CN220154448U - Totally enclosed type device for collecting and rapidly detecting samples - Google Patents

Totally enclosed type device for collecting and rapidly detecting samples Download PDF

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Publication number
CN220154448U
CN220154448U CN202320890351.9U CN202320890351U CN220154448U CN 220154448 U CN220154448 U CN 220154448U CN 202320890351 U CN202320890351 U CN 202320890351U CN 220154448 U CN220154448 U CN 220154448U
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China
Prior art keywords
sampling tube
collecting
fixing
totally enclosed
utility
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CN202320890351.9U
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Chinese (zh)
Inventor
朱绍荣
杨宇
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SHANGHAI RONGSHENG BIOLOGICAL PHARMACEUTICAL CO Ltd
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SHANGHAI RONGSHENG BIOLOGICAL PHARMACEUTICAL CO Ltd
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Abstract

The utility model provides a totally enclosed device for collecting and rapidly detecting samples, which comprises: the device comprises a sampling tube, a shell, a detection plate and a base; one side of the shell is connected with the sampling tube, the other side of the shell is connected with the detection plate, and the bottom of the shell is connected with the base. The utility model combines the sampling step and the detection step into one device, has simple operation, rapid detection and high practicality and patient compliance.

Description

Totally enclosed type device for collecting and rapidly detecting samples
Technical Field
The utility model belongs to the field of detection, and in particular relates to a totally-enclosed type sample collecting and rapid detecting device.
Background
The detection device is used for containing chemical reagents for detecting chemical components, drug residues, virus types and the like, and is used by general hospitals and pharmaceutical enterprises. At present, when detecting the sample, generally need the manual work to use independent instrument to take a sample to the reagent, the rethread manual work detects in the device of detecting the sample, because sample step and detection step need separate, go on alone, lead to complex operation, use inconvenient, detect for a long time, practicality and patient compliance are lower.
Thus, there is a need for a device for collecting and rapidly detecting samples.
Disclosure of Invention
The utility model aims to provide a totally-enclosed sample collecting and rapid detecting device, which combines a sampling step and a detecting step into one device, and has the advantages of simple operation, rapid detection and high practicality and patient compliance.
In a first aspect of the present utility model, there is provided a totally enclosed device for collecting and rapidly detecting samples, the device comprising: the device comprises a sampling tube, a shell, a detection plate and a base; one side of the shell is connected with the sampling tube, the other side of the shell is connected with the detection plate, and the bottom of the shell is connected with the base;
the sampling tube includes: the device comprises a sampling tube cover, a sampling tube body, a sampler connected to the sampling tube cover and fixing sheets connected to two sides of the bottom of the sampling tube body, wherein the sampling tube body is used for containing a pyrolysis liquid for splitting a sample into a tested object;
the detection plate is used for fixing a reagent which specifically binds with a sample;
the base includes: the liquid storage pool is used for containing liquid, a groove is fixed on the base, and a thimble is positioned in the middle of the groove and can puncture the bottom of the sampling tube, wherein the groove is provided with two pairs of depressions, one pair of depressions is lower than the thimble, and the other pair of depressions is higher than the thimble; the fixing piece on the sampling tube can be placed in any pair of recesses of the groove.
In one or more aspects of the present utility model, the sampling tube cap and the sampling tube body are detachably connected together.
In one or more aspects of the utility model, the inner side of the sampling tube cap has complementary threads that fully engage the top of the sampling tube body.
In one or more aspects of the utility model, the sampler has a suction assembly and a sampling straw, the suction assembly being connected to a sampling tube cover by the sampling straw.
In one or more aspects of the present utility model, the detection plate includes: the display frame is detachably connected with the detection card.
In one or more modes of the utility model, a plurality of fixing columns are arranged on the display frame, a plurality of fixing rings are arranged on the detection card, and the fixing columns and the fixing rings are detachably connected together in a bolt mode.
In one or more aspects of the utility model, the number of the fixing posts and the fixing rings is uniform and arranged in pairs.
In one or more aspects of the utility model, the housing is removably coupled to the sampling tube, the sensing plate, and the base.
In one or more aspects of the present utility model, the base further includes: a fixed sheet and a limiting sheet for fixing the detection plate.
In one or more modes of the utility model, the thimble is cross-shaped, and the groove is annular.
In one or more aspects of the utility model, the test card also contains the reagents necessary to perform the appropriate test to generate the detectable signal.
In one or more aspects of the utility model, the test card is a test card for a gastric disease that is a helicobacter pylori infection disease of the stomach.
In one or more aspects of the utility model, the sample comprises oral fluid, saliva, blood, serum, plasma, urine, stool, spinal fluid, vaginal extract, mucus, tissue fluid.
In one or more aspects of the utility model, the test substance includes a drug, a hormone, a protein, a polypeptide, a nucleic acid molecule, a pathogen, and a specific binding substance.
