CN117730164A - Method for managing cell quality and method for producing cell - Google Patents

Method for managing cell quality and method for producing cell Download PDF

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Publication number
CN117730164A
CN117730164A CN202280049814.7A CN202280049814A CN117730164A CN 117730164 A CN117730164 A CN 117730164A CN 202280049814 A CN202280049814 A CN 202280049814A CN 117730164 A CN117730164 A CN 117730164A
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protein
cells
cell
receptor
factor
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中村健太郎
北桥宗
芳野雄一
古川谅
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Fujifilm Corp
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Fujifilm Corp
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Priority claimed from PCT/JP2022/005294 external-priority patent/WO2023286305A1/en
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Abstract

The present invention addresses the problem of providing a method for managing the quality of cells, which can screen cells having a drug effect, and a method for producing cells using the method for managing the quality. According to the present invention, there is provided a method for quality management of cells for therapeutic or pharmaceutical development, the method comprising: a step of managing the behavior of one or more specific protein molecules necessary for the development of a cell-based therapeutic effect and a step of managing the expression behavior of the relevant genome characteristic of the above-mentioned cells.

Description

Method for managing cell quality and method for producing cell
Technical Field
The present invention relates to a method for quality management of cells for therapeutic or pharmaceutical development, the method comprising: a step of managing the behavior of specific protein molecules necessary for the manifestation of the therapeutic effect and a step of managing the expression behavior of related genomes characteristic of cells. The invention also relates to a method for manufacturing cells by using the quality control method.
Background
In recent years, with the progress of regenerative medicine technology and cell therapy technology, development of various cell therapy or research cell products using autologous, allogenic or xenogenic cells has been actively conducted. For example, mesenchymal stem cells (mesenchymal stem cell: MSC) are promising as a source of cells for useful cell therapy. Regarding mesenchymal stem cells, the following are reported: can be collected from various body tissues and can be isolated from bone marrow tissue (non-patent document 1), adipose tissue (non-patent document 2), muscle tissue (non-patent document 3), synovial tissue (non-patent document 4), periosteal tissue (non-patent document 5) or the like. In particular, regarding mesenchymal stem cells derived from synovium, the following is reported: the mesenchymal stem cells derived from various mesenchymal tissues such as bone marrow have higher proliferation and cartilage formation abilities (non-patent document 6).
Patent documents 1 and 2 disclose methods for treating articular cartilage damage or meniscus damage using mesenchymal stem cells derived from synovium.
On the other hand, it is known that in quality control of cell products, it is extremely difficult to ensure the equivalence and identity of each batch. This is mainly because the cells constituting the product are not themselves completely homogeneous structures, and thus it is difficult to determine the characteristics thereof. Therefore, in order to manage the quality of the product, not only the quality test of the final product but also QMS concepts applied to medical equipment are introduced, and the manufacturing raw materials, material management, manufacturing process management, and process management test are recorded and controlled, thereby performing the management of the entire process. However, as science and technology advances, it becomes increasingly important to identify and characterize the cells themselves as the final product. As a method for quality control of cells, for example, a method using expression of several specific proteins as an index (patent document 3) has been reported, but it has not been satisfactory so far.
Prior art literature
Non-patent literature
Non-patent document 1: prockop, D.J.,1997, science.276:71-4
Non-patent document 2: zuk, P.A. et al 2002,Mol Biol Cell.13:4279-95
Non-patent document 3: cao et al 2003,Nat Cell Biol.5:640-6
Non-patent document 4: de Bari, C.et al 2001,Arthritis Rheum.44:1928-42
Non-patent document 5: fukumoto, T et al, 2003, osteoarothoristis Cartillage.11:55-64
Non-patent document 6: sakaguchi et al 2005,Arthritis Rheum.52:2521-9
Patent literature
Patent document 1: japanese patent No. 5928961
Patent document 2: japanese patent No. 5656183
Patent document 3: japanese patent laid-open No. 2018-117582
Disclosure of Invention
Technical problem to be solved by the invention
Conventionally, as described in patent document 3, a method of managing the expression levels of several specific proteins has been disclosed in quality control of cell products. However, the above-mentioned methods are insufficient as methods for identifying crude substances such as control cells, and as a result, it is clear that the problems such as the equivalence and homogeneity of cell products cannot be completely controlled. Furthermore, in cell therapy products, it is also required to identify molecules involved in direct drug effects and to perform management and control.
The present invention provides a method for quality control of cells, which can screen cells having a drug effect, and a method for producing cells using the quality control method.
Means for solving the technical problems
As a result of diligent studies to solve the above problems, the present inventors have found that, according to the present invention, cells having a positive drug effect can be successfully selected by a mechanism of action molecule while a similar cell population is separately managed by combining the management of a specific protein molecule necessary for the drug effect related to the mechanism of action and the management of a related genomic expression behavior pattern characteristic of the cell population. The present invention has been completed based on the above findings.
That is, according to the present invention, the following invention is provided.
1 > a method for quality management of cells for therapeutic or drug development, the method comprising:
a step of managing the behavior of one or more specific protein molecules necessary for the development of a cell-based therapeutic effect and a step of managing the expression behavior of the relevant genome characteristic of the above-mentioned cells.
< 2 > the method according to < 1 >, wherein,
the relevant genome characteristic of the above-mentioned cells is composed of 10 to 2000 genes.
The method according to < 3 > is < 1 > or < 2 >, wherein,
the related genome characteristic of the above cell is selected from at least 1 or more of immune-related genome, inflammation-related genome, angiogenesis-related genome, nerve regeneration-related genome, cartilage formation-related genome, bone formation-related genome, adipogenesis-related genome, fibrosis-related genome, immunogenicity-related genome, migration-related genome, adhesion-related genome, aging-related genome, mesenchymal stem cell marker-related genome, surface marker-related genome, growth factor-related genome, chemokine or cytokine-related genome.
The method according to any one of < 1 > to < 3 >, wherein,
when the expression behavior of the cell-characteristic related genome is managed, it is determined that the cell is usable when the correlation between the expression pattern of the genome obtained by measuring the expression state of the cell-characteristic related genome and the expression pattern as a reference is a certain level or more.
< 5 > the method according to < 4 >, wherein,
the case where the correlation is a certain degree or more is a case where the correlation coefficient or the determination coefficient, or the correlation coefficient and the determination coefficient are evaluated and the correlation coefficient or the determination coefficient is a certain degree or more.
< 6 > the method according to < 5 >, wherein,
in the case of evaluating the correlation coefficient or the determination coefficient, the method is carried out by
(i) The measurement lower limit value is used to replace the defect value of the expression quantity of the non-measurable gene,
(ii) Replacing defective value of the expression level of the gene which cannot be measured with the lowest value among the measured values, or
(iii) The following formula is used: the read count + (1X gene length/average gene length) of each gene was used to treat a defective value where the expression level of the gene could not be measured,
either one of the correlation coefficient or the determination coefficient is calculated.
The method according to any one of < 1 > to < 6 >, wherein,
the specific protein molecule is a cell surface antigen.
The method according to any one of < 1 > to < 7 > wherein,
the specific protein molecule includes one or more of CD29 and CD140 b.
The method according to any one of < 1 > to < 8 >, wherein,
the behavior of the specific protein molecule is the expression level.
The method according to any one of < 1 > to < 9 > wherein,
the cells are at least one cell selected from the group consisting of adult stem cells, induced pluripotent stem cells, embryonic stem cells, differentiated cells derived from adult stem cells, differentiated cells derived from induced pluripotent stem cells, and differentiated cells derived from embryonic stem cells.
The method according to any one of < 1 > to < 10 >, wherein,
the cells are mesenchymal stem cells.
The method according to any one of < 1 > to < 11 >, wherein,
the above-mentioned cells are cells used as therapeutic drugs for arthrosis.
The method according to any one of < 1 > to < 12 >, wherein,
the above-mentioned cells are cells useful as a therapeutic agent for meniscus or a therapeutic agent for osteoarthritis.
The method according to any one of < 1 > to < 11 >, wherein,
the above cells are cells used for drug development.
< 15 > a method of making a cell for therapeutic or drug development comprising:
a step of obtaining a candidate cell population comprising cells for therapeutic or drug development; and
A step of selecting cells satisfying the criterion from the above cell population by the method of any one of < 1 > to < 14 >.
Effects of the invention
According to the present invention, the therapeutic effect can be ensured by identifying molecules necessary for managing the expression of the drug effect that is most important for the therapeutic cells. Further, according to the present invention, it is possible to clearly express the quality control of the equivalence and homogeneity of cells which cannot be completely ensured by drug-effect expression alone by distinguishing them from similar cells.
Drawings
Fig. 1 shows images of the medial meniscus of the knee in a meniscus injury model and control.
Fig. 2 shows the results of evaluating the efficacy of synovial stem cells that block specific proteins in a model of meniscus injury.
FIG. 3 shows the results of evaluating the efficacy of synovial stem cells deleted for specific proteins by gene knockout in a model of meniscus injury.
Detailed Description
The following describes the present invention in detail. In the present specification, "to" is used in a meaning including numerical values before and after the description as a lower limit value and an upper limit value.
The quality management method of cells for therapeutic or drug development based on the present invention comprises: a step of managing the behavior of one or more specific protein molecules necessary for the development of a cell-based therapeutic effect and a step of managing the expression behavior of the relevant genome characteristic of the above-mentioned cells.
The step of managing the behavior of one or more specific protein molecules necessary for the development of a therapeutic effect based on cells is quality control (first quality control) based on identification management of mechanism-of-action molecules necessary for the direct drug effect possessed by cells.
The step of managing the expression behavior of the relevant genome characteristic of the cells is to find a specific gene expression pattern in a cell population containing a non-mechanism molecule which is not necessarily essential for the efficacy of the cells directly, and determine the quality control (second quality control) of the cells from the crude population by the pattern.
The invention is characterized by combining the two quality management. By the first quality control, a cell exhibiting a reliable drug effect can be produced, and the equivalence and homogeneity of the effectiveness of the drug effect can be controlled. By the second quality control, the equivalence and homogeneity of the cell population can be controlled. In the present invention, by the above two quality management, quality management of cells ensuring effectiveness, safety, equivalence and homogeneity can be performed, and thus a cell therapy product can be provided.
< cell >
The cells are not particularly limited, but preferably at least one cell selected from the group consisting of adult stem cells, induced pluripotent stem cells (iPS cells), embryonic stem cells (ES cells), differentiated cells derived from adult stem cells, differentiated cells derived from induced pluripotent stem cells, and differentiated cells derived from embryonic stem cells can be used.
As the adult stem cells, adult stem cells existing in bone marrow, blood, skin (epidermis, dermis, subcutaneous tissue), fat, hair follicle, brain, nerve, liver, pancreas, kidney, muscle, or other tissues can be used. As the adult stem cells, preferably, mesenchymal stem cells can be used.
Mesenchymal stem cells are known to exist in bone marrow, synovium, periosteum, adipose tissue, muscle tissue, etc., and are known to have the ability to differentiate into osteoblasts, chondrocytes, adipocytes, and tendon cells. Among the above mesenchymal stem cells, synovial-derived mesenchymal stem cells are known to have high chondrogenic capacity.
An induced pluripotent stem cell (iPS cell) is a cell having Pluripotency (multipotency) and proliferation ability, which is produced by reprogramming somatic cells by introducing an initialization factor or the like. The somatic cells used for producing iPS cells are not particularly limited, and may be differentiated somatic cells or undifferentiated stem cells.
The basic method for producing iPS cells is a method in which 4 factors, that is, oct3/4, sox2, klf4, and c-Myc, are introduced into cells by using viruses. There are reports on human iPS cells established by introducing 4 factors, oct4, sox2, lin28, and Nanog. It has also been reported that iPS cells are established by introducing 3 factors other than c-Myc, 2 factors of Oct3/4 and Klf4, or only Oct 3/4. Also, a method of introducing a protein, which is an expression product of a gene, into a cell has been reported. Regarding the gene transfer method, a technique using retrovirus, lentivirus, adenovirus, plastid, transposon vector or transposon vector has also been developed.
The embryonic stem cells (ES cells) can be established by, for example, culturing early embryo before implantation, internal cell mass constituting the early embryo, individual blastocysts, and the like. As the early embryo, an early embryo produced by nuclear transfer of the nucleus of somatic cells can be used. As early embryo, parthenogenesis embryo may be used. Some ES cells may be obtained from a preservation facility or marketed. For example, human ES cells are available from the national institute of health and medical research (National Center for Child Health and Development) (e.g., SEES 1-7), the University of Kyoto institute of regenerative medicine (Institute for Frontier Medical Sciences, kyoto University) (e.g., khES-1, khES-2 and KhES-3), wiCellResearch Institute, ESI BIO, etc.
The source of the cells is not particularly limited, and for example, cells of mammals such as humans, monkeys, mice, rats, guinea pigs, rabbits, cats, dogs, horses, cows, sheep, goats, and pigs can be used.
In the case of using the cells managed by the method of the present invention for therapy, the cells may be autologous cells or allogeneic cells, but are preferably autologous cells.
In the present invention, differentiated cells derived from adult stem cells, differentiated cells derived from induced pluripotent stem cells, or differentiated cells derived from embryonic stem cells may be used.
Conditions and operations of culture methods for differentiation induction to obtain differentiated cells are well known in the art.
As the medium for differentiation induction of stem cells, basal media such as Dulbecco's Modified Eagle Medium (dulbeck's modified eagle medium) (D-MEM), minimum Essential Medium (minimum essential medium) (MEM), RPMI1640, basal Medium Eagle (eagle Basal Medium) (BME), dulbecco's Modified Eagle Medium, to basal media containing components (inorganic salts, carbohydrates, hormones, essential amino acids, nonessential amino acids, vitamins, fatty acids) necessary for survival and proliferation of stem cells can be used: nutrient Mixture F-12 (Dulbecco's modified eagle's medium: nutrient mixture F-12) (D-MEM/F-12), glasgow Minimum Essential Medium (Grasgow minimum essential medium) (Glasgow MEM), hank's liquid (Hank's balanced salt solution) to which at least 1 differentiation inducing factor corresponding to a cell targeted for differentiation induction was added. Examples of the adipocyte differentiation-inducing factor include Dexamethasone (DEX), 3-isobutyl-1-methylxanthine (IBMX), indomethacin (IDM), insulin (Ins), troglitazone, and biotin. Examples of the osteoblast differentiation-inducing factors include Dexamethasone (DEX), hydrocortisone, β -glycerophosphate, ascorbic acid, BMP4, BMP2, and the like. Examples of the chondrocyte differentiation-inducing factor include TGF-. Beta.3, dexamethasone (DEX), and ascorbic acid diphosphate. In order to increase the proliferation rate of cells, if necessary, a growth factor such as basic fibroblast growth factor (bFGF) or epithelial cell growth factor (EGF), tumor Necrosis Factor (TNF), vitamins, interleukins, insulin, transferrin, heparin, heparan sulfate (Heparan sulfate), collagen, bovine Serum Albumin (BSA), fibronectin (Fibronectin), luteinizing hormone (progestrone), selenite, B27-supplement, N2-supplement, ITS-supplement, and the like may be added to the above-mentioned medium, and an antibiotic (penicillin, streptomycin, and the like) may be added. The components of the medium are sterilized by a suitable method. In addition to the above, it is preferable that the serum (for example, 10% Fetal Bovine Serum (FBS)) is contained at a content of 1 to 20%.
The differentiation-inducing medium to which the differentiation-inducing factor of the target cell is added is commercially available, and these commercially available mediums can be used.
For proliferation and differentiation of stem cellsThe culture temperature for induction varies depending on the source of the cells, but is preferably 30℃to 40℃and more preferably 36℃to 38℃in the case of a human origin, for example. And, regarding CO 2 The gas concentration is, for example, preferably about 1 to 10%, more preferably about 2 to 5%.
The confirmation of the differentiation induction into the target cell can be performed by a known method according to the type of differentiated cell. For example, confirmation of differentiation induction into adipocytes can be performed by a method of staining cells with oil red O, a method of measuring the amount of triglyceride in cells, a method of measuring the expression amount of peroxisome proliferator-activated receptor- γ (pparγ) gene in cells, and the like. The confirmation of the induction of differentiation into osteoblasts can be performed by a method of quantifying the amount of calcium deposition of cells, a method of staining cells with alkaline phosphatase, a method of measuring alkaline phosphatase activity of cells, a method of measuring the expression amount of ostreex (osteix) in cells, or the like. The confirmation of the induction of differentiation into chondrocytes can be performed by a method of quantifying the amount of glycosaminopolysaccharide in the cells, a method of staining the cells with Alcian blue (Alcian blue), a method of measuring the expression amount of collagen type II (Collagen type II) in the cells, or the like.
Step of managing the behavior of one or more specific protein molecules necessary for the manifestation of a cell-based therapeutic effect
In the first quality management, the behavior of one or more specific protein molecules necessary for the development of a cell-based therapeutic effect is managed.
The specific protein molecule is not particularly limited, but is preferably a cell surface antigen, and more preferably contains one or more of CD29 and CD140 b.
The step of managing the behavior of the specific protein molecule may specifically be a step of managing the expression level of the specific protein molecule.
The expression level of a specific protein molecule refers to the expression level of a gene of a specific protein or the expression level of a specific protein. The expression level of a specific protein molecule can be calculated as an absolute value or a relative value (ratio or difference between the expression level and a comparative control or reference expression level, etc.).
The expression level of a specific protein molecule can be determined by any method known to the skilled person and can be carried out according to a conventional method. As a measurement of the expression level of a specific protein molecule, the amount of mRNA which is a transcription product of a gene can be measured. The method for measuring the amount of mRNA is not particularly limited as long as it is a method capable of measuring a desired amount of mRNA, and can be appropriately selected from known methods. For example, a gene amplification method using an oligonucleotide hybridizing to a gene encoding a specific protein molecule as a primer or a hybridization method using an oligo (poly) nucleotide hybridizing to a gene encoding a specific protein molecule as a probe can be used. Specifically, the method may include RT-PCR (reverse transcription polymerase chain reaction), real-time RT-PCR, DNA microarray, cell array, northern blotting, spotting, and ribonuclease protection assay.
The primer or probe used in the above measurement method can be labeled, and the amount of mRNA can be measured by detecting the signal intensity of the label. The real-time RT-PCR method is preferable in view of being able to use RNA directly in a sample and to be able to determine a gene by optically measuring a gene amplification process and quantifying the gene according to the number of temperature cycles necessary for amplification. In addition, as a control, the expression level of a gene encoding a specific protein molecule can be normalized using the expression level of mRNA such as glyceraldehyde-3-phosphate dehydrogenase (GAPDH) or β -actin, which are housekeeping genes. In addition, the primers and probes used in the above-described measurement method can be appropriately designed and prepared by the skilled person based on information on the base sequence of the gene encoding the specific protein molecule.
As the measurement of the expression level of the protein, for example, a method of performing an immunological measurement using an antibody or an antibody fragment against a specific protein can be used. Specifically, flow cytometry, immunoblotting, enzyme immunoassay (ELISA), radioimmunoassay (RIA), fluorescent antibody method, cell array method, and the like can be mentioned. These measurement methods can also be implemented by a protocol of a conventional method or a protocol obtained by appropriately modifying and changing a protocol of a conventional method.
For example, when the expression level of a protein in a cell is measured by flow cytometry, it can be evaluated that the cell quality is high when the positive rate of a specific protein is preferably 70% or more, more preferably 80% or more, and still more preferably 90% or more.
In the present invention, the first quality control can be performed by, for example, comparing the expression level of a specific protein molecule in a cell measured by the above method with a predetermined reference expression level. The reference expression level may be, for example, the expression level of a specific protein molecule of a cell (positive control) having been confirmed to have a certain quality, or the expression level of a cell (negative control) having not been confirmed to have a certain quality.
By comparing the expression level of the specific protein molecule of the cell with the reference expression level, it can be evaluated that the cell quality is high when the expression level of the specific protein molecule of the cell is equal to or higher than the expression level of the positive control, and that the cell quality is low when the expression level of the specific protein molecule of the cell is equal to or lower than the expression level of the negative control.
The cutoff value of the expression level of the specific protein molecule may be set in advance, and the expression level of the specific protein molecule measured for the cell may be compared with the cutoff value. The cutoff value can be set to the expression level of the specific protein molecule providing the desired therapeutic effect, for example, based on a regression line indicating the correlation between the expression level of the specific protein molecule and the therapeutic effect. For example, when the expression level of a specific protein molecule in a cell is equal to or higher than a cutoff value, it can be evaluated that the quality of the cell is high, and when the expression level is equal to or lower than the cutoff value, it can be evaluated that the quality of the cell is low.
Step of managing expression behavior of related genome characteristic of cell
In the second quality management, the expression behavior of the relevant genome characteristic of the cell is managed.
The relevant genome characteristic of the cell is preferably composed of 10 to 5000 genes. More preferably, it is composed of 10 to 2000 genes. The lower limit of the number of genes may be 20 or more, 30 or more, 40 or more, 50 or more, 100 or more, 200 or more, 300 or more, or 500 or more. The upper limit of the number of genes may be 4000 or less, 3000 or less, 2000 or less, 1500 or less.
The genome related to the characteristics of the cell is not particularly limited, and can be appropriately selected according to the type of the cell. As an example, when the cells are mesenchymal stem cells, at least 1 or more (for example, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15 or 16 of the above-mentioned genomes) of immune-related genome, inflammatory-related genome, angiogenesis-related genome, nerve regeneration-related genome, cartilage formation-related genome, bone formation-related genome, adipogenesis-related genome, fibrosis-related genome, immunogenicity-related genome, migration-related genome, adhesion-related genome, aging-related genome, mesenchymal stem cell marker-related genome, surface marker-related genome, growth factor-related genome, and chemokine-or cytokine-related genome can be selected.
For example, the above-mentioned various genomes can be collected using commercially available genetic packages, literature information, data of microarrays, a well-known database (e.g., an ontology database (Ontology database) (http:// www.informatics.jax.org/vocab/gene_ontology /), and the like). Furthermore, a gene having a high frequency of occurrence can be selected from the collected genome and used.
In the second quality control, it can be determined that the cell is usable by measuring the correlation between the expression pattern of the genome obtained by measuring the expression state of the relevant genome characteristic of the cell and the expression pattern as a reference. Specifically, when the correlation between the expression pattern of the genome obtained by measuring the expression state of the related genome characteristic of the cell and the expression pattern serving as a reference is a certain level or more, it can be determined that the cell is usable. For example, when a correlation coefficient or a determination coefficient between an expression pattern of a genome obtained by measuring the expression state of a related genome characteristic of a cell and a reference expression pattern, or a correlation coefficient and a determination coefficient are evaluated, and the correlation coefficient or the determination coefficient is at least a certain level, it can be determined that the cell is usable.
The method for measuring the expression state is not particularly limited, but the amount of mRNA can be measured. The method for measuring the amount of mRNA is not particularly limited as long as it is a method capable of measuring a desired amount of mRNA, and can be appropriately selected from known methods. For example, RNA Sequencing (RNA-Seq), RT-PCR, or real-time RT-PCR can be used.
As a method for calculating the determination coefficient, various methods can be adopted, and are not particularly limited. As an example, a method using the RSQ function adopted in Microsoft Excel (registered trademark) can be used. The RSQ function is used to set a decision coefficient between two target samples by returning a value (decision coefficient) obtained by multiplying r by 2 times, using a regression line of the (x, y) pair of the total genome, which is composed of the expression level y of a certain gene in the first target sample and the expression level x of the same gene in the second target sample.
As a method for calculating the correlation coefficient, various methods can be employed, and are not particularly limited. As an example, a method using the CORREL function adopted in Microsoft Excel (registered trademark) can be used. By using the CORREL function, the correlation coefficient between two target samples can be set by returning the value of the correlation coefficient of the (x, y) pair of the total genome, which is composed of the expression level y of a certain gene in the first target sample and the expression level x of the same gene in the second target sample.
In the case of evaluating the correlation coefficient or determining the coefficient, by performing
(i) The measurement lower limit value is used to replace the defect value of the expression quantity of the non-measurable gene,
(ii) Replacing defective value of the expression level of the gene which cannot be measured with the lowest value among the measured values, or
(iii) The following formula is used: the read count of each gene + (1X average of gene length/gene length) was obtained by treating a defective value where the expression level of the gene could not be measured,
Either one of the correlation coefficient or the determination coefficient is calculated.
The RNA Sequencing method (RNA-Seq) is one of methods for quantifying the amount of gene expression using a sequencer. As an analysis flow, (1) quality control is performed on the leads output from the sequencer, (2) the leads are mapped onto the reference sequence, and then (3) statistics are made as to which gene region several leads are mapped. The number of leads counted for each gene region can be regarded as the relative expression level of the gene. That is, the read count of each gene is an output result generally obtained in gene expression analysis, and is a value counted for each gene region.
The threshold value of the determination coefficient or the correlation coefficient may be selected from, for example, 0.70 or more, 0.71 or more, 0.72 or more, 0.73 or more, 0.74 or more, 0.75 or more, 0.76 or more, 0.77 or more, 0.78 or more, 0.79 or more, 0.80 or more, 0.81 or more, 0.82 or more, 0.83 or more, 0.84 or more, 0.85 or more, 0.86 or more, 0.87 or more, 0.88 or more, 0.89 or more, and the like depending on the cell type to be differentiated.
Method for producing cells for therapeutic or pharmaceutical development and use of cells
According to the present invention, after obtaining a candidate cell population including cells for therapeutic or drug development, cells satisfying a criterion are selected from the cell population by the quality control method based on the cells of the present invention, so that cells for therapeutic or drug development can be produced.
Cells of which the quality has been confirmed by the present invention can be used in regenerative medicine or basic research (for example, drug development, etc.). For example, the cells of which the quality has been confirmed by the present invention can be used as a graft material for the purpose of treatment or cosmesis of damage or disorder of living tissue. In one example of the present invention, the cells are cells used as therapeutic agents for arthrosis. For example, the cells may be cells used as a meniscus therapeutic agent or an osteoarthritis therapeutic agent.
As an example, the following describes the case where mesenchymal stem cells derived from synovium are used as an arthropathy therapeutic agent (osteoarthritis therapeutic agent or the like) or a meniscus therapeutic agent.
Synovial tissue can be harvested from joints under anesthesia. The excised synovial tissue is subjected to enzymatic treatment with a protease such as collagenase or trypsin, and the enzymatic treated cells are passed through a mesh filter for filtration. The nucleated cells recovered by the above method can be selected by quality control in the method of the present invention, and the selected cells can be used in therapy.
Mesenchymal stem cells derived from synovium can be cultured and proliferated in ex vivo without the need of differentiating induction thereof in advance by a differentiation medium. The undifferentiated synovial-derived mesenchymal stem cells proliferated in the above manner can be transplanted into a patient. In order to achieve effective treatment, only every 10cm 2 The implantation of cartilage defect or meniscus defect of about size is preferably 5×10 7 More preferably 1X 10 8 More than one mesenchymal stem cells may be used.
In another example of the invention, the cells can be used in drug development. As an example, the cells whose quality has been controlled by the method of the present invention can be used to evaluate the efficacy or toxicity of a drug candidate and to screen the drug candidate. For example, the efficacy or toxicity of a drug candidate can be evaluated by comparing the characteristics of cells when the drug candidate is contacted with the cells with those when the drug candidate is not contacted with the cells.
The present invention will be further specifically described by the following examples, but the present invention is not limited by the examples.
Examples
In examples 1 to 5, a meniscus injury model was prepared, and specific proteins necessary for drug efficacy were identified and confirmed by blocking specific protein molecules necessary for therapeutic effects by synovial stem cells. As a method of blocking a specific protein molecule, a method using a cell blocked by an antibody against a specific protein molecule or a method using a cell deleted from a specific protein molecule by gene knockout is used, and when the meniscus regenerating effect is significantly reduced, a specific protein molecule necessary for drug efficacy can be confirmed.
Example 1: preparation of synovial stem cells as therapeutic cells
In the establishment of synovial-derived mesenchymal stem cells, 5-week-old Lewis rats were used. Regarding synovial tissue collected under isoflurane anesthesia, to a culture medium containing Fetal Bovine Serum (fetal bovine serum) (GibcoCat.# 10270) at a concentration of 20% and anti-Antibiotic-Antimycotic (100X) (Thermofisher Scientific Cat.# 15240062) at a concentration of 1%, mem alpha with L-Alanyl-L-Glutamine, phenol Red and Sodium Pyruvate (mem alpha containing L-Alanyl-L-Glutamine, phenol red, and sodium pyruvate) (FUJIFILM WAKO Cat.# 282-98675) was added collagamev (collagenase V) (Sigma Cat#C9263) at a concentration of 1%, and the reaction was carried out at 37℃for 2 hours. Cooled medium was added to stop the reaction and passed through a 40 μm cell filter to remove residual tissue. Sowing the recovered cells to 75cm 2 In a cell culture flask (Corning Incorporated, model: 353136), in CO 2 The culture was carried out at a concentration of 5% and a temperature of 37℃for 8 days. After 8 days of culture, the medium in the flask was discarded, and after 2 washes with Phosphate Buffer (PBS), 4mL of TrypLE Express (Thermo Fisher) was added, allowed to stand in an incubator at 37℃for 5 minutes, and the CELLs were recovered as mesenchymal stem CELLs, and the number of CELLs was calculated using a living and dead CELL automatic analyzer Vi-CELL (BECKMAN COULTER, model: 731050). The supernatant was discarded by centrifugation and replaced with COS-bank, thereby preparing a frozen stock of synovial stem cells.
Example 2: manufacturing of meniscus injury model
In the preparation of a meniscus injury model for evaluation of meniscus regeneration effect, 10 week old Lewis rats were used. Regarding the method of transplanting meniscus injury and mesenchymal stem cells, the knee skin is incised under isoflurane anesthesia to expose the knee. Exposing medial joint capsule under knee and longitudinally using surgical knifeCut to expose cartilage of the distal femoral portion. The medial meniscus was peeled from the synovium to expose the medial meniscus and the entire approximately 2/3 was resected. The knee tendons and synovium were sutured, followed by suturing the muscles. After the meniscus injury was treated, it was divided into 2 groups of mesenchymal stem cells (synovial stem cells) derived from rat synovium prepared in example 1 and PBS group as a control. In the synovial stem cell group, the mesenchymal stem cells were given by waking up and culturing the cells established and frozen by the synovial membrane in a culture medium of mMEM alpha with L-Alanyl-L-Glutamine, phenol Red and Sodium Pyruvate (FUJIFILM WAKO Cat # 282-98675) supplemented with 20%Fetal Bovine Serum (Gibco Cat # 10270), 1% anti-animal (100X) (Thermofisher scientific Cat # 15240062) for 1 week, and the number of recovered cells was 5X10 using a syringe needle 6 Cells (cells) are inserted into the knee from the suture site to the puncture needle in a direction perpendicular to the knee, and the skin is sutured. After the surgery, all rats were returned to the cage and allowed free movement and diet. Animals were examined by dissection 3 weeks after treatment. Animals were euthanized by dissecting the aorta under isoflurane anesthesia to allow exsanguination. Thereafter, the knee joint was removed to expose the meniscus, the medial meniscus was removed, and a photograph was taken. An image of the medial meniscus of the knee removed is shown in fig. 1. Based on the differences in hue and shape from the normal meniscus, a regenerated portion is determined from the image and surrounded by lines. In the PBS group, the meniscus has half the shape up to the middle node, but in the synovial stem cell group, an example of a plurality of menisci regenerating to the anterior node was observed, and therefore, the meniscus regenerating effect by the synovial stem cell transplantation was confirmed.
To quantitatively compare the meniscus regeneration effect in the synovial stem cell group and the PBS group, the area of the meniscus regeneration portion (in-line) was measured using ImageJ (version 1.52). The meniscus regeneration portion was visually judged based on the hue and shape of the meniscus, and the area was calculated by the following formula.
Meniscus regeneration partial area (mm) 2 ) Number of pixels per 1mm of meniscus regeneration partial region 2 Is the number of pixels of (a)
The average value, standard deviation and statistical analysis of the regenerated part area of each group were performed by Microsoft Excel (registered trademark) 2007 (Microsoft Corporation). For statistical analysis, student's T-Test was performed between synovial stem cell group and PBS group, and significant levels of less than 5% (P < 0.05) were set as differential.
