CN203507317U - Bladder autonomous control system under 3D ultrasonic image navigation - Google Patents
Bladder autonomous control system under 3D ultrasonic image navigation Download PDFInfo
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- CN203507317U CN203507317U CN201320665127.6U CN201320665127U CN203507317U CN 203507317 U CN203507317 U CN 203507317U CN 201320665127 U CN201320665127 U CN 201320665127U CN 203507317 U CN203507317 U CN 203507317U
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Abstract
The utility model discloses a bladder autonomous control system under 3D ultrasonic image navigation, which comprises a 3D ultrasonic probe, a power supply module, a first field programmable gate array, a second field programmable gate array, a pulse amplification unit, an electrode array module and a therapeutic information preservation module, wherein the 3D ultrasonic probe is used for obtaining bladder 3D data in real time; the power supply module is used for providing power for the system; the first field programmable gate array is connected with the 3D ultrasonic probe; the second field programmable gate array is respectively connected with the first field programmable gate array and a temperature sensing device which is arranged on the electrode array module and used for monitoring electrode temperature in real time; the pulse amplification unit is connected with an output end of the second field programmable gate array; the electrode array module is connected with an output end of the pulse amplification unit; and the therapeutic information preservation module is connected with the second field programmable gate array. According to the bladder autonomous control system, the position of a bladder is accurately located through ultrasonic 3D images, the positions of a detrusor and an external urethral sphincter are determined according to the physiological structure, the detrusor and the external urethral sphincter are stimulated with pulses of different frequencies and amplitudes, and the micturition process can be finished by stimulating the bladder accurately and non-invasively under 3D ultrasonic navigation.
Description
Technical field
This utility model relates to a kind of promotion automatic micturition system.Particularly relate to the bladder self-control system under a kind of three-D ultrasonic image navigation that is used for the treatment of the urinary dysfunction that spinal cord injury causes.
Background technology
Spinal cord is the elementary micturition centre of controlling detrusor and urethra flesh, external sphincter functional activity, is also the co-channel between the vesicourethral sensation impulsion of conduction and senior micturition centre.Spinal cord injury refers to that extraneous directly or indirectly factor causes the infringement of spinal cord structure and function, causes the obstacle of the following function of spinal nerves of level of damage.According to spinal cord injury person committee 2011 statistics, approximately there are 1,000,000 spinal cord injury persons in China, and with annual 10000 people's speed increase.Neurogenic bladder is one of spinal cord injury complication, main manifestations is that residual urine volume increases, urine retention and urinary incontinence etc., if treatment not in time, may cause a series of complication such as urinary system infection, renal calculus, hydronephrosis, severe patient can cause renal function decay, be the main cause of death due to spinal cord injury, bring huge injury to patient family and society.
For vesical dysfunction Therapeutic Method, mainly comprise urethral catheterization, operative treatment, magnetic irritation therapy and electrical stimulating therapy etc. at present.Urethral catheterization easily causes urinary tract infection and makes troubles to patient's life, and operative treatment and implantation type electric stimulation are treated to patient and brought huge misery and expensive, and magnetic stimulation treatment is difficult to stimulate the degree of depth neural.The desirable method for the treatment of vesical dysfunction is electrical stimulation method, but there is following shortcoming in existing electro stimulation treatment apparatus: 1) definite not science of electricity irritation position, as Chinese patent portable non-invasive bladder therapeutic instrument (200910104124.3), electrode paste is put in to bladder acupuncture point around, but its design cannot be from external acquisition bladder positional information, can not regulate electricity irritation position according to the bladder of different people, stimulation sites does not have science.2) the bladder shape in process of urinating, size all can change, this can cause electricity irritation to be lost efficacy, present stage equipment cannot change and adjust stimulation point position according to this, increase ineffective stimulation simultaneously.3) cannot distinguish and stimulate inefficacy and urine emptying, Bladder Volume is not monitored in real time, without residual urine amount feedback mechanism, be can not determine whether urine has residual, can only be to stop stimulating or random transposition stimulation in inefficacy, this can cause electricity irritation excessively or urine retention.
