CN2897151Y - Heart connecting conduct operation station - Google Patents

Heart connecting conduct operation station Download PDF

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Publication number
CN2897151Y
CN2897151Y CNU2006200400819U CN200620040081U CN2897151Y CN 2897151 Y CN2897151 Y CN 2897151Y CN U2006200400819 U CNU2006200400819 U CN U2006200400819U CN 200620040081 U CN200620040081 U CN 200620040081U CN 2897151 Y CN2897151 Y CN 2897151Y
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China
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signal
circuit
main controller
acquisition module
amplifier
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Expired - Fee Related
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CNU2006200400819U
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Chinese (zh)
Inventor
陈广元
夏振宏
李强
纵建羽
刘文敬
李建超
薛诚
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LAIEN BIOMEDICAL TECH CO LTD SHANGHAI
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LAIEN BIOMEDICAL TECH CO LTD SHANGHAI
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Priority to CNU2006200400819U priority Critical patent/CN2897151Y/en
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Publication of CN2897151Y publication Critical patent/CN2897151Y/en
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Abstract

The utility model relates to a heart catheter operation station, comprising a main controller, an amplifier signal acquisition unit, an A/D acquisition module, a multi-channel built-in process stimulation instrument, a display unit, a laser printer and an isolation power source module etc seven modules; The body signal acquisitioned by the amplifier signal acquisition unit is sent to the A/D acquisition module and accesses to the main controller after analog-digital conversion; The multi-channel built-in process stimulation instrument is connected to the series interface of the main controller, and then connected to the parallel interface of the main controller; A multi-screen driver is arranged in the main controller connected with the display unit; The laser printer is connected to the parallel interface of the main controller; The isolation power source module is connected to the amplifier signal acquisition unit, the main controller, the display unit and the laser printer. The utility model has the advantages of collection, amplifying, recording and analyzing the standard 12 lead body surface cardiograph signal, 16-64 channel cardiocoelomic cardiograph signal, 2-6 channel invasive blood pressure signal and 2-4 channel cardiac muscle cell single phase action potential level signal, and outputting multi-channel endocardiac stimulation pulse.

