CN203732539U - Portable immunochromatography analyzer - Google Patents
Portable immunochromatography analyzer Download PDFInfo
- Publication number
- CN203732539U CN203732539U CN201420092120.4U CN201420092120U CN203732539U CN 203732539 U CN203732539 U CN 203732539U CN 201420092120 U CN201420092120 U CN 201420092120U CN 203732539 U CN203732539 U CN 203732539U
- Authority
- CN
- China
- Prior art keywords
- test card
- portable
- reflective mirror
- stationary installation
- light source
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn - After Issue
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/8483—Investigating reagent band
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The utility model relates to the technical field of immune diagnosis instruments, in particular to a portable immunochromatography analyzer. The portable immunochromatography analyzer comprises a test card fixing device, a large reflective mirror used for reflecting a test area, a small reflective mirror used for reflecting a test area image formed in the large reflective mirror as well as an imaging sensor used for capturing a test area image reflected in the small reflective mirror. According to the portable immunochromatography analyzer, under the condition that a direct distance between the imaging sensor and a test card is 2-6 cm, the imaging sensor can acquire effective image information of the whole test area finally through two-time mirror reflection, the thickness of the whole analyzer is reduced, and the characteristic of portability in POCT (point of care testing) is reflected; and moreover, an LED light source group is arranged in an analyzer casing, so that light emitted from the analyzer can be uniformly distributed on the test card loaded in the fixing device, and the imaging sensor can quickly capture effective images of the test area.
Description
Technical field
The utility model relates to immunodiagnosis Instrument technology field, especially relates to a kind of portable immunochromatographiassays assays instrument.
Background technology
Immune chromatograph testing card detection technique is widely used in the every field of POCT fast detecting, and reagent to be detected is collaurum, latex, immunofluorescent reagent etc., and image or color after detecting by picked-up collected specimens when detection are obtained sample detection information.Sample to be tested is extensive, can be human or animal's body fluid, and as blood, urine etc., also can be cell or tissue sample.Its feature is a certain district band that specific antibody is fixed on to chromatography card nitrocellulose membrane, Dang Gai district band is encountered after response sample (urine, or serum), antibody generation specific bond, this region shows certain color, the depth of color and the proportional relation of the concentration of tested sample.By image acquisition device, as CCD, the photosensitive-members such as CMOS, obtain the colour developing information of chromatography strip, by the colour developing result of image processing and analyzing image, thereby obtain quantitative testing result.
The main standard of POCT is not need the detection place fixed, and reagent and instrument are of portable form, and can operate in time.
Existing colloidal gold chromatographic analyser, golden scalar quantity instrument, crossing current immunochromatography instrument etc., be all based on desktop, and structure is larger, does not possess hand-portable.Its main cause is CCD, the photosensitive-members such as CMOS cannot obtain the image of complete surveyed area in short-range focusing range, must ensure to have between surveyed area enough focusings from, this distance is generally larger, as accomplished to obtain in short-range focusing range the image of complete surveyed area, need the CCD of the high-end costliness of buying, CMOS photo-sensitive cell, as wide-angle photo-sensitive cell, greatly increase the manufacturing cost of traditional instrument.
Utility model content
The technical problems to be solved in the utility model is: the image that cannot obtain complete surveyed area in order to overcome photosensitive-member common in prior art in short-range focusing range, apparatus structure is larger, problem that can not hand-portable, a kind of portable immunochromatographiassays assays instrument is provided, by twice mirror-reflection, the direct range of imaging sensor and test card is at 2-6cm, final imaging sensor can obtain the effective image information of whole surveyed area, the thickness of whole instrument is reduced, really embodied the feature of the hand-portable of POCT detection.
The utility model solves the technical scheme that its technical matters adopts: a kind of portable immunochromatographiassays assays instrument, comprising:
Test card stationary installation, described test card stationary installation is provided with surveyed area;
Large reflective mirror, for reflecting the image of described test card stationary installation surveyed area;
Little reflective mirror, for reflecting the image of the described surveyed area that large reflective mirror becomes;
Imaging sensor, for catching the image of the described surveyed area that little reflective mirror reflects.