Other aspects of the utility model will be apparent to those skilled in the art in view of the disclosure herein.
Drawings
Fig. 1 is a perspective front view of the detection device of the present utility model.
Fig. 2 is a front view of the detection device of the present utility model after the detection device is disassembled.
Fig. 3 is a perspective view of the detection device of the present utility model after the detection device is disassembled.
Fig. 4 is a bottom view of the detection device of the present utility model after the detection device is disassembled.
Fig. 5 is a front view showing the internal structure of the detection device of the present utility model.
FIG. 6 is a front view showing the internal structure of the detecting unit according to the present utility model when the sampling tube is in an open state.
FIG. 7 is a plan view showing the internal structure of the detecting unit according to the present utility model when the sampling tube is in a closed state and rotated to the position of the locking groove.
Wherein, each reference sign corresponds as follows:
1. a sampling tube;
101. a sampling tube cover;
102. a sampling tube body;
103. a sampler;
104. a fixing piece;
105. a water absorbing component;
106. a sampling pipette;
2. a housing;
3. a detection plate;
301. a display frame;
302. a detection card;
303. a fixing ring;
304. fixing the column;
4. a base;
401. a liquid storage tank;
402. a groove;
403. a fixing piece;
404. a limiting piece;
405. and (5) a thimble.
Detailed Description
The present utility model relates to a device for collecting a sample and detecting the presence or absence of an analyte or a physical property of the sample.
In describing embodiments of the present utility model in detail, the schematic drawings showing the structure of the device are not to scale in detail and are merely illustrative and should not be taken as limiting the scope of the present utility model. In addition, the three-dimensional dimensions of length, width and depth should be included in actual fabrication.
As the context clearly indicates otherwise, the terms "comprises" and "comprising" generally only indicate that the steps and elements specifically identified are included, but that the method or apparatus does not constitute an exclusive list, but rather that the method or apparatus may include other steps or elements.
The device of the utility model
The present utility model provides a device for collecting a sample while detecting the presence or absence of an analyte or a physical property of the sample, the device comprising: sampling tube, shell, pick-up plate and base. One side of the shell is connected with the sampling tube, the other side of the shell is connected with the detection plate, and the bottom of the shell is connected with the base.
In a preferred form of the utility model, the housing is integrally formed with a space for receiving the sampling tube on one side and a space for receiving the sensing plate on the other side.
In a preferred form of the utility model, the housing is removably coupled to the sampling tube, the sensing plate and the base.
In a preferred mode of the present utility model, the sampling tube includes: the sampling tube cover, the sampling tube body, connect the sampler on the sampling tube cover to and connect the stationary blade in sampling tube body bottom both sides.
In a preferred form of the utility model, the sampling tube cap and the sampling tube body are removably connected together.
In a preferred form of the utility model, the inner side of the sampling tube cap has complementary threads that fully engage the top of the sampling tube body.
In a preferred embodiment of the utility model, the sampler is fixedly connected to the sampling tube cap.
In a preferred mode of the utility model, the fixing piece is fixedly connected with the bottom of the sampling tube body.
In a preferred form of the utility model, the sampling tube cap is rotatably and detachably connected to the sampling tube body.
In a preferred form of the utility model, the sampler has a suction assembly and a sampling straw.
In a preferred form of the utility model, the absorbent assembly may be a sponge, foam or any material suitable for absorbing liquids.
In a preferred form of the utility model, the water absorbing assembly is connected to the sampling tube cap by a sampling pipette.
In a preferred form of the utility model, the sampling pipette is used to receive and collect a sample taken.
The sample may be any liquid sample including oral fluid, saliva, blood, serum, plasma, urine, stool, spinal fluid, vaginal extract, mucus, interstitial fluid.
In a preferred mode of the present utility model, the sample tube body may be filled with a lysis solution for lysing the sample into the analyte. When the sampling is finished, the sampler is put back to the sampling tube body, and the sample can interact with the pyrolysis liquid in the sampling tube body to crack out the object to be detected.
The test substance may be any substance that is known or developed to be capable of being detected, including drugs, hormones, proteins, polypeptides, nucleic acid molecules, pathogens (e.g., bacteria, viruses) and specific binding substances.
In a preferred form of the utility model, the assay plate is used to immobilize reagents that bind specifically to the sample.
In a preferred mode of the present utility model, the detection plate includes: display frame and detection card.
In a preferred embodiment of the present utility model, the reagent for immobilizing specific binding to a sample is immobilized on a detection card.
In a preferred mode of the present utility model, the reagent for immobilizing specifically binding to a sample includes: specific binding molecules and immunoassay reagents, and optionally reagents necessary to achieve a suitable test to produce a detectable signal.
In a preferred mode of the present utility model, the detection card may display a detection band, and the detection result is distinguished by the presence or absence of the detection band or by the number of detection bands present.
