CN209644898U - A kind of packaged type magnetic resonance imaging system - Google Patents
A kind of packaged type magnetic resonance imaging system Download PDFInfo
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- CN209644898U CN209644898U CN201822090595.0U CN201822090595U CN209644898U CN 209644898 U CN209644898 U CN 209644898U CN 201822090595 U CN201822090595 U CN 201822090595U CN 209644898 U CN209644898 U CN 209644898U
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- 238000002595 magnetic resonance imaging Methods 0.000 title claims abstract description 45
- 238000005481 NMR spectroscopy Methods 0.000 claims abstract description 53
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- 238000001228 spectrum Methods 0.000 claims 1
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- 238000003384 imaging method Methods 0.000 description 10
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
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- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 2
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Abstract
The utility model relates to a kind of packaged type magnetic resonance imaging system, which includes control device, wireless transmitter receiver unit, nuclear magnetic resonance spectrometer, radio frequency system, gradient system, magnet system and movable supporting frame;Control device is for emitting pulse train and being sent to nuclear magnetic resonance spectrometer through wireless transmitter receiver unit;Nuclear magnetic resonance spectrometer is for receiving pulse train and generating digital RF transmitting signal and digit gradient signal, and digital RF transmitting signal is sent to radio frequency system after processing, and digit gradient signal is sent to gradient system after processing;In the NMR signal being tested, which is transmitted to nuclear magnetic resonance spectrometer after being acquired by radio frequency system, while being uploaded to control device through wireless transmitter receiver unit for radio frequency system, gradient system and magnet system collective effect;Movable supporting frame is used to support fixed above-mentioned each device, realizes the movement of magnetic resonance imaging system.
Description
Technical field
The utility model is to belong to nuclear magnetic resonance technique field about a kind of packaged type magnetic resonance imaging system.
Background technique
Magnetic resonance imaging (Magnetic Resonance Imaging, MRI) is used as a kind of Non-invasive detection means, due to it
The high significant properties of soft tissue contrast is studied in biological living research, modern medical diagnosis, physical chemistry and material science etc.
In play an important role.However, high field MRI instrument is all made of superconducting magnet in the prior art, though it can obtain highly sensitive and high
The magnetic resonance signal of resolution ratio, but bulky, weight is weighed and be must be mounted in relatively harsh running environment, it can not
Meet the requirement for carrying out instant on-site test under biological living experiment and outdoor environment to toy or human body.
As shown in Figure 1, routine MRI instrument is usually mainly by magnet system, gradient system, radio frequency system and nuclear magnetic resonance spectrometer
It is constituted Deng part.Magnet system and gradient system provide the nonlinear magnetostatic field on tri- directions X, Y, Z, so that in subject not
Spin angular momentaum with position is the nuclear magnetization of odd number, spiral with specific frequency around itself magnetization vector direction
Precession;The transmitting coil in radio frequency system is controlled by the controller in nuclear magnetic resonance spectrometer, so that it is generated RF magnetic field, to specific
The nuclear magnetization vector of frequency is disturbed, to excite subject, the body being excited generates MRI signal, total by magnetic
The receiving coil for spectrometer control radio frequency system of shaking receives;Nuclear magnetic resonance spectrometer amplifies the signal received, and passes through analog to digital conversion
Device acquisition is stored in memory.
In order to get rid of harsh running environment, desk-top or portable MRI instrument in recent years, which generally passes through, changes magnet system
System structure is permanent magnet combination, achievees the purpose that miniaturization or portable.But since the technology that magnetizes in the market is limited, system sheet
Body magnetic field strength is not high, and uniformity is unable to get guarantee.These hardware problems cause desk-top or portable MRI instrument to obtain
Signal resolution and sensitivity are lower, and can not be diffused imaging research.In addition, generally being adopted to reach high-resolution
Magnetic field strength is improved with compared with muti-piece permanent magnet, causes this quasi-instrument heavy, mobile performance is poor, and the occasion studied is mostly religion
Environment is learned, Bioexperiment is significantly limited.Moreover, currently a popular desk-top or portable MRI instrument only detects mostly in the market1H atom core can not carry out the measurement in relation to metabolism aspect to measured body.