Description

The cardiac catheter work station
Technical field
This utility model relates to a kind of clinical treatment instrument, relate in particular to a kind ofly can gather, amplify, electrocardio (IECG) signal, 2-6 passage invasive blood pressure (IBP) signal and 2-4 passage myocardial cell monophasic action potential (MAP) signal in record and analytical standard 12 lead body surface electrocardiogram (ECG) signal, the 16-64 passage chambers of the heart, and the cardiac catheter work station of the intracardiac boost pulse of exportable multichannel.
Background technology
The cardiac catheter work station is one of indispensable equipment in the cardiovascular disease invasive diagnosis treatment operation.It is a kind of comprehensive monitoring, diagnosing instrument, by the various physiology signals of acquisition and recording, and after it is carried out digitized processing, by computer it is analyzed and handles, for clinical usefulness the diagnosis of cardiovascular disease such as coronary heart disease, arrhythmia, congenital heart disease and intervention property inspection treatment.But all there is following some deficiency in the heart intervention treating equipment of making a general survey of on the domestic market:
1, outside extended capability is not strong, and uncontrollable external radio frequency energy output equipment also can't obtain and write down the relevant parameter of radio-frequency (RF) energy, and the analysis of adversary's postoperative has brought great inconvenience.
2, do not possess the built-in programmable stimulator of multichannel, in clinical operation, need finish stimulatory function by extra equipment.Cause synchronous recording physiological signal, stimulus signal and relevant stimulus parameter in real time.
3, owing to the particularity of MAP amplifier, gathered the MAP signal in the past and all adopted external MAP preamplifier, and used battery powered, made that the motility of obtaining the MAP signal was very low.
The utility model content
At the above-mentioned deficiency of prior art, technical problem to be solved in the utility model is to propose the cardiovascular disease diagnosis of the intracardiac stimulation output of a kind of ECG of having, IECG, IBP, MAP and multichannel and the cardiac catheter work station of research.
For solving the problems of the technologies described above, the cardiac catheter work station that the utility model proposes adopts seven big module combinations to form, they are respectively: main controller, amplifier signal collecting unit, A/D acquisition module, the built-in programmable stimulator of multichannel, display unit, laser printer and insulating power supply module, wherein, the human body signal of amplifier signal collecting unit collection is sent into the A/D acquisition module, carries out inserting main controller after the analog digital conversion; The serial port of built-in programmable stimulator of multichannel and main controller is connected the back and inserts the amplifier signal collecting unit; Main controller is built-in with the multi-screen driver and connects display unit; The parallel port of laser printer and main controller is connected; The insulating power supply module is connected with amplifier signal collecting unit, main controller, display unit and laser printer.
Above-mentioned amplifier signal collecting unit comprises four unit: lead standard body surface electrocardiogram acquisition module, invasive blood pressure signal acquisition module and myocardial cell monophasic action potential signal acquisition module of ecg signal acquiring module, 12 in the chambers of the heart.Described chambers of the heart heart signal module is to gather electrocardiosignal in the chambers of the heart, and signal is from the input of electrocardio conduit, delivers to the A/D acquisition module after low-pass filtering and impedance matching adjustment, amplification, isolation, finishes the collection and the digitized of signal; The described 12 standard body surface electrocardiogram acquisition modules of leading are to gather the body surface electrocardiosignal, be connected picked up signal by external electrode with human body, after low-pass filtering and common mode inhibition adjustment, enter amplifying circuit, output to the A/D acquisition module by isolated amplifier at last, carry out the digitized of signal; Described invasive blood pressure signal acquisition module is to gather the invasive blood pressure signal of the abiotic signal of telecommunication, convert non-electrical signal to the signal of telecommunication by strain pressure transducer, after amplifying by bridge circuit again, output to A/D by isolated amplifier and gather port, carry out signal digitalized; Described myocardial cell monophasic action potential signal acquisition module is the acquisition process to the MAP signal, human body signal is connected to elementary low-pass filter circuit through the MAP leading electrode, again after impedance matching is adjusted, enter secondary filter circuit, then through the elementary third level filter circuit that is amplified into, three grades of filtered signals carry out the secondary difference again and amplify, and after isolated amplifier and final stage filter circuit output to the A/D acquisition module, carry out signal digitalized.
The built-in programmable stimulator of above-mentioned multichannel is controlled by serial port by main controller, can provide the stimulation channels title for the microprocessor that stimulates instrument itself, stimulate parameters such as kind, stimulation voltage, stimulation pulsewidth and time delay.Embedded microprocessor cooperates the perception of R ripple to export corresponding boost pulse from the I/O port one according to relevant parameter in the built-in programmable stimulator of multichannel, send into the stimulation power amplifying circuit then, amplify and boost, select corresponding relays output boost pulse by multiplexer circuit again.
With respect to prior art, this utility model combines modern microcomputer technology, embedding microprocessor technology, modern large scale integrated circuit, modern signal processing technology.By real-time demonstration, analysis, record, storage physiological signal, control in real time stimulates multinomial functions such as output channel and stimulus type, makes invasive diagnosis treatments such as electrophysiologic study art and catheter ablation art and coronary heart disease, arrhythmia, congenital heart disease convenient, safe, reliable.Electrocardiosignal, invasive blood pressure signal, myocardial cell monophasic action potential signal in standard human body surface electrocardiogram signal, the chambers of the heart can be gathered, handle, analyze, show, store and be printed to this utility model, realized the digitized of human body associated electrical signals, and can provide multiple programmed electrical stimulation pulse by multichannel and bring out and duplicate arrhythmia.In addition, in order to guarantee patient's safety to greatest extent, amplifying circuit that this utility model is all and associated control signal all adopt the circuit form of floating, it can effectively solve the real-time multichannel programmed electrical stimulation of the shortage function of heart intervention treating equipment existence such as existing polygraph, problems such as the flexibility ratio of uncontrollable external radio frequency energy output equipment and acquisition MAP signal is low make that interventional therapies operations such as clinical electric physiology inspection and catheter ablation art are more simple and convenient.
Description of drawings
Fig. 1 is this utility model machine system structure chart.
Fig. 2 is this utility model myocardial cell individual event action potential signal acquisition module theory diagram.
Fig. 3 is the built-in programmable stimulator schematic diagram of this utility model multichannel.
Fig. 4 is the stimulation power amplifying circuit schematic diagram of the built-in programmable stimulator of this utility model multichannel.