The values of the meniscus regeneration partial area of the synovial stem cell group and the PBS group are shown in table 1. Meniscus regeneration section area of PBS group was 1.1mm 2 While the area of the meniscus regenerative part of the synovial stem cell group was 2.0mm 2 With a regeneration area of about 2 times, a statistically significant difference (P < 0.01) was shown. Thus, it was confirmed that synovial stem cells have a therapeutic effect of meniscus regeneration. In the following examples, specific protein molecules necessary for drug efficacy were identified and confirmed by administering cells that block the specific protein molecules to the meniscus injury model described in this example.
TABLE 1
Table 1: area of meniscus regeneration section (mean ± standard deviation)
Group of Meniscus regeneration partial area (mm) 2 )
PBS group n=5 (10 knee) 1.1±0.9
Synovial stem cell group n=5 (10 knee) 2.0±0.8*
* PBS group with P less than 0.05vs
Example 3: preparation of synovial stem cells that hinder specific proteins and evaluation of efficacy in a model of meniscus injury
With respect to the synovial stem cells obtained in example 1, a neutralizing antibody against the surface antigen CD29 (BioLegend cat#102202), a neutralizing antibody against the surface antigen CD140b (R & D Systems cat#af 385), and a neutralizing antibody against the surface antigen CD44 (Absolute Antibody Cat #ab 00628-23.0) were prepared and incubated with the synovial stem cells one by one, thereby preparing synovial stem cells that block the specific protein molecules. The cell lines were set to be CD 29-restricted synovial stem cells, CD140 b-restricted synovial stem cells, and CD 44-restricted synovial stem cells, respectively. Meanwhile, igG-responsive synovial stem cells obtained by incubating IgG showing no molecular obstruction to synovial stem cells with synovial stem cells were prepared as controls. These cells were administered to a meniscus injury model in the same manner as in example 2, and the area of the meniscus regenerated portion after 3 weeks was obtained in the same manner as in example 2. The results are shown in fig. 2.
As a result, it was found that the effect of CD29 blocking synovial stem cells on meniscus regeneration treatment was statistically significantly lost as compared with IgG-responsive synovial stem cells. Similarly, it was found that the effect of CD140b blocking synovial stem cells on meniscus regeneration treatment was also statistically significantly reduced compared to IgG-responsive synovial stem cells. Thus, it is possible to identify a specific protein molecule or the like necessary for the efficacy of CD29 or CD140 b. On the other hand, the inhibition of synovial stem cells by CD44 was not confirmed to significantly reduce the therapeutic effect on meniscus regeneration compared to IgG-responsive synovial stem cells. Thus, CD44 cannot be said to be a specific protein molecule necessary for drug efficacy.
Example 4: preparation of synovial stem cells deleted for specific proteins by Gene knockout and evaluation of efficacy in a model of meniscus injury
Relative to the synovial stem cells obtained in example 1, gene knockout was performed on TNFαR1, VCAM1, col2a1 alone. Thus, as synovial stem cells in which specific protein molecules of tnfα R1, VCAM1, col2a1 were individually eliminated, tnfα R1-depleted synovial stem cells, VCAM 1-depleted synovial stem cells, col2a 1-depleted synovial stem cells were prepared. In this regard, using the meniscus injury model, the meniscus regeneration effect was compared with tnfα R1WT synovial stem cells, VCAM1WT synovial stem cells, col2a1WT synovial stem cells, which were control cells without knockout. Regarding evaluation of the meniscus regenerating effect, each cell was given to the meniscus injury model in the same manner as in example 2, and the area of the meniscus regenerating portion after 3 weeks was obtained in the same manner as in example 2. The results are shown in fig. 3.
As a result, tnfα R1 knocked out synovial stem cells were not statistically significantly different from those without knockout, and the meniscus regeneration treatment effect was not reduced. Compared with the synovial stem cells without elimination, the VCAM1 elimination synovial stem cells have no statistically significant difference, and the meniscus regeneration treatment effect is not reduced. Thus, it is clear that TNFαR1 and VCAM1 cannot be regarded as specific protein molecules necessary for drug efficacy. On the other hand, col2a1 knocked out synovial stem cells were accompanied by statistically significant differences and a concomitant decrease in meniscus regeneration treatment effect, as compared to synovial stem cells that were not knocked out. Thus, col2a1 is a specific protein molecule and the like necessary for drug efficacy.
Example 5:
the positive rate of CD29 and CD140b, which are protein molecules necessary for the specific drug effect in example 3, was measured by flow cytometry with respect to the synovial stem cells obtained in example 1. As antibodies, CD29 (PE Anti-mouse/rat CD29 Anti-Antibody), bioLegend cat#102207, CD140b (Anti-PDGF Receptor β (Anti-platelet derived growth factor Receptor β), human (Human), coat-Poly, R & D Systems cat#af 385) were used, respectively.
As a result, it was found that the surface antigen positive rate of CD29 was 98.7% and the surface antigen positive rate of CD140b was 91.6%. Thus, it is found that it is appropriate to manage the standard value to 90% or more in CD29 and 80% or more in CD140 b.
In addition, regarding human synovial-derived stem cells (Cryopreserved Synoviocytes (cryopreserved synovial cells), normal (Normal), model P1: CDD-H-2910-N, lots: ST1414, ST1420, ST1434, ST 1462) purchased from Articular Engineering, LLC, the positive rates of CD29, CD140b, which are protein molecules necessary for drug efficacy, were also measured by flow cytometry. As antibodies, CD29 (APC Mouse Anti-Human CD29 Cat): 559883), CD140b (Anti-PDGF Receptor beta (Anti-platelet derived growth factor Receptor beta), human (Human), goat-Poly Cat: AF 385) were used, respectively.
As a result, the surface antigen positive rate of CD29 was 99.4%, 99.6% and 99.5% in each batch. The surface antigen positive rate of CD140b was 92.2%, 90.7%, 95.2% and 85.9% in each batch. Thus, it is found that it is appropriate to manage the standard value to 90% or more in CD29 and 80% or more in CD140 b.
In examples 6 to 10 below, whether or not the drug effect is necessary, it was confirmed that the cell populations were managed separately from the correlation by selecting the relevant genome expressions that characterize the cell populations and using their genome expression patterns.
Example 6: cell preparation and mRNA sample preparation for each cell
Example 6-1: preparation of MSC cells and mRNA thereof
(1) Cells
The following cells were prepared.
Synovial MSC: preparation of synovial stem cells (commercially available) (4 Lot)
Stem cells derived from frozen synovial membranes (Cryopreserved Synoviocytes (cryopreserved synovial cells), normal, model P1: CDD-H-2910-N, lot: ST1414, ST1420, ST1434, ST 1462) purchased from Articular Engineering, LLC were used.
L bone marrow MSCs: preparation of mesenchymal Stem cells derived from bone marrow (manufactured by Lonza) (3 Lot.)
Bone marrow-derived mesenchymal stem cells (model Mesenchymal Stem cells cryo amp (mesenchymal stem cells were cultured at low temperature): PT-2501, batch: 18TL241909, 0000494678, 19TL 155677) purchased from LONZA were used.
J bone marrow MSCs: preparation of mesenchymal Stem cells derived from bone marrow (manufactured by J-TEC) (3 Lot.)
Bone marrow-derived mesenchymal stem cells (batch: BKXH) prepared in Japan Tissue Engineering Co., ltd (J-TEC) were used.
F bone marrow MSCs: preparation of mesenchymal Stem cells derived from bone marrow (manufactured by FF) (3 Lot.)
Mesenchymal stem cells derived from bone marrow obtained by isolation from bone marrow fluid (Whole Bone Marrow (whole bone marrow), fresh, 10mL, model: ALL-ABM001, batch: 3024624, 3024625) purchased from Allcels were used.
REC-MSC: preparation of mesenchymal Stem cells derived from bone marrow (REC: manufactured by PuREC) (3 Lot.)
Ultra-high purity human mesenchymal stem cells (REC) purchased from PuREC corporation (model: 387-16591, batch: 050780614, 200370207, 111090605) were used.
iPSC-MSC: preparation of mesenchymal Stem cells derived from iPSC (manufactured by FCDI) (1 Lot.)
The iCell mesenchymal stem cells purchased from FUJIFILM Cellular Dynamics, inc. (model: R1098, batch: 0004) were used.
L fat MSC: preparation of adipose-derived mesenchymal Stem cells (manufactured by Lonza) (3 Lot.)
Adipose-derived mesenchymal stem cells (adiose-Derived Stem cells (Adipose-derived stem cells) (amp) model: PT-5606, lot: 18TL241909, 0000494678, 19TL 155677) purchased from LONZA were used.
(2) Culture medium
To the basal medium: to MEM alpha (containing L-Alanyl) -L-glutamine, phenol red, sodium pyruvate) (model: 289-33365, batch: SKH 9471) were added gentamycin sulfate ("TAKATA Pharmaceutical Co., ltd., gentamicin Injection (60% for Gentamicin pharmaceutical use) as an antibiotic in such a manner that the final concentration became 15% (v/v), 20. Mu.g/mL, and fetal bovine serum (model: FBS-04 from Selbore Co., ltd.) were used. Hereinafter, the above-mentioned medium is referred to as a culture medium.
(3) Isolation of mesenchymal Stem cells derived from bone marrow fluid (mesenchymal Stem cells derived from bone marrow fluid of Allcels Co.)
About the roomIsolation of mesenchymal Stem cells, centrifugation of the purchased bone marrow fluid (batch: 3024624, 3024625) was carried out at 1000rpm for 10 minutes, and the culture medium was added to the plasma-removed material in an amount 10 times that before plasma removal, and was set at 0.20mL/cm 2 Sowing it into flask at 37deg.C, 5% CO 2 The culture was performed in an incubator under the environment. The medium was changed every 3 days or 4 days, and after culturing for 12 to 13 days after seeding, the medium was peeled off with 0.05% trypsin-EDTA (ethylenediamine tetraacetic acid) solution (hereinafter, trypsin, model Life Technologies: 25300). After stripping, trypsin neutralization was performed with an equal amount of medium and transferred to a separately prepared tube. The culture flask was further washed with an equal amount of medium, added to the above test tube, and the remaining cells were recovered. The tube was centrifuged at 200 Xg for 5 minutes and the supernatant removed. An appropriate amount of medium was added to the remaining particles and cell counts were performed using a hemocytometer. So that the final concentration is 0.20 to 0.50X10 4 Cells/cm 2 Is sown into flasks at 37℃with 5% CO 2 The culture was performed in an incubator under the environment. Culturing for 3 or 4 days, repeatedly passaging by the same procedure as above when the cells are filled with more than 60% of the bottom surface of the flask, centrifuging the cells at the end of the 2 nd passaging, and adjusting the freezing solution obtained by mixing with the culture medium to 100×10 4 cells/mL so that the final concentration was 10% (v/v) dimethyl sulfoxide (SIGMA-ALDRICH model: D2650).
(4) Culture of mesenchymal stem cells and extraction of genes
The recommended media for the mesenchymal stem cells (the 7 types and 17 batches in total) were different from one another, but in order to reduce the influence of the media on the genetic analysis, each cell was cultured using the medium described in (2) above. Thawing frozen stock of each MSC in water bath at 37deg.C, centrifuging at 200×g for 5 min, removing frozen liquid, adding each culture medium, and making into final product of 0.25-0.50X10 4 Cells/cm 2 Is sown into flasks at 37℃with 5% CO 2 In the environmentThe culture was performed in the incubator for 3 days or 4 days. When the cells were filled to 60% or more of the bottom surface of the flask, 2 passages were performed by the above method. The cells thus collected were subjected to Lysis Buffer (Lysis Buffer) to which DTT (Wako, 047-08973) was added to QIAGEN RNeasy (QIAGEN, 74104) RLT Buffer, and the mixture was stirred by pipetting to prepare a Lysate (Lysate), which was stored at-80 ℃. For RNA extraction, the extraction was performed according to QIAGEN protocol. The obtained RNA aqueous solution was subjected to nucleic acid concentration measurement and dilution as necessary.
Example 6-2: preparation of non-MSC cells and mRNA thereof
(1) Cells
The following cells were prepared.
LONZA Fibroblast (FB) CC-2509
ATCC Pulmonary Artery Endothelial Cell (PAEC) PCS-100-022
Visceral adipocyte (WP) C-12732 from Promocell Corp
Chondrocyte (CH) C-12710 from Promocell
Promocell corporation hematopoietic precursor cells (CD 34 cells) C-12921
LONZA company T cell (Tcell) 2W-200
ATCC B cell (Bcell) PCS-800-018
Promocell Co mononuclear sphere (CD 14 cells) C-12909
Peripheral blood derived iPSC cells (iPSC)
(2) Preparation and Gene extraction of cells other than mesenchymal Stem cells
Regarding fibroblasts, pulmonary artery endothelial cells, visceral adipocytes, chondrocytes, hematopoietic precursor cells, mononuclear spheres, after melting the frozen vials in a 37 ℃ water bath and slowly adding to 10mL of medium of warmed MEM alpha/15% fbs/20 μg/mL gentamicin, cell counts were performed. After centrifugation (300 xG, 5 minutes, room temperature), the supernatant was removed as much as possible, and a lysis Buffer to which DTT (Wako, 047-08973) was added to the RLT Buffer of QIAGEN RNeasy (QIAGEN, 74104), followed by pipetting and stirring, thereby preparing a lysate. The lysate was transferred in 350. Mu.L units to a 1.5mL tube (tube) and used for RNA extraction.
T cells were melted in a 37 ℃ water bath and transferred to a 50ml conical tube (medical tube). To this was slowly added warmed RPMI/NEAA/1mmol/L Sodium Pyruvate (sodium pyruvate)/2 mmol/L L-Alanine & L-Glutamine (L-alanyl & L-Glutamine)/10 mmol/LHEPES/10% FBS/20U/mL DNaseI (1 mL). 1mL of the above-mentioned medium heated was placed in an empty bottle, and the rinse solution was repeatedly added to a 50mL test tube for several drops, followed by gentle stirring, and the whole was added over 1 to 2 minutes. After a few drops of the above medium were repeatedly added thereto, the mixture was gently stirred, and the mixture was added over several minutes until the final volume became 50mL. After cell counting, centrifugation (300 xG, 5 min, room temperature) was performed, the supernatant was removed as much as possible, RLT/DTT+ was added, and stirring was performed by Pipetting (stirring). The lysate was transferred in 350. Mu.L units to a 1.5mL tube (tube) and used for RNA extraction.
For B cells, cell counts were performed after melting the frozen vials in a 37 ℃ water bath and slow addition to warmed HBSS/10& hsa (5 mL). After centrifugation (300 xG, 5 min, room temperature), the supernatant was removed as much as possible, RLT/DTT+ was added, and agitation was performed by pipetting. The lysate was transferred in 350. Mu.L units to a 1.5mL tube (tube) and used for RNA extraction.
iPS cells were cultured on a 6well plate (well plate), and RLT/dtt+350 μl/well was added after removing the supernatant, and lysed by pipetting. 1well of lysate was added to 1.5mL tube for RNA extraction.
The number of cells used in 1 time of RNA extraction is not more than 4x10 6 And each. In addition, when RNA extraction is not performed immediately after preparation of the lysate, the lysate is stored at-80℃and melted on ice for RNA extraction on the day of RNA extraction. For RNA extraction, the extraction was performed according to QIAGEN protocol. The obtained RNA aqueous solution was subjected to nucleic acid concentration measurement and dilution as necessary.
Example 7: gene expression Pattern Gene pack production
(1) Selection of characteristic genomes in MSC
Amplicon sequence (amplicon sequence) can be measured with high accuracy if it is 1200 genes or less. Therefore, the function or state of MSC, the gene used as a marker was reduced to 1200 genes, and a high throughput evaluation system was constructed. As items for evaluating the function/status of MSC, 16 items were selected as items related to MSC with reference to gene packages of gene expression analysis sold in the market (table 2).
As a method for selecting genes, a commercially available gene pack (Thermo Fisher Scientific Inc., illumina, QIAGEN, bio-Rad Laboratories), literature, microarray data, and a body database (http:// www.informatics.jax.org/vocab/gene_ontology /) was used for each of 16 items to select genes with a high occurrence frequency.
TABLE 2
Table 2: MSC-related items and target base factors in commercial Gene packages
As a result, the genes were selected based on 26 commercially available gene packages, 294 documents, a body database, and microarray data by prioritizing the occurrence frequencies. The result of sorting the repeated genes for each item can extract 1107 genes in total. Further, 92 genes were selected from the microarray data. As the remaining 1 gene, GAPDH was selected as a housekeeping gene, totaling 1200 genes. The selection method of the gene and the selected gene of each item are shown below.
< 1 > selection of genes involved in bone formation
84 species were extracted from PAHS-049Z"Osteogenesis PCR Array (osteogenic PCR array) of QIAGEN, 392 species were extracted from the ontology database (Osteogenesis), 92 species were extracted from 23 documents related to MSC/Osteogenesis), and 477 species of genes were extracted in total. 11 differentiation predictive markers were added, and 96 genes were selected by prioritizing the sequences in order of high frequency of occurrence.
< 2 > selection of adipogenesis-related genes
84 species were extracted from PAHS-026Z"Adipogenesis PCR Array (Adipogenesis PCR array) of QIAGEN, 270 species were extracted from an ontology database (Adipogenesis), 97 species were extracted from 23 documents related to MSC/Adipogenesis), and 354 species were extracted in total. 9 differentiation predictive markers were added, and 101 genes were selected in order of priority with high frequency of occurrence.
< 3 > selection of cartilage formation related Gene
There are no commercially available genetic packages associated with cartilage, and therefore, are selected based on the body database, R & d systems cartilage markers, literature, cartilage matrix. 214 species were extracted from the ontology database (Chondrogenesis), 30 species were extracted from the website (web site) of R & D systems, 249 species were extracted from papers (52) related to MSC/chondrogenies, 14 species were extracted from the cartilage matrix, and 398 species of genes were extracted in total. 119 genes were selected according to the order of priority of the high frequency of occurrence.
< 4 > selection of immune-related genes
Genes selected from the following 3 gene packages (QIAGEN company PAHS-052Z "Innate)&Adaptive Immune Response PCR Array (congenital)&Adaptive immune response PCR array) "84, thermo Fisher Scientific Inc.#4414073" taqman TM Array Human Immune Response(TaqMan TM Array human immune response) "96 kinds, illumina company #20019169"AmpliSeq for Illumina Immune Response Panel (AmpliSeq) of Illumina immune response gene package) "401 kinds, 107 kinds of MSC/immune related literature 15 were extracted, and 512 kinds of genes were extracted in total. 282 genes were selected in order of priority in order of high frequency of occurrence.
< 5 > selection of inflammation-related Gene
798 of the following 6 gene packages (QIAGEN PAHS-011Z"Inflammatory Cytokines)&Receptors PCR Array (inflammatory cytokines)&Acceptor PCR array) ", QIAGEN company PAHS-3803Z"Inflammatory Response and Autoimmunity 384H (inflammatory response and autoimmune 384H) ", thermo Fisher Scientific Inc. EPX200-12185-901"Inflammation 20-Plex Human ProcartaPlex TM Panel (inflammation 20-Plex human ProcartaPlax) TM Gene pack) ", illumina company #20020496"AmpliSeq for Illumina RNA Inflammation Response Research Panel (AmpliSeq of Illumina RNA inflammatory response study group) ", bio-Rad Laboratories #171AL001M" Bio-Plex Pro human Inflammation analysis kit "(Bio-Plex Pro human Inflammation analysis kit)", and Bio-Rad Laboratories #12007283"Bio-Plex Pro" TM Human cytokine screen 48-Plex gene pack "), 715 from the body database (inflammatory response (inflammatory response)), 110 from literature 29 related to MSC/anti-inflammation, and 1257 genes in total. 303 genes are selected according to the order of priority of the high frequency of occurrence.
< 6 > selection of angiogenesis-related Gene
166 (QIAGEN PAHS-024Z"Angiogenesis PCR Array (angiogenic PCR array)", QIAGEN PAHS-072Z"Angiogenic Growth Factors PCR Array (angiogenic growth factor PCR array)", thermo Fisher Scientific Inc.#4414071 "TaqMan" were extracted from the following 3 commercially available gene packages TM Array Human Angiogenesis(TaqMan TM Array human angiogenesis) ") from an ontology database (angiogensis: angiogenesis), 531 species were extracted, 179 species were extracted from document 15 related to MSC/angiogenin, and 647 species of genes were extracted in total. 121 genes were selected in order of priority of high frequency of occurrence.
< 7 > selection of nerve regeneration related Gene
From the following 3 commercially available gene packages, 246 (QIAGEN PAHS-404Z"Neurogenesis PCR Array (neurogenic PCR array)" 84, QIAGEN PAHS-031Z"Neurotrophin and Receptors PCR Array (neurotrophic factor and receptor PCR array)" 84 and Thermo Fisher Scientific Inc. #4414094 "TaqMan" were extracted TM Array Human Neurotransmitters(TaqMan TM Array human neurotransmitter) "92), 80 from the body database (nerve development (neural development)), 92 from document 16 related to MSC/nerve regeneration, and 380 genes in total. 109 genes were selected in the order of priority of high frequency of occurrence.
< 8 > selection of fibrosis related genes
84 kinds of the DNA were extracted from QIAGEN PAHS-026Z"Fibrosis PCR Array (fibrosis PCR array) and from the body database; collagen metabolic process (collagen metabolism) (GO: 0032963), fibroblast proliferation (fibroblast proliferation) (GO: 0048144), connective tissue replacement (connective tissue substitution) (GO: 0097709), fibroblast migration (fibroblast migration) (GO: 0010761) were extracted 268 species, 59 species from document 19 related to MSC/fibritis, and 346 species of genes in total were extracted. 112 genes were selected in order of priority in order of high frequency of occurrence.
< 9 > selection of immunogenicity-related genes
Since there is no commercially available genetic package related to immunogenicity, a total of 42 genes were selected from literature 20.
< 10 > selection of migration-related genes
84 species were extracted from the QIAGEN company PAHS-128Z"Cell Motility PCR Array (cell movement PCR array)' from the body database; negative regulation of cell migration (negative regulation of cell migration) (GO: 0030336), positive regulation of cell migration (positive regulation of cell migration) (GO: 0030335), regulation of cell migration (regulation of cell migration) (GO: 0030334), mesenchymal stem cell migration (mesenchymal stem cell migration) (GO: 1905319) 925 species were extracted, 137 species were extracted from 15 pieces of MSC/migration-related literature, and 199 species were extracted in total. However, since the number of genes in the body is large, genes that occur only in the body are excluded. 137 genes were selected in order of priority of high frequency of occurrence.
< 11 > selection of adhesion-related Gene
#4418778"TaqMan from Thermo Fisher Scientific Inc TM Array,Human Extracellular Matrix&Adhesion Molecules(TaqMan TM Array, human extracellular matrix&Adhesion molecules) "92 species were extracted from the bulk database; cell adhesion mediated by integrin (integrin-mediated cell adhesion) (GO: 0033627), negative regulation of cell adhesion (negative regulation of cell adhesion) (GO: 0007162), positive regulation of cell adhesion (positive regulation of cell adhesion) (GO: 0045785), regulation of cell adhesion (regulation of cell adhesion) (GO: 0030155) were extracted from the other 14 items 952, 78 from literature 16 related to MSC/adhesion/implantation, 34 as adhesion molecules, and 138 genes in total were extracted. However, since the number of genes in the body is large, genes that occur only in the body are excluded. 95 genes were selected in order of priority with high frequency of occurrence.
< 12 > selection of aging-related genes
163 (QIAGEN PAHS-178Z"Aging PCR Array (aged PCR array)" 84 (QIAGEN PAHS-050Z"Cellular Senescence PCR Array (cell aged PCR array)" 84) were extracted from the following 2 commercially available genetic packages), and from the bulk database; 153 species were extracted from Cell aging (GO: 0007569), 273 species were extracted from MSC/aging-related literature 20, and 493 species were extracted in total. 113 genes were selected in order of priority in order of high frequency of occurrence.
Selection of genes related to growth factors and cytokines of < 13 > < 14 >, respectively
The genes in the projects of growth factors and cytokines are similar, so comprehensive selection is performed.
144 kinds of gene packages (QIAGEN PAHS-041Z"Growth Factor PCR Array (growth factor PCR array)" 84 kinds and QIAGEN PAHS-150Z"Cytokines and Chemokines PCR Array (cytokine and chemokine PCR array)" 84 kinds) were extracted from 2 kinds of gene packages commercially available below, 205 kinds of gene packages were extracted from 15 pieces of documents related to growth factors and cytokines secreted from MSC, and further, 35 kinds of gene packages were extracted from the supernatant of MSC obtained by passaging J bone marrow MSC, F bone marrow MSC and iPSC-MSC to P6 by the above-mentioned method using Proteome Profiler Human XL Cytokine Array Kit (proteasome Profiler human XL cytokine array kit) (model: ARY 022), and 38 kinds of gene packages were extracted from cytokines detected by LAS-3000 (general electric medical group) in total, and 350 kinds of genes were extracted. 177 genes were selected in order of priority with high frequency of occurrence.
< 15 > selection of MSC marker-related genes
84 species were extracted from PAHS-082Z"Mesenchymal Stem Cell PCR Array (mesenchymal Stem cell PCR array) of QIAGEN, 165 species were extracted from document 16 related to MSC markers, and 212 species of genes were extracted in total. 110 genes were selected in order of priority of high frequency of occurrence.
< 16 > selection of surface marker-related genes
From 90 of the QIAGEN PAHS-055Z"Cell Surface Markers PCR Array (cell surface marker PCR array)," 101 of the candidate genomes not selected from the MSC markers, and further from the BD company Lyoplate TM Human Cell Surface Marker Screening Panel(Lyoplate TM Human cell surface marker screening gene pack) (model: 560747 Data obtained by comprehensively analyzing 242 surface markers of MSC obtained by passaging J bone marrow MSC, F bone marrow MSC, and iPSC-MSC to P6 by the above-described method was given priority from 2 viewpoints of high positive rate (50% or more) and large difference in value between samples (50% or more). The operation was carried out as a protocol and tested with an Attune NxT of Thermo Fisher Scientific inc. 348 genes were extracted in total. 87 genes were selected in order of priority with high frequency of occurrence.