Test card stationary installation is fixed the position of test card like this, large reflective mirror is arranged on the top of test card, its minute surface and test card are oppositely arranged, large reflective mirror minute surface becomes the angle of 15-30 ° with test card place plane, the minute surface of little reflective mirror arranges in opposite directions with the minute surface of large reflective mirror, little reflective mirror minute surface becomes the angle of 30-45 ° with test card place plane, the image of whole surveyed area is successively through the reflex of excessive reflective mirror and little reflective mirror, final imaging sensor can capture complete, the effectively image of surveyed area, its image-forming principle is as shown in the reflected ray at test card two ends in Fig. 1, by such principle, realized direct range in imaging sensor and test card less, final imaging sensor can obtain effective test card image information of whole surveyed area, reach the object of the thickness that reduces whole instrument.
Image for ease of imaging sensor Quick Catch to effective test card, is also provided with LED light source group in described analyser housing, and its luminous energy sending is evenly distributed in the surveyed area in described test card stationary installation.
Further, described LED light source group comprises LED light source battery, LED light source control line plate and LED lamp, and LED light source battery is by LED light source control line plate control LED lamp, and described LED lamp is fixedly installed between test card stationary installation and large reflective mirror.
Further, for the light that LED lamp sends is evenly distributed in surveyed area and test card more, described LED lamp is fixed with the astigmatic bar of the light uniformization for LED lamp is sent outward.
Particularly, described imaging sensor adopts COMS or ccd imaging sensor.
Particularly, described imaging sensor is can imaging mobile phone, first, the imaging mobile phone is here as long as meet the imaging of can focusing, next is that mobile phone is thinner, can make the thickness of whole instrument further reduce, and has really embodied the feature of the hand-portable of POCT detection; Finally, on the basis of mobile phone, can utilize interior of mobile phone system, corresponding software is installed, analyzing and processing image, makes whole instrument small and exquisite, hand-held, has greatly reduced the high problem of cost of traditional instrument.
Described test card stationary installation pull is loaded and unloaded on takes formula immunity chromatography card analyser bottom, in test card stationary installation surveyed area, be provided with the positioning reed for fixed test card, even if rock, tilt instrument in practical operation, still can measure tested reagent, further improve the hand-portable of native system.
Be portable owing to taking formula immunity chromatography card analyser; often can be reversed or tilt in the course of the work; in testing process; pollute large reflective mirror, little reflective mirror and imaging sensor in order to prevent the detector leakage in test card; between described test card stationary installation and large reflective mirror, be provided with the cover glass that prevents from detecting liquid pollution detection storehouse, cover glass is detachable setting, in the time that detection contamination on glass has the liquid of detection; can disassemble and clean, recycling.
The beneficial effects of the utility model are: the portable immunochromatographiassays assays instrument of one of the present utility model, in the direct range of imaging sensor and test card at 2-6cm in the situation that, by twice mirror-reflection, final imaging sensor can obtain the effective image information of whole surveyed area, the thickness of whole instrument is reduced, further, adopt imaging mobile phone, mobile phone is thinner, can make the thickness of whole instrument further reduce, and has really embodied the feature of the hand-portable of POCT detection; Simultaneously, this twice mirror-reflection imaging arranges, make common imaging sensor just can in short-range focusing range, obtain the image of complete surveyed area, do not need the CCD of the high-end costliness of buying, CMOS photosensitive sensor, as the photo-sensitive cell of wide-angle, greatly reduce the manufacturing cost of traditional instrument, in analyser housing, be provided with LED light source group, its luminous energy sending is evenly distributed in the test card of loading in described stationary installation, imaging sensor can Quick Catch to the image of effective test card.
Brief description of the drawings
Below in conjunction with drawings and Examples, the utility model is further illustrated.
Fig. 1 is the structural representation of a kind of portable immunochromatographiassays assays instrument of the present utility model;
Fig. 2 is the fundamental diagram of a kind of portable immunochromatographiassays assays instrument of the present utility model;
Fig. 3 is the structural representation of the portable immunochromatographiassays assays instrument that relates to of preferred embodiment 2 of the present utility model;
Fig. 4 is the structural representation of the portable immunochromatographiassays assays instrument that relates to of preferred embodiment 3 of the present utility model;
Fig. 5 is the structural representation of the portable immunochromatographiassays assays instrument that relates to of preferred embodiment 4 of the present utility model;
Fig. 6 is the stereographic map of test card stationary installation of the present utility model.
In figure: 1. test card stationary installation, 2. large reflective mirror, 3. little reflective mirror, 4. imaging sensor, 5.LED light source group; 6. cover glass, 7. test card, 8. reflection ray, 11. positioning reeds; 51.LED light source battery, 52.LED light source control line plate, 53.LED lamp, 54. astigmatic bars.
