CN117898305A - Preparation method and application of bifenthrin and chlorantraniliprole termite control composition - Google Patents

Preparation method and application of bifenthrin and chlorantraniliprole termite control composition Download PDF

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CN117898305A
CN117898305A CN202410013274.8A CN202410013274A CN117898305A CN 117898305 A CN117898305 A CN 117898305A CN 202410013274 A CN202410013274 A CN 202410013274A CN 117898305 A CN117898305 A CN 117898305A
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China
Prior art keywords
bifenthrin
chlorantraniliprole
termite control
control composition
termite
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CN202410013274.8A
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Inventor
朱俊连
李贤贤
宋鹏
张春雪
徐明明
朱俊正
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Shandong Huimin Vanda Biological Technology Co ltd
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Shandong Huimin Vanda Biological Technology Co ltd
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Abstract

The application relates to the technical field of termite control preparations, and discloses a preparation method and application of a composition for controlling termites by bifenthrin and chlorantraniliprole. The termite-controlling composition comprises 10-20 parts of bifenthrin and 8-15 parts of chlorantraniliprole. The termite control composition prepared by the application is harmless to the environment and human bodies, and has lasting attracting effect, low mildew rate and excellent trapping and killing effect.

Description

Preparation method and application of bifenthrin and chlorantraniliprole termite control composition
Technical Field
The application relates to the technical field of termite control preparations, in particular to a preparation method and application of a composition for controlling termites by bifenthrin and chlorantraniliprole.
Background
In recent years, the situation that the dam is broken due to termite damage is happened in various places, and the situation that the dam is dangerous due to termite damage is more common.
When the soil dam is bred, the main nest cavity of the mature nest group is generally 60 cm multiplied by 50 cm multiplied by 60 cm (length multiplied by width multiplied by height), the large area digs more than 1 cubic meter of soil in the dam, tens of satellite nest cavities with different sizes or even hundreds of satellite nest cavities are arranged around the main nest cavity, the main nest cavity is communicated with the satellite nest cavity, and the depth of the main nest cavity in the dam is usually about 2 meters or even deeper. Therefore, on one hand, the integrity of the dykes is destroyed, and the resistance of the dykes is reduced; on the other hand, the large termite-tunnel opening excavated by the main nest cavity is large in diameter, the termite tunnel penetrates through the inner slope and the outer slope of the dam, once the water level exceeds the normal water level, the pipe leakage risk is often caused, and the dam dam collapse is caused when rescue is not in time or is improper.
There are two traditional termite control methods: firstly, spray the prevention, it takes time and labor to pollute the environment, secondly dig nest and kill termite, it takes time and labor to kill termite, pollute the environment, and it is difficult to thoroughly radically cure termite. At present, baits are used for killing termites, and although the baits have certain effects, the problems of easy mildew and loss of active ingredients generally exist, and particularly outdoor effects cannot be achieved at all.
Based on the above, it is highly desired to provide a termite control composition which is durable in attracting effect and not liable to mildew.
Disclosure of Invention
In order to solve at least one technical problem, a termite control composition with durable attracting effect and difficult mildew is developed, and the application provides a preparation method and application of the termiticide control composition.
In one aspect, the application provides a composition for controlling termites, which comprises 10-20 parts of bifenthrin and 8-15 parts of chlorantraniliprole.
Optionally, the preparation also comprises the following raw materials in parts by weight: 30-50 parts of cellulose powder, 10-20 parts of charcoal, 5-15 parts of ergosterol, 3-10 parts of fennel ketone, 2-5 parts of propylene glycol and 3-8 parts of mannitol.