Summary of the invention
Technical problem to be solved in the utility model is, a kind of urinary dysfunction therapy system with positioning function is provided, can be under three-D ultrasonic navigation accurately and noinvasive stimulate bladder to complete the bladder self-control system under the three-D ultrasonic image navigation of the process of urinating.
The technical scheme that this utility model adopts is: the bladder self-control system under the navigation of a kind of three-D ultrasonic image, include the three dimensional ultrasound probe of real-time acquisition bladder three-dimensional data, for the power module of power supply is provided to system, and be also provided with:
Primary scene programmable gate array, is connected with described three dimensional ultrasound probe, for receiving bladder three-dimensional data, carries out three-dimensional reconstruction and obtains bladder 3-dimensional image and Bladder Volume information;
Secondary scene programmable gate array, respectively with described primary scene programmable gate array and be arranged on electrod-array module on for the temperature sensing device of Real-Time Monitoring electrode temperature, be connected, according to the relative position relation of Bladder Volume information and three-dimensional probe and electrod-array module and real-time electrode temperature, determine whether the position and the intensity that start or close electricity irritation and start electricity irritation, and export corresponding pulse signal;
Pulse Amplifier Unit, is connected with the output of described secondary scene programmable gate array, receives and amplifies the pulse signal that secondary scene programmable gate array is exported, and exporting to electrod-array module;
Electrod-array module, is connected with the outfan of described Pulse Amplifier Unit, according to the signal of Pulse Amplifier Unit output, electricity irritation is carried out in patient relevant position and help to urinate;
Treatment information is preserved module, connects secondary scene programmable gate array, the electrode position and the stimulation time that for storing bladder structure figure and treatment overall process, use.
Also be provided with the keyboard being connected with the signal input part of described secondary scene programmable gate array, and the display unit being connected with the signal output part of described secondary scene programmable gate array.
Described electrod-array module is waistband type electrod-array module, the both sides that include main body, are connected to main body are for the fixing tension belt of waist be evenly distributed on n absolute electrode in main body, the central part of described main body is formed with for inserting the reserved window of three dimensional ultrasound probe, a described n electrode connects respectively Pulse Amplifier Unit, and described n is 48～100 integer.
Described Pulse Amplifier Unit includes the identical pulse amplification module of n structure with n the corresponding connection of electrode set in electrod-array module, wherein any pulse amplification module all includes a DA modular converter U1, a first operational amplifier U2 and a second operational amplifier U3, wherein, the reference voltage end of described DA modular converter U1 connects for the constant pressure source V of constant voltage is provided
rEF, this reference voltage end is also passed through respectively capacitor C
1and capacitor C
2ground connection, and pass through resistance R
1the inverting input that connects the first operational amplifier U2, the signal input part of described DA modular converter U1 connects the signal output part of secondary scene programmable gate array, the outfan of described DA modular converter U1 connects the in-phase input end of the first operational amplifier U2, and the inverting input of described the first operational amplifier U2 passes through resistance R
2the outfan that connects the first operational amplifier U2, the outfan of the first operational amplifier U2 connects C by electric capacity
3the in-phase input end that connects the second operational amplifier U3, the outfan of described the first operational amplifier U2 also passes through respectively resistance R
3ground connection, and connection+5V voltage and-5V voltage, the in-phase input end of described the second operational amplifier U3 also passes through resistance R
4ground connection, the inverting input of described the second operational amplifier U3 passes through resistance R successively
5and capacitor C
4ground connection, the inverting input of this second operational amplifier U3 also passes through resistance R
6connect the outfan of the second operational amplifier U3, the outfan of described the second operational amplifier U3 connects an electrode in n electrode set in described electrod-array module, and this outfan also passes through resistance R successively
7and capacitor C
7ground connection, described the second operational amplifier U3 also connects voltage V
cCand constant negative pressure-V
eE.