Utility model content
In view of the above problems, the object of the present invention is to provide one kind can real-time perfoming indoor and outdoor MRI detection, and energy
Enough realize the packaged type magnetic resonance imaging system of high-resolution and the detection of diffusion NMR resonance image-forming.
To achieve the above object, the utility model takes following technical scheme: a kind of packaged type magnetic resonance imaging system,
It is characterized in that, the magnetic resonance imaging system includes control device, wireless transmitter receiver unit, nuclear magnetic resonance spectrometer, radio frequency system
System, gradient system, magnet system and movable supporting frame;The control device is for emitting pulse train and through the wireless hair
It penetrates receiving unit and is sent to the nuclear magnetic resonance spectrometer;The nuclear magnetic resonance spectrometer is penetrated for receiving pulse train and generating number
It takes place frequently and penetrates signal and digit gradient signal, the digital RF transmitting signal is sent to the radio frequency system after processing, described
Digit gradient signal is sent to gradient system after processing;The radio frequency system, gradient system and magnet system collective effect in
The NMR signal being tested, the NMR signal are transmitted to the nuclear-magnetism after being acquired by the radio frequency system and are total to
Shake spectrometer, while being uploaded to the control device through the wireless transmitter receiver unit;The movable supporting frame is used to support solid
Fixed above-mentioned control device, wireless transmitter receiver unit, nuclear magnetic resonance spectrometer, radio frequency system, gradient system and magnet system, are realized
The movement of the magnetic resonance imaging system.
Above-mentioned packaged type magnetic resonance imaging system, it is preferable that the movable supporting frame uses Liftable type trolley, institute
Stating Liftable type trolley includes bottom plate, lifting platform and idler wheel, and a rolling is fixedly installed in the bottom four corners of the bottom plate respectively
It takes turns, the bottom of the lifting platform is fixedly connected at the top of the bottom plate, the control dress is fixedly installed in the top of the lifting platform
It sets and magnet system, gradient system and radio frequency system, institute is fixedly installed in nuclear magnetic resonance spectrometer, the top of the nuclear magnetic resonance spectrometer
The driving device for stating lifting platform is electrically connected the control device, for controlling the lifting of the lifting platform.
Above-mentioned packaged type magnetic resonance imaging system, it is preferable that the movable supporting frame uses arm type bracket, the hand
Arm-type bracket includes two mechanical arms for fixing with wall, and the magnet system is fixedly installed on a mechanical arm
The control device and nuclear magnetic resonance spectrometer is fixedly installed on another mechanical arm in system, gradient system and radio frequency system.
Above-mentioned packaged type magnetic resonance imaging system, it is preferable that the magnet system includes magnet skeleton disk, the magnet
Eight pieces of permanent magnet blocks are arranged in the annular space inner circumferential interval of skeleton disk, and the inner ring fixed setting of the magnet skeleton disk is passive even
Field unit, the passive shimming unit are used in magnet chamber guarantee transverse plane field homogeneity by adjusting the distance of magnet
Degree is horizontal.
Above-mentioned packaged type magnetic resonance imaging system, it is preferable that the radio frequency system includes 12 layers of radio-frequency coil around to edge
Be divided into G on cylinder axial direction between every two layers of radio-frequency coil, the height of each radio-frequency coil from top to bottom according to
Secondary is that H6, H5, H4, H3, H2, H1, H1, H2, H3, H4, H5, H6 protect by adjusting parameter H1, H2, H3, H4, H5, H6 and G
Demonstrate,prove the intracorporal RF magnetic field uniformity levels of chamber.