In a preferred form of the utility model, the display frame is removably attached to the test card, such as, but not limited to: the bolt is connected and connected in a sliding way.
In a preferred mode of the utility model, a plurality of fixing columns are arranged on the display frame, a plurality of fixing rings are arranged on the detection card, and the fixing columns and the fixing rings are detachably connected together in a bolt mode.
In a preferred form of the utility model, the number of fixing posts and fixing rings is uniform, typically in pairs, such as but not limited to: is set to 2, 4, 6 or 8.
In a preferred mode of the present utility model, the base includes: a liquid storage pool for containing liquid, a groove fixed on the base and a thimble positioned in the middle of the groove, and optionally, a fixing sheet and a limiting sheet for fixing the detection plate.
In a preferred form of the utility model, the liquid in the sampling tube may flow into the reservoir when the bottom of the sampling tube is pierced by the spike.
In a preferred form of the utility model, the recess is annular.
In a preferred form of the utility model, the recess has two pairs of recesses, one of which is below the thimble and the other of which is above the thimble. And in a normal state, the fixing pieces on two sides of the bottom of the sampling tube are positioned in the pits higher than the ejector pins, namely, the bottom of the sampling tube does not contact the ejector pins. When the sampling is finished and detection is needed, the sampling tube is rotated, so that the fixing pieces on two sides of the bottom of the sampling tube rotate to be lower than the concave of the ejector pin, and at the moment, the ejector pin punctures the bottom of the sampling tube, so that liquid flows into the liquid storage pool.
In a preferred mode of the utility model, after rotating 90 degrees, the fixing pieces on two sides of the bottom of the sampling tube can be rotated into the concave parts lower than the ejector pins.
In a preferred mode of the present utility model, the ejector pin may be of various shapes as long as it can pierce the bottom of the sampling tube, and preferably the ejector pin is cross-shaped.
The detection device of the utility model can be in the form of a kit or other detection available forms.
The utility model also provides a kit comprising the detection device of the utility model.
Application of the device of the utility model
The detection device of the present utility model is used to detect any existing or developed substance that can be detected, including drugs, hormones, proteins, polypeptides, nucleic acid molecules, pathogens (e.g., bacteria, viruses) and specific binding substances. In application, a suitable detection reagent capable of specifically reacting with the object to be detected is selected according to the object to be detected.
In application, the sampling tube cover is usually unscrewed, and a sampler is used for sampling; after the sampling is finished, the sampler is put back into the sampling tube, the sampling tube cover is screwed, and the sampling tube cover is uniformly shaken; rotating the sampling tube by 90 degrees, so that the fixing sheets at two sides of the bottom of the sampling tube rotate into the concave parts lower than the thimble; pressing the sampling tube, puncturing the bottom of the sampling tube by the thimble, and allowing the liquid in the sampling tube to flow into the liquid storage tank; the liquid in the liquid storage tank reacts with the detection reagent on the detection card, and the detection result is displayed on the detection board.
In a preferred form of the utility model, the test card is a test card for gastric diseases including, but not limited to: helicobacter pylori infection disease of stomach.
The detection device provided by the utility model overcomes the defect that the sampling step and the detection step are required to be carried out separately in the detection device in the prior art, can meet the detection requirement, is simple and convenient for experimental operation, and meanwhile, the detection card is easy to detach and install, so that the detection card is only required to be replaced when different detected objects are detected, and the application is wide, and the practicability and the patient compliance are high.
The device of the utility model has the following advantages:
1. the sampling step and the detection step are combined in one device, so that the device is simple and convenient for experimental operation.
2. In the preferred mode, the detachable detection card is adopted, the detachable detection card is easy to detach and install, and the detection card is only required to be replaced when different detected objects are detected, so that the application is wide, and the practicability is high.
3. In a preferred manner, when the sample is stool, patient compliance is high due to the colorless and odorless nature of the procedure used to collect the sample and detect.
The utility model will be further illustrated with reference to specific examples. It is to be understood that these examples are illustrative of the present utility model and are not intended to limit the scope of the present utility model. The experimental methods, in which specific conditions are not noted in the following examples, are generally conducted under conventional conditions or under conditions recommended by the manufacturer.
Example 1, detection apparatus of the present utility model
In this embodiment, there is provided an apparatus for collecting a sample while detecting the presence or absence of an analyte or a physical property of the sample, the apparatus comprising: the sampling tube 1, the shell 2, the detection plate 3 and the base 4. The housing is integrally formed, and one side is provided with a space for accommodating the sampling tube 1, and the other side is provided with a space for accommodating the detection plate 3. The shell 2 is detachably connected with the sampling tube 1, the detection plate 3 and the base 4.
