CN1663554A - Method and application for building movable Chinese medicine processing plant - Google Patents
Method and application for building movable Chinese medicine processing plant Download PDFInfo
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- CN1663554A CN1663554A CN 200510038030 CN200510038030A CN1663554A CN 1663554 A CN1663554 A CN 1663554A CN 200510038030 CN200510038030 CN 200510038030 CN 200510038030 A CN200510038030 A CN 200510038030A CN 1663554 A CN1663554 A CN 1663554A
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Abstract
The invention discloses a method for building movable processing shop for traditional Chinese drug and its application on processing field for traditional Chinese drug (natural drug), which changes traditional processing and operating pattern for Chinese drug, exactly is not only comprises apparatus and mechanical equipment for detecting, analyzing, processing ( roasting in a pan), producing (extracting and purifying) and packaging, but also have enclosed and movable space or room accorded to identification and requirement of drug ''GMP'', moves to producing area where drug is planted or bred, buys fresh crude drugs develop, producing for Chinese drug, and analyzes and draws up drug fingerprint pattern during producing process on site, controls quality and drug effect of the medicinal plant compared with corresponding standard fingerprint pattern, looks for cause when error appears in time on source, and avoids blind production.
Description
Affiliated technical field
The present invention relates to a kind of mobile Chinese medicine job shop, specifically be exactly by the place, movably space of detecting, analyzing, instrument such as processing (processs of preparing Chinese medicine), production (extraction and purification), packing and pharmaceutical machine equipment have the sealing that meets medicine " GMP " authentication requesting when being formed.Move to the medical material plantation, support and plant the place of production, the fresh medical material of on-the-spot purchase is carried out Chinese medicine production.
Belong to pharmaceutical machine equipment and Chinese medicine production field, equally also adapt to the natural drug production field.
Background technology
Chinese medicine is the rarity of the Chinese nation, in very long historical long river, for indelible contribution has been made in the substantial and development of world medicine.Along with the raising of science and technology development and people's living standard, to possess new theories such as technology, detection, analysis, technology, management to the Chinese medicine production field, can satisfy people to the more and more stricter requirement of Chinese medicine quality.
As everyone knows, the quality of China's Chinese crude drug is extremely unstable, and market is also comparatively chaotic.Therefore, quality instability, uncontrollable raw material are carried out the production of Chinese medicine processing and preparation, even production link carries out in strict accordance with the GMP standard, its quality can not reach controlled requirement equally.As seen, Chinese medicine quality wants to reach controlled and stability requirement, should make the plantation of Chinese crude drug culture standardization earlier, begin detection, each processing link of analysis means whole process supervision of application of advanced in the source, improve technological standardss such as the Chinese crude drug process of preparing Chinese medicine, Chinese crude drug extract, Chinese patent medicine and drug packaging, guarantee that pharmaceutically active ingredient has detailed data or finger printing record in pharmacy procedure, and normal data or finger printing control test are arranged, find quality problems processing in time and adjust.
Stable, controlled in order to ensure Chinese medicine quality, Chinese medicine takes the lead in implementing the finger printing Quality Control technology of formulation Chinese crude drug, extract, Chinese medicine finished product under the prerequisite of fixedly traditional Chinese medicinal materials assortment, the place of production and collection period.It is to realize the modern important symbol of Chinese medicine that fingerprint pattern technology is used, and finger printing is the important pass that Chinese medicine enters the international market.This material amount and set up the Chinese crude drug finger printing of all requiring to begin to prepare medicines from a Chinese precription from the source.
The Chinese crude drug finger printing means that Chinese crude drug after suitably handling, adopts certain analysis means, the collection of illustrative plates at the total peak that can indicate this Chinese crude drug characteristic that obtains.Formulate crude drug (crude drug) and processed product (claim the prepared slices of Chinese crude drugs again or claim ripe medicine) finger printing, be to provide the quality control foundation for following one pharmacy link, can be by detecting and analyzing a certain kind Chinese crude drug, need be as crude drug through special processing (as vinegar system, processed with wine, parch to black etc.) finger printing, the finger printing inspection that contrasts this breed standard has zero deflection and unusual, thereby control the quality and the drug effect of this Chinese crude drug, discovery has error in time to look for reason adjusted in the source, avoid blindly producing in enormous quantities, cause unnecessary loss and waste, the stable and effective control of only guaranteed Chinese crude drug raw materials quality just might guarantee the quality of Chinese medicine product.
At present, the fixedly medical material place of production is mostly selected by all kinds of herbal pharmaceutical enterprise, and the GAP in the medical material construction of base formulates and implements, and has embodied enterprise raw material production is paid much attention to.Great mass of data shows that its constituent content of same medical material in the different places of production is widely different.Many indicator of product variety component contents differ and can reach more than 10 times.As the contained chlorogenic acid of Flos Lonicerae high have 3.42%, low ability 0.45%; What the contained Herba Epimedii glycoside of Herba Epimedii was high has 3.00%, low ability 0.14%; What the contained astragaloside of the Radix Astragali was high has 0.30%, low ability 0.013%, and so on.So, must measure on the basis relatively with modern science at the genuine Journal of Sex Research of tradition, choose the place of setting up the medical material base from the whole country.
Herbal mixture includes the kinds of traditional Chinese medicines material, and manufacturing enterprise need set up a plurality of medical materials place of production, and each medical material base is distributed throughout the country again, enterprise will guarantee every kind of crude drug quality, just must set up " first job shop ", medical material is carried out " process of preparing Chinese medicine ", promptly produce the prepared slices of Chinese crude drugs in the base.Just there is following point in this:
(1), also there are far away or near transportation range in fixed " first job shop " and the medical material planting site set up in each medical material base, and the secondary pollution phenomenon is arranged in transit.