Because the utility model adopts the above technical scheme, it has the following advantages:
1, the utility model realizes the function of indoor and outdoor real-time perfoming MRI detection in the case where guaranteeing that field system is stablized
Can, it can realize that high-resolution and diffusion NMR resonance image-forming are visited by the magnetostatic field gradient and radio-frequency coil that generate after function optimization
Survey, compared with presently, there are desk-top or portable MRI device in imaging function, resolution ratio and flexibility have significant enhancement;
2, the utility model is given due to being provided with Moveable support and is tested big convenience, changes traditional MRI and surveys
Amount mode, this instrument have the applicability under biological living experiment and indoor and outdoor working environment, such as to movement field player
The damage check of brain and four limbs is very important, and when the mobile difficulty of sportsman's (or subject), can pass through packaged type
Bracket mobile MRI instrument detects it;
3, under the premise of guaranteeing moveable, the utility model is using the radio-frequency coil winding mode for becoming spacing, for normal
The lesion that does not observe of rule structure imaging has higher susceptibility and special;
4, the utility model is by the integrated spectrometer of wireless control, solves Conventional MRI systems to space and position
Limited, no matching is required special purpose computer further decreases the cost of system, the convenient degree and flexibility that raising system uses;
To sum up, the utility model is not necessarily to additional magnetic shielding system, is suitable for without the expensive cooling unit such as liquid helium, liquid nitrogen
Small animal imaging and medical imaging under indoor and outdoor surroundings.
Detailed description of the invention
Fig. 1 is conventional MRI Image-forming instrument structural block diagram;
Fig. 2 is the principles of the present invention schematic diagram;
Fig. 3 is one structural schematic diagram of embodiment of the movable supporting frame of the utility model;
Fig. 4 is two structural schematic diagram of embodiment of the movable supporting frame of the utility model;
Fig. 5 is the transversely arranged plan view of magnet system of the utility model;
Fig. 6 is the gradient system circumferentially expanded view of the utility model, wherein abscissa theta is the angle of spread, and W1 is
Gradient coil member width, H1 are gradient coil member height;
Fig. 7 is the radio frequency system circumferentially expanded view of the utility model, wherein abscissa theta is the angle of spread.
Specific embodiment
It is practical new below in conjunction with this to keep the objectives, technical solutions, and advantages of the embodiments of the present invention clearer
Attached drawing in type embodiment, the technical scheme in the utility model embodiment is clearly and completely described, it is clear that is retouched
The embodiment stated is a part of the embodiment of the utility model, instead of all the embodiments.Based on the reality in the utility model
Apply example, those of ordinary skill in the art's every other embodiment obtained without making creative work, all
Belong to the range of the utility model protection.
In order to enable the principle of packaged type magnetic resonance imaging system provided by the utility model is clearer, below to this
The basic principle for the nuclear magnetic resonance that utility model is related to is illustrated.
Magnet system: magnetostatic field needed for magnet system provides MRI determines the signal-to-noise ratio of NMR signal.Magnet material
Usually there are permanent magnet and two kinds of superconductor.Superconductor is commonly used in High-Field instrument chemistry spectrum analysis in medical imaging and laboratory
In.The superconductor developed at present is both needed to keep magnet temperature constant using liquid helium and liquid nitrogen;Permanent magnet is basically used for low field nuclear-magnetism
Resonance measuring is more suitable for mobility magnetic resonance system.Material, number and the arrangement of permanent magnet magnetic patch decide magnetostatic field
Intensity.
Gradient system: magnetic resonance gradient is made of gradient coil, can produce the magnetic of the linear change along space a direction
, it completes the editor to nuclear magnetic resonance information in specific dimension and realizes imaging function.Usual gradient system includes three pairs of lines
Circle is used for layer position, phase and frequency editor for generating the gradient magnetic in three orthogonal directions.The coiling side of coil
Formula determines the linear magnetic field uniformity and length of generation.
Radio-frequency pulse: radio-frequency pulse is electromagnetic signal, is usually generated by coil.The magnetic field that radio-frequency pulse generates is radio-frequency magnetic
Field B1.The direction of RF magnetic field is vertical with magnetostatic field direction, realizes that the switching to the magnetization vector formed in magnetostatic field operates.
The intensity of RF magnetic field is related to the circular mode of coil.The utility model relates to coil design scheme be based on solenoid type
Winding, wherein genetic algorithm optimization is taken at helical interval.
As shown in Figure 2 and Figure 3, packaged type magnetic resonance imaging system provided by the utility model includes control device 1, nothing
Line emits receiving unit 2, nuclear magnetic resonance spectrometer 3, magnet system 4, gradient system 5, radio frequency system 6 and movable supporting frame 7.
