CN211836538U - Solid-liquid separation device for protein purification - Google Patents
Solid-liquid separation device for protein purification Download PDFInfo
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- CN211836538U CN211836538U CN202020217217.9U CN202020217217U CN211836538U CN 211836538 U CN211836538 U CN 211836538U CN 202020217217 U CN202020217217 U CN 202020217217U CN 211836538 U CN211836538 U CN 211836538U
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Abstract
The utility model discloses a solid-liquid separation device for protein purification, which comprises a plate-frame filter press and is used for carrying out solid-liquid separation of protein; the leakage recovery box also comprises an upper opening structure; and the support piece is fixed in the leaked liquid recovery box, the plate-and-frame filter press is supported and fixed in the leaked liquid recovery box through the support piece, and leaked liquid of the plate-and-frame filter press is collected by the leaked liquid recovery box. The utility model has the advantages of simple structure, and is simple and convenient to manufacture and install. The leaked liquid is collected through the leaked liquid recovery box, so that the waste of the material liquid and the pollution to the ground are effectively avoided; the support piece arranged in the leaked liquid recovery box can fix and support the plate and frame filter press, so that the plate and frame filter press is prevented from being polluted by feed liquid stored in the leaked liquid recovery box, and the normal work of the plate and frame filter press is ensured; in addition, the leakage recovery box can also accept waste residues, so that the plate and frame filter press can be cleaned in situ without disassembly, manpower is saved, labor cost is reduced, and working efficiency is improved.
Description
Technical Field
The utility model belongs to the technical field of the protein purification technique and specifically relates to a protein purification is with solid, liquid separation equipment is related to.
Background
The plate-frame filter press is an intermittent solid-liquid separation device, and is a machine which is characterized in that filter plates and filter frames are arranged to form filter chambers, feed liquid is fed into each filter chamber under the pressure action of a feed delivery pump, and solid and liquid are separated through a filter medium; due to the characteristics of the plate-frame filter press, the method is widely applied to the field of protein purification for solid-liquid separation, has the advantages of good separation effect, wide application range, simple operation, low investment and the like, and has incomparable superiority. However, when the existing plate-and-frame filter press is used for solid-liquid separation and filtration treatment, the problem of liquid leakage often occurs, the liquid leakage can cause material waste, the ground can be polluted or polluted, and workers are required to clean the filter press; in addition, when current plate and frame filter press cleared up after the completion of filtering, because there is not any device of accepting the waste liquid, lead to dismantling to clear up, the operation is very troublesome, and the cost of labor risees greatly, and work efficiency is very low.
Disclosure of Invention
The utility model aims to provide a can effectively collect the protein purification of weeping or waste liquid and use solid, liquid separation equipment.
In order to achieve the above purpose, the utility model can adopt the following technical proposal:
the solid-liquid separation device for protein purification comprises a plate-frame filter press, which is used for solid-liquid separation of protein; the leakage recovery box also comprises an upper opening structure; and the support piece is fixed in the leaked liquid recovery box, the plate and frame filter press is supported and fixed in the leaked liquid recovery box through the support piece, and leaked liquid of the plate and frame filter press is collected by the leaked liquid recovery box.
The leakage recovery box is provided with a drainage component for draining accumulated liquid stored in the leakage recovery box; the liquid discharge component is a liquid discharge pipe which is hermetically communicated with the bottom of the side wall of the leakage recovery box; and a liquid discharge valve positioned outside the leaked liquid recovery box is arranged on the liquid discharge pipe.
The inner bottom surface of the leakage recovery box is inclined downwards towards the liquid inlet of the liquid discharge pipe.
The support piece comprises a plurality of pairs of longitudinal supporting legs which are arranged at intervals along the length direction of the leakage recovery box and are fixedly supported on the inner bottom surface of the leakage recovery box, and a horizontal supporting plate which is fixed at the upper end of each longitudinal supporting leg and is used for supporting the plate-frame filter press, wherein leakage holes are uniformly distributed in the horizontal supporting plate.
An upper cover is arranged on an opening of the leakage recovery box; the upper cover is a pair of cover plates hinged to the edges of the opposite sides of the opening of the leakage recovery box, and handles which are convenient to open and close are arranged on the outer side surfaces of the two cover plates.
The utility model has the advantages of simple structure, and is simple and convenient to manufacture and install. The leaked liquid of the plate-and-frame filter press is collected through the leaked liquid recovery box, so that the waste of the material liquid and the pollution to the ground are effectively avoided; the support piece arranged in the leaked liquid recovery box can fix and support the plate and frame filter press, so that the plate and frame filter press is prevented from being polluted by feed liquid stored in the leaked liquid recovery box, and the normal work of the plate and frame filter press is ensured; in addition, the leakage recovery box can also accept waste residues, so that the plate and frame filter press can be cleaned in situ without disassembly, manpower is saved, labor cost is reduced, and working efficiency is improved.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Detailed Description
As shown in fig. 1, the solid-liquid separation device for protein purification according to the present invention comprises a plate and frame filter press 1 for performing solid-liquid separation of protein, and a leaked liquid recovery tank 2 having an upper opening structure, wherein a support member is fixedly arranged in the leaked liquid recovery tank 2, the plate and frame filter press 1 is supported and fixed in the leaked liquid recovery tank 2 through the support member, and the leaked liquid of the plate and frame filter press 1 is collected by the leaked liquid recovery tank 2; specifically, the supporting piece comprises a plurality of pairs of longitudinal supporting legs 3 which are arranged at intervals along the length direction of the leakage recovery box 2 and are fixedly supported on the inner bottom surface of the leakage recovery box, and a horizontal supporting plate 4 which is fixed at the upper end of each longitudinal supporting leg 3 and is used for supporting the plate-and-frame filter press 1, wherein leakage holes 5 which are convenient for liquid to fall are uniformly distributed in the horizontal supporting plate 4; when the plate and frame filter press 1 is used for filtering and separating protein solids and liquid, leaked liquid can fall into the leaked liquid recovery tank 2 through the leaked liquid holes 5 on the horizontal supporting plate 4 and be accumulated.