Embodiment
Below in conjunction with specific embodiment, further the utility model is set forth, should be understood that and quote embodiment only for the utility model is described, and be not used in restriction scope of the present utility model.
Embodiment 1
As shown in Figure 1, portable immunochromatographiassays assays instrument provided by the utility model comprise for the test card stationary installation 1 of fixed test card position, for reflect test card stationary installation 1 surveyed area image large reflective mirror 2, for reflect 2 one-tenth of large reflective mirrors described surveyed area the little reflective mirror 3 of image and for catching the imaging sensor 4 of image of the described surveyed area that little reflective mirror 3 reflects.
Test card stationary installation 1 is long 5cm by the size of the general common test card of test card 7(like this, wide 2cm) position be fixed on surveyed area, large reflective mirror 2 is arranged on the top of surveyed area, its minute surface and the corresponding setting of test card 7 in surveyed area, large reflective mirror 2 minute surfaces become the angle of 15-30 ° with test card 7 place planes, the minute surface of little reflective mirror 3 arranges in opposite directions with the minute surface of large reflective mirror 2, and little reflective mirror 3 minute surfaces become the angle of 30-45 ° with test card 7 place planes.Its action principle as shown in Figure 2, the image of whole surveyed area is successively through the reflex of excessive reflective mirror 2 and little reflective mirror 3, final imaging sensor 4 can capture image (its imaging process is as shown in reflection ray in Fig. 2 8) complete, effective test card 7, realized direct range in imaging sensor 4 and test card 7 less, imaging sensor 4 can obtain effective test card 7 image informations, reaches the object of the thickness that reduces whole instrument.
Embodiment 2
As shown in Figure 3, portable immunochromatographiassays assays instrument provided by the utility model comprises the test card stationary installation 1 for fixed test card position, be used for the large reflective mirror 2 of the image that reflects test card stationary installation 1 surveyed area, for reflect 2 one-tenth of large reflective mirrors described surveyed area the little reflective mirror 3 of image and for catching the ccd imaging sensor 4 of image of the described surveyed area that little reflective mirror 3 reflects, portable immunochromatographiassays assays instrument provided by the utility model can also comprise LED light source group 5, LED light source group 5 comprises LED light source battery 51, LED light source control line plate 52 and LED lamp 53, LED light source battery 51 is controlled LED lamp 53 by LED light source control line plate 52, LED lamp 53 is arranged on surveyed area top periphery, be between test card stationary installation 1 and large reflective mirror 2, the outer astigmatic bar 54 that is fixed with the light uniformization for LED lamp 53 is sent of LED lamp 53.
In the time that imaging sensor 4 catches image, can open LED light source group 5, the luminous energy that LED light source group 5 is sent is evenly distributed in described test card stationary installation 1 in surveyed area, can further assist the image of imaging sensor 4 Quick Catchs to effective surveyed area.
Embodiment 3
As Fig. 4, shown in Fig. 6, portable immunochromatographiassays assays instrument provided by the utility model comprises the test card stationary installation 1 for fixed test card position, be used for the large reflective mirror 2 of the image that reflects test card stationary installation 1 surveyed area, for reflect 2 one-tenth of large reflective mirrors described surveyed area the little reflective mirror 3 of image and for catch the described surveyed area that little reflective mirror 3 reflects image can imaging mobile phone and LED light source group 5, LED light source group 5 comprises LED light source battery 51, LED light source control line plate 52 and LED lamp 53, LED light source battery 51 is controlled LED lamp 53 by LED light source control line plate 52, LED lamp 53 is arranged on surveyed area top periphery, be between test card stationary installation 1 and large reflective mirror 2, the outer astigmatic bar 54 that is fixed with the light uniformization for LED lamp 53 is sent of LED lamp 53, test card stationary installation 1 pull is loaded and unloaded on portable immunochromatographiassays assays instrument bottom, in test card stationary installation 1 surveyed area, be provided with the positioning reed 11 for fixed test card 7.
Test card stationary installation 1 is convenient to change test card 7, and can make test card 7 fix with respect to the position of portable immunochromatographiassays assays instrument, has avoided the error phenomenon bringing because of the change of test card 7 positions.
Even if rock, tilt instrument in practical operation, still can measure tested reagent, further improve the hand-portable of native system.
