CN205683391U - Medicine delivery capsule - Google Patents
Medicine delivery capsule Download PDFInfo
- Publication number
- CN205683391U CN205683391U CN201620171804.2U CN201620171804U CN205683391U CN 205683391 U CN205683391 U CN 205683391U CN 201620171804 U CN201620171804 U CN 201620171804U CN 205683391 U CN205683391 U CN 205683391U
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- solenoid
- permanent magnet
- circuit
- magnetic
- signal
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- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
A kind of medicine delivery capsule, the dispenser check valve including shell and being set in sequence in shell, the first permanent magnet, medicine storing bag, solenoid, the second permanent magnet, azimuthal measurement and excited magnetic control module, it is provided with photoelectric tube in the periphery of solenoid.First permanent magnet and the second permanent magnet are the most magnetized cylinder permanent magnet, and press magnetic pole opposed, form gradient magnetic.Solenoid is moving type electromagnetic coil, and the excited signal of solenoid is provided with excited magnetic control module by azimuthal measurement.This utility model setting by gradient magnetic, it is to avoid when dispenser dosage is bigger, along with solenoid movement travel increases, the field drives power that solenoid increases away from Magnetic Field Source distance and causes decays rapidly, it is achieved that the release of heavy dose of medicine.
Description
Technical field
This utility model relates to medical supplies, particularly relates to a kind of medicine delivery capsule.
Background technology
Current gastrointestinal tract class chronic disease mostly need drug administration to carry out long-term treatment, but medication effect
The best；Additionally, for focus Hypertrophic in digestive tract, owing to oral drugs are difficult to directly arrive lesions position or arrive focus agent
Measure too small, thus cause the inefficacy of oral drugs therapy.Therefore, if can inflammation, wound surface, affected area directly and efficiently carry out to
Medicine is treated, and the absorption that both can strengthen medicine realizes efficiently treatment, and can reduce side effects of pharmaceutical drugs, thus safety is non-invasively implemented
Target administrations etc. get involved medical care precess.
The Enterion TM pill profile that Phaeton Research (Nottingham, UK) researchs and develops is Φ 1lmm
× 32mm, utilizes high frequency magnetic field to trigger controlling organization, uses scintigraphy (Gamma Scintgraphy) to carry out medicine position
Monitoring, taking dose is 0.8ml, is current application preferable digestive tract medicine location release engineering system pill.The method is being entered
During row medicine position monitoring, measured is caused radiation injury, need main equipment to use inconvenience.S.Murad et al. utilizes shape
Shape memory alloys automatically recovers the characteristic of hence shape under certain condition against the course of processing, it is achieved drug release.The program is not
Can realize release is repeated several times, and releasing dosage is uncontrollable.R.Groening et al. proposes and utilizes gas reaction to produce
Air pressure, as power, promotes piston, completes to spray the action of medicine.Spray medicine action uses high-frequency signal to trigger, and produces sense in capsule
Induced current, the gas of excited gas reative cell starts reaction.The method can realize being repeated several times drug release, but waits after triggering
Time longer, need up to a few hours.Current digestive tract site-specific drug release system, has following weak point: trigger
Time is longer, may cause territory, device for administration of drugs missed target areas；Can be only done single administration action.
Utility model content
The purpose of this utility model, it is simply that in order to provide a kind of medicine delivery capsule, to realize the reliability, quickly of dispenser
Property, the controllability of drug release and repeatedly drug release action.
In order to achieve the above object, this utility model have employed techniques below scheme: a kind of medicine delivery capsule, including outside
Shell and the dispenser check valve being set in sequence in shell, the first permanent magnet, medicine storing bag, solenoid, the second permanent magnet, orientation
Measuring and excited magnetic control module, be provided with photoelectric tube in the periphery of solenoid, wherein, the first permanent magnet is provided with axially extending bore,
Connect with check valve, medicine storing bag respectively before and after this through hole.
Described first permanent magnet and the second permanent magnet are the most magnetized cylinder permanent magnet, and press the contrary cloth of magnetic pole
Put, form gradient magnetic.
Described solenoid is moving type electromagnetic coil, and the excited signal of solenoid is by azimuthal measurement and excited magnetic control mould
Block provides.
The number of described photoelectric tube is arranged according to spraying times, and uniform intervals is arranged in the movement travel of solenoid
Both sides.
Described azimuthal measurement and excited magnetic control module include alternation magnetic signal sensor, alternation magnetic signal signal processing electricity
Road, sampling and A/D convertor circuit, azimuth detection bodies internal circuit, azimuth signal process circuit, microcontroller, exciting circuit,
Internal RF transceiver and antenna；The input that the output of azimuth detection bodies internal circuit processes circuit with azimuth signal is connected,
The output of azimuth signal process circuit, via sampling and A/D convertor circuit, is connected to the input of microcontroller, alternation magnetic signal
The output of sensor is connected with the input of alternation magnetic signal signal processing circuit, the output warp of alternation magnetic signal signal processing circuit
By sampling and A/D convertor circuit, being connected to the input of microcontroller, microcontroller is bi-directionally connected with internal RF transceiver, micro-control
The output of device processed connects the input of exciting circuit, and the input of microcontroller connects photoelectric tube, and the output of exciting circuit connects electricity
Magnetic coil.
