CN1552285A - Magnetocardiogram and its analyzing method - Google Patents
Magnetocardiogram and its analyzing method Download PDFInfo
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- CN1552285A CN1552285A CNA031372163A CN03137216A CN1552285A CN 1552285 A CN1552285 A CN 1552285A CN A031372163 A CNA031372163 A CN A031372163A CN 03137216 A CN03137216 A CN 03137216A CN 1552285 A CN1552285 A CN 1552285A
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Abstract
A combined magnetocardiogram is composed of multiple magnetocardiograms which have different colors and are obtained at different positions on human chest. The mutual relation and distribution mode between different magnetocardiograms can be conveniently shown, so using it for clinic diagnosis.
Description
Technical field
The present invention relates to a kind of heart magnetic wave picture group and analytical method thereof.
Background technology
Because the electrocardiogram technology is in the technical limitation of heart disease diagnosis, and the development of weak magnetic signal measuring technique, the magnetocardiogram technology is subjected to paying close attention to widely in recent years.
Einthoven measured electrocardiogram first in 1901, formally electrocardiogram was used for clinically soon, and at present electrocardiogram has become the diagnostic techniques of the most conventional cardiovascular disease.So-called electrocardio is meant that cardiac muscle in process of excitation, produces faint depolarization (excitement) and multipole (recovery) electric current, and electrocardiogram is the variation of writing down heart volume electric current potential difference between 2 of body surfaces or two groups of electrodes.Though electrocardiogram has been a kind of mature technique, but because ecg measurement is subjected to the influence of skin and lung and thoracic tissues electrology characteristic, and can not carry out three-dimensional fix, can not detect current potential of anti-phase two dipoles or the like, therefore cardiac electrical clinical diagnosis has certain limitation.The acute myocardial infarction patient who has typical cardiac electrical figure variation according to statistics only accounts for 60% case, and the chronic coronary disease patient's of 70-85% static electrocardiogram and normal person are as broad as long.Its consequence is to have the people of 40% heart attack death not have early stage electrocardiogram medical history approximately.
Cardiac muscle its current dipole in process of excitation produces the Weak magentic-field of a pT magnitude in the space.Use superconducting quantum interference device and can measure the changes of magnetic field of cardiac muscle in excitement and recovery process, be called magnetocardiogram.Magnetocardiogram is the angle that changes from the measurement core field, the variation of electric current in the reflecting myocardium process of excitation, and it is directly relevant with electrocardio-activity, but has any different with electrocardiogram.Magnetocardiogram is untouchable, needn't consider the influence of skin surface contact electrode, because tissue is " transparent " to magnetic field, mcg-signals is not subjected to the influence of tissue yet, therefore highly sensitive in the electrocardiogram technology, mcg-signals can also position or the like the electrocardio dipole by analysis, so the magnetocardiogram technology is just developing into the new technique of cardiac diagnosis.
Magnetocardiogram and electrocardiogram relatively have following advantage:
(1). the permeability and the vacuum of tissue are close, that is tissue is transparent to magnetic field, thereby are not subjected to the interference of tissue electrology characteristic when detecting current dipole;
(2). magnetocardiogram can carry out space orientation accurately to current dipole, particularly body surface depth localization, this is that electrocardiogram is difficult to accomplish;
(3). the detection of magnetocardiogram is contactless, is not subjected to the interference of skin resistance;
(4). magnetocardiogram is suitable for the diagnosis of direct current component waveforms such as ST section, and is significant to the diagnosis of myocardial strain;
(5). magnetocardiogram can be measured opposite polarity two current dipoles, and electrocardiogram then can not be measured.
Magnetocardiogram may be applied on the electrocardiogram technology has the case diagnosis of limitation, as the diagnosis of myocardial infarction; The diagnosis of myocardial strain; To the indiscoverable heart disease diagnosis of electrocardiograms such as old myocardial infarction, myocardial ischemia; Carry out the location of heart power; The fetus magnetocardiogram measurement; And scalded patient's magnetocardiogram measurement etc.
