CN203873762U - No-injury blood glucose detector based on blood raman scattering of blood vessels of eyes - Google Patents
No-injury blood glucose detector based on blood raman scattering of blood vessels of eyes Download PDFInfo
- Publication number
- CN203873762U CN203873762U CN201420277101.9U CN201420277101U CN203873762U CN 203873762 U CN203873762 U CN 203873762U CN 201420277101 U CN201420277101 U CN 201420277101U CN 203873762 U CN203873762 U CN 203873762U
- Authority
- CN
- China
- Prior art keywords
- blood
- blood vessel
- module
- raman scattering
- laser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn - After Issue
Links
Landscapes
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The utility model provides a no-injury blood glucose detector based on blood raman scattering of the blood vessels of the eyes. The no-injury blood glucose detector comprises a module for seeking the blood vessels, a laser focus projection module and a signal detecting and analyzing module, wherein the module for seeking the blood vessels, the laser focus projection module and the signal detecting and analyzing module are sequentially connected. The module for seeking the blood vessels is used for seeking and selecting the blood vessels on the surfaces of the conjunctivae or the sclera and locating coordinates of the blood vessels. The laser focus projection module is used for projecting the laser focus to the blood in the selected blood vessels according to the located coordinates of the blood vessels. The signal detecting and analyzing module is used for collecting scattered light generated by the blood in the blood vessels selected by laser radiation, analyzing the blood glucose level according to the raman scattering spectrum analysis of the detected scattered light, and displaying the blood glucose level. According to the no-injury blood glucose detector based on blood raman scattering of the blood vessels of the eyes, the blood does not need to be sampled from a patient, consumable items like test paper are not needed either, and the blood glucose can be directly detected and displayed automatically, intelligently and fast in real time under the circumstance of not injuring the human body; moreover, detecting can be repeatedly carried out many times according to needs, which is beneficial for monitoring the blood glucose.
Description
Technical field
This utility model relates to a kind of blood-sugar detecting instrument, particularly relates to a kind of harmless blood sugar test based on the Raman scattering of eye blood vessel.
Background technology
Blood sugar test is exactly making regular check on blood glucose value.Implement blood sugar test and can grasp better the change of blood sugar of human body.This is for people, and especially rule of life, motion, diet and the rational use of drug for diabetics has important directive significance, and can help diabetics to pinpoint the problems in time, to reduce the risk of diabetic complication.Meanwhile, the result of blood sugar test is used to reflect the result of diet control, exercise therapy and Drug therapy, thereby can adjust therapeutic scheme.
Blood sugar test of the prior art mainly comprises following several mode:
(1) directly from human body, extract certain blood volume, utilize in vitro the method for biology or physics to detect the concentration of glucose in blood.Yet, no matter take any method to get blood, be all that human body is being damaged in situation and carried out, can bring certain damage and mental burden to detected person, and have the risk of infection.
(2) light is arrived to veins beneath the skin or blood capillary etc. through skin exposure, by measuring absorbing light or scattered light, judge the concentration of glucose in blood.Yet, although the method reaches the object of Non-Destructive Testing blood glucose, because the thickness of the skin of different people, subcutaneous fat, muscle etc. is different, and different to the absorbability of light, cause the deviation of blood sugar test larger.
(3) by measuring outer other tissue of saliva, expiration or blood of human body etc. of people, reach the Non-Destructive Testing of blood glucose.Although saliva or expiration or other tissue etc. may there is certain functional relationship with blood glucose value about a minute subconstiuent, time have difference on mutually, and the functional relationship of Different Individual with time facial difference also very not identical, therefore detection error is larger.Therefore, up to the present the method still fails to be actually used in clinical use.
Research shows, it is exposed on surface on the conjunctiva of human body eye and sclera, having quite a lot of blood vessels.So light can shine directly on the blood of these blood vessels, just can avoid thus the absorption of the each several parts such as skin, subcutaneous fat, muscle to disturb, thereby obtain directly, in real time the blood sugar content in blood.Therefore the Non-Destructive Testing of, carrying out blood glucose by conjunctiva or sclera blood vessel becomes an extremely promising research topic.
Utility model content
The shortcoming of prior art in view of the above, the purpose of this utility model is to provide a kind of harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, it is radiated at low power laser in the blood of conjunctiva or sclera blood vessel, and the scattered light producing by determination and analysis laser irradiation vessel inner blood reaches the real non-destructive of blood glucose is detected.