On the imaging basis of mobile phone, can utilize interior of mobile phone system, corresponding software is installed, analyzing and processing image, makes whole instrument small and exquisite, hand-held, has greatly reduced the high problem of cost of traditional instrument.
Embodiment 4
As Fig. 5, shown in Fig. 6, portable immunochromatographiassays assays instrument provided by the utility model comprises the test card stationary installation 1 for fixed test card position, be used for the large reflective mirror 2 of the image that reflects test card stationary installation 1 surveyed area, for reflect 2 one-tenth of large reflective mirrors described surveyed area the little reflective mirror 3 of image and for catch the described surveyed area that little reflective mirror 3 reflects image can imaging mobile phone and LED light source group 5, between test card stationary installation 1 and large reflective mirror 2, be provided with the cover glass 6 that prevents from detecting liquid pollution detection storehouse, LED light source group 5 comprises LED light source battery 51, LED light source control line plate 52 and LED lamp 53, LED light source battery 51 is controlled LED lamp 53 by LED light source control line plate 52, LED lamp 53 is arranged on test card 7 top peripheries, be between test card stationary installation 1 and large reflective mirror 2, the outer astigmatic bar 54 that is fixed with the light uniformization for LED lamp 53 is sent of LED lamp 53, test card stationary installation 1 pull is loaded and unloaded on portable immunochromatographiassays assays instrument bottom, in test card stationary installation 1 surveyed area, be provided with the positioning reed 11 for fixed test card 7.
Cover glass 6 can prevent that the residual liquid on reagent card from surprisingly entering test storehouse, pollutes reflective mirror and imaging sensor 4 etc.
In one, particularly in embodiment, portable immunochromatographiassays assays instrument provided by the utility model can carry out by stationary installations such as shells the restriction of its position.
Taking above-mentioned foundation desirable embodiment of the present utility model as enlightenment, by above-mentioned description, relevant staff can, not departing from the scope of this utility model technological thought, carry out various change and amendment completely.The technical scope of this utility model is not limited to the content on instructions, must determine its technical scope according to claim scope.
Claims (8)
1. a portable immunochromatographiassays assays instrument, is characterized in that comprising:
Test card stationary installation (1), described test card stationary installation (1) is provided with surveyed area;
Large reflective mirror (2), for reflecting the image of described test card stationary installation (1) surveyed area;
Little reflective mirror (3), for reflecting the image of the described surveyed area that large reflective mirror (2) becomes;
Imaging sensor (4), for catching the image of the described surveyed area that little reflective mirror (3) reflects.
2. portable immunochromatographiassays assays instrument as claimed in claim 1, is characterized in that: portable immunity chromatography card analyser also comprises LED light source group (5), its luminous energy sending is evenly distributed in the surveyed area in described test card stationary installation (1).
3. portable immunochromatographiassays assays instrument as claimed in claim 2, it is characterized in that: described LED light source group (5) comprises LED light source battery (51), LED light source control line plate (52) and LED lamp (53), LED light source battery (51) is controlled LED lamp (53) by LED light source control line plate (52), and described LED lamp (53) is fixedly installed between test card stationary installation (1) and large reflective mirror (2).
4. portable immunochromatographiassays assays instrument as claimed in claim 3, is characterized in that: the outer astigmatic bar (54) that is fixed with the light uniformization for LED lamp (53) is sent of described LED lamp (53).
5. portable immunochromatographiassays assays instrument as claimed in claim 1, is characterized in that: described imaging sensor (4) adopts COMS or ccd imaging sensor.
6. portable immunochromatographiassays assays instrument as claimed in claim 1, is characterized in that: described imaging sensor (4) is can imaging mobile phone.
7. the portable immunochromatographiassays assays instrument as described in claim 1-6 any one, it is characterized in that: described test card stationary installation (1) pull is loaded and unloaded on takes formula immunity chromatography card analyser bottom, is provided with the positioning reed (11) for fixed test card in test card stationary installation (1) surveyed area.
