CN1416785A - Contraceptive sponge set inside vagina - Google Patents
Contraceptive sponge set inside vagina Download PDFInfo
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- CN1416785A CN1416785A CN 02148022 CN02148022A CN1416785A CN 1416785 A CN1416785 A CN 1416785A CN 02148022 CN02148022 CN 02148022 CN 02148022 A CN02148022 A CN 02148022A CN 1416785 A CN1416785 A CN 1416785A
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Abstract
The present invention relates to one kind of female's contraceptive utensil, espcially contraceptive sponge set in vagina and its preparation and using method. Solution of medicine with the functions of contraception, disinfection, preventing disease, nourishing, amendment and lubrication is absorbed to hydrophilic polyurethane sponge to produce the contraceptive sponge, which is sealed and packed. When used, the contraceptive sponge is set at the bottom of vegina for 24 hours. It can chock the uterine orifice to reach the effect of contraception and the slowly released medicine may be absorbed by the capillary vessels in vagina and uterine to reach the effects of killing sperm, sterilizing, regulating emmenia, etc.
Description
Technical field
A kind of female contraceptive devices tool of the built-in contraceptive sponge of vagina of the present invention relates to the preparation method and the using method of a kind of contraceptive sponge product, product, belongs to medical domain.Contraceptive sponge places vagina bottom to enter the uterus to stop sperm, effect such as can have spermicide, sterilization, sterilization, diseases prevention, nutrition, conditioning concurrently or moisten.
Background technology
The development of contraception means mainly contains: sterilization operation, oral contraceptive, contraception pin, intrauterine device (IUD), condom, female condom, contraceptive membrane etc. so far.
A large amount of research and facts have proved that said method cuts both ways.Though sterilization operation safety needs operation, and causes irreversible injury; Intrauterine device (IUD) and condom are the safest contraceptive devices, yet the former will be through operation, and foreign body places for a long time and causes the generation of hysteromyoma very at high proportion in the body; The latter and female condom, contraceptive membrane etc., because must settle before sexual intercourse, its use can be made troubles, its material is selected difficult point especially, should have soft comfortable and solid, difficult dissolving or damaged, free of contamination characteristics concurrently; And the life-time service of medicines such as oral contraceptive, contraception pin can have an adverse effect to user is healthy, for example, suffers from breast cancer after using the women's federation of medicine or injection to improve the middle age, the risk of uterus carcinoma.
Above-mentioned various contraception means generally all are main purpose with the contraception, and effects such as less consideration sterilization, sterilization, conditioning, even condom, contraceptive membrane portability small amounts of medicament, it really acts on very little.
Simultaneously, how with required medicine fixed point, quantitative, slow release, and store long period of time, thereby reach the problem that required prevention, therapeutic effect is medically common concern in the desired position.
Summary of the invention
The object of the present invention is to provide and a kind ofly can be positioned over intravaginal contraceptive sponge in advance, thereby can be when blocking uterus inlet and reaching contraceptive effect, slowly discharge effective drug solution within a certain period of time, the part medicine can progressively absorb by the blood capillary in vagina and uterus, this contraceptive sponge should conveniently insert and take out, soft comfortable, cracky, pollution-free not, the characteristic and the dosage of the structure of contraceptive sponge and the drug solution of required absorption adapt.
Purpose of the present invention can be achieved through the following technical solutions: be the solution absorption that contains medicine in the polyurethanes sponge of a certain size and shape, make contraceptive sponge, and airtight package, contraceptive sponge can place the vagina bottom, reaching contraceptive effect, the described solution that contains medicine is the medicine dissolution that has contraception, sterilization, sterilization, diseases prevention, nutrition, conditioning or moisten effect formulated solution in water.
Wherein, sponge is shaped as cylinder, and diameter 3-7.5 centimetre, thick 2-5 centimetre, every centimetre has 20 to 100 loculuses in the sponge, and density did not restrain tensile force at least 1.44 kg/cm for every cubic centimetre 0.03 at least when described sponge absorbed water
2The nearly radiused edges of a cylindrical end face is provided with two relative otch, and incision length 1-3 centimetre, can stretch into a finger at least, the circular arc two ends that the cylindrical end face of sponge shape of the present invention is relative respectively are embedded with rope or line forms latch closure, are beneficial to tractive.Depression is left on perhaps described cylindrical plane, can make things convenient for push-and-pull.
On the basis of technique scheme, the built-in contraceptive sponge of vagina of the present invention rises the contraceptive efficacy except seal orifice of uterus because of it, can add different medicaments in solution and makes contraceptive sponge that other therapeutical effect be arranged.Drug solution contains one or more in spermaticide, estrogen, acid, cleanout fluid, Anti-virus agent, antimicrobial drug, the emmenagogue etc., for example, adds spermaticide and make contraceptive sponge have the spermicide effect concurrently in solution; In solution, add estrogen and have the estrogen replacement therapy effect; In solution, add acid and have the vagina of adjusting PH effect; In solution, add abstergent reagent and have the effect of cleaning vagina; In solution, add Anti-virus agent and have the antiviral curative effect; In solution, add antimicrobial drug and have sterilization, sterilization, prevent and treat the effect of vaginal infection; In solution, add emmenagogue and have regulating menstruation, the effect of treatment dysmenorrhea.
The built-in contraceptive sponge manufacture method of vagina of the present invention is as follows: making and the processing of (1) sponge: that Hdyrophilic polyurethane prepolymer, toluene di-isocyanate(TDI) (TDI), water, the surfactant of being made by the TDI derivant is polymerized is nontoxic, do not have smell, aseptic, sponge has no side effect, according to proportion, tensile force, water absorption, chamber size and the shape of required sponge and the needs of polymer architecture, add suitable water and surfactant, the control reaction condition is produced sponge; (2) carry out cutting process according to the contraceptive sponge required form; (3) preparation of solution: according to the purposes of designed contraceptive sponge, determine prescription, select medicine for use, after the weighing medicine is dissolved in deionized water, be mixed with the solution of different purposes, the PH of solution is 4 to 6; (4) sponge is dipped in the solution,, makes contraceptive sponge with abundant absorbent solution, in the contraceptive sponge of making, partially liq can be released with the extruding of sponge, and partially liq does not discharge with the extruding of sponge, total releasable liquid accounts for 5% to 50% of total amount of liquid; (5) sterilization back airtight package.
The built-in contraceptive sponge using method of vagina of the present invention is as follows: (1) is inserted: remove airtight outer package, finger stretches into contraceptive sponge one end-grain cutting mouth or latch closure or depression, the other end upwards, contraceptive sponge is pushed the bottom along vagina, sponge is sealed uterus inlet immediately, can stop sperm to enter the uterus, and the part solution in the sponge is with inserting, take out and moving and progressively discharge, flow into positions such as vagina, uterus, wherein part progressively is absorbed into blood by blood capillary; (2) contraceptive sponge can be placed at most 24 hours in vivo, and the postcoital contraception sponge is minimum in vivo should place 6 hours; (3) take out: finger is held outer end otch or latch closure or depression, gently contraceptive sponge is pulled out.
On the basis of technique scheme, the use of the built-in contraceptive sponge of vagina of the present invention can be implemented simultaneously with other contraception means, and to improve safety, other contraception means comprise men's contraceptive device, safe period, oral contraceptive etc.
The superiority of the built-in contraceptive sponge of vagina of the present invention is, is a kind of contraception means that can be free to arrange by the women, can place intravaginal in advance, do not influence the sexual intercourse process, avoids fortuitous event to take place; Safe in utilization comfortable, have no side effect; Material is solid reliable, cleanliness without any pollution; Except blocking smart ovum combination, also can have spermicide, sterilization, sterilization, diseases prevention, nutrition, conditioning or moisten effect; Can with other means Joint Implementation of practising contraception, further improve contraception efficient.
Description of drawings
Accompanying drawing 1, the outside drawing of the built-in contraceptive sponge of vagina.
Accompanying drawing 2 is to accompanying drawing 4, the bottom face view of the built-in contraceptive sponge of vagina, wherein,
Accompanying drawing 2, end face have the built-in contraceptive sponge of the vagina of otch.
Accompanying drawing 3, end face have the built-in contraceptive sponge of vagina of rope or wire loop button.
Accompanying drawing 4, end face have the built-in contraceptive sponge of the vagina of depression.
Wherein
The cylindrical end face of 1-; The cylindrical cylinder of 2-; The 3-otch; 4-rope or wire loop; The 5-depression.