Bladder self-control system under three-D ultrasonic image navigation of the present utility model, the urinary dysfunction therapy system with positioning function, by ultrasonic three-dimensional image, accurately locate bladder position, and can determine according to physiological structure the position of detrusor and the musculus sphincter of external urethra, and with impulse stimulation detrusor and the musculus sphincter of external urethra of different frequency and amplitude, can be under three-D ultrasonic navigation accurately and noinvasive stimulate bladder to complete the process of urinating, with noinvasive means, help patient's automatic micturition, help patient to reduce residual urine, urine retention.This utility model shows bladder tomograph in real time by three dimensional ultrasound probe and three-dimensional reconstruction algorithm, can adjust in real time stimulation sites, guarantees the effectiveness and the accuracy that stimulate; By waistband type electrod-array module, according to the bladder degree of depth of electrode position and muscle attribute, determine the pulse signal of optimum frequency and intensity, guarantee optimal stimulus effect; By bladder tomograph, determine urine amount residual volume, guarantee to stimulate to stop in time, avoid ineffective stimulation and overstimulation.This utility model accurate positioning, stimulation pulse signal select that science, volume are little, price economy, easy to operate, to patient's noinvasive, have no side effect, are applicable to the urinary dysfunction patient of family or hospital.
Accompanying drawing explanation
Fig. 1 is the whole structural representation that forms of the present utility model;
Fig. 2 is the structural representation of electrod-array module of the present utility model;
Fig. 3 is the circuit theory diagrams of Pulse Amplifier Unit of the present utility model;
Fig. 4 is the structural representation of three-D ultrasonic control head of the present utility model;
Fig. 5 is use-case of the present utility model;
Fig. 6 is the panel schematic diagram of this utility model keyboard.
In figure
The specific embodiment
Below in conjunction with embodiment and accompanying drawing, the bladder self-control system under three-D ultrasonic image navigation of the present utility model is described in detail.
According to mechanics of muscle principle, the human body process of urinating is by shrinking detrusor, intravesical pressure to be increased, and with suppressing the musculus sphincter of external urethra, urethra is opened, and two groups of muscle synergism complete the thing of urinating.In human body, detrusor belongs to smooth muscle, and the musculus sphincter of external urethra belongs to striped muscle, striped muscle there will be fatigue under high-frequency pulse stimulates, contractility declines urethra is opened, and smooth muscle easily shrinks under low frequency signals, under high-frequency pulse stimulates, is prone to tic.Therefore, apply the electricity irritation of different frequency to two kinds of muscle, musculus sphincter of external urethra diastole when can realize detrusor contractions, finally makes urine excrete.
According to These characteristics, this utility model provides a kind of electrod-array module is combined with three dimensional ultrasound probe, can locate detrusor of bladder and the musculus sphincter of external urethra, simultaneously according to the muscle degree of depth of living in, determine with different frequency and pulse strength and stimulate detrusor and the musculus sphincter of external urethra, complete the system of the micturition of once coordinating.
As shown in Figure 1, the bladder self-control system under three-D ultrasonic image of the present utility model navigation, includes the three dimensional ultrasound probe 10 of real-time acquisition bladder three-dimensional data, for the power module 9 of power supply is provided to system, is also provided with:
Primary scene programmable gate array (FPGA) 2, is connected with described three dimensional ultrasound probe 10, for receiving bladder three-dimensional data, carries out three-dimensional reconstruction obtain bladder 3-dimensional image and Bladder Volume information by formation three-dimensional reconstruction resume module within it;
Secondary scene programmable gate array (FPGA) 1, as control section, respectively with described primary scene programmable gate array 2 and be arranged on electrod-array module 4 on for the temperature sensing device 5 of Real-Time Monitoring electrode temperature, be connected, according to the relative position relation of Bladder Volume information and three-dimensional probe 10 and electrod-array module 4 and real-time electrode temperature, determine whether to start or close position and the intensity that electricity irritation help is urinated and started electricity irritation, and export corresponding pulse signal.When determining while need start to urinate, by the three-dimensional localization module forming within it, position, then according to three-dimensional probe 10 relative position relation with waistband type electrod-array module 4, determine the electricity irritation position that should start.Temperature sensing device 5 described in the utility model can adopt temperature sensor.
