1962331 C3 DE 1962331C3 DE 1962331 A DE1962331 A DE 1962331A DE 1962331 A DE1962331 A DE 1962331A DE 1962331 C3 DE1962331 C3 DE 1962331C3
Authority
DE
Germany
Prior art keywords
collagen
wound dressing
dressing material
wound
nonwoven
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1962331A
Other languages
German (de)
Other versions
DE1962331B2 (en
DE1962331A1 (en
Inventor
Wilhelm 6140 Bensheim Heling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carl Freudenberg KG
Original Assignee
Carl Freudenberg KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carl Freudenberg KG filed Critical Carl Freudenberg KG
Priority to DE1962331A priority Critical patent/DE1962331C3/en
Priority to NL7012818A priority patent/NL166403C/en
Priority to CH129371A priority patent/CH513595A/en
Priority to CH1308270A priority patent/CH509806A/en
Priority to US3728207D priority patent/US3728207A/en
Priority to BE759688D priority patent/BE759688A/en
Priority to FR7043272A priority patent/FR2068808B1/fr
Priority to JP10886970A priority patent/JPS4944756B1/ja
Priority to GB5874570A priority patent/GB1335547A/en
Priority to GB5874470A priority patent/GB1333602A/en
Priority to AT1117670A priority patent/AT313477B/en
Priority to AT103373A priority patent/AT319724B/en
Publication of DE1962331A1 publication Critical patent/DE1962331A1/en
Publication of DE1962331B2 publication Critical patent/DE1962331B2/en
Application granted granted Critical
Publication of DE1962331C3 publication Critical patent/DE1962331C3/en
Expired legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/12Layered products comprising a layer of synthetic resin next to a fibrous or filamentary layer
    • AHUMAN NECESSITIES
    • A22BUTCHERING; MEAT TREATMENT; PROCESSING POULTRY OR FISH
    • A22CPROCESSING MEAT, POULTRY, OR FISH
    • A22C13/00Sausage casings
    • A22C13/0013Chemical composition of synthetic sausage casings
    • A22C13/0016Chemical composition of synthetic sausage casings based on proteins, e.g. collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/01Non-adhesive bandages or dressings
    • A61F13/01008Non-adhesive bandages or dressings characterised by the material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325Collagen
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B1/00Layered products having a non-planar shape
    • B32B1/08Tubular products
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/30Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
    • B32B27/304Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers comprising vinyl halide (co)polymers, e.g. PVC, PVDC, PVF, PVDF
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B5/00Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
    • B32B5/02Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer
    • B32B5/022Non-woven fabric
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B5/00Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
    • B32B5/22Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed
    • B32B5/24Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed one layer being a fibrous or filamentary layer
    • B32B5/26Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed one layer being a fibrous or filamentary layer another layer next to it also being fibrous or filamentary
    • DTEXTILES; PAPER
    • D04BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04HMAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/42Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
    • D04H1/4282Addition polymers
    • D04H1/4291Olefin series
    • DTEXTILES; PAPER
    • D04BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04HMAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/42Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
    • D04H1/4326Condensation or reaction polymers
    • D04H1/4334Polyamides
    • DTEXTILES; PAPER
    • D04BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04HMAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/58Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by applying, incorporating or activating chemical or thermoplastic bonding agents, e.g. adhesives
    • D04H1/587Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by applying, incorporating or activating chemical or thermoplastic bonding agents, e.g. adhesives characterised by the bonding agents used
    • DTEXTILES; PAPER
    • D21PAPER-MAKING; PRODUCTION OF CELLULOSE
    • D21FPAPER-MAKING MACHINES; METHODS OF PRODUCING PAPER THEREON
    • D21F11/00Processes for making continuous lengths of paper, or of cardboard, or of wet web for fibre board production, on paper-making machines
    • D21F11/14Making cellulose wadding, filter or blotting paper
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00727Plasters means for wound humidity control
    • A61F2013/00731Plasters means for wound humidity control with absorbing pads
    • A61F2013/00744Plasters means for wound humidity control with absorbing pads containing non-woven
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2262/00Composition or structural features of fibres which form a fibrous or filamentary layer or are present as additives
    • B32B2262/02Synthetic macromolecular fibres
    • B32B2262/0253Polyolefin fibres
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2262/00Composition or structural features of fibres which form a fibrous or filamentary layer or are present as additives
    • B32B2262/06Vegetal fibres
    • B32B2262/062Cellulose fibres, e.g. cotton
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2305/00Condition, form or state of the layers or laminate
    • B32B2305/10Fibres of continuous length
    • B32B2305/20Fibres of continuous length in the form of a non-woven mat
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2439/00Containers; Receptacles
    • B32B2439/70Food packaging
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2597/00Tubular articles, e.g. hoses, pipes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/31504Composite [nonstructural laminate]
    • Y10T428/31855Of addition polymer from unsaturated monomers
    • Y10T428/31935Ester, halide or nitrile of addition polymer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2762Coated or impregnated natural fiber fabric [e.g., cotton, wool, silk, linen, etc.]
    • Y10T442/277Coated or impregnated cellulosic fiber fabric
    • Y10T442/2787Coating or impregnation contains a vinyl polymer or copolymer

