CN219737266U - Noninvasive blood analysis equipment based on spectral analysis - Google Patents
Noninvasive blood analysis equipment based on spectral analysis Download PDFInfo
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- CN219737266U CN219737266U CN202321184358.5U CN202321184358U CN219737266U CN 219737266 U CN219737266 U CN 219737266U CN 202321184358 U CN202321184358 U CN 202321184358U CN 219737266 U CN219737266 U CN 219737266U
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- mounting hole
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- luminous tube
- luminotron
- light shield
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- 238000004159 blood analysis Methods 0.000 title claims abstract description 18
- 238000010183 spectrum analysis Methods 0.000 title abstract description 12
- 238000001228 spectrum Methods 0.000 claims abstract description 18
- 239000004065 semiconductor Substances 0.000 claims abstract description 14
- 229920003023 plastic Polymers 0.000 claims description 7
- 238000004611 spectroscopical analysis Methods 0.000 claims description 7
- 230000003287 optical effect Effects 0.000 claims description 5
- 239000008280 blood Substances 0.000 abstract description 37
- 210000004369 blood Anatomy 0.000 abstract description 35
- 208000035473 Communicable disease Diseases 0.000 abstract description 3
- 230000005540 biological transmission Effects 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 12
- 239000008103 glucose Substances 0.000 description 12
- 238000004820 blood count Methods 0.000 description 8
- 239000000306 component Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 230000003595 spectral effect Effects 0.000 description 6
- 102000001554 Hemoglobins Human genes 0.000 description 4
- 108010054147 Hemoglobins Proteins 0.000 description 4
- 238000010241 blood sampling Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 238000009434 installation Methods 0.000 description 4
- 210000000265 leukocyte Anatomy 0.000 description 4
- 210000003491 skin Anatomy 0.000 description 4
- 108010015776 Glucose oxidase Proteins 0.000 description 3
- 239000004366 Glucose oxidase Substances 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 229940116332 glucose oxidase Drugs 0.000 description 3
- 235000019420 glucose oxidase Nutrition 0.000 description 3
- 206010033675 panniculitis Diseases 0.000 description 3
- 210000004304 subcutaneous tissue Anatomy 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 210000004207 dermis Anatomy 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 210000003195 fascia Anatomy 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 210000000434 stratum corneum Anatomy 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 210000004276 hyalin Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- 210000001519 tissue Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The utility model discloses noninvasive blood analysis equipment based on spectrum analysis, which relates to the technical field of blood analysis and specifically comprises a circuit board, wherein a light shield mounting seat is arranged at the top of the circuit board, a light shield is fixedly connected to the top of the light shield mounting seat, a detector mounting hole is formed in the center position of the light shield, a semiconductor spectrum detector is arranged in the detector mounting hole, and the semiconductor spectrum detector is connected with the circuit board; the utility model can noninvasively detect components in blood by being close to the surface of the skin of a patient, and effectively avoids the transmission of infectious diseases.
Description
Technical Field
The utility model relates to the technical field of blood analysis, in particular to noninvasive blood analysis equipment based on spectrum analysis.
Background
At present, most blood routine detectors used in hospitals adopt a laser scattering mode, a blood sample plate is irradiated by laser, after the laser passes through the sample, the laser beam is scattered, the scattering rule of the laser beam is related to the components in the blood, and then the scattered laser is analyzed and counted to calculate and deduce the components in the blood. However, such methods of use necessarily require that a sufficient sample of the patient's blood be drawn. The cost of detection is not increased, and vein blood collection is needed for blood collection, if a patient has infectious diseases or bacteria exist in a blood collection environment, the risk of infection is not increased; of course, the conventional blood routine detector includes a photoelectric type, a capacitive type, a resistive type, and the like, in addition to the laser scattering type described above. But they all require that enough blood be collected from the patient to be analyzed.
As for blood glucose levels, it is not the case in conventional medical projects. The glucose oxidase is usually adopted to react with glucose in a blood sample, then a weak current is generated on an electrode of the blood glucose test paper, and after amplification and integral operation of an amplifier in the blood glucose meter, the content of glucose in blood can be estimated, namely the blood glucose value. Because the magnitude of the current generated by the reaction of glucose oxidase is proportional to the magnitude of the glucose concentration in blood, given a sufficient amount of glucose oxidase. Moreover, this reaction requires a trace amount of blood collection from the tip of the fingertip. However, even in the case of micro-blood collection, since invasive operations are required for the patient, any analysis of blood-related components has been conventionally performed only by performing invasive blood collection on the patient. Different methods and different detection items only differ in the amount of blood collected. To this end, we propose a non-invasive blood analysis device based on spectroscopic analysis.
