CN1879901A - Multifunctional easily-transportable artificial kidney - Google Patents
Multifunctional easily-transportable artificial kidney Download PDFInfo
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- CN1879901A CN1879901A CNA2006100708097A CN200610070809A CN1879901A CN 1879901 A CN1879901 A CN 1879901A CN A2006100708097 A CNA2006100708097 A CN A2006100708097A CN 200610070809 A CN200610070809 A CN 200610070809A CN 1879901 A CN1879901 A CN 1879901A
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Abstract
The invention relates to a multifunctional portable artificial kidney, which is used to treat acute renal failure,etc, as one blood purify device. And the invention can process general blood dialysis, blood plasma replace, CRRT and filtration. The invention simplifies the dialysis liquid feeding system, to accurately control the capacity, without acetate dialysis and depending on water source. The invention is formed by an external blood cycle detecting system, a dialysis liquid cycle detecting system and a replace liquid and blood plasma feeding system. The invention has simple production and wide application.
Description
The present invention relates to a kind of armarium, particularly a kind of multifunctional easily-transportable artificial kidney.The present invention is fit to medical institutions at different levels and is used to give treatment to acute renal failure, chronic renal failure, each phase uremia, multiple organ dysfunction syndrome companion renal failure, severe pancreatitis, be fit to continue the various diseases of kidney alternative medicine (CRRT) treatment, poisonous substance, drug intoxication etc.
The conventional artificial kidney machine (haemodialysis control unit) of existing background technology is used to give treatment to acute renal failure at large, chronic renal failure, each phase uremia, and design is fairly perfect, large-scale haemodialysis control unit designs general computerization, capacity monitor, basic functions such as hydrocarbonate dialysis all possess.But, the ubiquitous shortcoming of conventional artificial kidney machine is: [1] relies on the water source, conventional hemodialysis (CHD) machine or hemodialysis filter must be by reverse osmosis water treatment machines in treatment, continuously reverse osmosis water is delivered to haemodialysis control unit by high-pressure water pipe, automatic mixing system by haemodialysis control unit, A, B concentrated solution are mixed with and can carry out the treatment of hemodialysis or hemodiafiltration through the dialysis solution of blood dialyser or transfusion filters with reverse osmosis water pari passu.[2] can not move temporarily, conventional artificial kidney machine is large-scale haemodialysis control unit or hemodialysis filter, owing to rely on the water source, be unable to do without the reverse osmosis water blood processor, so be unable to do without Blood Purification Center or Laminar Airflow Room in the treatment, can not move that patient's bed is other to carry out hemodialysis or hemodiafiltration treatment according to patient's the state of an illness.[3] can not carry out the other CRRT treatment of bed, the other CRRT content of bed comprises: continuous arterio venous hemofiltration (CAVH), continuously silently-venous hemofiltration (CVVH), continuous arterio venous hemofiltration dialysis (CAVHD), vein-venous hemofiltration dialysis (CVVHD) continuously, continuously slow hemofiltration (CSHF), continuously slow blood ultrafiltration (CSHU).These contents of CRRT treatment are because the inconvenience of conventional hemodialysis (CHD) machine is moved and all is difficult to carry out.[4] can not carry the rescue of paying a home visit, because the conventional hemodialysis (CHD) machine relies on the water source, can not carry the treatment patient that pays a home visit according to emergency arbitrarily, the section office that can not be in hospital as required haemodialysis control unit be moved the patient place carry out emergency aid and treatment.[5] can not carry out plasmapheresis, no matter which kind of type of conventional hemodialysis (CHD) machine has only one or two blood pump, present design all can not be carried out the membrane type blood plasma replacement therapy.[6] manufacturing cost height, the conventional hemodialysis (CHD) machine is an automatic mixing pump formula owing to the dialysis solution dosing, the capacity monitor balance cavity type, its electronics, Machine Design are all very complicated, cause the manufacturing cost height, and selling price is difficult to drop to lower level.[7] waste water resource, the water source that first conventional hemodialysis (CHD) machine is used after all being handled by the reverse osmosis water blood processor, when the reverse osmosis water blood processor is used tap water in the processing city, will have the tap water of a great deal of to be dumped simultaneously; It two is the used dialysis solution of conventional hemodialysis (CHD) machine, promptly drained into sewer by dialyser or filter once to drain, to use the water source when before treating, preparing, per minute is 500 milliliters behind every haemodialysis control unit begin treatment, per hour 30,000 milliliters, treatment time was generally 4～5 hours, that is to say that each treatment wants water 12～150,000 milliliter dialysis solution; Add that the water that equal quantities dumps from water treatment facilities promptly reaches 24～300,000 ml waters.For the per capita like this water resources quantity of China is very disadvantageous for world occupancy volume per person's 1/6 national state only.[8] capacity ultrafiltration error higher, the current import conventional hemodialysis (CHD) machine of probability that is out of order more greatly adopts the two chamber system of capacitance balance mostly.Because two chamber balance sysmtes are controlled with the form of electric mechanical automatically by 8 electronics valves, as long as there is an electronics machine valve to be out of order, automatically capacity control system just can accurately not controlled capacitance balance, so volume control just can not be very accurate, and out of order chance is higher.Following table compares a kind of medical multifunctional portable artificial kidney and conventional hemodialysis (CHD) machine and existing C RRT machine work one.
Table: a kind of multifunctional easily-transportable artificial kidney and conventional hemodialysis (CHD) machine and existing CRRT machine compare:
| Item compared | Portable artificial kidney | The conventional hemodialysis (CHD) machine | The CRRT machine |
| 1, conventional kidney alternative medicine | Energy (energy savings) | Energy | Can not, consume too big |
| 2, hydrocarbonate dialysis | Energy | Energy (medium and high-grade machine) | Energy |
| 3, high-sodium dialysis | Energy | Energy (medium and high-grade machine) | Energy |
| 4, treat water consumption at every turn | 3～40,000 | 24～300,000 milliliters | 3.6～5.0 ten thousand milliliters |
| 5, low sodium dialysis | Energy | Energy (medium and high-grade machine) | |
| 6, alternately dialysis of height sodium | Energy | Energy (medium and high-grade machine) | |
| 7, sodium lactate dialysis | Energy | Can not | Can not |
| 8, capacity monitor | Energy | Energy (medium and high-grade machine) | |
| 9, pairing hemodiafiltration | Energy | Energy (special-purpose high-grade machine) | Can not |
| 10, to the water source requirement | Do not rely on the water source | Rely on the water source | Do not rely on the |
| 11, plasmapheresis | Energy | Can not | Energy |
| 12, the other hemodialysis of bed | Energy | Can not | Energy |
| 13, bedside hemodialysis filtration | Energy | Can not | Energy |
| 14, the other CAVHD of bed | Energy | Can not | Energy |
| 15, the other CVVHD of bed | Energy | Can not | Energy |
| 16, the rescue of paying a home visit | Energy | Can not | Can not |
| 17, manufacturing cost | Low | High | High |
| 18, the dialysis solution pipeline is once used | Can, cost is low | Can not | Energy, |
| 19, dialysis solution is the pulse push-and-pull | Be | Be not | Be not |
| 20, save dialysis dry powder | 50～100%/once | Can not | Can not |
| 21, no acetic acid dialysis | Energy, simple | Can not/realize complicated | Energy, cost height |