Fig. 5 is that the warning circuit schematic diagram is provided in the stimulation of the built-in programmable stimulator of this utility model multichannel.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is described in further detail.
As shown in Figure 1, the cardiac catheter work station that this utility model one preferred embodiment provides, it comprises main controller, amplifier signal collecting unit, A/D acquisition module, the built-in programmable stimulator of multichannel, display unit, laser printer and insulating power supply module seven big modules, wherein: the human body signal of amplifier signal collecting unit collection is sent into the A/D acquisition module, carries out inserting main controller after the analog digital conversion; The serial port of built-in programmable stimulator of multichannel and main controller is connected the back and inserts the amplifier signal collecting unit; Main controller is built-in with the multi-screen driver and connects display unit; The parallel port of laser printer and main controller is connected; The insulating power supply module is connected with amplifier signal collecting unit, main controller, display unit and laser printer.
Wherein, it is hardware platform that the main controller unit adopts high performance commercial PC, and application architecture is under Windows2000 operating system.Display unit utilizes the double screen Display Technique, and two display are divided into control display screen curtain and real-time display screen.Main controller is built-in with the multi-screen driver, can extend out display screen arbitrarily thus.Main controller is connected by the built-in programmable stimulator of serial port and multichannel, controls passage that stimulates output and the type that stimulates output with this; The parallel port of laser printer and main controller is connected, and the data that institute is gathered and stores print output; External radio-frequency (RF) energy outut device is controlled by another serial port by main controller, and with the power curve and the temperature curve of radio frequency outut device, in the real-time specific region that is presented on the control screen.The insulating power supply module is that it is separated each module and mains system by isolation technology for amplifier signal collecting unit, main controller, display unit, laser printer provide power supply, has improved the safety of whole instrument.In addition, all amplifying circuit and associated control signals all adopt the circuit form of floating.
As shown in Figure 1, the amplifier signal collecting unit is made up of lead standard body surface electrocardiogram acquisition module, invasive blood pressure signal acquisition module and myocardial cell monophasic action potential signal acquisition module of ecg signal acquiring module, 12 in the chambers of the heart.Each acquisition module is relatively independent, mainly is to finish electricity physiological signal and non-electricity physiological signal collection and processing.Chambers of the heart heart signal module is to gather electrocardiosignal in the chambers of the heart, and signal is from the input of electrocardio conduit, delivers to the A/D acquisition module after low-pass filtering and impedance matching adjustment, amplification, isolation, carries out the digitized of signal; The 12 standard body surface electrocardiogram acquisition modules of leading are to gather the body surface electrocardiosignal, be connected with human body and obtain the body surface signal by the standard body surface line that leads, after low-pass filtering and common mode inhibition adjustment, enter amplifying circuit, output to the A/D acquisition module by isolated amplifier at last, carry out the digitized of signal; The invasive blood pressure signal acquisition module is to gather the invasive blood pressure signal of the abiotic signal of telecommunication, insert in the human heart by conduit, convert the signal of telecommunication to by strain pressure transducer, constant-current source in the amplifier is connected with the power supply of pick off, for pick off provides the energy, signal outputs to the A/D acquisition module by isolated amplifier after amplifying by bridge circuit.
Be myocardial cell monophasic action potential (MAP) signal acquisition module schematic diagram as shown in Figure 2, it mainly finishes the acquisition process of MAP signal.Human body signal is connected with elementary filter circuit and holding circuit by the MAP leading electrode, and elementary filtered electrical routing resistance and electric capacity are formed; Holding circuit is the bridge rectifier that four diodes are formed, and plays the effect of anti-defibrillation.Enter the impedance matching circuit of being made up of two AD822AR chips through elementary filtered signal, after the impedance conversion, signal enters the secondary filter circuit of being made up of resistance and electric capacity and carries out filtering.Enter the elementary differential amplifier circuit of being made up of chip I NA128U through secondary filtered signal and carry out the signal amplification, the signal after the amplification enters the third level filter circuit of being made up of resistance and electric capacity, further filtering noise; Signal enters second level differential amplifier circuit again and carries out signal and amplify subsequently, and second level differential amplifier circuit is made up of chip I NA128U.Signal after secondary amplifies enters the buffer circuit of being made up of chip I SO124P again, outputs to the A/D acquisition module after the third level low-pass filtering via resistance and electric capacity composition at last, carries out signal digitalized.Level circuit supply before and after independently prime insulating power supply and back level insulating power supply are respectively is to improve the safety of instrument.
Be illustrated in figure 3 as the built-in programmable stimulator theory diagram of multichannel.Main controller transmits order by the communication interface circuit of built-in programmable stimulator, and control stimulates the kind of output channel and stimulation.Be connected with the PORT COM of embedded microprocessor by two-way buffer circuit with the communication interface circuit that driving chip MAX202 forms by electric capacity.Two-way buffer circuit is made up of chip I SO150.After microprocessor is upset order, export corresponding boost pulse to the stimulation power amplifying circuit from the I/O port one.The principle of stimulation power amplifying circuit as shown in Figure 4.Signal by the output of stimulation power amplifying circuit enters the holding circuit of being made up of resistance and audion again, sends into corresponding stimulation channels output at last.Boost pulse enters to stimulate simultaneously provides warning circuit (as shown in Figure 5), and it is made of four NAND gate and a buzzer, reminds the user boost pulse to begin to provide synchronously, and alerting pattern mainly is to pass through sound.The embedding I/O port of handling 2 that declines is connected with MUX 74HC138, according to ordering the passage of selecting to stimulate output.The output of " emergency pacing " key enters the twitter circuit of being made up of chip MAX6816 that disappears, and the middle fracture of the output of the twitter circuit that disappears and microprocessor is connected.
Be illustrated in figure 4 as the stimulation power amplifying circuit schematic diagram in the built-in programmable stimulator module of multichannel.INC (cursor slide moves control signal) is connected with digital regulation resistance U1 respectively with U/D (potentiometer resistance lifting/lowering control signal), is used to control the size that stimulates output.Enter again by resistance and amplifier U2 through the signal of digital regulation resistance U1 output and tentatively to amplify, carry out two triodes subsequently and carry out secondary and amplify, export holding circuit at last to.