By adopting the technical scheme, the bifenthrin and chlorantraniliprole termite control composition prepared by the application is harmless to the environment and human body, and has lasting attracting effect, low mildew rate and excellent attracting and killing effect;
the added biochar has larger specific surface area and rich pore structure, can be used as a carrier of a medicine, improves the stability of the medicine and reduces the loss of active ingredients;
The added ergot alcohol has excellent antibacterial effect, can inhibit the growth and reproduction of pathogenic bacteria, and reduces the possibility of bait mildew; the ergosterol is a termite pheromone, can attract termites to feed before, and has excellent attracting effect; meanwhile, the ergot alcohol is beneficial to promoting the growth and development of plants, enhancing stress resistance, improving the fertility of soil and improving the structure of the soil so as to be beneficial to ecological environment;
the added fennel ketone can inhibit the growth and reproduction of pathogenic bacteria, thereby reducing the possibility of bait mildew; and having a camphora odor as an attractant to attract termites to feed on their way;
The mannitol and the propylene glycol added in the application have excellent attracting effect, antibacterial effect and hygroscopicity; the mannitol has sweet taste and cool mouthfeel, can be used as a phagostimulant in termite baits, can increase attraction to termites, and improves the attraction effect; the mannitol can absorb moisture in the air, reduce the humidity of the surface of the bait, thereby slowing down the growth and propagation of microorganisms in the bait, further reducing the mildew and humidity phenomena of the bait, reducing the mildew rate, simultaneously prolonging the shelf life of the bait and improving the safety of the bait; the added propylene glycol can be used as a solvent to help other components to be better dissolved and mixed, and can play a certain role in corrosion resistance, and has antibacterial property and hygroscopicity.
Optionally, the weight ratio of the ergol to the fennel ketone is 0.8-2:1.
By adopting the technical scheme, the termite control composition prepared by the application has more excellent comprehensive performance.
Optionally, the weight ratio of the propylene glycol to the mannitol is 0.6-1.2:1.
By adopting the technical scheme, the termite control composition prepared from the propylene glycol and the mannitol in the specific proportioning range has excellent hygroscopicity, keeps the dryness of baits, has excellent antibacterial effect and has high-efficiency attracting effect.
Optionally, the weight ratio of the propylene glycol to the mannitol is 0.8:1.
By adopting the technical scheme, the propylene glycol and mannitol with better proportion are selected, and the comprehensive performance is better.
Optionally, the ergot alcohol is esterified ergot alcohol, and the raw materials of the esterified ergot alcohol comprise ergot alcohol, acrylic acid and acetic acid with the weight ratio of 1:0.3-0.8:0.2-0.5.
By adopting the technical scheme, the application uses the esterified ergot alcohol to increase the solubility and stability of the esterified ergot alcohol and improve the attracting effect and the antibacterial effect of the esterified ergot alcohol in the termite control composition; meanwhile, acrylic acid and acetic acid are used as reaction raw materials, the progress of the esterification reaction can be controlled, and the esterified ergot alcohol with purer and high purity can be obtained.
Optionally, the specific surface area of the biochar is 800-2000m 2/g.
By adopting the technical scheme, the biochar with specific surface area in a specific range has higher adsorption performance and reactivity, and can better adsorb and transfer information and substances of other components, thereby enhancing the attraction effect and the poisoning effect of the termite control composition.
Optionally, the biological charcoal further comprises polyglutamic acid, wherein the weight of the polyglutamic acid is 0.4-1.5 times of that of the biological charcoal.
By adopting the technical scheme, the added polyglutamic acid can be used as a carrier of the medicine, so that the stability of the medicine is improved, and the service life of the medicine is prolonged; the termite-resistant water-absorbing agent has strong water absorption and water retention, can promote the permeability and the drug effect of the drug, and enables the drug to enter termites more easily, so that the prevention and control effect of the drug is enhanced; and interfere with termite communication, making termites difficult to find food and breeding sites, thereby playing a role in preventing termites.
In a second aspect, the present application provides a method of preparing a composition for controlling termites comprising the steps of:
S1, mixing and stirring biochar and cellulose powder, and performing ball milling treatment to prepare a mixture A;
s2, mixing and stirring ergot alcohol, fennel ketone, propylene glycol and mannitol to prepare a mixture B;
S3, mixing and stirring the mixture B, bifenthrin and chlorantraniliprole, then adding the mixture A, and continuing to mix and stir to prepare a disinfectant premix;
And S4, pressing and forming the disinfectant premix in a mould to prepare the termite control composition.