Purpose of the present invention, a kind of multifunctional easily-transportable artificial kidney (multi-functional removable haemodialysis control unit) that designs at above-mentioned deficiency exactly.Multi-functional removable haemodialysis control unit has been simplified the dialysis solution feed system of conventional hemodialysis (CHD) machine widely.Do not rely on the water source, not given treatment to the place limits, conserve water resource and dialysis dry powder, can be temporarily pass that patient's bed is other to carry out interim emergency aid and treatment, also can be used for paying a home visit and rescue etc., in short according to patient's treatment needs, the work that the conventional hemodialysis (CHD) function is carried out, multifunctional easily-transportable artificial kidney all can carry out, and the work that the conventional hemodialysis (CHD) machine can not carry out, multifunctional easily-transportable artificial kidney still can carry out.Multifunctional easily-transportable artificial kidney conserve water resource, to our the insufficient country of such water resource, especially the water shortage in north china area seems even more important.The dialysis solution system of portable artificial kidney carries out in fully effectively scope internal recycle repeated use, does not have the problem that affects the treatment.As the practical situation of pressing portable artificial kidney is calculated, 40,000 milliliters of each conventional hemodialysis (CHD) treatment practical application dialysis solution, recycle 3～4 (40,000 milliliters * 3～4 times) actual exchange dialysis liquid measures and be 9～12 or 12～160,000 milliliters, (when using for the first time is fresh dialysis solution, have only second be only repeated use) to using for the third time.If blood flow reaches per minute 150～250ml, on curative effect, will not be lower than the conventional hemodialysis (CHD) machine, because the primary condition of treatment is all identical, even be higher than the conventional hemodialysis (CHD) machine.Because two dialysis solution circulating pumps that multifunctional easily-transportable artificial kidney dialysis solution blood circulation adopts, because flowing, dialysis solution is the pulse wave, semipermeable membrane to dialyser has certain push-and-pull action, thus can improve the permeability of semipermeable membrane, thus improve dialytic efficiency.As seen from the table, multi-functional removable haemodialysis control unit is compared with existing C RRT machine, shows that equally the removable haemodialysis control unit has absolute strong point, is that the CRRT machine is not available, and the strong point of removable haemodialysis control unit, the CRRT machine is not accomplished.Also there is the shortcoming of self in existing C RRT machine compared with multifunctional easily-transportable artificial kidney.So, the patient that can make numerous needs obtain the blood purification treatment can both obtain treatment.Thereby improve the situation that still has numerous medical institutions, especially county, district's level medical institutions to hang back at present in the face of expensive conventional hemodialysis (CHD) machine.Portable artificial kidney can carry out multiple medical scheme, is the automatically working process substantially.The work efficiency that improves single doctor, protects personnel.The present invention is fit to emergency department's first aid, Urology Department Laminar Airflow Room (center) conventional therapy and the first aid of all big-and-middle-sized medical institutions, ICU chamber emergency treatment, contagious department emergency treatment patient's first aid, Department of B urn first aid; Especially be fit to basic medical unit, Army Hospital, individual blood purifies specialist clinic and uses.Have large-scale application prospect, substantive contribution is made in the development of China's blood purification cause.
The present invention realizes like this, multifunctional easily-transportable artificial kidney, it is characterized in that: A. is connected with dialysis solution circulation pipe (3a) by dialysis solution fairlead (2) by the first dialysis solution circulating pump (1), dialysis solution circulation pipe (3a) is connected with the dialysate hole (4a) of dialyser or filter (5-1), the dialysate hole (4a) of dialyser or filter (5-1) is the part of dialyser or filter (5), the dialysate hole (4b) of dialyser or filter (5) also is that the part of dialyser or filter (5-1) is connected with dialysis solution circulation pipe (3b), dialysis solution circulation pipe (3b) is connected with the second dialysis solution circulating pump (6), by being connected with dialysis fluid container (8) with dialysis solution inlet tube (7), dialysis fluid container (8) places the weighing platform to heat on the Heng Wenban (9), dialysis fluid container temperature measurer probe or liquid temperature table (10) insert in the dialysis fluid container (8), the cable that temperature is preset display (11) and the weighing platform Heng Wenban (9) that heats links to each other with computer and display screen (42), predetermined, regulate weighing platform heat temperature and the ultrafiltration monitoring of Heng Wenban (9), constitute the dialysis solution circulation of multifunctional easily-transportable artificial kidney, heat, the weighing apparatus temperature, the capacity monitor system, as shown in Figure 1;
B. be connected with the form of partly spiraling in pump case with blood pump (13) by ductus arteriosus (12), bubble trap (14) is arranged on the ductus arteriosus (12), exhaustor (15) is arranged on bubble trap (14), ductus arteriosus (12) is connected with the arterial end (16) of dialyser or filter (5), the other end of dialyser or filter (5) is connected with venous duct (17), bubble trap (18) is arranged on the venous duct (17), coupled exhaustor (19) and venous pressure monitoring pipe (20) are arranged on bubble trap (18), venous duct (17) bubble trap (18) venous duct (17) afterwards continues to prolong, partly spiral and be connected with flow plug or automatic electric folder (21), venous duct (17) presss from both sides (21) afterwards by flow plug or automatic electric, be connected with patient's internal fistula puncture needle tail pipe or two-chamber large vein puncture tube on one's body, constitute the extracorporeal blood circulation system of multifunctional easily-transportable artificial kidney, as shown in Figure 2;
C. be connected with displacement liquid hook (23) by weight sensor (22-1), displacement liquid hook (23) and displacement liquid or blood plasma or plasma substitute container (24) are connected, displacement liquid or blood plasma or plasma substitute container (24) are connected with transfusion catheter (25), tube for transfusion (25) and displacement liquid or blood plasma or plasma substitute infusion pump (26) are connected, transfusion catheter (25) partly spirals by behind displacement liquid or blood plasma or the plasma substitute infusion pump (26), be connected with ductus arteriosus (12), constitute the preceding dilution method fluid infusion system of the continuous kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney, as shown in Figure 3;
D. transfusion catheter (25) partly spirals and is connected by displacement liquid or blood plasma or plasma substitute infusion pump (26) back and the exhaustor (19) on the venous duct bubble trap (18), promptly constitute the back dilution method fluid infusion system of the continuous kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney, as shown in Figure 4;
E. be connected in the mode of placing by weight monitoring platform (27) and displacement liquid or blood plasma or plasma substitute tun (28), the transfusion catheter (29) that displacement liquid or blood plasma or plasma substitute tun (28) and displacement liquid or blood plasma or plasma substitute tun are connected is connected, transfusion catheter (29) continuity that displacement liquid or blood plasma or plasma substitute tun are connected forward, partly spiral and be connected with ductus arteriosus (12) by displacement liquid or blood plasma or plasma substitute infusion pump (26), constitute the another kind of preceding dilution method fluid infusion system of the continuous kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney, as shown in Figure 5;
F. transfusion catheter (29) continuity that is connected by displacement liquid or blood plasma or plasma substitute tun forward, the exhaustor (19) that links to each other by displacement liquid or blood plasma or plasma substitute infusion pump (26) back and the bubble trap (18) on the venous duct (17) that partly spirals is connected, constitute the another kind of back dilution method fluid infusion system of the continuous kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney, as shown in Figure 6;
G. link by connecting tube (30) one ends and dialyser or filter (5), the arterial end of the other end and perfusion device (31) links, the vein end of perfusion device (31) and venous duct (17) link, and promptly constitute the structure of hemodialysis perfusion system, as shown in Figure 7;
H. be connected with blood drainage pipe (33) by disposable Membrane Plasma Separator (32), blood plasma drainage tube (33) inserts in the blood plasma drainage container (34), there is exhaustor (35) to insert in the blood plasma drainage container (34) simultaneously, blood plasma drainage container (34) places the weighing platform to heat on the Heng Wenban (9), displacement liquid or blood plasma or plasma substitute container (24) hang on the displacement liquid hook (23), one end of transfusion catheter (25) and displacement liquid or blood plasma or plasma substitute container (24) are connected, the other end partly spirals and is connected by displacement liquid or blood plasma or plasma substitute infusion pump (26) back and the exhaustor (19) on the venous duct bubble trap (18), constitute disposable blood plasma and separate the replacement therapy hardware system, as shown in Figure 8;
I. partly spiral by ductus arteriosus (12) and be connected with blood pump (13), by being connected with disposable Membrane Plasma Separator (32) again behind the blood pump (13), the blood plasma tap of disposable Membrane Plasma Separator (32) lower end is connected with blood plasma drainage tube (33), blood plasma drainage tube (33) continues and is connected with blood plasma thermostat (36) forward, behind blood plasma thermostat (36), partly spiral and be connected with separator of blood plasma components (37) by displacement liquid or blood plasma or plasma substitute infusion pump (26), the healthy blood plasma of separating through separator of blood plasma components feeds back pipe (39) by blood plasma and is connected with exhaustor (19) and can feeds back healthy blood plasma, the cause of disease blood plasma of separating from separator of blood plasma components (37) that has has cause of disease blood plasma to dump pipe (38) to be connected with discarded blood plasma container (34) and can to have dumped cause of disease blood plasma by what be connected with separator of blood plasma components (37), constitute dual blood plasma components and separate the system hardware system that feeds back, as shown in Figure 9;