Secondary scene programmable gate array (FPGA) 1 integrated level as control module is very high, can complete complicated sequential and combinational logic circuit function.Control module major function is to produce physiology pulse signal and control impuls amplifying unit, electrod-array module.Theoretical according to relevant medical, the frequency of 1～10Hz can cause the single contraction of muscle, and 20～30Hz can cause the incomplete tetanic contraction of muscle, and 50Hz can cause that the complete tetanus of muscle shrinks.Thus, the pulse frequency of this bladder automatic micturition system control module output is 1～100Hz.Output pulse signal should meet the pulse of Human Physiology characteristic, realizes the selective stimulating to the muscle of bladder.Employing has the stimulus waveform of polarity to excite nerve, and can cause the damage of muscular tissue around the discomfort at incidental stimulus position, and adopt non-polar stimulus waveform, can reduce the damage of muscular tissue.This bladder automatic micturition system design adopts diphasic pulse ripple.
Electrod-array module 4, is connected with the outfan of described Pulse Amplifier Unit 3, according to the signal of Pulse Amplifier Unit 3 outputs, electricity irritation is carried out in patient relevant position and help to urinate;
Treatment information is preserved module 7, connect secondary scene programmable gate array 1, major function is for preserving patient's case, and the electrode position and the stimulation time that in storage bladder structure figure and treatment overall process, use facilitate doctor's later observation and diagnosis and patient's treatment next time.
Also have the keyboard 8 being connected with the signal input part of described secondary scene programmable gate array 1, and the display unit 6 being connected with the signal output part of described secondary scene programmable gate array 1.
As shown in Figure 2, described electrod-array module 4 is waistband type electrod-array module, the both sides that include main body 44, are connected to main body 44 are for the fixing tension belt 41 of waist be evenly distributed on n absolute electrode 42 in main body 44, the central part of described main body 44 is formed with for inserting the reserved window 43 of three dimensional ultrasound probe 10, a described n electrode 42 connects respectively Pulse Amplifier Unit 3, and described n is 48～100 integer.
The electrod-array consisting of the electrode that can independently control in waistband type electrod-array module is anyhow to intersect regular mode proper alignment, and each electrode slice can be exported respectively the pulse signal of different frequency and intensity, to stimulate the muscle at bladder diverse location place.The circular hole that stays in the middle of waistband type electrod-array module, for placing three dimensional ultrasound probe place, according to information such as the scan mode of probe and investigation depths, determines the relative position relation of ultrasonic three-dimensional image and electrode.Waistband type electrod-array module can be fixed on by the tension belt of both sides patient's hypogastric region.Waistband type electrod-array module is controlled by secondary scene programmable gate array 1, according to bladder three-dimensional reconstruction result.
As shown in Figure 5, described electrod-array module 4, is fixed on patient's hypogastric region by tension belt 41, and three dimensional ultrasound probe is placed in to belt electrod-array module centre position, according to information such as the scan mode of probe and investigation depths, determine the relative position relation of ultrasonic three-dimensional image and electrode.In the electrode of a plurality of independent transmission electric impulse signals, the intensity of the chong channel signal of each electrode and frequency can, according to temperature sensing device 5 and 10 feedacks of three dimensional ultrasound probe, be determined by the bladder degree of depth and the muscle attribute of electrode 42 positions adaptively.Conventionally, to detrusor of bladder, use low frequency pulse signal to stimulate, to the musculus sphincter of external urethra, use high-frequency pulse signal to stimulate, make detrusor contractions musculus sphincter of external urethra diastole simultaneously, with noninvasive means, help urinary dysfunction patient to complete the automatic micturition of once coordinating.