Disclosure of Invention
The utility model provides non-invasive blood analysis equipment based on spectrum analysis, which solves the problem that the non-invasive blood analysis equipment can only be used for taking blood from a patient by an invasive way.
In order to achieve the above purpose, the utility model is realized by the following technical scheme:
the noninvasive blood analysis device based on spectrum analysis comprises a circuit board, wherein a light shield mounting seat is arranged at the top of the circuit board, a light shield is fixedly connected to the top of the light shield mounting seat, a detector mounting hole is formed in the center of the light shield, a semiconductor spectrum detector is arranged in the detector mounting hole, and the semiconductor spectrum detector is connected with the circuit board;
the light shield is provided with a plurality of positioning holes, the positioning holes are circumferentially distributed along the detector mounting holes, light emitting diodes are arranged in the positioning holes, the tops of the light emitting diodes are fixedly connected with optical filters, the light emitting diodes are connected with a circuit board, and one end of the circuit board is fixedly connected with a data connector.
Optionally, the positioning holes are a first light-emitting tube mounting hole, a second light-emitting tube mounting hole, a white light-emitting tube mounting hole, a third light-emitting tube mounting hole, a fourth light-emitting tube mounting hole, a fifth light-emitting tube mounting hole, a sixth light-emitting tube mounting hole and a seventh light-emitting tube mounting hole respectively;
390nm-400nm luminotrons are arranged in the first luminotron mounting hole, 425nm-430nm luminotrons are arranged in the second luminotron mounting hole, 495nm-500nm luminotrons are arranged in the third luminotron mounting hole, fourth luminotron mounting hole (620 nm-625nm luminotrons are arranged in the fifth luminotron mounting hole, 850nm luminotrons are arranged in the fifth luminotron mounting hole, 940nm luminotrons are arranged in the sixth luminotron mounting hole, and 1050nm luminotrons are arranged in the seventh luminotron mounting hole.
Optionally, the bottom fixedly connected with base of emitting diode, be connected with the luminotron pin on the base, luminotron pin and circuit board welding.
Optionally, a plurality of connecting blocks are connected on the outer wall of the light shield at equal intervals along the circumferential direction, and the connecting blocks are connected with the circuit board through bolts;
set up the fixed screw mounting hole on the connecting block, be equipped with the screw hole on the circuit board, the bolt runs through the fixed screw mounting hole and connects in the screw hole.
Optionally, the semiconductor spectrum detector comprises a transparent plastic shell, wherein a photosensitive chip is arranged in the transparent plastic shell, two sides of the photosensitive chip are connected with a plurality of chip pins, and the tail ends of the chip pins are welded with the circuit board.
The utility model has the following beneficial effects:
compared with the existing instrument, the noninvasive blood analysis equipment based on spectral analysis avoids the need of blood sampling to detect and analyze components in blood, and adopts the spectral analysis technology, and different subcutaneous tissues can be respectively measured through different spectral ranges, so that the spread of infectious diseases is avoided, and the risk of infection is effectively reduced.
Drawings
FIG. 1 is a schematic diagram of the structure of the present utility model;
FIG. 2 is a schematic diagram of a circuit board according to the present utility model;
FIG. 3 is a schematic view of a light shield according to the present utility model;
FIG. 4 is a schematic diagram of a light emitting diode according to the present utility model;
fig. 5 is a schematic structural diagram of a semiconductor spectrum detector of the present utility model.
In the figure: 1. a first light pipe mounting hole; 2. a set screw mounting hole; 3. a second luminous tube mounting hole; 4. a detector mounting hole; 5. a white multi-color light-emitting tube mounting hole; 6. a third luminous tube mounting hole; 7. a fourth luminous tube mounting hole; 8. a fifth luminous tube mounting hole; 9. a sixth luminous tube mounting hole; 10. a seventh luminous tube mounting hole; 11. a light shield mounting base; 12. screw holes; 13. a data connector; 14. a photosensitive wafer; 15. a transparent plastic housing; 16. chip pins; 17. a light filter; 18. a light emitting diode; 19. a base; 20. a luminous tube pin; 21. a light shield; 22. a circuit board; 23. and (5) connecting a block.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1 to 5, the present utility model provides a technical solution:
the noninvasive blood analysis device based on spectrum analysis comprises a circuit board 22, wherein a light shield mounting seat 11 is arranged at the top of the circuit board 22, a light shield 21 is fixedly connected to the top of the light shield mounting seat 11, a detector mounting hole 4 is formed in the center position of the light shield 21, a semiconductor spectrum detector is arranged in the detector mounting hole 4, and the semiconductor spectrum detector is connected with the circuit board 22;
the light shield 21 is provided with 8 positioning holes, the positioning holes are distributed circumferentially along the detector mounting hole 4, the positioning holes are internally provided with light emitting diodes 18, the tops of the light emitting diodes 18 are fixedly connected with optical filters 17, the light emitting diodes 18 are connected with a circuit board 22, one end of the circuit board 22 is fixedly connected with a data connector 13, and the data connector 13 is used for reading out spectral data information.
The positioning holes are respectively a first luminous tube mounting hole 1, a second luminous tube mounting hole 3, a white shading luminous tube mounting hole 5, a third luminous tube mounting hole 6, a fourth luminous tube mounting hole 7, a fifth luminous tube mounting hole 8, a sixth luminous tube mounting hole 9 and a seventh luminous tube mounting hole 10;
390nm-400nm luminotrons are arranged in the first luminotron mounting hole 1, 425nm-430nm luminotrons are arranged in the second luminotron mounting hole 3, 495nm-500nm luminotrons are arranged in the third luminotron mounting hole 6, 620nm-625nm luminotrons are arranged in the fourth luminotron mounting hole 7, 850nm luminotrons are arranged in the fifth luminotron mounting hole 8, 940nm luminotrons are arranged in the sixth luminotron mounting hole 9, and 1050nm luminotrons are arranged in the seventh luminotron mounting hole 10.
During installation and manufacture, firstly, the light emitting diodes with the optical filters in the corresponding spectral ranges are respectively installed in corresponding installation holes, then, the semiconductor spectral detector is installed in the detector installation hole 4, all the parts are welded on the circuit board 22, and the light shield 21 is fixed on the circuit board 22 through bolts, so that the installation of the device can be completed;
the utility model is mainly used for roughly analyzing the components in the blood of a patient, can realize noninvasive analysis of the concentration of hemoglobin, the red blood cell count, the white blood cell count, the platelet count and the blood glucose value, does not need blood sampling in principle, breaks the situation that the existing instrument can only detect and analyze the components in the blood after blood sampling, adopts a spectrum analysis technology, and covers the ultraviolet, visible light, near infrared and middle infrared ranges in the spectrum range, and respectively measures different subcutaneous tissues in different spectrum ranges;
the ultraviolet range spectrum mainly detects the relevant thickness of epidermis and stratum corneum, including stratum corneum, stratum hyaline layer, granular layer, spiny layer and basal layer; the visible light spectrum mainly detects skin color and measures dermis information, including blood vessels and nerves in the dermis, and is used for post calculation and interference elimination; the near infrared light and mid infrared light spectrum analysis is adopted to measure the information of the fat layer and the fascia layer, so that the fat layer and the fascia layer can penetrate more than 10mm deep into subcutaneous tissues, and the components in blood can be effectively detected;
generating light in a specific spectral range by adopting a light emitting diode and an optical filter, directly entering human tissue from the surface of the skin by using light rays with specific spectrum, and then detecting light intensity by adopting a full-spectrum semiconductor detector at an adjacent position; the method adopts a spectrum analysis mode to noninvasively detect the hemoglobin concentration, the red blood cell count, the white blood cell count, the platelet count and the blood glucose value in blood, and can detect in real time, and the sampling interval is less than 5 minutes per sampling point.
The bottom of the light emitting diode 18 is fixedly connected with a base 19, a luminous tube pin 20 is connected to the base 19, and the luminous tube pin 20 is welded with a circuit board 22.
Wherein, a plurality of connecting blocks 23 are connected on the outer wall of the light shield 21 along the circumferential direction at equal intervals, and the connecting blocks 23 are connected with the circuit board 22 through bolts;
the connecting block 23 is provided with a fixing screw mounting hole 2, the circuit board 22 is provided with a screw hole 12, and a bolt penetrates through the fixing screw mounting hole 2 and is connected in the screw hole 12.
The semiconductor spectrum detector comprises a transparent plastic shell 15, wherein a photosensitive chip 14 is arranged in the transparent plastic shell 15, the photosensitive chip 14 is an OPT101 chip, two sides of the photosensitive chip 14 are connected with a plurality of chip pins 16, and the tail ends of the chip pins 16 are welded with a circuit board 22.
In summary, the non-invasive blood analysis device based on spectroscopic analysis needs to be worn at a predetermined location, usually including the inner side of an arm, or worn on the chest, and the like, before using the present utility model, and then the blood component information of the patient at this time, including the hemoglobin concentration, the red blood cell count, the white blood cell count, the platelet count, and the blood glucose value, is measured using a conventional blood conventional analyzer and a conventional blood glucose meter. Spectral data of epidermis and subcutaneous are then acquired by the present utility model simultaneously for comparison and calibration. After the calibration is completed, the method can be normally used.