For achieving the above object and other relevant objects, this utility model provides a kind of harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, comprises the target-seeking module of connected successively blood vessel, laser focusing projection module and signal detection analysis module; The target-seeking module of described blood vessel for find and selected conjunctiva or scleral surface on blood vessel, and localization of blood vessel coordinate; Described laser focusing projection module is for projecting laser focusing the blood of selected blood vessel according to located blood vessel coordinate; The scattered light that described signal detection analysis module produces for gathering the blood of the selected blood vessel of laser irradiation, and according to the Raman diffused light analysis of spectrum of the scattered light detecting and demonstrate blood glucose value.
According to the above-mentioned harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, wherein: the target-seeking module of described blood vessel, described laser focusing projection module and described signal detection analysis module are all placed in casing, described casing one end has a detection window, and described detection window is aimed at eyeball when detecting.
Further, according to the above-mentioned harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, wherein: in described detection window, with cover film, shelves are lived external stray light when detecting.
According to the above-mentioned harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, wherein: the target-seeking module of described blood vessel comprises eyeball guiding lamp, illuminating lamp, photographic head and blood vessel identification and locating module;
Described eyeball guiding lamp is for guiding the eyeball of user draw close and conjunctiva and sclera are exposed to nasal side;
Described illuminating lamp is for throwing light on to the blood vessel of conjunctiva and sclera;
Described photographic head is for taking the blood-vessel image of conjunctiva and sclera;
The identification of described blood vessel and locating module are a certainly positioned at the blood vessel of conjunctiva or sclera and locate its coordinate for selecting according to the size of captured each blood vessel of blood-vessel image and color.
According to the above-mentioned harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, wherein: described laser focusing projection module comprises laser instrument, two scanning galvanometers and scanning galvanometer driver; Described scanning galvanometer driver, for after receiving the coordinate information of selected blood vessel, drives described two scanning galvanometers, and the laser focusing that described laser instrument is launched projects on selected blood vessel.
Further, according to the above-mentioned harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, wherein: described laser instrument adopts semiconductor laser, and launching wavelength is 785nm, the semiconductor infrared line laser that output is 1-5mW; Described scanning galvanometer adopts reflective scanning mode galvanometer.
According to the above-mentioned harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, wherein: described signal detection analysis module comprises reflect focalization mirror, condenser lens, light filter, Raman spectrometer and analysis display module;
The scattered light that described reflect focalization mirror produces for reflecting the blood of laser irradiation blood vessel;
Described condenser lens is for the scattered light of focus reflection focus lamp reflection;
Incident illumination or other veiling glare filtering that described light filter may be mingled with for the light that condenser lens focusing is come;
Described Raman spectrometer is for detection of the raman scattering spectrum of the scattered light after focusing on;
Described analysis display module is used for according to the testing result of described Raman spectrometer, the ratio at the spectrum peak of corresponding blood glucose and spectrum peak corresponding to haemachrome in Raman diffused light relatively, thereby according to above-mentioned two the spectrum ratios at peak and the calibration curve of blood glucose relation that obtain in advance, determine blood glucose value, and it is shown on display screen.
Further, according to the above-mentioned harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, wherein: described light filter is only greater than the light of lambda1-wavelength by wavelength.
As mentioned above, harmless blood-sugar detecting instrument and the detection method based on the Raman scattering of eye blood vessel of the present utility model, has following beneficial effect:
(1) need not get blood to patient, under to human body lossless case, blood glucose be carried out directly, detected in real time;
(2) owing to being by laser being directly radiated to the blood vessel of conjunctiva or scleral surface to the detection of blood glucose, and realize from the scattered light acquisition blood sugar content of its blood, therefore can get rid of the absorption of skin, subcutaneous fat and muscle etc., disturb, make blood sugar test result accurately reliable;
(3) testing process automatic quick, and the low power laser irradiating is harmless, can not cause the temperature rise that surpasses 0.5 ° of C, and user can complete detection in the situation that not having any discomfort;
(4) owing to being nondestructive measurement, can repeatedly repeatedly carry out as required blood sugar test, be more conducive to the monitoring to blood glucose;
(5) compact conformation, easy to use, and do not need other consumptive materials such as reagent paper, can directly show blood glucose value.