Clinical observation is found, the angiography and the magnetocardiography that to not have the patients with coronary heart disease of ECG change to do compare, find that magnetocardiogram has the sensitivity (91%) and the specificity (84%) of height for coronary heart disease diagnosis, and can accurately judge the position (79%) of lesion vessels, need to make the number that intervention property coronary angiography is checked thereby can reduce, alleviate patient's psychosoma burden.Owing to be complete non-invasive diagnostic techniques, thereby range of application widely arranged than electrocardiogram.
In addition, magnetocardiogram also is applied to other medical domain, predicts as the cardiac risk degree to the patient before the surgical operation; Treatment is assessed to cardiovascular drugs; New drug is carried out clinical research; High-risk group's health status is estimated and application in sports medical science etc.We can say that magnetocardiogram has shown wide applications.
At present, the magnetocardiogram measuring technique is gradually improved, but the clinical diagnosis of magnetocardiogram is at the early-stage.Diagnostic method mainly comprises isomagnetic chart, eelctric dipole figure etc., but quantitatively and qualitatively judges also immaturity.The diagnostic method of magnetocardiogram and diagnostic criteria are very imperfect as yet, remain further to be studied.
Summary of the invention
Technical problem to be solved by this invention provides a kind of colored heart magnetic wave picture group and analytical method, can analyze the variation characteristic of magnetocardiogram aspect three of time, space and waveforms, time domain parameter and wave amplitude parameter that can quantitative assay heart magnetic wave picture group.
This is a kind of brand-new analytical method, might become a kind of quantitative analytical technology in the diagnosis of heart magnetic.
For solving the problems of the technologies described above, the present invention is with high temperature superconducting quantum interfering device or other magnetic-field-sensitive elements, the human body different parts obtains the magnetocardiogram waveform, represent the magnetocardiogram waveform of different parts record with different colours, the ecg wave form of the electrocardiogram lead that writes down simultaneously of basis and magnetocardiogram is aimed at stack in time with all magnetocardiogram waveforms and is formed colored heart magnetic wave picture group as time synchronizing signal again.
The time reference of the stack alignment of heart magnetic wave picture group is the maximum point of QRS ripple slope absolute value in the electrocardiogram lead.
Magnetocardiogram flat distribution map that different colours is represented and colored heart magnetic wave picture group show simultaneously on one page, are convenient to its plane distribution pattern of comparison.
Make the upper and lower envelope of colored heart magnetic wave picture group with computer software, obtain heart magnetic wave group envelope diagram, its waveform is classified, heart magnetic wave group envelope diagram is carried out the measurement and the analysis of parameter.
The method of heart magnetic wave picture group being carried out the measurement of parameter and analysis is as follows:
(1) name of magnetocardiogram waveform
Identical with electrocardiogram, the magnetocardiogram waveform is by wave components such as P, QRS, T.By the P wave group, the QRS wave group, T wave group and corresponding time domain are formed magnetocardiogram ripple group.Heart magnetic wave picture group parameter is divided into time domain parameter group and wave amplitude parameter group two large divisions.
(2) definite (see figure 1) of heart magnetic wave picture group datum mark
A. at first find out the flat section of TP, determine T ripple stop and P ripple starting point.The flat section of TP is the datum line of magnetocardiogram, and in the flat section time limit, no electrocardio-activity is not so also be in the mood for magnetic acitvity at TP.
B. along P ripple starting point (P
i), seek P ripple terminal point P to the right
t, P
tBe the separation of P ripple and the flat section of PR, P
iTo P
tPeriod is the P ripple, is the exciting magnetocardiogram that produces in atrium, at P
iTo P
tIn period, find out the maximum P of P wave group
+And the minimum P of P wave group
-
C., seek the starting point V of QRS wave group along the flat section of PR to the right
i, again along V
iSeek the stop V of QRS wave group to the right,
t, (V
tHave another name called the J point), from V
iTo V
tIn period is the QRS wave group, is the magnetocardiogram that ventricular activation produces.
D. at V
iTo V
t(QRS wave group) in the period, finds out three of the QRS wave group (or several) maximum R successively
1, R
2, R
3
E. in the QRS wave group period, find out the minimum of three (or several) QRS wave groups.If first minimum is at R
1Called after Q ripple then before is if first minimum is at R
1Called after S then after the ripple
1Ripple, two ripples called after S successively thereafter
2Involve S
3Ripple, the rest may be inferred by analogy.