Control device 1 is for emitting pulse train and being sent to nuclear magnetic resonance spectrometer 3 through wireless transmitter receiver unit 2;
Nuclear magnetic resonance spectrometer 3 is for receiving pulse train and generating digital RF transmitting signal and digit gradient signal, number
Word radio frequency transmissions are after the power amplifier amplification of inside configuration, by being sent to after tuned cell and matching unit processing
Radio frequency system 6, digit gradient signal are sent to gradient system 5 after the power amplifier amplification of inside configuration;Radio frequency system 6,
Gradient system 5 and 4 collective effect of magnet system are in the NMR signal being tested;
The NMR signal is transmitted to nuclear magnetic resonance spectrometer 3 after being acquired by radio frequency system 6, while through wireless transmitter receiver
Unit 2 is uploaded to control device 1;
Movable supporting frame 7 is used to support fixed control device 1, wireless transmitter receiver unit 2, nuclear magnetic resonance spectrometer 3, magnet
System 4, gradient system 5 and radio frequency system 6, realize the movement of magnetic resonance imaging system.
Movable supporting frame is for placing control device 1, wireless transmitter receiver unit 2, nuclear magnetic resonance spectrometer 3, magnet system
4, gradient system 5 and radio frequency system 6, realize the movement of magnetic resonance imaging system.
In above-described embodiment, it is preferable that as shown in figure 3, movable supporting frame 7 can use Liftable type trolley, especially
Suitable for injury gained in sports on-site test and feedback on sports ground, Liftable type trolley 7 includes bottom plate 71, lifting platform 72 and rolling
An idler wheel 73, the bottom of the top fixed setting lifting platform 72 of bottom plate 71 is fixedly installed in wheel 73, the bottom four corners of bottom plate 71 respectively
Portion, the top fixed setting control device 1 and nuclear magnetic resonance spectrometer 3 of lifting platform 72, the top fixed setting of nuclear magnetic resonance spectrometer 3
Magnet system 4, gradient system 5 and radio frequency system 6, the driving device of lifting platform 72 are electrically connected control device 1, and control device 1 is controlled
The lifting of lifting platform 72 processed, it is mobile for convenience, push rod 74 is provided at the top of bottom plate 71.
In the various embodiments described above, it is preferable that as shown in figure 4, movable supporting frame 7 can use arm type bracket, it is especially suitable
It is measured for regular sitting posture, arm type bracket includes two for the mechanical arm fixed with wall, wherein using on a mechanical arm
In fixed setting magnet system 4, gradient system 5 and radio frequency system 6, another mechanical arm is for being fixedly installed 1 He of control device
Nuclear magnetic resonance spectrometer 3.
In the various embodiments described above, it is preferable that magnet system 4 uses existing Halbach structure, in existing Halbach
The size for reducing every piece of magnet in structure basis, arranges according to cramped construction, guarantees weaker outside under the premise of small weight
Magnetic flux leakage, safety in actual instrumentation use process.As shown in figure 5, the magnet system 4 of the utility model includes magnet skeleton disk
41, according to the magnets magnetic fields distribution circuit that simulation calculates, 8 pieces of the annular space inner circumferential interval setting of magnet skeleton disk 41 is small-sized
Passive shimming unit 43 is fixedly installed in permanent magnet blocks 42, the inner ring of magnet skeleton disk 41, and passive shimming unit 43 is used in magnet
The intracavitary distance by slightly adjusting magnet guarantees that the transverse plane uniformity of magnetic field in circle ring chamber reaches higher level.
In the various embodiments described above, it is preferable that as shown in fig. 6, gradient system 5 includes 4 chip units 51, each patch list
51 height axially of member is H1, and the width along diameter circumferential direction is W1, by adjusting each chip unit height,
Width and Inside coil distribution path realize the high-intensitive gradient of cylindrical cavity inner space, can also use existing gradient system
System is realized.Gradient system 5 provided by the utility model can generate the high magnetic field gradients of 0.7 T/m in search coverage, detect
The magnetic field strength generated outside region is less than 3mT, to not influence magnet generation while reaching high-resolution Effect on Detecting
Magnetostatic field.