< selected 1200 Gene >)
ABCB1 (ATP-binding cassette, sub-family B (MDR/TAP), membrane 1A: ATP-binding cassette, subfamily B (MDR/TAP), member 1A), abl1 (c-Abl oncogene 1, non-receptor tyrosine kinase: c-Abl oncogene 1, non-receptor tyrosine kinase), ACACB (acetyl-Coenzyme Acarboxylase beta: acetyl-coa beta decarbonylase), acan (aggrecan: aggrecan), ACHE (actyloline esterase: acetylcholinesterase), ackr2 (atypical chemokine receptor: atypical chemokine receptor 2), ackr3 (atypical chemokine receptor: atypical chemokine receptor 3), ACLY (ATP citrate lyase: ATP citrate lyase), ACTA2 (Actin, alpha 2,smooth muscle,aorta: actin, alpha 2, smooth muscle, aorta), ACTB (actl, beta: actin, beta), ACTG2 (Actin, gamma2, smooth muscle, skin muscle, entry, gamma2, smooth muscle, intestinal cyst), ACTN3 (Actin alpha 3: auxiliary Actin alpha 3), ACTR2 (ARP 2 Actin-related protein 2: ARP2 Actin related protein 2), ACTR3 (Actin-released protein 3 ARP3 related protein 3), acvr1 (activin Areceptor, type 1: activin, type 1), actl 2: gamma2, intestinal cyst), ACTN3 (actlin receptor 2: gamma2, gamma 2), actlin receptor (6736 IIA), and receptor IIA (gamma 2: activated receptor activin receptor IIB, gamma2, gamma receptor IIB, gamma2, gamma receptor 2, actl 2, actl, ACTR2, ACTR3 (alpha 3, beta 2 beta, beta gamma, beta gamma beta, ADAMTS1 (a disconterin-like and metallopeptidase (reprolysin type) with thrombospondin type 1motif,1: disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motifs), ADAMTS5 (a disconterin-like and metallopeptidase (reprolysin type) with thrombospondin type 1motif, 5 (aggrectanase-2): disintegrin-like and metallopeptidase (reprolyase type), 5 (polyproteinase-2) with thrombospondin type 1 motifs), adgrb1 (adhesion G protein-coupled receptor B1: adhesion G protein coupled receptor B1), adigin (adipogenin: adipogenesis), adipoq (adiponectin, C1Q and collagen domain containing: adiponectin, domain containing C1Q and collagen), adora1 (adonine A1 receptor: adenosine A1 receptor), adora2a (adonine A2 receptor: adenosine A2 receptor), adorb 2 (adrenergic receptor, beta 2: epinephrine receptor, beta 2), afap1l2 (actin filament associated protein-like 2: actin fiber related protein 1-like 2), ager (advanced glycosylation end-product specific receptor: advanced glycation end product specific receptor), agRP (Agouti related protein: murine related protein), agagin (aglutinin a (83 a), serine a (92-serine A2 receptor), alpha-1-alpha-glycoprotein, alpha-1 receptor, alpha-alpha 2, alpha-glycoprotein inhibitor (wear-8) and human vascular graft factor (HS-1-37-8) are included in the present invention Aimp1 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 1: aminoacyl tRNA synthetase complex interaction multifunctional protein 1), akt1 (thymoma viral proto-oncogene 1: thymoma viral oncogene 1), akt3 (thymoma viral proto-oncogene 3: thymoma virus oncogene 3), alcam (activated leukocyte cell adhesion molecule: activated leukocyte adhesion molecule), alox15 (arachidonate 15-lipoxygenase), alox5 (arachidonate 5-lipoxygenase), alox5ap (arachidonate 5-lipoxygenase activating protein: arachidonate 5-lipoxygenase activation protein), alplica (alkaline phosphatase, lip/bone/knee: alkaline phosphatase, liver/kidney), AMOT (Angiogenin: angiogenin), angin 2 (anggin 2: ANGEL homolog), angin 1 (anggin 1: angiogenin 1), angin 2 (anggin 2: angiogenin 2), angin 4: angiogenin 2), angin 3 (anggin 4: anggin 3-4A membrane (anggin 3: anggin 3-4A membrane-anggin-4, anggin-3 (anggin-4: anggin-3-2), angin-2 (anggin-2: anggingin 2: anggingingin 1), angingin 2: anggingingingingin 2: anggingingingin 2, anggingingingingingin 2, anggingingingingingingin 2-ang2-angginang2-angginginginang2-angginang2-ang2-angangangangangangangangang2 A2 AangangangangangangA2 AangAangAangAangAangAAAAangAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA- -A5 5, anxa6 (annexin A6: annexin A6), aoah (acyloxyacyl hydrolase: acyloxyacyl hydrolase), aoc3 (amine oxidase, copper containing: amine oxidase, copper-containing 3), APAF1 (apoptotic peptidase activating factor: apoptotic peptidase activator 1), APBA1 (amyl beta (A4) precursor protein binding, family A, member 1: amyloid beta (A4) precursor protein binding, family A, member 1), APBA2 (amyloid beta (A4) precursor protein-binding, family A, member 2: amyloid beta (A4) precursor protein binding, family A, member 2), apoa1 (apoipoprotein A-I), lipoprotein element A-I,
APOE (apoipitoprotein E: lipoprotein element E), areg (Amphigregulin: amphiregulin), ARF6 (ADP-ribosylation factor: ADP ribosylating factor 6),
ARG1 (arginase, liver), ARG2 (arginase type II arginase, type II), arhgap29 (Rho GTPase activating protein: rho-GTPase activating protein 29), ARHGAP35 (Rho GTPase activating protein: rho-GTPase activating protein 35), ARL6IP6 (ADP-ribosylation factor-like 6interacting protein 6:ADP ribosylating factor-like 6interacting protein 6), artn (Artemin: artesunate), atm (ataxia telangiectasia mutated: telangiectasia ataxia mutation), atrn (attgear: attractin), AURKB (aurora kinase B), aurora kinase B),
Axin1 (Axin 1: aurora 1), axl (AXL receptor tyrosine kinase: AXL receptor tyrosine kinase), B2M (beta-2 microglobulin: beta-2 microglobulin), B3gat1 (beta-1, 3-glucoronyltransferase 1: beta-1,3-glucuronyl transferase 1), B4GALNT1 (beta-1, 4-N-acetyl-galactosaminyl transferase 1: beta-1, 4-N-acetyl-galactosyltransferase 1), B4galt1 (UDP-Gal: betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1: UDP-Gal: beta-GlcP-1, 4-galactosyltransferase, polypeptide 1), BAIAP2 (brIAP-specific angiogenesis inhibitor-associated protein: brain-specific angiogenesis inhibitor 1-related protein), BCR 1 (BCR 35-98: BCR 1/35) and B4 galenical 1 (BcPhoma 35/78), bcPhoma-6/38 leukemia cell leukemia resistance to BcPhoma/38B 2,
Bdkrb1 (bradykinin receptor, beta 1: bradykinin receptor, β1), bdkrb2 (bradykinin receptor, beta 2: bradykinin receptor,. Beta.2), BDNF (Brain-derived neurotrophic factor: brain-derived neurotrophic factor), bglap (bone gamma carboxyglutamate protein: bone-containing gamma-carboxyglutamate), BGN (biglycan: dimeric sugar), BMI1 (Bmi 1 polycomb ring finger oncogene: BMI1 multicartridge nameless oncogene), bmp1 (bone morphogenetic protein 1: bone morphogenetic protein 1), bmp2 (bone morphogenetic protein: bone morphogenetic protein 2), bmp3 (bone morphogenetic protein 3: bone morphogenetic protein 3), bmp4 (bone morphogenetic protein 4: bone morphogenetic protein 4), bmp5 (bone morphogenetic protein: bone morphogenetic protein 5), bmp6 (bone morphogenetic protein 6: bone morphogenetic protein 6), bmp7 (bone morphogenetic protein: bone morphogenetic protein 7), bmpr1A (bone morphogenetic protein receptor, type 1A: bone morphogenetic protein receptor, type 1A), bmpr1B (bone morphogenetic protein receptor, type 1B: bone morphogenetic protein receptor, type 1B), bmpr2 (4, type II (serine/serine) (bone morphogenetic protein: bone morphogenetic protein 5), bmp6 (75) bone morphogenetic protein (75) and human bovine bone-cell receptor (B) type, B1 (B, B1: bone morphogenetic protein B) type, B (B, B2 (B2) type, B2 (B2) serine (B) protein (bone morphogenetic protein: bone morphogenetic protein 7) protein) and human receptor (B) type (B) Btk (Bruton agammaglobulinemia tyrosine kinase: bruton no-gamma-globinopathy tyrosine kinase), BTLA- (B and T lymphocyte associated: B and T lymphocyte related), btn2A2 (butyl philin, subfamily 2, member A2), C1qa (complement component 1,qsubcomponent,alpha polypeptide: complement component 1, q subcomponent, alpha polypeptide), C1QC (complement component 1,q subcomponent,C chain: complement component 1, q subcomponent, C chain), C1R (complement component 1,r subcomponent A: complement component 1, R subcomponent A), C1S (complement component 1,s subcomponent 1: complement component 1, S subcomponent 1), C2cd4A (C2 calcium-dependent domain containing A: C2 calcilc 2-containing domain 4A), C3 (complement component 3: complement component 3), C3ar1 (complement component complement component 3a receptor 1), cab 1 (cell adhesion molecule: cell adhesion molecule 1), CALB1 (calbin 1: calbindin 1), calbin 1: calbindin (calcitonin receptor: calpain) calpain (calpain receptor) calpain)
Capin (cathelicidin antimicrobial peptide: cathepsin 2), CAPN2 (calpain 2: calpain 2), casp1 (Caspase 1: apoptosis protease 1), CASP3 (Caspase 3, apotosis-related cysteine peptidase: apoptosis protease 3, apoptosis-related cysteine peptidase), CAV1 (calpain 1: small socket 1), CBLN2 (calpain 2precursor protein: small brain protein 2precursor protein), CCL1 (C-C ligand 1: chemokine (C-C motif) 1), CCL11 (chemokine (C-C motif) ligand 11), CCL13 (chemokine (C-C motif) ligand 13), CCL15 (C-C motif) ligand 16), CCL1 (C-C motif) ligand 19 (C-C motif) ligand 17), CCL11 (C-C motif) ligand 16 (C-C motif) ligand 17), CCL11 (C-C ligand 17 (C-C motif) ligand 17) CCL2 (C-C motif) ligand 2), CCL20 (C-C motif) ligand 20, CCL21 (C-C motif) ligand 21, CCL22 (C-C motif) ligand 22, CCL23 (C-C motif) ligand 22), CCL23 (C-C motif) ligand 23, CCL24 (C-C motif) ligand 24), CCL25 (C-C motif) ligand 25, CCL4 (C-C ligand 26), CCL4 (C-C motif) ligand 27), CCL4 (C-C ligand 27), CCL24 (C-C motif) ligand 27, CCL24 (C-C motif) ligand 27 CCL5 (chemokine (C-C motif) ligand 5: chemokine (C-C motif) ligand 5), CCL7 (chemokine (C-C motif) ligand 7), CCL8 (chemokine (C-C motif) ligand 8), ccn1 (cellular communication network factor 1: cytokine 1), ccn2 (cellular communication network factor 2: cytokine 2), ccn3 (cellular communication network factor 3: cytokine 3), ccn4 (cellular communication network factor: cytokine 4), ccnd1 (cyclin D1: cyclin D1), ccr1 (chemokine (C-C motif) receptor 1), CCR10 (chemokine (C-C motif) receptor 10), 2 (chemokine (C-C motif) receptor 2), CCR4 (chemokine C4) receptor 2 (chemokine C-C motif), CCR4 (chemokine D1), ccr1 (chemokine C-C motif) receptor 2 (Ccr 4) 2, CCR4 (chemokine D1), CCR10 (chemokine C-C motif) receptor 2 (Ccr 4) 2, CCR4 (chemokine C-C motif) 2, CCR4 (chemokine C-C motif) 2 (CCR 4) CCR5 (chemokine (C-C motif) receptor 5: chemokine (C-C motif) receptor 5), CCR6 (chemokine (C-C motif) receptor 6: chemokine (C-C motif) receptor 6), CCR7 (chemokine (C-C motif) receptor 7: chemokine (C-C motif) receptor 7), CCR8 (chemokine (C-C motif) receptor 8: chemokine (C-C motif) receptor 8), CCR9 (chemokine (C-C motif) receptor 9), ccrl2 (chemokine-like 2: chemokine (C-C motif) receptor-like 2), CD14 (CD 14 antigen), CD151 (CD 151 antigen), CD160 (CD 160 antigen), CD163 (CD 163 antigen), CD164antigen, CD165 antigen, CD180 antigen, CD19 antigen, CD1B antigen, CD22 molecule, CD1D antigen, CD1 molecule, CD2 molecule, CD1 molecule, CD2 molecule, CD1, CD2, CD1 molecule, CD2, CD1, CD2 molecule, CD1, CD2, CD1, CD 9, CD1, CD19, CD180, CD165 antigen, CD165 molecule, CD165 antigen, CD165 molecule, CD1 molecule 2C 2C, C, CD24 (CD 24 molecule), CD244 (CD 244molecule, natural killer cell receptor B4: CD244molecule, natural killer cell receptor 2B 4), CD247 (CD 247 molecule: CD247 molecule), CD248 (CD 248 anti-CD 248 antigen, endosialin), CD27 (CD 27 molecule: CD27 molecule), CD274 (CD 274 anti-CD 274 antigen), CD276 (CD 276 anti-CD 276 antigen), CD28 (CD 28 anti-CD 28 antigen), CD33 (CD 33 anti-CD 33 antigen), CD34 (CD 34 anti-CD 34 antigen), CD36 (CD 36 molecule: CD36 molecule), CD37 (CD 37 molecule: CD37 molecule), CD38 (CD 38 anti-CD 38 antigen), CD3D (CD 3D molecule: CD3D molecule), CD3E (CD 3 anti-CD epsilon polypeptide), CD3G 3 (CD 40 anti-CD 40 antigen), CD34 anti-CD 40 (CD 40 anti-CD 40 antigen), CD34 anti-CD 36 (CD 36 molecule: CD36 molecule), CD37 (CD 37 molecule: CD37 molecule), CD38 (CD 38 anti-CD 38 antigen), CD3D (CD 3D: CD3D molecule), CD3E (CD 3 anti-CD 20 antigen), CD3G 3 (CD 40 anti-CD 40 antigen), CD40 (CD 40 anti-ligand (CD 40 antigen)
CD47 (CD 47 anti (Rh-linked anti, integrin-associated signal transducer): CD47 antigen (Rh-related antigen, integrin-related signal transducer)), CD48 (CD 48 anti: CD48 antigen), CD52 (CD 52 molecule: CD52 molecule), CD53 (CD 53 molecule: CD53 molecule), CD55 (CD 55 molecule: CD55 molecule), CD58 (CD 58 molecule: CD58 molecule), CD59 (CD 59 molecule: CD59 molecule), CD6 (CD 6 molecule: CD6 molecule), CD63 (CD 63 molecule: CD63 molecule), CD68 (CD 68 anti-CD 68 antigen), CD69 (CD 69 molecule: CD69 molecule), CD70 (CD 70 anti-CD 70 antigen), CD74 (CD 74 anti-CD 74 antigen), CD79A (CD 79A molecule, immunoglobulin-related alpha), CD79B (CD 79B molecule, immunoglobulin-related beta), CD80 anti-CD 80, CD83 (CD 83 anti-CD 80 antigen), CD83 (CD 9 anti-CD 86) and CD8 binding protein-alpha, CD 9-alpha, CD79A (CD 9-alpha, CD79A, CD-alpha, CD79A binding protein-alpha, CD79A binding protein, CD 9A binding protein, CD9 binding protein binding and-binding and-binding-and-binding-and- -, CDH5 (Cadherin 5, type 2 (vascular endothelium): cadherin 5, type 2 (vascular endothelial)), CDK4 (cyclin-dependent kinase 4), CDK6 (cyclin-dependent kinase 6: cyclin-dependent kinase 6), CDKN1A (cyclin-dependent kinase inhibitor A (P21): cyclin-dependent kinase inhibitor 1A (P21)), CDKN1B (cyclin-dependent kinase inhibitor B: cyclin-dependent kinase inhibitor 1B), CDKN1C (cyclin-dependent kinase inhibitor C (P57): cyclin-dependent kinase inhibitor 1C (P57)), CDKN2A (cyclin dependent kinase inhibitor A: cyclin-dependent kinase inhibitor 2A), CDKN2B (cyclin dependent kinase inhibitor B: cyclin-dependent kinase inhibitor 2B), CDN 2D (cyclin dependent kinase inhibitor D: cyclin-dependent kinase inhibitor 2D), CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule B) and ACA 3/CEA (ACA-4) and CEA (ACA-5/CEA-5), CEA (ACA-5/CEA (ACA-related cell adhesion molecule (ACA-binding molecule (ACA-2) and CEA-binding molecule (ACA-binding molecule) (4) and CEA-binding molecule (ACM) (4) 3/CEA 6), α), cebpb (CCAAT/enhancer binding protein (C/EBP), beta: CCAAT/enhancer binding protein (C/EBP), β), cebpd (CCAAT/enhancer binding protein (C/EBP), delta: CCAAT/enhancer binding protein (C/EBP), δ), CFD (complement factor D (adipsin): complement factor D (fatty element)), cfh (complement component factor h: complement component factor h), CFI (complement component factor i: complement component factor i), CFL1 (cofilin 1, non-mule: actin 1, non-muscle), CHAD (chondroadherein: cartilage protein), chadl (chondroadherein-like: cartilage-like), CHAT (choline acetyltransferase: choline acetyltransferase), CHEK1 (checkpoint kinase 1: checkpoint kinase 1), chek2 (checkpoint kinase 2: checkpoint kinase 2), CHI3L1 (chirinase 3like 1: chitinase 3-like 1), chrd (chord: crest factor), CHRM2 (cholinergic receptor, mustaryc 2, carpiac: cholinergic receptors, muscarinic 2, heart), chrna7 (cholinergic receptor, nicotinic, alpha polypeptide 7: cholinergic receptor, nicotine, alpha polypeptide 7), CHRNB2 (cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal): cholinergic receptors, nicotine, beta polypeptide 2 (neurons)), chst11 (carbohydrate sulfotransferase 11: carbohydrate sulfotransferase 11), chst4 (carbohydrate sulfotransferase 4: carbohydrate sulfotransferase 4), CIITA (class II transactivator: class II transactivator), clcf1 (cardiotrophin-like cytokine factor 1: cardiomyotrophic protein-like cytokine 1), CLEC11A (Stem cell growth factor: stem cell growth factor), CLSTN2 (calsyntenin 2: calcium syntenin 2),
Clu (clusterin: clusterin), cmklr1 (chemokine-like receptor 1: chemokine-like receptor 1), cnmd (chondromodulin: cartilaginous regulator), CNTF (Ciliary neurotrophic factor: ciliary neurotrophic factor), COL10A1 (collgen, type X, α1), COL11A1 (collgen, type XI, α1: collagen, type XI, α1), COL11A2 (collgen, type XI, α2: collagen, type XI, α2), COL12A1 (collgen, type XII, alpha 1: collagen, type XII, α1), COL14A1 (collgen, type XIV, alpha 1: collagen, type XIV, α1), COL15A1 (collgen, type XV, alpha 1: collagen, type XV, α1), COL16A1 (collgen, type XVI, α1), COL18A1 (collgen, type XVIII, type II, type 1, type α1A1, type IV 1, type IV, type 1, type alpha 1, collagen, type alpha 1 (collage 1) Collagen, type IV, alpha 1) Collagen, type IV, type 1 (collage 1, type IV, alpha 1, collagen, type IV, alpha 1) Collagen, type IV, type, collagen, type IV, type 1 (collage 1, collagen, type IV, type, collagen, type IV, type, collagen, type, and type IV, collagen, type, collagen, type, and type-2, collagen, and type-Collagen, and type-Collagen, and Collagen, and Collagen, collagen, collagen, alpha 6: collagen, type IV, α6), COL5A1 (collagen, type V, alpha 1: collagen, type V, α1), COL6A1 (collagen, type VI, alpha 1: collagen, type VI, α1), COL8A1 (collagen, type VIII, alpha 1: collagen, type VIII, α1), COL9A1 (collagen, type IX, alpha 1: collagen, type IX, α1), COL9A2 (collagen, type IX, alpha 2: collagen, type IX, α2), COL9A3 (collagen, type IX, alpha 3: collagen, type IX, α3), comp (cartilage oligomeric matrix protein: cartilage oligomeric matrix protein), cr2 (complement receptor 2: complement receptor 2), creb1 (cAMP responsive element binding protein 1: cyclic amp response element binding protein 1), CRK (v-CRK avian sarcoma virus CT10 oncogene homolog: v-crk avian sarcoma virus CT10 oncogene homolog), crp (C-reactive protein, pentaxin-related: c-reactive protein, pentameric protein related), crppa (CDP-L-ribitol pyrophosphorylase A: CDP-L ribitol pyrophosphorylase A), cryAB (Crystallin, alpha B: lens protein, αb), CSF1 (colony stimulating factor (macrotage): colony stimulating factor 1 (macrophages)), CSF2 (colony stimulating factor) 2 (granulocyte-map): colony stimulating factor 2 (granulocyte macrophage)), CSF3 (colony stimulating factor 3 (granulocyte): colony stimulating factor 3 (granulocyte)), cst3 (Cystatin C: cystatin C), ctbp1 (C-terminal binding protein 1: c-terminal binding protein 1), ctbp2 (C-terminal binding protein 2: c-terminal binding protein 2), CTLA4 (cytoxic T-lymphocyte-associated protein 4: cytotoxic T lymphocyte-associated protein 4), cnneal 1 (catenin (cadherin associated protein), alpha-like 1: desmin (cadherin-related protein), a-like 1), CTNNB1 (catenin (cadherin associated protein), beta 1: catenin (cadherin-related protein), β1), CTNND1 (catenin (cadherin associated protein), delta 1: chain proteins (cadherin-related proteins), δ1), CTTN (cotact: cortical protein), cx3cl1 (chemokine (C-X3-C motif) ligand 1: chemokine (C-X3-C motif) ligand 1),
Cx3cr1 (C-X3-C motif) receptor 1: chemokine (C-X3-C motif) receptor 1), CXCL1 (C-X-C motif) ligand 1), CXCL10 (C-X-C motif) ligand 10), CXCL11 (C-X-C motif) ligand 11), CXCL12 (C-X-C motif) ligand 11, CXCL13 (C-X-C motif) ligand 12), CXCL13 (C-X-C motif) ligand 10), CXCL11 (C-X-C motif) ligand 11), CXCL12 (C-X-C ligand 12), CXCL13 (C-C ligand 16) ligand 2, CXCL12 (C-X-C motif) ligand 16), CXCL12 (C-X-C motif) ligand 16 (C-X-C motif) ligand 16) CXCL5 (C-X-C motif) ligand 5), CXCL6 (Granulocyte chemotactic protein: granulocyte chemotactic protein), CXCL8 (C-X-C motif chemokine ligand 8:C-X motif) ligand 8, CXCL9 (C-X-C motif) ligand 9, CXCR1 (C-X-C motif) receptor 1, CXCR2 (C-X-C motif) receptor 2: chemokine (C-X-C motif) receptor 2), CXCR3 (C-X-C motif) receptor 3), CXCR4 (C-X-C motif) 1: chemokine (C-X-C motif) receptor 6), CXCR2 (C-X-C motif) receptor 4, CXCR4 (C-C motif) receptor 5, CXCR2 (C-X-C motif) receptor 6, CXCR2 (C-X motif) receptor 6) and CXCR4 (C-X motif) receptor 6, beta polypeptide), cygb (cytoglobin: cytoglobulin), cyp26b1 (cytochrome P450, family 26,subfamily b,polypeptide 1: cytochrome P450, family 26, subfamily b, polypeptide 1), DAPK3 (death-associated protein kinase 3: death-related protein kinase 3), DCN (decorin: decorin), ddit3 (DNA-damage inducible transcript 3: DNA damage-inducing transcript 3), ddr2 (discoidin domain receptor tyrosine kinase 2: disc domain receptor tyrosine kinase 2), DDX58 (DEAD/H box helicase 58: DEAD/H cassette helicase 58), DIAPH1 (diaphanous related formin 1: protein transparent homolog 1), dio2 (deiodinase, iodotyronine, type II: iodothyronine deiodinase II), dkk1 (dickkopf WNT signaling pathway inhibitor 1: dickkopf WNT signaling pathway inhibitor 1), dlk1 (delta like non-canonical Notch ligand 1: delta-like atypical Notch ligand 1), dlx5 (distal-less homeobox 5: homologous transcription factor 5), DLX6 (digital-less homeobox 6: homologous transcription factor 6), DPF1 (D4, zinc and double PHD fingers family 1: d4, zinc and double PHD refer to family 1), DPF3 (D4, zinc and double PHD fingers, family 3: d4, zinc and double PHD refer to, family 3), DPP4 (dipeptidylpiperidine 4: dipeptidyl peptidase 4), dpt (dermotopontin: dermatopontin), DRD2 (dopamine receptor D2: dopamine receptor D2), DSCAM (DS cell adhesion molecule: DS cell adhesion molecule), E2f1 (E2 Ftranscription factor 1: E2F transcription factor 1), EBI3 (Epstein-Barr virus induced gene 3: epstein-barr virus induction gene 3), EDIL3 (EGF-like repeats and discoidin I-like domains 3: EGF-like repeat disc structure I-like domain protein 3), EDN1 (endothelin 1: endothelin 1), ifemp 1 (epidermal growth factor-containing fibulin-like extracellular matrix protein 1: epidermal growth factor-containing fibrin-like extracellular matrix protein 1), EFNB2 (Ephrin-B2: ephrin B2), EGF (epidermal growth factor: epidermal growth factor), egfr (epidermal growth factor receptor: epidermal growth factor receptor), egr2 (early growth response 2: early growth response 2), elane (elastase, neutrophil expressed: elastase, neutrophil expression), elf3 (E74-like factor 3: e74-like factor 3), ENC1 (ectodermal-biological core 1: ectodermal cortex), eng (endoglin: endoglin), enpp3 (ectonucleotide pyrophosphatase/phosphodiesterase 3: outer nucleotide pyrophosphatase/phosphodiesterase 3), ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1: outer nucleoside triphosphate diphosphate hydrolase 1), EP300 (E1A binding protein p300: E1A binding protein p 300), EPAS1 (endothelial PAS domain protein 1: endothelial PAS domain protein 1), epcam (epithelial cell adhesion molecule: epithelial cell adhesion molecule), epha2 (Eph receptor A2: eph receptor A2), ephb2 (Eph receptor B2: eph receptor B2), ephb3 (Eph receptor B3: eph receptor B3), ephx2 (epoxide hydrolase, cytoplasmic: epoxide hydrolase 2, cytoplasm), epo (erythrooietin: erythropoietin), epyc (epihycan: epiphysioproteoglycans), ERBB2 ("V-erb-b 2erythroblastic leukemia viral oncogene homolog, neuro/glioblastoma derived oncogene homolog (avan)": v-erb-b2 erythroleukemia virus oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)), EXT1 (exostosin glycosyltransferase 1: exoosteogenic glycosyltransferase 1), EZR (ezrin: ezrin), F2 (coagulation factor II: coagulation factor II), F2r (coagulation factor II (thrombin) receptor: coagulation factor II (thrombin) receptor), F2rl1 (coagulation factor II (thrombin) receptor-like 1: coagulation factor II (thrombin) receptor like 1), F3 (coagulation factor III), F8 (coagulation factor VIII: factor VIII), fabp4 (fatty acid binding protein, adipoche: fatty acid binding protein 4, adipocytes), FAP (fibroblast activation protein: fibroblast activation protein), FAS (TNF receptor superfamily member 6): fas (TNF receptor superfamily member 6)), fall (Fas ligand (TNF superfamily, member 6): fas ligand (TNF superfamily, member 6)), FASN (fatty acid synthase: fatty acid synthase), fbxo5 (F-box protein 5: f box protein 5), fcer1a (Fc receptor, igE, high afinity I, alpha polypeptide: fc receptor, igE, high affinity I, alpha polypeptide),
FCER1G (Fc receptor, igE, high affinity I, gamma polypeptide: fc receptor, igE, high affinity I, gamma polypeptide), fcgr1a (Fc fragment of IgG receptor Ia: fc fragment of IgG receptor Ia), fcgr3B (Fc fragment of IgG receptor IIIa: fc fragment of IgG receptor IIIa), FGF1 (fibroblast growth factor: fibroblast growth factor 1), FGF10 (fibroblast growth factor: fibroblast growth factor 10), FGF19 (Fibroblast growth factor 19: fibroblast growth factor 19), FGF2 (fibroblast growth factor 2: fibroblast growth factor 2), FGF4 (Fibroblast growth factor 4: fibroblast growth factor 4), FGF6 (Fibroblast growth factor 6: fibroblast growth factor 6), FGF7 (Fibroblast growth factor: fibroblast growth factor 7), FGF9 (Fibroblast growth factor (glia-activating factor): fibroblast growth factor 9 (glial activation factor)), FGFR1 (3996: fibroblast growth factor receptor 1), FGFR2 (fibroblast growth factor receptor 2: fibroblast growth factor receptor 2), FGFR3 (fibroblast growth factor receptor: fibroblast growth factor 3: fibroblast growth factor 4), FGF 3: fm4: fibroblast growth factor 4), FGF9 (Fibroblast growth factor 6: fibroblast growth factor 6), FGF9 (Fibroblast growth factor: fibroblast growth factor 9: fm95), and leucine-like protein-rich in the following receptor (fmt 3: fm3 s 3: f 1) FLT3LG (FMS-like tyrosine kinase 3ligan: FMS-like tyrosine kinase 3 ligand), FMOD (fibromodulin: fibromodulin), FN1 (fibrinectin 1: fibronectin 1), FOXC2 (forkhead box C2: fork box C2), FOXD1 (fork box D1: fork box D1), FOXO1 (fork box O1: fork box O1), FOXO3 (fork box O3), FOXP3 (fork box P3: fork box P3), fpr1 (formyl peptide receptor 1: formyl peptide receptor 1), fpr2 (formyl peptide receptor 2: formyl peptide receptor 2), frizzled-related protein: frizzled related protein, FUT1 (Fucosyl transferase 1 (gamma-L-Fucosyl transferase, H blood group) alpha Fucosyltransferase 1 (galactoside 2-alpha-L-Fucosyltransferase, H blood group)), FUT4 (Fucosyl transferase 4: fucosyltransferase 4), FZD9 (569: F9: formyl peptide receptor 2), GABA 9 (gamma-gamma-gamma, GADD45A (growth arrest and DNA-damage-inducible 45alpha: growth arrest and DNA damage induction 45 alpha), gal (galanin and GMAP prepropeptide: galanin and GMAP pro-peptide), GALNT5 (polypeptide N-acetylgalactosaminyl transferase 5: polypeptide N-acetylgalactosyltransferase 5), GATA2 (GATA binding protein: GATA binding protein 2), GATA3 (GATA binding protein 3: GATA binding protein 3), GATA4 (GATAbinding protein: GATA binding protein 4), GBX2 (gastrulation brain homeobox: gastrulation brain homology box 2), gdf10 (growth differentiation factor 10: growth differentiation factor 10), GDF15 (Growth differentiation factor: growth differentiation factor 15), GDF5 (growth differentiation factor: growth differentiation factor 5), GDF6 (growth differentiation factor: growth differentiation factor 6), GDF7 (Growth differentiation factor: growth differentiation factor 7), GDNF (Glial cell derived neurotrophic factor: glial cell-derived neurotrophic factor), ghsr (growth hormone secretagogue receptor: growth hormone secretagogue), GAB 1 (GLGATA binding protein 3), GL1. Beta. 1-GL1, GL1-GLsinge 1-GLsinge family 1-GLsinge 1-family 1, GLsinge 1-family 1-GLsinge 1-2)
GPC4 (glypican 4: glypican 4), GPI (Glucose-6-phosphate isomerase: glucose-6-phosphate isomerase), gpm B (glycopin m6B: glycoprotein m 6B), gpr17 (G protein-coupled receptor 17: G protein-coupled receptor 17), gpx4 (glutathione peroxidase: glutathione peroxidase 4), grem1 (gremlin 1,DAN family BMP antagonist: glamlin 1, DAN family BMP antagonist), grn (granulin: granule protein), GTF3A (General transcription factor IIIA: universal transcription factor IIIA), GUSB (glucoronidase, beta: glucuronidase, beta), gypa (glycin A: blood group glycoprotein A), GZMB (granzyme B: granule enzyme B), H2ac21 (H2 Aclustered histone: H2A aggregate histone 21), HAPLN1 (hyaluronan and proteoglycan link protein 1: hyaluronic acid and proteoglycan connexin 1), HAS1 (hyaluronan synthase: hyaluronic acid synthase 1), HAT1 (Histone acetyltransferase: histone acetyl transferase 1), hacr 2 (752: type 2: glycoprotein A), hepatitis B (37-5, 4: hepatitis B), h37-37 c, 4 (h37-37, 4), h37-37-h37, 4 (h37-h37, 37-37, 4-h37, and h37-h37, h37-37-h37, h37-37-h37-h3-H- -, hes1 (Hes family bHLH transcription factor: hes family bHLH transcription factor 1), hgf (hepatocyte growth factor: hepatocyte growth factor), hif1a (hypoxia inducible factor, alpha subenit: hypoxia inducible factor 1, alpha subunit), HLA-A (major histocompatibility complex, class I, a: main histocompatibility complex, class I, A), HLA-B (major histocompatibility complex, class I, B: main histocompatibility complex, class I, B), HLA-C (major histocompatibility complex, class I, C: main histocompatibility complex, class I, C), HLA-DMA (major histocompatibility complex, class II, DM alpha: main histocompatibility complex, class II, DM alpha), HLA-DMB (major histocompatibility complex, class II, DM beta: main histocompatibility complex, class II, DM beta), HLA-DOA (major histocompatibility complex, class II, DO alpha: main histocompatibility complex, class II, DO alpha), HLA-DOB (major histocompatibility complex, class II, DO beta: main histocompatibility complex, class II, DO beta), HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1: main histocompatibility complex, class II, DP alpha 1), HLA-DPB1 (major histocompatibility complex, class II, DP 1: main histocompatibility complex, DP 1, DP alpha: main histocompatibility complex, class II, DQ 1, class II-DQ 1, class II-D1, DQ 1, class III, DQ 1, DQ alpha 2: major histocompatibility complex, class II, dqα2), HLA-DQB1 (major histocompatibility complex, class II, DQ beta 1: major histocompatibility complex, class II, dqβ1), HLA-DQB2 (major histocompatibility complex, class II, DQ bete 2: major histocompatibility complex, class II, dqβ2), HLA-DRA1 (major histocompatibility complex, class II, DR alpha: major histocompatibility complex, class II, DR α), HLA-DRB1 (major histocompatibility complex, class II, DR bete 1: major histocompatibility complex, class II, drβ1), HLA-DRB5 (major histocompatibility complex, class II, DR beta 5: major histocompatibility complex, class II, drβ5), HLA-E (major histocompatibility complex, class I, E: major histocompatibility complex, class I, E), HLA-F (major histocompatibility complex, class I, F: major histocompatibility complex, class I, F), HLA-F-AS1 (HLA-F antigen RNA1: HLA-F antisense RNA 1), HLA-G (major histocompatibility complex, class I, G: major histocompatibility complex, class I, G), hmga2 (high mobility group AT-hook 2: high-speed swimming group AT-hook 2), hmox1 (heme oxygenase 1: heme oxygenase 1), HNF1A (HNF 1 homeobox a: HNF1 homology box a), HPSE (Heparanase: heparanase), a,