Find out T ripple starting point T f. to the right, along the ST section
iAnd T ripple stop T
tQRS ripple stop J (V
t) to being the ST section between the T ripple starting point, T
iTo T
tBetween be the T ripple.T
tTo next P ripple starting point P
iBetween flat section be the flat section of TP.
(3) the time domain parameter group of heart magnetic wave picture group:
(1). τ
P: the P ripple time limit, for from P
iTo P
tBetween the P wave width;
(2). τ
PR: the PR interval, for from P
iTo V
iBetween period, comprise that P involves flat section between P ripple and QRS ripple;
(3). τ
V: the VQRS ripple time limit, for from V
iTo V
tBetween the QRS wave width;
(4). τ
ST: the ST section time limit, for from V
tPoint (J point) is to T
iBetween time period;
(5). τ
T: the T ripple time limit, for from T
iTo T
tBetween the T wave width;
(6). τ
QT: the QT interval, for from V
iTo T
tBetween time limit, comprise QRS wave group and ST-T two parts;
(7). τ
R1: R
1The ripple peak time is for from V
iTo R
1The time period of crest;
(8). τ
R2: R
2The ripple peak time is for from V
iTo R
2The time period of crest;
(9). τ
R3: R
3The ripple peak time is for from V
iTo R
3The time period of crest;
(10). τ
Q: Q ripple peak time, for from V
iTo the time period at Q wave-wave peak;
(11). τ
S2: S
2The ripple peak time is for from V
iTo S
2The time period of crest;
(12). τ
S3: S
3The ripple peak time is for from V
iTo S
3The time period of crest;
(13). τ
T+: T ripple posivtive spike peak time, for from T
iTo the time period of T ripple posivtive spike;
(14). τ
T-: T ripple negative peak peak time, for from T
iTo the time period of T ripple negative peak;
(15). τ
ST-T: the ST-T interval, for from V
t(J point) is to T
tTime period, τ
ST-TEqual τ
STWith τ
TSum.
(4) the wave amplitude parameter of heart magnetic wave picture group:
The wave amplitude parameter of heart magnetic wave picture group is unit with pT, and its witness mark datum line is the line of TP section mid point, names to be B line (Base Line).
(1) .A
P: the P wave-wave width of cloth, the P wave-wave is less, is A with the distance between P wave-wave width of cloth maximum and the wave amplitude minima
P
(2) .A
R1: R
1The wave-wave width of cloth, for from the B line to R
1The amplitude of crest;
(3) .A
R2: R
2The wave-wave width of cloth, for from the B line to R
2The amplitude of crest;
(4) .A
R3: R
3The wave-wave width of cloth, for from the B line to R
3The amplitude of crest;
(5) .A
Q: the Q wave-wave width of cloth is the amplitude to Q wave-wave peak from the B line;
(6) .A
S2: S
2The wave-wave width of cloth, for from the B line to S
2The amplitude of crest;
(7) .A
S3: S
3The wave-wave width of cloth, for from the B line to S
3The amplitude of crest;
(8) .A
T+: the positive T wave-wave width of cloth is the amplitude to positive T crest from the B line;
(9) .A
T-: the negative T wave-wave width of cloth is the amplitude to negative T crest from the B line;
(10) .W
TP: TP section mid point tranquillization field intensity amplitude is the height of the flat section of TP midpoint tranquillization field intensity, i.e. width between the envelope of B line top and below;
(11) .W
PR: PR section mid point tranquillization field intensity amplitude, i.e. width between the upper and lower envelope of PR section mid point;
(12) .W
ST: ST section mid point tranquillization field intensity amplitude, i.e. width between the upper and lower envelope of ST section mid point;
(13) .W
J: J point tranquillization field intensity amplitude, i.e. width between the upper and lower envelope of J point;
(14) .W
Tj: T ripple terminal point (is T
tPoint) tranquillization field intensity amplitude, i.e. T
tWidth between the upper and lower envelope of point.
