CN201189412Y

CN201189412Y - Filter for collecting the infection source substance in blood

Info

Publication number: CN201189412Y
Application number: CNU2008200632213U
Authority: CN
Inventors: 王新平
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-04-30
Filing date: 2008-04-30
Publication date: 2009-02-04
Anticipated expiration: 2018-04-30

Abstract

The utility model relates to a filter for collecting infection source substances in blood, wherein a filter core structure is clamped inside an internal receiving cavity which is formed by two shells with closed circumferences on two sides; the circumferential edge of the filter core structure is also hermetically fixed with circumferences of the shells; the two shells on the two sides are respectively provided with a liquid guide pipe capable of being communicated with the inside and the outside of the internal receiving cavity; and internal openings of liquid guide pipes are respectively positioned on both sides of a filtering path of the filter core structure, wherein the filtering pore diameter of the filter core structure is between 15 and 80 micrometers. The filter can catch and collect infection source components in the blood of infective disease patients such as malignant bacteria and so on, and not only can be used by medical lab staff to quickly analyze and judge the type of the malignant infection sources, is convenient for doctors to diagnose and treat symptomatically and has great significance and value in the aspects of preventing abuse of antibiotic medicines currently and causing quick pervasion of drug resistant bacteria and so on, but also can be taken as an auxiliary tool and device for retarding the symptom of emergent patients.

Description

Be used for collecting the filter of blood source of infection class material

Technical field

The utility model relates to a kind of filtration utensil of blood constituent, more specifically say it is a kind of filter that can be used for collecting source of infection class material such as malignant bacteria in the blood, can before treatment, infective pathogen body composition accurately be analyzed and judge, can be used for human or animal's infectious diseases diagnosis.

Background technology

In people or animal are subjected to initial stage and/or PD process that malignant bacteria, mycoplasma etc. infect, conventional blood testing can only be checked out in the blood variation as leucocyte blood picture indexs such as (comprising band form neutrophilic granulocyte, neutrophilic segmented granulocyte, EC, basophil, lymphocyte), because pathogenic microorganism quantity such as external pathogenic bacteria are still insufficient, the former kind of can't analysis and judgement causing a disease, caused often being difficult to use the specificity sensitive medicaments to have at ground clinically and treated, common practice is to adopt the strong effect wide-spectrum antibiotic.Broad-spectrum antibiotic not only can not kill or suppress pathogen such as pathogenic bacteria sometimes specifically, also can increase the drug resistance that pathogenic bacteria etc. produce antibiotic and affects valuable treatment time adversely, even cause the state of an illness to further develop and increase the weight of.As not using antibiotic in early days; pathogen in the wait body is bred a great deal of; when can be the routine test detection and judging its type; often delayed best effective treatment time; not only with the use antibiotic more efficiently of having to that increases the weight of of the state of an illness, regular meeting causes and can't give treatment to because of delay treatment.This is the one of the main reasons of current excess or abuse of antibiotics, also is that new drug development speed is unable to catch up with the develop immunity to drugs major reason of speed of pathogenic bacteria.

Existing research is understood, and the leucocyte in human body or the animal blood tissue has active chemotactic locomotivity, and they can be moved to outside the blood vessel or from extravascular tissue in blood vessel and move in the blood vessel.Leucocyte removes and is present in blood and lymph China and foreign countries, also extensively is present in blood vessel, the lymphatic vessel tissue in addition.Volume as the exotic invasive malignant bacteria of infectious diseases is about 10-20 μ m, and is roughly the same with the volume of each blood constituent cell.When body produces specific immune response, having a plurality of leucocytes at single invasion malignant bacteria wraps up and engulfs, form one " immune aggregation cell mass ", and its variable volume surpasses the several times of each the composition cell of blood that comprises leucocyte greatly.

The utility model content

Given this, the utility model will be on the basis of existing blood component filter, a kind of filter that can be used for filtering, collecting the source of infection class materials such as malignant bacteria in the blood is provided, for before the treatment infective pathogen body composition accurately being analyzed and is judged, and the diagnosis of human or animal's infectious diseases.

For realizing the filter utility of some haemocyte composition in the corresponding medical purpose filtering blood, existing at home and abroad report and/or use.Wait the leukocyte depletion filter of all having reported the different structure form in some Chinese patents respectively for the blood transfusion use as the patent No. 200720079021.2 and 200720080497.8, its mentality of designing and requirement all are that leucocyte is had high as far as possible rejection rate even wishes to filter leucocyte to the greatest extent.And national pharmaceuticals industry standard YY0329-2002 to " disposable use leucocyte-removing filter " also regulation require to reach leukocytic remainder and be less than 2.5 * 10 ⁶, and the few more quality of the leukocytic surplus of product filtering is high more.

Discovering that based on aforesaid be to realize the purpose of this utility model, said this is used for collecting the filter of blood source of infection class material, is a kind of mentality of designing that proposes on above-mentioned blood cell filter basis and the improvement of version.Its structure is to be gripped with filter cartridge construction in the content cavity that two side bodies by border seal form, the periphery of filter cartridge construction also with the mutually sealing of periphery of housing, respectively be provided with a catheter that can be communicated with inside and outside its content cavity on two side bodies, the internal orifice of catheter lays respectively at the both sides that filter cartridge construction filters path, wherein the pore size filter of this filter cartridge construction should be greater than 15 microns, better the filter opening scope is the 15-80 micron, particularly the 25-80 micron.