Hras (Harvey rat sarcoma virus oncogene: hawk rat sarcoma virus oncogene), HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1: hydroxysteroid 11-beta dehydrogenase), HSF1 (heat shock factor 1: heat shock factor 1), HSPA9 (heat shock protein: heat shock protein 9), hspd1 (heat shock protein: chaperonin) heat shock protein (chaperonin)), ibsp (integrin binding sialoprotein: integrin binding sialoprotein), ICAM1 (intercellular adhesion molecule: intercellular adhesion molecule 1), ICAM2 (intercellular cell adhesion molecule: intercellular adhesion molecule), ICAM5 (intercellular adhesion molecule, telecephatin: intercellular adhesion molecule 5, telebrain protein), ICOS (inducible Tcell co-stinger: induced T cell co-stimulatory molecule), ICOSLG (ICOS ligand: ICOS), ID1 (inhibitor of DNA binding 1,HLH protein:DNA binding inhibitor 1, HLH protein), ID2 (inhibitor of DNAbinding: DNA binding inhibitor 2), ID4 (inhibitor of DNAbinding: DNA binding inhibitor 4), IDO1 (inogenamine 2,3-dioxygenase 1: indolamine 2,3-dioxygenase 1), IDO2 (inogenamine 2,3-dioxygenase 2: indolamine 2,3-dioxygenase 2), protein (37-35: 2, 35-interferon-35), IFP-27 (IFP-35, IFP-44, IFP-35 (IFP-35) and IFP-44) IFIH1 (Interferon induced with helicase Cdomain: an Interferon induced by Despirase C domain 1), IFIT1 (Interferon-induced protein with tetratricopeptide repeats 1: an Interferon inducer protein having tetrapeptide repeat 1), IFIT2 (Interferon-induced protein with tetratricopeptide repeats 2: an Interferon inducer protein having tetrapeptide repeat 2), IFIT3 (Interferon-induced protein with tetratricopeptide repeats: an Interferon inducer protein having tetrapeptide repeat 3), IFITM1 (Interferon induced transmembrane protein: an Interferon-induced transmembrane protein 1), IFITM2 (Interferon induced transmembrane protein: an Interferon-induced transmembrane protein 2), IFNA1 (Interferon alpha 1: interferon alpha 1), IFNA17 (Interferon alpha 17), IFNA2 (Interferon, alpha 2: interferon, alpha 2), IFNAR1 (Interferon (alpha and beta). Mu. Receptor 1), IFNB1 (Interferon beta 1, fiber cell), IGF1 (Interferon beta 1, fibroblast), IGF1 (Interferon-alpha 1), insulin factor receptor (IGF 2: insulin factor 1: insulin receptor (IGF 2) gamma-factor 1, insulin receptor (insulin receptor 2) (923-like growth factor 1, insulin receptor 2) (3-35, insulin 2-factor 2), insulin receptor 2 (insulin 2, insulin 2-35, insulin 2-receptor 2) IGFBP1 (insulin-like growth factor binding protein 1: insulin-like growth factor binding protein 1), IGFBP2 (insulin-like growth factor binding protein 2: insulin-like growth factor binding protein 2), IGFBP3 (insulin-like growth factor binding protein: insulin-like growth factor binding protein 3), IGFBP4 (insulin-like growth factor binding protein 4: insulin-like growth factor binding protein 4), IGFBP5 (insulin-like growth factor binding protein: insulin-like growth factor binding protein 5), IGFBP6 (insulin-like growth factor binding protein: insulin-like growth factor binding protein 6), IGFBP7 (insulin-like growth factor binding protein: insulin-like growth factor binding protein 7), igsf11 (immunoglobulin superfamily, membe 11: immunoglobulin superfamily, member 11), ihh (Ind hedgehog: indian ), IL10 (Interleukin 10: interleukin 10), IL10RA (Interleukin 10receptor, alpha: interleukin 10receptor, alpha), IL11 (Interleukin 11: interleukin 11), IL12A (Interleukin 12A: interleukin 12A), IL12B (Interleukin 12B: interleukin 12B) 16), IL12B (Interleukin 17B 12B 16), IL10 (Interleukin 17B 12B 13), IL10 (Interleukin 17B 13), IL10 (Interleukin 10receptor, alpha) IL13 a (Interleukin 10receptor, alpha) and IL 13B 12A (Interleukin 17B 13) IL17C (Interleukin 17C: interleukin 17C), IL17D (Interleukin 17D: interleukin 17D),
IL17F (interlukin 17F: interleukin 17F), IL17ra (Interleukin 17receptor A: interleukin 17receptor a), IL17rb (Interleukin 17receptor B: interleukin 17receptor B), IL17rc (Interleukin 17receptor C: interleukin 17receptor C), IL17re (Interleukin 17receptor E: interleukin 17receptor E), IL18 (Interleukin 18: interleukin 18), IL18r1 (Interleukin 18ep 1: interleukin 18receptor 1), IL18rap (Interleukin 18: interleukin 18receptor 1), IL1a (Interleukin 1alpha: interleukin 1), IL1B (Interleukin 1beta: interleukin 1 beta), IL1F10 (Interleukin 1family,member 10: interleukin 1family, member 10), IL1r1 (Interleukin 1receptor I), IL1r2 (Interleukin 1), IL18rap (Interleukin 21), IL1a (Interleukin 2receptor 23), IL 1alpha: interleukin 23receptor 23, IL 1beta: interleukin 1 alpha), IL1B (Interleukin 1beta: interleukin 1alpha: IL1, IL1 Interleukin 2, IL1 Interleukin 23, IL1B (Interleukin 2receptor 23), IL1B (Interleukin 1beta: interleukin 1 alpha), IL1 Interleukin 2, IL1 Interleukin 23, IL1 Interleukin 2 (Interleukin 2receptor 23), IL1 Interleukin 2 (Interleukin 2, IL1 Interleukin 2receptor 24, IL1 IL2 IL1 IL2 IL2, IL25 (interlukin 25: interleukin 25), IL27 (interlukin 27: interleukin 27), IL2RA (interlukin 2receptor,alpha chain: interleukin 2receptor,. Alpha.chain), IL2RB (Interleukin 2receptor,beta chain: interleukin 2receptor,. Beta.chain), IL2RG (Interleukin 2receptor,gamma chain: interleukin 2receptor,. Gamma.chain), IL3 (Interleukin 3: interleukin 5receptor,. Gamma.), IL31RA (Interleukin 31receptor A), IL6 (Interleukin 6: interleukin 31receptor A), IL34 (Interleukin 34: interleukin 34), IL3RA (Interleukin 3receptor,alpha chain: interleukin 3receptor,. Alpha.chain), IL4 (Interleukin 4: interleukin 4), IL5 (Interleukin 5: interleukin 5 receptor. Alpha.), IL6 (Interleukin 6: interleukin 33), IL 6: IL6R 6: interleukin 7receptor (Interleukin 6: IL7 receptor-. Beta.6: IL 7receptor, IL 6. Gamma.7 receptor, IL 6. IL 6: IL 7receptor, IL 6. Beta.7 receptor, IL 6. IL-6 receptor, IL-6. Beta.6 receptor, IL-6. IL-4. IL-5. IL-6. IL-6. 6 IL6 IL, irak2 (Interleukin-1 receptor-associated kinase: interleukin-1receptor associated kinase 2), IRF1 (interferon regulatory factor: interferon regulator 1), IRF3 (interferon regulatory factor: interferon regulator 3), IRF4 (interferon regulatory factor: interferon regulator 4), IRF7 (interferon regulatory factor 7: interferon regulator 7), IRF9 (interferon regulatory factor: interferon regulator 9), IRS1 (insulin receptor substrate 1: insulin receptor matrix 1), IRS2 (insulin receptor substrate: insulin Interferon receptor matrix 2), ITGA1 (integrin a1: integrin a 1), ITGA10 (integrin, alpha 10: integrin, alpha 10), ITGA11 (integrin alpha 11: integrin alpha 11), ITGA2 (integrin alpha 2: integrin alpha 2), ITGA2b (integrin 2 b) and ITGA2 (integrin alpha 2 b) are described herein as examples
ITGA3 (integrin a3: integrin a 3), ITGA4 (integrin alpha 4: integrin α4), ITGA5 (integrin alpha 5: interferon alpha 5), ITGA6 (integrin alpha 6: integrin alpha 6), ITGA7 (integrin alpha 7: integrin alpha 7), ITGA8 (integrin alpha 8: integrin alpha 8), ITGA9 (integrin alpha 9), ITGAD (integrin, alpha D), ITGAE (integrin alpha E, ephelial-associated: integrin alpha E, epithelial correlation), ITGAL (integrin alpha L), ITGAM (integrin alpha M), ITGAV (integrin alpha V), ITGAX (integrin alpha X), ITGAG 1 (integrin beta 1 (fibronectin beta), GB2 (integrin beta 2), GB3 (integrin beta 3), JAK1 (integrin alpha L), JAGAM (integrin alpha M), ITGAV (integrin alpha V), ITGAX (integrin alpha X), ITGAX 1 (integrin beta), GB2 (integrin beta 2), GB3 (integrin beta 3), JAK1 (integrin alpha B4), japan 1 (integrin beta 7), japan 1 (integrin beta 6), japan 1 (integrin beta 4G 2), japan 1 (integrin beta 6), japan 1 (integrin alpha 8), JAGAV (integrin alpha 1, japan 1 (integrin alpha 2), JAGAM (integrin alpha 3, japan 1 (integrin alpha 2), JAGAM (integrin alpha 3, japan 1 (integrin alpha 2), JAGAP (integrin alpha 3, beta 1 (integrin beta 1), gb (integrin beta 1), GB2 (integrin beta 1 (integrin beta 2), GB2 (integrin beta 2), 3 (integrin 2 b), 3 b (integrin 2 b), 3 b (integrin 2b 3 b, 1 b3 b protein-ligand- -ligand- -, JAK2 (Janus kinase 2: janus kinase 2), jankip 3 (Janus kinase and microtubule interacting protein: janus kinase and microtubule interacting protein 3), JCAD (junctional cadherin associated: cadherin 5 related), JUN (JUN pro-oncogene), KAT2B (K (lysine) acyltransferase 2B: K (lysine) acetyltransferase), kdr (kinase insert domain protein receptor: kinase insertion domain protein receptor), KIF20B (kinesin family member 20B: kinesin family member 20B), KIRREL3 (kirre like nephrin family adhesion molecule 3: krire-like kidney disease protein family adhesion molecule 3), kit (Kit pro-oncogene receptor tyrosine kinase: kit tyrosine kinase), kit like (Kit like) Kit 15 (krf 15: krill like factor 15), KLF2 (krill-like factor 2 (krill) respiratory factor 2 (krill 3) and Kit like factor 3), kit 1 (krill factor 1) and factor 1 (6B), kit 1-factor 1 (678) and factor 1 (6B), kit 1-factor 1 (6726) and factor 1-factor 1 (6) factor 1, factor 1-3 (6) factor 1, factor 1-7B (6) factor 1, factor 1 (7B), factor 1 (6) factor (krill-35 (krill) Kit ligand (Kit) Kit ligand (krill) and kl 15 (krill) KRT1 (Keratin 1: keratin 1), KRT18 (Keratin 18: keratin 18), KRT8 (Keratin 8: keratin 8), L1CAM (L1 cell adhesion molecule: L1 cell adhesion molecule), LAMA1 (lamin, alpha 1: laminin, alpha 1), LAMA2 (lamin, alpha 2: laminin, alpha 2), LAMA3 (lamin, alpha 3: laminin, alpha 3), LAMA4 (lamin, alpha 4: laminin, alpha 4), LAMB1 (lamin B1: laminin B1), lamp1 (lysomal-associated membrane protein 1: lysosomal associated membrane protein 1), lamp2 (lysomal-associated membrane protein: lysosomal associated membrane protein 2), lamtor2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator2: late endosomal/lysosomal adaptor), MAPK and MTOR activator), lbp (lipopolysaccharide binding protein: lipopolysaccharide binding protein), lip (leptin: leptin), lgals1 (lectin, galactose binding, lectin, LILILILILIK 1: 5, LIGALIGAMIN-24), LIGAMIN (LIGAMIN-24), LIGAMIN-5, LIGAMIN-24, LIGAMIN-52, LIGAMIN-24, LIGAMIN-5, LIGAMIN-3, LIGAMIN-5, LINAMIN-5, LIMIN-5, LINAMIN-L and, and, and, LMNB2 (lamin B2: lamin B2), LOX (lysyl oxidase: lysyl oxidase), lpl (lipoprotein lipase: lipoprotein lipase), lrp1 (low density lipoprotein receptor-related protein 1: low density lipoprotein receptor-related protein 1), lrp5 (low density lipoprotein receptor-related protein 5: low density lipoprotein receptor-related protein 5), LRRTM2 (leucine rich repeat transmembrane neuronal 2: leucine-rich repetitive transmembrane neuron 2), LSAMP (limbic system-associated membrane protein: limbic system-related membrane protein), LSM5 (LSM 5 log, U6 small nuclear RNA and mRNAdegradation associated: LSM5 homolog, U6 nuclear microRNA and mRNA degradation-related), lta (lymphotoxin A), ltbp1 (latent transforming growth factor beta binding protein 1: latent transforming growth factor-. Beta. -binding protein 1), ly86 (lymphocyte antigen: lymphocyte antigen 86), ly96 (lymphocyte antigen: lymphocyte antigen 96), lyn (LYN to-only gene, src family tyrosine kinase: LYN pro-gene, src family tyrosine kinase), LYZ (lyme 1: lysozyme 1), FK-protein A (lymphotoxin A), ltbp1 (latent transforming growth factor beta binding protein: latent transforming growth factor-. Beta. -binding protein 1), lyn 86 (39324: lymphocyte antigen 86), lyn 96 (lymphocyte antigen: lymphocyte antigen 62), lyn-96 (lymphokine, LYN-family tyrosine kinase), LYZ (LYZ 1: lysozyme 1), FK-protein A (lymphokine protein A), human oncogene, human tumor protein A (human tumor protein B), human tumor cell B (human tumor cell B), human tumor cell receptor (human tumor cell,
MAGEA10 (melanoma antigen family A,10: melanoma antigen family a, 10), MAGEA12 (MAGE family member A12: MAGE family member a 12), MAGEA3 (melanoma anti, family a,3: melanoma antigen, family A, 3), MAGEA4 (melanoma anti, family A,4: melanoma antigen, family A, 4), MAP2 (microtube-associated protein: microtubule-associated protein 2), MAP2K1 (miggen-activated protein kinase kinase: mitogen-activated protein kinase 1), MAPK1 (miggen-activated protein kinase: mitogen-activated protein kinase 1), MAPK14 (miggen-activated protein kinase: mitogen-activated protein kinase 14), MAPK3 (miggen-activated protein kinase 3: mitogen-activated protein kinase 3), MAPK8 (miggen-activated protein kinase: mitogen-activated protein kinase 8), MAPKAPK2 (MAP-activated protein kinase 2: MAP kinase-activated protein kinase 2), matn1 (matrilin 1,cartilage matrix protein: matriprotein 1, cartilage matrix protein), matn3 (matrilin 3: matriprotein 3), matn4 (matrilin 4: mitogen-activated protein kinase 1), MAPK14 (miggen-activated protein kinase: mitogen-activated protein kinase 14), MAPK3 (migrant-activated protein kinase 8), MAPK3 (miggen-activated protein kinase: mitogen-activated protein kinase 3), MAPK8 (mig-activated protein kinase 8), MAPK-activated protein kinase 2 (MAPK-activated protein kinase 2), MAPK-3 (migrant 37F 3), MEK 2 (Mekine 37, mef37, 37C 2) and Megaskin-37 (37C-35) expressed in human tumor cells, megaskin (37C 2, megaskin 37, factor 37, megase 2, megaskin 37, megasn 2, megasn 37 (37, megascell factor 37, megastumor 37, megascell factor 37 factor-37, megascell factor-protein 37 factor-protein-protein, mgll (monoglyceride lipase: monoglyceride lipase), MICA (MHC class I polypeptide-related sequence A: MHCI class polypeptide related sequence A), MICB (MHC class I polypeptide-related sequence B: MHCI class polypeptide related sequence B), mif (macrophage migration inhibitory factor: macrophage migration inhibitory factor), mir34a (microRNA 34a: microRNA 34 a), MKi67 (antigen identified by monoclonal antibody Ki 67: monoclonal antibody Ki 67-identified antigen), mme (membrane metallo endopeptidase: membrane metalloendopeptidase), MMP1 (matrix metallopeptidase 1: matrix metallopeptidase 1), MMP12 (matrix metallopeptidase: matrix metallopeptidase 12), MMP13 (matrix metallopeptidase 13: matrix metallopeptidase 13), MMP14 (matrix metallopeptidase (membrane-inserted) matrix metallopeptidase 14), MMP15 (matrix metallopeptidase: matrix metallopeptidase 15), MMP16 (matrix metallopeptidase: matrix metallopeptidase 16), MMP2 (matrix metallopeptidase: matrix metallopeptidase 2), MMP25 (matrix metallopeptidase: matrix metallopeptidase 25), MMP3 (matrix metallopeptidase: matrix metallopeptidase 3), MMP7 (797: matrix metallopeptidase 7), MMP3 (37) and Mreel 5-inserted matrix metallopeptidase 14 (inserted membrane), MMP15 (matrix metallopeptidase: matrix metallopeptidase 15), MMP16 (matrix metallopeptidase: matrix metallopeptidase 16), MMP2 (matrix metallopeptidase: matrix metallopeptidase 2), MMP25 (matrix metallopeptidase: matrix metallopeptidase 25), MMP3 (673: matrix metallopeptidase 3), MMP7 (797: MMP 7: matrix metallopeptidase 7), MMP-7 (37) and Mc9 (37-inserted receptor (37) are stimulated by the microRNA (37: 37) MSTN (Myostatin: myostatin), msx1 (msh homeobox 1: msh homeobox 1), msx2 (msh homeobox 2: msh homeobox 2), MX1 (MX dynamin-like GTPase 1: MX dynamin-like GTPase 1), myc (MYC pro-oncogene, bHLH transcription factor: MYC pro-oncogene, bHLH transcription factor), myd88 (myeloid differentiation primary response gene: myeloid differentiation primary gene 88), MYL9 (myosin, light polypeptide, regulation) MYL9 (myosin, 359, regulation) MYL9 (myomin, light polypeptide kinase: myosin, light polypeptide kinase), nampt (nicotinamide phosphoribosyltransferase: nicotinamide ribophosphate transferase), nanog (Nanog homeox: nanog homeobox), NCAM (neural cell adhesion molecule: neural cell adhesion molecule 1), OA2 (nuclear receptor coactivator: nuclear activator 2),
Ncor2 (nuclear receptor co-reflector 2: nuclear receptor co-inhibitor), NCR3LG1 (natural killer cell cytotoxicity receptor 3 ligand 1: natural killer cell receptor 3 ligand 1), NDP (Norrie (pseudo-biological) (human): nori (pseudoglioma) (human)), ndst1 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1: N-deacetylase/N-transsulfonamide (heparosamine) 1), NECTIN2 (NECTIN cell adhesion molecule: connexin cell adhesion molecule 2), NES (Nestin), NETO1 (neuropilin (NRP) and Toloid (TLL) -like 1: neuropilin (NRP) and Toloid (TLL) -like 1), neurogen 1 (neurogenin 1: neurogenin 1), NF1 (neuroface 1: neurofibromaton 1), nfe l1 (nuclear factor, erythroid derived, -like 1: nuclear factor, erythroid derivative 2, like 1), nfe l2 (nuclear factor, erythroid derived, like 2: nuclear factor, erythroid derivative 2, like 1), nf1 (nuclear factor of kappa light polypeptide gene enhancer in B cells, light factor in kappa polypeptide in p 105B 1: light factor, light factor in k 52, light factor in k 62B 1), light factor in k 62, delta: nuclear factor of kappa light polypeptide gene enhancement factor in B cell inhibitor, delta), NGF (Nerve growth factor (beta polypeptide): nerve growth factor (β polypeptide)), NGFR (nerve growth factor receptor (TNFR superfamity, membrane 16): nerve growth factor receptor (TNFR superfamily, member 16)), ninj1 (ninjurin 1: nerve injury induction protein 1), nlrp12 (NLR family, pyrin domain containing 12: NLR family, domain 12 containing sepsis), nlrp3 (NLR family, pyrin domain containing 3: NLR family, domain 3 containing sepsis), NODAL (node homolog (mouse): nodular homolog (mouse)), nog (noggin: cephalexin), NOS1 (nitric oxide synthase 1, incoble: nitric oxide synthase 1, induction), NOS2 (nitric oxide synthase, indable: nitric oxide synthase 2, induction), NOS3 (Nitric oxide synthase (endoprostral cell): nitric oxide synthase 3 (endothelial cells)), NOTCH1 (NOTCH 1), nox4 (NADPH oxidase 4: NADPH oxidase 4), NR0B2 (nuclear receptor subfamily 0,group B,member 2: nuclear receptor subfamily 0, group b, member 2), nr1d1 (nuclear receptor subfamily 1,group D,member 1: nuclear receptor subfamily 1, group d, member 1), NR1H3 (nuclear receptor subfamily 1,group H,member 3: nuclear receptor subfamily 1, h group, member 3), NR3C1 (nuclear receptor subfamily 3,group C,member1: nuclear receptor subfamily 3, group c, member 1), NRF1 (nuclear respiratory factor 1: nuclear respiratory factor 1), NRG1 (neurogulin 1: neuregulin 1), NRGN (neurogin: neurostimulatin), NRP1 (neurophilin 1: neuropilin), NRP2 (Neuropilin 2: neuropilin 2), NT5E (5' nucleotidase, ecto:5' nucleotidase, extracellular), NTF3 (Neurotrophin 3: neurotrophic factor), NTF4 (Neurotrophin 4: neurotrophin 4), NTN4 (netrin 4: axonal guidance factor), ntrk1 (neurotrophic tyrosine kinase, receptor, type 1: neurotrophic tyrosine kinase, receptor, type 1), NUDT6 (Nudix (nucleoside diphosphate linked moiety X) -type motif 6: nudix (nucleoside diphosphate linker X) type motif 6), ogn (osteoproglycin: bone glycine), olr1 (oxidized low density lipoprotein (lectin-like) receptor 1: oxidized low density lipoprotein (lectin-like) receptor 1), orm1 (orosomucoid 1: serotypes mucin 1), orm2 (orosomucoid 2: serotypes mucin 2), osm (oncostatin M: oncostatin M), otor (otoraplin), OXTR (oxytocin receptor: oxytocin receptor), P2rx7 (purinergic receptor P X, ligand-gated ion channel,7: purinergic receptor P2X, ligand-gated ion channel, 7), pak1 (P21 (RAC 1) activated kinase 1: p21 (RAC 1) activated kinase 1), PAK4 (p 21 (RAC 1) activated kinase 4: p21 (RAC 1) activates kinase 4),
PAM (peptidylglycine alpha-amidating monooxygenase: peptidylglycine alpha-amidating monooxygenase), parp4 (poly (ADP-ribose) polymerase family, membrane 4: poly (ADP-ribonucleophile) polymerase family, member 4), PCM1 (pericentriolar material 1: centromere peripheral substance 1), PCNA (proliferating cell nuclear antigen: proliferating cell nuclear antigen), PDCD1 (programmed cell death 1: apoptosis 1), pdcd1lg2 (programmed cell death 1ligand 2: apoptosis 1ligand 2), PDGFA (Platelet derived growth factor, alpha: platelet-derived growth factor, alpha), PDGFb (Platelet derived growth factor, B polypeptide: platelet-derived growth factor, B polypeptide), PDGFRA (Platelet derived growth factor receptor, alpha polypeptide: platelet-derived growth factor receptor, alpha polypeptide), PDGFRB (Platelet derived growth factor receptor, beta polypeptide: platelet-derived growth factor receptor, beta polypeptide), PECAM1 (platel/endothelial cell adhesion molecule 1: platelet/endothelial cell adhesion molecule 1), PENK (preprophapha: pre-brain-peptabein), PF4 (platelf 4: platelet-derived growth factor 4), F (Placental growth factor: platelet-derived growth factor 4), placenta 1: factor X29-homolog protein, P-groove 2, P-groove 4 (phosphopeptide-groove B) and P-groove 2, P-groove 4-groove B-groove (37, P-groove B) are connected, class F), PIGS (Phosphatidylinositol glycan anchor biosynthesis, class S: phosphoinositide-anchored biosynthesis, class S), PIK3CA (phosphotidylinosol-4, 5-biphosphate 3-kinase catalytic subunit alpha: inositol phosphatidate-4, 5-bisphosphate 3-kinase catalytic subunit α), pik3cd (phosphotidylinosotol-4, 5-biphosphate 3-kinase catalytic subunit delta: inositol phosphatidate-4, 5-bisphosphate 3-kinase catalytic subunit delta), pik3cg (phosphotidylinosotol-4, 5-biphosphate 3-kinase catalytic subunit gamma: inositol phosphatidate-4, 5-bisphosphate 3-kinase catalytic subunit gamma), pknox1 (Pbx/knotted 1homeobox: pbx/knot 1 homology box), pla2g2d (phospholipase A2, group IID: phospholipase A2, group IID), pla2g5 (phospholipase A2, group V: phospholipase A2, group V), pla2g7 (phospholipase A2, group VII (platlet-activating factor acetylhydrolase, plasma): phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)), PLAT (plasminogen activator, tissue type: plasminogen activator, tissue type), PLAU (plasminogen activator, urokinase: plasminogen activator, urokinase), PLAUR (plasminogen activator, urokinase receptor: plasminogen activator, urokinase receptor), PLCG1 (phospholipase C, gamma 1: phospholipase C, γ1), PLD1 (phospholipase D1: phospholipase D1), PLG (plasminogen: plasminogen), plin1 (perilipin 1: perilipin 1), pml (PML nuclear body scaffold: PML nucleosome scaffold), POT1 (protection of telomeres a: telomere protection 1A), pou f1 (poudomain, class 4,transcription factor 1: POU domain, class 4, transcription factor 1), POU5F1 (POU class 5homeobox 1: POU class 5homeobox 1), PPARA (peroxisome proliferator activated receptor alpha: peroxisome proliferator activated receptor α), ppard (peroxisome proliferator activator receptor delta: peroxisome proliferator-activated receptor δ), pparg (peroxisome proliferator activated receptor gamma: peroxisome proliferator activated receptor γ), ppargc1a (peroxisome proliferative activated receptor, gamma, coactivator 1alpha: peroxisome proliferator activated receptor, γ, coactivator 1α), PPARGC1B (peroxisome proliferative activated receptor, gamma, coactivator 1beta: peroxisome proliferation-activated receptor, γ, co-activator 1β), ppbp (pro-platelet basic protein: primitive platelet basic protein), prdm16 (PR domain containing: PR domain 16), PRDX4 (peroxiredoxin 4: peroxide reductase 4), PRF1 (performin 1 (pore forming protein): perforin 1 (pore forming protein)), prg4 (proteolycan 4 (megakaryocyte stimulating factor, articular superficial zone protein): proteoglycan 4 (megakaryocyte stimulating factor, joint surface area protein)), prkca (protein kinase C, alpha: protein kinase C, α), prkcd (protein kinase C, delta: protein kinase C, δ), prkcz (protein kinase C, zeta: protein kinase C, ζ), PRL (probactant: prolactin), PROCR (protein C receptor, endothesial: protein C receptor, endothelial), PROK1 (Prokineticin 1: prokineticin 1), PROK2 (Prokineticin 2: prokineticin 2), PROM1 (Prominin 1), pspn (Persefin), ptafr (platelet-activating factor receptor: platelet activating factor receptor),
PTEN (phosphatase and tensin homolog: phosphatase and tensin homologs), PTGES (prostaglandin E synthase: prostaglandin E synthase), ptgfr (prostaglandin Freceptor: prostaglandin F receptor), ptgis (prostagin I2 (prostacyclin) synthases: prostaglandin I2 (cyclin) synthase), ptgs1 (prostagin-endoperoxide synthase 1: prostaglandin endoperoxide synthase 1), ptgs2 (prostagin-endoperoxide synthase 2: prostaglandin endoperoxide synthase 2), pthlh (parathyroid hormone-like peptide: parathyroid hormone-like peptide), ptk2 (PTK 2 protein tyrosine kinase: PTK2 protein tyrosine kinase 2), ptn (pleiotrophin: pleiotrophin), PTPRC (protein tyrosine phosphatase, receptor type, C: protein tyrosine phosphatase, receptor type, C), PTX3 (pentraxin related gene: pentameric protein-related gene), pvr (poliovirus receptor: ridge) myeloblastosis virus receptor), pxn (pacillin: pile protein), pycard (PYD and CARD domain containing: structural domain containing D and CARD), RAB8 (RAB 8: RAB8, RAB 1, RAB 8: RAB 1, RAB 1 (RAB 1, RAC1, RAP-2, RAP-RAYR 1, RAYTAXYTAXX-RAYX-RAKOGX-RAKOW-RAYX-RAKOW-RAW-RAKW-RAJ- -, reg3A (regenerating islet-extended 3 alpha: regenerated islet derived 3 alpha), reg3g (regenerating islet-extended 3gamma: regenerated islet derived 3 gamma), rel (reticuloendotheliosis oncogene: reticuloendotheliosis oncogene), rela (v-Rel reticuloendotheliosis viral oncogene homolog A (avian): v-Rel reticuloendotheliosis virus oncogene homolog A (avian)), retn (resistin: resistance element), RHO (rhodopsin: rhodopsin), rhoa (ras homolog family member A: ras homolog family member A), RHOB (ras homolog family member B: ras homolog family member B), RND3 (Rho family GTPase: RHO family GTPase 3), ROBO1 (roundabout guidance receptor: guide receptor 1), ROBO3 (roundabout guidance receptor: roundabout receptor 3), rock1 (Rho associated coiled-coil containing protein kinase: RHO-related wound coil-containing protein kinase 1), rock2 (Rho associated coiled-coil containing protein kinase: RHO-related wound coil-containing protein kinase 2), RHO (Rco 2: rc-95: 35-95, rc 84), rp 1 (Rp 1: rp 1-35, rp 1-c 1) and Rp 1 (37-3: roundabout receptor 1), rp 1 (37-3: roundabout receptor 1), rp 1 (roundabout guidance receptor: roundabout receptor 3), ro 1 (3: roundabout receptor 1), ro 1: roundabout r2, ro 2 (3929: roundabout receptor 1) RXRA (retinoid X receptor alpha: retinoid X receptor α), S100A8 (S100 calcium binding protein A8 (calgranulin a): S100 calbindin A8 (calgranulin a)), S100A9 (S100 calcium binding protein A (calgranulin B): S100 calbindin A9 (calgranulin B)), S1P3 (Sphingosine-1-phosphate receptor3: sphingosine-1-phosphate receptor 3), S1PR1 (Sphingosine-1-phosphate receptor 1: sphingosine-1-phosphate receptor 1), saa4 (service amyloid A4: serum amyloid A4), scgb1A1 (secretin, family 1A, membrane 1 (secretin), SCN1B (volume channel, volume-gap, type I, beta), SCN3B (volume channel, volume-gap, type III, beta), SDC2 (volume 2: multi-ligand protein 2), SDN 3 (volume channel), SCN1B (volume channel, type I, beta), SCN3B (volume channel, type III, beta), SDC2 (volume 2: multi-ligand protein 2), SCN3 (volume channel), SCN1B (volume channel), type I, beta, SCN3B (volume channel), SCN3B (volume channel, beta), beta) and (volume channel, beta) protein B (volume channel, beta), immunoglobulin domain (Ig), short basic domain, secretion, (semaphorin) 3A), sema7A (Sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A: sema domain, immunoglobulin domain (Ig) and GPI membrane anchor, (semaphorin) 7A), SERPINA1 (serpin family A member 1: serine protease inhibitor family a member 1), SERPINB5 (serpin family B member 5: serine protease inhibitor family B member 5), SERPINC1 (Serpin peptidase inhibitor, clone C (antiphlombin), membrane 1: serine protease inhibitors, branch C (antithrombin), member 1), serpin 1 (serine (or cysteine) peptidase inhibitor, clone E, member 1: serine (or cysteine) peptidase inhibitors, branch E, member 1), SERPINF1 ("Serpin peptidase inhibitor, clone F (alpha-2antiplasmin,pigment epithelium derived factor), membrane 1": "serine protease inhibitor, branched F (alpha-2 antiplasmin, pigment epithelium derived factor) member 1")
Serpin F2 (serine (or cysteine) peptidase inhibitor, clone F, member 2: serine (or cysteine) peptidase inhibitors, branch F, member 2), SERPINH1 (serpin family Hmember 1: serine protease inhibitor family H Member 1), sfrp1 (secreted frizzled-related protein 1: secreted frizzled-related protein 1), SFRP5 (secreted frizzled-related sequence protein: secreted frizzled-related sequence protein 5), SH2B2 (SH 2B adaptor protein: SH2B-adaptor 2), SH3PXD2A (SH 3 and PX domains 2A: SH3 and PX domains 2A), SHB (src activity 2domain-containing transforming protein B: src homolog 2 domain-transforming protein B), SHBG (sex hormone binding globulin: sex hormone binding globulin), SHH (sonic hedgehog) factor, shox2 (short stature homeobox: short homology box 2), sigir (single immunoglobulin and toll-insert kinase 1receptor (receiver) domain: single immunoglobulin and toll-receptor (SIR3: T1), SIR3 (SIR3/SIR3) factor (TIR 1), siR 1 (SLC 3/SiR 6) 5 (45-17) protease enzyme, an acetyl-related protein 1 (SIR2) protein 1, SIR2 (SIR3) protein 1/3 (SIR3) protein 1), an acetyl-related protein 1 (SIRP 1) protein 1, SIRP 2 (3) protein 1) and an acetyl-related protein 1, membrane 3: solute carrier family 1 (glial high affinity glutamate transporter), member 3), slc2a4 (solute carrier family 2 (facilitated glucose transporter), membrane 4: solute carrier family 2 (glucose transporter facilitator) member 4), slc3a2 (solute carrier family 3 (activators of dibasic and neutral amino acid transport), membrane 2: solute carrier family 3 (dibasic and neutral amino acid transport activator) member 2), slc7a5 (solute carrier family membrane 5: solute carrier family 7member 5), SLC9A6 (solute carrier family (sodium/hydrogen exchanger), membrane 6: solute carrier family 9 (sodium/hydrogen exchanger) member 6), SLIT3 (SLIT guidance ligand 3: SLIT index ligand 3), SLIT 6 (SLIT and NTRK-like family, membrane 6: SLIT and NTRK-like family, member 6), SMAD1 (SMAD family member 1: SMAD family member 1), SMAD2 (SMAD family member 2: SMAD family member 2), SMAD3 (SMAD family member 3: SMAD family member 3), SMAD4 (SMAD family member 4: SMAD family member 4), SMAD5 (SMAD family member 5: SMAD family member 5), SMAD6 (SMAD family member 6: SMAD family member 6), SMAD7 (SMAD family member: SMAD family member 7), smurf1 (SMAD specific E3 ubiquitin protein ligase 1: SMAD specific E3 ubiquitin protein ligase 1), SMURF2 (SMAD specific E3 ubiquitin protein ligase 2: SMAD-specific E3 ubiquitin protein ligase 2), SNAI1 (snail family transcriptional repressor 1: snail family transcriptional repressor 1), snai2 (snail family zinc finger 2: snail family zinc finger 2), SNCA (synuclein, alpha: synuclein, α), snx19 (softening nexin 19: sortation-connexin 19), socs3 (suppressor of cytokine signaling 3: cytokine signaling inhibitor 3), socs5 (suppressor of cytokine signaling 5: cytokine signaling inhibitor 5), sod1 (superoxide dismutase, soluble: superoxide dismutase 1, soluble), sort1 (sortilin 1: sortilin 1), st (sclerostin: sclerostin), SOX2 (SRY (sex determining region Y) -box 2: SRY (sex determination region Y) frame 2), SOX4 (SRY (sex determining region Y) -box 4: SRY (sex determination region Y) frame 4), SOX5 (SRY (sex determining region Y) -box 5: SRY (sex determination region Y) frame 5), SOX6 (SRY (sex determining region Y) -box 6: SRY (sex determination region Y) frame 6), SOX9 (SRY (sex determining region Y) -box 9: SRY (sex determination region Y) box 9), SP1 (SP 1transcription factor: sp1transcription factor), sp7 (Sp 7 transcription factor 7: sp7 transcription factor 7), sparc (secreted acidic cysteine rich glycoprotein: secreted acidic cysteine-rich glycoprotein), SPG7 (SPG 7, paraplegin matrix AAA peptidase subunit: SPG7, paraplegic protein matrix AAA, peptidase subunit), SPHK1 (Sphingosine kinase 1: sphingosine kinase 1), spn (sialhophorin: salivary), SPON2 (spondin 2,extracellular matrix protein: crest vertebral protein 2, extracellular matrix protein), spp1 (secreted phosphoprotein 1: secreted phosphoprotein), SPTBN5 (sprucin beta, non-erythrocic 5: ghost β, non-erythrocyte 5), SRC (Rous sarcoma oncogene: rous sarcoma oncogene), srebf1 (sterol regulatory element binding transcription factor 1: cholesterol regulatory modules bind to transcription factor 1), ST3GAL2 (ST 3 beta-galactoside alpha-2,3-sialyltransferase 2: beta-galactoside, alpha-2,3-sialyltransferase 2), ST6GAL1 (beta galactoside alpha 2,6sialyltransferase 1: beta-galactoside alpha-2, 6-sialyltransferase 1),