Heart magnetic wave picture group superposes the magnetocardiogram of chest multi-section position synchronously, with the different position of different colours representative, can analyze the variation characteristic of magnetocardiogram aspect three of time, space and waveforms.This heart magnetic wave picture group can conveniently show the mutual relation and the distribution mode thereof of different parts magnetocardiogram waveform, can carry out multiparameters such as time domain parameter and wave amplitude parameter measures, be a kind of new method of magnetocardiogram clinical diagnosis, can be used as that other magnetocardiogram diagnostic methods are to be replenished.
Because heart magnetic wave picture group and Electrocardiographic relation are closer, so easily accepted by the clinicist, as a kind of new magnetocardiogram diagnostic method and standard, bigger using value and prospect are arranged clinically.
Below in conjunction with the drawings and specific embodiments the present invention is described in further detail.
Description of drawings
Fig. 1 is the name figure of magnetocardiogram waveform
Fig. 2 magnetocardiogram front measuring position figure
Fig. 3 is the flat distribution map of magnetocardiogram
Fig. 4 is colored heart magnetic wave picture group
Fig. 5 is a heart magnetic wave group envelope diagram
Fig. 6 is a routine normal person a heart magnetic wave picture group
Fig. 7 is a routine right bundle branch block patient a heart magnetic wave picture group
The specific embodiment
In order to realize the present invention, at first with high temperature superconducting quantum interfering device or other magnetic-field-sensitive elements, the human body different parts obtains the magnetocardiogram waveform.Present embodiment is measured the magnetocardiogram waveform at someone position, chest 36 place, and Fig. 2 represents the position, front that magnetocardiogram is measured, each measuring position of some expression among the figure.Fig. 3 is the magnetocardiogram that measures on 36 positions, and different colours is represented the magnetocardiogram waveform of different parts record, and present embodiment is stipulated upper right chest for green, and the bottom right chest is yellow, and upper left chest is blue, and the lower-left chest is red, and color also can be made separate stipulations.Then the different colours of Fig. 3 is represented the magnetocardiogram waveform of different parts record, the ecg wave form of the electrocardiogram lead that writes down simultaneously of basis and magnetocardiogram is as time synchronizing signal again, all magnetocardiogram waveforms are aimed at stack in time form colored heart magnetic wave picture group, as shown in Figure 4.The time reference of the stack alignment of heart magnetic wave picture group is the maximum point of QRS ripple slope absolute value in the electrocardiogram lead.
Fig. 6 is the heart magnetic wave picture group of an example with a normal person of high temperature superconducting quantum interfering device mensuration.
Make the heart magnetic wave group envelope diagram that the upper and lower envelope of the colored heart magnetic wave of Fig. 4 picture group obtains with computer software, as shown in Figure 5.Normal person and different patients' heart magnetic wave picture group is different, can classify to its waveform, and heart magnetic wave group envelope diagram is carried out the measurement and the analysis of parameter.
Identical with electrocardiogram, the magnetocardiogram waveform is by wave components such as P, QRS, T.By the P wave group, the QRS wave group, T wave group and corresponding time domain are formed magnetocardiogram ripple group.As shown in Figure 1.Heart magnetic wave picture group parameter is divided into time domain parameter group and wave amplitude parameter group two large divisions.
Before measuring heart magnetic wave picture group parameter, need to determine earlier datum mark, see Fig. 1, concrete steps are as follows:
A. at first find out the flat section of TP, determine T ripple stop and P ripple starting point.The flat section of TP is the datum line of magnetocardiogram, and in the flat section time limit, no electrocardio-activity is not so also be in the mood for magnetic acitvity at TP.
B. along P ripple starting point (P
i), seek P ripple terminal point P to the right
t, P
tBe the separation of P ripple and the flat section of PR, P
iTo P
tPeriod is the P ripple, is the exciting magnetocardiogram that produces in atrium, at P
iTo P
tIn period, find out the maximum P of P wave group
+And the minimum P of P wave group
-
C., seek the starting point V of QRS wave group along the flat section of PR to the right
i, again along V
iSeek the stop V of QRS wave group to the right,
t, (V
tHave another name called the J point), from V
iTo V
tIn period is the QRS wave group, is the magnetocardiogram that ventricular activation produces.
D. at V
iTo V
t(QRS wave group) in the period, finds out three of the QRS wave group (or several) maximum R successively
1, R
2, R
3
E. in the QRS wave group period, find out the minimum of three (or several) QRS wave groups.If first minimum is at R
1Called after Q ripple then before is if first minimum is at R
1Called after S then after the ripple
1Ripple, two ripples called after S successively thereafter
2Involve S
3Ripple, the rest may be inferred by analogy.
Find out T ripple starting point T f. to the right, along the ST section
iAnd T ripple stop T
tQRS ripple stop J (V
t) to being the ST section between the T ripple starting point, T
iTo T
tBetween be the T ripple.T
tTo next P ripple starting point P
iBetween flat section be the flat section of TP.
After finding datum mark, begin to measure heart magnetic wave picture group parameter, comprise time domain parameter group and wave amplitude parameter group.
The regulation of time domain parameter group is as follows:
(1). τ
P: the P ripple time limit, for from P
iTo P
tBetween the P wave width;
(2). τ
PR: the PR interval, for from P
iTo V
iBetween period, comprise that P involves flat section between P ripple and QRS ripple;
(3). τ
V: the QRS ripple time limit, for from V
iTo V
tBetween the QRS wave width;
(4). τ
ST: the ST section time limit, for from V
tPoint (J point) is to T
iBetween time period;
(5). τ
T: the T ripple time limit, for from T
iTo T
tBetween the T wave width;
(6). τ
QT: the QT interval, for from V
iTo T
tBetween time limit, comprise QRS wave group and ST-T two parts;
(7). τ
R1: R
1The ripple peak time is for from V
iTo R
1The time period of crest;
(8). τ
R2: R
2The ripple peak time is for from V
iTo R
2The time period of crest;
(9). τ
R3: R
3The ripple peak time is for from V
iTo R
3The time period of crest;
(10). τ
Q: Q ripple peak time, for from V
iTo the time period at Q wave-wave peak;
(11). τ
S2: S
2The ripple peak time is for from V
iTo S
2The time period of crest;
(12). τ
S3: S
3The ripple peak time is for from V
iTo S
3The time period of crest;
(13). τ
T+: T ripple posivtive spike peak time, for from T
iTo the time period of T ripple posivtive spike;
(14). τ
T-: T ripple negative peak peak time, for from T
iTo the time period of T ripple negative peak;
(15). τ
ST-T: the ST-T interval, for from V
t(J point) is to T
tTime period, τ
ST-TEqual τ
STWith τ
TSum.
According to the method described above, to 30 routine normally the time domain parameter measurement result such as the tables one (first group of age is 20 years old-49 years old, and second group of age is 50 years old-70 years old) of Chinese male heart magnetic wave picture groups:
The time domain parameter measurement result of table 1 30 routine normal Chinese's heart magnetic wave picture groups
Table?1?Parameters?of?time?domain?in?MCG?wave?sets[M(SD)]
Times(ms) Group?1(n＝23) Group?2(n＝7)
τ
P 66.02(12.56) 67.08(15.98)
τ
PR 161.92(26.06) 145.06(41.63)
τ
V 95.19(18.19) 93.41(22.39)
τ
ST 100.25(25.58) 116.43(25.41)
τ
T 160.07(21.90) 155.84(24.05)
τ
QT 359.58(27.60) 360.83(31.44)
τ
R1 17.17(4.30) 25.83(16.61)
τ
R2 43.42(9.66) 47.10(16.17)
τ
R3 74.25(12.76) 78.13(25.67)
τ
Q 21.52(10.35) 28.07(17.40)
τ
S2 46.41(10.35) 51.84(14.90)
τ
S3 71.84(12.00) 73.69(16.37)
τ
T+ 292.49(23.02) 299.39(20.35)
τ
T- 288.28(23.09) 293.42(18.35)
The regulation of wave amplitude parameter group is as follows:
The wave amplitude parameter of heart magnetic wave picture group is unit with pT, and its witness mark datum line is the line of TP section mid point, names to be B line (Base Line).