Medicine delivery capsule of the present utility model coordinates the external module of azimuth determination, the external module of position measurement, external
RF transceiver and data processing platform (DPP) use: have the advantage that
1, use double magnetic vector detection technique and quaternary number spin theory, the alternation magnetic vector model of benchmark system is converted into
Kinetic coordinate system, decreases the unknown quantity number following the tracks of mathematical model, improves the quick real-time of tracking, improve and ask
Solve precision.
2, dispenser driving means uses the gradient magnetic that two permanent magnets are formed, and places moving type electromagnetic coil wherein,
Actuator as dispenser.The introducing of gradient magnetic, it is to avoid when dispenser dosage is bigger, along with solenoid movement travel increases
Adding, solenoid increases, away from Magnetic Field Source distance, the field drives power caused and decays rapidly, can realize the release of heavy dose of medicine.Light
Electricity is arranged in the movement travel both sides of moving type electromagnetic coil to pipe uniform intervals, is used for realizing repeatedly drug release action.
3, have employed the structure of dispenser check valve, and be provided with suitable unlatching pressure, on the one hand can make at non-dispenser shape
Under state, the medicinal liquid in medicine storing bag will not be revealed；On the other hand, when needs dispenser, the driving acting on medicine storing bag only need to be made
Power, more than the unlatching pressure of check valve, i.e. achieves the function of drug release.Guarantee is provided for repeatedly dispenser.
Accompanying drawing explanation
Fig. 1 is the structural representation of medicine delivery capsule of the present utility model.
Fig. 2 is the composition frame chart of the azimuthal measurement in this utility model and excited magnetic control module.
Detailed description of the invention
Seeing Fig. 1, coordinate and see Fig. 2, medicine delivery capsule of the present utility model, including shell 1 and be set in sequence in
Dispenser check valve the 2, first permanent magnet 3 in shell, medicine storing bag 4, solenoid the 5, second permanent magnet 6, azimuthal measurement are with excitatory
Control module 7, is provided with photoelectric tube 8 in the periphery of solenoid 5, and wherein, the first permanent magnet is provided with axially extending bore, this through hole
Connect with check valve, medicine storing bag the most respectively.
First permanent magnet therein and the second permanent magnet are the most magnetized cylinder permanent magnet, and press the contrary cloth of magnetic pole
Put, form gradient magnetic.Solenoid is moving type electromagnetic coil, and the excited signal of solenoid is by azimuthal measurement and excitatory control
Molding block provides.The number of photoelectric tube is arranged according to spraying times, and uniform intervals is arranged in the movement travel of solenoid
Both sides.
See Fig. 2, the azimuthal measurement in this utility model and excited magnetic control module 7 include alternation magnetic signal sensor 71,
Alternation magnetic signal processes circuit 72, sampling and A/D convertor circuit 73, azimuth detection bodies internal circuit 74, azimuth signal process electricity
Road 75, microcontroller 76, exciting circuit 77, internal RF transceiver 78 and antenna 79；The output of azimuth detection bodies internal circuit
With azimuth signal process circuit input be connected, azimuth signal process circuit output via sample and A/D convertor circuit,
It is connected to the input of microcontroller, the input phase of the output of alternation magnetic signal sensor and alternation magnetic signal signal processing circuit
Even, the output of alternation magnetic signal signal processing circuit, via sampling and A/D convertor circuit, is connected to the input of microcontroller, micro-control
Device processed is bi-directionally connected with internal RF transceiver, and the output of microcontroller connects the input of exciting circuit, the input of microcontroller
Connecting photoelectric tube, the output of exciting circuit connects solenoid.
Medicine delivery capsule of the present utility model coordinates the external module of azimuth determination, the external module of position measurement, external
RF transceiver and data processing platform (DPP) use, and its operation principle is described as follows: azimuth detection uses three axle earth's magnetic field detections
Principle and quaternary number spin theory.First the ground magnetic vector component in the frame of reference is detected by the external module of azimuth determination；
Meanwhile, detection bodies internal circuit detection ground, the azimuth magnetic vector in capsule is at the component of moving coordinate system, at azimuth signal
Reason circuit, sampling and A/D convertor circuit deliver to microprocessor, then by internal RF transceiver, antenna wireless transmission to data at
Platform.According to quaternary number spin theory, data processing platform (DPP) can obtain the rotation quaternary number being tied to moving coordinate system by benchmark.