As shown in Figure 3, described Pulse Amplifier Unit 3 includes the identical pulse amplification module of n structure with n electrode 42 corresponding connections set in electrod-array module 4, wherein any pulse amplification module all includes a DA modular converter U1, a first operational amplifier U2 and a second operational amplifier U3, wherein, the reference voltage end of described DA modular converter U1 connects for the constant pressure source V of constant voltage is provided
rEF, this reference voltage end is also passed through respectively capacitor C
1and capacitor C
2ground connection, and pass through resistance R
1the inverting input that connects the first operational amplifier U2, the signal input part of described DA modular converter U1 connects the signal output part of secondary scene programmable gate array 1, the outfan of described DA modular converter U1 connects the in-phase input end of the first operational amplifier U2, and the inverting input of described the first operational amplifier U2 passes through resistance R
2the outfan that connects the first operational amplifier U2, the outfan of the first operational amplifier U2 connects C by electric capacity
3the in-phase input end that connects the second operational amplifier U3, the outfan of described the first operational amplifier U2 also passes through respectively resistance R
3ground connection, and connection+5V voltage and-5V voltage, the in-phase input end of described the second operational amplifier U3 also passes through resistance R
4ground connection, the inverting input of described the second operational amplifier U3 passes through resistance R successively
5and capacitor C
4ground connection, the inverting input of this second operational amplifier U3 also passes through resistance R
6connect the outfan of the second operational amplifier U3, the outfan of described the second operational amplifier U3 connects an electrode in n electrode set in described electrod-array module 4, and this outfan also passes through resistance R successively
7and capacitor C
7ground connection, described the second operational amplifier U3 also connects voltage V
cCand constant negative pressure-V
eE.
Fig. 4 is three dimensional ultrasound probe 10 described in the utility model, includes piezoquartz 103 and the 360 degree electric rotating machines 101 that are connected with piezoquartz 103 respectively and 120 degree fan-shaped rotary motors 102.The collection that three dimensional ultrasound probe 10 is realized bladder ultrasonic signal, in this utility model, adopting three dimensional ultrasound probe mid frequency is 2.5MHz, and scan mode is two-dimensional array formula, and three dimensional ultrasound probe is placed in electrod-array centre position.Three dimensional ultrasound probe gathers ultrasonic signal and transfers to three-dimensional reconstruction module, after three-dimensional reconstruction algorithm is rebuild, shows bladder structure figure, in order to realize the accurate location to bladder electricity irritation.According to three-dimensional bladder reconstruction structure chart, control module is adjusted the output pulse signal of electrod-array, realizes the accurate stimulation to bladder.
Power module 9 of the present utility model, for each device of native system provides suitable voltage, adopts battery powered.In this module, by manostat, voltage is become to 3.3V, 1.5V, 5V, wherein 3.3V, 1.5V provide I/O voltage and core operational voltage to FPGA respectively.Near manostat, use inductance and electric capacity filtering voltage ripple.
Keyboard 9 comprises: initiating key 91, stop key 92, preserve key 93, time key 94,, strength key 95, frequency key 96, position options button 97, upwarding key 98, left Arrow 99, right key 910, down Arrow 911, its panel construction is as shown in Figure 6.By the initiating key on keyboard, start this utility model; Stop key is for stopping the process of current operation; Time key, frequency key, strength key are used for respectively regulating time, frequency and the intensity of electricity irritation; Position options button, upwarding key, down Arrow, left Arrow, right key are used for selecting stimulation sites, preserve key and are used for preserving treatment information.
In this utility model, each electrode can be launched different pulse signals simultaneously, this pulse signal is produced by secondary scene programmable gate array, and amplify through extra pulse amplification module, the outfan link waistband type electrod-array module of pulse amplification module, by corresponding electrode, output to human body again, after having treated, treatment information is preserved electrode position and the stimulation time using in module stores bladder structure figure and treatment overall process, power module provides running voltage for described each device of bladder automatic micturition system, keyboard starts and controls described bladder automatic micturition system, temperature sensing device Real-Time Monitoring electrode temperature.