The specific embodiment
Embodiment one:
Outside drawing as the built-in contraceptive sponge of Fig. 1 vagina, the built-in contraceptive sponge of vagina of the present invention is containing the solution absorption of medicine in cylindrical polyurethanes sponge, make contraceptive sponge, and airtight package, contraceptive sponge can place the vagina bottom, to reach contraceptive effect, the described solution of medicine that contains will be for having contraception, sterilization, sterilization, diseases prevention, nutrition, conditioning or the moist medicine dissolution that acts in water.Have spermicide and disinfective action as the built-in contraceptive sponge of the vagina of Fig. 2 present embodiment.Present embodiment adopts the built-in contraceptive sponge of vagina of lateral plan such as accompanying drawing 2, and the diameter of cylinder sponge is 5.6 centimetres, every centimetre of 25 loculuses, every square centimeter 0.045 gram of density when sponge does not absorb water, sponge dry weight 1.3 grams.
The manufacture method of present embodiment is:
The first step, making of sponge and processing: by TDI derive the polyurethane prepolymer that contains hydrophilic group that forms and toluene di-isocyanate(TDI) reaction, add suitable water and surfactant, the control reaction condition, produce nontoxic, do not have smell, aseptic, the sponge that has no side effect; Carry out cutting process according to the contraceptive sponge required form then.
Second step, the preparation of drug solution: select for use medicine that the medicine of spermicide and disinfective action is arranged, be dissolved in deionized water after the weighing.
The 3rd step was dipped in sponge in the solution, with abundant absorbent solution, made contraceptive sponge, and the contraceptive sponge quality of making is 7.35 grams.
The 4th step, sterilization back airtight package.
During use, remove airtight outer package earlier, finger stretches into contraceptive sponge one end-grain cutting mouth, and this end upwards pushes the bottom with contraceptive sponge along vagina; Sponge will be sealed the uterus inlet immediately, can stop sperm to enter the uterus, part solution in the sponge with inserting, take out and moving and progressively discharges, flow into positions such as vagina, uterus, wherein part progressively is absorbed into blood by blood capillary, contraceptive sponge can be placed at most 24 hours in vivo, and the postcoital contraception sponge is minimum in vivo should place 6 hours; During taking-up, finger is held outer end otch or latch closure or depression, gently contraceptive sponge is pulled out.
The contraception safety of present embodiment is 90%, and in order to improve safety, the use of the built-in contraceptive sponge of vagina of the present invention can be implemented simultaneously with other contraception means such as men's contraceptive device, safe period, oral contraceptives.
Embodiment two:
As Fig. 3 end face the rope or the built-in contraceptive sponge of vagina of wire loop button are arranged, the built-in contraceptive sponge of the vagina of present embodiment has the effect of treatment dysmenorrhea.Sponge dry weight 1.9 grams.In the preparation of drug solution, adopt the medicine that regulating menoxenia is arranged.Heavy 6 grams are equivalent to 30% of saturated water adsorptive value after the sponge absorbent solution, in use, have 4.1 gram solution to be released.During use, remove airtight outer package earlier, finger stretches into contraceptive sponge one end ring button, and this end upwards pushes the bottom with contraceptive sponge along vagina.The built-in contraceptive sponge of vagina of suggestion present embodiment is being slept preceding or menstruation arrives to be placed in preceding 12 hours vagina.
Embodiment three,
As Fig. 4 end face the built-in contraceptive sponge of vagina of depression is arranged, the built-in contraceptive sponge of the vagina of present embodiment has the effect of estrogen replacement therapy.The sponge preparation is as embodiment two.Contain the estrogens medicine in the drug solution, thickening agent, disinfectant etc., solution PH is 4.5.After the sponge absorbent solution, can not discharge solution is 20 grams, and can discharge solution is 2 grams.During use, remove airtight outer package earlier, finger stretches into contraceptive sponge one concave end, and this end upwards pushes the bottom with contraceptive sponge along vagina.The present embodiment product can use secondary weekly or follow the doctor's advice.
Embodiment four
The built-in contraceptive sponge of the vagina of present embodiment has the effect of anti-inflammation.The sponge preparation is as embodiment two.Contain broad spectrum antibiotic in the drug solution.In the use, broad spectrum antibiotic will be covered with positions such as vagina, uterus, and regulate PH to 4.0, continue to play bactericidal action.And when taking out, intravaginal impurity can be taken out of, play cleaning action.
The present embodiment product uses best at night, can alleviate symptoms such as scratching where it itches, stimulate, ache.
The present embodiment product used once in 24 hours, and whenever next used seven days continuously.
Claims (9)
1, the built-in contraceptive sponge of a kind of vagina, it comprises in totally enclosed outer package, the packing can place intravaginal sponge, be absorbed in the solution that contains medicine in the sponge, it is characterized in that, described sponge is a Hdyrophilic polyurethane class elastomeric polymer, and the described solution that contains medicine is to have the solution that contraception, sterilization, sterilization, diseases prevention, nutrition, conditioning or the moist medicine dissolution that acts on are prepared in water.