In the various embodiments described above, it is preferable that radio frequency system 6 is formed spirally using the radio-frequency coil winding mode for becoming spacing
Structure calculates the optimal distance between the optimal the number of turns of helix and circle and circle by using function optimization algorithm, expands radio frequency
The coverage area in magnetic field, increase can imaging domain, while improving the uniformity of RF magnetic field, avoid the generation of image artifacts, this reality
The signal-to-noise ratio that proton (1H) core acquires signal can be promoted to 100 or more with novel offer radio frequency system 6.As shown in fig. 7,
The radio frequency system of the application includes 12 layers of radio-frequency coil around to along between two layers of radio-frequency coil every on cylinder axial direction
It is divided into G, the height of each radio-frequency coil is followed successively by H6, H5, H4, H3, H2, H1, H1, H2, H3, H4, H5, H6 from top to bottom, leads to
Above 7 parameters (H1, H2, H3, H4, H5, H6 and G) of adjustment are crossed, guarantee that the RF magnetic field uniformity in circle ring chamber reaches
Higher level.
In the various embodiments described above, it is preferable that nuclear magnetic resonance spectrometer 3 carries wireless control using light and handy succinct unified platform
Mode is realized, can emit equipment (the mobile phone, plate) completion for receiving wireless signal to nuclear magnetic resonance spectrometer using any
Real-time control changes the fixation operating mode of routine MRI to all tasks of data processing and display.Wherein, nuclear magnetic resonance
The control unit of spectrometer adds one piece of system on chip (SoC) chip and router, realizes that transmitting receives the function of wireless signal,
Built-in microlinux system web server in middle SoC chip, for establishing the network of nuclear magnetic resonance spectrometer 3 Yu control device 1
Communication, control device 1 can be the forms such as plate, desk-top, notebook, realize packaged type acquisition.Control device 1 can pass through nothing
Line emits the control unit that receiving unit 2 connects nuclear magnetic resonance spectrometer, MRI experiment is started or stoped or changes parameter etc.
Operation.
The working principle of the utility model are as follows: after pulse train required for operating is emitted by control device 1, by wireless
Transmitting receiving unit 2 is transmitted in nuclear magnetic resonance spectrometer 3, is generated digital RF and is emitted signal.Signal is generated by internal configuration
Power amplifier amplification after, by tuned cell and matching unit, received by radio frequency system 6.At the same time, digital gradient is believed
It is transmitted in gradient system 5 after number also being generated and amplified by nuclear magnetic resonance spectrometer 3.So far, the radio frequency provided by radio frequency system 6
The gradient magnetic collective effect that the magnetostatic field and gradient coil 5 that magnetic field, magnet system 4 are contributed apply completes core in subject
Magnetic resonance measurement.The NMR signal collected is transmitted in nuclear magnetic resonance spectrometer 3 after being acquired again by radio frequency system 6, is passed through
It is uploaded in control device 1 by the reprinting of wireless transmitter receiver unit 2, is finally completed the transmitting of entire nuclear magnetic resonance data and connects
It receives.
Packaged type magnetic resonance imaging system provided by the utility model can carry out experiment below:
1) nuclear magnetic resonance experiment relevant to relaxation, comprising: pulse experiment, spin echo experiment, more echometric measurements are horizontal
To relaxation time experiment, inversion recovery and saturation recovery measurement longitudinal relaxation time experiment;
2) nuclear magnetic resonance experiment relevant to diffusion, comprising: pulse field gradient spin echo and stimulated echo test, are constant
Field gradient spin echo and stimulated echo experiment;
3) nuclear magnetic resonance experiment relevant to two-dimensional imaging, comprising: frequency coding and phase code imaging experiment, from cycle
Wave imaging and gradient echo imaging experiment.
According to the disclosure and teachings of the above specification, the utility model those skilled in the art can also be to above-mentioned reality
The mode of applying carries out change and modification appropriate.Therefore, the utility model is not limited to specific implementation disclosed and described above
Mode should also be as falling into the protection scope of the claims of the present utility model to some modifications and changes of the utility model.
In addition, although using some specific terms in this specification, these terms are merely for convenience of description, not to this reality
With novel composition any restrictions.