Stab1 (stabilin 1: statin 1), STAT1 (signal transducer and activator of transcription 1: signal transducer and transcriptional activator 1), STAT3 (signal transducer and activator of transcription 3: signal transducer and transcriptional activator 3), STAT4 (signal transducer and activator of transcription: signal transducer and transcriptional activator 4), STAT5A (signal transducer and activator of transcription A: signal transducer and transcriptional activator 5A), STAT5B (signal transducer and activator of transcription B: signal transducer and transcriptional activator 5B), STAT6 (signal transducer and activator of transcription: signal transducer and transcriptional activator 6), STC1 (stannicalcin 1), STMN3 (stathmin-like 3: microtubule-unstable protein-like 3), HSPA8 (heat shock protein: heat shock protein 8), SVIL (supervillin), syk (spleen tyrosine kinase: spleen tyrosine kinase), SYNGR1 (synaphnogogyrin 1: synaptic circulating protein 1), TAZ (tafazzin), tbx2 (T-box 2:T), TBX21 (T-box 21), tbx3 (T-box 3:T), TBX5 (T-box 5: tbx 3), TEK 5: TEF 2, 5: talbox 2, 5: TEF 2, 5: talbot 2, 5: TEF 2, 5: tbX2, tbX 2: tbX 21: tbX2, tbX 2: tbX2, tbX 2: tbX 2) TERF1 (telomeric repeat binding factor 1: telomere repeat binding factor 1), TERF2 (telomeric repeat binding factor 2: telomere repeat binding factor 2), tert (telomerase reverse transcriptase: telomerase reverse transcriptase), TFAM (transcription factor A, mitochondral: transcription factor A, granulosa), TFRC (transferrin receptor: transferrin receptor), TGFA (Transforming growth factor, alpha: transforming growth factor, alpha), tgfb1 (transforming growth factor, beta 1: transforming growth factor,. Beta.1), tgfb2 (transforming growth factor, beta 2: transforming growth factor,. Beta.2), TGFb3 (transforming growth factor, beta 3: transforming growth factor,. Beta.3), TGFBR1 (transforming growth factor, beta receptor I: transforming growth factor,. Beta.receptor I), TGFBR2 (transforming growth factor, beta receptor II: transforming growth factor,. Beta.receptor II), TGFBR3 (transforming growth factor, beta receptor III: transforming growth factor,. Beta.receptor III), TGIF1 (TGFB induced factor homeobox: inducing factor homology box 1), TGM2 (trans-glaminose 2, C peptide: transglutaminase 2, C polypeptide), thrombin 1 (thrombin: thrombospondin 1,. Beta.3), EGF-37-like protein, EGF 1-37-protein, EGF-2-like protein, and EGF-1-37-like protein, the EGF-1-receptor-containing surface-type antigen-EGF-1, the EGF-receptor-like, the EGF-1-receptor-surface-bound protein-antigen-bound protein-and the protein-bound protein, TIGIT (T cell immunoreceptor with Ig and ITIM domains: T cell immunoreceptor with Ig and ITIM domains), TIMP1 (tissue inhibitor of metalloproteinase: metalloprotease tissue inhibitor 1), TIMP2 (tissue inhibitor of metalloproteinase 2: metalloprotease tissue inhibitor 2), TIMP3 (tissue inhibitor of metalloproteinase 3: metalloprotease tissue inhibitor 3), TIMP4 (tissue inhibitor of metalloproteinase 4: metalloprotease tissue inhibitor 4), tip (toll-interrupt 1receptor (TIR) domain-containing adaptor protein: adaptor protein containing toll interleukin 1receptor (TIR) domain), tlir 1 (toll-like receptor 1), toll-like receptor 1),
Tlr2 (toll-like receptor 2), tlr3 (toll-like receptor 3: toll-like receptor 3), tlr4 (toll-like receptor 4: toll-like receptor 4), tlr5 (toll-like receptor 5: toll-like receptor 5), tlr6 (toll-like receptor 6: toll-like receptor 6), tlr7 (toll-like receptor 7: toll-like receptor 7), tlr8 (toll-like receptor 8: toll-like receptor 8), tlr9 (toll-like receptor 9: toll-like receptor 9), TMEM33 (transmembrane protein: transmembrane protein 33), TMSB15A (thymosin beta 15A: thymosin beta 15A), TNC (tenascin C: tenascin C), tnf (tumor necrosis factor: tumor necrosis factor), tnfapip 3 (tumor necrosis factor, alpha-reduced protein 3: tumor necrosis factor, alpha-induced protein 3), tnfapip 6 (tumor necrosis factor alpha induced protein 6: tumor necrosis factor alpha-induced protein 6), TNFAIP8 (tumor necrosis factor, alpha-reduced protein 8: tumor necrosis factor, alpha-induced protein 8), TNFRSF10C (TNF receptor superfamily member 10C: TNF receptor superfamily member 10C), TNFRSF10D (TNF receptor superfamily member 10C: TNF receptor superfamily member 10C), tnfrsf11b (tumor necrosis factor receptor superfamily, membrane 11b: tumor necrosis factor receptor superfamily member11 b), tnfrsf14 (tumor necrosis factor receptor superfamily, membrane 14 (herpesvirus entry mediator): tumor necrosis factor receptor superfamily 14 (herpes virus invasion medium)) TNFRSF17 (tumor necrosis factor receptor superfamily, member 17: tumor necrosis factor receptor superfamily, member 17), TNFRSF18 (tumor necrosis factor receptor superfamily, member18: tumor necrosis factor receptor superfamily, member 18), TNFRSF1a (tumor necrosis factor receptor superfamily, member1 a), TNFRSF1B (tumor necrosis factor receptor superfamily, member 1B: tumor necrosis factor receptor superfamily, member 1B), TNFRSF4 (tumor necrosis factor receptor superfamily, member 4: tumor necrosis factor receptor superfamily, member 4), TNFRSF9 (tumor necrosis factor receptor superfamily, member 9: tumor necrosis factor receptor superfamily, member 9), TNFRSF10 (tumor necrosis factor (ligand) superfamily, member 10), TNFRSF11 (tumor necrosis factor (ligand) superfamily, member 11), TNFRSF 13 (tumor necrosis factor) superfamily (ligand) superfamily, member 13) and (ligand) superfamily, member 13 (ligand) superfamily) and (member 13) superfamily (ligand) superfamily) are described herein, membrane 18: tumor necrosis factor (ligand) superfamily, member 18), tnfsf4 (tumor necrosis factor (ligand) superfamity, membrane 4: tumor necrosis factor (ligand) superfamily, member 4), tnfsf8 (tumor necrosis factor (ligand) superfamity, membrane 8: tumor necrosis factor (ligand) superfamily, member 8), tnfsf9 (tumor necrosis factor (ligand) superfamity, membrane 9: tumor necrosis factor (ligand) superfamily, member 9), tolip (toll interacting protein: toll interacting protein), TRA (T cell receptor alpha locus: t cell receptor alpha site), traf6 (TNF receptor-associated factor 6: TNF receptor-related factor 6), TRB (T cell receptor beta locus: t cell receptor beta site), trem1 (triggering receptor expressed on myeloid cells 1: trigger receptor 1) expressed on bone marrow cells), trem2 (triggering receptor expressed on myeloid cells 2: trigger receptor 2) expressed on bone marrow cells), TRIM3 (tripartite motif-containing 3: three-motif 3), trp53 (transformation related protein 53: transformation related protein 53), trp53bp1 (transformation related protein 53binding protein 1: transformation-related protein 53binding protein 1), trpv1 (transient receptor potential cation channel, subfamilies V, membrane 1: transient receptor potential cation channel, subfamily V, member 1), tsc2 (TSC complex subunit 2: TSC complex subunit 2),
TSC22D3 (TSC 22 domain family, member 3), tslp (thymic stromal lymphopoietin: thymic matrix lymphopoietin), twist1 (Twist basic helix-loop-helix transcription factor 1: twisted basic helix-loop helix transcription factor 1), twist2 (Twist basic helix-loop-helix transcription factor 2: twisted basic helix-loop helix transcription factor 2), TXNIP (thioredoxin interacting protein: thioredoxin interacting protein), TYMP (3995: thymidine phosphorylase), ucp1 (uncoupling protein 1 (mitochondral, proton carrier): uncoupling protein 1 (granosome, proton carrier)), uts2 (urotensin 2: tail voxel 2), VASH1 (vasohibin 1: vascular inhibitor 1), VASP (vasodi la stimulated phosphoprotein: vascular dilation stimulus phosphoprotein), VCAM1 (vascular cell adhesion molecule 1: vascular cell adhesion molecule 1), vctorcan: 3949: thioredoxin), VEGFR 3 (VEGFR 25), vitamin D (vascular endothelial factor 2: vascular endothelial growth factor (VEGFC 35), vitamin D (35, vascular endothelial growth factor) 35 (vascular endothelial growth factor) 35, vascular endothelial growth factor F3 (vascular endothelial growth factor) and vascular endothelial growth factor (VEGFR 25) VPS13A (vacuolar protein sorting a: tonoplast protein fraction 13A), VPS13C (vacuolar protein sorting 13C: tonoplast protein fraction 13C), vsir (V-set immunoregulatory receptor: V-set immunomodulatory receptor), vtcn1 (V-set domain containing T cell activation inhibitor 1: V-set domain containing T cell activation inhibitor 1), VTN (vitronectin), VWA5A (von Willebrand factor A domain containing A: domain containing von Willebrand factor A5A), VWF (Von Willebrand factor: von Willebrand factor), WEE1 (WEE 1homolog 1 (S.pompe): WEE 1homolog 1 (schizosaccharomyces)), WIPF1 (WAS/WASL interacting protein family, member1: WAS/WASL interacting protein family, member 1), wnt1 (window-type MMTV integration site family, member1: wingless TV integration site family, member 1), wnt10B (window-type MMTV integration site family, member 10B: wingless MMTV integration site family, member 10B), wnt3A (window-type MMTV integration site family, member 3A: wingless MMU 1 family, member 3A), wnt5A (window-24A, member5B, member 54B, member 5-5, member5B, 5-wingless MMU 5, 5B (window 5B), willess 5B (window 5, member 54B, 5, 6, B,.,., xcl (chemokine (C motif) ligand 1: chemokine (C motif) ligand 1), xcr1 (chemokine (C motif) receptor 1: chemokine (C motif) receptor 1), ywhaz (tyrosine 3-monooxygenase/trpopyan 5-monooxygenase activation protein, zeta polypeptide: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activating protein, zeta polypeptide), zfp36 (zinc finger protein: zinc finger 36), ZFP42 (Zinc finger protein homolog (mouse): zinc finger 42homolog (mouse)), zhx3 (zinc fingers and homeoboxes: zinc finger and homeobox 3), zmpste24 (zinc metallopeptidase, STE24: zinc metallopeptidase, STE24), ZNF25 (6225: zinc finger 25), ACTC1 (actin, alpha, cadiac reel 1: actin, alpha, heart 1), AFF3 (AF 4/FMR2 family, membrane 3: AF4/AG2), member (6: F2: 6) and NAK2 (37A 2), NAK2 (37A 1, 37-amino acid, NAK 1), GAN 2 (37A 2), NAK2 (37A 2, 37-10-amino acid, K1) and 4 (37A 1, K1) B3GALT2 (UDP-Gal: betaGlcNAc beta 1, 3-galactose transfferase 2:UDP-Gal. Beta. -GlcNAc-. Beta. -1, 3-galactosyltransferase 2), BST2 (bone marrow stromal cell antigen: bone marrow stromal cell antigen 2), C1orf198 (chromosome 1open reading frame 198: chromosome 1 readable frame 198), C2orf88 (chromosome 2open reading frame 88: chromosome 2 readable frame 88), CCND2 (cyclin D2: cyclin), CEMIP (cell migration inducing protein, hyaluronan binding: cell migration inducing protein, hyaluronic acid binding), CEMIP (nucleic acid receptor) and,
CHAC1 (ChaC glutathione-specific gamma-glutamyl cyclotransferase 1: chaC glutathione-specific gamma-glutamyl cyclotransferase 1), CHRNA1 (cholinergic receptor, icotinic alpha 1: cholinergic receptor, nicotinic α1), CLDN1 (claudin 1: 1) claudin, CLDN11 (claudin 11: claudin 11), CNIH3 (cornichon family AMPA receptor auxiliary protein 3: cornichon family AMPA receptor accessory 3), CNN1 (calponin 1, basic, smooth muscle), CSGALNACT1 (chondroitin sulfate N-acetylgalactosaminiyl transferase 1: chondroitin sulfate N-acetylgalactosyltransferase 1), CTSS (cathepsin S: cathepsin S), CYP1B1 (cytochrome P450, family 1,subfamily B,polypeptide 1: cytochrome P450, family 1, subfamily B, polypeptide 1), DAPK1 (decoath-associated protein kinase 1: death-related protein kinase 1), ddt 4 (DNA damage inducible transcript: dna damage inducing transcript 4), dirac 3 (dirac, GTP-binding RAS-like RAS 3: dirac family, GTP binding RAS 3), f2 (earl 2: f 2: vascular endothelial factor 2), fasciclover (fasciclovir) and fasciclovir 1 (fasciclovir) 1 (fasciclovir 2: vascular endothelial factor 3: vascular endothelial protein P450, family 1), vascular endothelial cell factor (fasciclovir 1) fasciclovir 1 (fasciclovir 2: vascular endothelial factor 3), vascular endothelial cell factor (fasciclovir 1) and vascular endothelial cell factor (fasciclovir 1) vascular endothelial cell factor (fasciclovir 1, fasciclovir (fasciclovir 1), FOSB (FBJ murine osteosarcoma viral oncogene homolog B: FBJ mouse osteosarcoma virus oncogene homolog B), GBP4 (guanylate binding protein: guanylate binding protein 4), GBP5 (guanylate binding protein: guanylate binding protein 5), GFRA1 (GDNF family receptor alpha: GDNF family receptor. Alpha.1), HAS2 (hyaluronan synthase: hyaluronate synthase 2), HHIP (hedgehog interacting protein: a spinup interacting protein), H2AC8 (history cluster 1, H2ae: histone cluster 1, H2 ae), H2AC7 (history cluster 1, H2ad: histone cluster 1, H2 ad), H3C4 (history cluster 1, H3d: histone cluster 1, H3 d), H3C8 (history cluster 1, H3g: histone cluster 1, H3 g), HSP 6 (heat shock protein, HSP-crsytalin-RELAD, B6: heat shock protein, alpha-crystal associated with B6), IL18 (IL 18: human IL-18), KRAP 1-5 (6: human keratin-related protein), KR 1, KRAP 1-6 (6: human peripheral vascular endothelial cell type 1, KRAP-6) is a protein-6 (KRAP-6: 6) which is a human peripheral cell type 1, KRAP-6 (KRAP-6) is a human peripheral cell type 1, KR 1-6, KRAP-6, KR 1-6 is a human peripheral 1, KR 1 is preferred, and is preferred, LMOD1 (leiomodin 1 (smooth muscle): leiomodin1 (smooth muscle)), LRIG3 (leucone-rich repeats and immunoglobulin-like domains 3: leucine-rich repeat and immunoglobulin-like domain 3), LRRC15 (leucine rich repeat containing: leucine-rich repeat 15), LRRC17 (leucine rich repeat containing: leucine-rich repeat 17), LYPD6B (LY 6/PLAUR domain containing B: LY 6/PLAUR-containing domain), MAL (mal, T-cell differentiation protein-like: mal, T-cell differentiation protein-like), MFAP4 (microfibrillar associated protein: microfiber-related protein 4), MKX (mohawk-hole: lmohawak homology cassette), MYC 1 (myctarget 1: myc target), NEFM (neurofan, medium polypeptide: neuronal wire, medium polypeptide), NFASC (neurofan: neuropain), NFATC2 (nuclear factor of activated T-cells, cytoplasmic, calcarea-dependent 2: nuclear factor that activates T-cell cytoplasm, calmodulin-sensitive phosphatase 352), SR1 (OAy 1: membrane-affinity 2), human ligand 1 (membrane-affinity 2), human ligand 1, pH 1-affinity 2 (membrane-affinity 2), human ligand 1 (membrane 2, membrane-affinity 2), human tumor 2 (membrane-mediated 2), human tumor 2 (membrane-associated) and human tumor 2 (human tumor cell receptor) are synthesized PREX1 (phosphotidylinosol-3, 4, 5-triphosphite-dependent Rac exchange factor 1: inositol phosphatidate-3, 4, 5-triphosphate dependent Rac exchange factor 1), PSAT1 (phosphoserine aminotransferase: phosphoserine aminotransferase 1), PSG9 (pregnancy specific beta-1-glycoprotein 9: pregnancy-specific beta-1-glycoprotein 9), RAB27B (RAB 27B, member RAS oncogene family: oncogene member),
RCAN2 (regulator of calcineurin 2: calcineurin modulator 2), RDH5 (retinol dehydrogenase 5 (11-cis/9-cis): retinol dehydrogenase 5 (11-cis/9-cis)), RGCC (regulator of cell cycle: cell cycle modulator), RIMS1 (regulating synaptic membrane exocytosis 1: modulating synaptic membrane exocytosis 1), RORA (RAR-related orphan receptor A: RAR-related nonpathogenic receptor a), RPL12 (Zhang 2013alt_ACCEPTOR, alt_DONOR, coding, INTENAL, intronic best transcript NM _000976:Zhang2013 ALT _receptor, alt_donor, coding, INTENAL, intron optimal transcript NM_ 000976), RSAD2 (radical S-adenosyl methionine domain containing 2: free radical-S-adenosyl-containing methionic acid domain 2), SCRG1 (stimulator of chondrogenesis: chondrogenic stimulator 1), SERPINB2 (serpin peptidase inhibitor, clone B (ovalbumin), memer 2: serine protease inhibitor, branched B (ovalbumin) member 2), SLAMF8 (SLAM family member: slam family member 8), SLC14A1 (solute carrier family) 14 (urea transporter), memb 1 (ki blood group solute transfer) solute domain 2 (radicle-containing 1), SCRG1 (stimulator of chondrogenesis: cartilage production stimulator 1), SERPINB2 (serpin peptidase inhibitor, clone 2: 35, membin 2: 35, member 38), tsuk 2 (sepic factor 1: carrier 38), tsu1 (september 2) THBS4 (thrombi-sensitive protein 4), TINAGL1 (tubulointerstitial nephritis antigen-like 1: renal tubular interstitial nephritis antigen-like 1), TMEM130 (transmembrane protein: transmembrane protein 130), TNMD (tenminosulin: tenascin), UBD (ubigstin D: ubiquitin D), VIT (vitin: vitronectin), XG (Xg blood group; xg pseudogene, Y-linned 2: xg blood group, xg pseudogene, Y-junction 2), GAPDH (glyceraldehyde-3-phosphate dehydrogenase: glyceraldehyde-3-phosphate dehydrogenase), CMRF-56
(2) Removal of specific genes
CMRF-56 in the gene selected in (1) above is removed as a dendritic cell marker. When ordering a Primer to Illumina, inc, 18 genes are removed from the genes that Illumina, inc. The 18 genes are as follows.
HLA-DRB5、NTF4、UTS2、MIF、CD24、CD70、IL17D、C2ORF88、HLA-DQB1、CEMIP、CD165、TRA、TRB、XCL1、ACOD1、CCR10、CXCR3、MIR34A
(3) Preparation of 2 Primer sets
The following 2 primer sets were prepared.
Primer set comprising highly expressed genes
Primer set excluding high-expression Gene
For 38 genes among 1181 genes other than CMRF-56 and the above 18 genes, substitution with another gene was studied for high expression. When the high-expression genes are contained in the primer set, there is a concern that the ratio of these genes in the read count increases, and 2 kinds of primer sets (1143 genes) containing no high-expression genes and primer sets (1181 genes) containing high-expression genes are prepared. The 38 kinds of highly expressed genes were as follows.
ACTB、Ahsg、B2M、Bsg、C3、Calr、CD63、CFL1、Clu、COL6A1
CTNNB1、FASN、FN1、GPC3、GPI、HLA-A、HLA-B、Hspd1、IGFBP3、IGFBP4
IGFBP5、KRT18、KRT8、Lgals1、Mki67、Nfe2l1、SERPINA1、SERPINH1、Slc7a5、Sparc
HSPA8、TFRC、THBS2、TIMP2、TNC、VIM、Ywhaz、GAPDH
Example 8: determination of Gene expression
(1) Reverse transcription
Ampliseq cDNA Synthesis for Illumina (Illumina, 20022654) was used (amplieq cDNA synthesis). AmpliSeq cDNA Reaction Mix (AmpliSeq cDNA reaction mixture), ampliSeq RT Enzymer Mix (AmpliSeq RT enzyme mixture) and prepared mRNA were mixed according to the manufacturer's protocol. This was mounted in a thermal cycler and subjected to an RT reaction. (1 cycle at 42 ℃ C., 30 minutes, followed by 1 cycle at 85 ℃ C., 5 minutes, after which the temperature was maintained at 10 ℃ C., and completed)
(2) PCR reaction (1 st time)
AmpliSeq for Illumina Custom RNAPanel (Illumina, 20020496) and AmpliSeq for Illumina Library PLUS (Illumina, 20019102) were used. The AmpliSeq HiFi Mix, ampliSeq Custom RNAPanel, cDNA were mixed according to the manufacturer's protocol, mounted in a thermocycler and subjected to PCR reactions. (1 cycle at 99 ℃ C., 2 minutes, 15 seconds at 99 ℃ C., followed by 15 cycles at 60 ℃ C., 8 minutes, then maintained at 10 ℃ C., and completed)
(3) Partial digestion of amplified products (Amplicon)
AmpliSeq for Illumina Library PLUS (Illumina, 20019102) was used. After FuPa Reagent was added to the PCR and mixed, the mixture was mounted in a thermal cycler and reacted. ( Each cycle was conducted at 50℃for 10 minutes, at 55℃for 10 minutes, and at 62℃for 20 minutes. Then maintained at 10 ℃ and completed )
(4) Connection of index adapter
AmpliSeq for Illumina Library PLUS (Illumina, 20019102) and AmpliSeq for Illumina CD Indexes Set A (AmpliSeq of Illumina CD index set a) were used (Illumina, 20029105). After the pre-step, switch Solution, ampliSeq CD indexes (AmpliSeq CD index), DNA Ligase (DNA Ligase) were added in rapid succession. After mixing, it was mounted in a thermal cycler and subjected to a ligation reaction. ( Each cycle was performed at 22℃for 30 minutes, at 68℃for 5 minutes, and at 72℃for 5 minutes. Then maintained at 10 ℃ and completed )
(5) Purification
AMPure XP 450mL Kit (BECKMAN COULTER, A63882) was used. After AMPure XP beads were added to the ligation reaction solution and stirred, the mixture was allowed to stand at room temperature for 5 minutes. It was mounted in a magnetic rack, and after standing for 2 minutes, the supernatant was removed. 70% ethanol was added, and after standing for 30 seconds, the supernatant was removed. This was repeated 2 times. Air dried for 10 minutes.
(6) PCR reaction (2 nd time)
AmpliSeq for Illumina Library PLUS was used. Lib Amp Mix, library Amp Primers were mixed, added to the purified sample, and stirred. This was mounted in a thermal cycler and subjected to a PCR reaction, thereby preparing a database. ( 1 cycle was performed at 98℃for 2 minutes, and 7 cycles were performed at 98℃for 15 seconds and at 64℃for 1 minute. Then maintained at 10 ℃ and completed )
(7) Purification
Purification was performed using AMPure XP 450mL Kit. AMPure XP beads were added to the PCR reaction solution and stirred, followed by standing at room temperature for 5 minutes. It was mounted in a magnetic rack, and after standing for 5 minutes, the supernatant was removed. 70% ethanol was added, and after standing for 30 seconds, the supernatant was removed. This was repeated 2 times. It was air-dried for 5 minutes. The mixture was removed from the magnet holder, low TE was added thereto, and the mixture was stirred. It was mounted in a magnetic rack and allowed to stand for 5 minutes. The supernatant was recovered and set as NGS database.
(8) Quantification of
KAPA Library Quantification Kit (KAPA BIOSYSTEMS) was used. The NGS database was concentration adjusted and mixed with KAPAMaster Mix. Standard was also mixed with KAPA Master Mix as well. qPCR was performed using CFX96 Real-Time System (CFX 96 instant presentation System) and quantified.
(9) Sequence(s)
PhiX Control kit v3 (Illumina TG-110-3001) was used. The database was diluted and 0.2N NaOH solution was added to modify it to ssDNA. HT1 was added thereto. PhiX control DNA was similarly modified. These were added to kits of the kit and sequenced using MiSeq (Illumina).
Example 9: data processing of Gene expression
The lead data was imported into QIAGEN company CLC Genomics Workbench. The sequence information to be referred to at the time of the introduction was Homo sapience sequence. The lead data has a value of probability of error for each base. If the lead data is imported into CLC Genomics Workbench, it is converted into a wired Score. The Phred Score was scored as Log of the probability of base errors multiplied by-10 (equation).
Phred Score＝-10×log 10 P err
Quality trimming was performed using a Phred Score. The order of quality trimming is shown below. First, the Phred Score is converted to a p value (formula).
P err ＝10 -phredScore/10
Next, the difference between Limit (0.05) and p value set at the time of trimming was calculated, and the cumulative sum of the differences was calculated. At this time, the value of 0 or less is set to 0. The post-trimming lead start point is set to a point where the cumulative sum becomes 0 or more for the first time, and the post-trimming lead end point is set to a point where the cumulative sum becomes maximum.
After the quality trimming, the number of leads was converted into an expression amount in the following order. First, the lead sequence is aligned to the most similar region on the genome. Next, RPKM (Read Per Kilobase Million: readings per kilobase per million total readings) was calculated using the following formula.
RPKM = number of leads mapped to exon region +.a [ number of all leads mapped to its sample (megaunit) ×length of exon (kb) ]
The value obtained by dividing RPKM by the sum of RPKM is calculated as TPM (Transcript Per Million: per million specifications).
In the case of performing logarithmic processing on TPM, the defect value was processed by the expression of "read count of each gene + (1 Xgene length/average of gene length:1 Xgene length/average value of gene lens)", and then RPKM and TPM were calculated.
Further, regarding the processing of the defect value, even in the case of using the detected minimum value or the case of inserting the detection lower limit value, the same analysis result can be obtained.
Example 10: analysis of Gene expression data
The correlation coefficient and the determination coefficient based on the measured genome are calculated using the value obtained by performing logarithmic processing on the TPM value of each gene expression data. The correlation coefficient was calculated using the CORREL function used in Microsoft Excel (registered trademark) described in the present specification, and the determination coefficient was calculated using the RSQ function used in Microsoft Excel (registered trademark) described in the present specification. The central value of the synovial MSC group, the central value of the L-bone marrow MSC group, and the central value of the REC-MSC group, each of which uses the central value of each cell group, were also calculated. The values of the determined coefficients are shown in Table 3 below in comparison with the cell values of 1 Lot.
TABLE 3
As a result, for each MSC, a boundary value with another MSC group and a boundary value with a non-MSC group can be set at the time of quality control.
It is known that another group of synovial MSCs, which are synovial MSCs, have a determinant coefficient of 0.886 in the case of synovial MSCs, and 0.949 in the case of the central value of the synovial MSC population. It is also known that when comparing MSCs with MSCs derived from other organizations, the number of MSCs is 0.821, 0.786, 0.821, 0.663, and when a synovial MSC is defined in the MSC group, the management can be performed by using a decision coefficient of 0.83 or more as a threshold. It is also known that a determination coefficient of about 0.093 to 0.720 in comparison with the non-MSC cell type can be set to about 0.75 as threshold management of MSC derived from living tissue.
It was also found that another synovial MSC, which is a bone marrow MSC, had a coefficient of 0.916 if it was L bone marrow MSCs, and 0.961 if it was the central value of the bone marrow MSC population. It is also known that when the number of MSCs is 0.864, 0.873, 0.833, and 0.755 in comparison with MSCs derived from other organizations, and bone marrow MSCs are defined in the MSC group, management can be performed by using a decision coefficient of 0.88 or more as a threshold. It is also known that a determination coefficient of about 0.111 to 0.773 in comparison with non-MSC cell types can be set to about 0.78 as threshold management of MSCs derived from living tissues.
It was also found that another synovial MSC, which is a fat MSC, had a coefficient of 0.905 for L fat MSCs and 0.960 for the central value of the fat MSC population. It is also known that when the number of MSCs is 0.841, 0.823, 0.826, and 0.711 in comparison with MSCs derived from other organizations, and bone marrow MSCs are defined in the MSC group, management can be performed by using a decision coefficient of 0.85 or more as a threshold. It is also known that a determination coefficient of about 0.113 to 0.746 in comparison with non-MSC cell types can be set to about 0.75 as threshold management of living tissue-derived MSCs.
In addition, it is also known that iPSC-MSCs have a low coefficient of determination in MSC cell types and have properties different from those of MSCs derived from living tissues (to an extent indistinguishable from FB (fibroblasts)). This is considered to be a very reasonable result if iPSC-MSC is a cell artificially produced by a special differentiation induction and the production process is significantly different.
In view of the results of measurement of the genes having high expression and the effects on quality control thereafter, it was found that the preparation of the primer set (1143 genes) containing no genes having high expression and the primer set (1181 genes) containing genes having high expression was performed, but as a result, the same primer set could be used without any difference. From these results, it was found that the step of managing the patterns of a plurality of gene expression sets specific to cells is very useful in the quality control of the cells from the viewpoints of proving the equivalence and the homogeneity.
Example 11: all gene expression analysis
An analysis of Human Transcriptome Sequencing (human transcriptome sequencing) was performed on mRNA samples of each cell prepared in example 6 using RIKEN GENESIS co. After sequence analysis of the subjects was performed by NovaSeq6000 (Illumina, 20012850), the lead data was analyzed using DRAGEN ver.3.7.5, thereby calculating the gene expression levels of all genes (25,192) as the TPM. The gene names of all genes (25,192) are set forth at the end of this example.
The same analysis as in example 10 was performed with respect to the above combinations of all 25,192 gene expressions and 1,143 genes randomly extracted from all 25,192 gene expressions. In addition, in order to compare the usefulness of the gene set in quality control of cells, a detection force was calculated.
First, a coefficient of variation of the central value of each cell with respect to the target cell population in each gene set is calculated. Then, the detection force is calculated according to the following equation.
Detection force (selection 1143 for random 1143) = { "coefficient of variation of 1143 gene expression of primer set excluding high-expression genes selected in example 7 } +{" coefficient of variation of random 1143 gene expression randomly extracted in example 11 })
Detection force (screening 1143 for a total of 25192) = { "coefficient of variation of 1143 gene expression of primer set excluding highly expressed genes screened in example 7 } +{" coefficient of variation of a total of 25192 gene expression obtained in example 11 })
Table 4, table 5 and table 6 are summarized together with the coefficient of variation obtained as described above and the coefficient of determination obtained in the same manner as in example 10.