Claims (8)

1, a kind of cardiac catheter work station, it is characterized in that, it comprises main controller, amplifier signal collecting unit, A/D acquisition module, the built-in programmable stimulator of multichannel, display unit, laser printer and insulating power supply module seven big modules, wherein: the human body signal of amplifier signal collecting unit collection is sent into the A/D acquisition module, carries out inserting main controller after the analog digital conversion; The serial port of built-in programmable stimulator of multichannel and main controller is connected the back and inserts the amplifier signal collecting unit; Main controller is built-in with the multi-screen driver and connects display unit; The parallel port of laser printer and main controller is connected; The insulating power supply module is connected with amplifier signal collecting unit, main controller, display unit and laser printer.
2, cardiac catheter work station according to claim 1, it is characterized in that the amplifier signal collecting unit comprises four unit: lead standard body surface electrocardiogram acquisition module, invasive blood pressure signal acquisition module and myocardial cell monophasic action potential signal acquisition module of ecg signal acquiring module, 12 in the chambers of the heart.
3, cardiac catheter work station according to claim 2, it is characterized in that the human body signal of chambers of the heart heart signal module to obtaining from the input of electrocardio conduit is after low-pass filtering and impedance matching adjustment, amplify, deliver to the A/D acquisition module after the isolation and carry out analog digital conversion.
4, cardiac catheter work station according to claim 2, it is characterized in that, the 12 standard body surface electrocardiogram acquisition modules of leading are connected picked up signal by the standard body surface line that leads with human body, after low-pass filtering and common mode inhibition adjustment, enter amplifying circuit, output to the A/D acquisition module by isolated amplifier at last, carry out the digitized of signal.
5, cardiac catheter work station according to claim 2, it is characterized in that, the invasive blood pressure signal acquisition module is by strain pressure transducer the invasive blood pressure conversion of signals of non-electrical signal to be become the signal of telecommunication, constant-current source in the amplifier is connected with the power supply of pick off, after signal amplifies by bridge circuit, output to the A/D acquisition module by isolated amplifier and carry out analog digital conversion.
6, cardiac catheter work station according to claim 2, it is characterized in that, myocardial cell monophasic action potential signal acquisition module utilizes the MAP leading electrode that human body signal is inputed to elementary filter circuit and holding circuit, and elementary filtered electrical routing resistance and electric capacity are formed; The bridge rectifier that holding circuit is made up of four diodes; Enter the impedance matching circuit of being made up of two AD822AR chips through elementary filtered signal, after the impedance conversion, signal enters the secondary filter circuit of being made up of resistance and electric capacity and carries out filtering; Enter the elementary differential amplifier circuit of being made up of chip I NAl28U through secondary filtered signal and carry out the signal amplification, the signal after the amplification enters the third level filter circuit of being made up of resistance and electric capacity; Further behind the filtering noise, enter second level differential amplifier circuit again and carry out the signal amplification, second level differential amplifier circuit is made up of chip I NAl28U; Signal after secondary amplifies enters the buffer circuit of being made up of chip I SO124P again, outputs to the A/D acquisition module after the third level low-pass filtering via resistance and electric capacity composition at last, carries out digital-to-analogue conversion; Level circuit supply before and after independently prime insulating power supply and back level insulating power supply are respectively.
7, cardiac catheter work station according to claim 1 is characterized in that, the built-in programmable stimulator of multichannel transmits order by main controller, controls the kind that it stimulates output channel and stimulation; Be connected with the PORT COM of embedded microprocessor by two-way buffer circuit with the communication interface circuit that driving chip MAX202 forms by electric capacity; Two-way buffer circuit is made up of chip I SO150; After microprocessor is upset order, export corresponding boost pulse from the I/O port one, the stimulation power amplifying circuit through being made up of digital regulation resistance U1, resistance and amplifier U2 carries out power amplification; INC is connected with digital regulation resistance U1 respectively with U/D; Signal by the output of stimulation power amplifying circuit enters the holding circuit of being made up of resistance and audion again, sends into corresponding stimulation channels output at last; Boost pulse enters to stimulate simultaneously provides warning circuit, reminds the user boost pulse to begin to provide synchronously, and alerting pattern mainly is by sound, and it is made of four NAND gate and a buzzer; The embedding I/O port of handling 2 that declines is connected with MUX 74HC138, according to ordering the passage of selecting to stimulate output; The output of " emergency pacing " key enters the twitter circuit of being made up of chip MAX6816 that disappears, and the middle fracture of the output of the twitter circuit that disappears and microprocessor is connected.
8, cardiac catheter work station according to claim 1 is characterized in that, another serial port of external radio-frequency (RF) ablation energy output equipment and main controller is connected.
CNU2006200400819U 2006-03-10 2006-03-10 Heart connecting conduct operation station Expired - Fee Related CN2897151Y (en)

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102525641A (en) * 2010-10-28 2012-07-04 韦伯斯特生物官能(以色列)有限公司 Routing of pacing signals
CN103028192A (en) * 2011-07-26 2013-04-10 通用电气公司 System and method of electrical current detection in electrophysiology study
CN103584911A (en) * 2013-08-21 2014-02-19 上海慧达医疗器械有限公司 Electrical stimulation and ablation instrument for renal sympathetic nerves
CN103648375A (en) * 2011-04-12 2014-03-19 麦德托尼克消融前沿有限公司 Electrophysiological signal processing and utilization
CN104337510A (en) * 2013-08-02 2015-02-11 深圳华腾生物医疗电子有限公司 Technical solution for integration of conventional cardiogram monitor and temporary cardiac pacing function
CN104856667A (en) * 2014-02-25 2015-08-26 深圳华腾生物医疗电子有限公司 Novel non-invasion arrhythmia diagnosis and treatment technology and multi-parameter monitor integrated product
CN104981217A (en) * 2013-06-27 2015-10-14 日本来富恩株式会社 Catheter system
CN109364374A (en) * 2013-12-19 2019-02-22 拜克比特医疗公司 For controlling the method and system of blood pressure by control atrial pressure
US11389658B2 (en) 2015-09-11 2022-07-19 Backbeat Medical, Llc Methods and systems for treating cardiac malfunction
US11406829B2 (en) 2004-02-12 2022-08-09 Backbeat Medical, Llc Cardiac stimulation apparatus and method for the control of hypertension
US11426589B2 (en) 2016-04-22 2022-08-30 Backbeat Medical, Llc Methods and systems for controlling blood pressure
US11452875B2 (en) 2012-12-21 2022-09-27 Backbeat Medical, Llc Methods and systems for lowering blood pressure through reduction of ventricle filling
US11529520B2 (en) 2006-09-25 2022-12-20 Backbeat Medical, Llc Methods and apparatus to stimulate heart atria
US11577059B2 (en) 2005-03-02 2023-02-14 Backbeat Medical, Llc Methods and apparatus to increase secretion of endogenous naturetic hormones
US11759639B2 (en) 2008-09-08 2023-09-19 Backbeat Medical, Llc Methods and apparatus to stimulate the heart