Claims (6)
1. a kind of packaged type magnetic resonance imaging system, which is characterized in that the magnetic resonance imaging system includes control device, wireless
Emit receiving unit, nuclear magnetic resonance spectrometer, radio frequency system, gradient system, magnet system and movable supporting frame;
The control device is for emitting pulse train and being sent to the nuclear magnetic resoance spectrum through the wireless transmitter receiver unit
Instrument;
The nuclear magnetic resonance spectrometer is described for receiving pulse train and generating digital RF transmitting signal and digit gradient signal
Digital RF transmitting signal is sent to the radio frequency system after processing, and the digit gradient signal is sent to gradient after processing
System;
The radio frequency system, gradient system and magnet system collective effect are in the NMR signal being tested, the core
Magnetic resonance signal is transmitted to the nuclear magnetic resonance spectrometer after being acquired by the radio frequency system, while through the wireless transmitter receiver list
Member is uploaded to the control device;
The movable supporting frame is used to support fixed above-mentioned control device, wireless transmitter receiver unit, nuclear magnetic resonance spectrometer, radio frequency
System, gradient system and magnet system realize the movement of the magnetic resonance imaging system.
2. packaged type magnetic resonance imaging system according to claim 1, which is characterized in that the movable supporting frame uses
Liftable type trolley, the Liftable type trolley include bottom plate, lifting platform and idler wheel, the bottom four corners difference of the bottom plate
An idler wheel is fixedly installed, the bottom of the lifting platform is fixedly connected at the top of the bottom plate, the top of the lifting platform is solid
The control device and nuclear magnetic resonance spectrometer are set surely, and magnet system, gradient is fixedly installed in the top of the nuclear magnetic resonance spectrometer
The driving device of system and radio frequency system, the lifting platform is electrically connected the control device, for controlling the liter of the lifting platform
Drop.
3. packaged type magnetic resonance imaging system according to claim 2, which is characterized in that also fixed at the top of the bottom plate
It is provided with push rod.
4. packaged type magnetic resonance imaging system according to claim 1, which is characterized in that the movable supporting frame uses
Arm type bracket, the arm type bracket include two mechanical arms being used for wall fixation, are consolidated on a mechanical arm
The magnet system, gradient system and radio frequency system are set surely, the control device is fixedly installed on another mechanical arm
And nuclear magnetic resonance spectrometer.
5. packaged type magnetic resonance imaging system according to any one of claims 1 to 4, which is characterized in that the magnet
System includes magnet skeleton disk, and eight pieces of permanent magnet blocks, the magnetic is arranged in the annular space inner circumferential interval of the magnet skeleton disk
Passive shimming unit is fixedly installed in the inner ring of body skeleton disk, and the passive shimming unit is used in magnet chamber by adjusting magnet
Distance, guarantee that transverse plane uniformity of magnetic field is horizontal.
6. packaged type magnetic resonance imaging system according to any one of claims 1 to 4, which is characterized in that the radio frequency
System includes 12 layers of radio-frequency coil, is divided into G along between two layers of radio-frequency coil every on cylinder axial direction, each described to penetrate
The height of frequency coil is followed successively by H6, H5, H4, H3, H2, H1, H1, H2, H3, H4, H5, H6 from top to bottom, by adjusting parameter H1,
H2, H3, H4, H5, H6 and G guarantee the intracorporal RF magnetic field uniformity levels of chamber.
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Cited By (2)
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CN113238176A (en) * | 2021-05-19 | 2021-08-10 | 江苏力磁医疗设备有限公司 | Magnetic resonance imaging apparatus and system |
WO2021262726A1 (en) * | 2020-06-22 | 2021-12-30 | Rn Technologies, Llc | Multi-sensor analysis for autonomous systems and devices |
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WO2021262726A1 (en) * | 2020-06-22 | 2021-12-30 | Rn Technologies, Llc | Multi-sensor analysis for autonomous systems and devices |
CN113238176A (en) * | 2021-05-19 | 2021-08-10 | 江苏力磁医疗设备有限公司 | Magnetic resonance imaging apparatus and system |
WO2022241924A1 (en) * | 2021-05-19 | 2022-11-24 | 江苏力磁医疗设备有限公司 | Magnetic resonance imaging device and system |
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