8. the portable immunochromatographiassays assays instrument as described in claim 1-6 any one, is characterized in that: between described test card stationary installation (1) and large reflective mirror (2), be provided with the cover glass (6) that prevents from detecting liquid pollution detection storehouse.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420092120.4U CN203732539U (en) | 2014-02-28 | 2014-02-28 | Portable immunochromatography analyzer |
| DE202015100937.2U DE202015100937U1 (en) | 2014-02-28 | 2015-02-26 | Portable immunochromatographic analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420092120.4U CN203732539U (en) | 2014-02-28 | 2014-02-28 | Portable immunochromatography analyzer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203732539U true CN203732539U (en) | 2014-07-23 |
Family
ID=51202602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420092120.4U Withdrawn - After Issue CN203732539U (en) | 2014-02-28 | 2014-02-28 | Portable immunochromatography analyzer |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN203732539U (en) |
| DE (1) | DE202015100937U1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103776998A (en) * | 2014-02-28 | 2014-05-07 | 常州思康立生物科技有限公司 | Portable immune-chromatography analysis meter |
| CN107462700A (en) * | 2016-06-02 | 2017-12-12 | 苏州泰坦医疗科技有限公司 | Immunochromatography hand-held analyzer |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10991185B1 (en) | 2020-07-20 | 2021-04-27 | Abbott Laboratories | Digital pass verification systems and methods |
-
2014
- 2014-02-28 CN CN201420092120.4U patent/CN203732539U/en not_active Withdrawn - After Issue
-
2015
- 2015-02-26 DE DE202015100937.2U patent/DE202015100937U1/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103776998A (en) * | 2014-02-28 | 2014-05-07 | 常州思康立生物科技有限公司 | Portable immune-chromatography analysis meter |
| CN103776998B (en) * | 2014-02-28 | 2015-06-10 | 常州思康立生物科技有限公司 | Portable immune-chromatography analysis meter |
| CN107462700A (en) * | 2016-06-02 | 2017-12-12 | 苏州泰坦医疗科技有限公司 | Immunochromatography hand-held analyzer |
Also Published As
| Publication number | Publication date |
|---|---|
| DE202015100937U1 (en) | 2015-06-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103776998B (en) | Portable immune-chromatography analysis meter | |
| CN102778455B (en) | Detection system for colloidal gold immunochromatographic assay (GICA) test paper | |
| CN107884396B (en) | Optical microscope-based ascorbic acid concentration online sensing analysis method and auxiliary color developing agent | |
| CN102183510B (en) | Colloidal gold detecting method and device based on digital image processing | |
| CN104155266A (en) | Multichannel parallel detection surface plasma resonance biosensor, and preparation and detection methods thereof | |
| CN101825640A (en) | Qualitative and quantitative detection dual-purpose HCG test paper for colloidal gold immunochromatography assay | |
| CN203732539U (en) | Portable immunochromatography analyzer | |
| CN104101580A (en) | BRDF quick measuring device based on hemisphere array detection | |
| CN206772438U (en) | Absorption and fluorescence spectrum detecting device based on mobile intelligent terminal | |
| CN103808918A (en) | Image-sensor-based detection system of colloidal gold immunoassay | |
| CN102608042B (en) | Method for extrinsic allergen quantitative detection based on multispectral imaging | |
| CN108680759A (en) | A kind of Multifunctional high flux automation chromatographic detector and its application | |
| CN102183301A (en) | Portable type unified glare measuring apparatus | |
| CN108387542A (en) | Fluorine ion colorimetric sensor and its application in a kind of water based on smart mobile phone | |
| CN105784706A (en) | Rapid aflatoxin B1 detecting method based on smartphone detecting system | |
| Xing et al. | A cellphone-based colorimetric multi-channel sensor for water environmental monitoring | |
| CN207600954U (en) | A kind of portable colour comparison detection apparatus | |
| WO2017063599A1 (en) | Turbidity sensor used by mobile terminal for protein or nucleic acid analysis | |
| Shah et al. | ImageQuant: An image-based quantitative Immunoassay Analyzer | |
| CN101592606B (en) | Portable surface plasma resonance biochemical analyzer | |
| CN101726587A (en) | Instrument for indentifying and quantitatively analyzing image of immune test paper in moving process | |
| CN107462700A (en) | Immunochromatography hand-held analyzer | |
| CN106324205A (en) | Detection darkroom for food safety fast detector | |
| CN105929149A (en) | Optical detector based on magnetic enrichment and total internal reflection | |
| CN106153537A (en) | The optical scanner of a kind of colloid gold immune quantitative analysis instrument and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20140723 Effective date of abandoning: 20150610 |
|
| AV01 | Patent right actively abandoned |
Granted publication date: 20140723 Effective date of abandoning: 20150610 |
|
| RGAV | Abandon patent right to avoid regrant |