(2), Chinese medicine processing is traditional pharmaceutical technology of a uniqueness of the preparation prepared slices of Chinese crude drugs, is first procedure of processing medical material, fixed " first job shop ", with regard to same kind, because processing condition, method and grasp degree varies, big gun causes, often cause the physicochemical property and the curative effect difference of medicine.In concocting the course of processing, also be subjected to weather at that time, the collecting period, concoct factor affecting such as plant equipment, decoction pieces (general name of each crude drug processed product) quality has fluctuation, and its quality has direct influence to the curative effect and the pharmacy back segment link of prescription.In order to ensure the quality after the medicinal material processing technology or check its quality condition, various places " first job shop ", increase detect with analytical tool monitoring raw medicinal material to the decoction pieces production process, this fund of just stepping up its investment has improved cost.
(3), the GAP of every kind of medical material correspondence cultivates the cultivation base, repeat to set up fixed " first job shop ".If small scale, equipment and technology content is low, does not have analytical tool, can't carry out finger print identification, can influence the quality that decoction pieces is produced, and quality also can't be effectively controlled; If the check and analysis instrument and pharmaceutical processing (process of preparing Chinese medicine) mechanized equipment of high standard are installed, need supporting high standard workshop building and input, find after coming into operation, the annual collecting period one crosses can cause equipment and Factory Building to leave unused, utilization rate of equipment and installations is low, enterprise also will have the rear personnel to nurse Factory Building and maintaining equipment every year in various places, strengthened the production run cost.
Summary of the invention
Goal of the invention: decoction pieces is on-the-spot the process of preparing Chinese medicine and packing and attached its finger printing and original producton location information in the original producton location.
The invention thinking: traditional mode of production, promptly the Chinese medicine job shop comprises the analyzing and testing laboratory and fixes, and raw medicinal material is plucked entrucking from planting site and is transported fixed Chinese medicine job shop to, and its transportation Chinese crude drug quality changes uncontrollable; Change into: the Chinese medicine job shop comprises the analyzing and testing laboratory and moves to the raw medicinal material planting site, the on-the-spot processing and packing of concocting is good and analyze and make finger printing and making place of production news file, medicinal raw material does not have that transit link is also corresponding to have reduced the link that quality easily goes wrong in the planting site, begin to analyze the contrast of medicinal materials fingerprint and standard finger-print from the source, pinpoint the problems and in time adjust, quality is subjected to effective control.
The Chinese medicine job shop that moves at first will make the space that constitutes the Chinese medicine job shop move, and various check and analysis instruments and the Chinese medicine process equipment installed within it also move with it with regard to corresponding, move to meet the law on road traffic safety; Also to make the space that constitutes the Chinese medicine job shop can make up and amplify, satisfy medicinal raw material and instrument and equipment and workman and operate required space requirement, and can carry out udst separation to the space and handle, make it meet drug quality working system (medicine GMP authentication).
Along with the maturation utilization of container and insulation material science and technology development and clean technology, particularly the raising of automobile industry overall technology and price descend significantly, for the invention provides lower material base of expense and high performance technical guarantee.
In order to solve fixed workshop in existing Chinese medicine processing and the production field, produce a series of problems that decoction pieces exists in the medical material base, also will improve working (machining) efficiency and product specification simultaneously, guarantee that quality of medicinal material is stable, controlled, the technical solution adopted in the present invention is:
The traditional medicine processing machinery tool of various advanced persons' specialty and package packing machine and health are detected and analytical tool, be installed in respectively by functional requirement classification in the car body of sealing of different temperature controls, formed one to the different Chinese medicine processing special-purpose vehicle of multi-section function, to the medical material original producton location, these car body are spliced and combined into the Chinese medicine job shop of the sealing of a mobile temperature control with the order of Chinese medicine processing process; And utilize clean technology that combination type air promptly is installed on car body and handle unit and dust removal process unit, to the car body that needs the sterile working or in it space of corresponding toilet heat, cooling, sterilization, sterilization, filtration treatment, make it meet medicine GMP authentication, can carry out Chinese medicine processing, its product comprises semi-finished product and all has medical material original producton location information and finger printing.
Form by two parts in above-mentioned this technical scheme:
First: how to set up the Chinese medicine job shop of sealing of the temperature control of a mobile combination, make it satisfy corresponding Chinese medicine production scale (site space) requirement;
Second portion: how to solve the hygienic requirements of Chinese medicine job shop, make it satisfy the pharmaceutical production hygienic requirements;
At first, first sets up the Chinese medicine job shop of sealing of the temperature control of a mobile combination, needs to solve the mobility of Chinese medicine job shop; Instrument, equipment are installed with the workman and are operated required space and composite behaviour; Temperature control and these three technical problems of sealing, it is as follows respectively to solve its technical characterictic of technical scheme that these three technical problems take:
(1) mobility of Chinese medicine job shop
The haulage vehicle that meets " law on road traffic safety " and " road vehicle contour dimension, axle load and quality limit value " regulation on the market has: automobile, trailer, truck combination.
Automobile branch: lorry and tractor truck; Passenger car and passenger vehicle.
Trailer branch: semitrailer; Mid-axle (sojourning in) trailer; Other trailers.
Truck combination branch: articulated train, freight trains.
The present invention is preferred, is carrying the means of transport that container combines on the tractor truck in the automotive-type and trailer apoplexy due to endogenous wind semitrailer and the semitrailer.Promptly this car by tractor-truck and container (this paper the claims car body) two parts of partly pulling carrying form, tractor-truck and car body are separable.Be convenient to head and the tail " one " font butt joint between the car body.Partly pull the car body that the container of carrying is formed, its container of partly pulling and carrying is partable also, partly pulls to unload the container that lands and can use separately, looks practical situation and applies in a flexible way.
The present invention is preferred, only change the internal container structure, do not change automobile and trailer any part, the total external dimensions of container of automobile and trailer carrying will meet above-mentioned " two methods " regulation, be that beam overall is no more than 2500MM, height overall is no more than 4000MM, and length is no more than the length of selected vehicle " two methods " regulation.
" car body " that claims in the present disclosure be meant semi-trailer carrying container constituted.