Subsequently, excitatory to four Magnetic Field Source by position measurement external module timesharing, it is sequentially generated alternating magnetic field.By in capsule
Alternation magnetic signal sensor magnetic signal is converted to the signal of telecommunication, via alternation magnetic signal process circuit, sampling and AD conversion electricity
Microcontroller is delivered on road, then by internal RF transceiver and antenna wireless transmission to the most external RF transceiver, external penetrates
Frequently transceiver transfers data to data processing platform (DPP) and processes in real time.Data processing platform (DPP) is according to the rotation quaternary obtained
Number, by the kinetic coordinate system rotation transformation of medicine delivery capsule to the external frame of reference, sets up space magnetic vector and capsule
The mathematical model of position, solves it, it is thus achieved that the position of capsule, it is achieved the position of medicine delivery capsule is followed the tracks of.Pending data processes
Platform calculates capsule position and has been enter into dispenser target area, and data processing platform (DPP) sends dispenser via external radio-frequency transceiver and touches
Signaling, internal RF transceiver receives this signal by antenna, transmits the microcontroller to medicine delivery capsule.So
After, microcontroller outputs signal to exciting circuit, makes solenoid energization excitation.By solenoid magnetic in gradient magnetic
Field force, as dispenser power source, extrudes medicine storing bag, makes the drug storage intraluminal pressure unlatching pressure more than dispenser check valve, it is achieved medicine
Release.
Photoelectric tube is made up of light-sensitive element and light emitting diode.When the movement travel of solenoid reaches photoelectric tube
During installation site, solenoid is no longer between photoelectric tube, and therefore, the light-sensitive element of photoelectric tube can receive luminous two
The light that pole pipe sends, the output signal of light-sensitive element changes.Microcontroller in capsule reads the output of photoelectric tube
After the change of signal, microcontroller output signal controls exciting circuit, makes solenoid power-off, stops the release of medicine.
Pending data processing platform calculates capsule position when having been enter into next dispenser target area, data processing platform (DPP) warp
Sent dispenser by external radio-frequency transceiver and trigger signal, trigger the drug release of a new round, until moving type electromagnetic coil movement
Installation site to next photoelectric tube.Thus, repeatedly drug release action can be realized.
Claims (3)
1. a medicine delivery capsule, it is characterised in that: include shell and the dispenser check valve being set in sequence in shell,
One permanent magnet, medicine storing bag, solenoid, the second permanent magnet, azimuthal measurement and excited magnetic control module, set in the periphery of solenoid
Having photoelectric tube, wherein, the first permanent magnet is provided with axially extending bore, connects with check valve, medicine storing bag respectively before and after this through hole；
Described first permanent magnet and the second permanent magnet are the most magnetized cylinder permanent magnet, and press magnetic pole opposed, shape
Become gradient magnetic；
Described azimuthal measurement and excited magnetic control module include alternation magnetic signal sensor, alternation magnetic signal signal processing circuit, adopt
Sample and A/D convertor circuit, azimuth detection bodies internal circuit, azimuth signal process circuit, microcontroller, exciting circuit, internal penetrate
Frequently transceiver and antenna；The input that the output of azimuth detection bodies internal circuit processes circuit with azimuth signal is connected, azimuth
The output of signal processing circuit, via sampling and A/D convertor circuit, is connected to the input of microcontroller, alternation magnetic signal sensor
Output be connected with the input of alternation magnetic signal signal processing circuit, the output of alternation magnetic signal signal processing circuit is via sampling
And A/D convertor circuit, it being connected to the input of microcontroller, microcontroller is bi-directionally connected with internal RF transceiver, microcontroller
Output connects the input of exciting circuit, and the input of microcontroller connects photoelectric tube, and the output of exciting circuit connects solenoid.
2. medicine delivery capsule as claimed in claim 1, it is characterised in that: described solenoid is moving type electromagnetic coil,
The excited signal of solenoid is provided with excited magnetic control module by azimuthal measurement.
3. medicine delivery capsule as claimed in claim 1, it is characterised in that: the number of described photoelectric tube is according to spraying times
Arrange, and uniform intervals is arranged in the movement travel both sides of solenoid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620171804.2U CN205683391U (en) | 2016-03-07 | 2016-03-07 | Medicine delivery capsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620171804.2U CN205683391U (en) | 2016-03-07 | 2016-03-07 | Medicine delivery capsule |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205683391U true CN205683391U (en) | 2016-11-16 |
Family
ID=57264553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620171804.2U Expired - Fee Related CN205683391U (en) | 2016-03-07 | 2016-03-07 | Medicine delivery capsule |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205683391U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107158552A (en) * | 2016-03-07 | 2017-09-15 | 上海理工大学 | Drug delivery capsule and medicament delivery method |
| CN115089807A (en) * | 2022-06-22 | 2022-09-23 | 上海力声特医学科技有限公司 | Implantable drug delivery system |
-
2016
- 2016-03-07 CN CN201620171804.2U patent/CN205683391U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107158552A (en) * | 2016-03-07 | 2017-09-15 | 上海理工大学 | Drug delivery capsule and medicament delivery method |
| CN107158552B (en) * | 2016-03-07 | 2020-09-08 | 上海理工大学 | Drug delivery capsule and drug delivery method |
| CN115089807A (en) * | 2022-06-22 | 2022-09-23 | 上海力声特医学科技有限公司 | Implantable drug delivery system |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20161116 Termination date: 20190307 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |