CN216375488U

CN216375488U - Kit for gene detection

Info

Publication number: CN216375488U
Application number: CN202121348659.8U
Authority: CN
Inventors: 周竹娟
Original assignee: Second Affiliated Hospital Army Medical University
Current assignee: Second Affiliated Hospital Army Medical University
Priority date: 2021-06-17
Filing date: 2021-06-17
Publication date: 2022-04-26
Anticipated expiration: 2031-06-17

Abstract

The utility model discloses a kit for gene detection, which comprises a box body, wherein a placing block is connected in the box body in a sliding manner, a strip-shaped groove is formed in the box body, the inner wall at the top and the inner wall at the bottom of the strip-shaped groove are rotatably connected with a same threaded rod, the inner wall of the strip-shaped groove is slidably connected with a sliding plate fixedly connected with one end and one side of the placing block, the sliding plate is sleeved on the outer wall of the threaded rod in a threaded manner, a first groove is formed in the box body, a transmission component for driving the threaded rod to rotate is arranged in the first groove, and four fixing plates are symmetrically and fixedly connected with the top of the box body. The shaking in the box body causes the spilling of the specimen or the reagent in the centrifuge tube or the test tube.

Description

Kit for gene detection

Technical Field

The utility model relates to the technical field of medical biology, in particular to a kit applied to gene detection.

Background

In medicine, the gene detection technology is to detect or perform gene sequencing analysis on the expression of DNA or mRNA in blood, body fluid, tissue sample or cell of a patient or an experimental animal by different methods so as to obtain the expression level of certain molecules before gene transcription or determine the abnormality of certain gene sequences under pathological conditions, and is widely applied to basic medical research or auxiliary diagnosis of clinical diseases at present. A sample for gene detection can be stored in a refrigerator for a short time or transported for a certain distance before being detected after being collected, and a centrifuge tube or a test tube containing the sample is placed on a test tube rack in a method generally adopted in the refrigerator, so that repeated movement of the sample is inevitable in the storage process, and the probability of sample pollution is increased. The specimen is usually placed in an ice box with a partition or a bracket for transportation during transportation, the common partition or the bracket does not have the function of fastening and fixing a centrifuge tube or a test tube, so that the condition of dumping is inevitable, and the condition of mixed transportation of various samples is possible due to different transportation amounts of one type of specimen at each time, so that the sealed preservation and transportation of one type of specimen cannot be realized. In addition, different specific methods adopted in gene detection may involve extraction, purification, amplification, library establishment and the like of DNA, so that the steps are multiple, and the reagents are multiple, and particularly when the number of detected samples is large, the operation of taking and placing a centrifugal tube is inconvenient, so that the phenomenon that the centrifugal tube is toppled to cause spilling of the samples or the reagents in the tube is inevitable, and the pollution is easily caused.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the defects that the existing gene detection kit has complex procedures in the processes of specimen storage, transportation and detection, has more steps, is inconvenient to take and place a centrifugal tube for multiple times and is easy to cause pollution because the centrifugal tube is easy to shake, and provides a kit for gene detection.

In order to achieve the purpose, the utility model adopts the following technical scheme:

a kit for gene detection comprises a box body, wherein a placing block is connected in the box body in a sliding manner, a strip-shaped groove is formed in the box body, the top inner wall and the bottom inner wall of the strip-shaped groove are rotatably connected with the same threaded rod, the inner wall of the strip-shaped groove is slidably connected with a sliding plate fixedly connected with one end and one side of the placing block, the sliding plate is sleeved on the outer wall of the threaded rod in a threaded manner, a first groove is formed in the box body, a transmission component for driving the threaded rod to rotate is arranged in the first groove, four fixing plates are symmetrically and fixedly connected to the top of the box body, one side, close to each other, of two fixing plates on the same side is rotatably connected with the same rotating rod, cover plates are fixedly sleeved on the outer walls of the two rotating rods, an opening and closing component for opening and closing the cover plates is arranged on the placing block, and a plurality of placing grooves are formed in the placing block, the bottom of standing groove is fixed and is provided with the arc rubber pad, be provided with in the standing groove and press from both sides the fixed subassembly of tight fixed to the test tube. According to the test tube or the centrifuging tube that different specifications were used to different experimental specimen of splendid attire or reagent, can set up the standing groove of different specifications according to test tube or centrifuging tube size, the gene testing of different specifications is named with the specification classification of standing groove and is used kit.