" in the car body " in fact is meant in the container body.
" special-purpose vehicle " is meant by the internal container of tractor truck head and semi-trailer carrying the special-purpose vehicle of the processing Chinese medicine function that equipment had has been installed.Tractor truck head and semi-trailer do not have a tiny bit and change.Do not belong to and transform the category that the formed special-purpose vehicle of vehicle structure need be examined.Special-purpose vehicle of the present invention meets above-mentioned " two methods ", can set out on a journey and travel, and has solved the ambulant problem of Chinese medicine job shop.
(2) the instrument processing mechanical packaging equipment in the Chinese medicine job shop is installed and required space and the composite behaviour of workman's process operation
The preferred container of the present invention, the container technology maturation, technology advanced person, selected material is corrosion-resistant, and it is firm in structure, meets traffic condition again.
Container Dimensions has:
10′×8′×8′6″；10′×8′×9′6″：
20′×8′×8′6″；20′×8′×9′6″；
40 ' * 8 ' * 8 ' 6 "; 40 ' * 8 ' * 9 ' 6 "; Six kinds of international standard sizes.
Container can be according to the needs of Chinese medicine job shop, select a kind of in above-mentioned six kinds of international standard sizes different in size, also can customize the container or the irregular casing that has living space of the off-standard size that meets " two methods " regulation as required.
Internal container itself just has very big space, single internal container:
Cleaning, the choosing that raw material is installed chosen, conveying, elevating mechanism are exactly that a pretreatment of raw material adds break;
It is exactly that a process of preparing Chinese medicine adds break that medicinal material processing machinery is installed;
Install to extract, separate, concentrate, purification, drying, sterilization machinery be exactly between a deep processing;
Sewage disposal device is installed has just been become the sewage disposal workshop;
The passage that shower cabinet antiseptic hand washing pond has just become workman's dressing cubicle and entered job shop has been installed;
Health check and analysis instrument is installed has just been become to defend inspection analysis quality control room;
Miniature boiler equipment is installed has just been become the boiler water treatment room with water treatment system;
Be equipped with the toilet what be used for drug packaging is exactly (needing medicine GMP authentication) between drug packaging;
Installation sleeve mark, coding, vanning machinery and purify new blower fan group to carry out that sterile air handles be exactly between outer package;
Equally, internal container space can cut off and be divided into several little spaces and adorn the Chinese medicine process equipment respectively, that is to say and can be installed in several equipment continuously in the container of a big length by the functional requirement order.
All by the semi-trailer carrying, the car that correspondingly carries them has just become the special-purpose vehicle of the processing Chinese medicine function that is determined by erection unit to above-mentioned container.
Two containers just between two car body form of putting have:
Side by side near putting:
In Fig. 1,
M and D and N;
Dislocation is near putting:
In Fig. 1,
A and E;
F and A and B;
" one " font is near putting from beginning to end:
In Fig. 1,
A and B and C and D;
" fourth " font is near putting:
In Fig. 1,
G and B;
C and L;
H and L;
N and P;
N and O.
Near putting just and can connect: concrete connected mode, at first each self-corresponding risers that will connect at two containers is opened onesize door, and door can be a sliding door, also can vertical hinged door, closing door when not connecting separately.Vertical hinged door is wanted earlier door to be opened as towards external-open, and put near pendulum (stopping) back.During connection, open separately behind the door, the door pocket of being made by insulation material is installed around door opening separately, sealing is closely fixing around door pocket and the door opening, the width of door pocket (or degree of depth of title door pocket) is put 1/2nd of distance less than two car body, the connection doorframe of being made by insulation material of putting distance of being wider than is embedded in the two car body door pockets, the effect of door pocket is and connects between the doorframe bigger contact surface and space are arranged, the purpose that leaves the space between door pocket and the connection doorframe is to eliminate the error that pendulum (stopping) brings when putting between two car body, with insulation rubber bar space good seal around the connection doorframe that embeds in the two car body door pockets and between the door pocket, by connecting doorframe two car body inner spaces are coupled together, and seal with the external world.Vertical hinged door or the sliding door of being made by insulation material installed at two that can promptly connect doorframe in two car body the insides of correspondence as required that connecting doorframe has separately, the car body passage dual face seals that connects two connections of two door knobs on the doorframe, play buffer compartment from the effect of grade, adapt to the MGP authentication requesting.
Door and the corresponding with it doorframe width that plays interconnect function require corresponding changeable with height according to the Chinese medicine work flow:
Be people's walkway, but point; Be the material transmission channel, can wide point.If it is very big that two containers putting side by side connect door at the length side facade, two containers have satisfied the space width requirement together with connecting the corresponding width that increases interblock space of doorframe, specifically can be according to the size of technological process and needs arrangement design gate.
Be pipe passage, need not to open the door, want the junction at two containers, carry out pipe joint in advance, during connection, the heat-preserving hose with big several covers connects good seal outside earlier, again the pipeline that will connect is through the middle equipment that connects in two containers of heat-preserving hose.Both simple, convenient again.
Two containers just between two car body type of attachment have: side by side; Dislocation; " one " font from beginning to end; " fourth " font.
Type of attachment side by side:
In Fig. 1,
M and D and N;
The dislocation type of attachment:
In Fig. 1,
A and E;
F and A and B;
" one " font type of attachment from beginning to end:
In Fig. 1,
A and B and C and D;
" fourth " font type of attachment:
In Fig. 1,
G and B;
C and L;
H and L;
N and P;
N and O.
In twos can be between the car body according to the requirement of Chinese medicine processing technique, with above-mentioned four kinds of types of attachment, but assembly unit goes out the space that required installation processing equipment, package packing machine, health check and analysis instrument and the workman of Chinese medicine processing operates required Any shape.The length of interblock space and width also have following typical method:
Spatial extended length method:
The single container length of length 12000MM, height 3000MM, width 2500MM is not enough, onesize two or three and even four container head and the tail " one " fonts can be connected, total length is 24000MM, 36000MM or 48000MM, and the medicine transmission line forms a long middle leechdom production line in enough installing;
Spatial width extended method:
With length 6000MM, height 3000MM, the data instance of width 2500MM, if single container width is not enough, can put two parallel pendulum of container (stopping), pendulum (stopping) is put the height that distance equals container, the corresponding container side elevation that will connect is transformed, 1/2 place of container side elevation disconnects, side elevation all hinges up and down, formed as seeing in our daily life that vertical hinged door revolves and turn 90 degrees, promptly one is turned over up, one is turned over down, with two blocks of rectangle sheet materials that contain insulation material of a size, length equals container length, width 500MM-1000MM, middle be used for pressing from both sides the junction of turning on two in the container by holding screw, the connected mode of junction is as revolving " H " font that turn 90 degrees, and promptly the two boards material is two " | " of H, and holding screw is H "-", the centre of H press from both sides respectively two containers on turn over the junction, it is to be used for the surplus of putting to the error that container pendulum (stopping) brings when putting that the middle joint of H junction leaves the space.Behind the fit sealing of H junction and horizontal steel pipe on housing between two containers fix, adjustable height, guarantee two containers on to turn over the junction parallel.In like manner, the connection H connection like this of turning under two containers.That face at container 2500MM width is equipped with sliding door, and the sliding door of two faces of two containers has just turned over formed space closure to two containers up and down to pushing away, and space width has formed 8000MM.
If side elevation of container disconnects at 1/3 place, another container side elevation should disconnect at 2/3 place, all hinges up and down, connects like this to guarantee the upper and lower height that addition respectively all equals container that turns over.Adjustable ratio is whole, it is called the space width expansion turns over the whole H connection method of adjustable ratio up and down.
Also having way is exactly that to press upper hinge at container side elevation gap movable, above one in two containers hinge is installed, below another container hinge is installed, promptly an integral body is turned over up, an integral body is turned over down, turn in the process, it is movable folding to press upper hinge by gap, directly be installed to corresponding top of container and bottom, that face at container 2500MM width is equipped with sliding door, and the sliding door of two faces of two containers is to pushing away, just the whole side of two containers has been turned over formed space closure up and down, space width has formed 8000MM.It is called space width expansion lateral hinges connection method.
Three containers are drawn analogous conclusions, and it is 13500MM that the space can form width.
Car body by one or more special-purpose vehicles has combined the needed space of Chinese medicine job shop like this.The size of Chinese medicine job shop can be changeable according to Chinese medicine processing variety needs, also keeping the mobility of Chinese medicine job shop.
Composite behaviour has two implications, and its technical characterictic is: the space that is combined by the car body of one or more or tens special-purpose vehicles can be satisfied the requirement of Chinese medicine job shop scale, i.e. spatial organization fully; The machining functions of Chinese medicine job shop also can be changed by the variation of changing a certain special-purpose vehicle, i.e. function combinations.As: the processing process of preparing difference among Fig. 1, the process of preparing Chinese medicine equipment replacement of B or the replacing of C car or its inside, and other as extract, separate, concentrate, special-purpose vehicles such as purification, drying, sterilization, packing need not change, just can process by the prepared slices of Chinese crude drugs of changing the decoction pieces kind that special-purpose vehicle process of preparing Chinese medicine determined; Increase by process of preparing Chinese medicine equipment combination in different special-purpose vehicle combinations or the car body, its machining functions increases, and utilization rate of equipment and installations is high.
(3) temperature control of Chinese medicine job shop and sealing
Around the container in the above-mentioned car body of mentioning, inwall is to form with the insulation material transformation, or customizes container with insulation material, has solved the insulation problem.
Car body inside can be according to the processing technique needs, what have cuts off into the plurality of sections space, in outside, corresponding top refrigeration unit is installed, and at the corresponding inner temperature inductor of installing, the refrigeration unit of control outside provides needed temperature and humidity to this partition space segment.The maturation utilization of vehicle-mounted refrigeration unit has solved temperature control and humidity and has concocted required spatial environments problem.
Container itself just has sealing, connection between them is a kind of to embed in the two car body door pockets by connecting doorframe, good seal around the doorframe that embeds in the two car body door pockets, door pocket contact surface around doorframe is bigger, can guarantee that its sealing is good with insulation rubber bar; It is that pipe passage connects that another kind between them connects, need not to open the door, two equipment that connect separately the container at place to connect the peripheral interface place, heat-preserving hose with big several covers connects good seal outside earlier, the pipeline that will connect is through on the middle equipment that connects in two containers of heat-preserving hose again.Pipeline connects two equipment, good seal performance in the middle of being through heat-preserving hose.
Certainly, this programme also can be formed by the manufacturing of above-mentioned three major types vehicle car, but must vehicle supervision department examines by; Also available heat preservation plate material transports the planting base to by automobile and is assembled into active Factory Building, operationalizes cumbersome like that.
The container that this programme adopts also can change the irregular casing that has living space that meets traffic condition into.
A complete Chinese medicine processing process, need to form by some processing links, equipment that each link is required and ambient temperature and environment cleanliness require also different, a required armamentarium of complete Chinese medicine processing process is installed in the multi-section car body according to the different segmentations of function, each section temperature and cleanliness factor in each car body, according to the needs may command of technology, formed the Chinese medicine job shop that moves that forms by the aseptic special-purpose vehicle of the sealing of the different temperature control of multi-section function.
How second ingredient of the technical solution adopted in the present invention solves the aseptic problem of Chinese medicine job shop, makes it satisfy Chinese medicine production hygienic requirements (meeting medicine GMP authentication):
In the Chinese medicine course of processing, need clean operating room, need air cleaning to handle, solution is: in (just on the container) top outer on the car body combination type air is installed and is handled unit and fresh air conditioner unit, heat, cool off, sterilize, sterilize, filter by the air of combination type air processing unit the toilet of this interior correspondence, make the interior corresponding toilet's cleanliness factor of car reach the pharmaceutical production hygienic requirements, there is the people to operate simultaneously inside, also will starts the fresh air conditioner unit and send new wind to guarantee personal security to the inside.Handle simultaneously carrying out air cleaning, note the pressure reduction rational Application, for example, medicine filling and package car is with respect to cover mark, coding, loading packing car internal positive pressure, and cover mark, coding, loading packing car inside are with respect to freight transportation car malleation.
Because it is again to be close to container top to install that internal container good seal performance, combination type air are handled unit, high efficiency, expense is low.
Active skylight or pipeline are opened in the steaming of Chinese crude drug, the car body top of correspondence such as frying, process, forging, and equipment such as good ventilation, dedusting, smoke abatement, cooling are installed.
The extraction of Chinese crude drug, the prepared slices of Chinese crude drugs, car body upper area for feeling pulse on the head window or pipeline such as concentrate, good air draft is installed and prevents to pollute and equipment such as cross-contamination.
Beneficial effect
(1) the Chinese medicine job shop of Yi Donging processes nearby to the planting base, now plucks, existing receives, on-the-spot chemical examination, realizes the zero distance transportation, guarantees that absolutely medicinal raw material is fresh, lossless, pollution-free.
(2), the on-the-spot decoction pieces field assay finger printing of concocting is found quality problems, in time adjusts and looks for reason, reduces the wastage of material phenomenon, avoids blindly producing.Begin quality control from the source.The on-the-spot decoction pieces of concocting is selected the packing that adapts to according to its characteristic, and adds the various information in man-hour at that time with field assay finger printing and product, and its packing decoction pieces can be avoided polluting in the circulation transit link.
(3), the GAP of every kind of medical material correspondence cultivates the base, does not repeat to set up fixed " first job shop ", sets up the Chinese medicine job shop that moves, and according to medical material collecting period difference, comes and goes touring processing in each base, has improved utilization rate of equipment and installations greatly.Greatly reduce production cost.
(4) windfall effect is: prepared slices of Chinese crude drugs industry is to realize an important step of the modernization of Chinese medicine, prepared slices of Chinese crude drugs industry modernization should be drawn close with the Chinese crude drug industrialization base, the Chinese medicine job shop that moves combines with the operation of gathering and processing of Chinese crude drug, carry out continuously, settle at one go, the production of decoction pieces, particularly cutting (is repaiied system, section) can settle at one go in the medical material production base, benefit is that medical material can be taken advantage of fresh cut slice, dry easily, remove after the drying profit (bubble) again from, cut into slices again, the losing of exsiccant more loaded down with trivial details operation and effective ingredient, (be difficult for except the preserver after some medical material section certainly, as Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus etc.); Also can reduce medical material cleans, repairs and renovate in the process the pollution of urban environment and alleviate the burden etc. of round transport.
Description of drawings
Fig. 1 is traditional medicine processing machinery tool and the package packing machine and the health check and analysis instrument of the specialty with various advanced persons of the present invention, be installed in respectively by functional requirement classification in the car body of sealing of different temperature controls, formed one to the different Chinese medicine processing special-purpose vehicle of multi-section function, these car body have been spliced and combined into Chinese medicine (natural drug) the job shop sketch map of the sealing of a mobile temperature control with the order of Chinese medicine processing process.
Schematic diagram is top view, and tractor-truck and car body are separable, and tractor-truck partly saves and do not draw, and has only drawn The car body part that the container of semitrailer carrying forms, and the floor map that is combined into by these car body.
Schematic diagram succinctly demonstrates the envelope of the temperature control of the movement that four kinds of general assembling combination forms consist of The Chinese medicine job shop that closes specifically will process certain the kind prepared slices of Chinese crude drugs and extract, only needs shown in the figure This kind of installation processing is concocted and is extracted special-purpose equipment and gets final product in the car, and increase and decrease is reflected in specially on working ability and the function Quantitatively increase and decrease with car, the increase and decrease of special-purpose vehicle can be made up mode by schematic diagram and be increased and decreased very flexibly, so one The Chinese medicine job shop of the sealing of mobile temperature control is because four kinds of combination modes can form diversified Chinese medicine and add Worker workshop flow process and scale scheme, its scale is changeable, function can be by force can a little less than, given birth to by actual conditions and Chinese medicine Production. art requires concrete the selection to determine.
Fig. 1 schematic diagram is made up of following special-purpose vehicle:
A represents: the pre-treatment special-purpose vehicles such as the cleaning of raw material, choosing are chosen, carried, lifting
B represents: softening, cutting etc. concocted special-purpose vehicle
C represents: special-purpose vehicle is concocted in oven dry, frying etc.
D represents: extract, separate, concentrate, carry air purification fresh air blower on purifying, drying, sterilization and the car body Group is carried out sterile air and is processed special-purpose vehicle.
E represents: the monitoring of hygiene and set up raw material original producton location information dedicated car
F represents: water treatment and oil burning boiler and refrigeration unit provide the Cooling and Heat Source special-purpose vehicle
G represents: leftover bits and pieces (containing sewage) is processed special-purpose vehicle
H represents: medicine materical crude slice warehouse special-purpose vehicle, negative pressure is in the L car
L represents: medicine materical crude slice packing special-purpose vehicle carries the air purification fresh air blower group and carries out the sterile air processing on the car body.
M represents: analyze the quality control special-purpose vehicle, carry the air purification fresh air blower group on the car body and carry out the sterile air processing.
N represents: contain the packing special-purpose vehicle of toilet, carry the purifying fresh air unit on the car and carry out the sterile air processing.
O represents: cover mark, coding, vanning finished product special-purpose vehicle
P represents: contain sterilize dressing cubicle and enter the passage of N car and carry the purifying fresh air unit and carry out sterile air and process special-purpose vehicle of Airshower chamber and workman
Q represents: staff canteen and bedroom special-purpose vehicle
Embodiment
In conjunction with the accompanying drawings, implement the processing of typical Fructus Lycii decoction pieces and matrimony vine capsule (extract) the present invention will be further described spatial formation and application, do not consider whether Fructus Lycii decoction pieces and capsule (extract) technology is correct.