The workflow of the bladder self-control system under three-D ultrasonic image navigation of the present utility model is:
1) in advance for patient sets the Bladder Volume lowest threshold that needs to start treatment;
2) three dimensional ultrasound probe is positioned over to waistband type electrod-array module centers reserved window place, by three dimensional ultrasound probe, finds behind patient's bladder position, use the tension belt of waistband type electrod-array module that the two is fixed;
3) primary scene programmable gate array 2 calculates Bladder Volume at that time by three-dimensional reconstruction, if arrive, preset lowest threshold,, by three-dimensional localization module, determine information such as needing the position of stimulation and muscle attribute, and pass to secondary scene programmable gate array 1;
4) according to these information, secondary scene programmable gate array 1 as control module is controlled waistband type electrod-array module, select effective electricity irritation position, the nerve of take is main stimulation point with detrusor junction and the musculus sphincter of external urethra, to detrusor, adopt low-frequency pulse to stimulate, to the musculus sphincter of external urethra, adopt high-frequency impulse to stimulate, stimulus intensity is determined apart from the position relationship of electrode according to patient's sensitivity and muscle;
5) urinate bladder shape and size in process can change, and this can make electricity irritation lose efficacy, and now should pass through three-dimensional bladder real time imaging, redefines stimulation point;
6) when urinating, stop, stopping electricity irritation, enable three-dimensional ultrasonography volume and detect, if urine one is emptying, complete this treatment, preserve treatment information;
7) if still have residual urine volume to adjust electricity irritation position, suitably increase stimulus intensity, again start electricity irritation;
8) repeat 4) to 7) process, until treated.
Bladder self-control system under three-D ultrasonic image navigation of the present utility model, by three-D ultrasonic, survey the combination of appearance and electricity irritation, the accurate location of realization to bladder electricity irritation, simultaneously to different muscle with different frequency stimulations, help the noninvasive realization of patient to urinate, the contraction urinary function that replaces bladder to lose.In the muscle that excites nerve, also stimulate nervus centripetalis, add the motor pattern information of continuous repetition, afferent nervous system, helps patient to recover gradually the original motor function of bladder.
Claims (4)
1. the bladder self-control system under three-D ultrasonic image navigation, includes the three dimensional ultrasound probe (10) of real-time acquisition bladder three-dimensional data, for the power module (9) of power supply is provided to system, it is characterized in that, is also provided with:
Primary scene programmable gate array (2), is connected with described three dimensional ultrasound probe (10), for receiving bladder three-dimensional data, carries out three-dimensional reconstruction and obtains bladder 3-dimensional image and Bladder Volume information;
Secondary scene programmable gate array (1), respectively with described primary scene programmable gate array (2) and be arranged on the upper temperature sensing device (5) for Real-Time Monitoring electrode temperature of electrod-array module (4) and be connected, according to the relative position relation of Bladder Volume information and three-dimensional probe (10) and electrod-array module (4) and real-time electrode temperature, determine whether the position and the intensity that start or close electricity irritation and start electricity irritation, and export corresponding pulse signal;
Pulse Amplifier Unit (3), is connected with the output of described secondary scene programmable gate array (1), receives and amplifies the pulse signal that secondary scene programmable gate array (1) is exported, and exporting to electrod-array module (4);
Electrod-array module (4), is connected with the outfan of described Pulse Amplifier Unit (3), according to the signal of Pulse Amplifier Unit (3) output, electricity irritation is carried out in patient relevant position and help to urinate;
Treatment information is preserved module (7), connects secondary scene programmable gate array (1), the electrode position and the stimulation time that for storing bladder structure figure and treatment overall process, use.
2. the bladder self-control system under three-D ultrasonic image according to claim 1 navigation, it is characterized in that, also be provided with the keyboard (8) being connected with the signal input part of described secondary scene programmable gate array (1), and the display unit (6) being connected with the signal output part of described secondary scene programmable gate array (1).