J. linked with anticoagulant infusion tube (41) by anticoagulant syringe pump and anticoagulant syringe (40), anticoagulant infusion tube (41) links with ductus arteriosus (12), constitutes anticoagulant and keeps adding system, shown in Fig. 2～11;
K. partly spiral by the pump line section of ductus arteriosus (12) and be connected with blood pump (13), be connected with disposable blood plasma separator (32) more afterwards, the vein end of plasma separator (32) is connected with venous duct (17), bubble trap (18) is arranged on the venous duct (17), venous duct (17) is connected with patient's puncture needle tail pipe or conduit on one's body after continuity is by flow plug or automatic electric folder (21); Displacement liquid or blood plasma or plasma substitute container (24) are connected with transfusion catheter (25), the second dialysis solution circulating pump (6) as displacement liquid or blood plasma or plasma substitute infusion pump, transfusion catheter (25) partly spirals by being connected as the approach of transfusion or plasma transfusion or blood plasma substitute as the second dialysis solution circulating pump (6) of displacement liquid or blood plasma or plasma substitute infusion pump exhaustor (19) back and on the bubble trap, constitute the metathetical hardware system of another disposable blood plasma, as shown in figure 10;
L. partly spiral by the pump line section of ductus arteriosus (12) and link with blood pump (13), detour afterwards by blood pump (13), be connected with the arterial end of a Membrane Plasma Separator (32), the vein end of a Membrane Plasma Separator (32) is connected with venous duct (17), bubble trap (18) is arranged on the venous duct (17), venous duct (17) is after continuity is by flow plug or automatic electric folder (21), join with patient's puncture needle tail pipe or double lumen tube on one's body, the blood plasma of separating from a Membrane Plasma Separator (32), partly spiral by blood plasma drainage tube (33) and to walk around the first dialysis solution circulating pump (1) and be connected with the blood plasma upstream end of separator of blood plasma components (37), cause of disease blood plasma is arranged and have cause of disease blood plasma to dump pipe (38) to be connected from what come out from separator of blood plasma components branch (37), having cause of disease blood plasma to dump pipe (38) is connected with discarded plasma collection container (34), the anosis blood plasma of separating from separator of blood plasma components (37), feeding back the exhaustor (19) that pipe (39) links to each other with bubble trap (18) on the venous duct (17) by the blood plasma that is connected with separator of blood plasma components (37) is connected, displacement liquid or blood plasma or plasma substitute container (24) are connected with transfusion catheter (25), the second dialysis solution circulating pump (6) as displacement liquid or blood plasma or plasma substitute infusion pump, transfusion catheter (25) partly spirals by being connected as the approach of transfusion or plasma transfusion or blood plasma substitute as the second dialysis solution circulating pump (6) of displacement liquid or blood plasma or plasma substitute infusion pump exhaustor (19) back and on the bubble trap, constitute the metathetical hardware system of another dual separating plasma, as shown in figure 11.
M. partly spiral by the pump line section of ductus arteriosus (12) and be connected with blood pump (13), partly spiral and detour afterwards by blood pump (13), be connected with ductus arteriosus bubble trap (14), exhaustor (15) is arranged on the bubble trap (14), ductus arteriosus (12) continues continuity forward, be connected with the arterial end (16) of paired filtration dialysis device (5-2), the vein end of paired filtration dialysis device (5-2) is connected with venous duct (17), exhaustor (19) and vein pressure pipe (20) are arranged on the bubble trap (18) on the venous duct (17), venous duct (17) continues forward, detour and press from both sides (21) afterwards by flow plug or automatic electric, be connected with patient's internal fistula puncture needle tail pipe or two-chamber large vein puncture tube on one's body, constitute the extracorporeal blood circulation system of multifunctional easily-transportable artificial kidney pairing dialysis filtration system, the filtered solution of discharging by the filtered solution tap (4c) of paired filtration dialysis device (5-2), by filtered solution collecting pipe (4d) drain to filtered solution collecting bag (4e), filtered solution collecting bag (4e) hangs on the weight sensor (22-2), weight sensor (22-2) is connected with cable with computer and display (42), collect, calculate and show and filter liquid measure, and the rotating speed of feedback regulation displacement liquid or blood plasma or plasma substitute infusion pump (26), carry out dynamic infusion on demand, as shown in figure 12.
The multi-functional artificial kidney that just moves of the present invention can also be to realize like this, its feature also is: the dialysis solution circulation of A. multifunctional easily-transportable artificial kidney, heat, the weighing apparatus temperature, the working procedure of capacity monitor system is: A-1 places dialysis fluid container (8) the weighing platform to heat on the Heng Wenban (9), dialysis solution fairlead (2) and dialysis solution inlet tube (7) are inserted respectively in the dialysis fluid container (8), start the first dialysis solution circulating pump (1) and the second dialysis solution circulating pump (6), dialysis solution is sent to the dialysate hole (4a) of dialyser or filter (5-1) through dialysis solution circulation pipe (3a), dialysis solution arrives its other end dialysate hole (4b) through dialyser or filter (5-1), through dialysis solution circulation pipe (3b), by the second dialysis solution circulating pump (6), dialysis solution is introduced in the dialysis fluid container (8) through dialysis solution inlet tube (7); A-2 ultrafiltration program is: according to the ultrafiltration volume that presets, automatically adjust the second dialysis liquid pump (6) by computer and display (42) and realize ultrafiltration with the speed discrepancy of the first dialysis liquid pump (1), adopt a gram to be the weight sensor of unit, realization is to transmembrane pressure (Trans-membrane pressure, TMP) dynamic adjustment, thereby the ultrafiltration volume in unit of adjustment's time, by the weighing platform Heng Wenban (9) that heats alleged weight is continuously fed back to computer (42), dynamically revise ultrafiltration volume, until the amount of setting that reaches in the unit interval, go up pressurization or decompression maloperation at dialysis fluid container (8) unexpectedly as if occurring in treatment, setting is ignored program and is got rid of interference; The heat program of weighing apparatus temperature of A-3 is: according to indoor environment temperature, set in advance the temperature of the Heng Wenban that heats (9), and be presented on default display (11) of temperature and the machine calculation machine screen (42), by the Heng Wenban that heats (9) the temperature indirect transfer in the dialysis fluid container (8), reach control, the temperature of (8) the middle dialysis solution of keeping dialysis fluid container; B. the working procedure of the fluid infusion of multifunctional easily-transportable artificial kidney, transfusion, plasma transfusion or blood plasma substitute is: B-1 hangs on displacement liquid or blood plasma or blood plasma substitute (24) on the displacement liquid hook (23), one end of transfusion catheter (25) and displacement liquid or blood plasma or blood plasma substitute (24) are connected mutually, the other end is connected with transfusion short tube on the ductus arteriosus (12), or be connected for the exhaustor (19) on the bubble trap of one (18) with venous duct (17), dilution or back dilution method fluid infusion perhaps replenish blood plasma, blood plasma substitute etc. before carrying out; B-2 is positioned over displacement liquid or blood plasma or plasma substitute tun (28) on the weight monitoring platform (27), displacement liquid or blood plasma or plasma substitute tun (28) are connected with transfusion catheter (29), transfusion catheter (29) continuity forward, partly spiraling is connected with ductus arteriosus (12) by displacement liquid or blood plasma or plasma substitute infusion pump (26), constitutes dilution method fluid infusion system before continuous kidney alternative medicine (CRRT) another kind of of multifunctional easily-transportable artificial kidney; B-3 is positioned over displacement liquid or blood plasma or plasma substitute tun (28) on the weight monitoring platform (27), the connection tube of displacement liquid or blood plasma or plasma substitute tun (28) is connected mutually with transfusion catheter (29), transfusion catheter (29) continuity forward, partly spiral by displacement liquid or blood plasma or plasma substitute infusion pump (26) back and venous duct (17) to the exhaustor (19) on the bubble trap of one (18) is connected, carry out back dilution method fluid infusion, plasma transfusion etc.