Accompanying drawing explanation
Fig. 1 is shown as the structural representation of the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel of the present utility model;
Fig. 2 is shown as the working state schematic representation of the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel of the present utility model;
Fig. 3 is shown as the flow chart of the harmless blood sugar detecting method based on the Raman scattering of eye blood vessel of the present utility model.
Element numbers explanation
The target-seeking module of 1 blood vessel
11 eyeball guiding lamps
12 illuminating lamps
13 photographic head
14 blood vessel identification and locating modules
2 laser focusing projection module
21 laser instrument
22 scanning galvanometer drivers
23 two scanning galvanometers
3 signal detection analysis modules
31 reflect focalization mirrors
32 condenser lenses
33 light filters
34 Raman spectrometers
34 analyze display module
4 blood vessels
The specific embodiment
By specific instantiation, embodiment of the present utility model is described below, those skilled in the art can understand other advantages of the present utility model and effect easily by the disclosed content of this description.This utility model can also be implemented or be applied by the other different specific embodiment, and the every details in this description also can be based on different viewpoints and application, carries out various modifications or change not deviating under spirit of the present utility model.
It should be noted that, the diagram providing in the present embodiment only illustrates basic conception of the present utility model in a schematic way, satisfy and only show with assembly relevant in this utility model in graphic but not component count, shape and size drafting while implementing according to reality, during its actual enforcement, kenel, quantity and the ratio of each assembly can be a kind of random change, and its assembly layout kenel also may be more complicated.
With reference to Fig. 1, the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel of the present utility model comprises the target-seeking module 1 of connected successively blood vessel, laser focusing projection module 2 and signal detection analysis module 3.Wherein, the target-seeking module 1 of blood vessel for find and selected conjunctiva or scleral surface on blood vessel, and localization of blood vessel coordinate; Laser focusing projection module 2 is for projecting laser focusing the blood of selected blood vessel according to located blood vessel coordinate; The scattered light that signal detection analysis module 3 produces for gathering the blood of the selected blood vessel of laser irradiation, and according to the Raman diffused light analysis of spectrum of the scattered light detecting and demonstrate blood glucose value.
In a preferred embodiment of the present utility model, the target-seeking module 1 of blood vessel, laser focusing projection module 2 and signal detection analysis module 3 are encapsulated in handheld portable casing.Casing one end has a detection window, and detection window is slightly larger and with soft cover film than human eye, to can aim at eyeball and shelves are lived external stray light when detecting.
Particularly, the target-seeking module 1 of blood vessel comprises eyeball guiding lamp 11, illuminating lamp 12, photographic head 13 and blood vessel identification and locating module 14.
Wherein, eyeball guiding lamp 11 is for guiding the eyeball of user draw close and conjunctiva and sclera are exposed to nasal side.Particularly, eyeball guiding lamp 11 is arranged in detection window.During detection, eyeball guiding lamp 11 sends the low-light flashing near nasal side at eyes, to guide the eyeball of user to turn to nasal side, thereby expose conjunctiva and sclera.
Illuminating lamp 12 is for the blood vessel of conjunctiva and sclera is thrown light on, so that photographic head photographic images clearly.Preferably, illuminating lamp can adopt LED lamp, and it is by sending diffusion sheen, and conjunctiva and sclera blood vessel throw light on.
Photographic head 13, for taking the blood-vessel image of conjunctiva and sclera, adopts colored digital photographic head conventionally.
Blood vessel identification and locating module 14 be for according to the selected a certain blood vessel of the color of captured each blood vessel of blood-vessel image and size and locate its coordinate, and coordinate information is sent to laser focusing projection module 2.Wherein, the standard of selected blood vessel is: select the scarlet and the thickest blood vessel of color.
Laser focusing projection module 2 comprises laser instrument 21, two scanning galvanometers 23 and scanning galvanometer drivers 22.
Wherein, laser instrument 21 is for Emission Lasers.Preferably, can adopt semiconductor laser.
Scanning galvanometer driver 22 is for driven sweep galvanometer.
Two scanning galvanometers 23 project selected blood vessel in the x and y direction for the laser that laser instrument 21 is launched.
When reality is used, after the blood vessel coordinate information of scanning galvanometer driver after receiving location, drive two scanning galvanometers, the laser focusing that laser instrument is launched is projected on selected blood vessel.Preferably, in this utility model, adopting wavelength is 785nm, the semiconductor infrared line laser that output is 1-5mW.Scanning galvanometer adopts reflective scanning mode galvanometer.