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11406829B2 (en) 2004-02-12 2022-08-09 Backbeat Medical, Llc Cardiac stimulation apparatus and method for the control of hypertension
US11577059B2 (en) 2005-03-02 2023-02-14 Backbeat Medical, Llc Methods and apparatus to increase secretion of endogenous naturetic hormones
US11529520B2 (en) 2006-09-25 2022-12-20 Backbeat Medical, Llc Methods and apparatus to stimulate heart atria
US11759639B2 (en) 2008-09-08 2023-09-19 Backbeat Medical, Llc Methods and apparatus to stimulate the heart
CN102525641A (en) * 2010-10-28 2012-07-04 韦伯斯特生物官能(以色列)有限公司 Routing of pacing signals
CN102525641B (en) * 2010-10-28 2016-02-17 韦伯斯特生物官能(以色列)有限公司 The Route Selection of pacing signal
US10039502B2 (en) 2011-04-12 2018-08-07 Medtronic Ablation Frontiers Llc Electrophysiological signal processing and utilization
CN103648375A (en) * 2011-04-12 2014-03-19 麦德托尼克消融前沿有限公司 Electrophysiological signal processing and utilization
CN103648375B (en) * 2011-04-12 2016-11-16 麦德托尼克消融前沿有限公司 Electrophysiology signals processes and utilizes
CN103028192A (en) * 2011-07-26 2013-04-10 通用电气公司 System and method of electrical current detection in electrophysiology study
CN103028192B (en) * 2011-07-26 2016-02-24 通用电气公司 The system and method for current detecting in electrophysiologic studies
US11452875B2 (en) 2012-12-21 2022-09-27 Backbeat Medical, Llc Methods and systems for lowering blood pressure through reduction of ventricle filling
US11712567B2 (en) 2012-12-21 2023-08-01 Backbeat Medical, Llc Methods and systems for controlling blood pressure by controlling atrial pressure
US11986661B2 (en) 2012-12-21 2024-05-21 Backbeat Medical, Llc Methods and systems for lowering blood pressure through reduction of ventricle filling
CN104981217A (en) * 2013-06-27 2015-10-14 日本来富恩株式会社 Catheter system
CN104981217B (en) * 2013-06-27 2017-10-13 日本来富恩株式会社 Conduit system
CN104337510A (en) * 2013-08-02 2015-02-11 深圳华腾生物医疗电子有限公司 Technical solution for integration of conventional cardiogram monitor and temporary cardiac pacing function
CN103584911B (en) * 2013-08-21 2015-12-02 上海慧达医疗器械有限公司 A kind of renal sympathetic nerve electricity irritation ablatograph
CN103584911A (en) * 2013-08-21 2014-02-19 上海慧达医疗器械有限公司 Electrical stimulation and ablation instrument for renal sympathetic nerves
CN109364374B (en) * 2013-12-19 2022-08-12 拜克比特医疗有限责任公司 Method and system for controlling blood pressure by controlling atrial pressure
CN109364374A (en) * 2013-12-19 2019-02-22 拜克比特医疗公司 For controlling the method and system of blood pressure by control atrial pressure
CN104856667A (en) * 2014-02-25 2015-08-26 深圳华腾生物医疗电子有限公司 Novel non-invasion arrhythmia diagnosis and treatment technology and multi-parameter monitor integrated product
US11389658B2 (en) 2015-09-11 2022-07-19 Backbeat Medical, Llc Methods and systems for treating cardiac malfunction
US11426589B2 (en) 2016-04-22 2022-08-30 Backbeat Medical, Llc Methods and systems for controlling blood pressure
US11969598B2 (en) 2016-04-22 2024-04-30 Backbeat Medical, Llc Methods and systems for controlling blood pressure

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Granted publication date: 20070509

Termination date: 20130310