Preferably, the transmission assembly comprises a same rotating shaft rotatably connected with the inner walls of the two sides of the first groove, a first helical gear is fixedly sleeved on the outer wall of the rotating shaft, and a second helical gear meshed with the first helical gear is fixedly sleeved on the bottom inner wall of the threaded rod penetrating through the strip-shaped groove and extending into the first groove.

Preferably, one end of the rotating shaft penetrates through the inner wall of one side of the first groove, extends to the outer side of the box body and is fixedly sleeved with a hand wheel, and an anti-skidding sleeve is sleeved on a holding rod of the hand wheel.

Preferably, the opening and closing assembly comprises two ejector rods which are symmetrically and fixedly connected with the top of the placing block, the top of each ejector rod is rotatably connected with a sliding block, and the two sliding blocks are respectively in sliding connection with the bottoms of the two cover plates.

Preferably, the bottom of the two cover plates is fixedly connected with a sealing ring, and the sealing ring is made of rubber.

Preferably, the fixed subassembly includes the second recess that the inner wall of standing groove was seted up, the inner wall sliding connection of second recess has the arc pinch-off blades, the same spring of one side of arc pinch-off blades and the inner wall fixedly connected with of second recess, the concave side fixedly connected with silica gel plate of arc pinch-off blades.

Compared with the prior art, the utility model has the beneficial effects that:

1. according to the utility model, when a centrifugal tube or a test tube needs to be placed into the box body, the hand wheel is manually rotated, the rotation of the hand wheel drives the threaded rod to rotate, the rotation of the threaded rod drives the sliding plate to slide, the sliding of the sliding plate drives the placing block to slide, the sliding of the placing block drives the ejector rod to move, the movement of the ejector rod drives the cover plates to rotate, and the opposite rotation of the two cover plates opens the seal on the top of the box body;

2. in the utility model, after the sealing of the box body is opened, the placing block just slides to the top and the top of the box body to be positioned at the same horizontal plane, so that the placing work of a centrifugal tube or a test tube is convenient, and the centrifugal tube or the test tube filled with a sample or a reagent for extracting gene detection can be inserted into the placing groove;

3. according to the centrifugal tube or test tube placing device, the arc-shaped clamping plate is used for clamping and fixing the centrifugal tube or test tube under the elastic force of the spring, so that the centrifugal tube or test tube is prevented from being spilled due to shaking in the placing groove, the arc-shaped rubber pad arranged at the bottom of the placing groove has the buffer protection effect on the bottom of the centrifugal tube or test tube, after the centrifugal tube or test tube is placed, the placing block is lowered to the initial position by reversely rotating the hand wheel 8, and the box body is sealed again through the cover plate.

The centrifugal tube or test tube box is simple in structure and convenient to use, the placing block is lifted when the box body is opened, a centrifugal tube or a test tube is convenient to take and place, the centrifugal tube or test tube box has the function of clamping and fixing the centrifugal tube or test tube, and the phenomenon that the centrifugal tube or test tube is shaken in the box body after being placed to cause spilling of a sample or a reagent in the centrifugal tube or test tube and cause pollution is avoided.

Drawings

FIG. 1 is a schematic sectional view of a main view of a kit for gene detection according to the present invention;

FIG. 2 is an enlarged schematic view of part A of a kit for gene detection according to the present invention;

FIG. 3 is a schematic three-dimensional structure diagram of an arc-shaped clamping plate of the kit for gene detection according to the present invention.