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Textile Engineering (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Vascular Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Nonwoven Fabrics (AREA)
  • Materials For Medical Uses (AREA)
  • Laminated Bodies (AREA)

Description

Die Erfindung betrifft ein Wundauflagenmaterial aus Vliesstoff, dessen Eigenschaften gegenüber den herkömmüchen Textil-Wundverbänden wesentlich verbessert ist.The invention relates to a wound dressing material made from Non-woven fabric, the properties of which are significantly improved compared to conventional textile wound dressings is.

Es ist bekannt, Wunden mit Textilauflagen abzudekken. Derartige Auflagen werden heute fast ausschließlich verwendet. Eine einwandfreie Wundauflage muß mehrere Bedingungen erfüllen. So darf keine Reizung der Wunde eintreten, der Verband bzw. die Auflage darf nicht durch Verkrusten an der Wunde verkleben und keinen Wärmestau verursachen. Bei hoher Festigkeit ist eine ebenfalls hohe Saugfähigkeit erwünscht. Die gebräuchlichen Textil-Wundverbände und Wundauflagematerialien erfüllen diese Forderungen jedoch nur teilweise.It is known to cover wounds with textile coverings. Such requirements are almost exclusively today used. A perfect wound dressing must meet several conditions. So there must be no irritation enter the wound, the dressing or the pad must not stick to the wound with encrustation and do not cause heat build-up. With high strength, a high absorbency is also desirable. the Customary textile wound dressings and wound dressing materials only meet these requirements partially.

Der Erfindung liegt nun die Aufgabe zugrunde, ein Wundauflagematerial zu entwickeln, welches die vorstehend genannten Bedingungen vollständig erfüllt und überdies leicht zu handhaben ist.The invention is now based on the object of developing a wound dressing material which has the above mentioned conditions are fully met and, moreover, is easy to handle.

Es wird ein Wundauflagematerial vorgeschlagen, welches aus mindestens einer Vliesstoffbahn besteht und dadurch gekennzeichnet, ist, daß die Vliesstoffbahn *5 bzw. Vliesstoffbahnen mit Kollagen gebunden ist bzw. sind und die Konzentration des Kollagens über den Gesamtquerschnitt der Bahn hinweg zunimmt.A wound dressing material is proposed which consists of at least one nonwoven web and characterized in that the nonwoven web * 5 or nonwoven webs are bound with collagen and the concentration of collagen over the Total cross-section of the web away increases.