The sampling tube 1 includes: the sampling tube comprises a sampling tube cover 101, a sampling tube body 102, a sampler 103 fixed on the sampling tube cover 101 and fixing pieces 104 fixed on two sides of the bottom of the sampling tube body 102. The sampling tube cover 101 is rotatably and detachably connected to the sampling tube body 102. The sampler 103 has a suction assembly 105 and a sampling suction tube 106. The absorbent assembly 105 may be a sponge, foam, or any suitable liquid-absorbent material. The suction assembly 105 is connected to the sampling tube cap 101 by a sampling suction tube 106. The sampling pipette 106 is used to receive and collect a sample taken.
The sample may be any liquid sample including oral fluid, saliva, blood, serum, plasma, urine, stool, spinal fluid, vaginal extract, mucus, interstitial fluid. The sample tube body 102 may be filled with a lysis solution for lysing the sample into the sample. When the sampling is completed, the sampler 103 is put back into the sampling tube body 102, and the sample can interact with the lysate in the sampling tube body 102 to crack out the tested object. The test substance may be any substance that is known or developed to be capable of being detected, including drugs, hormones, proteins, polypeptides, nucleic acid molecules, pathogens (e.g., bacteria, viruses) and specific binding substances.
The detection plate 3 includes: the display device comprises a display frame 301 and a detection card 302, wherein a plurality of fixing columns 304 are arranged on the display frame 301, a plurality of fixing rings 303 are arranged on the detection card 302, and the fixing columns 304 and the fixing rings 303 are detachably connected together in a bolt mode. The number of the fixing posts 304 and the fixing rings 303 is uniform, and is usually set in pairs, for example, 2, 4, 6 or 8. The detection card 302 may have immobilized thereon specific binding molecules and immunoassay reagents. The test card 302 may also contain the reagents necessary to perform the appropriate test to generate a detectable signal. The test card 302 may have a test strip displayed thereon, and the test results may be distinguished by the presence or absence of the test strip, or by the number of test strips present.
The base 4 includes: a liquid reservoir 401 for containing liquid, a groove 402 fixed on the base 4, a thimble 405 positioned in the middle of the groove 402, and a fixing piece 403 and a limiting piece 404 for fixing the detection plate 3. Wherein the reservoir is configured to hold a liquid, for example, when the bottom of the sampling tube is pierced by the spike, the liquid in the sampling tube may flow into the reservoir 401. The groove is annular and has two pairs of depressions, one depression being lower than the ejector pin 405 and the other depression being higher than the ejector pin 405. In a normal state, the fixing pieces 104 on both sides of the bottom of the sampling tube are located in the recess higher than the ejector pin 405, that is, the bottom of the sampling tube does not contact the ejector pin 405. When the sampling is finished and detection is required, the sampling tube is rotated, so that the fixing plates 104 on two sides of the bottom of the sampling tube are rotated to be lower than the concave parts of the ejector pins 405, and at the moment, the ejector pins 405 puncture the bottom of the sampling tube, so that liquid flows into the liquid storage tank 401. Preferably, after rotating 90 degrees, the fixing pieces on two sides of the bottom of the sampling tube can be rotated into the concave parts lower than the ejector pins 405. The thimble 405 may have various shapes as long as it can pierce the bottom of the sampling tube, and preferably the thimble 405 has a cross shape.
Example 2 method of detection Using the device of the present utility model
In this embodiment, a method for detecting using the apparatus described in embodiment 1 is provided.
The method comprises the following steps:
(1) Unscrewing the sampling tube cover 101, and sampling by using the sampler 103;
(2) After the sampling is finished, the sampler 103 is put back into the sampling tube 1, the sampling tube cover 101 is screwed, and the sampling tube is uniformly shaken;
(3) Rotating the sampling tube by 90 degrees, so that the fixing pieces 104 on two sides of the bottom of the sampling tube are rotated into the concave parts lower than the ejector pins 405;
(4) Pressing the sampling tube, and puncturing the bottom of the sampling tube by the ejector pin 405, so that the liquid in the sampling tube flows into the liquid storage tank 401;
(5) The liquid in the liquid reservoir 401 reacts with the detection reagent on the detection card 302, and the detection result is displayed on the detection plate 3.
Comparison of Performance indicators of the devices of example 3 and example 1 with the existing device
For helicobacter pylori infection of the stomach, 30 cases of fecal samples were taken, and were tested using a prior art testing device (claustrade tube from the health science and technology Co., hangzhou) with the device of example 1 of the present utility model, and the test results are shown in Table 1.
TABLE 1 Performance comparison Table of detection apparatus
Performance index Existing detection device The apparatus of example 1
Cost performance In general High height
Patient compliance Low and low High height
Compared with the detection device in the prior art, the device in the embodiment 1 of the utility model has the advantages that the operation process of taking the excrement and detecting is colorless and odorless, the compliance of patients is higher, and the detection result can be displayed in about 10 minutes, thereby being quick and convenient.
The foregoing examples illustrate only a few embodiments of the utility model and are described in detail herein without thereby limiting the scope of the utility model. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the utility model, which are all within the scope of the utility model. Accordingly, the scope of protection of the present utility model is to be determined by the appended claims. All documents referred to in this disclosure are incorporated by reference herein as if each was individually incorporated by reference.