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As a result, it was found that, for each MSC, the boundary value with another MSC population and the boundary value with a non-MSC population at the time of quality control could be set, regardless of whether all 25,192 gene sets or 1,143 gene sets extracted at random were used.
For example, it was found that another group of synovial MSCs, which were synovial MSCs, had a determinant coefficient of 0.950 in random 1,143 genes, 0.947 in all 25,192 genes, 0.978 in random 1,143 genes, and 0.978 in all 25,192 genes, for the central value of the synovial MSC population. It was found that, when comparing MSCs derived from other tissues, 0.950, 0.910, 0.921 in random 1,143 genes, 0.928, 0.912, and 0.919 in all 25,192 genes, and when defining synovial MSCs in the MSC population, it was possible to manage the MSCs by using, as a threshold, a determination coefficient of 0.96 or more in random 1,143 genes and 0.93 or more in all 25,192 genes. It is also known that, in comparison with the non-MSC cell types, the determination coefficients are about 0.541 to 0.896 in the random 1,143 genes and about 0.592 to 0.886 in all 25,192 genes, and the threshold management of MSCs derived from living tissues can be set to about 0.90 in the random 1,143 genes and about 0.90 in all 25,192 genes. It is known that threshold management can be similarly performed in L bone marrow MSCs or L fat MSCs.
On the other hand, it was found that when the detection forces were compared, the 1,143 gene sets selected in example 7 showed 2.07 to 2.99 times higher detection forces than the case where all 25,192 genes were used, and also showed 1.90 to 4.67 times higher detection forces than the case where random 1,143 genes were used, and were gene sets capable of showing differences from various cells with high detection forces.
In fact, it was found that the coefficient of determination for each cell type was significantly lower than that in the case where the random 1,143 gene sets or all 25,192 gene sets were used, and therefore, the gene set was excellent as a gene set for quality control in that cell type. Therefore, it was found that quality control of the present invention can be achieved by using all gene sets or randomly extracted gene sets, and it was confirmed that quality control with higher accuracy can be achieved by screening more sensitive gene sets.
DDX11L1、WASH7P、MIR1302-2、FAM138A、OR4F5、LOC729737、LOC100996522、LOC100132287、LOC100288646、OR4F29、OR4F16、LOC100133331、LOC100288069、LOC100287934、FAM87B、LINC00115、LOC643837、FAM41C、LOC284600、LOC100130417、SAMD11、NOC2L、KLHL17、PLEKHN1、C1orf170、HES4、ISG15、AGRN、RNF223、C1orf159、LOC254099、MIR200B、MIR200A、MIR429、TTLL10、TNFRSF18、TNFRSF4、SDF4、B3GALT6、FAM132A、UBE2J2、SCNN1D、ACAP3、PUSL1、CPSF3L、GLTPD1、TAS1R3、DVL1、MXRA8、AURKAIP1、CCNL2、LOC148413、MRPL20、ANKRD65、TMEM88B、VWA1、ATAD3C、ATAD3B、ATAD3A、TMEM240、SSU72、C1orf233、MIB2、MMP23B、CDK11B、SLC35E2B、MMP23A、CDK11A、SLC35E2、NADK、GNB1、CALML6、TMEM52、C1orf222、KIAA1751、GABRD、PRKCZ、C1orf86、SKI、MORN1、LOC100129534、RER1、PEX10、PLCH2、PANK4、HES5、LOC115110、LOC100133445、TNFRSF14、LOC100996583、FAM213B、MMEL1、TTC34、ACTRT2、FLJ42875、LOC100996587、PRDM16、MIR4251、ARHGEF16、MEGF6、MIR551A、TPRG1L、WRAP73、TP73、TP73-AS1、CCDC27、SMIM1、LRRC47、CEP104、DFFB、C1orf174、LOC100133612、LOC728716、LOC284661、AJAP1、MIR4417、MIR4689、NPHP4、KCNAB2、CHD5、RPL22、RNF207、ICMT、LINC00337、HES3、GPR153、ACOT7、LOC100130071、HES2、ESPN、MIR4252、TNFRSF25、PLEKHG5、NOL9、TAS1R1、ZBTB48、KLHL21、PHF13、THAP3、DNAJC11、LOC100505887、LOC100996592、CAMTA1、LOC100129476、VAMP3、PER3、UTS2、TNFRSF9、PARK7、ERRFI1、SLC45A1、RERE、ENO1、ENO1-AS1、CA6、SLC2A7、SLC2A5、GPR157、MIR34A、H6PD、SPSB1、LOC100506022、SLC25A33、TMEM201、PIK3CD、C1orf200、CLSTN1、FLJ16126、CTNNBIP1、LZIC、NMNAT1、MIR5697、RBP7、UBE4B、KIF1B、MIR1273D、PGD、APITD1-CORT、APITD1、CORT、DFFA、PEX14、CASZ1、C1orf127、TARDBP、MASP2、SRM、EXOSC10、MTOR、MTOR-AS1、ANGPTL7、UBIAD1、PTCHD2、FBXO2、FBXO44、FBXO6、MAD2L2、DRAXIN、LOC100996614、AGTRAP、C1orf167、LOC100506310、MTHFR、CLCN6、NPPA-AS1、NPPA、NPPB、RNU5E-1、KIAA2013、PLOD1、MFN2、MIIP、TNFRSF8、TNFRSF1B、MIR4632、VPS13D、SNORA59A、DHRS3、AADACL4、AADACL3、C1orf158、PRAMEF12、PRAMEF1、PRAMEF11、HNRNPCL1、PRAMEF2、PRAMEF4、PRAMEF10、PRAMEF7、PRAMEF6、PRAMEF22、PRAMEF23、PRAMEF25、LOC440563、LOC645359、PRAMEF3、PRAMEF5、PRAMEF8、PRAMEF9、PRAMEF13、PRAMEF18、PRAMEF16、PRAMEF21、PRAMEF15、PRAMEF14、PRAMEF19、PRAMEF17、PRAMEF20、LRRC38、PDPN、PRDM2、KAZN、C1orf126、TMEM51、FHAD1、EFHD2、CTRC、CELA2A、CELA2B、CASP9、DNAJC16、AGMAT、DDI2、RSC1A1、PLEKHM2、SLC25A34、TMEM82、FBLIM1、UQCRHL、FLJ37453、SPEN、ZBTB17、
C1orf64、HSPB7、CLCNKA、CLCNKB、FAM131C、EPHA2、ARHGEF19、RSG1、FBXO42、SZRD1、SPATA21、NECAP2、CROCCP3、RNU1-1、LOC100506533、LOC100133301、NBPF1、CROCCP2、MST1P2、RNU1-3、LOC729574、ESPNP、LOC729587、RNU1-4、MST1L、MIR3675、RNU1-2、CROCC、MFAP2、ATP13A2、SDHB、PADI2、LOC400743、PADI1、PADI3、MIR3972、PADI4、PADI6、RCC2、ARHGEF10L、ACTL8、IGSF21、KLHDC7A、PAX7、TAS1R2、ALDH4A1、MIR4695、MIR1290、IFFO2、UBR4、EMC1、MRTO4、AKR7L、AKR7A3、LOC100506730、AKR7A2、PQLC2、CAPZB、LOC644083、MINOS1、C1orf151-NBL1、NBL1、HTR6、TMCO4、RNF186、OTUD3、PLA2G2E、PLA2G2A、PLA2G5、PLA2G2D、PLA2G2F、PLA2G2C、UBXN10、VWA5B1、LOC339505、CAMK2N1、MUL1、FAM43B、CDA、PINK1、DDOST、KIF17、SH2D5、HP1BP3、EIF4G3、MIR1256、ECE1、LOC100506801、NBPF3、ALPL、RAP1GAP、USP48、LDLRAD2、HSPG2、CELA3B、CELA3A、LINC00339、CDC42、WNT4、MIR4418、ZBTB40、EPHA8、C1QA、C1QC、C1QB、EPHB2、MIR4684、MIR4253、LACTBL1、LOC729059、KDM1A、MIR3115、MIR4419A、LUZP1、HTR1D、LOC100996511、HNRNPR、ZNF436、C1orf213、TCEA3、ASAP3、E2F2、ID3、MDS2、RPL11、TCEB3、LOC100506963、PITHD1、LYPLA2、GALE、HMGCL、FUCA1、CNR2、MIR378F、PNRC2、SRSF10、MYOM3、IL22RA1、IL28RA、LOC284632、GRHL3、STPG1、NIPAL3、RCAN3AS、RCAN3、NCMAP、SRRM1、CLIC4、RUNX3、MIR4425、SYF2、C1orf63、RHD、TMEM50A、RHCE、TMEM57、LDLRAP1、MAN1C1、SEPN1、FAM54B、LOC646471、AUNIP、PAQR7、STMN1、MIR3917、PAFAH2、EXTL1、SLC30A2、TRIM63、PDIK1L、FAM110D、ZNF593、CNKSR1、CATSPER4、CEP85、SH3BGRL3、UBXN11、CD52、AIM1L、ZNF683、LIN28A、DHDDS、HMGN2、RPS6KA1、MIR1976、ARID1A、PIGV、ZDHHC18、SFN、GPN2、GPATCH3、NR0B2、NUDC、C1orf172、OSTCP2、TRNP1、FAM46B、SLC9A1、WDTC1、TMEM222、LOC644961、RNU6-48、SYTL1、MAP3K6、FCN3、CD164L2、GPR3、WASF2、AHDC1、FGR、IFI6、FAM76A、STX12、PPP1R8、SCARNA1、THEMIS2、RPA2、SMPDL3B、XKR8、EYA3、PTAFR、DNAJC8、ATPIF1、SESN2、MED18、PHACTR4、RCC1、SNHG3、SNORA73A、RNU105A、TRNAU1AP、SNHG12、SNORD99、SNORA61、SNORA44、SNORA16A、RAB42、TAF12、RNU11、GMEB1、YTHDF2、OPRD1、EPB41、TMEM200B、SRSF4、MECR、PTPRU、MATN1、MATN1-AS1、LAPTM5、MIR4420、SDC3、PUM1、SNORD103A、SNORD103B、SNORD85、NKAIN1、SNRNP40、ZCCHC17、FABP3、SERINC2、LOC149086、LOC284551、TINAGL1、HCRTR1、PEF1、COL16A1、BAI2、MIR4254、SPOCD1、PTP4A2、KHDRBS1、TMEM39B、MIR5585、KPNA6、TXLNA、CCDC28B、IQCC、DCDC2B、TMEM234、EIF3I、MTMR9LP、FAM167B、LCK、HDAC1、MARCKSL1、LOC100128071、TSSK3、BSDC1、ZBTB8B、ZBTB8A、ZBTB8OS、RBBP4、SYNC、KIAA1522、YARS、S100PBP、FNDC5、HPCA、TMEM54、RNF19B、AK2、ADC、TRIM62、
ZNF362、PHC2、MIR3605、ZSCAN20、CSMD2、HMGB4、LOC402779、C1orf94、MIR552、GJB5、GJB4、GJB3、GJA4、C1orf212、DLGAP3、LOC653160、ZMYM6NB、ZMYM6、ZMYM1、LOC100996496、SFPQ、ZMYM4、KIAA0319L、NCDN、TFAP2E、PSMB2、C1orf216、CLSPN、EIF2C4、EIF2C1、EIF2C3、TEKT2、ADPRHL2、COL8A2、TRAPPC3、MAP7D1、THRAP3、SH3D21、EVA1B、LOC100127947、STK40、LSM10、OSCP1、MRPS15、CSF3R、GRIK3、MIR4255、LOC728431、ZC3H12A、MEAF6、MIR5581、SNIP1、DNALI1、GNL2、RSPO1、C1orf109、CDCA8、EPHA10、MANEAL、YRDC、C1orf122、MTF1、INPP5B、SF3A3、FHL3、UTP11L、POU3F1、MIR3659、LOC339442、RRAGC、GJA9-MYCBP、MYCBP、GJA9、RHBDL2、AKIRIN1、NDUFS5、MACF1、KIAA0754、BMP8A、PPIEL、PABPC4、SNORA55、HEYL、NT5C1A、HPCAL4、PPIE、BMP8B、OXCT2、TRIT1、MYCL1、MFSD2A、CAP1、PPT1、RLF、TMCO2、ZMPSTE24、COL9A2、SMAP2、ZNF643、ZNF642、EXO5、ZNF684、RIMS3、LOC100130557、NFYC、MIR30E、MIR30C1、KCNQ4、CITED4、CTPS1、SLFNL1-AS1、SLFNL1、SCMH1、FOXO6、EDN2、HIVEP3、GUCA2B、GUCA2A、FOXJ3、RIMKLA、ZMYND12、PPCS、CCDC30、PPIH、YBX1、CLDN19、LEPRE1、C1orf50、LOC100129924、CCDC23、ERMAP、ZNF691、SLC2A1、SLC2A1-AS1、FAM183A、EBNA1BP2、WDR65、TMEM125、C1orf210、TIE1、MPL、CDC20、ELOVL1、MED8、SZT2、HYI、PTPRF、KDM4A、KDM4A-AS1、ST3GAL3、ARTN、IPO13、DPH2、ATP6V0B、B4GALT2、CCDC24、SLC6A9、KLF17、DMAP1、ERI3、RNF220、MIR5584、TMEM53、C1orf228、RNU5F-1、RNU5D-1、KIF2C、RPS8、SNORD55、SNORD46、SNORD38A、SNORD38B、BEST4、PLK3、TCTEX1D4、BTBD19、PTCH2、EIF2B3、HECTD3、UROD、ZSWIM5、LOC400752、HPDL、MUTYH、TOE1、TESK2、CCDC163P、MMACHC、PRDX1、AKR1A1、NASP、CCDC17、GPBP1L1、RPS15AP10、TMEM69、IPP、MAST2、PIK3R3、TSPAN1、POMGNT1、LURAP1、RAD54L、LRRC41、UQCRH、NSUN4、FAAH、LOC729041、DMBX1、MKNK1-AS1、KNCN、MKNK1、MOB3C、ATPAF1、TEX38、KIAA0494-AS1、KIAA0494、CYP4B1、CYP4Z2P、CYP4A11、CYP4X1、CYP4Z1、CYP4A22、PDZK1IP1-AS1、PDZK1IP1、TAL1、STIL、CMPK1、FOXE3、FOXD2-AS1、FOXD2、TRABD2B、SKINTL、SLC5A9、SPATA6、AGBL4、BEND5、ELAVL4、DMRTA2、FAF1、CDKN2C、MIR4421、C1orf185、RNF11、TTC39A、EPS15、OSBPL9、NRD1、MIR761、RAB3B、TXNDC12、KTI12、BTF3L4、ZFYVE9、CC2D1B、ORC1、PRPF38A、ZCCHC11、GPX7、FAM159A、SELRC1、ZYG11B、ZYG11A、ECHDC2、SCP2、MIR1273F、MIR5095、MIR1273G、PODN、SLC1A7、CPT2、C1orf123、MAGOH、LOC100507564、LRP8、SLC25A3P1、DMRTB1、GLIS1、TMEM48、YIPF1、DIO1、HSPB11、LRRC42、LDLRAD1、TMEM59、TCEANC2、MIR4781、CDCP2、CYB5RL、MRPL37、SSBP3、C1orf191、ACOT11、FAM151A、HEATR8、HEATR8-TTC4、TTC4、PARS2、TTC22、C1orf177、DHCR24、TMEM61、BSND、PCSK9、USP24、
LOC100507634、MIR4422、LOC100507652、PPAP2B、PRKAA2、C1orf168、C8A、C8B、DAB1、OMA1、TACSTD2、MYSM1、JUN、LOC100131060、HSD52、FGGY、MIR4711、HOOK1、CYP2J2、C1orf87、LOC100996570、NFIA、TM2D1、INADL、MIR3116-1、MIR3116-2、L1TD1、KANK4、USP1、DOCK7、ANGPTL3、LOC100507664、LOC400756、ATG4C、LINC00466、LOC100996301、FOXD3、ALG6、ITGB3BP、EFCAB7、DLEU2L、PGM1、ROR1、UBE2U、CACHD1、MIR4794、RAVER2、JAK1、MIR3671、MIR101-1、AK4、DNAJC6、LEPROT、LEPR、PDE4B、SGIP1、MIR3117、TCTEX1D1、INSL5、WDR78、MIER1、SLC35D1、C1orf141、IL23R、IL12RB2、SERBP1、GADD45A、GNG12、GNG12-AS1、DIRAS3、WLS、MIR1262、RPE65、DEPDC1、LRRC7、PIN1P1、LRRC40、SRSF11、ANKRD13C、HHLA3、CTH、PTGER3、ZRANB2-AS1、ZRANB2、MIR186、ZRANB2-AS2、NEGR1、NEGR1-IT1、LRRIQ3、FPGT-TNNI3K、FPGT、TNNI3K、C1orf173、CRYZ、TYW3、LHX8、SLC44A5、ACADM、RABGGTB、SNORD45C、SNORD45A、SNORD45B、MSH4、ASB17、ST6GALNAC3、ST6GALNAC5、PIGK、AK5、ZZZ3、USP33、FAM73A、NEXN-AS1、NEXN、FUBP1、DNAJB4、GIPC2、MGC27382、PTGFR、IFI44L、IFI44、ELTD1、LPHN2、TTLL7、PRKACB、SAMD13、UOX、DNASE2B、RPF1、GNG5、SPATA1、CTBS、C1orf180、SSX2IP、LPAR3、MCOLN2、MCOLN3、WDR63、MIR4423、SYDE2、C1orf52、BCL10、LOC646626、DDAH1、CYR61、ZNHIT6、COL24A1、ODF2L、CLCA2、CLCA1、CLCA4、CLCA3P、SH3GLB1、SEP15、HS2ST1、LOC339524、LMO4、LOC100505768、PKN2、GTF2B、CCBL2、RBMXL1、GBP3、GBP1、GBP2、GBP7、GBP4、GBP5、GBP6、GBP1P1、LRRC8B、FLJ27354、LRRC8C、LRRC8D、GEMIN8P4、ZNF326、BARHL2、LOC149351、LOC100505840、ZNF644、LOC100996620、HFM1、CDC7、HSP90B3P、TGFBR3、BRDT、EPHX4、BTBD8、KIAA1107、C1orf146、GLMN、RPAP2、GFI1、EVI5、RPL5、FAM69A、SNORD21、SNORA66、MTF2、TMED5、CCDC18、LOC100131564、DR1、FNBP1L、BCAR3、LOC100129046、LOC100132240、MIR760、DNTTIP2、GCLM、ABCA4、ARHGAP29、LOC100505940、ABCD3、F3、MIR378G、SLC44A3、CNN3、LOC729970、ALG14、TMEM56、TMEM56-RWDD3、RWDD3、LOC100996630、FLJ31662、LOC100996635、PTBP2、DPYD、DPYD-AS1、MIR137HG、MIR2682、MIR137、LOC729987、SNX7、LPPR5、LOC100129620、LPPR4、PALMD、FRRS1、AGL、LOC730081、SLC35A3、HIAT1、SASS6、TRMT13、LRRC39、DBT、LOC100506007、RTCA、MIR553、CDC14A、GPR88、LOC100128787、VCAM1、EXTL2、SLC30A7、DPH5、LOC100506051、S1PR1、OLFM3、DNAJA1P5、COL11A1、RNPC3、AMY2B、ACTG1P4、AMY2A、AMY1A、AMY1B、AMY1C、LOC100129138、PRMT6、NTNG1、VAV3、VAV3-AS1、SLC25A24、NBPF4、LOC400768、NBPF6、FAM102B、HENMT1、PRPF38B、FNDC7、STXBP3、AKNAD1、SRG7、GPSM2、CLCC1、WDR47、TAF13、TMEM167B、SCARNA2、C1orf194、KIAA1324、SARS、CELSR2、PSRC1、
MYBPHL、SORT1、PSMA5、SYPL2、ATXN7L2、CYB561D1、AMIGO1、GPR61、GNAI3、MIR197、GNAT2、AMPD2、GSTM4、GSTM2、GSTM1、GSTM5、GSTM3、EPS8L3、CSF1、AHCYL1、STRIP1、ALX3、UBL4B、SLC6A17、KCNC4、LOC440600、RBM15、SLC16A4、LAMTOR5、PROK1、CYMP、KCNA10、KCNA2、KCNA3、CD53、LRIF1、DRAM2、CEPT1、DENND2D、CHI3L2、CHIAP2、CHIA、PIFO、PGCP1、OVGP1、WDR77、ATP5F1、C1orf162、ADORA3、LOC100129269、RAP1A、FAM212B、LOC100506343、DDX20、KCND3、LOC643355、CTTNBP2NL、MIR4256、WNT2B、ST7L、CAPZA1、MOV10、RHOC、PPM1J、FAM19A3、LOC128322、LOC100996702、SLC16A1、AKR7A2P1、LOC100506392、LOC100996251、LRIG2、LOC643441、MAGI3、PHTF1、RSBN1、PTPN22、AP4B1-AS1、BCL2L15、AP4B1、DCLRE1B、HIPK1、OLFML3、SYT6、TRIM33、BCAS2、DENND2C、AMPD1、NRAS、CSDE1、SIKE1、SYCP1、TSHB、TSPAN2、NGF、VANGL1、CASQ2、NHLH2、SLC22A15、MAB21L3、ATP1A1、ATP1A1OS、LOC100506459、CD58、MIR548AC、IGSF3、MIR320B1、CD2、PTGFRN、CD101、TTF2、MIR942、TRIM45、LOC100506478、VTCN1、MAN1A2、LOC100996263、FAM46C、GDAP2、WDR3、SPAG17、TBX15、WARS2、HAO2、HSD3B2、HSD3B1、HSD3BP4、LINC00622、ZNF697、PHGDH、HMGCS2、REG4、NBPF7、ADAM30、NOTCH2、LOC100132913、FAM72B、HIST2H2BA、LOC100996318、FCGR1B、EMBP1、MIR3118-1、ANKRD20A12P、MIR3118-2、MIR3118-3、LOC100130000、LOC100286793、LOC100996473、PPIAL4G、FAM72D、SRGAP2B、LINC00623、LOC730256、PPIAL4B、LOC728875、PFN1P2、LOC653513、NBPF9、PDE4DIP、LOC100996517、NUDT4P1、NOTCH2NL、NBPF10、HFE2、TXNIP、POLR3GL、ANKRD34A、LIX1L、RBM8A、GNRHR2、PEX11B、ITGA10、ANKRD35、PIAS3、NUDT17、POLR3C、RNF115、CD160、PDZK1、GPR89A、GPR89C、PDZK1P1、RNU1-9、NBPF11、LOC100506011、LOC100509195、HYDIN2、LOC100996529、LOC728989、PRKAB2、PDIA3P、FMO5、CHD1L、LINC00624、BCL9、ACP6、GJA5、GJA8、GPR89B、RNU1-6、NBPF24、LOC100505824、MIR5087、LOC100996555、FLJ39739、LOC100132999、PPIAL4A、NBPF14、PPIAL4D、NBPF15、PPIAL4E、NBPF16、PPIAL4F、FLJ37786、LOC645166、RNU1-5、LOC388692、FCGR1C、FAM72C、PPIAL4C、FAM91A2、LOC642441、LOC644634、HIST2H2BF、FCGR1A、HIST2H3D、HIST2H4A、HIST2H3C、HIST2H2AA3、HIST2H2BC、HIST2H2AA4、HIST2H3A、HIST2H4B、HIST2H2BE、HIST2H2AC、HIST2H2AB、BOLA1、SV2A、SF3B4、MTMR11、OTUD7B、VPS45、PLEKHO1、ANP32E、CA14、APH1A、C1orf54、C1orf51、MRPS21、PRPF3、RPRD2、TARS2、ECM1、LINC00568、ADAMTSL4、LOC100996516、MIR4257、MCL1、ENSA、GOLPH3L、HORMAD1、CTSS、CTSK、ARNT、LOC100996521、SETDB1、CERS2、ANXA9、FAM63A、PRUNE、BNIPL、C1orf56、CDC42SE1、MLLT11、GABPB2、SEMA6C、TNFAIP8L2-SCNM1、TNFAIP8L2、LYSMD1、SCNM1、TMOD4、
VPS72、PIP5K1A、PSMD4、LOC100507670、ZNF687、PI4KB、RFX5、SELENBP1、PSMB4、POGZ、CGN、TUFT1、MIR554、SNX27、CELF3、RIIAD1、MRPL9、OAZ3、TDRKH、LINGO4、RORC、C2CD4D、LOC100132111、THEM5、THEM4、S100A10、S100A11、LOC100131107、TCHHL1、TCHH、RPTN、HRNR、FLG、FLG-AS1、FLG2、CRNN、LCE5A、CRCT1、LCE3E、LCE3D、LCE3C、LCE3B、LCE3A、LCE2D、LCE2C、LCE2B、LCE2A、LCE4A、C1orf68、KPRP、LCE1F、LCE1E、LCE1D、LCE1C、LCE1B、LCE1A、LCE6A、SMCP、IVL、SPRR4、SPRR1A、SPRR3、SPRR1B、SPRR2D、SPRR2A、SPRR2B、SPRR2E、SPRR2F、SPRR2C、SPRR2G、LELP1、PRR9、LOR、PGLYRP3、PGLYRP4、S100A9、S100A12、S100A8、S100A7A、S100A7L2、S100A7、S100A6、S100A5、S100A4、S100A3、S100A2、S100A16、S100A14、S100A13、S100A1、CHTOP、SNAPIN、ILF2、NPR1、INTS3、SLC27A3、GATAD2B、DENND4B、CRTC2、SLC39A1、CREB3L4、JTB、RAB13、RPS27、NUP210L、MIR5698、TPM3、MIR190B、C1orf189、C1orf43、UBAP2L、HAX1、AQP10、ATP8B2、IL6R、SHE、TDRD10、UBE2Q1、CHRNB2、ADAR、KCNN3、PMVK、PBXIP1、PYGO2、SHC1、CKS1B、MIR4258、FLAD1、LENEP、ZBTB7B、DCST2、DCST1、LOC100505666、ADAM15、EFNA4、EFNA3、EFNA1、SLC50A1、DPM3、KRTCAP2、TRIM46、MUC1、MIR92B、THBS3、MTX1、GBAP1、GBA、FAM189B、SCAMP3、CLK2、HCN3、PKLR、FDPS、RUSC1-AS1、RUSC1、ASH1L、MIR555、POU5F1P4、ASH1L-AS1、MSTO1、YY1AP1、DAP3、MSTO2P、GON4L、SYT11、RIT1、KIAA0907、SNORA42、SCARNA4、RXFP4、ARHGEF2、SSR2、UBQLN4、LAMTOR2、RAB25、MEX3A、LMNA、SEMA4A、SLC25A44、PMF1-BGLAP、PMF1、BGLAP、PAQR6、SMG5、TMEM79、C1orf85、VHLL、CCT3、TSACC、RHBG、C1orf61、MIR9-1、MEF2D、IQGAP3、TTC24、APOA1BP、GPATCH4、HAPLN2、BCAN、NES、CRABP2、ISG20L2、RRNAD1、MRPL24、HDGF、PRCC、SH2D2A、NTRK1、INSRR、PEAR1、LRRC71、ARHGEF11、MIR765、ETV3L、ETV3、CYCSP52、FCRL5、FCRL4、FCRL3、FCRL2、FCRL1、CD5L、KIRREL、KIRREL-IT1、LOC646268、CD1D、LOC100505799、CD1A、CD1C、CD1B、CD1E、OR10T2、OR10K2、OR10K1、OR10R2、OR6Y1、OR6P1、OR10X1、OR10Z1、SPTA1、OR6K2、OR6K3、OR6K6、OR6N1、OR6N2、MNDA、PYHIN1、IFI16、AIM2、CADM3、LOC100131825、DARC、FCER1A、OR10J3、OR10J1、OR10J5、APCS、CRP、DUSP23、FCRL6、SLAMF8、C1orf204、VSIG8、CCDC19、TAGLN2、IGSF9、SLAMF9、LOC100505633、PIGM、KCNJ10、KCNJ9、IGSF8、ATP1A2、ATP1A4、CASQ1、PEA15、DCAF8、LOC100287049、PEX19、COPA、SUMO1P3、NCSTN、NHLH1、VANGL2、SLAMF6、CD84、SLAMF1、CD48、SLAMF7、LY9、CD244、ITLN1、ITLN2、F11R、TSTD1、USF1、ARHGAP30、PVRL4、KLHDC9、PFDN2、NIT1、DEDD、UFC1、USP21、PPOX、B4GALT3、ADAMTS4、NDUFS2、FCER1G、APOA2、TOMM40L、MIR5187、NR1I3、PCP4L1、MPZ、SDHC、C1orf192、FCGR2A、HSPA6、FCGR3A、
