Background technology
People's normal body temperature is 37 ℃ (98.6 °F).Drop to 36 degree when following at body temperature, the clinician calls hypothermia to this state.Except the hypothermia degree is a kind of surgical method of having a mind to control, outside the rareness disposal of protecting patient's (as happy dirty and some neural operation), general hypothermia is regarded as disadvantageous, uncontrolled, the unintentional side effect on a kind of medical treatment.But, recover after surgery that hypothermic generation can be up to 60-70% in the ward.Hypothermic outer symptom is to shake and discomfort, and this state can cause other complication.
The postoperative hypothermia is known several factors.The cold patient's loses heat that makes of operating room.The temperature of most of cold surery chamber keeps below normal room temperature, generally keeps 20 ℃ maximum temperature.The patient did not have clothes when another factor was operation.The patient at most only wears gossamery robe in the cold surery chamber of being everlasting, in some cases, patient is mainly exposing in the operation for a long time.Being added to the fluid on the health such as the evaporation of iodine makes the patient further lose heat.The heat exchange of exposing between important organ and the surrounding at the health of operating on is another situation of losing heat.These factors cause the rate hypothermic occurred frequently of patient's postoperative.
A hypothermic major reason is before operation, neutralizes and then carry out venous transfusion to the patient.For example, before use in the blood products of 4 ℃ of cold preservations in ice chest.Resemble other fluid such as saline or glucose and store down, approximately than low 17 ℃ of body temperature in room temperature (20 ℃).When human body injects cold fluid, human body must be the cost acting to sacrifice other function, makes new fluid reach the temperature of people's body running.In doing so, human body temperature drops under the original temperature, and this temperature reduction amount depends on injects fluidic amount and temperature.Inject a large amount of or the very low fluid of temperature can make patient temperature descend the several years, thereby even when not having other factors, also can bring out the hypothermia phenomenon.This phenomenon is not only the old people but also very common in young patient.Therefore, injecting blood and other venous transfusion is the main inducing of the hypothermia problem of postoperative patient.
Put forth effort on the haemoheater of use owing to recognize this problem, medical circle at preheating blood before patient infusion blood always.Yet haemoheater in the past is not the satisfied solution of this problem.At first, though existing haemoheater heating blood before input, blood still is being lower than 37-38 ℃ the temperature input that human body keeps.This is because the heat loss of preheating blood on the pipeline line between from the heater to the input point, and this route gives out heat to the surrounding of lower temperature.If it is rate of flow of fluid is low, just big to the time heat loss that exposes between the input point at heater.
Most of prior art fluid heater is limited in the scope that heating region and input point are separated, and thermal source and venipuncture point are separated the length of an intravenous tube.Fluid temperature on the pipe that does not heat descends, and makes the fluid of heating that a higher original temperature must be arranged.Yet the fluid excessive heat can be destroyed goods in the fluid, and can make this fluid become useless or dangerous in some situation.This temperature drop is violent especially when hanging down flow velocity, and the heat loss that the long holdup time causes in the connection tube behind heater can reach the amount that is before heated.Under high flow velocities, the response time of the heater of prior art heater is an impediment to flow velocity is sharply changed fast reaction and don't makes fluid superheat.
The specific embodiment
The following explanation that provides can make those of ordinary skills understand and apply the invention with the best mode that the inventor understands.But for those of ordinary skills, multiple scheme is arranged obviously, because in this concrete principle of the present invention that limits, provide a kind of venous transfusion fluid heating system, its internal flow is by band heating in of fluid transferred heat.
Fig. 1 illustrates transfusion system sketch map of the present invention.Venous transfusion support 100 supports a flexible container 102, and it stores blood or brine fluids 104 to patient's input.Infusion liquid 104 supplies to present drip chamber 106, and present drip chamber 106 is compiled fluid before transfusion.The pipe 108 that connects present drip chamber 106 is guided flow control valve 110 into, the flow rate of fluid that flow control valve 110 is regulated to patient's supply.Flexible pipe 112 is connected to joint 114 with flow control valve 110, and joint 114 preferably includes a critesistor or other temperature sensor of measuring the fluid original temperature.Joint 114 connects heating control apparatus 116 by electronic installation, and as shown in the figure, heating control apparatus 116 preferably is installed on the venous transfusion support.Heating control apparatus 116, or is powered by dc-battery by AC-powered when needed via its power line 118.
At fluid when joint 114 flows out, the intubate 122 that it flows to patient's transfusion along pipe 120, or other device.As detailed below, conduct heat continuously to fluid along the length of pipe 120.On intubate 122 or near it, be provided with second heat sensor, measurement is direct in the fluid temperature (F.T.) before the patient infuses, and this Temperature Feedback is arrived heating control apparatus 116.By regulating the heat that transmits along pipe 120, can accurately control fluid temperature (F.T.), with suitable temperature input.Like this, the low inducement of body temperature is lowered or elimination.
Fig. 2 illustrates with respect to second embodiment shown in Figure 1, wherein except that gravity, with pressure control flow velocity input infusion liquid 104.With identical numerical code expression same parts, Fig. 2 comprises that a pressure infusion appliance 124 around venous transfusion flexible container 102 is to flexible container 102 pressurizations.The Pressure gauge 126 that is fixed on the pressure infusion appliance 124 is presented at the pressure that adds on the flexible container 102, can be with the artificial transfusion of hand pump 128 pressurization, or with the motor (not shown) mechanical infusion that pressurizes.