At first, processing Fructus Lycii decoction pieces a series of device classes are installed in each special-purpose vehicle shown in Figure 1, have formed a Fructus Lycii decoction pieces and Fructus Lycii Chinese medicine job shop, below each car function of brief description with equipment the situation that is connected is installed:
A represents:
Special-purpose vehicle is chosen, carries, is promoted in the cleaning of raw material, choosing, and Fructus Lycii enters the production line special-purpose vehicle neatly; Link to each other by doorframe with B car " " word; Link to each other by pipeline with the F car, provide the water source by the F car.
B represents:
Concoct special-purpose vehicle; Link to each other by door with the C car, link to each other with the G car and carry offal.
C represents:
Concoct special-purpose vehicle; Link to each other by pipeline with the F car, provide steam by the F car; Link to each other by door with L decoction pieces packing special-purpose vehicle; Link to each other by door with D Chinese medicine extraction system-specific car, the prepared slices of Chinese crude drugs are provided.
D represents:
Chinese medicine extraction system-specific car.Carry air-treatment unit and air conditioning unit.Link to each other by door with the C car.Acceptance is from the raw material of C car.Accept the M car and analyze the finger printing quality control, carry the new blower fan group of air cleaning on the car body and carry out the sterile air processing.
E represents:
The monitoring of hygiene and set up raw material original producton location information system special-purpose vehicle.
F represents:
Water treatment and oil burning boiler and refrigeration unit provide the Cooling and Heat Source special-purpose vehicle to provide to each car by pipeline
The water and the Cooling and Heat Source that need.Draw no longer one by one on Fig. 1.
G represents:
Leftover bits and pieces (leftover bits and pieces etc.) is handled special-purpose vehicle.
H represents:
Decoction pieces warehouse special-purpose vehicle.
L represents:
Decoction pieces packing special-purpose vehicle.
M represents:
Analyze finger printing, control of quality carries the new blower fan group of air cleaning and carries out sterile air on the car body
Handle special-purpose vehicle.
N represents: contain the packing special-purpose vehicle of toilet, carry the new blower fan group of purification on the car and carry out the sterile air processing.
O represents: carry the new blower fan group of purification on cover mark, coding, vanning and the car and carry out sterile air processing special-purpose vehicle.
P represents:
Workman's sterilization is changed one's clothes and is entered the passage of N car and carry the new blower fan group of purification and carries out sterile air processing special-purpose vehicle.
Q represents:
Staff canteen and bedroom special-purpose vehicle.
Decoction pieces and finished product (decoction pieces extract) course of processing:
Decoction pieces is produced:, Fructus Lycii enters the A special-purpose vehicle from the feed(raw material)inlet, and the production line pretreatment is clean, enters B and concocts special-purpose vehicle, enters C and concocts special-purpose vehicle, enters L decoction pieces packing special-purpose vehicle, and is last, enters H decoction pieces warehouse special-purpose vehicle.
Wherein leftover bits and pieces enters the G leftover bits and pieces by the B special-purpose vehicle and handles special-purpose vehicle.
Finished product (decoction pieces extract) is produced:, decoction pieces enters D decoction pieces extraction system special-purpose vehicle, enters the packing special-purpose vehicle that N contains the toilet, carries the new blower fan group of purification on the car and carries out the sterile air processing, enters O cover mark, coding, outer package special-purpose vehicle.
The passage special-purpose vehicle that P workman sterilizes and changes one's clothes and enter the N car.
The N car just is being pressed on O outer package special-purpose vehicle.
E health inspection vehicle with set up product with the original producton location data message:
Registration native breed and plantation family information are input among the product plantation data base, carry out pesticide residues and virus and follow the tracks of the processing monitoring.
Claims (10)
1. set up the method and the application of the Chinese medicine job shop that moves, it is characterized in that its concrete technical solution is:
The traditional medicine processing machinery tool of various advanced persons' specialty and package packing machine and health are detected and analytical tool, be installed in respectively by functional requirement classification in the car body of sealing of different temperature controls, formed one to the different Chinese medicine processing special-purpose vehicle of multi-section function, to the medical material original producton location, these car body are spliced and combined into the Chinese medicine job shop of the sealing of a mobile temperature control with the order of Chinese medicine processing process; And utilize clean technology that combination type air promptly is installed on car body and handle unit and dust removal process unit, to the car body that needs the sterile working or in it space of corresponding toilet heat, cooling, sterilization, sterilization, filtration treatment, make it meet medicine GMP standard authentication, its product comprises semi-finished product and all has medical material original producton location information and finger printing.