The multi-functional artificial kidney that just moves of the present invention can also be to realize like this, its feature also is: the software work program of multifunctional easily-transportable artificial kidney is: after computer and control panel (42) startup is started working, promptly being in stress duty, heat after platform (9) goes up when dialysis fluid container (8) being positioned over weigh, computer promptly weighs up the weight of dialysis fluid container (8), behind the beginning dialysis treatment, the first dialysis solution circulating pump (1) starts, by dialysis liquid pump fairlead (2) dialysis solution is drawn, through dialyser or filter (5-1), taken out to draw by the second dialysis solution circulating pump (6) and send dialysis fluid container (8) back to, when needs increase ultrafiltration, the second dialysis solution circulating pump (6) is according to computing information value speedup, and when needs reduced ultrafiltration, the second dialysis solution circulating pump (6) slowed down according to the computing information value; When accident weighing heat increase on the platform (9), during the loss of weight amount, the program of ignoring of design is promptly given and being ignored; The dialysis solution of drawing from the first dialysis solution circulating pump (1) causes conductivity sensor and joins with computer according to conduit, with the conductivity of prompting dialysis solution; Actual temperature according to dialysis solution is as the criterion, and sets the temperature of dialysis solution, and when dialysate temperature is lower than the physiological need temperature, the platform (9) of heating of weighing is promptly opened and heated; When dialysate temperature reaches required physiological temp, the platform (9) of heating of weighing promptly stops to heat; Behind the dialysis treatment result, the time of setting sterilization dialysis solution circulation pipe is 0～60 minute, arrives when the disinfectant time, and the first dialysis solution circulating pump (1) and the second dialysis solution circulating pump (6) promptly stop automatically; When carrying out the cleaning of dialysis solution circulation pipe sterilization back, adorn 5000～10000ml reverse osmosis water or aquae destillata with dialysis fluid container (8), dialysis liquid pump fairlead (2) is inserted in reverse osmosis water or the aquae destillata, dialysis solution inlet tube (7) is inserted in another dialysis fluid container, start dialysis liquid pump (1) and (6), make reverse osmosis water or aquae destillata flow into another dialysis fluid container from dialysis fluid container (8), when the cleanout fluid in the dialysis fluid container (8) (reverse osmosis water or aquae destillata) weight during greater than 200g (200ml), cleaning is proceeded, when cleanout fluid weight during less than 200g (200ml), hemo system i.e. shutdown automatically, as shown in figure 13.
Below in conjunction with accompanying drawing the present invention is further described:
1-among Fig. 1 is the first dialysis solution circulating pump, 2-dialysis liquid pump fairlead partly spirals by the 1-first dialysis solution circulating pump, be connected with 3a-dialysis solution circulation pipe, 3a-dialysis solution circulation pipe is connected with the dialysate hole of 4a-dialyser or filter (5-1), the 4b-dialysate hole also is the part of dialyser or filter (5-1), the 4b-dialysate hole is connected with 3b-dialysis solution circulation pipe, 3b-dialysis solution circulation pipe partly spirals and is connected with 7-dialysis solution inlet tube by the 6-second dialysis solution circulating pump, the 8-dialysis fluid container place 9-weighing platform heat the weighing apparatus warm plate on, 10-dialysis fluid container temperature measurer probe or liquid temperature table insert in the dialysis fluid container (8), default its cable of display of 11-temperature and the weighing platform Heng Wenban (9) that heats is connected with computer and display screen (42), and the dialysis solution of formation multifunctional easily-transportable artificial kidney circulates, heat, the weighing apparatus temperature, the capacity monitoring, the capacity monitor system;
12-among Fig. 2 is a ductus arteriosus, be connected with the form of spiraling in pump case with the 13-blood pump, 14-ductus arteriosus bubble trap and 12-ductus arteriosus are one, 15-ductus arteriosus exhaustor is connected with the 14-bubble trap, the arterial end of 16-dialyser or filter (5) is connected with the 12-ductus arteriosus, the 17-venous duct is connected with the other end of 5-dialyser or filter, 18-venous duct bubble trap is the part on the 17-venous duct, 19-venous duct exhaustor is connected with 18-venous duct bubble trap with 20-venous pressure monitoring pipe, 21-flow plug or automatic electric folder, after the 17-venous duct partly spirals and walks around 21-flow plug or automatic electric folder, be connected with patient's internal fistula backshank pipe or two-chamber hemodialysis pipe on one's body, constitute the blood circulation of multifunctional easily-transportable artificial kidney;
22-1-among Fig. 3 is that weight sensor is connected with 23-displacement liquid hook, 23-displacement liquid hook and 24-displacement liquid or blood plasma or plasma substitute container are connected, 24-displacement liquid or blood plasma or plasma substitute container are connected with the 25-transfusion catheter, 25-transfusion catheter and 26-displacement liquid or blood plasma or plasma substitute infusion pump hover above in the pump case with the form of spiraling partly and are connected, after the 25-transfusion catheter passes through 26-displacement liquid or blood plasma or plasma substitute infusion pump, be connected with the 12-ductus arteriosus, constitute the preceding dilution method fluid infusion system of the continuous kidney alternative medicine of multifunctional easily-transportable artificial kidney (CRRT);
25-among Fig. 4 is that transfusion catheter partly spirals and walks around 26-displacement liquid or blood plasma or plasma substitute infusion pump, 19-exhaustor on the 18-venous duct bubble trap is connected, and constitutes the back dilution method fluid infusion system of the lasting kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney;
27-among Fig. 5 is the weight monitoring platform, be connected in the mode of placing with 28-displacement liquid or blood plasma or plasma substitute tun, the transfusion catheter that 28-displacement liquid or blood plasma or plasma substitute tun and 29-displacement liquid or blood plasma or plasma substitute tun are connected is connected, the transfusion catheter continuity that 29-displacement liquid or blood plasma or plasma substitute tun are connected forward, partly spiral and walk around 26-displacement liquid or blood plasma or plasma substitute infusion pump, be connected with the 12-ductus arteriosus, constitute the another kind of preceding dilution method fluid infusion system of the lasting kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney;
The transfusion catheter that 29-displacement liquid among Fig. 6 or blood plasma or plasma substitute tun are connected, partly spiral by behind 26-displacement liquid or blood plasma or the plasma substitute infusion pump, with 17-venous duct and 18-bubble trap is that 19 exhaustors on the one are connected, and constitutes the another kind of back dilution method fluid infusion system of the lasting kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney;
30-connecting tube one end among Fig. 7 and 5-dialyser or filter link, and the arterial end of the other end and 31-perfusion device links, and the vein end and the 17-venous duct of 31-perfusion device link, and promptly constitute the system hardware architecture of hemodialysis perfusion system;
Fig. 8-in the disposable Membrane Plasma Separator of 32-be connected with 33-blood plasma drainage tube, 33-blood plasma drainage tube inserts in the 34-blood plasma drainage container, there is the 35-exhaustor to insert in the 34-blood plasma drainage container simultaneously, 34-blood plasma drainage container place the 9-weighing platform heat the weighing apparatus warm plate on, 24-displacement liquid or blood plasma or plasma substitute container hang on the 23-displacement liquid hook, one end of 25-transfusion catheter and 24-displacement liquid or blood plasma or plasma substitute container are connected, the other end spirals by behind 26-displacement liquid or blood plasma or the plasma substitute infusion pump, be connected with the 19-exhaustor on the 18-venous duct bubble trap, constitute disposable membrane type blood plasma and separate the replacement therapy hardware system;