In order to facilitate the discharge of accumulated liquid stored in the leaked liquid recovery tank 2, a liquid discharge part is arranged on the leaked liquid recovery tank 2; specifically, the drainage component can be a drainage pipe 6 which is hermetically communicated with the bottom of the side wall of the leakage recovery box 2, a drainage valve 7 which is positioned on the outer side of the leakage recovery box 2 is arranged on the drainage pipe 6, and accumulated liquid in the leakage recovery box 2 can be easily drained by operating the drainage valve 7; in order to better discharge the accumulated liquid out of the box, the inner bottom surface of the leakage recovery box 2 is inclined downwards towards the liquid inlet of the liquid discharge pipe 6.
In addition, in order to avoid the pollution of the inner cavities of the plate and frame filter press 1 and the leaked liquid recovery tank 2 when the device is in standing, an upper cover is arranged on the opening of the leaked liquid recovery tank 2, the opening of the leaked liquid recovery tank 2 can be buckled through the upper cover, and the sealing performance of the leaked liquid recovery tank 2 is enhanced. The upper cover can be a pair of cover plates 8 hinged to the edges of the opposite sides of the opening of the leakage recovery box 2, and handles 9 convenient to open and close are arranged on the outer side surfaces of the two cover plates 8; of course, the cover plates 8 may be divided into a plurality of pairs according to the specific length of the leakage recovery tank 2, and arranged side by side on the opening of the leakage recovery tank 2.
During the use, only need open apron 8, operate plate and frame filter press 1 according to the operation needs, at the in-process of plate and frame filter press 1 work, the weeping can directly fall to in the weeping collection box 2, when the weeping in the weeping collection box 2 stores up a certain amount, alright open flowing back valve 7, retrieve the weeping and recycle. After the protein purification solid-liquid separation is finished, the protein purification solid-liquid separation device can be cleaned under the condition that the plate-frame type filter press 1 is not disassembled, the cleaned waste liquid is also accumulated in the leaked liquid recovery box 2 and is discharged by the liquid discharge pipe 6, and the residual filter residue can be easily collected and cleaned out of the leaked liquid recovery box 2.
Claims (8)
1. A solid-liquid separation apparatus for protein purification comprises
The plate and frame filter press is used for carrying out solid-liquid separation on the protein;
the method is characterized in that: also comprises
A leakage recovery tank with an upper opening structure; and
and the support piece is fixed in the leaked liquid recovery box, the plate and frame filter press is supported and fixed in the leaked liquid recovery box through the support piece, and leaked liquid of the plate and frame filter press is collected by the leaked liquid recovery box.
2. The solid-liquid separation apparatus for protein purification according to claim 1, wherein: and the leakage recovery box is provided with a liquid drainage component for draining accumulated liquid stored in the leakage recovery box.
3. The solid-liquid separation apparatus for protein purification according to claim 2, wherein: the liquid discharge component is a liquid discharge pipe which is hermetically communicated with the bottom of the side wall of the leakage recovery box.
4. The solid-liquid separation apparatus for protein purification according to claim 3, wherein: and a liquid discharge valve positioned outside the leaked liquid recovery box is arranged on the liquid discharge pipe.
5. The solid-liquid separation apparatus for protein purification according to claim 3, wherein: the inner bottom surface of the leakage recovery box is inclined downwards towards the liquid inlet of the liquid discharge pipe.
6. The solid-liquid separation apparatus for protein purification according to claim 1, wherein: the support piece comprises a plurality of pairs of longitudinal supporting legs which are arranged at intervals along the length direction of the leakage recovery box and are fixedly supported on the inner bottom surface of the leakage recovery box, and a horizontal supporting plate which is fixed at the upper end of each longitudinal supporting leg and is used for supporting the plate-frame filter press, wherein leakage holes are uniformly distributed in the horizontal supporting plate.
7. The solid-liquid separation apparatus for protein purification according to claim 1, wherein: an upper cover is arranged on the opening of the leakage recovery box.
8. The solid-liquid separation apparatus for protein purification according to claim 7, wherein: the upper cover is a pair of cover plates hinged to the edges of the opposite sides of the opening of the leakage recovery box, and handles which are convenient to open and close are arranged on the outer side surfaces of the two cover plates.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020217217.9U CN211836538U (en) | 2020-02-27 | 2020-02-27 | Solid-liquid separation device for protein purification |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020217217.9U CN211836538U (en) | 2020-02-27 | 2020-02-27 | Solid-liquid separation device for protein purification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211836538U true CN211836538U (en) | 2020-11-03 |
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ID=73247451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020217217.9U Active CN211836538U (en) | 2020-02-27 | 2020-02-27 | Solid-liquid separation device for protein purification |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN211836538U (en) |
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2020
- 2020-02-27 CN CN202020217217.9U patent/CN211836538U/en active Active
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