Signal detection analysis module 3 comprises reflect focalization mirror 31, condenser lens 32, light filter 33, Raman spectrometer 34 and analyzes display module 35.
The scattered light that reflect focalization mirror 31 produces for reflecting laser irradiation blood vessel blood.
Condenser lens 32 is for the scattered light of focus reflection focus lamp reflection.
Incident illumination or other veiling glare filtering that light filter 33 may be mingled with for the light that condenser lens focusing is come, and only allow scattered light enter Raman spectrometer.Particularly, 33 light that allow wavelength be greater than lambda1-wavelength of light filter pass through, and filter out all other light.
Raman spectrometer 34 is for detection of the raman scattering spectrum of the scattered light after focusing on.
Analyze display module 35 for according to the testing result of Raman spectrometer 34, the ratio at the spectrum peak of corresponding blood glucose and spectrum peak corresponding to haemachrome in Raman diffused light relatively, thereby according to above-mentioned two the spectrum ratios at peak and the calibration curve of blood glucose relation that obtain in advance, determine blood glucose value, and it is shown on display screen.
In a preferred embodiment of the present utility model, on reflect focalization mirror, be provided with three apertures, be respectively used to guide by eyeball the light that lamp, illuminating lamp and photographic head and scanning galvanometer send or receive.
With reference to Fig. 2 and Fig. 3, the harmless blood sugar detecting method based on the Raman scattering of eye blood vessel of the present utility model comprises the following steps:
Step S1, eyeball guiding lamp is luminous near nasal side at eyes, thereby to guide the eyeball of user to turn to nasal side to expose conjunctiva and sclera.
Particularly, by after eyeball aim detecting window, the eyeball of the light guiding user that eyeball guiding lamp 11 sends is drawn close conjunctiva and sclera is exposed to nasal side.Wherein, detection window is slightly larger and with soft cover film than human eye, to can aim at eyeball and shelves are lived external stray light when detecting.
Step S2, under illuminating lamp 12 illumination, photographic head 13 is taken the image of the blood vessel 4 of conjunctiva and sclera, blood vessel identification is selected a certain blood vessel and locates its coordinate according to the color of each blood vessel in image and size with locating module 14, and coordinate information is sent to laser focusing projection module 2.
Wherein, illuminating lamp sends diffusion sheen, for conjunctiva and the sclera blood vessel of throwing light on.Blood vessel identification according to the color of each blood vessel in conjunctiva and sclera image and size, is selected the scarlet and the thickest blood vessel of color with locating module from blood-vessel image in the blood vessel showing, and determines its two-dimensional coordinate.The standard of selected blood vessel is: select the scarlet and the thickest blood vessel of color.
Step S3, scanning galvanometer driver 22 receive after the coordinate information of blood vessel, control two scanning galvanometers 23 laser focusing is projected on this blood vessel.
Particularly, blood vessel identification start laser instrument with locating module and by driving a pair of scanning galvanometer to press located rotation of the coordinate system, the laser-bounce that laser instrument is sent is to selected blood vessel after determining blood vessel coordinate.
The scattered light producing after blood in step S4, the selected blood vessel of reflect focalization device 31 reflection laser irradiation, the scattered light that condenser lens 32 carrys out reflection focuses in light filter 33.
After the incident illumination that may be mingled with in the light that step S5, light filter 33 are come focusing or other veiling glare filtering, send into Raman spectrometer 34.
Particularly, the light that light filter only allows wavelength be greater than lambda1-wavelength enters Raman spectrometer, and filters out all other light.
Step S6, Raman spectrometer 34 detect the raman scattering spectrum of scattered light.
Step S7, analyze the ratio that display module 35 is analyzed the spectrum peak of corresponding blood glucose in Raman diffused lights relatively and spectrum peak corresponding to haemachrome, according to the two spectrum p-ratios that obtain in advance and the calibration curve of blood glucose relation, determine blood glucose value again, and it is shown on display screen, complete blood sugar test task.
In sum, the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel of the present utility model need not be got blood to patient, does not also need the consumptive materials such as any reagent paper, and automated intelligent carries out directly accurately detecting in real time and showing to blood glucose fast under to human body lossless case; Owing to detecting harmless and not having uncomfortable sensation, therefore user can repeatedly carry out on demand repeatedly, be more conducive to the monitoring to blood glucose, control the development of the state of an illness.So this utility model has effectively overcome various shortcoming of the prior art and tool high industrial utilization.