By adopting the technical scheme, the preparation method for preparing the termite control composition is simple in operation, convenient and quick, and the raw materials used are natural components, so that the termite control composition is harmless to the environment and human bodies.
Optionally, in S1, the D50 of the mixture a is 80-150nm.
By adopting the technical scheme, the particle size of the specific mixture A is adopted, so that the specific surface area of the particles is larger, and the reactivity is higher, thereby better adsorbing and transmitting information and substances of other components and improving the attracting effect of the termite control composition.
In a third aspect, the present application provides the use of bifenthrin and chlorantraniliprole termite control compositions in the field of termite control.
In summary, the present invention includes at least one of the following beneficial technical effects:
1. The termite control composition prepared by the application is harmless to the environment and human body, and has lasting attracting effect, low mildew rate and excellent attracting and killing effect;
2. The added biochar has larger specific surface area and rich pore structure, can be used as a carrier of a medicine, improves the stability of the medicine and reduces the loss of active ingredients;
3. The added fennel ketone can inhibit the growth and reproduction of pathogenic bacteria, thereby reducing the possibility of bait mildew; and having a camphora odor as an attractant to attract termites to feed on their way;
4. the mannitol and the propylene glycol added in the application have excellent attracting effect, antibacterial effect and hygroscopicity;
5. The preparation method of the termite control composition is simple in operation, convenient and quick, and the raw materials used are natural components, so that the termite control composition is harmless to the environment and human bodies.
Detailed Description
The present application will be described in further detail with reference to examples.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
The raw materials of the application are as follows, and all the raw materials of the application are from commercial sources unless specified otherwise:
Cellulose powder: model 006, available from Shanghai, inc. of new materials science and technology;
biochar: selected from bagasse;
ergot alcohol: CAS number, 602-85-7;
Foeniculum vulgare ketone: CAS number, 7787-20-4;
propylene glycol: CAS number, 57-55-6;
mannitol: CAS number, 87-78-5;
Bifenthrin: branding, source leaves, purity 98%;
chlorantraniliprole: guangzhou Chengbang biotechnology Co., ltd, purity 99%;
Acrylic acid: CAS number, 79-10-7;
acetic acid: CAS number, 64-19-7;
Polyglutamic acid: CAS number 25513-46-6;
The detection item and the detection method are as follows:
Attraction test: taking a certain amount of fine sand, drying in a constant temperature drying oven, scattering the dried fine sand into a plastic basin (diameter is 50 cm), wherein the thickness of the fine sand is about 2mm, spraying a proper amount of distilled water on the fine sand by using a small spray can to keep moist, putting small moist cotton balls as a water source, putting 2g of termite control agents of each embodiment and each comparative example into a plastic cup (diameter is 40mm and height is 30 mm), and arranging an opening at one side of the plastic cup and the width is about 10mm; each example and comparative example were provided with 3 repeating groups of 39 plastic cups in total, randomly arranged and numbered, 1000 workers were placed in the center of the basin and tested in a room temperature and humidity oven (25 ℃,90% rh) in the dark; 7 per day: 00. 19:00 times of observation are carried out for 1 time, water is sprayed on time to keep moisture, and the termite quantity in each plastic cup is observed and recorded; observing for 5d altogether, counting by accumulated termite count in the plastic cup, calculating the relative reaction rate of termite to the termite controlling agent of each example and comparative example according to the following formula, and setting the relative reaction rate of termite controlling agent with the accumulated termite count at most as 100%; the relative response rate reflects the preference degree of termites to the termite-controlling agent, the larger the numerical value is, the stronger the termite-controlling agent is proved to take food,
Relative response% = termite number in treated plastic cup/termite number in plastic cup with maximum occurrence%100%;
mildew conditions: the mildewing of each of the examples and comparative examples was observed simultaneously during the attracting test and continued after the attracting test was completed, and the mildewing of 1 month, 3 months, 6 months, 9 months and 12 months was recorded;
Toxicity test: taking a certain amount of fine sand, drying in a constant temperature drying oven, and scattering the dried fine sand into a plastic basin (with the diameter of 50 cm), wherein the thickness of the fine sand is about 2mm; spraying distilled water on fine sand, placing small wet cotton balls as water source, placing 1000 workers in the center of basin, placing 2g of the termite-controlling agent of each example and comparative example in each colony, observing the death condition of colony after 5d, probability mortality, and testing in dark condition of indoor constant temperature and humidity box (25 deg.C, 90% RH).