(1) .A
P: the P wave-wave width of cloth, the P wave-wave is less, is A with the distance between P wave-wave width of cloth maximum and the wave amplitude minima
P
(2) .A
R1: R
1The wave-wave width of cloth, for from the B line to R
1The amplitude of crest;
(3) .A
R2: R
2The wave-wave width of cloth, for from the B line to R
2The amplitude of crest;
(4) .A
R3: R
3The wave-wave width of cloth, for from the B line to R
3The amplitude of crest;
(5) .A
Q: the Q wave-wave width of cloth is the amplitude to Q wave-wave peak from the B line;
(6) .A
S2: S
2The wave-wave width of cloth, for from the B line to S
2The amplitude of crest;
(7) .A
S3: S
3The wave-wave width of cloth, for from the B line to S
3The amplitude of crest;
(8) .A
T+: the positive T wave-wave width of cloth is the amplitude to positive T crest from the B line;
(9) .A
T-: the negative T wave-wave width of cloth is the amplitude to negative T crest from the B line;
(10) .W
TP: TP section mid point tranquillization field intensity amplitude is the height of the flat section of TP midpoint tranquillization field intensity, i.e. width between the envelope of B line top and below;
(11) .W
PR: PR section mid point tranquillization field intensity amplitude, i.e. width between the upper and lower envelope of PR section mid point;
(12) .W
ST: ST section mid point tranquillization field intensity amplitude, i.e. width between the upper and lower envelope of ST section mid point;
(13) .W
J: J point tranquillization field intensity amplitude, i.e. width between the upper and lower envelope of J point;
(14) .W
Tj: T ripple terminal point (is T
tPoint) tranquillization field intensity amplitude, i.e. T
tWidth between the upper and lower envelope of point.
According to the method described above, to 30 routine normally the wave amplitude parametric measurement result such as the tables two (first group of age is 20 years old-49 years old, and second group of age is 50 years old-70 years old) of Chinese male heart magnetic wave picture groups:
The wave amplitude parametric measurement result of table 2 30 routine normal Chinese's heart magnetic wave picture groups
Table?2.Parameters?of?intensity?domain?in?MCG?wave?sets[M(SD)]
Intensity(pT) Group?1(n＝23) Group?2(n＝7)
A
P 1.29(0.89) 1.59(1.14)
A
R1 8.69(4.40) 8.27(6.43)
A
R2 46.12(23.67) 34.65(23.38)
A
R3 8.73(4.65) 3.71(1.65)
A
Q 19.00(7.16) 17.03(5.56)
A
S2 18.57(11.75) 14.79(6.07)
A
S3 12.59(6.65) 10.93(4.95)
A
T+ 9.29(5.10) 4.68(1.87)
A
T- 7.11(4.00) 5.41(2.16)
W
J 3.39(1.36) 2.43(1.18)
W
PR 4.53(1.90) 2.57(1.14)
W
ST 2.36(1.11) 2.01(1.01)
W
Tj 1.95(0.92) 1.40(0.59)
The parameter area of heart patient's heart magnetic wave picture group waveform departs from the above-mentioned parameter value.
By comparing normal person and patient's heart magnetic wave picture group, it is ill whom can be judged.
Fig. 7 is the heart magnetic wave picture group of an example with the right bundle branch block patient of high temperature superconducting quantum interfering device mensuration, with Fig. 6 normal person's heart magnetic wave picture group comparison, can judge that prescription on individual diagnosis person is ill.
As seen from Figure 7, right bundle branch block patient's heart magnetic wave picture group shows R
2Decreased amplitude, S
3Wave amplitude increases, and QRS time limit broadening is especially with S
3Time limit broadening, double T ripple appears in the T ripple, T ripple negative peak disappears.
Claims (9)
1. heart magnetic wave picture group, with high temperature superconducting quantum interfering device or other magnetic-field-sensitive elements, the human body different parts obtains the magnetocardiogram waveform, it is characterized in that: the magnetocardiogram waveform of representing the different parts record with different colours, the ecg wave form of the electrocardiogram lead that writes down simultaneously of basis and magnetocardiogram is aimed at stack in time with all magnetocardiogram waveforms and is formed colored heart magnetic wave picture group as time synchronizing signal again.