2. method according to claim 1 is characterized in that, its concrete technical solution is:
Carrying the means of transport that container combines on tractor truck in the automotive-type and trailer apoplexy due to endogenous wind semitrailer and the semitrailer, this car by tractor-truck and container (this paper the claims car body) two parts of partly pulling carrying form, tractor-truck and car body are separable, be convenient to head and the tail " one " font butt joint between the car body, partly pull the car body of the container composition of carrying, its container of partly pulling and carrying is partable also, looks practical situation and applies in a flexible way;
" car body " be meant semi-trailer carrying container constituted;
" in the car body " in fact is meant in the container body;
" special-purpose vehicle " is meant the special-purpose vehicle that the Chinese medicine machining functions that equipment had has been installed by the internal container of tractor truck head and semi-trailer carrying;
" car body of temperature control " is to form with the insulation material transformation around being meant inner wall of container, or customize with the new material with heat preservation property, refrigeration unit installs an air-conditioner in outside, corresponding top, and at the corresponding inner temperature inductor of installing, the refrigeration unit of control outside provides needed temperature and humidity in this car body;
" spatial organization " be meant in twos container just in twos between the car body by side by side, dislocation, four kinds of " one " fonts, " fourth " font connect compound mode and spatial width extended method (the whole H connection method of adjustable ratio are turned in the space width expansion up and down from beginning to end, space width is expanded the lateral hinges connection method), but assembling combination becomes needed space;
" function combinations " is meant that the machining functions of Chinese medicine job shop also can be changed by the variation of the different process of preparing Chinese medicine special-purpose vehicle of a certain processing decoction pieces of replacing, or the process of preparing Chinese medicine equipment replacement of its inside, and other as extract, separate, concentrate, special-purpose vehicles such as purification, drying, sterilization, packing need not change, just can process by the prepared slices of Chinese crude drugs of changing the decoction pieces kind that special-purpose vehicle process of preparing Chinese medicine determined; Increase by process of preparing Chinese medicine equipment combination in different special-purpose vehicle combinations or the car body, its machining functions increases, and utilization rate of equipment and installations is high;
" sealing property " is meant the connection between the car body in twos, and at first each self-corresponding risers that will connect at two containers is opened onesize door, and door can be a sliding door, also can vertical hinged door, closing door when not connecting separately; Vertical hinged door is wanted earlier door to be opened as towards external-open, and put near pendulum (stopping) back; During connection, open separately behind the door, the door pocket of being made by insulation material is installed around door opening separately, sealing is closely fixing around door pocket and the door opening, the width of door pocket (or degree of depth of title door pocket) is put 1/2nd of distance less than two car body, the connection doorframe of being made by insulation material of putting distance of being wider than is embedded in the two car body door pockets, the effect of door pocket is and connects between the doorframe bigger contact surface and space are arranged, the purpose that leaves the space between door pocket and the connection doorframe is to eliminate the error that pendulum (stopping) brings when putting between two car body, with insulation rubber bar space good seal around the connection doorframe that embeds in the two car body door pockets and between the door pocket, by connecting doorframe two car body inner spaces are coupled together, and seal with the external world;
Vertical hinged door or the sliding door of being made by insulation material installed at two that can promptly connect doorframe in two car body the insides of correspondence as required that connecting doorframe has separately, the car body passage dual face seals that connects two connections of two door knobs on the doorframe, play buffer compartment from the effect of grade, adapt to the MGP authentication requesting.
3. space length in the method according to claim 2 and width extended method is characterized in that, its concrete technical solution is:
Spatial extended length method:
The single container length of length 12000MM, height 3000MM, width 2500MM is not enough, onesize two or three and even four container head and the tail " one " fonts can be connected, total length is 24000MM, 36000MM or 48000MM, and the medicine transmission line forms a long middle leechdom production line in enough installing;
Spatial width extended method:
With length 6000MM, height 3000MM, the data instance of width 2500MM, if single container width is not enough, can put two parallel pendulum of container (stopping), pendulum (stopping) is put the height that distance equals container, the corresponding container side elevation that will connect is transformed, 1/2 place of container side elevation disconnects, side elevation all hinges up and down, formed as seeing in our daily life that vertical hinged door revolves and turn 90 degrees, promptly one is turned over up, one is turned over down, with two blocks of rectangle sheet materials that contain insulation material of a size, length equals container length, width 500MM-1000MM, middle be used for pressing from both sides the junction of turning on two in the container by holding screw, the connected mode of junction is as revolving " H " font that turn 90 degrees, be that the two boards material is two " Shu " of H, holding screw is H "-", the centre of H press from both sides respectively two containers on turn over the junction, it is to be used for the surplus of putting to the error that container pendulum (stopping) brings when putting that the middle joint of H junction leaves the space, behind the fit sealing of H junction and horizontal steel pipe on housing between two containers fix, adjustable height, it is parallel to turn over the junction on two containers of assurance, in like manner, the connection H connection like this of turning under two containers, that face at container 2500MM width is equipped with sliding door, and the sliding door of two faces of two containers is to pushing away, just two containers have been turned over formed space closure up and down, space width has formed 8000MM;
If side elevation of container disconnects at 1/3 place, another container side elevation should disconnect at 2/3 place, all hinge up and down, connect like this and could guarantee the upper and lower height that addition respectively all equals container that turns over, adjustable ratio is whole, it is called the space width expansion turns over the whole H connection method of adjustable ratio up and down;
Also having way is exactly that to press upper hinge at container side elevation gap movable, above one in two containers hinge is installed, below another container hinge is installed, promptly an integral body is turned over up, an integral body is turned over down, turn in the process, it is movable folding to press upper hinge by gap, directly be installed to corresponding top of container and bottom, that face at container 2500MM width is equipped with sliding door, the sliding door of two faces of two containers is to pushing away, just the whole side of two containers has been turned over formed space closure up and down, space width has formed 8000MM, and it is called space width expansion lateral hinges connection method.
4. the method for the Chinese medicine job shop that foundation according to claim 2 is moved, the car body that container constituted of the semi-trailer that is wherein adopted carrying can replace with additive method, it is characterized in that its technical solution is:
" car body " can be by automobile, trailer, and the manufacturing of truck combination three major types vehicle car forms;
" in the car body " is meant in the automobile bodies body;
" special-purpose vehicle " is meant that automobile bodies body inside installed the special-purpose vehicle of the Chinese medicine machining functions that equipment had.
5. the method for the Chinese medicine job shop that foundation according to claim 2 is moved, the car body that container constituted of the semi-trailer that is wherein adopted carrying can replace with additive method, it is characterized in that its technical solution is:
Container replaces with the irregular casing that has living space, and the car body that irregular casing constituted of having living space of the semi-trailer carrying of promptly adopting replaces.