Examples 1 to 3
The specific raw material amounts of the termite control compositions of examples 1-3 are shown in Table 1.
TABLE 1
Wherein the specific surface area of the biochar is 800m 2/g.
Example 1
A method of preparing a termite control composition comprising the steps of:
s1, mixing and stirring biochar and cellulose powder, and performing ball milling treatment to prepare a mixture A with D50 of 80 nm;
s2, mixing and stirring ergot alcohol, fennel ketone, propylene glycol and mannitol to prepare a mixture B;
S3, mixing and stirring the mixture B, bifenthrin and chlorantraniliprole, then adding the mixture A, and continuing to mix and stir to prepare a disinfectant premix;
S4, pressing and forming the disinfectant premix in a mould to prepare the termite control composition.
Example 2
A method of preparing a termite control composition comprising the steps of:
s1, mixing and stirring biochar and cellulose powder, and performing ball milling treatment to prepare a mixture A with D50 of 80 nm;
s2, mixing and stirring ergot alcohol, fennel ketone, propylene glycol and mannitol to prepare a mixture B;
S3, mixing and stirring the mixture B, bifenthrin and chlorantraniliprole, then adding the mixture A, and continuing to mix and stir to prepare a disinfectant premix;
S4, pressing and forming the disinfectant premix to prepare the termite control composition.
Example 3
A method of preparing a termite control composition comprising the steps of:
s1, mixing and stirring biochar and cellulose powder, and performing ball milling treatment to prepare a mixture A with D50 of 80 nm;
s2, mixing and stirring ergot alcohol, fennel ketone, propylene glycol and mannitol to prepare a mixture B;
S3, mixing and stirring the mixture B, bifenthrin and chlorantraniliprole, then adding the mixture A, and continuing to mix and stir to prepare a disinfectant premix;
S4, pressing and forming the disinfectant premix to prepare the termite control composition.
Comparative examples 1 to 5
Comparative example 1
The procedure of example 2 was followed except that the biochar was replaced with an equivalent amount of cellulose powder.
Comparative example 2
The procedure is as in example 2, except that equal amounts of fennel ketone are used instead of ergol, except that the ergol is replaced with equivalent amounts of fennel ketone.
Comparative example 3
The procedure is as in example 2, except that equivalent amounts of ergol are used instead of fennel ketone, except that the components and preparation are the same as in example 2.
Comparative example 4
The procedure is as in example 2, except that the propylene glycol is replaced by equal amounts of mannitol.
Comparative example 5
The procedure is as in example 2, except that the mannitol is replaced by equal amounts of propylene glycol.
The termite control compositions prepared in examples 1 to 3 and comparative examples 1 to 5 were subjected to index detection, and the detection results are shown in Table 2.
TABLE 2
From examples 1 to 3, comparative examples 1 to 5 and Table 2, the termite control composition prepared by the present application is not only harmless to the environment and the human body, but also durable in attracting effect, low in mildew rate and excellent in attracting and killing effect;
as is clear from comparative example 1, example 2 and table 2, the termite control composition prepared by the present application has poor trapping and killing effects and is easy to mold, and the inventor speculates that the biochar has a large specific surface area and a rich pore structure, can adsorb moisture and organic substances, reduces the risk of wetting and molding of the biological agent, and simultaneously, the biochar can also form a protective film to prevent the invasion of moisture and microorganisms; and has a certain antimicrobial effect, and can inhibit the growth and propagation of microorganisms, thereby reducing the mildew risk;
As can be seen from comparative examples 2 to 3, example 2 and table 2, the ergot alcohol and fennel ketone compound system adopted in the application has excellent antibacterial effect, the prepared termite control composition is not easy to mildew, and the ergot alcohol prepared termite control composition has excellent attracting effect;
As is clear from comparative examples 4 to 5, example 2 and Table 2, the present application uses propylene glycol and mannitol which have excellent hygroscopicity, mannitol has a cool taste, a more attractive effect than propylene glycol, and propylene glycol has a more antiseptic effect.