Das Binden von Faservliesen mit Kollagen ist an sich bereits bekannt. Man verwendet zu diesem Zwecke eine kollagenfasernhaltige Suspension bzw. einen Kollagcn-Faserbrci (collagen slurry). Das lose Faservlies wird mit diesem Kollagen-Faserbrei imprägniert, getrocknet und einer geeigneten Nachbehandlung unterworfen. Die so hergestellten Vlisstoffe werden z. B. als Syntheseleder verarbeitet. Entsprechende Verfahren sind in der Literatur beschrieben, z. B. in »The Journal of the American Leather Chemists Association«, Vol. LXIII, Nr. 1, Januar 1968 sowie den US-Patentschriften 3063892, 3071483, 3073714, 3233551, 3269851, < >o 32 85 775, 32 94 579. 32 94 581 und dem kanadischen Patent 7 49 911.The binding of nonwovens with collagen is already known per se. One uses a for this purpose suspension containing collagen fibers or a collagen fiber brci (collagen slurry). The loose fiber fleece is with this collagen pulp is impregnated, dried and subjected to a suitable aftertreatment. The so manufactured non-woven fabrics are z. B. processed as synthetic leather. Corresponding procedures are in the Literature described, e.g. B. in "The Journal of the American Leather Chemists Association", Vol. LXIII, No. 1, January 1968 and U.S. Patents 3063892, 3071483, 3073714, 3233551, 3269851, < > o 32 85 775, 32 94 579. 32 94 581 and the Canadian Patent 7 49 911.

Die bekannten Materialien zeichnen sich durch eine möglichst gleichförmige Verteilung von Fasern und Bindemittel (Kollagen) aus. Die Herstellungsverfahren hr> sind diesem Ziel angepaßt.The known materials are characterized by a distribution of fibers and binding agent (collagen) that is as uniform as possible. The manufacturing process hr> are adapted to this goal.

Von diesen bekannten kollagengebundenen Faservliesen unterscheidet sich das erfindungsgemäße Wundauflagematerial dadurch, daß es von einer Seite ausgehend mit Kollagen angereichert ist, wobei die Konzentration des Kollagens über den Gesamtquerschnitt der Bahn hinweg zunimmt.The wound dressing material according to the invention differs from these known collagen-bonded fiber webs in that it is enriched with collagen starting from one side, the The concentration of collagen increases over the entire cross-section of the web.

Es wurde gefunden, daß die Auflage wundfreundlicher wird, wenn der Kollagengehalt in Richtung der Wunde ansteigt. Vermutlich beruht diese Tatsache darauf, daß das Kollagen und die Wundränder einen vergleichbaren chemischen Aufbau besitzen.It has been found that the pad becomes more wound-friendly when the collagen content goes in the direction of Wound increases. Presumably this fact is due to the fact that the collagen and the wound edges are one have a comparable chemical structure.

Eine bevorzugte Ausführung des erfindungsgemäßen Wundauflagenmaterials besteht darin, daß zwei kollagengebundene Vliesstoffbahnen mit der angebenen Kollagenverteilung zusammen mit einer hochsaugfähigen Faserzwischenschicht vorgesehen sind, wobei die kollagenangereicherten Seiten der kollagengebundenen Vliesstoffbahnen außen angeordnet sind. In vielen Fällen ist es erwünscht, daß die drei Lagen punkt- oder linienförmig miteinander verschweißt sind. Hier-cj ist es erforderlich, daß wenigstens die Faserzwischenschicht ein pulverförmiges thermoplastisches Material enthält.A preferred embodiment of the wound dressing material according to the invention consists in that two collagen-bound Nonwoven webs with the specified collagen distribution together with a highly absorbent Fiber intermediate layer are provided, with the collagen-enriched sides being the collagen-bound Nonwoven webs are arranged outside. In many cases it is desirable that the three layers point or are linearly welded together. Here-cj it is required that at least the intermediate fiber layer contains a powdered thermoplastic material.

Zur Herstellung des erfindungsgemäßen Wundmaterials wird ein Fasergemisch z. B. aus gleichen Teilen Zellwolle und Zellulose in einem großen Wasserüberschuß aufgeschlämmt. Das Wasser enthält gleichzeitig den Kollagen-Faserbrei. Das Gemisch wird dann auf einem Steilsieb angeschwemmt. Auf dem Sieb sammelt sich ein Faservliesgemisch mit einem Anteil von etwa 5 bis 10 % Kollagen an, je nach der zugegebenen Menge Fasern. Am oberen Ende des Steilsicbes befindet sich ein weiterer Behälter mit einer Kollagendispersion. Diese Dispersion wird auf das darunterliegende Sieb mit dem abgelegten Vlies aufgebracht, wobei sich das Kollagen an der Oberfläche des bereits kollagenhaltigen Vlieses anreichert. Der Wasserüberschuß wird in üblicher Weise abgesaugt.To produce the wound material according to the invention, a fiber mixture is used, for. B. from equal parts Spun rayon and cellulose slurried in a large excess of water. The water contains at the same time the collagen pulp. The mixture is then washed ashore on a steep sieve. Collects on the sieve a fiber fleece mixture with a proportion of about 5 to 10% collagen, depending on the amount added Fibers. At the upper end of the steep sicbe there is another container with a collagen dispersion. This dispersion is applied to the sieve underneath with the laid fleece, whereby the Collagen accumulates on the surface of the already collagen-containing fleece. The excess water is in usually sucked off.