In the figure: 1. a box body; 2. placing the blocks; 3. an arc-shaped rubber pad; 4. a placement groove; 5. a first groove; 6. a first helical gear; 7. a rotating shaft; 8. a hand wheel; 9. a second helical gear; 10. a sliding plate; 11. a threaded rod; 12. a strip-shaped groove; 13. a top rod; 14. a slider; 15. a cover plate; 16. an arc-shaped clamping plate; 17. a second groove; 18. a spring; 19. a seal ring; 20. rotating the rod; 21. and (7) fixing the plate.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

Example one

Referring to fig. 1-3, a kit for gene detection, comprising a box body 1, a placing block 2 slidably connected in the box body 1, a strip-shaped groove 12 formed in the box body 1, a same threaded rod 11 rotatably connected to the top inner wall and the bottom inner wall of the strip-shaped groove 12, a sliding plate 10 fixedly connected to one end and one side of the placing block 2 and slidably connected to the inner wall of the strip-shaped groove 12, a first groove 5 formed in the box body 1, a transmission assembly for driving the threaded rod 11 to rotate and disposed in the first groove 5, four fixing plates 21 symmetrically and fixedly connected to the top of the box body 1, a same rotating rod 20 rotatably connected to the side of the two fixing plates 21 on the same side close to each other, cover plates 15 fixedly sleeved on the outer walls of the two rotating rods 20, and an opening and closing assembly for opening and closing the cover plates 15 disposed on the placing block 2, place and seted up a plurality of standing grooves 4 on the piece 2, the fixed arc rubber pad 3 that is provided with in bottom of standing groove 4 is provided with in the standing groove 4 and presss from both sides tight fixed subassembly to the test tube.

Example two

The embodiment is improved on the basis of the first embodiment: the transmission assembly includes the same axis of rotation 7 that the both sides inner wall of first recess 5 rotated the connection, fixed cover is equipped with first helical gear 6 on the outer wall of axis of rotation 7, the bottom inner wall that the bottom of threaded rod 11 runs through bar groove 12 extends to in first recess 5 and fixed cover is equipped with second helical gear 9 with first helical gear 6 engaged with, one side inner wall that one end of axis of rotation 7 runs through first recess 5 extends to the outside of box body 1 and fixed cover is equipped with hand wheel 8, the cover is equipped with the antiskid cover on hand wheel 8's the holding rod.

EXAMPLE III

The embodiment is improved on the basis of the first embodiment: the subassembly that opens and shuts is including placing two ejector pins 13 of the symmetrical fixed connection in top of piece 2, the top of ejector pin 13 is rotated and is connected with slider 14, two sliders 14 respectively with two apron 15's bottom sliding connection, the equal fixedly connected with sealing washer 19 in bottom of two apron 15, the material of sealing washer 19 is rubber, fixed subassembly includes the second recess 17 that the inner wall of standing groove 4 was seted up, the inner wall sliding connection of second recess 17 has arc pinch-off blades 16, one side of arc pinch-off blades 16 and the same spring 18 of the inner wall fixedly connected with of second recess 17, the concave side fixedly connected with silica gel plate of arc pinch-off blades 16.