3. the bladder self-control system under three-D ultrasonic image according to claim 1 navigation, it is characterized in that, described electrod-array module (4) is waistband type electrod-array module, include main body (44), the both sides that are connected to main body (44) are used for the tension belt (41) fixing with waist and are evenly distributed on n the absolute electrode (42) in main body (44), the central part of described main body (44) is formed with the reserved window (43) for inserting three dimensional ultrasound probe (10), a described n electrode (42) connects respectively Pulse Amplifier Unit (3), described n is 48～100 integer.
4. according to the bladder self-control system under the three-D ultrasonic image navigation described in claim 1 or 3, it is characterized in that, described Pulse Amplifier Unit (3) includes the identical pulse amplification module of n structure with the corresponding connection of n electrode (42) set in electrod-array module (4), wherein any pulse amplification module all includes a DA modular converter U1, a first operational amplifier U2 and a second operational amplifier U3, wherein, the reference voltage end of described DA modular converter U1 connects for the constant pressure source V of constant voltage is provided
rEF, this reference voltage end is also passed through respectively capacitor C
1and capacitor C
2ground connection, and pass through resistance R
1the inverting input that connects the first operational amplifier U2, the signal input part of described DA modular converter U1 connects the signal output part of secondary scene programmable gate array (1), the outfan of described DA modular converter U1 connects the in-phase input end of the first operational amplifier U2, and the inverting input of described the first operational amplifier U2 passes through resistance R
2the outfan that connects the first operational amplifier U2, the outfan of the first operational amplifier U2 connects C by electric capacity
3the in-phase input end that connects the second operational amplifier U3, the outfan of described the first operational amplifier U2 also passes through respectively resistance R
3ground connection, and connection+5V voltage and-5V voltage, the in-phase input end of described the second operational amplifier U3 also passes through resistance R
4ground connection, the inverting input of described the second operational amplifier U3 passes through resistance R successively
5and capacitor C
4ground connection, the inverting input of this second operational amplifier U3 also passes through resistance R
6connect the outfan of the second operational amplifier U3, the outfan of described the second operational amplifier U3 connects an electrode in n electrode set in described electrod-array module (4), and this outfan also passes through resistance R successively
7and capacitor C
7ground connection, described the second operational amplifier U3 also connects voltage V
cCand constant negative pressure-V
eE.
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| CN201320665127.6U CN203507317U (en) | 2013-10-25 | 2013-10-25 | Bladder autonomous control system under 3D ultrasonic image navigation |
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| CN201320665127.6U CN203507317U (en) | 2013-10-25 | 2013-10-25 | Bladder autonomous control system under 3D ultrasonic image navigation |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103611218A (en) * | 2013-10-25 | 2014-03-05 | 中国医学科学院生物医学工程研究所 | A bladder automatic urinating system guided by ultrasonic three-dimensional images |
| CN109481844A (en) * | 2018-12-27 | 2019-03-19 | 清华大学 | Implantable nerve stimulation apparatus with multiple-frequency-mode |
| CN109603003A (en) * | 2018-10-25 | 2019-04-12 | 中国中医科学院针灸研究所 | A kind of system based on 3D printing ear mold treatment depression |
-
2013
- 2013-10-25 CN CN201320665127.6U patent/CN203507317U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103611218A (en) * | 2013-10-25 | 2014-03-05 | 中国医学科学院生物医学工程研究所 | A bladder automatic urinating system guided by ultrasonic three-dimensional images |
| CN109603003A (en) * | 2018-10-25 | 2019-04-12 | 中国中医科学院针灸研究所 | A kind of system based on 3D printing ear mold treatment depression |
| CN109603003B (en) * | 2018-10-25 | 2024-03-19 | 中国中医科学院针灸研究所 | Ear mold treatment system based on 3D printing |
| CN109481844A (en) * | 2018-12-27 | 2019-03-19 | 清华大学 | Implantable nerve stimulation apparatus with multiple-frequency-mode |
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| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140402 Termination date: 20151025 |
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| EXPY | Termination of patent right or utility model |