FCGR2C、HSPA7、FCGR3B、FCGR2B、RPL31P11、FCRLA、FCRLB、DUSP12、ATF6、OLFML2B、NOS1AP、MIR4654、MIR556、C1orf111、C1orf226、SH2D1B、UHMK1、UAP1、DDR2、HSD17B7、C1orf110、RGS4、RGS5、NUF2、PBX1、LOC100505795、LMX1A、RXRG、LOC400794、LRRC52、MGST3、LOC100505828、ALDH9A1、LOC440700、TMCO1、UCK2、MIR3658、FAM78B、MIR921、FMO9P、POGK、TADA1、ILDR2、MAEL、GPA33、DUSP27、POU2F1、CD247、CREG1、RCSD1、LOC100128751、MPZL1、ADCY10、MPC2、DCAF6、MIR1255B2、GPR161、TIPRL、SFT2D2、ANKRD36BP1、LOC100996595、TBX19、MIR557、LOC100505918、XCL2、XCL1、DPT、LINC00626、ATP1B1、NME7、BLZF1、C1orf114、SLC19A2、LOC100287813、F5、SELP、SELL、SELE、METTL18、C1orf112、SCYL3、KIFAP3、METTL11B、MIR3119-1、MIR3119-2、LOC284688、GORAB、PRRX1、LOC100127910、C1orf129、FMO3、MIR1295A、MIR1295B、FMO6P、FMO2、FMO1、FMO4、TOP1P1、PRRC2C、MYOC、VAMP4、METTL13、DNM3、DNM3OS、MIR214、MIR3120、MIR199A2、LOC100505991、C1orf105、PIGC、SUCO、FASLG、TNFSF18、TNFSF4、LOC100506023、PRDX6、SLC9C2、ANKRD45、LOC730159、KLHL20、CENPL、DARS2、GAS5-AS1、GAS5、SNORD81、SNORD47、SNORD80、SNORD79、SNORD78、SNORD44、SNORD77、SNORD76、SNORD75、SNORD74、ZBTB37、SERPINC1、RC3H1、RABGAP1L、GPR52、CACYBP、MRPS14、TNN、KIAA0040、TNR、RFWD2、SCARNA3、PAPPA2、ASTN1、MIR488、FAM5B、LOC100506128、SEC16B、LOC730102、RASAL2-AS1、RASAL2、LINC00083、TEX35、C1orf220、MIR4424、RALGPS2、ANGPTL1、FAM20B、TOR3A、ABL2、SOAT1、AXDND1、NPHS2、TDRD5、LOC100506206、FAM163A、TOR1AIP2、TOR1AIP1、CEP350、QSOX1、FLJ23867、LHX4、LOC100527964、ACBD6、MIR3121、XPR1、KIAA1614、STX6、MR1、IER5、GM140、CACNA1E、ZNF648、GLUL、TEDDM1、LINC00272、RGSL1、RNASEL、RGS16、LOC284648、RGS8、NPL、DHX9、SHCBP1L、LAMC1、LAMC2、NMNAT2、SMG7-AS1、SMG7、NCF2、ARPC5、RGL1、APOBEC4、GLT25D2、TSEN15、C1orf21、EDEM3、FAM129A、RNF2、TRMT1L、LOC100996636、SWT1、IVNS1ABP、LOC100288079、HMCN1、PRG4、TPR、C1orf27、OCLM、PDC、PTGS2、PLA2G4A、FAM5C、LOC440704、LOC100652834、RGS18、RGS21、RGS1、RGS13、MIR4426、RGS2、UCHL5、TROVE2、GLRX2、CDC73、MIR1278、B3GALT2、KCNT2、MIR4735、CFH、CFHR3、CFHR1、CFHR4、CFHR2、CFHR5、F13B、ASPM、ZBTB41、CRB1、DENND1B、C1orf53、LHX9、NEK7、ATP6V1G3、PTPRC、LOC100131234、MIR181B1、MIR181A1、NR5A2、FAM58BP、C1orf98、ZNF281、KIF14、DDX59、CAMSAP2、GPR25、C1orf106、KIF21B、LOC100506546、CACNA1S、ASCL5、TMEM9、IGFN1、PKP1、TNNT2、LAD1、TNNI1、PHLDA3、CSRP1、RPS10P7、NAV1、MIR5191、MIR1231、IPO9、SHISA4、LMOD1、TIMM17A、RNPEP、ELF3、GPR37L1、ARL8A、PTPN7、PTPRVP、LGR6、UBE2T、
PPP1R12B、SYT2、KDM5B、KDM5B-AS1、LOC641515、LOC148709、RABIF、KLHL12、ADIPOR1、CYB5R1、TMEM183A、PPFIA4、MYOG、ADORA1、MYBPH、CHI3L1、CHIT1、LOC100506775、LOC730227、BTG2、FMOD、PRELP、OPTC、ATP2B4、SNORA77、LINC00260、LAX1、ZC3H11A、ZBED6、SNRPE、LINC00303、SOX13、ETNK2、REN、KISS1、GOLT1A、PLEKHA6、LINC00628、PPP1R15B、PIK3C2B、MDM4、LRRN2、NFASC、CNTN2、TMEM81、RBBP5、DSTYK、TMCC2、NUAK2、KLHDC8A、LEMD1-AS1、LEMD1、MIR135B、CDK18、LOC284578、MFSD4、ELK4、SLC45A3、NUCKS1、RAB7L1、SLC41A1、PM20D1、LOC284581、SLC26A9、LOC100505630、FAM72A、AVPR1B、C1orf186、LOC100505650、CTSE、SRGAP2、IKBKE、RASSF5、EIF2D、DYRK3、MAPKAPK2、IL10、IL19、IL20、IL24、FAIM3、PIGR、FCAMR、C1orf116、YOD1、PFKFB2、C4BPB、C4BPA、CD55、CR2、CR1、CR1L、CD46、MIR29C、MIR29B2、LOC148696、CD34、PLXNA2、LOC100506899、LOC100509303、MIR205HG、MIR205、CAMK1G、LAMB3、MIR4260、G0S2、HSD11B1、TRAF3IP3、C1orf74、IRF6、DIEXF、SYT14、SERTAD4-AS1、SERTAD4、HHAT、KCNH1、RCOR3、TRAF5、LINC00467、RD3、SLC30A1、NEK2、LPGAT1、INTS7、DTL、RPL21P28、MIR3122、PPP2R5A、SNORA16B、TMEM206、NENF、ATF3、FAM71A、BATF3、NSL1、TATDN3、C1orf227、FLVCR1-AS1、FLVCR1、VASH2、ANGEL2、RPS6KC1、LINC00538、PROX1、SMYD2、PTPN14、CENPF、KCNK2、KCTD3、USH2A、ESRRG、GPATCH2、SPATA17、LINC00210、RRP15、LOC728463、TGFB2、LOC643723、LYPLAL1、SLC30A10、EPRS、BPNT1、IARS2、MIR215、MIR194-1、RAB3GAP2、MIR664、SNORA36B、AURKAPS1、MARK1、C1orf115、MARC2、MARC1、HLX、C1orf140、DUSP10、HHIPL2、TAF1A、LOC100506161、MIA3、AIDA、BROX、FAM177B、DISP1、TLR5、SUSD4、C1orf65、CAPN8、CAPN2、TP53BP2、LOC100288102、LOC100287497、LOC100996486、FBXO28、DEGS1、NVL、MIR320B2、CNIH4、WDR26、MIR4742、CNIH3、DNAH14、LBR、ENAH、SRP9、EPHX1、TMEM63A、LEFTY1、PYCR2、LEFTY2、SDE2、H3F3A、ACBD3、MIXL1、LIN9、PARP1、C1orf95、ITPKB、ITPKB-IT1、PSEN2、ADCK3、CDC42BPA、ZNF678、LOC100130093、JMJD4、SNAP47、PRSS38、WNT9A、MIR5008、LOC728728、LOC100996502、WNT3A、LOC100506571、ARF1、MIR3620、C1orf35、MRPL55、GUK1、GJC2、C1orf148、IBA57、C1orf145、OBSCN、TRIM11、TRIM17、HIST3H3、HIST3H2A、HIST3H2BB、MIR4666A、RNF187、BTNL10、RNA5S1、RNA5S2、RNA5S3、RNA5S4、RNA5S5、RNA5S6、RNA5S7、RNA5S8、RNA5S9、RNA5S10、RNA5S11、RNA5S12、RNA5S13、RNA5S14、RNA5S15、RNA5S16、RHOU、DUSP5P1、RNA5S17、RAB4A、SPHAR、CCSAP、ACTA1、NUP133、ABCB10、TAF5L、URB2、GALNT2、PGBD5、COG2、AGT、CAPN9、C1orf198、TTC13、ARV1、FAM89A、MIR1182、TRIM67、LOC149373、C1orf131、GNPAT、EXOC8、SPRTN、EGLN1、SNRPD2P2、TSNAX-DISC1、TSNAX、LINC00582、
DISC1、DISC2、SIPA1L2、KIAA1383、NTPCR、PCNXL2、KIAA1804、KCNK1、MIR4427、SLC35F3、MIR4671、COA6、TARBP1、LOC100506795、IRF2BP2、LINC00184、LOC100506810、PP2672、TOMM20、SNORA14B、RBM34、ARID4B、MIR4753、GGPS1、TBCE、B3GALNT2、GNG4、LYST、MIR1537、NID1、GPR137B、ERO1LB、EDARADD、LGALS8、LGALS8-AS1、HEATR1、ACTN2、MTR、RYR2、MIR4428、LOC100130331、ZP4、LOC339535、CHRM3、CHRM3-AS2、RPS7P5、FMN2、GREM2、LOC100506929、RGS7、MIR3123、FH、KMO、OPN3、CHML、WDR64、EXO1、MAP1LC3C、PLD5、LOC100505955、LOC731275、CEP170、SDCCAG8、MIR4677、AKT3、LOC339529、ZNF238、LOC440742、C1orf100、ADSS、C1orf101、DESI2、COX20、HNRNPU-AS1、HNRNPU、EFCAB2、KIF26B、SMYD3、LOC255654、TFB2M、CNST、SCCPDH、LOC100130097、LOC149134、AHCTF1、ZNF695、ZNF670-ZNF695、ZNF670、ZNF669、C1orf229、ZNF124、MIR3916、VN1R5、ZNF496、NLRP3、OR2B11、OR2W5、GCSAML-AS1、OR2C3、GCSAML、OR2G2、OR2G3、OR13G1、OR6F1、OR1C1、OR14A16、OR11L1、TRIM58、OR2W3、OR2T8、OR2L13、OR2L8、OR2AK2、OR2L1P、OR2L5、OR2L2、OR2L3、OR2M1P、OR2M5、OR2M2、OR2M3、OR2M4、OR2T33、OR2T12、OR2M7、OR14C36、OR2T4、OR2T6、OR2T1、OR2T2、OR2T3、OR2T5、OR2G6、OR2T29、OR2T34、OR2T10、OR2T11、OR2T35、OR2T27、OR14I1、LYPD8、SH3BP5L、MIR3124、ZNF672、ZNF692、PGBD2、TUBB8、ZMYND11、DIP2C、MIR5699、C10orf108、LARP4B、LOC100288619、GTPBP4、IDI2、IDI2-AS1、IDI1、WDR37、LINC00200、ADARB2、LOC642422、ADARB2-AS1、LOC282980、LOC399708、PFKP、PITRM1、LOC100507034、KLF6、LOC100652988、LOC100507059、LOC100128356、LOC100216001、LOC338588、AKR1E2、TAKR、AKR1C1、AKR1C2、AKR1C3、AKR1CL1、AKR1C4、UCN3、TUBAL3、NET1、CALML5、LOC100132159、CALML3、ASB13、FAM208B、GDI2、ANKRD16、FBXO18、IL15RA、IL2RA、RBM17、PFKFB3、MIR3155A、MIR3155B、LOC399715、DKFZp667F0711、PRKCQ、LOC439949、LOC100507127、SFMBT2、ITIH5、ITIH2、KIN、ATP5C1、TAF3、FLJ45983、GATA3、LOC100507143、LOC100507163、SFTA1P、LOC254312、CELF2、LOC439950、CELF2-AS1、USP6NL、LOC100507213、ECHDC3、C10orf47、LOC219731、UPF2、DHTKD1、SEC61A2、MIR548AK、NUDT5、CDC123、CAMK1D、MIR4480、MIR4481、MIR548Q、LOC283070、CCDC3、OPTN、MCM10、RNU6-2、UCMA、PHYH、SEPHS1、BEND7、PRPF18、FRMD4A、MIR4293、MIR1265、FAM107B、CDNF、HSPA14、SUV39H2、DCLRE1C、MEIG1、LOC100289151、OLAH、ACBD7、C10orf111、RPP38、NMT2、LOC100192204、FAM171A1、ITGA8、FAM188A、PTER、C1QL3、RSU1、CUBN、TRDMT1、LOC100507347、VIM、ST8SIA6、LOC100128098、PTPLA、STAM、TMEM236、MIR511-1、MRC1、MIR511-2、SLC39A12、LOC100129213、CACNB2、NSUN6、ARL5B、PLXDC2、MIR4675、NEBL、C10orf113、LOC100128511、
RNU6-15、C10orf114、MIR1915、SKIDA1、MLLT10、DNAJC1、LOC100507445、EBLN1、LOC100130992、COMMD3-BMI1、COMMD3、BMI1、SPAG6、LOC100499489、LOC100289455、PIP4K2A、ARMC3、MSRB2、PTF1A、C10orf67、MIR1254-2、OTUD1、KIAA1217、MIR603、ARHGAP21、PRTFDC1、ENKUR、THNSL1、GPR158-AS1、GPR158、LOC100507531、MYO3A、GAD2、APBB1IP、LINC00264、LOC731789、PDSS1、ABI1、LINC00202、ANKRD26、YME1L1、MASTL、ACBD5、LRRC37A6P、PTCHD3、RAB18、MKX、ARMC4、MPP7、WAC-AS1、WAC、BAMBI、LOC100507605、C10orf126、LYZL1、LOC387647、SVIL、MIR604、MIR938、KIAA1462、MTPAP、MAP3K8、LYZL2、ZNF438、LOC100507663、ZEB1-AS1、ZEB1、LOC100996668、ARHGAP12、KIF5B、EPC1、CCDC7、C10orf68、ITGB1、NRP1、LOC100505583、PARD3、LOC100505601、CUL2、MIR3611、CREM、CCNY、GJD4、FZD8、MIR4683、ANKRD30A、MTRNR2L7、ZNF248、LOC100419868、ZNF25、ZNF33A、ZNF37A、LOC100129055、HSD17B7P2、SEPT7L、LOC399744、ACTR3BP5、LOC441666、LOC84856、ZNF37BP、ZNF33B、BMS1、MIR5100、RET、CSGALNACT2、RASGEF1A、FXYD4、HNRNPF、ZNF487P、LOC100996605、ZNF239、ZNF485、ZNF32-AS3、ZNF32、ZNF32-AS1、ZNF32-AS2、HNRNPA3P1、LINC00619、LOC100506835、LOC283033、LOC100506853、LOC100130539、CXCL12、TMEM72-AS1、TMEM72、RASSF4、C10orf10、C10orf25、ZNF22、RSU1P2、LOC338579、MIR3156-1、OR13A1、ALOX5、MARCH8、ZFAND4、FAM21C、AGAP4、PTPN20A、BMS1P1、GLUD1P7、FAM35B、SYT15、GPRIN2、PPYR1、LOC643650、LOC728643、ANXA8L1、FAM25B、AGAP10、BMS1P2、FAM35B2、LOC100996567、ANTXRL、ANXA8L2、FAM21B、CTSL1P2、BMS1P6、AGAP9、FAM25G、ANXA8、ZNF488、RBP3、GDF2、GDF10、PTPN20B、FRMPD2P1、BMS1P5、FAM25C、FRMPD2、MAPK8、ARHGAP22、WDFY4、LRRC18、MIR4294、VSTM4、LOC100506733、FAM170B、C10orf128、LOC100506769、C10orf71、DRGX、ERCC6、PGBD3、CHAT、SLC18A3、C10orf53、OGDHL、PARG、AGAP8、LOC728407、TIMM23B、AGAP7、MSMB、NCOA4、TIMM23、LOC100996610、LOC100652748、AGAP6、FAM21A、ASAH2、SGMS1、ASAH2B、A1CF、PRKG1、MIR605、CSTF2T、LOC100506939、DKK1、MBL2、PCDH15、MIR548F1、MTRNR2L5、ZWINT、MIR3924、IPMK、CISD1、UBE2D1、TFAM、BICC1、FAM133CP、LOC100507008、PHYHIPL、FAM13C、SLC16A9、M1、CCDC6、C10orf40、ANK3、CDK1、RHOBTB1、LOC100507058、TMEM26、C10orf107、ARID5B、RTKN2、ZNF365、ADO、EGR2、NRBF2、JMJD1C、MIR1296、LOC84989、REEP3、ANXA2P3、CTNNA3、LRRTM3、DNAJC12、SIRT1、HERC4、MYPN、ATOH7、PBLD、HNRNPH3、RUFY2、DNA2、LOC100996629、SLC25A16、TET1、CCAR1、SNORD98、MIR1254-1、STOX1、DDX50、DDX21、KIAA1279、SRGN、VPS26A、SUPV3L1、HKDC1、HK1、TACR2、TSPAN15、NEUROG3、C10orf35、COL13A1、H2AFY2、AIFM2、TYSND1、SAR1A、PPA1、
NPFFR1、LRRC20、EIF4EBP2、NODAL、PALD1、PRF1、ADAMTS14、TBATA、SGPL1、PCBD1、UNC5B、LOC728978、SLC29A3、CDH23、C10orf105、C10orf54、PSAP、CHST3、SPOCK2、ASCC1、ANAPC16、DDIT4、DNAJB12、MICU1、MCU、MIR4676、OIT3、PLA2G12B、P4HA1、NUDT13、ECD、FAM149B1、DNAJC9、DNAJC9-AS1、MRPS16、TTC18、ANXA7、MSS51、PPP3CB、USP54、MYOZ1、SYNPO2L、AGAP5、BMS1P4、GLUD1P3、SEC24C、FUT11、CHCHD1、ZSWIM8、LOC100507331、NDST2、CAMK2G、C10orf55、PLAU、VCL、AP3M1、ADK、KAT6B、DUPD1、DUSP13、SAMD8、VDAC2、COMTD1、ZNF503-AS1、ZNF503、ZNF503-AS2、MIR606、C10orf11、KCNMA1、DLG5、LOC100131132、LOC100128292、POLR3A、RPS24、LOC100132987、LOC283050、ZMIZ1、PPIF、ZCCHC24、EIF5AL1、SFTPA2、SFTPA1、LOC650623、LOC642361、LOC100288974、MBL1P、SFTPD、TMEM254-AS1、TMEM254、PLAC9、ANXA11、LOC439990、LOC100130698、MAT1A、DYDC1、DYDC2、FAM213A、TSPAN14、SH2D4B、NRG3、GHITM、C10orf99、CDHR1、LRIT2、LRIT1、RGR、LOC170425、FAM190B、GRID1-AS1、GRID1、MIR346、WAPAL、OPN4、LDB3、BMPR1A、MMRN2、SNCG、C10orf116、AGAP11、FAM25A、GLUD1、FAM35A、FAM22A、LOC728190、LOC439994、FAM22D、LOC728218、MIR4678、MINPP1、PAPSS2、ATAD1、CFL1P1、KLLN、PTEN、RNLS、LIPJ、LIPF、LIPK、LIPN、LIPM、ANKRD22、STAMBPL1、LOC100132116、ACTA2、FAS、FAS-AS1、MIR4679-2、MIR4679-1、CH25H、LIPA、IFIT2、IFIT3、IFIT1B、IFIT1、IFIT5、SLC16A12、PANK1、MIR107、FLJ37201、KIF20B、LOC643529、HTR7、RPP30、ANKRD1、LINC00502、NUDT9P1、PCGF5、LOC100188947、HECTD2、PPP1R3C、LOC100507633、TNKS2、FGFBP3、BTAF1、CPEB3、MARCH5、MARK2P9、IDE、KIF11、HHEX、EXOC6、CYP26C1、CYP26A1、MYOF、CEP55、FFAR4、RBP4、PDE6C、FRA10AC1、LGI1、SLC35G1、PIPSL、PLCE1、LOC100128054、NOC3L、TBC1D12、HELLS、CYP2C18、CYP2C19、CYP2C9、CYP2C8、C10orf129、PDLIM1、SORBS1、ALDH18A1、TCTN3、ENTPD1、LOC728558、C10orf131、CC2D2B、CCNJ、MIR3157、ZNF518A、BLNK、DNTT、OPALIN、TLL2、TM9SF3、PIK3AP1、RPL13AP5、MIR607、LCOR、C10orf12、SLIT1、LOC100505540、ARHGAP19-SLIT1、ARHGAP19、FRAT1、FRAT2、RRP12、PGAM1、EXOSC1、ZDHHC16、MMS19、UBTD1、ANKRD2、HOGA1、C10orf62、MORN4、PI4K2A、AVPI1、MARVELD1、ZFYVE27、SFRP5、LOC100505561、GOLGA7B、CRTAC1、R3HCC1L、LOXL4、PYROXD2、MIR1287、HPS1、MIR4685、HPSE2、CNNM1、GOT1、NKX2-3、SLC25A28、ENTPD7、COX15、CUTC、ABCC2、DNMBP、DNMBP-AS1、CPN1、ERLIN1、CHUK、CWF19L1、SNORA12、BLOC1 S2、PKD2L1、SCD、LINC00263、WNT8B、SEC31B、NDUFB8、HIF1AN、PAX2、FAM178A、SEMA4G、MIR608、MRPL43、C10orf2、LZTS2、PDZD7、SFXN3、KAZALD1、TLX1NB、TLX1、LBX1、FLJ41350、BTRC、POLL、DPCD、MIR3158-1、MIR3158-2、FBXW4、FGF8、
NPM3、MGEA5、LOC100289509、KCNIP2、C10orf76、HPS6、LDB1、PPRC1、NOLC1、ELOVL3、PITX3、GBF1、NFKB2、PSD、FBXL15、CUEDC2、MIR146B、LOC100505761、C10orf95、TMEM180、ACTR1A、SUFU、TRIM8、ARL3、SFXN2、WBP1L、CYP17A1、CYP17A1-AS1、C10orf32、C10orf32-AS3MT、AS3MT、CNNM2、NT5C2、LOC729020、INA、PCGF6、TAF5、USMG5、MIR1307、PDCD11、CALHM2、CALHM1、CALHM3、NEURL、SH3PXD2A、LOC100505839、OBFC1、SLK、COL17A1、MIR936、SFR1、WDR96、MIR609、GSTO1、MIR4482-1、GSTO2、ITPRIP、LOC100505869、CCDC147、SORCS3、SORCS1、XPNPEP1、LOC100505933、ADD3、MXI1、SMNDC1、DUSP5、SMC3、RBM20、LOC282997、PDCD4、MIR4680、BBIP1、SHOC2、RPL13AP6、MIR548E、ADRA2A、GPAM、TECTB、GUCY2GP、ACSL5、ZDHHC6、VTI1A、MIR4295、TCF7L2、HABP2、NRAP、CASP7、PLEKHS1、MIR4483、DCLRE1A、NHLRC2、ADRB1、C10orf118、MIR2110、TDRD1、VWA2、AFAP1L2、ABLIM1、FAM160B1、TRUB1、ATRNL1、GFRA1、CCDC172、PNLIPRP3、PNLIP、PNLIPRP1、PNLIPRP2、C10orf82、HSPA12A、ENO4、KIAA1598、VAX1、MIR3663、KCNK18、SLC18A2、PDZD8、EMX2OS、EMX2、LOC100996346、RAB11FIP2、CASC2、FAM204A、LOC100506126、PRLHR、CACUL1、NANOS1、EIF3A、SNORA19、FAM45A、SFXN4、PRDX3、GRK5、MIR4681、RGS10、TIAL1、BAG3、INPP5F、MCMBP、SEC23IP、MIR4682、PPAPDC1A、WDR11-AS1、WDR11、FGFR2、ATE1、LOC100130887、NSMCE4A、TACC2、BTBD16、PLEKHA1、MIR3941、ARMS2、HTRA1、DMBT1、C10orf120、FLJ46361、CUZD1、FAM24B-CUZD1、FAM24B、LOC399815、FAM24A、C10orf88、PSTK、IKZF5、ACADSB、HMX3、HMX2、BUB3、GPR26、CPXM2、CHST15、OAT、NKX1-2、LHPP、LOC100506255、FAM53B、METTL10、FAM175B、ZRANB1、CTBP2、MIR4296、LOC100169752、TEX36、LOC283038、FLJ37035、C10orf137、MMP21、UROS、MIR4484、BCCIP、DHX32、FANK1、ADAM12、C10orf90、LOC728065、DOCK1、FAM196A、NPS、FOXI2、CLRN3、PTPRE、MKI67、MGMT、EBF3、MIR4297、LOC387723、CTAGE7P、GLRX3、MIR378C、TCERG1L、FLJ46300、PPP2R2D、BNIP3、JAKMIP3、DPYSL4、STK32C、LOC100506057、LRRC27、PWWP2B、C10orf91、INPP5A、NKX6-2、TTC40、LOC100289424、LOC399829、GPR123、KNDC1、UTF1、VENTX、MIR202、ADAM8、TUBGCP2、ZNF511、CALY、PRAP1、FUOM、ECHS1、MIR3944、PAOX、MTG1、SPRN、LOC619207、CYP2E1、SYCE1、SPRNP1、FRG2B、LOC100133161、SCGB1C1、ODF3、BET1L、RIC8A、SIRT3、PSMD13、NLRP6、ATHL1、IFITM5、IFITM2、IFITM1、IFITM3、B4GALNT4、PKP3、SIGIRR、ANO9、PTDSS2、RNH1、HRAS、LRRC56、C11orf35、LOC692247、RASSF7、MIR210HG、MIR210、LOC143666、PHRF1、IRF7、CDHR5、SCT、DRD4、DEAF1、TMEM80、EPS8L2、TALDO1、PDDC1、LOC100506518、NS3BP、CEND1、SLC25A22、PIDD、RPLP2、SNORA52、PNPLA2、EFCAB4A、CD151、POLR2L、TSPAN4、
CHID1、AP2A2、MUC6、MUC2、MUC5B、TOLLIP、LOC255512、BRSK2、MOB2、DUSP8、LOC338651、KRTAP5-1、KRTAP5-2、KRTAP5-3、KRTAP5-4、KRTAP5-5、FAM99A、FAM99B、LOC100505570、KRTAP5-6、IFITM10、CTSD、SYT8、TNNI2、LSP1、MIR4298、TNNT3、MRPL23、MRPL23-AS1、H19、MIR675、INS-IGF2、IGF2、MIR483、IGF2-AS、INS、TH、MIR4686、ASCL2、C11orf21、TSPAN32、CD81、TSSC4、TRPM5、KCNQ1、KCNQ1OT1、KCNQ1DN、CDKN1C、SLC22A18AS、SLC22A18、PHLDA2、NAP1L4、SNORA54、LOC100505870、CARS、OSBPL5、MRGPRG、MRGPRG-AS1、MRGPRE、ZNF195、LOC650368、OR7E12P、TRPC2、ART5、ART1、CHRNA10、NUP98、PGAP2、RHOG、STIM1、MIR4687、RRM1、LOC100506082、OR52B4、TRIM21、OR52K2、OR52K1、OR52M1、C11orf40、OR52I2、OR52I1、TRIM68、OR51D1、OR51E1、OR51E2、OR51F1、OR52R1、OR51F2、OR51S1、OR51T1、OR51A7、OR51G2、OR51G1、OR51A4、OR51A2、MMP26、OR51L1、OR52J3、OR52E2、LOC100506101、OR52A5、OR52A1、OR51V1、HBB、HBD、HBBP1、HBG1、HBG2、HBE1、OR51B4、OR51B2、OR51B5、OR51B6、OR51M1、OR51Q1、OR51I1、OR51I2、OR52D1、UBQLN3、UBQLNL、OR52H1、OR52B6、TRIM6、TRIM6-TRIM34、TRIM34、TRIM5、TRIM22、OR56B1、OR52N4、OR52N5、OR52N1、OR52N2、OR52E6、OR52E8、OR52E4、OR56A3、OR56A5、OR52L1、OR56A4、OR56A1、OR56B4、OR52B2、OR52W1、C11orf42、FAM160A2、CNGA4、CCKBR、PRKCDBP、SMPD1、APBB1、HPX、TRIM3、ARFIP2、FXC1、DNHD1、RRP8、ILK、TAF10、TPP1、DCHS1、MRPL17、GVINP1、OR2AG2、OR2AG1、OR6A2、OR10A5、OR10A2、OR10A4、OR2D2、OR2D3、ZNF215、ZNF214、NLRP14、RBMXL2、LOC100506238、MIR302E、SYT9、LOC100506258、OLFML1、PPFIBP2、CYB5R2、OVCH2、OR5P2、OR5P3、OR5E1P、LOC283299、OR10A6、OR10A3、NLRP10、EIF3F、TUB、RIC3、LMO1、STK33、TRIM66、RPL27A、SNORA3、SNORA45、ST5、AKIP1、C11orf16、ASCL3、TMEM9B、NRIP3、SCUBE2、MIR5691、KRT8P41、DENND5A、TMEM41B、IPO7、SNORA23、LOC644656、ZNF143、WEE1、SWAP70、LOC440028、SBF2-AS1、SBF2、ADM、AMPD3、MTRNR2L8、MIR4485、RNF141、MRVI1-AS1、LYVE1、MRVI1、CTR9、EIF4G2、SNORD97、ZBED5、LOC729013、GALNTL4、CSNK2A1P、MIR4299、USP47、DKK3、MICAL2、MICALCL、PARVA、TEAD1、LOC100506305、LOC100506352、RASSF10、ARNTL、LOC100996618、BTBD10、PTH、FAR1、SPON1、RRAS2、COPB1、PSMA1、PDE3B、CYP2R1、CALCA、CALCB、INSC、SOX6、C11orf58、PLEKHA7、OR7E14P、RPS13、SNORD14A、SNORD14B、PIK3C2A、NUCB2、NCR3LG1、KCNJ11、ABCC8、USH1C、OTOG、MYOD1、KCNC1、SERGEF、TPH1、SAAL1、SAA3P、MRGPRX3、MRGPRX4、LOC494141、SAA4、SAA2-SAA4、SAA2、SAA1、HPS5、GTF2H1、MIR3159、LDHA、LDHC、LDHAL6A、TSG101、UEVLD、SPTY2D1-AS1、SPTY2D1、TMEM86A、IGSF22、PTPN5、MRGPRX1、MRGPRX2、ZDHHC13、
CSRP3、E2F8、NAV2、NAV2-AS5、NAV2-AS4、MIR4486、LOC100126784、MIR4694、DBX1、HTATIP2、PRMT3、SLC6A5、NELL1、ANO5、SLC17A6、FANCF、GAS2、SVIP、LOC100500938、LUZP2、ANO3、MUC15、SLC5A12、FIBIN、BBOX1、CCDC34、LGR4、LIN7C、BDNF-AS、BDNF、KIF18A、MIR610、METTL15、KCNA4、FSHB、ARL14EP、MPPED2、DCDC5、LOC100508736、DCDC1、DNAJC24、IMMP1L、ELP4、PAX6、DKFZp686K1684、LOC100506675、RCN1、WT1、WT1-AS、EIF3M、CCDC73、PRRG4、QSER1、DEPDC7、TCP11L1、LINC00294、CSTF3、LOC338739、HIPK3、KIAA1549L、C11orf91、CD59、FBXO3、LOC100507109、LMO2、CAPRIN1、NAT10、ABTB2、CAT、ELF5、EHF、APIP、PDHX、MIR1343、LOC100507144、CD44、SLC1A2、PAMR1、FJX1、TRIM44、LDLRAD3、MIR3973、COMMD9、PRR5L、TRAF6、RAG1、RAG2、C11orf74、LRRC4C、LOC100507205、HNRNPKP3、API5、TTC17、MIR670、LOC100507261、LOC100131381、MIR129-2、HSD17B12、ALKBH3、SEC14L1P1、LOC100507300、C11orf96、ACCSL、ACCS、EXT2、ALX4、CD82、TSPAN18、TP53I11、LOC221122、PRDM11、SYT13、CHST1、LOC100507384、DKFZp779M0652、SLC35C1、CRY2、MAPK8IP1、C11orf94、PEX16、GYLTL1B、PHF21A、CREB3L1、DGKZ、MIR4688、MDK、CHRM4、AMBRA1、MIR3160-1、MIR3160-2、HARBI1、ATG13、ARHGAP1、ZNF408、F2、CKAP5、MIR5582、SNORD67、LRP4-AS1、LRP4、C11orf49、ARFGAP2、PACSIN3、DDB2、ACP2、NR1H3、MADD、MYBPC3、SPI1、LOC100507417、MIR4487、SLC39A13、PSMC3、RAPSN、CELF1、PTPMT1、KBTBD4、NDUFS3、FAM180B、C1QTNF4、MTCH2、AGBL2、FNBP4、NUP160、PTPRJ、MIR3161、OR4B1、OR4X2、OR4X1、OR4S1、OR4C3、OR4A47、TRIM51GP、TRIM49B、TRIM64C、FOLH1、LOC440040、OR4C13、OR4C12、LOC441601、LOC646813、OR4A5、OR4C46、TRIM48、TRIM51HP、OR4A16、OR4A15、OR4C15、OR4C16、OR4C11、OR4P4、OR4S2、OR4C6、OR5D13、OR5D14、OR5L1、OR5D18、OR5L2、OR5D16、TRIM51、OR5W2、OR5I1、OR10AG1、OR7E5P、OR5F1、OR5AS1、OR8I2、OR8H2、OR8H3、OR8J3、OR8K5、OR5J2、OR5T2、OR5T3、OR5T1、OR8H1、OR8K3、OR8K1、OR8J1、OR8U1、OR5R1、OR5M9、OR5M3、OR5M8、OR5M11、OR5M10、OR5M1、OR5AP2、OR5AR1、OR9G1、OR9G4、OR5AK2、OR5AK4P、LRRC55、APLNR、TNKS1BP1、SSRP1、P2RX3、PRG3、PRG2、SLC43A3、RTN4RL2、SLC43A1、TIMM10、SMTNL1、UBE2L6、SERPING1、MIR130A、YPEL4、CLP1、ZDHHC5、MED19、TMX2、TMX2-CTNND1、C11orf31、BTBD18、CTNND1、OR9Q1、OR6Q1、OR9I1、OR9Q2、OR1S2、OR1S1、OR10Q1、OR10W1、OR5B17、OR5B3、OR5B2、OR5B12、OR5B21、LPXN、ZFP91-CNTF、ZFP91、CNTF、GLYAT、GLYATL2、LOC100287413、GLYATL1、LOC283194、FAM111B、FAM111A、DTX4、MPEG1、OR5AN1、OR5A2、OR5A1、OR4D6、OR4D10、OR4D11、OR4D9、OSBP、MIR3162、PATL1、OR10V1、OR10V2P、STX3、MRPL16、GIF、TCN1、PLAC1L、MS4A3、MS4A2、