Fig. 9-in the 12-ductus arteriosus partly spiral and be connected with the 13-blood pump, behind the 13-blood pump, be connected with the disposable Membrane Plasma Separator of 32-again, the blood plasma tap of the disposable Membrane Plasma Separator of 32-lower end is connected with 33-blood plasma drainage tube, 33-blood plasma drainage tube continues and is connected with 36-blood plasma thermostat forward, behind 36-blood plasma thermostat, partly spiral by 26-displacement liquid or blood plasma or plasma substitute infusion pump, be connected with the 37-separator of blood plasma components, the healthy blood plasma of separating through the 37-separator of blood plasma components is connected with the 19-exhaustor by 39-blood plasma feedback pipe, can feed back healthy blood plasma, from what the 37-separator of blood plasma components was separated cause of disease blood plasma arranged, having cause of disease blood plasma to dump pipe by the 38-that links to each other with the 37-separator of blood plasma components is connected with the discarded blood plasma container of 34-, the 35-exhaustor inserts in the discarded blood plasma container of 34-, can dump cause of disease blood plasma, constitute dual blood plasma components and separate the feedback system;
40-anticoagulant syringe pump in Fig. 2～12 and anticoagulant syringe and 41-anticoagulant infusion tube link, and 41-anticoagulant infusion tube and 12-ductus arteriosus link, and constitute anticoagulant and keep adding system;
The pump case inwall that the pump line section of the 12-ductus arteriosus among Figure 10 is partly spiraled with the 13-blood pump links, be connected with the disposable blood plasma separator of 32-more afterwards, the vein end of the disposable blood plasma separator of 32-is connected with the 17-venous duct, the 18-bubble trap is arranged on the 17-venous duct, the 17-venous duct continues continuity by after 21-flow plug or the electrical clip, is connected with patient's puncture needle tail pipe or conduit on one's body; 24-displacement liquid or blood plasma or plasma substitute container are connected with the 25-transfusion catheter, the 6-second dialysis solution circulating pump as displacement liquid or blood plasma infusion pump, the 25-transfusion catheter partly spirals by behind the 6-second dialysis solution circulating pump as displacement liquid or blood plasma or plasma substitute infusion pump, be connected with the exhaustor on the 19-bubble trap, as the approach of transfusion or plasma transfusion or blood plasma substitute; The blood plasma tap of the disposable blood plasma separator of 32-is connected with 33-blood plasma drainage tube, 33-blood plasma drainage tube has the cause of disease plasma collection container to be connected with 34-, have on the cause of disease plasma collection container at 34-, the 35-exhaustor is arranged, constitute the metathetical hardware system of another disposable blood plasma;
The pump line section of the 12-ductus arteriosus among Figure 11 is partly spiraled and the 13-blood pump links, detour by after the 13-blood pump, be connected with the arterial end of the disposable Membrane Plasma Separator of 32-, the vein end of the disposable Membrane Plasma Separator of 32-is connected with the 17-venous duct, the 18-bubble trap is arranged on the 17-venous duct, the 17-venous duct continues continuity by after 21-flow plug or the automatic electric folder, join with patient's puncture needle tail pipe or double lumen tube on one's body, the blood plasma of separating from the disposable Membrane Plasma Separator of 32-, partly spiral by the 1-first dialysis solution circulating pump by 33-blood plasma drainage tube, be connected with the blood plasma upstream end of 37-separator of blood plasma components, have cause of disease blood plasma and 38-to have cause of disease blood plasma to dump pipe to be connected from what the 37-separator of blood plasma components was separated, 38-has cause of disease blood plasma to dump pipe to discard plasma collection container with 34-and be connected, the no cause of disease blood plasma of separating from the 37-separator of blood plasma components, feeding back the 19-exhaustor that pipe links to each other with 18-bubble trap on the 17-venous duct by the 39-blood plasma that links to each other with the 37-separator of blood plasma components is connected, 24-displacement liquid or blood plasma or plasma substitute container are connected with the 25-transfusion catheter, the 6-second dialysis solution circulating pump as displacement liquid or blood plasma or plasma substitute infusion pump, the 25-transfusion catheter partly spirals by behind the 6-second dialysis solution circulating pump as displacement liquid or blood plasma or plasma substitute infusion pump, be connected with the 19-exhaustor on the 18-bubble trap, as the approach of transfusion or plasma transfusion or blood plasma substitute, constitute the metathetical hardware system of another dual separating plasma.
The pump line section of the 12-ductus arteriosus among Figure 12 is partly spiraled and is connected with the 13-blood pump, partly spiral and walk around after the 13-blood pump, be connected with 14-ductus arteriosus bubble trap, on the 14-ductus arteriosus bubble trap 15-exhaustor is arranged, the 12-ductus arteriosus continues forward, be connected with the 16-arterial end of 5-2-paired filtration dialysis device, the vein end of 5-2-paired filtration dialysis device is connected with the 17-venous duct, 18-bubble trap and 19-exhaustor and 20-vein pressure pipe are arranged on the 17-venous duct, the 17-venous duct continues forward, detour by after 21-flow plug or the automatic electric folder, be connected with patient's internal fistula puncture needle tail pipe or two-chamber large vein puncture tube on one's body, constitute the extracorporeal blood circulation system of multifunctional easily-transportable artificial kidney paired filtration dialysis system, the filtered solution of discharging by the 4c-filtered solution tap of 5-2-paired filtration dialysis device, by the drain of 4d-filtered solution collecting pipe to 4e-filtered solution collecting bag, 4e-filtered solution collecting bag hangs on the 22-2-weight sensor, the 22-2-weight sensor is connected with cable with 42-computer and display, collect, calculate and show and filter liquid measure, and the rotating speed of feedback regulation 26-displacement liquid or blood plasma or plasma substitute infusion pump, carry out dynamic infusion on demand; The 4a-dialysate hole of 5-2-paired filtration dialysis device and 4b-dialysate hole are connected with 3b-dialysis solution circulation pipe with 3a-dialysis solution circulation pipe respectively;
The good effect that the present invention and existing background technology comparison are had is: 1, reduced the investment amount of just carrying out blood purification work, helped the difficulty that medical institutions, especially basic medical unit are carried out blood purification work; 2, reduced the blood purification level of technical sophistication, made more medical worker, especially grassroots medical worker grasp manipulating of blood cleaning equipment easily; 3, promoting the use of of present technique equipment helps conserve water resource, favourable to realizing recycling economy, protection environment; 4, promoting the use of of present technique equipment helps quickening the development of China's blood purification cause; 5, the popularization of present technique equipment helps carrying out an other treatment job, the treatment of urgency, Cavity in Critical Patients; 6, owing to used complex technology simplification to design, make the dialysis solution blood circulation of present technique equipment stable and reliable for performance to the dialysis solution blood circulation; 7, since do not rely on the water source, so present technique stronger than traditional haemodialysis control unit adaptability; 8, this device does not rely on water source and water treatment facilities, and the treatment place is required to lower, and can be used as the blood purification equipment of manufacturing products for both peacetime and wartime us; 9, the present technique equipment has the function of hemodialysis, plasmapheresis, three kinds of equipment of CRRT concurrently, can be as a machine three-use, the function that promptly possesses three hsempdiakysing systems in a machine top, so playscript with stage directions machine of purchase, can finish the effect of three hsempdiakysing systems, be that at present domestic and international all equipment that carry out blood purification with extracorporeal circulation of blood do not possess.
Figure 13 is the software work program sketch map of multifunctional easily-transportable artificial kidney of the present invention.
Embodiment: according to Fig. 1～shown in Figure 12, the critical piece of preparation comprises: 1 of (1) blood pump (comprising: micro machine, pump case, pump head and under accessory); (2) 2 of dialysis liquid pumps (comprising: micro machine, pump case, pump head and affiliated accessory); (3) transfusion, 1 of blood transfusion stock pump (comprising: micro machine, pump case, pump head and affiliated accessory); (4) one in computer (special-purpose single-chip microcomputer); (5) one of liquid crystal elecscreen (size and complete machine body shell are complementary); (6) complete machine body shell is one; (7) heparin is injected pump one with platform; (8) electronic clip or flow plug are one; (9) the ultrasonic air gas sensor is one; (10) the electronic scale weighing system is one; (11) electronic heater is one; (12) the metal heat transfer plate is one; (13) universal caster wheel is four; (14) the dialysis solution canister is two; (15) dialysis solution circulation pipe two covers; (16) the dialyser holder is one; (17) dialyser holder and infusion support are one; (18) the transfusion hook weight sensor is one; (19) transfusion platform weight pick off is one; (20) each one connects required electric wire, cable, gong nail, gong medicated cap, anchor clamps, holder, electronic devices and components etc.According to the working procedure software requirement, the design software operational system.Behind the assembling complete machine, debug, finish operation proof and can finish manufacturing after reliable and stable.
Claims (3)
1, multifunctional easily-transportable artificial kidney, it is characterized in that: A. is connected with dialysis solution circulation pipe (3a) by dialysis liquid pump fairlead (2) by the first dialysis solution circulating pump (1), dialysis solution circulation pipe (3a) is connected with the dialysate hole (4a) of dialyser or filter (5-1), the dialysate hole (4a) of dialyser or filter (5-1) is the part of dialyser or filter (5-1), the dialysate hole (4b) of dialyser or filter (5-1) also is that the part of dialyser or filter (5-1) is connected with dialysis solution circulation pipe (3b), dialysis solution circulation pipe (3b) is connected with the second dialysis solution circulating pump (6), by being connected with dialysis fluid container (8) with dialysis solution inlet tube (7), dialysis fluid container (8) places the weighing platform to heat on the Heng Wenban (9), dialysis fluid container temperature measurer probe or liquid temperature table (10) insert in the dialysis fluid container (8), the cable that temperature is preset display (11) and the weighing platform Heng Wenban (9) that heats is connected with computer and display screen (42), predetermined, regulate the heat temperature of Heng Wenban (9) of weighing platform, capacity monitor constitutes the dialysis solution circulation of multifunctional easily-transportable artificial kidney, heat, the weighing apparatus temperature, the capacity monitor system; B. be connected with the form of partly spiraling in pump case with blood pump (13) by ductus arteriosus (12), bubble trap (14) is arranged on the ductus arteriosus (12), exhaustor (15) is arranged on bubble trap (14), ductus arteriosus (12) is connected with the arterial end (16) of dialyser or filter (5-1), the other end of dialyser or filter (5-1) is connected with venous duct (17), bubble trap (18) is arranged on the venous duct (17), coupled exhaustor (19) and venous pressure monitoring pipe (20) are arranged on bubble trap (18), bubble trap on the venous duct (18) continues to prolong afterwards, partly spiral and be connected with flow plug or automatic electric folder (21), venous duct (17) presss from both sides (21) afterwards by flow plug or automatic electric, be connected with patient's internal fistula puncture needle tail pipe or two-chamber large vein puncture tube on one's body, constitute the extracorporeal blood circulation system of multifunctional easily-transportable artificial kidney; C. be connected with displacement liquid hook (23) by weight sensor (22-1), displacement liquid hook (23) and displacement liquid or blood plasma or plasma substitute container (24) are connected, displacement liquid or blood plasma or plasma substitute container (24) are connected with transfusion catheter (25), tube for transfusion (25) and displacement liquid or blood plasma or plasma substitute infusion pump (26) are connected, transfusion catheter (25) partly spirals by behind displacement liquid or blood plasma or the plasma substitute infusion pump (26), be connected with ductus arteriosus (12), constitute the preceding dilution method fluid infusion system of the lasting kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney; D. transfusion catheter (25) partly spirals and is connected by displacement liquid or blood plasma or plasma substitute infusion pump (26) back and the exhaustor (19) on the venous duct bubble trap (18), promptly constitutes the back dilution method fluid infusion system of the lasting kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney; E. be connected in the mode of placing by weight monitoring platform (27) and displacement liquid or blood plasma or plasma substitute tun (28), the transfusion catheter (29) that displacement liquid or blood plasma or plasma substitute tun (28) and displacement liquid or blood plasma or plasma substitute tun are connected is connected, transfusion catheter (29) continuity that displacement liquid or blood plasma or plasma substitute tun are connected forward, partly spiraling is connected with ductus arteriosus (12) by displacement liquid or blood plasma or plasma substitute infusion pump (26), constitutes dilution method fluid infusion system before lasting kidney alternative medicine (CRRT) another kind of of multifunctional easily-transportable artificial kidney; E. transfusion catheter (29) continuity that is connected by displacement liquid or blood plasma or plasma substitute tun forward, the exhaustor (19) that links to each other with bubble trap (18) on the venous duct (17) by displacement liquid or blood plasma or plasma substitute infusion pump (26) back that partly spirals is connected, and constitutes the back dilution method fluid infusion system of another kind of the lasting kidney alternative medicine (CRRT) of multifunctional easily-transportable artificial kidney; G. linked by connecting tube (30) one ends and dialyser or filter (5-1), the arterial end of the other end and perfusion device (31) links, and the vein end of perfusion device (31) and venous duct (17) link, and promptly constitute the structure of hemodialysis perfusion system; H. be connected with blood drainage pipe (33) by disposable Membrane Plasma Separator (32), blood plasma drainage tube (33) inserts in the blood plasma drainage container (34), there is exhaustor (35) to insert in the blood plasma drainage container (34) simultaneously, blood plasma drainage container (34) places the weighing platform to heat on the Heng Wenban (9), displacement liquid or blood plasma or plasma substitute container (24) hang on the displacement liquid hook (23), one end of transfusion catheter (25) and displacement liquid or blood plasma or plasma substitute container (24) are connected, the other end partly spirals and is connected with exhaustor (19) on the venous duct bubble trap (18) by displacement liquid or blood plasma or plasma substitute infusion pump (26) back, constitutes disposable blood plasma separation replacement therapy hardware system; I. partly spiral by ductus arteriosus (12) and be connected with blood pump (13), by being connected with disposable Membrane Plasma Separator (32) again behind the blood pump (13), the blood plasma tap of disposable Membrane Plasma Separator (32) lower end is connected with blood plasma drainage tube (33), blood plasma drainage tube (33) continues and is connected with blood plasma thermostat (36) forward, behind blood plasma thermostat (36), partly spiral and be connected with separator of blood plasma components (37) by displacement liquid or blood plasma or plasma substitute infusion pump (26), the healthy blood plasma of separating through separator of blood plasma components (37) feeds back pipe (39) by blood plasma and is connected with exhaustor (19) and can feeds back healthy blood plasma, the cause of disease blood plasma of separating from separator of blood plasma components (37) that has has cause of disease blood plasma to dump pipe (38) to be connected with discarded blood plasma container (34) and can to have dumped cause of disease blood plasma by what be connected with separator of blood plasma components (37), constitutes dual blood plasma components and separates and feed back hardware system; J. linked with anticoagulant infusion tube (41) by anticoagulant syringe pump and anticoagulant syringe (40), anticoagulant infusion tube (41) links with ductus arteriosus (12), constitutes anticoagulant and keeps adding system; K. partly spiral by the pump line section of ductus arteriosus (12) and be connected with blood pump (13), be connected with disposable blood plasma separator (32) more afterwards, the vein end of Membrane Plasma Separator (32) is connected with venous duct (17), bubble trap (18) is arranged on the venous duct (17), venous duct is connected with patient's puncture needle tail pipe or conduit on one's body after continuity is by flow plug or automatic electric folder (21); Displacement liquid or blood plasma or plasma substitute container (24) are connected with transfusion catheter (25), the second dialysis solution circulating pump (6) as displacement liquid or blood plasma or plasma substitute infusion pump, transfusion catheter (25) partly spirals by being connected as the approach of transfusion or plasma transfusion or blood plasma substitute as the second dialysis solution circulating pump (6) of displacement liquid or blood plasma or plasma substitute infusion pump exhaustor (19) back and on the bubble trap, the blood plasma tap of Membrane Plasma Separator (32) is connected with blood plasma drainage tube (33), blood plasma drainage tube (33) is connected with plasma collection container (34), exhaustor (35) is arranged on the plasma collection container (34), constitute the metathetical hardware system of another disposable blood plasma; L. partly spiral by the pump line section of ductus arteriosus (12) and link with blood pump (13), partly spiral and detour afterwards by blood pump (13), be connected with the arterial end of disposable Membrane Plasma Separator (32), the vein end of disposable Membrane Plasma Separator (32) is connected with venous duct (17), bubble trap (18) is arranged on the venous duct (17), venous duct (17) joins with patient's puncture needle tail pipe or double lumen tube on one's body after continuity is by flow plug or automatic electric folder (21); The blood plasma of separating from disposable Membrane Plasma Separator (32), be connected with the blood plasma upstream end of separator of blood plasma components (37) by blood plasma drainage tube (33) the first dialysis solution circulating pump (1) that detours by as the plasma circulation pump that partly spirals, cause of disease blood plasma is arranged and have cause of disease blood plasma to dump pipe (38) to be connected, to have cause of disease blood plasma to dump pipe (38) and be connected from what separator of blood plasma components branch (37) was separated with discarded plasma collection container (34); The no cause of disease blood plasma of separating from separator of blood plasma components (37), feeding back the exhaustor (19) that pipe (39) links to each other with bubble trap (18) on the venous duct (17) by the blood plasma that is connected with separator of blood plasma components (37) is connected, displacement liquid or blood plasma or plasma substitute container (24) are connected with transfusion catheter (25), the second dialysis solution circulating pump (6) as displacement liquid or blood plasma or plasma substitute infusion pump, transfusion catheter (25) partly spirals by being connected as the approach of transfusion or plasma transfusion or blood plasma substitute with exhaustor (19) on the bubble trap as the second dialysis solution circulating pump (6) of displacement liquid or blood plasma or plasma substitute infusion pump back, constitutes the metathetical hardware system of another dual separating plasma; M. partly spiral by the pump line section of ductus arteriosus (12) and be connected with blood pump (13), partly spiral and detour afterwards by blood pump (13), be connected with ductus arteriosus bubble trap (14), exhaustor (15) is arranged on the bubble trap (14), ductus arteriosus (12) continues continuity forward, be connected with the arterial end (16) of paired filtration dialysis device (5-2), the vein end of paired filtration dialysis device (5-2) is connected with venous duct (17), exhaustor (19) and vein pressure pipe (20) are arranged on the bubble trap (18) on the venous duct (17), venous duct (17) continues forward, detour and press from both sides (21) afterwards by flow plug or automatic electric, be connected with patient's internal fistula puncture needle tail pipe or two-chamber large vein puncture tube on one's body, constitute the extracorporeal blood circulation system of multifunctional easily-transportable artificial kidney pairing dialysis filtration system, the filtered solution of discharging by the filtered solution tap (4c) of paired filtration dialysis device (5-2), by filtered solution collecting pipe (4d) drain to filtered solution collecting bag (4e), filtered solution collecting bag (4e) hangs on the weight sensor (22-2), weight sensor (22-2) is connected with cable with computer and display (42), collect, calculate and show and filter liquid measure, and the rotating speed of feedback regulation displacement liquid or blood plasma or plasma substitute infusion pump (26), carry out dynamic infusion on demand;
2, according to the described multifunctional easily-transportable artificial kidney of claim 1, its feature also is: the dialysis solution circulation of A. multifunctional easily-transportable artificial kidney, heat, the weighing apparatus temperature, the working procedure of capacity monitor system is: A-1 places dialysis fluid container (8) the weighing platform to heat on the Heng Wenban (9), dialysis solution fairlead (2) and dialysis solution inlet tube (7) are inserted respectively in the dialysis fluid container (8), start the first dialysis solution circulating pump (1) and the second dialysis solution circulating pump (6), dialysis solution is sent to the dialysate hole (4a) of dialyser or filter (5) through dialysis solution circulation pipe (3a), dialysis solution arrives its other end dialysate hole (4b) through dialyser or filter (5-1), through dialysis solution circulation pipe (3b), by the second dialysis solution circulating pump (6), dialysis solution is introduced in the dialysis fluid container (8) through dialysis solution inlet tube (7); A-2 ultrafiltration program is: according to the ultrafiltration volume that presets, automatically adjust the second dialysis liquid pump (6) by computer and display (42) and realize ultrafiltration with the speed discrepancy of the first dialysis liquid pump (1), adopt a gram to be the weight sensor of unit, ultrafiltration volume in dynamic unit of adjustment's time, by the weighing platform Heng Wenban (9) that heats alleged weight is continuously fed back to computer and display (42), dynamically revise ultrafiltration volume, until the amount of setting that reaches in the unit interval, go up pressurization or decompression action if accident occurs at dialysis fluid container (8) in treatment, setting is ignored program and is got rid of interference; The heat program of weighing apparatus temperature of A-3 is: according to indoor environment temperature, set in advance the temperature of the Heng Wenban that heats (9), and be presented on default display (11) of temperature and the machine calculation machine screen (42), by the Heng Wenban that heats (9) the temperature indirect transfer to dialysis fluid container (8), reach control, the