2, the built-in contraceptive sponge of vagina according to claim 1, it is characterized in that, described sponge is shaped as cylinder, diameter 3-7.5 centimetre, thickness 2-5 centimetre, every cubic centimetre has 20 to 100 loculuses in the sponge, density was not less than every cubic centimetre 0.03 gram when described sponge absorbed water, and tensile force is not less than 1.44 kg/cm
2
3, the built-in contraceptive sponge of vagina according to claim 2 is characterized in that, the nearly radiused edges of described cylindrical end face place is provided with two relative otch, and 1 to 3 centimetre of incision length can stretch into a finger at least.
4, the built-in contraceptive sponge of vagina according to claim 2 is characterized in that, the circular arc two ends that described cylindrical end face is relative respectively are embedded with rope or line forms latch closure.
5, the built-in contraceptive sponge of vagina according to claim 2 is characterized in that, depression is left on described cylindrical plane.
6, the built-in contraceptive sponge of vagina according to claim 1, its manufacture method, making and the processing of (1) sponge: that Hdyrophilic polyurethane prepolymer, toluene di-isocyanate(TDI), water, the surfactant of being made by the TDI derivant is polymerized is nontoxic, do not have smell, aseptic, sponge has no side effect; (2) carry out cutting process according to the contraceptive sponge required form; (3) solution preparation: according to the purposes of designed contraceptive sponge, determine prescription, select medicine for use, be dissolved in deionized water after the weighing, be mixed with solution, the PH of solution is 4 to 6; (4) sponge is dipped in the solution, fully absorbent solution is made contraceptive sponge, and in the contraceptive sponge of making, partially liq can be released with the extruding of sponge, and partially liq does not discharge with the extruding of sponge, total releasable liquid accounts for 5% to 50% of total amount of liquid; (5) sterilization back airtight package.
7, the built-in contraceptive sponge of vagina according to claim 1 is characterized in that described drug solution contains one or more in spermaticide, estrogen, acid, cleanout fluid, Anti-virus agent, antimicrobial drug, the emmenagogue.
8, the built-in contraceptive sponge of vagina according to claim 1, its using method: (1) is inserted: remove airtight outer package, finger stretches into contraceptive sponge one end-grain cutting mouth or latch closure or depression, and contraceptive sponge is pushed the bottom along vagina, seals the uterus inlet; (2) contraceptive sponge standing time in vivo: can place at most 24 hours, the postcoital contraception sponge is no less than 6 hours in vivo standing time; (3) take out: finger is held outer end otch or latch closure or depression, and contraceptive sponge is pulled out.
9, the built-in contraceptive sponge of vagina according to claim 1 is characterized in that, described contraceptive device can be implemented simultaneously with other contraception means, and described other contraception means comprise men's contraceptive device, safe period, oral contraceptive.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02148022 CN1416785A (en) | 2002-10-21 | 2002-10-21 | Contraceptive sponge set inside vagina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02148022 CN1416785A (en) | 2002-10-21 | 2002-10-21 | Contraceptive sponge set inside vagina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1416785A true CN1416785A (en) | 2003-05-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02148022 Pending CN1416785A (en) | 2002-10-21 | 2002-10-21 | Contraceptive sponge set inside vagina |
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| Country | Link |
|---|---|
| CN (1) | CN1416785A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103007428A (en) * | 2012-12-31 | 2013-04-03 | 胥永贵 | Vagina and rectum expansion drug built-in body |
| CN104546267A (en) * | 2015-01-13 | 2015-04-29 | 安徽农业大学 | Extrauterine contraception device for dogs and contraception method thereof |
| CN106821585A (en) * | 2017-01-26 | 2017-06-13 | 健务（上海）生物科技有限公司 | Novel contraceptive medical instrument |
-
2002
- 2002-10-21 CN CN 02148022 patent/CN1416785A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103007428A (en) * | 2012-12-31 | 2013-04-03 | 胥永贵 | Vagina and rectum expansion drug built-in body |
| CN104546267A (en) * | 2015-01-13 | 2015-04-29 | 安徽农业大学 | Extrauterine contraception device for dogs and contraception method thereof |
| CN104546267B (en) * | 2015-01-13 | 2017-01-04 | 安徽农业大学 | Birth control device and method of birth control thereof outside a kind of dog palace |
| CN106821585A (en) * | 2017-01-26 | 2017-06-13 | 健务（上海）生物科技有限公司 | Novel contraceptive medical instrument |
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