Claims (10)

1. A device for collecting and rapidly detecting samples in a totally enclosed manner, comprising: the device comprises a sampling tube, a shell, a detection plate and a base; one side of the shell is connected with the sampling tube, the other side of the shell is connected with the detection plate, and the bottom of the shell is connected with the base;
the sampling tube includes: the device comprises a sampling tube cover, a sampling tube body, a sampler connected to the sampling tube cover and fixing sheets connected to two sides of the bottom of the sampling tube body, wherein the sampling tube body is used for containing a pyrolysis liquid for splitting a sample into a tested object;
the detection plate is used for fixing a reagent which specifically binds with a sample;
the base includes: the liquid storage pool is used for containing liquid, a groove is fixed on the base, and a thimble is positioned in the middle of the groove and can puncture the bottom of the sampling tube, wherein the groove is provided with two pairs of depressions, one pair of depressions is lower than the thimble, and the other pair of depressions is higher than the thimble; the fixing piece on the sampling tube can be placed in any pair of recesses of the groove.
2. The totally enclosed unit for collecting and rapidly testing samples according to claim 1, wherein the sampling tube cover and the sampling tube body are detachably connected together.
3. The totally enclosed unit for collecting and rapidly testing samples according to claim 2, wherein the inner side of the sampling tube cover is provided with complementary threads which can be completely engaged with the top of the sampling tube body.
4. The totally enclosed unit for collecting and rapidly testing samples according to claim 1, wherein the sampler has a suction assembly and a sampling pipette, the suction assembly being connected to the sampling tube cover through the sampling pipette.
5. The apparatus for totally enclosed collection and rapid assay of samples according to claim 1, wherein the assay plate comprises: the display frame is detachably connected with the detection card.
6. The device for collecting and rapidly detecting samples in a totally enclosed manner according to claim 5, wherein a plurality of fixing columns are arranged on the display frame, a plurality of fixing rings are arranged on the detection card, and the fixing columns and the fixing rings are detachably connected together in a bolt manner.
7. The apparatus for collecting and rapidly detecting a sample in a totally enclosed manner according to claim 6, wherein the number of the fixing posts and the fixing rings is uniform and arranged in pairs.
8. The totally enclosed unit for collecting and rapidly testing samples according to claim 1, wherein the outer casing is detachably connected with the sampling tube, the testing plate and the base.
9. The totally enclosed unit for collecting and rapidly testing samples according to claim 1, wherein the base further comprises: a fixed sheet and a limiting sheet for fixing the detection plate.
10. The apparatus for collecting and rapidly detecting a sample in a totally enclosed manner according to claim 1, wherein the ejector pin is cross-shaped and the recess is ring-shaped.
CN202320890351.9U 2023-04-19 2023-04-19 Totally enclosed type device for collecting and rapidly detecting samples Active CN220154448U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202320890351.9U CN220154448U (en) 2023-04-19 2023-04-19 Totally enclosed type device for collecting and rapidly detecting samples

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202320890351.9U CN220154448U (en) 2023-04-19 2023-04-19 Totally enclosed type device for collecting and rapidly detecting samples

Publications (1)

Publication Number Publication Date
CN220154448U true CN220154448U (en) 2023-12-08

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