Above-described embodiment is illustrative principle of the present utility model and effect thereof only, but not for limiting this utility model.Any person skilled in the art scholar all can, under spirit of the present utility model and category, modify or change above-described embodiment.Therefore, have in technical field under such as and conventionally know that the knowledgeable modifies or changes not departing from all equivalences that complete under spirit that this utility model discloses and technological thought, must be contained by claim of the present utility model.
Claims (8)
1. the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel, is characterized in that: comprise the target-seeking module of connected successively blood vessel, laser focusing projection module and signal detection analysis module;
The target-seeking module of described blood vessel for find and selected conjunctiva or scleral surface on blood vessel, and localization of blood vessel coordinate;
Described laser focusing projection module is for projecting laser focusing the blood of selected blood vessel according to located blood vessel coordinate;
The scattered light that described signal detection analysis module produces for gathering the blood of the selected blood vessel of laser irradiation, and according to the Raman diffused light analysis of spectrum of the scattered light detecting and demonstrate blood glucose value.
2. the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel according to claim 1, it is characterized in that: the target-seeking module of described blood vessel, described laser focusing projection module and described signal detection analysis module are all placed in casing, described casing one end has a detection window, and described detection window is aimed at eyeball when detecting.
3. the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel according to claim 2, is characterized in that: in described detection window, with cover film, shelves are lived external stray light when detecting.
4. the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel according to claim 1, is characterized in that: the target-seeking module of described blood vessel comprises eyeball guiding lamp, illuminating lamp, photographic head and blood vessel identification and locating module;
Described eyeball guiding lamp is for guiding the eyeball of user draw close and conjunctiva and sclera are exposed to nasal side;
Described illuminating lamp is for throwing light on to the blood vessel of conjunctiva and sclera;
Described photographic head is for taking the blood-vessel image of conjunctiva and sclera;
The identification of described blood vessel and locating module are a certainly positioned at the blood vessel of conjunctiva or sclera and locate its coordinate for selecting according to the size of captured each blood vessel of blood-vessel image and color.
5. the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel according to claim 1, is characterized in that: described laser focusing projection module comprises laser instrument, two scanning galvanometers and scanning galvanometer driver; Described scanning galvanometer driver, for after receiving the coordinate information of selected blood vessel, drives described two scanning galvanometers, and the laser focusing that described laser instrument is launched projects on selected blood vessel.
6. the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel according to claim 5, is characterized in that: described laser instrument adopts semiconductor laser, and launching wavelength is 785nm, the semiconductor infrared line laser that output is 1-5mW; Described scanning galvanometer adopts reflective scanning mode galvanometer.
7. the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel according to claim 1, is characterized in that: described signal detection analysis module comprises reflect focalization mirror, condenser lens, light filter, Raman spectrometer and analysis display module;
The scattered light that described reflect focalization mirror produces for reflecting the blood of laser irradiation blood vessel;
Described condenser lens is for the scattered light of focus reflection focus lamp reflection;
Incident illumination or other veiling glare filtering that described light filter may be mingled with for the light that condenser lens focusing is come;
Described Raman spectrometer is for detection of the raman scattering spectrum of the scattered light after focusing on;
Described analysis display module is used for according to the testing result of described Raman spectrometer, the ratio at the spectrum peak of corresponding blood glucose and spectrum peak corresponding to haemachrome in Raman diffused light relatively, thereby according to above-mentioned two the spectrum ratios at peak and the calibration curve of blood glucose relation that obtain in advance, determine blood glucose value, and it is shown on display screen.