6. the method and the application of the Chinese medicine job shop that foundation according to claim 1 is moved how by medicine GMP authentication, is characterized in that its concrete technical solution is:
In (just on the container) top outer on the car body combination type air is installed and is handled unit and fresh air conditioner unit, handling unit by combination type air heats, cools off, sterilizes, sterilizes, filters this interior air, make in the compartment or toilet's cleanliness factor reaches Chinese medicine production hygienic requirements, there is the people to operate simultaneously inside, also will starts the fresh air conditioner unit and send new wind to guarantee personal security to the inside; Note the rational Application of pressure reduction;
Because it is again to be close to container top to install that internal container good seal performance, combination type air are handled unit, high efficiency, expense is low;
Active skylight or pipeline are opened in the steaming of Chinese crude drug, the car body top of correspondence such as frying, process, forging, and equipment such as good ventilation, dedusting, smoke abatement, cooling are installed;
The extraction of Chinese crude drug, the prepared slices of Chinese crude drugs, car body upper area for feeling pulse on the head window or pipeline such as concentrate, good air draft is installed and prevents to pollute and equipment such as cross-contamination.
7. the method and the application of the Chinese medicine job shop that foundation according to claim 1 is moved is characterized in that, its concrete technical solution is:
Now pluck existing receipts to the raw material original producton location, the decoction pieces of the process of preparing Chinese medicine and decoction pieces extract are found the on-the-spot corrigendum of quality problems when the field analysis finger printing.
8. method according to claim 1 and application, its product feature is:
In the raw material original producton location, raw material need not transportation, and the Chinese medicine job shop through moving is processed into decoction pieces or extract packages, and transportation is avoided polluting.
9. method according to claim 1 and application, its mode of production is characterised in that:
Traditional mode of production: job shop is fixed, and raw material is " moving ", and the product after the raw material processing is " moving ", and freight is big, the lossy and pollution of raw material, and product quality does not guarantee;
The mode of production of the present invention: job shop is " moving ", and raw material is fixed, and product is " moving ", and freight is little, and raw material does not have loss and pollution, and product quality is guaranteed.
10. method according to claim 1 and application are set up product with original producton location data message and finger printing, it is characterized in that:
The scene is carried out the pesticide residues monitoring and is carried out the general follow-up of quality control of fingerprint image, and registration native breed and plantation family information are formulated finger printing then and there and product information is attached in the packing of product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100380302A CN100446744C (en) | 2005-03-09 | 2005-03-09 | Method and application for building movable Chinese medicine processing plant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100380302A CN100446744C (en) | 2005-03-09 | 2005-03-09 | Method and application for building movable Chinese medicine processing plant |
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| Publication Number | Publication Date |
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| CN1663554A true CN1663554A (en) | 2005-09-07 |
| CN100446744C CN100446744C (en) | 2008-12-31 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2005100380302A Expired - Fee Related CN100446744C (en) | 2005-03-09 | 2005-03-09 | Method and application for building movable Chinese medicine processing plant |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101261260B (en) * | 2007-03-07 | 2011-01-12 | 中国药品生物制品检定所 | Medicine detection vehicle |
| CN102094228A (en) * | 2009-12-09 | 2011-06-15 | 鸿富锦精密工业（深圳）有限公司 | Production line |
| CN101554854B (en) * | 2009-05-19 | 2011-10-12 | 中国航空技术广州有限公司 | Combined type car system used for mobile hospital |
| CN106839180A (en) * | 2016-12-21 | 2017-06-13 | 江苏博生医用新材料股份有限公司 | A kind of clean control conveying technique |
| CN110949983A (en) * | 2019-12-25 | 2020-04-03 | 杜泽臣 | Dynamic production device and working method thereof |
| CN111196202A (en) * | 2020-01-19 | 2020-05-26 | 哈尔滨工业大学 | Mobile house planning method under unmanned technology background |
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| CN1100998A (en) * | 1993-09-28 | 1995-04-05 | 深圳市宝安区慢性病防治站 | Mobile medical health vehicle and combination method thereof |
| CN2361696Y (en) * | 1999-03-02 | 2000-02-02 | 耿洪涛 | Movable plate house capable of assembling and disassembling |
| RU2180625C1 (en) * | 2001-05-24 | 2002-03-20 | Кобзарь Евгений Маркович | Mobile food shop |
| US20040026812A1 (en) * | 2002-08-12 | 2004-02-12 | Tiy Inc. | Apparatus for bench scale tablet-making |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101261260B (en) * | 2007-03-07 | 2011-01-12 | 中国药品生物制品检定所 | Medicine detection vehicle |
| CN101554854B (en) * | 2009-05-19 | 2011-10-12 | 中国航空技术广州有限公司 | Combined type car system used for mobile hospital |
| CN102094228A (en) * | 2009-12-09 | 2011-06-15 | 鸿富锦精密工业（深圳）有限公司 | Production line |
| CN102094228B (en) * | 2009-12-09 | 2013-09-18 | 鸿富锦精密工业（深圳）有限公司 | Anodization production line |
| US8911598B2 (en) | 2009-12-09 | 2014-12-16 | Hon Hai Precision Industry Co., Ltd. | Anodizing processing line |
| CN106839180A (en) * | 2016-12-21 | 2017-06-13 | 江苏博生医用新材料股份有限公司 | A kind of clean control conveying technique |
| CN106839180B (en) * | 2016-12-21 | 2019-10-25 | 江苏博生医用新材料股份有限公司 | A kind of clean control conveying technique |
| CN110949983A (en) * | 2019-12-25 | 2020-04-03 | 杜泽臣 | Dynamic production device and working method thereof |
| CN110949983B (en) * | 2019-12-25 | 2021-05-28 | 杜泽臣 | Dynamic production device and working method thereof |
| CN111196202A (en) * | 2020-01-19 | 2020-05-26 | 哈尔滨工业大学 | Mobile house planning method under unmanned technology background |
| CN111196202B (en) * | 2020-01-19 | 2021-10-01 | 哈尔滨工业大学 | Mobile house planning method under unmanned technology background |
| CN112546253A (en) * | 2020-11-26 | 2021-03-26 | 华润三九（枣庄）药业有限公司 | Traditional Chinese medicine production environment management method |
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| CN100446744C (en) | 2008-12-31 |
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