Examples 4 to 5
The ingredients and preparation were the same as in example 2 except that the weight ratio of ergol to fennel ketone was different based on example 2, wherein the total weight of ergol and fennel ketone was 25g.
Example 4
The weight ratio of ergol to fennel ketone is 0.8:1.
Example 5
The weight ratio of ergol to fennel ketone is 2:1.
Examples 6 to 8
The components and preparation were the same as in example 2 except that the weight ratio of propylene glycol and mannitol was different based on example 2, wherein the total weight of propylene glycol and mannitol was 10g.
Example 6
The weight ratio of propylene glycol to mannitol was 0.6:1.
Example 7
The weight ratio of propylene glycol to mannitol was 0.8:1.
Example 8
The weight ratio of propylene glycol to mannitol was 1.2:1.
Examples 9 to 10
The procedure of example 7 was followed except that the specific surface area of the biochar was varied, and the other components and preparation methods were the same as those of example 7.
Example 9
The specific surface area of the biochar is 1500m 2/g.
Example 10
The specific surface area of the biochar is 2000m 2/g.
The termite control compositions prepared in examples 4 to 10 were subjected to performance test, and the test results are shown in Table 3.
TABLE 3 Table 3
From examples 4-5, 2 and Table 3, the composition for controlling termites prepared by adopting the ergosterol and the fennel ketone with better proportion has better comprehensive performance;
from examples 6-8, 2 and Table 3, the termite control composition prepared by adopting the propylene glycol and the mannitol with better proportion has better attracting effect;
as can be seen from examples 9-10, 2 and Table 3, the application selects the better biochar specific surface area, can improve the stability of raw materials, reduce the loss of active ingredients, improve the comprehensive performance of the termite control composition, and can last for 9 months without mildew after detection.
Examples 11 to 13
Based on example 9, the components and preparation method were the same as in example 9 except that equivalent amounts of esterified ergot alcohol were used instead of ergot alcohol, wherein starting materials for the esterified ergot alcohol include ergot alcohol, acrylic acid and acetic acid;
The preparation method of the esterified ergot alcohol comprises the following steps: mixing ergot alcohol, acrylic acid and acetic acid together according to a proportion to obtain a mixed solution; heating the mixed solution to 120 ℃, reacting for 2 hours under the condition of stirring, and cooling to room temperature; and filtering and purifying to obtain esterified ergol.
Example 11
The weight ratio of ergol, acrylic acid and acetic acid is 1:0.3:0.2.
Example 12
The weight ratio of ergol, acrylic acid and acetic acid is 1:0.5:0.3.
Example 13
The weight ratio of ergol, acrylic acid and acetic acid is 1:0.8:0.5.
Examples 14 to 16
Based on example 12, the other components were the same as in example 12 except that polyglutamic acid was further added;
The preparation method of the termite control composition comprises the following steps: firstly, mixing and stirring biochar and cellulose powder, and then performing ball milling treatment to prepare a mixture A with D50 of 80 nm;
step two, mixing and stirring the mixture A and polyglutamic acid to prepare a mixture C;
Step three, mixing and stirring ergot alcohol, fennel ketone, propylene glycol and mannitol to prepare a mixture B;
Step four, mixing and stirring the mixture B, bifenthrin and chlorantraniliprole, then adding the mixture C, and continuing to mix and stir to prepare a disinfectant premix;
And fifthly, pressing and forming the disinfectant premix to prepare the termite control composition.
Example 14
The weight of polyglutamic acid is 0.4 times of the weight of the biochar.