Das nasse Vlies wird anschließend getrocknet, indem es entweder durch eine Trockenkammer läuft oder über einen Trockenzylinder geführt wird. Hierbei tritt gleichzeitig eine Verfestigung des Materials ein.The wet fleece is then dried by either running it through a drying chamber or over it a drying cylinder is guided. At the same time, the material solidifies.

Das in dem Vlies vorhandene Kollagen kann anschließend noch gegerbt werden. Zu diesem Zweck wird das mit Kollagen verfestigte Faservlies mit einer wäßrigen. Aldehyde enthaltenden Lösung besprüht. Als Aldehyd eignet sich insbesondere Glutaraldehyd. Durch den Aldehyd wird das Kollagen gegerbt.The collagen present in the fleece can then be tanned. To this end the fiber fleece that has been consolidated with collagen is treated with an aqueous. Sprayed solution containing aldehydes. as Aldehyde is particularly suitable for glutaraldehyde. The collagen is tanned by the aldehyde.

Zur Herstellung des verschweißbaren Wundauflagematerials kann der Aufschlämmung der Textil- und Kollagenfasern in einem Überschuß von Wasser noch geringe Mengen, d.h. bis zu 10 % bezogen auf das Gewicht des Endproduktes, eines an uch bekannten thermoplastischen Pulvers, z. B. Polyvinylacetat, zugesetzt werden. Der fertige Vliesstoff kann dann in üblicher Weise, z. D. längs bestimmter Linien, thermisch verschweißt werden. Es ist so auf einfache und rationelle Weise möglich Tupfer und Saugkissen od. dgl. herzustellen. Bei Verwendung von zwei Vliesstofflagen, welche thermoplastisches Pulver enthalten, werden die Lagen so angeordnet, daß sich die kollagenarmen Flächen berühren bzw. die kollagenangereicherten Seiten nach außen zeigen.To produce the weldable wound dressing material, the slurry of the textile and collagen fibers in an excess of water can still be small amounts, ie up to 10% based on the weight of the end product, of a thermoplastic powder known from uch, e.g. B. polyvinyl acetate, may be added. The finished nonwoven fabric can then in the usual way, for. D. be thermally welded along certain lines. It is thus possible in a simple and rational way to produce swabs and absorbent pads or the like. When using two non-woven fabric layers which contain thermoplastic powder, the layers are arranged in such a way that the collagen-poor surfaces touch one another or the collagen-enriched sides point outwards.

Wie bereits erwähnt* ist es vielfach zweckmäßig, zwischen den beiden kollagenhaltigen Vliesstofflagcn noch eine weitere Lage aus hochsaugfähigen reinen Fasern anzuordnen. Das Dreischichtengebilde kann an den Rändern im Hochfrequenz- oder Wärmeimpulsverfahren verschweißt werden. Es erweicht hierbei das in den beiden äußeren Schichten vorhandene thermoplastische Pulver. Es ergibt sich ein fester Verbund allerAs already mentioned * it is often useful to place between the two collagen-containing nonwoven layers to arrange yet another layer of highly absorbent pure fibers. The three-layer structure can the edges are welded using high frequency or thermal impulse processes. It softens the in thermoplastic powders present on the two outer layers. There is a solid association of all

Schichten.Layers.