Be appreciated that by above-mentioned analysis the purpose of utility model of the present invention is not is to want the normal haemocyte composition of filtering, but increase " the immune aggregation cell mass " of several times at immunocytes such as leucocyte formed volume when attacking external source of infection material.For this reason, filter of the present utility model should be let slip the various haemocyte compositions under the normal condition as far as possible, only filter and collected volume significantly greater than " the immune aggregation cell mass " of normal plasma cell composition.Therefore should to have suitable filter opening scope be essential with important to filter cartridge construction.Said filter cartridge construction can be for having the material that stops the various versions of filtration, as the nonwoven that formed by materials processings such as polyester, nylon, polypropylene, glass fibre, stainless steels or braiding structure etc.

On the basis of above-mentioned simple barrier type filtration mechanism and process, for realizing having better filter effect, the further improvement of the utility model measure, be that said this filter cartridge construction is adopted as by the lamellar fibre material through ungrease treatment, as be commonly used for stacked the forming such as nonwoven of material for core, the suction-operated of normal plasma cell composition can more be waltzed through in filter process to reduce material for core, reduce influence haemocyte composition under the normal condition.

Use when making things convenient for next step check and analysis for conveniently filtering and collect the above-mentioned filter of the utility model that required source of infection material is arranged, said this two side body in the above-mentioned filter that is used for collecting blood source of infection class material, though can make, be good with the form that all adopts flexible material by the various materials that comprise hard material.Operating personnel extract pathogenic bacteria in the filter by simple cutting and separating mode.

Said catheter in the above-mentioned filter that is used for collecting blood source of infection class material can also be provided with dismountable jointing (as female Luer commonly used etc.), when making things convenient for the actual use of this filter with being connected of other related equipment or equipment.

The above-mentioned filter of the utility model can be according to the kind distribution of bacterium and the needs of filtering blood flow, manufacture multiple different size and model, according to the light and heavy degree of infected individuals illness,, adopt respectively and catch the bacterium of collecting in its blood by filtering 100～1000 milliliters blood.Concrete occupation mode can be connected to this filter that continuous filtration obtains required source of infection material in the extracorporal circulatory system equipment, or is connected in the pipeline of collection containers such as disposable blood collecting containers bag commonly used in blood sampling mode commonly used.

Because can catching and collect malignant bacteria etc., the above-mentioned filter of the utility model infects source of infection composition in the class disease blood samples of patients, it both can judge the type of the source of infection of causing a disease for medical test personnel express analysis, be convenient to that the doctor makes a definite diagnosis and the medication of suiting the medicine to the illness, preventing at present the abuse of antibiotics and causing drug tolerant bacteria etc. to have great meaning and value aspect stretching rapidly, also can be used as critical patient and slow down complementary tool and the facility of symptom when handling and use.

Below in conjunction with the specific embodiment, foregoing of the present utility model is described in further detail again by the accompanying drawing illustrated embodiment.But this should be interpreted as that the scope of the above-mentioned theme of the utility model only limits to following example.Do not breaking away under the above-mentioned technological thought situation of the utility model, various replacements or change according to ordinary skill knowledge and customary means are made all should be included in the scope of the present utility model.

Description of drawings

Fig. 1 is a kind of structural representation that the utility model is used for collecting the filter of blood source of infection class material.

The specific embodiment

The utility model as shown in the figure is used for collecting the filter of blood source of infection class material, in the housing 5 formed content cavity of the both sides flexible material that the periphery 3 by fusion structure 2 forms seals, be gripped with by through the stacked filter cartridge construction that forms 4 of lamellar fibre material of ungrease treatment, and the periphery of filter cartridge construction 4 also fuses and is locked in the periphery 3 that is formed by fusion structure 2.The pore size filter of filter cartridge construction 4 is the 15-80 micron, is good with the 25-80 micron especially.The flexible material of housing 5 can be medical PVC, ABS material, makrolon material, and these materials is material modified, or as masking foil material, PE material etc.Respectively be provided with a catheter 1 that can be communicated with inside and outside its content cavity on two side bodies 5, the internal orifice of catheter 1 lays respectively at the both sides that filter cartridge construction 4 filters paths.Also can further be provided with removable connecting elements 6 such as easy-to-mount spiral interconnection system female Luer on the catheter 1.The shape of filter can adopt as circle, ellipse etc. multiple by closed curve around the shape that forms, or as rhombus, rectangle, square, triangle, multiple rectilinear polygon or the polygonal shape of fillet such as trapezoidal.

Claims

1. be used for collecting the filter of blood source of infection class material, in the content cavity that two side bodies (5) by periphery (3) sealing form, be gripped with filter cartridge construction (4), the periphery of filter cartridge construction (4) also with the sealing mutually of the periphery (3) of housing, on two side bodies (5), respectively be provided with one and can be communicated with the inside and outside catheter (1) of its content cavity, the internal orifice of catheter (1) lays respectively at the both sides that filter cartridge construction (4) filters path, and the pore size filter that it is characterized in that filter cartridge construction (4) is greater than 15 microns.

2. the filter that is used for collecting blood source of infection class material as claimed in claim 1, the pore size filter that it is characterized in that filter cartridge construction (4) is the 15-80 micron.

3. the filter that is used for collecting blood source of infection class material as claimed in claim 1 is characterized in that said filter cartridge construction (4) is served as reasons to form through the lamellar fibre material of ungrease treatment is stacked.

4. as the described filter that is used for collecting blood source of infection class material of one of claim 1 to 3, it is characterized in that said two side bodies (5) are the form of flexible material.

5. as the described filter that is used for collecting blood source of infection class material of one of claim 1 to 3, it is characterized in that said catheter (1) is provided with removable jointing (6).