temperature of (8) the middle dialysis solution of keeping dialysis fluid container; B. the working procedure of the fluid infusion of multifunctional easily-transportable artificial kidney, transfusion, plasma transfusion or blood plasma substitute is: B-1 hangs on displacement liquid or blood plasma or blood plasma substitute (24) on the displacement liquid hook (23), one end of transfusion catheter (25) and displacement liquid or blood plasma or blood plasma substitute (24) are connected mutually, the other end is connected with transfusion short tube on the ductus arteriosus (12), or be connected for the exhaustor (19) on the bubble trap of one (18) with venous duct (17), dilution or back dilution method fluid infusion perhaps replenish blood plasma, blood plasma substitute etc. before carrying out; B-2 is positioned over displacement liquid or blood plasma or plasma substitute tun (28) on the weight monitoring platform (27), displacement liquid or blood plasma or plasma substitute tun (28) are connected with transfusion catheter (29), transfusion catheter (29) continuity forward, partly spiraling is connected with ductus arteriosus (12) by displacement liquid or blood plasma or plasma substitute infusion pump (26), constitutes dilution method fluid infusion system before lasting kidney alternative medicine (CRRT) another kind of of multifunctional easily-transportable artificial kidney; B-3 is positioned over displacement liquid or blood plasma or plasma substitute tun (28) on the weight monitoring platform (27), the connection tube of displacement liquid or blood plasma or plasma substitute tun (28) is connected mutually with transfusion catheter (29), transfusion catheter (29) continuity forward, partly spiral by displacement liquid or blood plasma or plasma substitute infusion pump (26) back and venous duct (17) to the exhaustor (19) on the bubble trap of one (18) is connected, carry out back dilution method fluid infusion, plasma transfusion etc.; C. the working procedure of multifunctional easily-transportable artificial kidney paired filtration dialysis system is: the filtered solution collecting pipe (4d) of paired filtration dialysis device (5-2) and filtered solution hole (4c) are linked, filtered solution collecting bag (4e) is hung on the hook of weight sensor (22-2), the filtered solution weight that computer and display (42) are fed back according to weight sensor (22-2) increases the displacement liquid weight that data and weight sensor (22-1) fed back and reduces data, dynamically adjust the rotating speed of displacement liquid or blood plasma or plasma substitute infusion pump (26), carry out dynamic infusion on demand;
3, according to the described multifunctional easily-transportable artificial kidney of claim 1, its feature also is: the software work program of multifunctional easily-transportable artificial kidney is: after computer and control panel (42) startup is started working, promptly being in stress duty, heat after platform (9) goes up when dialysis fluid container (8) being positioned over weigh, computer promptly weighs up the weight of dialysis fluid container (8), behind the beginning dialysis treatment, the first dialysis solution circulating pump (1) starts, by dialysis liquid pump fairlead (2) dialysis solution is drawn, through dialyser or filter (5-1), taken out to draw by the second dialysis solution circulating pump (6) and send dialysis fluid container (8) back to, when needs increase ultrafiltration, the second dialysis solution circulating pump (6) is according to computing information value speedup, and when needs reduced ultrafiltration, the second dialysis solution circulating pump (6) slowed down according to the computing information value; When accident weighing heat increase on the platform (9), during the loss of weight amount, the program of ignoring of design is promptly given and being ignored; Dialysis solution from the first dialysis solution circulating pump (1) is drawn joins to conductivity sensor and with lead and computer according to catheter drainage, with the conductivity of prompting dialysis solution; Actual temperature according to dialysis solution is as the criterion, and sets the temperature of dialysis solution, and when dialysate temperature is lower than the physiological need temperature, the platform (9) of heating of weighing is promptly opened and heated; When dialysate temperature reaches required physiological temp, the platform (9) of heating of weighing promptly stops to heat; Behind the dialysis treatment result, the time of setting sterilization dialysis solution circulation pipe is 0～60 minute, arrives when the disinfectant time, and the first dialysis solution circulating pump (1) and the second dialysis solution circulating pump (6) promptly stop automatically; When carrying out the cleaning of dialysis solution circulation pipe sterilization back, adorn 5000～10000ml reverse osmosis water or aquae destillata with dialysis fluid container (8), dialysis liquid pump fairlead (2) is inserted in reverse osmosis water or the aquae destillata, dialysis solution inlet tube (7) is inserted in another dialysis fluid container, start dialysis liquid pump (1) and (6), make reverse osmosis water or aquae destillata flow into another dialysis fluid container from dialysis fluid container (8), when the cleanout fluid in the dialysis fluid container (8) (reverse osmosis water or aquae destillata) weight during greater than 200g (200ml), cleaning is proceeded, when cleanout fluid weight during less than 200g (200ml), computer (42) starts multifunctional easily-transportable artificial kidney and shuts down automatically; Weight sensor (22-1; 22-2) displacement liquid or blood plasma or plasma substitute container (24) and filtered solution collecting bag (4e) in continuous monitoring respectively, calculating monitoring by computer and display (42), the data and filtered solution collecting bag (4e) weight that lighten according to displacement liquid or blood plasma or plasma substitute container (24) weight become heavy data variation, regulate the rotating speed of displacement liquid or blood plasma or plasma substitute infusion pump (26) continuously, dynamically control the speed of transfusion or blood plasma or plasma substitute.
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| CNA2006100708097A CN1879901A (en) | 2005-03-24 | 2006-03-11 | Multifunctional easily-transportable artificial kidney |
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| CN100493633C (en) * | 2007-04-27 | 2009-06-03 | 高光勇 | Artificial system for supporting liver and kidney |
| CN102105581B (en) * | 2008-07-02 | 2013-09-04 | 株式会社大塚制药工场 | Artificial kidney precursor and process for production thereof |
| CN103381276A (en) * | 2013-07-31 | 2013-11-06 | 河南科技大学第一附属医院 | Hemoperfusion and dialysis device |
| CN103845768A (en) * | 2007-02-27 | 2014-06-11 | 德卡产品有限公司 | Hemodialysis systems and methods |
| CN105169507A (en) * | 2009-08-04 | 2015-12-23 | 弗雷塞尼斯医疗保健控股公司 | Dialysis systems, components, and methods |
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| CN103845768A (en) * | 2007-02-27 | 2014-06-11 | 德卡产品有限公司 | Hemodialysis systems and methods |
| CN103845768B (en) * | 2007-02-27 | 2016-09-28 | 德卡产品有限公司 | Hemodialysis system and method |
| US10441697B2 (en) | 2007-02-27 | 2019-10-15 | Deka Products Limited Partnership | Modular assembly for a portable hemodialysis system |
| CN100493633C (en) * | 2007-04-27 | 2009-06-03 | 高光勇 | Artificial system for supporting liver and kidney |
| CN102105581B (en) * | 2008-07-02 | 2013-09-04 | 株式会社大塚制药工场 | Artificial kidney precursor and process for production thereof |
| CN105169507B (en) * | 2009-08-04 | 2018-04-06 | 弗雷塞尼斯医疗保健控股公司 | Dialysis system, part and method |
| CN105169507A (en) * | 2009-08-04 | 2015-12-23 | 弗雷塞尼斯医疗保健控股公司 | Dialysis systems, components, and methods |
| CN103381276A (en) * | 2013-07-31 | 2013-11-06 | 河南科技大学第一附属医院 | Hemoperfusion and dialysis device |
| CN105879137A (en) * | 2014-09-15 | 2016-08-24 | 彭罗民 | A life activation instrument |
| CN105496696A (en) * | 2015-12-21 | 2016-04-20 | 崔红霞 | Hemodialysis auxiliary nursing device |
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