Example 15
The weight of polyglutamic acid is 0.9 times of the weight of the biochar.
Example 16
The weight of polyglutamic acid is 1.5 times of that of the biochar.
Examples 17 to 18
The procedure of example 15 was followed except that the particle size of mixture A in S1 was varied, and the composition and preparation were the same as in example 15.
Example 17
The D50 of the mixture A in S1 is 100nm.
Example 18
The D50 of mixture A in S1 is 150nm.
The termite control compositions prepared in examples 11 to 18 were subjected to performance test, and the test results are shown in Table 4.
TABLE 4 Table 4
As can be seen from examples 11 to 13, 9 and table 4, the use of esterified ergot alcohol according to the present application can increase its solubility and stability, which is superior to the use of ergot alcohol for the preparation of termite control compositions;
As can be seen from examples 14-16, 12 and Table 4, the application also adds polyglutamic acid, which can be used as a carrier of the medicine as biochar, so as to improve the stability of the medicine and prolong the service life of the medicine; and has strong water absorbability and water retention property, and can promote the penetrability and efficacy of the drug, so that the drug can enter termites more easily, thereby enhancing the control effect of the drug.
As is clear from examples 17 to 18, 15 and Table 4, the particle size of the specific mixture A is adopted in the application, so that the particles are finer, the specific surface area is larger, and the reactivity is higher, thereby better adsorbing and transmitting information and substances of other components and improving the attracting effect of the termite control composition.
The above embodiments are not intended to limit the scope of the present application, so: all equivalent changes according to the principles of the present application should be covered by the scope of the present application.

Claims (10)

1. The composition for controlling termite is characterized by comprising 10-20 parts of bifenthrin and 8-15 parts of chlorantraniliprole.
2. The bifenthrin and chlorantraniliprole termite control composition according to claim 1, further comprising the following raw materials in parts by weight: 30-50 parts of cellulose powder, 10-20 parts of charcoal, 5-15 parts of ergosterol, 3-10 parts of fennel ketone, 2-5 parts of propylene glycol and 3-8 parts of mannitol.
3. The bifenthrin and chlorantraniliprole termite control composition according to claim 2, wherein the weight ratio of ergol to fennel ketone is 0.8-2:1.
4. The bifenthrin and chlorantraniliprole termite control composition according to claim 2, wherein the weight ratio of propylene glycol to mannitol is 0.6-1.2:1.
5. The bifenthrin and chlorantraniliprole termite control composition according to claim 2, wherein the ergol is esterified ergol, and the raw materials of the esterified ergol comprise ergol, acrylic acid and acetic acid in a weight ratio of 1:0.3-0.8:0.2-0.5.
6. The bifenthrin and chlorantraniliprole termite control composition according to claim 2, wherein the biochar has a specific surface area of 800-2000m 2/g.
7. The bifenthrin and chlorantraniliprole termite control composition according to claim 2, further comprising polyglutamic acid, wherein the polyglutamic acid is 0.4-1.5 times the weight of the biochar.
8. A method of preparing the bifenthrin and chlorantraniliprole termite control composition of claim 2, comprising the steps of:
S1, mixing and stirring biochar and cellulose powder, and performing ball milling treatment to prepare a mixture A;
s2, mixing and stirring ergot alcohol, fennel ketone, propylene glycol and mannitol to prepare a mixture B;
S3, mixing and stirring the mixture B, bifenthrin and chlorantraniliprole, then adding the mixture A, and continuing to mix and stir to prepare a disinfectant premix;
S4, pressing and forming the disinfectant premix in a mould to prepare the bifenthrin and chlorantraniliprole termite control composition.
9. The method for preparing a composition for controlling termites, comprising bifenthrin and chlorantraniliprole according to claim 8, wherein in S1, the D50 of the mixture a is 80-150nm.
10. Use of the bifenthrin and chlorantraniliprole termite control composition of claim 1 in the field of termite control.
CN202410013274.8A 2024-01-04 2024-01-04 Preparation method and application of bifenthrin and chlorantraniliprole termite control composition Pending CN117898305A (en)

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