8. the harmless blood-sugar detecting instrument based on the Raman scattering of eye blood vessel according to claim 7, is characterized in that: described light filter is for being only greater than the light of lambda1-wavelength by wavelength.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420277101.9U CN203873762U (en) | 2014-05-27 | 2014-05-27 | No-injury blood glucose detector based on blood raman scattering of blood vessels of eyes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420277101.9U CN203873762U (en) | 2014-05-27 | 2014-05-27 | No-injury blood glucose detector based on blood raman scattering of blood vessels of eyes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203873762U true CN203873762U (en) | 2014-10-15 |
Family
ID=51674324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420277101.9U Withdrawn - After Issue CN203873762U (en) | 2014-05-27 | 2014-05-27 | No-injury blood glucose detector based on blood raman scattering of blood vessels of eyes |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203873762U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105266822A (en) * | 2014-05-27 | 2016-01-27 | 普林斯顿医疗科技（珠海）有限公司 | No-injury blood glucose detector based on blood raman scattering of blood vessels of eyes and detection method |
| WO2016157156A1 (en) * | 2015-04-02 | 2016-10-06 | Livspek Medical Technologies Inc. | Method and apparatus for a spectral detector for noninvasive detection and monitoring of a variety of biomarkers and other blood constituents in the conjunctiva |
| CN107255657A (en) * | 2017-06-07 | 2017-10-17 | 苏州大学 | A kind of chaos decoding method of blood glucose Non-Destructive Testing |
| CN111562714A (en) * | 2020-05-22 | 2020-08-21 | 复旦大学 | Multispectral modulation imaging device based on multi-wavelength LED light source |
-
2014
- 2014-05-27 CN CN201420277101.9U patent/CN203873762U/en not_active Withdrawn - After Issue
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105266822A (en) * | 2014-05-27 | 2016-01-27 | 普林斯顿医疗科技（珠海）有限公司 | No-injury blood glucose detector based on blood raman scattering of blood vessels of eyes and detection method |
| WO2016157156A1 (en) * | 2015-04-02 | 2016-10-06 | Livspek Medical Technologies Inc. | Method and apparatus for a spectral detector for noninvasive detection and monitoring of a variety of biomarkers and other blood constituents in the conjunctiva |
| US9924895B2 (en) | 2015-04-02 | 2018-03-27 | Livspek Medical Technologies Inc. | Method and apparatus for a spectral detector for noninvasive detection and monitoring of a variety of biomarkers and other blood constituents in the conjunctiva |
| CN107255657A (en) * | 2017-06-07 | 2017-10-17 | 苏州大学 | A kind of chaos decoding method of blood glucose Non-Destructive Testing |
| CN111562714A (en) * | 2020-05-22 | 2020-08-21 | 复旦大学 | Multispectral modulation imaging device based on multi-wavelength LED light source |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20210192850A1 (en) | Augmented reality devices for hazardous contaminant testing | |
| CN106580244A (en) | Portable infrared eccentric photorefraction system | |
| CN103188993B (en) | The apparatus and method of the disease of Noninvasive detection influence mechanics of biological tissue property | |
| CN203873762U (en) | No-injury blood glucose detector based on blood raman scattering of blood vessels of eyes | |
| US20020072658A1 (en) | Non-invasive measurement of blood components using retinal imaging | |
| CN106943117A (en) | Biometric information measuring device | |
| CN101190120A (en) | Binocular pupil detecting system | |
| CN102920441A (en) | Collecting and displaying device for hand vein images | |
| CN103096794B (en) | Blood collection device | |
| CN107270818A (en) | It is a kind of to utilize the method for monitoring CCD the real time measures laser probe and plane of illumination spacing walk-off angle degree | |
| CN106510616B (en) | The full-automatic detector of xerophthalmia | |
| CN107397534A (en) | A kind of integrated vein blood vessel identifying system and method | |
| CN109247910B (en) | Blood vessel display device and blood vessel display method | |
| WO2023092753A1 (en) | Vision training apparatus and vision training instrument | |
| CN105266822B (en) | Lossless blood-sugar detecting instrument based on Ocular Vessels blood Raman scattering and detection method | |
| JPWO2014181744A1 (en) | Fluorescence measuring apparatus and fluorescence measuring method | |
| CN110621981A (en) | Non-invasive optical sensor for analyzing substance level in subject by irradiating sclera | |
| CN209285467U (en) | A kind of eyesight detection device based on eccentricity cycles principle | |
| CN1461198A (en) | Ophthalmic device | |
| CN211432840U (en) | Eyepiece formula pupil light reflex automated inspection equipment | |
| CN107961445A (en) | Skin icterus tester | |
| JP2014079374A (en) | Pupil diameter measurement support apparatus and pupil diameter measurement support system | |
| CN201888807U (en) | Portable quick screening and analyzing instrument for glaucoma | |
| CN203591264U (en) | Noninvasive hemoglobin tester | |
| CN208464988U (en) | Skin icterus tester |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20141015 Effective date of abandoning: 20180824 |
|
| AV01 | Patent right actively abandoned |