Wird ein quadratisches Dreischichtengebilde der vorstehend definierten Art an den Rändern verschweißt, so entsteht ein Wundkissen, das auf beiden Seiten wegen des hohen Kollagengehaltes dsir Außenflächen sehr wundfreundlich ist und außerdem durch die innen angeordnete hochsaugfähige Viieseinlage große Mengen an Wundsekreten aufzusaugen vermag.If a square three-layer structure of the type defined above is welded at the edges, the result is a wound pillow that has a high collagen content on both sides of the outer surface is very wound-friendly and is also large thanks to the highly absorbent Viieseinlage arranged on the inside Can absorb quantities of wound secretions.

Die Wahl der Fasern für die äußeren Schichten und auch für die innere Schicht kann weitgehend demThe choice of fibers for the outer layers and also for the inner layer can largely be the same

jeweiligen Einsatz angepaßt werden. So empfiehlt es sich häufig, bei den äußeren Schichten anstelle der üblichen Viskosefasern Synthesefasern, z, B, Polypropylenfasern, vorzusehen. Hierdurch wird eine bessere Festigkeit und eine verbesserte Durchlässigkeit des Wundsekrets zu der saugfähigen Innenschicht erzielt, weil Synthesefasern unter den angegebenen Bedingungen im Gebrauch fast nicht quellen und damit die hei der Herstellung gewählte Porosität des Materials auch :.m Gebrauch bei stark nässenden Wunden beibehalten.be adapted to the respective application. It is often advisable to use synthetic fibers, e.g. polypropylene fibers, instead of the usual viscose fibers for the outer layers. In this way, a better strength and improved permeability of the wound secretion is achieved with the absorbent inner layer, because synthetic fibers almost not swell under the conditions indicated in the use and thus the hot selected manufacture porosity of the material also: maintaining .m use with highly exuding wounds.

Claims (3)

1 Patentansprüche:1 claims: 1. Wundauflagematerial bestehend aus mindestens einer Vliesstoffbahn, dadurch gekennzeichnet, daß die Vliesstoffbahn bzw. Vliesstoffbahnen mit Kollagen gebunden ist bzw. sind und die Konzentration des Kollagens über den Gesamtquerschnitt der Bahn hinweg zunimmt1. Wound dressing material consisting of at least one nonwoven web, characterized in that that the nonwoven web or webs of nonwoven is or are bound with collagen and the The concentration of collagen increases over the entire cross-section of the web 2. Wundauflagematerial nach Anspruch 1, dadurch gekennzeichnet, daß zwei kollagengebundene Vlis-Stoffbahnen und eine hochsaugfähige Faserzwischenschicht vorgesehen sind, wobei die kollagenangereicherten Seiten der kollagengebundenen Vliesstoffbahnen außen angeordnet sind.2. Wound dressing material according to claim 1, characterized in that two collagen-bound non-woven fabric webs and a superabsorbent fiber interlayer are provided, the collagen-enriched Sides of the collagen-bonded nonwoven webs are arranged on the outside. 3. Wundauflagematerial nach Anspruch 2, dadurch '5 gekennzeichnet, daß wenigstens die Faserzwischenschicht ein pulverförmiges thermoplastisches Material enthält und die drei Lagen punkt- oder linienförmig miteinander verschweißt sind.3. wound dressing material according to claim 2, characterized in '5 that at least the fiber intermediate layer contains a powdered thermoplastic material and the point-three layers or welded linearly with each other. 2020th
DE1962331A 1969-12-12 1969-12-12 Wound dressing material Expired DE1962331C3 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE1962331A DE1962331C3 (en) 1969-12-12 1969-12-12 Wound dressing material
NL7012818A NL166403C (en) 1969-12-12 1970-08-28 WELDED CUSHION.
CH129371A CH513595A (en) 1969-12-12 1970-09-02 Nonwoven fabrics with collagen bound - fibres
CH1308270A CH509806A (en) 1969-12-12 1970-09-02 Wound dressing material
US3728207D US3728207A (en) 1969-12-12 1970-11-12 Non-woven fabric
FR7043272A FR2068808B1 (en) 1969-12-12 1970-12-01
BE759688D BE759688A (en) 1969-12-12 1970-12-01 NON WOVEN ETOFFE, ITS MANUFACTURING PROCESS AND NEW APPLICATIONS OF THIS ETOFFE
JP10886970A JPS4944756B1 (en) 1969-12-12 1970-12-08
GB5874570A GB1335547A (en) 1969-12-12 1970-12-10 Non-woven fabrics
GB5874470A GB1333602A (en) 1969-12-12 1970-12-10 Non-woven fabrics
AT1117670A AT313477B (en) 1969-12-12 1970-12-11 Collagen-containing wound dressing
AT103373A AT319724B (en) 1969-12-12 1970-12-11 Sausage casing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1962331A DE1962331C3 (en) 1969-12-12 1969-12-12 Wound dressing material

Publications (3)

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DE1962331A1 DE1962331A1 (en) 1971-06-24
DE1962331B2 DE1962331B2 (en) 1978-03-09
DE1962331C3 true DE1962331C3 (en) 1978-11-02

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DE1962331A Expired DE1962331C3 (en) 1969-12-12 1969-12-12 Wound dressing material

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US (1) US3728207A (en)
JP (1) JPS4944756B1 (en)
AT (2) AT319724B (en)
BE (1) BE759688A (en)
CH (1) CH509806A (en)
DE (1) DE1962331C3 (en)
FR (1) FR2068808B1 (en)
GB (1) GB1333602A (en)
NL (1) NL166403C (en)

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ZA774782B (en) * 1976-08-19 1979-03-28 Colgate Palmolive Co Absorbent article
AT356285B (en) * 1977-06-30 1980-04-25 Bunzl & Biach Ag FABRIC
DE3124028A1 (en) * 1981-06-19 1982-12-30 Naturin-Werk Becker & Co, 6940 Weinheim DOUBLE-LAYERED SAUSAGE CASE MADE FROM AN OUTER TEXTILE FABRIC AND AN INTERNAL COLLAGEN COATING AND METHOD FOR THE PRODUCTION THEREOF AND THE USE OF THIS SAUSAGE CASE OF RAW AND BREAD SAUSAGE
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US6017359A (en) 1993-05-25 2000-01-25 Vascular Solutions, Inc. Vascular sealing apparatus
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CN104007040B (en) * 2014-06-05 2016-05-18 广州纺织服装研究院有限公司 A kind of method that detects collagen content in cover type collagen modification fabric
CN106309150B (en) * 2015-06-29 2020-10-30 烟台蓝创生物技术有限公司 Medical collagen dressing and preparation method and application thereof
ES2842501T5 (en) 2015-09-21 2023-04-13 Modern Meadow Inc Fiber Reinforced Fabric Composite Materials
US11542374B2 (en) 2016-02-15 2023-01-03 Modern Meadow, Inc. Composite biofabricated material
US20190024303A1 (en) * 2017-07-18 2019-01-24 Modern Meadow, Inc. Biofabricated leather articles, and methods thereof
AU2018253595A1 (en) 2017-11-13 2019-05-30 Modern Meadow, Inc. Biofabricated leather articles having zonal properties
CN113286864A (en) 2019-01-17 2021-08-20 现代牧场股份有限公司 Layered collagen material and preparation method thereof

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IL23096A (en) * 1964-03-31 1968-11-27 Usm Corp Manufacture of strong fibrous material
FR1500852A (en) * 1964-09-10 1968-01-24
US3523536A (en) * 1966-02-26 1970-08-11 Johnson & Johnson Absorbent fibrous products
DE1635500A1 (en) * 1967-12-27 1972-05-18 Freudenberg Carl Process for the production of synthetic shoe upper leather

Also Published As

Publication number Publication date
AT313477B (en) 1974-02-25
JPS4944756B1 (en) 1974-11-29
NL7012818A (en) 1971-06-15
NL166403B (en) 1981-03-16
US3728207A (en) 1973-04-17
CH509806A (en) 1971-07-15
DE1962331B2 (en) 1978-03-09
FR2068808B1 (en) 1973-12-07
BE759688A (en) 1971-06-01
FR2068808A1 (en) 1971-09-03
GB1333602A (en) 1973-10-10
AT319724B (en) 1975-01-10
NL166403C (en) 1981-08-17
DE1962331A1 (en) 1971-06-24

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