The utility model then allows for non-invasive detection of components in the patient's blood, including hemoglobin concentration, red blood cell count, white blood cell count, platelet count, and blood glucose level, during the use phase. No venous blood sampling is required. Without the need of micro-blood collection at the tip of the fingertip. The utility model is only needed to be worn on the inner side of the arm to be clung to the skin or worn on the chest to be clung to the skin, but can not be used for the abdomen, because the utility model needs to be positioned at a place where the fat layer of the patient is thinner, the data acquisition and the data calculation can be more accurate. And the position worn during measurement must be kept consistent with the position worn during calibration learning. Otherwise a recalibration operation is required.
In the description of the present utility model, it should be noted that, directions or positional relationships indicated by terms such as "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., are based on directions or positional relationships shown in the drawings, are merely for convenience of description and simplification of description, and do not indicate or imply that the apparatus or element to be referred to must have a specific direction, be constructed and operated in the specific direction, and thus should not be construed as limiting the present utility model; the terms "first," "second," "third," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance, and furthermore, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "coupled," and the like are to be construed broadly, and may be fixedly coupled, detachably coupled, or integrally coupled, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
1. A non-invasive blood analysis device based on spectroscopic analysis, comprising a circuit board (22), characterized in that: the top of the circuit board (22) is provided with a light shield mounting seat (11), the top of the light shield mounting seat (11) is fixedly connected with a light shield (21), a detector mounting hole (4) is formed in the center position of the light shield (21), a semiconductor spectrum detector is arranged in the detector mounting hole (4), and the semiconductor spectrum detector is connected with the circuit board (22);
the light shield (21) is provided with positioning holes, the number of the positioning holes is 8, the positioning holes are circumferentially distributed along the detector mounting holes (4), light emitting diodes (18) are arranged in the positioning holes, the tops of the light emitting diodes (18) are fixedly connected with optical filters (17), the light emitting diodes (18) are connected with a circuit board (22), and one end of the circuit board (22) is fixedly connected with a data connector (13).
2. A non-invasive blood analysis apparatus based on spectroscopic analysis according to claim 1, characterized in that: the positioning holes are respectively a first luminous tube mounting hole (1), a second luminous tube mounting hole (3), a white shading luminous tube mounting hole (5), a third luminous tube mounting hole (6), a fourth luminous tube mounting hole (7), a fifth luminous tube mounting hole (8), a sixth luminous tube mounting hole (9) and a seventh luminous tube mounting hole (10);
390nm-400nm luminotrons are arranged in the first luminotron mounting hole (1), 425nm-430nm luminotrons are arranged in the second luminotron mounting hole (3), 495nm-500nm luminotrons are arranged in the third luminotron mounting hole (6), 620nm-625nm luminotrons are arranged in the fourth luminotron mounting hole (7), 850nm luminotrons are arranged in the fifth luminotron mounting hole (8), 940nm luminotrons are arranged in the sixth luminotron mounting hole (9), and 1050nm luminotrons are arranged in the seventh luminotron mounting hole (10).
3. A non-invasive blood analysis apparatus based on spectroscopic analysis according to claim 1, characterized in that: the LED lamp is characterized in that a base (19) is fixedly connected to the bottom of the LED (18), a luminous tube pin (20) is connected to the base (19), and the luminous tube pin (20) is welded with a circuit board (22).
4. A non-invasive blood analysis apparatus based on spectroscopic analysis according to claim 1, characterized in that: a plurality of connecting blocks (23) are connected to the outer wall of the light shield (21) at equal intervals along the circumferential direction, and the connecting blocks (23) are connected with the circuit board (22) through bolts;
the connecting block (23) is provided with a fixed screw mounting hole (2), the circuit board (22) is provided with a screw hole (12), and a bolt penetrates through the fixed screw mounting hole (2) and is connected in the screw hole (12).
5. A non-invasive blood analysis apparatus based on spectroscopic analysis according to claim 1, characterized in that: the semiconductor spectrum detector comprises a transparent plastic shell (15), wherein a photosensitive chip (14) is arranged in the transparent plastic shell (15), two sides of the photosensitive chip (14) are connected with a plurality of chip pins (16), and the tail ends of the chip pins (16) are welded with a circuit board (22).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202321184358.5U CN219737266U (en) | 2023-05-17 | 2023-05-17 | Noninvasive blood analysis equipment based on spectral analysis |
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CN202321184358.5U CN219737266U (en) | 2023-05-17 | 2023-05-17 | Noninvasive blood analysis equipment based on spectral analysis |
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CN219737266U true CN219737266U (en) | 2023-09-22 |
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CN202321184358.5U Active CN219737266U (en) | 2023-05-17 | 2023-05-17 | Noninvasive blood analysis equipment based on spectral analysis |
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2023
- 2023-05-17 CN CN202321184358.5U patent/CN219737266U/en active Active
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