Fig. 3 illustrates the cutaway view of pipe 120, and pipe 120 comprises the device of measuring fluid temperature (F.T.) and heating to fluid.Joint 114 is accepted cold fluid from flow speed controller, and the heat sensor in joint 114 130 is measured the temperature of cold fluid.This first heat sensor 130 is measured fluidic overtemperature, and also can be used for determining the fluidic beginning power supply of heating.Flexibility is with 132 to stretch to the joint 114 from managing 120, connects electric lead 134 on joint 114.As shown in Fig. 1, electric lead 134 stretches out from insulated conduit 136 as the front, stretches to heating control apparatus 116.
Pipe 120 measured temperatures that also are included in second heat sensor, 138, the first and second heat sensors of near-end (promptly from the nearest end of patient) feed back to heating control apparatus 116 via conduit 136.In a preferred embodiment, near-end comprises redundant two critesistor, and the alarm of deviation trigger between the two critesistor that form two pick offs has illustrated that a critesistor has departed from predetermined tolerance.Like this, the inefficacy of a critesistor can not cause to the patient and import superheated fluid.Preferably pipe terminates on the road E Shi adapter of being convenient to infuse 140, or on the similar adnexa.
Fig. 3 is shown specifically first electrode 142 and second electrode 143, and they are arranged in flexibility with connecting on 132 end opposite and by being embedded in the conductivity cell 144 of flexibility with 132.First electrode 142 and second electrode 143 are determined at flexibility and are with contingent non-continuous event in 132, as fracture, pin hole, failure of insulation and the bubble that forms on tape.The bubble that forms can cause that excessive power is distributed and focus on tape, and the latter can transfer to damage pipe 120.
Figure 4 and 5 illustrate be arranged in the pipe 120 be with 132.Pipe itself can be the conventional type that venous transfusion is used, as 1/8th inches polyvinyl chloride pipes (PVC).With 132 is flexible, preferably push by a kind of heat proof material with the heating element heater 146 that embeds, as shown in the figure, the diameter of cross-over pipe.Pipe 120 and flexibility are with 132 can be squeezed in together in the integrative-structure, or are with pipe and separate formation, subsequently in the insertion tube.When forming together, be with radially cross-over pipe at band and pipe, integrally form merge point with tube wall on the opposite side of pipe.
Band comprises the heating element heater 146 of heat tape 132, the fluid in the continuous then heating tube 120 of line.In addition, heating element heater 146 also can horizontal or vertical zigzag, strengthens heating on the length of pipe.By electric current, distributing of energy heated heating element heater 146 total lengths along the line in heating element heater 146, then heating tape 132.Through being with 132 o'clock, the heat of band is delivered to fluid by conduction and convection current in the fluid Continuous Flow.With 132 lines 150 that also have a signal that transmits heat sensor 130 and 138, line 150 is preferably along the central part setting of band.Band must be thinned to and can make the pipe can be crooked, is enough to anti-leukorrhagia stopping and splits on length of tube but should be fastened to.The general width of band is about 1/10th inches, but is preferably made by PVC or squeeze polymer.
Fig. 6 illustrates first embodiment of the invention feedback control circuit 152 block diagrams.The signal of near-end critesistor is supplied with amplifier 154, and amplifier 154 increases signal intensity, and amplifying signal shows in display device 156.Temperature signal is guided an error amplifier 158 into, and it receives temperature input best or that wish from heater, and compares these two signals.This difference and a known signal as the triangular wave that produces from triangular-wave generator 162, are supplied with a pulse-width modulator (PWM) comparator 160 together then, and the output of comparator 160 supplies to optoisolator 164.Heater transformator 166 of the output of optoisolator 164 control, it is controlled again with the size of current in the heating heating element heater 146 in 132.When the big heat of needs, be adjusted to power of transformer, increase electric current, improve power to the line confession, produce big heat.The heat that increases passes to fluid, and this has improved the downstream temperature on the near-end critesistor.By this way, remain on optimum temperature on the near-end critesistor.
Fig. 7 illustrates second feedback circuit, and it comprises the dual micro processor heating controller.In this circuit, the signal of two near-end critesistor and a far-end critesistor, through simulate-digital converter 168 converts digital signal to, supplies with first microprocessor 170.Signal 172a, the 172b of three critesistor and 172c and conductivity measured value 176 are parallel to simulate-digital converter 174 by second, and the digital signal 178 of generation is guided second microprocessor 180 with first microprocessor 170 UNICOMs into.A display device 182 is connected first microprocessor with input equipment 184, its processing digital signal and displays temperature in display device 182.The digital signal that the first microprocessor 170 and second microprocessor 180 were handled is supplied with optoisolator 186a and 186b separately respectively, and they are with a main triac and an auxilliary triac test signal.With the power supply of test result adjusting heater transformator 188, regulate the electric current in the line and supply with fluidic heat.
Disclosed heating system is light-duty, QA electric heater, compares with using the fluid heater that adds hot jacket, produces the milder temperature characterisitic change curve for fluid flow.The insider is not departing from the multiple variation scheme that will dream up the foregoing description under the scope and spirit of the present invention.For example, do not departing under the scope and spirit of the present invention, the insider can change feedback control circuit.Similarly, when enforcement is of the present invention, also can carry out other change.Therefore, can understand, within the scope of the claims, the present invention can above-mentioned mode in addition implement.