2. according to the described heart magnetic wave of claim 1 picture group, it is characterized in that: the time reference of the stack alignment of heart magnetic wave picture group is the maximum point of QRS ripple slope absolute value in the electrocardiogram lead.
3. according to the described heart magnetic wave of claim 1 picture group, it is characterized in that: magnetocardiogram flat distribution map that different colours is represented and colored heart magnetic wave picture group show on one page simultaneously.
4. according to the described heart magnetic wave of claim 1 picture group, it is characterized in that: make the upper and lower envelope of colored heart magnetic wave picture group with computer software, obtain heart magnetic wave group envelope diagram.
5. according to the described heart magnetic wave of claim 4 picture group, it is characterized in that: its waveform is classified, heart magnetic wave group envelope diagram is carried out the measurement and the analysis of parameter.
6. the analytical method of a heart magnetic wave picture group as claimed in claim 1 is characterized in that heart magnetic wave picture group is carried out the measurement and the analysis of parameter, may further comprise the steps:
A. the name of magnetocardiogram waveform
Identical with electrocardiogram, the magnetocardiogram waveform is by wave components such as P, QRS, T.By the P wave group, the QRS wave group, T wave group and corresponding time domain are formed magnetocardiogram ripple group.Heart magnetic wave picture group parameter is divided into time domain parameter group and wave amplitude parameter group two large divisions;
B. heart magnetic wave picture group datum mark determines;
C. stipulate the time domain parameter group of heart magnetic wave picture group;
D. stipulate the wave amplitude parameter of heart magnetic wave picture group.
7. according to the analytical method of the described heart magnetic wave of claim 6 picture group, it is characterized in that: the determining of described heart magnetic wave picture group datum mark may further comprise the steps:
A. at first find out the flat section of TP, determine T ripple stop and P ripple starting point, the flat section of TP is the datum line of magnetocardiogram, and in the flat section time limit, no electrocardio-activity is not so also be in the mood for magnetic acitvity at TP;
B. along P ripple starting point P
iSeek P ripple terminal point P to the right,
t, P
tBe the separation of P ripple and the flat section of PR, P
iTo P
tPeriod is the P ripple, is the exciting magnetocardiogram that produces in atrium, at P
iTo P
tIn period, find out the maximum P of P wave group
+And the minimum P of P wave group
-
C., seek the starting point V of QRS wave group along the flat section of PR to the right
i, again along V
iSeek the stop V of QRS wave group to the right,
t, V
tHave another name called the J point, from V
iTo V
tIn period is the QRS wave group, is the magnetocardiogram that ventricular activation produces;
D. at V
iTo V
t, promptly the QRS wave group is found out three or several maximum R of QRS wave group in the period successively
1, R
2, R
3
E. in the QRS wave group period, find out the minimum of three or several QRS wave groups, if first minimum is at R
1Called after Q ripple then before is if first minimum is at R
1Called after S then after the ripple
1Ripple, two ripples called after S successively thereafter
2Involve S
3Ripple, the rest may be inferred by analogy;
Find out T ripple starting point T f. to the right, along the ST section
iAnd T ripple stop T
t, QRS ripple stop J (V
t) to being the ST section between the T ripple starting point, T
iTo T
tBetween be the T ripple.T
tTo next P ripple starting point P
iBetween flat section be the flat section of TP.