The working principle is as follows: when a centrifugal tube or a test tube is required to be placed into the box body 1, a hand wheel 8 is manually rotated, the rotation of the hand wheel 8 drives a rotation shaft 7 to rotate, the rotation of the rotation shaft 7 drives a first bevel gear 6 to rotate, the rotation of the first bevel gear 6 drives a second bevel gear 9 to rotate, the rotation of the second bevel gear 9 drives a threaded rod 11 to rotate, the rotation of the threaded rod 11 drives a sliding plate 10 to slide, the sliding plate 10 drives a placing block 2 to slide, the sliding of the placing block 2 drives an ejector rod 13 to move, the movement of the ejector rod 13 drives a cover plate 15 to rotate, the opposite rotation of the two cover plates 15 opens the seal of the top of the box body 1, after the seal of the box body 1 is opened, the placing block 2 just slides to the top and the top of the box body 1 to be positioned at the same horizontal plane, the placing work of the centrifugal tube or the test tube is convenient, at the moment, the centrifugal tube or the test tube filled with a sample or reagent for gene detection can be inserted into a placing groove 4, insert the back, arc pinch-off blades 16 is under spring 18's elasticity, and arc pinch-off blades 16 realizes that it is fixed to the centrifuging tube or test tube realization clamp, prevents that it from taking place to rock at standing groove 4 and causing spilling of sample or reagent, and arc rubber pad 3 that standing groove 4 bottoms set up has carries out buffer protection to centrifuging tube or test tube bottom, and after placing, the reverse rotation hand wheel 8 will place piece 2 and fall to initial position to it can to seal once more to box body 1 through apron 15.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims

1. A kit for gene detection comprises a box body (1) and is characterized in that a placing block (2) is connected in the box body (1) in a sliding mode, a strip-shaped groove (12) is formed in the box body (1), the top inner wall and the bottom inner wall of the strip-shaped groove (12) are rotatably connected with the same threaded rod (11), the inner wall of the strip-shaped groove (12) is slidably connected with a sliding plate (10) with one end fixedly connected with one side of the placing block (2), the sliding plate (10) is sleeved on the outer wall of the threaded rod (11) in a threaded mode, a first groove (5) is formed in the box body (1), a transmission assembly for driving the threaded rod (11) to rotate is arranged in the first groove (5), four fixing plates (21) are symmetrically and fixedly connected to the top of the box body (1), one side, close to each other, of the two fixing plates (21) is rotatably connected with the same rotating rod (20), two all fixed cover is equipped with apron (15) on the outer wall of dwang (20), place and be provided with the subassembly that opens and shuts of apron (15) on piece (2), place and seted up a plurality of standing grooves (4) on piece (2), the fixed arc rubber pad (3) that are provided with in bottom of standing groove (4), be provided with in standing groove (4) and press from both sides the fixed subassembly that presss from both sides tight fixed to the test tube.

2. The kit for gene detection according to claim 1, wherein the transmission assembly comprises a same rotating shaft (7) rotatably connected with the inner walls of the two sides of the first groove (5), the outer wall of the rotating shaft (7) is fixedly sleeved with a first helical gear (6), the bottom of the threaded rod (11) extends into the first groove (5) through the inner wall of the bottom of the strip-shaped groove (12) and is fixedly sleeved with a second helical gear (9) engaged with the first helical gear (6).

3. The kit for gene detection according to claim 2, wherein one end of the rotation shaft (7) extends to the outer side of the case body (1) through one side inner wall of the first groove (5) and is fixedly sleeved with a hand wheel (8), and a grip of the hand wheel (8) is sleeved with an anti-slip sleeve.

4. The kit for gene detection according to claim 1, wherein the opening and closing assembly comprises two ejector rods (13) symmetrically and fixedly connected with the top of the placing block (2), the top of each ejector rod (13) is rotatably connected with a sliding block (14), and the two sliding blocks (14) are respectively connected with the bottoms of the two cover plates (15) in a sliding manner.

5. The gene detection kit according to claim 1, wherein the bottom of each of the two cover plates (15) is fixedly connected with a sealing ring (19), and the sealing rings (19) are made of rubber.

6. The kit for gene detection according to claim 1, wherein the fixing component comprises a second groove (17) formed in the inner wall of the placing groove (4), an arc-shaped clamping plate (16) is slidably connected to the inner wall of the second groove (17), the same spring (18) is fixedly connected to one side of the arc-shaped clamping plate (16) and the inner wall of the second groove (17), and a silica gel plate is fixedly connected to the concave side of the arc-shaped clamping plate (16).