8. according to the analytical method of the described heart magnetic wave of claim 6 picture group, it is characterized in that: the time domain parameter group of heart magnetic wave picture group is:
(1). τ
P: the P ripple time limit, for from P
iTo P
tBetween the P wave width;
(2). τ
PR: the PR interval, for from P
iTo V
iBetween period, comprise that P involves flat section between P ripple and QRS ripple;
(3). τ
V: the QRS ripple time limit, for from V
iTo V
tBetween the QRS wave width;
(4). τ
ST: the ST section time limit, for from V
tPoint (J point) is to T
iBetween time period;
(5). τ
T: the T ripple time limit, for from T
iTo T
tBetween the T wave width;
(6). τ
QT: the QT interval, for from V
iTo T
tBetween time limit, comprise QRS wave group and ST-T two parts;
(7). τ
R1: R
1The ripple peak time is for from V
iTo R
1The time period of crest;
(8). τ
R2: R
2The ripple peak time is for from V
iTo R
2The time period of crest;
(9). τ
R3: R
3The ripple peak time is for from V
iTo R
3The time period of crest;
(10). τ
Q: Q ripple peak time, for from V
iTo the time period at Q wave-wave peak;
(11). τ
S2: S
2The ripple peak time is for from V
iTo S
2The time period of crest;
(12). τ
S3: S
3The ripple peak time is for from V
iTo S
3The time period of crest;
(13). τ
T+: T ripple posivtive spike peak time, for from T
iTo the time period of T ripple posivtive spike;
(14). τ
T-: T ripple negative peak peak time, for from T
iTo the time period of T ripple negative peak;
(15). τ
ST-T: the ST-T interval, for from V
t(J point) is to T
tTime period, τ
ST-TEqual τ
STWith τ
TSum.
9. according to the analytical method of the described heart magnetic wave of claim 6 picture group, it is characterized in that: the wave amplitude parameter of heart magnetic wave picture group is unit with pT, and its witness mark datum line is the line of TP section mid point, names the line into B, and the wave amplitude parameter of heart magnetic wave picture group is:
(1) .A
P: the P wave-wave width of cloth, the P wave-wave is less, is A with the distance between P wave-wave width of cloth maximum and the wave amplitude minima
P
(2) .A
R1: R
1The wave-wave width of cloth, for from the B line to R
1The amplitude of crest;
(3) .A
R2: R
2The wave-wave width of cloth, for from the B line to R
2The amplitude of crest;
(4) .A
R3: R
3The wave-wave width of cloth, for from the B line to R
3The amplitude of crest;
(5) .A
Q: the Q wave-wave width of cloth is the amplitude to Q wave-wave peak from the B line;
(6) .A
S2: S
2The wave-wave width of cloth, for from the B line to S
2The amplitude of crest;
(7) .A
S3: S
3The wave-wave width of cloth, for from the B line to S
3The amplitude of crest;
(8) .A
T+: the positive T wave-wave width of cloth is the amplitude to positive T crest from the B line;
(9) .A
T-: the negative T wave-wave width of cloth is the amplitude to negative T crest from the B line;
(10) .W
TP: TP section mid point tranquillization field intensity amplitude is the height of the flat section of TP midpoint tranquillization field intensity, i.e. width between the envelope of B line top and below;
(11) .W
PR: PR section mid point tranquillization field intensity amplitude, i.e. width between the upper and lower envelope of PR section mid point;
(12) .W
ST: ST section mid point tranquillization field intensity amplitude, i.e. width between the upper and lower envelope of ST section mid point;
(13) .W
J: J point tranquillization field intensity amplitude, i.e. width between the upper and lower envelope of J point;
(14) .W
Tj: T ripple terminal point (is T
tPoint) tranquillization field intensity amplitude, i.e. T
tWidth between the upper and lower envelope of point.
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|---|---|---|---|
| CNA031372163A CN1552285A (en) | 2003-05-26 | 2003-05-26 | Magnetocardiogram and its analyzing method |
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ID=34323529
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| CN100581453C (en) * | 2008-09-12 | 2010-01-20 | 北京大学 | Determination method of extreme point of magnetocardiogram measurement area |
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| CN103142223B (en) * | 2011-12-07 | 2015-02-18 | 同济大学 | Heart magnetic signal processing method based on extreme value difference |
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| US9451901B2 (en) | 2012-07-13 | 2016-09-27 | Illya Anatoliiovych Chaykovskyy | Method and device for evaluation of myocardial damages based on the current density variations |
| CN109922725A (en) * | 2016-11-04 | 2019-06-21 | 艾森蒂亚股份有限公司 | Computer implemented ECG data processing method |
| CN109922725B (en) * | 2016-11-04 | 2022-04-01 | 艾森蒂亚股份有限公司 | Computer-implemented electrocardiogram data processing method |
| CN113974576A (en) * | 2021-12-23 | 2022-01-28 | 北京航空航天大学杭州创新研究院 | Sleep quality monitoring system and monitoring method based on magnetocardiogram |
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