MS4A6A、MS4A4E、MS4A4A、MS4A6E、MS4A7、MS4A14、MS4A5、MS4A1、MS4A12、MS4A13、LINC00301、MS4A8B、MS4A15、MS4A10、CCDC86、PTGDR2、ZP1、PRPF19、TMEM109、TMEM132A、SLC15A3、CD6、CD5、VPS37C、PGA3、PGA4、PGA5、VWCE、DDB1、DAK、CYBASC3、TMEM138、TMEM216、CPSF7、SDHAF2、PPP1R32、MIR4488、LRRC10B、SYT7、RPLP0P2、DAGLA、C11orf9、DKFZP434K028、LOC100129473、C11orf10、MIR611、FEN1、FADS1、MIR1908、FADS2、FADS3、RAB3IL1、BEST1、FTH1、LOC100507521、INCENP、SCGB1D1、SCGB2A1、SCGB1D2、SCGB2A2、SCGB1D4、ASRGL1、SCGB1A1、AHNAK、EEF1G、TUT1、MTA2、EML3、ROM1、B3GAT3、GANAB、INTS5、C11orf48、METTL12、SNORA57、C11orf83、UBXN1、LRRN4CL、HNRNPUL2-BSCL2、BSCL2、GNG3、HNRNPUL2、TTC9C、ZBTB3、POLR2G、TAF6L、TMEM179B、TMEM223、NXF1、STX5、WDR74、RNU2-2、SNHG1、SNORD22、SNORD31、SNORD30、SNORD29、SNORD28、SNORD27、SNORD26、SNORD25、SLC3A2、CHRM1、SLC22A6、SLC22A8、SLC22A24、SLC22A25、SLC22A10、SLC22A9、HRASLS5、LGALS12、RARRES3、HRASLS2、PLA2G16、ATL3、RTN3、C11orf95、C11orf84、MARK2、RCOR2、NAA40、RNU6-45、COX8A、OTUB1、MACROD1、FLRT1、STIP1、FERMT3、TRPT1、NUDT22、DNAJC4、VEGFB、FKBP2、PPP1R14B、PLCB3、BAD、GPR137、KCNK4、C11orf20、ESRRA、TRMT112、PRDX5、CCDC88B、RPS6KA4、MIR1237、LOC100996455、SLC22A11、SLC22A12、NRXN2、RASGRP2、PYGM、SF1、MAP4K2、MEN1、CDC42BPG、EHD1、MIR192、MIR194-2、ATG2A、PPP2R5B、GPHA2、C11orf85、BATF2、ARL2-SNX15、ARL2、SNX15、SAC3D1、NAALADL1、CDCA5、ZFPL1、LOC100130348、VPS51、TM7SF2、ZNHIT2、FAU、MRPL49、SYVN1、SPDYC、CAPN1、SLC22A20、POLA2、CDC42EP2、DPF2、TIGD3、SLC25A45、FRMD8、NEAT1、MIR612、MALAT1、SCYL1、LTBP3、LOC254100、SSSCA1、FAM89B、EHBP1L1、KCNK7、MAP3K11、PCNXL3、MIR4690、SIPA1、MIR4489、RELA、KAT5、RNASEH2C、AP5B1、OVOL1、SNX32、CFL1、MUS81、EFEMP2、CTSW、FIBP、CCDC85B、FOSL1、C11orf68、DRAP1、TSGA10IP、SART1、EIF1AD、BANF1、CST6、CATSPER1、GAL3ST3、SF3B2、PACS1、KLC2、RAB1B、CNIH2、YIF1A、TMEM151A、CD248、RIN1、BRMS1、B3GNT1、SLC29A2、LOC100505504、NPAS4、MRPL11、PELI3、DPP3、BBS1、ZDHHC24、ACTN3、CTSF、CCDC87、CCS、RBM14、RBM14-RBM4、RBM4、RBM4B、SPTBN2、C11orf80、RCE1、PC、LRFN4、MIR3163、C11orf86、SYT12、RHOD、KDM2A、ADRBK1、ANKRD13D、SSH3、LOC100130987、POLD4、CLCF1、RAD9A、PPP1CA、TBC1D10C、CARNS1、RPS6KB2、PTPRCAP、CORO1B、GPR152、CABP4、TMEM134、AIP、PITPNM1、CDK2AP2、CABP2、GSTP1、NDUFV1、LOC100996505、DOC2GP、NUDT8、TBX10、ACY3、ALDH3B2、FAM86C2P、RNU6-46、UNC93B1、ALDH3B1、NDUFS8、MIR4691、TCIRG1、CHKA、SUV420H1、C11orf24、LRP5、PPP6R3、GAL、MTL5、CPT1A、MRPL21、
IGHMBP2、MRGPRD、MRGPRF、TPCN2、MIR3164、MYEOV、LOC100505834、LOC100996515、CCND1、ORAOV1、FGF19、FGF4、FGF3、LOC100127946、ANO1-AS2、ANO1、FADD、PPFIA1、MIR548K、CTTN、SHANK2、SHANK2-AS1、SHANK2-AS3、MIR3664、FLJ42102、DHCR7、NADSYN1、KRTAP5-7、KRTAP5-8、KRTAP5-9、KRTAP5-10、KRTAP5-11、FAM86C1、ZNF705E、DEFB108B、LOC100133315、LOC100129216、RNF121、IL18BP、NUMA1、MIR3165、LRTOMT、LAMTOR1、ANAPC15、FOLR3、FOLR1、FOLR2、INPPL1、PHOX2A、CLPB、PDE2A、MIR139、ARAP1、ARAP1-AS2、STARD10、MIR4692、ATG16L2、FCHSD2、P2RY2、P2RY6、LOC100287837、ARHGEF17、RELT、FAM168A、PLEKHB1、RAB6A、MRPL48、COA4、PAAF1、DNAJB13、UCP2、UCP3、C2CD3、PPME1、P4HA3、PGM2L1、MIR548AL、KCNE3、LIPT2、LOC100287896、POLD3、CHRDL2、MIR4696、RNF169、XRRA1、SPCS2、NEU3、OR2AT4、SLCO2B1、TPBGL、ARRB1、MIR326、RPS3、SNORD15A、SNORD15B、KLHL35、GDPD5、SERPINH1、MAP6、MOGAT2、LOC283214、DGAT2、LOC100506113、UVRAG、WNT11、PRKRIR、LOC100996578、C11orf30、LRRC32、GUCY2EP、TSKU、ACER3、B3GNT6、CAPN5、OMP、MYO7A、GDPD4、PAK1、AQP11、CLNS1A、RSF1、AAMDC、INTS4、NDUFC2-KCTD14、KCTD14、THRSP、NDUFC2、ALG8、LOC100289388、KCTD21、USP35、GAB2、NARS2、TENM4、MIR708、MIR5579、MIR4300、FAM181B、PRCP、C11orf82、RAB30、SNORA70E、LOC100506233、PCF11、LOC100506282、ANKRD42、CCDC90B、DLG2、TMEM126B、TMEM126A、CREBZF、CCDC89、SYTL2、CCDC83、PICALM、EED、C11orf73、CCDC81、ME3、PRSS23、OR7E2P、FZD4、LOC100506368、TMEM135、RAB38、MIR3166、CTSC、GRM5-AS1、GRM5、RNU6-16、TYR、NOX4、FOLH1B、TRIM77P、TRIM49、TRIM64B、TRIM49DP、TRIM49L1、TRIM64、TRIM51EP、TRIM53AP、TRIM49C、UBTFL1、NAALAD2、CHORDC1、MIR4490、MIR1261、FAT3、MTNR1B、SLC36A4、CCDC67、C11orf75、KIAA1731、SCARNA9、SNORA25、SNORA32、SNORD6、SNORA1、SNORA8、SNORD5、SNORA18、MIR1304、SNORA40、TAF1D、C11orf54、MED17、VSTM5、HEPHL1、PANX1、FOLR4、GPR83、MRE11A、MIR548L、ANKRD49、LOC643037、FUT4、PIWIL4、AMOTL1、CWC15、KDM4D、KDM4E、SRSF8、ENDOD1、SESN3、LOC100129203、FAM76B、CEP57、MTMR2、MAML2、LOC100131541、MIR1260B、CCDC82、JRKL、JRKL-AS1、CNTN5、ARHGAP42、TMEM133、PGR、LOC101054525、TRPC6、MIR3920、ANGPTL5、KIAA1377、C11orf70、YAP1、BIRC3、BIRC2、TMEM123、MMP7、MMP20、MMP27、MMP8、MMP10、WTAPP1、MMP1、MMP3、MMP12、MMP13、DCUN1D5、DYNC2H1、MIR4693、PDGFD、DDI1、CASP12、LOC643733、CASP4、CASP5、CASP1、CARD16、CARD17、CARD18、GRIA4、MSANTD4、KBTBD3、AASDHPPT、GUCY1A2、CWF19L2、ALKBH8、ELMOD1、LOC643923、SLN、SLC35F2、RAB39A、CUL5、ACAT1、NPAT、ATM、C11orf65、KDELC2、EXPH5、DDX10、
SKCG-1、C11orf87、ZC3H12C、RDX、FDX1、ARHGAP20、C11orf53、C11orf92、C11orf93、MIR4491、POU2AF1、LOC100132078、LOC644277、BTG4、MIR34B、MIR34C、C11orf88、LAYN、SIK2、PPP2R1B、ALG9、FDXACB1、C11orf1、CRYAB、HSPB2、HSPB2-C11orf52、C11orf52、DIXDC1、DLAT、PIH1D2、C11orf57、TIMM8B、SDHD、IL18、TEX12、BCO2、PTS、C11orf34、NCAM1、LOC100288346、TTC12、ANKK1、DRD2、MIR4301、TMPRSS5、ZW10、CLDN25、USP28、HTR3B、HTR3A、ZBTB16、NNMT、C11orf71、RBM7、REXO2、NXPE1、NXPE4、NXPE2、CADM1、LOC283143、BUD13、ZNF259、APOA5、APOA4、APOC3、APOA1、SIK3、PAFAH1B2、SIDT2、LOC100652768、TAGLN、PCSK7、RNF214、BACE1、BACE1-AS、CEP164、DSCAML1、FXYD2、FXYD6-FXYD2、FXYD6、TMPRSS13、IL10RA、TMPRSS4-AS1、TMPRSS4、SCN4B、SCN2B、AMICA1、MPZL3、MPZL2、CD3E、CD3D、CD3G、UBE4A、LOC100131626、ATP5L、MGC13053、MLL、TTC36、TMEM25、IFT46、ARCN1、PHLDB1、TREH、DDX6、CXCR5、BCL9L、MIR4492、UPK2、FOXR1、CCDC84、RPL23AP64、RPS25、TRAPPC4、MIR3656、SLC37A4、HYOU1、VPS11、HMBS、H2AFX、DPAGT1、C2CD2L、HINFP、ABCG4、NLRX1、PDZD3、CCDC153、CBL、MCAM、RNF26、C1QTNF5、MFRP、USP2、LOC100499227、THY1、PVRL1、LOC100507077、TRIM29、OAF、POU2F3、LOC649133、TMEM136、ARHGEF12、GRIK4、TBCEL、TECTA、SC5DL、SORL1、LOC100507165、LOC100507145、MIR100HG、MIR125B1、BLID、MIRLET7A2、MIR100、UBASH3B、CRTAM、C11orf63、BSX、LOC341056、HSPA8、SNORD14E、SNORD14D、SNORD14C、CLMP、MIR4493、LOC100128242、GRAMD1B、SCN3B、ZNF202、OR6X1、OR6M1、TMEM225、OR8D4、OR4D5、OR6T1、OR10S1、OR10G4、OR10G9、OR10G8、OR10G7、VWA5A、OR8G2、OR8G1、OR8G5、OR8D1、OR8D2、OR8B2、OR8B3、OR8B4、OR8B8、OR8B12、OR8A1、PANX3、TBRG1、SIAE、SPA17、NRGN、VSIG2、ESAM、MSANTD2、LOC100130428、ROBO3、ROBO4、HEPACAM、HEPN1、CCDC15、SLC37A2、TMEM218、PKNOX2、FEZ1、MGC39545、EI24、STT3A、CHEK1、ACRV1、PATE1、PATE2、PATE3、PATE4、HYLS1、PUS3、DDX25、LOC338667、CDON、RPUSD4、FAM118B、SRPR、FOXRED1、TIRAP、DCPS、FLJ39051、ST3GAL4、KIRREL3、KIRREL3-AS2、MIR3167、KIRREL3-AS3、ETS1、FLI1、FLI1-AS1、KCNJ1、KCNJ5、C11orf45、TP53AIP1、ARHGAP32、BARX2、TMEM45B、NFRKB、PRDM10、LINC00167、APLP2、ST14、ZBTB44、LOC100996646、ADAMTS8、ADAMTS15、C11orf44、LOC100507431、SNX19、NTM、C11orf39、OPCML、SPATA19、LOC283174、MIR4697、LOC646543、IGSF9B、LOC100128239、JAM3、NCAPD3、VPS26B、THYN1、ACAD8、GLB1L3、GLB1L2、B3GAT1、LOC283177、LOC729305、LOC100507548、LOC100288778、FAM138D、IQSEC3、LOC574538、SLC6A12、SLC6A13、KDM5A、CCDC77、B4GALNT3、NINJ2、WNK1、RAD52、LOC100130219、ERC1、LOC100292680、FBXL14、WNT5B、MIR3649、ADIPOR2、
CACNA2D4、LRTM2、LOC100271702、DCP1B、CACNA1C、CACNA1C-AS4、CACNA1C-IT3、CACNA1C-AS1、LOC283440、FKBP4、ITFG2、NRIP2、LOC100507424、LOC100996378、FOXM1、RHNO1、TULP3、TEAD4、TSPAN9、PRMT8、LOC100129223、LOC100128816、EFCAB4B、PARP11、LOC100507511、CCND2、C12orf5、FGF23、FGF6、C12orf4、RAD51AP1、DYRK4、AKAP3、NDUFA9、GALNT8、KCNA6、KCNA1、LOC100507560、KCNA5、NTF3、ANO2、VWF、CD9、PLEKHG6、TNFRSF1A、SCNN1A、LTBR、CD27-AS1、CD27、TAPBPL、VAMP1、MRPL51、NCAPD2、SCARNA10、GAPDH、LOC100996356、IFFO1、NOP2、CHD4、LOC100127974、SCARNA11、LPAR5、ACRBP、ING4、ZNF384、PIANP、COPS7A、MLF2、PTMS、LAG3、CD4、GPR162、LEPREL2、GNB3、CDCA3、USP5、TPI1、SPSB2、RPL13P5、DSTNP2、LRRC23、ENO2、ATN1、RNU7-1、C12orf57、PTPN6、MIR200C、MIR141、PHB2、SCARNA12、EMG1、LPCAT3、C1 S、C1R、C1RL、C1RL-AS1、RBP5、CLSTN3、PEX5、ACSM4、CD163L1、CD163、APOBEC1、GDF3、DPPA3、CLEC4C、NANOGNB、NANOG、SLC2A14、SLC2A3、FOXJ2、C3AR1、NECAP1、CLEC4A、POU5F1P3、ZNF705A、FAM66C、FAM90A1、FAM86FP、LOC389634、CLEC6A、CLEC4D、CLEC4E、AICDA、MFAP5、RIMKLB、A2ML1、PHC1、M6PR、KLRG1、LINC00612、A2M-AS1、A2M、PZP、A2MP1、MIR1244-3、LOC100499405、LOC642846、LOC100653000、LOC728715、DDX12P、OVOS、KLRB1、LOC374443、CLEC2D、CLECL1、CD69、KLRF1、CLEC2B、KLRF2、CLEC2A、CLEC12A、CLEC1B、CLEC12B、CLEC9A、CLEC1A、CLEC7A、OLR1、TMEM52B、GABARAPL1、KLRD1、KLRC4-KLRK1、KLRK1、KLRC4、KLRC3、KLRC2、KLRC1、KLRAP1、MAGOHB、STYK1、CSDA、LOC100506226、TAS2R7、TAS2R8、TAS2R9、TAS2R10、PRH1-PRR4、PRR4、PRH1、TAS2R13、PRH2、TAS2R14、TAS2R50、TAS2R20、TAS2R19、TAS2R31、TAS2R46、TAS2R43、TAS2R30、TAS2R42、PRB3、PRB4、PRB1、PRB2、LOC338817、ETV6、BCL2L14、LOC100506248、LRP6、MANSC1、LOH12CR2、LOH12CR1、DUSP16、CREBL2、GPR19、CDKN1B、APOLD1、MIR613、DDX47、RPL13AP20、GPRC5A、MIR614、GPRC5D、HEBP1、LOC100506314、HTR7P1、KIAA1467、GSG1、EMP1、C12orf36、GRIN2B、ATF7IP、PLBD1、GUCY2C、HIST4H4、H2AFJ、WBP11、C12orf60、C12orf69、ART4、MGP、ERP27、ARHGDIB、PDE6H、RERG、PTPRO、EPS8、STRAP、DERA、SLC15A5、MGST1、LMO3、SKP1P2、MIR3974、RERGL、PIK3C2G、PLCZ1、CAPZA3、PLEKHA5、AEBP2、LOC100506393、PDE3A、SLCO1C1、SLCO1B3、SLCO1B7、SLCO1B1、SLCO1A2、IAPP、PYROXD1、RECQL、GOLT1B、C12orf39、GYS2、LDHB、KCNJ8、ABCC9、CMAS、ST8SIA1、KIAA0528、LOC100996472、ETNK1、SOX5、MIR920、LINC00477、BCAT1、C12orf77、LOC645177、LRMP、CASC1、LYRM5、KRAS、IFLTD1、MIR4302、LOC100506451、RASSF8、LOC100996477、BHLHE41、SSPN、ITPR2、ASUN、FGFR1OP2、TM7SF3、MED21、C12orf71、STK38L、ARNTL2、C12orf70、
PPFIBP1、REP15、MRPS35、MANSC4、KLHDC5、PTHLH、CCDC91、FAR2、LOC100506606、ERGIC2、LOC101055625、OVCH1、TMTC1、IPO8、CAPRIN2、LOC100287314、TSPAN11、DDX11-AS1、DDX11、FAM60A、FLJ13224、DENND5B、DENND5B-AS1、METTL20、AMN1、H3F3C、KIAA1551、BICD1、FGD4、DNM1L、YARS2、PKP2、SYT10、ALG10、ALG10B、CPNE8、KIF21A、ABCD2、C12orf40、SLC2A13、LRRK2、MUC19、CNTN1、PDZRN4、GXYLT1、YAF2、ZCRB1、PPHLN1、PRICKLE1、LOC100506684、ADAMTS20、PUS7L、IRAK4、TWF1、TMEM117、NELL2、DBX2、RACGAP1P、PLEKHA8P1、ANO6、LOC400027、ARID2、SCAF11、SLC38A1、SLC38A2、LOC100288798、SLC38A4、AMIGO2、MIR4698、PCED1B-AS1、PCED1B、MIR4494、RPAP3、ENDOU、RAPGEF3、SLC48A1、HDAC7、VDR、TMEM106C、COL2A1、SENP1、PFKM、ASB8、C12orf68、OR10AD1、H1FNT、ZNF641、LOC100505923、ANP32D、C12orf54、OR8S1、LALBA、KANSL2、SNORA34、SNORA2A、SNORA2B、CCNT1、LOC255411、ADCY6、MIR4701、LOC100506125、CACNB3、DDX23、RND1、CCDC65、FKBP11、ARF3、WNT10B、WNT1、DDN、PRKAG1、MLL2、RHEBL1、DHH、LMBR1L、TUBA1B、TUBA1A、LOC100293962、TUBA1C、PRPH、TROAP、C1QL4、DNAJC22、SPATS2、LOC100335030、KCNH3、MCRS1、FAM186B、PRPF40B、FMNL3、TMBIM6、NCKAP5L、BCDIN3D-AS1、BCDIN3D、FAIM2、LOC283332、AQP2、AQP5、AQP6、RACGAP1、ASIC1、SMARCD1、GPD1、COX14、CERS5、LIMA1、MIR1293、FAM186A、LARP4、DIP2B、ATF1、TMPRSS12、METTL7A、HIGD1C、SLC11A2、LETMD1、CSRNP2、TFCP2、POU6F1、DAZAP2、SMAGP、BIN2、CELA1、GALNT6、SLC4A8、SCN8A、FIGNL2、LOC728503、ANKRD33、ACVRL1、ACVR1B、GRASP、NR4A1、C12orf44、KRT80、LOC283403、LINC00592、KRT7、KRT81、KRT86、KRT83、KRT85、KRT84、KRT82、KRT75、KRT6B、KRT6C、KRT6A、KRT5、KRT71、KRT74、KRT72、KRT73、KRT2、KRT1、KRT77、KRT76、KRT3、KRT4、KRT79、KRT78、KRT8、KRT18、EIF4B、LOC283335、TENC1、SPRYD3、IGFBP6、SOAT2、CSAD、ZNF740、ITGB7、RARG、MFSD5、ESPL1、PFDN5、C12orf10、AAAS、SP7、SP1、AMHR2、PRR13、PCBP2、MAP3K12、TARBP2、NPFF、ATF7、LOC100652999、ATP5G2、CALCOCO1、HOXC-AS5、HOXC13、HOXC12、HOTAIR、HOXC11、HOXC10、MIR196A2、HOXC9、HOXC8、HOXC5、HOXC6、HOXC4、MIR615、FLJ12825、LOC100240735、LOC100240734、LOC400043、SMUG1、CBX5、MIR3198-2、HNRNPA1、NFE2、COPZ1、MIR148B、GPR84、ZNF385A、ITGA5、GTSF1、NCKAP1L、PDE1B、PPP1R1A、GLYCAM1、LACRT、DCD、MUCL1、TESPA1、NEUROD4、OR9K2、OR10A7、OR6C74、OR6C6、OR6C1、OR6C3、OR6C75、OR6C65、OR6C76、OR6C2、OR6C70、OR6C68、OR6C4、OR2AP1、OR10P1、METTL7B、ITGA7、BLOC1S1-RDH5、BLOC1S1、RDH5、CD63、GDF11、SARNP、ORMDL2、DNAJC14、TMEM198B、MMP19、WIBG、DGKA、PMEL、CDK2、RAB5B、SUOX、IKZF4、RPS26、ERBB3、
PA2G4、RPL41、ZC3H10、ESYT1、MYL6B、MYL6、SMARCC2、RNF41、NABP2、SLC39A5、ANKRD52、COQ10A、CS、CNPY2、PAN2、IL23A、STAT2、APOF、TIMELESS、MIP、SPRYD4、GLS2、RBMS2、BAZ2A、ATP5B、SNORD59B、SNORD59A、PTGES3、NACA、PRIM1、HSD17B6、SDR9C7、RDH16、GPR182、HBCBP、ZBTB39、TAC3、MYO1A、TMEM194A、NAB2、STAT6、LRP1、MIR1228、NXPH4、SHMT2、NDUFA4L2、STAC3、R3HDM2、INHBC、INHBE、GLI1、ARHGAP9、MARS、DDIT3、MIR616、MBD6、DCTN2、KIF5A、PIP4K2C、DTX3、ARHGEF25、SLC26A10、B4GALNT1、OS9、AGAP2、LOC100130776、TSPAN31、CDK4、MARCH9、CYP27B1、METTL1、METTL21B、TSFM、AVIL、CTDSP2、MIR26A2、LOC100506844、XRCC6BP1、LOC100506869、LRIG3、SLC16A7、FAM19A2、USP15、MON2、C12orf61、MIRLET7I、PPM1H、AVPR1A、DPY19L2、TMEM5、SRGAP1、C12orf66、C12orf56、XPOT、TBK1、RASSF3、MIR548Z、MIR548C、GNS、TBC1D30、FLJ41278、WIF1、LEMD3、MSRB3、LOC100507065、RPSAP52、HMGA2、LLPH、TMBIM4、IRAK3、HELB、GRIP1、CAND1、LOC100507175、DYRK2、IFNG、IL26、IL22、MDM1、LOC100507195、RAP1B、SNORA70G、LOC100507250、NUP107、SLC35E3、MDM2、CPM、CPSF6、MIR1279、LYZ、YEATS4、FRS2、MIR3913-1、MIR3913-2、CCT2、LRRC10、BEST3、RAB3IP、C12orf28、CNOT2、KCNMB4、PTPRB、LOC100507330、PTPRR、TSPAN8、LGR5、ZFC3H1、THAP2、TMEM19、RAB21、TBC1D15、MRS2P2、TPH2、TRHDE-AS1、TRHDE、LOC100507363、LOC100507377、ATXN7L3B、KCNC2、CAPS2、GLIPR1L1、GLIPR1L2、GLIPR1、KRR1、PHLDA1、NAP1L1、BBS10、OSBPL8、ZDHHC17、CSRP2、E2F7、LOC100507484、NAV3、LOC100507498、SYT1、MIR1252、PAWR、PPP1R12A、OTOGL、PTPRQ、MYF6、MYF5、LIN7A、MIR617、MIR618、ACSS3、MIR4699、PPFIA2、CCDC59、METTL25、TMTC2、SLC6A15、TSPAN19、LRRIQ1、ALX1、RASSF9、NTS、MGAT4C、LOC100507559、MKRN9P、C12orf50、C12orf29、CEP290、TMTC3、KITLG、LOC728084、DUSP6、POC1B、POC1B-GALNT4、GALNT4、ATP2B1、LOC338758、LOC100507594、LINC00615、CCER1、EPYC、KERA、LUM、DCN、LOC256021、BTG1、CLLU1OS、CLLU1、C12orf74、PLEKHG7、EEA1、LOC643339、NUDT4、UBE2N、MRPL42、SOCS2-AS1、SOCS2、CRADD、PLXNC1、CCDC41、LOC144486、MIR5700、TMCC3、MIR492、KRT19P2、NDUFA12、NR2C1、FGD6、VEZT、MIR331、MIR3685、METAP2、USP44、NTN4、LOC100505645、SNRPF、CCDC38、AMDHD1、HAL、LTA4H、ELK3、CDK17、C12orf55、LOC100996254、NEDD1、RMST、MIR1251、MIR135A2、RNU6-36、MIR4495、MIR4303、SLC9A7P1、LOC643770、TMPO-AS1、TMPO、SLC25A3、SNORA53、IKBIP、APAF1、ANKS1B、FAM71C、UHRF1BP1L、GOLGA2P5、MIR1827、ACTR6、DEPDC4、SCYL2、SLC17A8、NR1H4、GAS2L3、ANO4、SLC5A8、UTP20、ARL1、SPIC、MYBPC1、CHPT1、SYCP3、GNPTAB、DRAM1、CCDC53、NUP37、
PARPBP、PMCH、IGF1、LINC00485、PAH、ASCL1、C12orf42、STAB2、NT5DC3、GNN、HSP90B1、MIR3652、C12orf73、TDG、GLT8D2、HCFC2、NFYB、TXNRD1、EID3、CHST11、IGANRP、MIR3922、SLC41A2、C12orf45、ALDH1L2、KIAA1033、APPL2、C12orf75、NUAK1、CKAP4、TCP11L2、POLR3B、LOC100287944、RFX4、LOC100505978、RIC8B、C12orf23、MTERFD3、CRY1、BTBD11、PWP1、PRDM4、ASCL4、LOC728739、WSCD2、CMKLR1、FICD、SART3、ISCU、TMEM119、SELPLG、MIR4496、CORO1C、SSH1、MIR619、DAO、SVOP、USP30-AS1、USP30、ALKBH2、UNG、ACACB、FOXN4、MYO1H、KCTD10、UBE3B、MMAB、MVK、FAM222A、FAM222A-AS1、TRPV4、MIR4497、GLTP、TCHP、GIT2、ANKRD13A、C12orf76、IFT81、ATP2A2、ANAPC7、ARPC3、GPN3、FAM216A、VPS29、RAD9B、PPTC7、TCTN1、HVCN1、PPP1CC、CCDC63、MYL2、LOC100131138、CUX2、FAM109A、SH2B3、ATXN2、BRAP、ACAD10、ALDH2、MAPKAPK5-AS1、MAPKAPK5、ADAM1A、TMEM116、ERP29、NAA25、MIR3657、TRAFD1、HECTD4、RPL6、PTPN11、MIR1302-1、RPH3A、OAS1、OAS3、OAS2、DTX1、RASAL1、CCDC42B、DDX54、C12orf52、IQCD、TPCN1、SLC24A6、PLBD2、SDS、SDSL、LHX5、LOC100506465、RBM19、TBX5、TBX5-AS1、TBX3、MED13L、MIR620、MIR4472-2、LINC00173、MAP1LC3B2、C12orf49、RNFT2、HRK、FBXW8、TESC、FBXO21、NOS1、KSR2、RFC5、WSB2、LOC100128895、VSIG10、PEBP1、TAOK3、SUDS3、SRRM4、HSPB8、LOC144742、CCDC60、TMEM233、PRKAB1、CIT、MIR1178、CCDC64、RAB35、GCN1L1、MIR4498、RPLP0、PXN-AS1、PXN、LOC100996317、RNU4-2、RNU4-1、SIRT4、PLA2G1B、MSI1、COX6A1、TRIAP1、GATC、SRSF9、DYNLL1、LOC100506668、COQ5、RNF10、POP5、CABP1、MLEC、UNC119B、MIR4700、ACADS、SPPL3、HNF1A-AS1、HNF1A、C12orf43、OASL、P2RX7、P2RX4、CAMKK2、ANAPC5、RNF34、KDM2B、ORAI1、MORN3、TMEM120B、RHOF、LOC338799、SETD1B、HPD、PSMD9、WDR66、BCL7A、LOC100506691、MLXIP、LRRC43、IL31、B3GNT4、DIABLO、VPS33A、CLIP1、LOC100507066、ZCCHC8、RSRC2、KNTC1、HCAR2、HCAR3、HCAR1、DENR、CCDC62、HIP1R、VPS37B、ABCB9、OGFOD2、ARL6IP4、PITPNM2、MIR4304、LOC100507091、MPHOSPH9、C12orf65、CDK2AP1、SBNO1、LOC100293704、SETD8、RILPL2、SNRNP35、RILPL1、MIR3908、TMED2、DDX55、EIF2B1、GTF2H3、TCTN2、ATP6V0A2、DNAH10、CCDC92、ZNF664、ZNF664-FAM101A、FAM101A、NCOR2、SCARB1、UBC、MIR5188、DHX37、BRI3BP、AACS、TMEM132B、LOC400084、LOC100128554、LOC100996671、LOC387895、LOC100507206、LOC440117、FLJ37505、LINC00507、MIR4419B、TMEM132C、MIR3612、SLC15A4、LOC100128276、GLT1D1、TMEM132D、LOC100190940、FLJ31485、FZD10、PIWIL1、RIMBP2、STX2、RAN、GPR133、LOC100128840、LOC116437、LOC100128002、LOC338797、LOC100996701、SFSWAP、MMP17、ULK1、PUS1、EP400、SNORA49、EP400NL、DDX51、
NOC4L、LOC100996246、GALNT9、LOC100130238、LOC100506978、FBRSL1、LOC100996573、LRCOL1、P2RX2、POLE、PXMP2、PGAM5、ANKLE2、GOLGA3、CHFR、ZNF605、ZNF26、ZNF84、ZNF140、ZNF10、ZNF268、ANHX、ANKRD20A9P、RNU6-55、RNU6-76、LOC100652856、LINC00442、RNU6-52、TUBA3C、ANKRD26P3、LINC00421、TPTE2、MPHOSPH8、PSPC1、ZMYM5、ZMYM2、GJA3、GJB2、GJB6、CRYL1、MIR4499、IFT88、IL17D、N6AMT2、XPO4、LATS2、SAP18、SKA3、MRP63、MIPEPP3、LINC00539、ZDHHC20、EFHA1、RNU6-59、FGF9、LINC00424、LINC00540、BASP1P1、SGCG、RNU6-58、SACS、SACS-AS1、LINC00327、TNFRSF19、MIPEP、C1QTNF9B-AS1、C1QTNF9B、ANKRD20A19P、SPATA13、MIR2276、SPATA13-AS1、C1QTNF9、PARP4、TPTE2P6、ATP12A、RNF17、CENPJ、TPTE2P1、LOC100996470、PABPC3、FAM123A、LOC100996347、MTMR6、NUPL1、ATP8A2、RNU6-78、SHISA2、RNF6、CDK8、WASF3、GPR12、USP12、RPL21、SNORD102、SNORA27、RASL11A、GTF3A、MTIF3、RNU6-63、LNX2、POLR1D、LOC100506997、GSX1、PDX1、ATP5EP2、LINC00543、CDX2、PRHOXNB、FLT3、PAN3-AS1、PAN3、RNU6-82、FLT1、POMP、SLC46A3、RNU6-53、MTUS2、MTUS2-AS1、SLC7A1、UBL3、LINC00297、LINC00544、KATNAL1、RNU6-64、LINC00427、LINC00426、HMGB1、USPL1、ALOX5AP、LINC00398、LINC00545、TEX26-AS1、MEDAG、TEX26、HSPH1、B3GALTL、RXFP2、EEF1DP3、FRY-AS1、FRY、ZAR1L、BRCA2、N4BP2L1、N4BP2L2、MINOS1P1、N4BP2L2-IT2、PDS5B、LINC00423、KL、STARD13、STARD13-AS2、RFC3、LINC00457、NBEA、MAB21L1、LINC00445、DCLK1、SOHLH2、CCDC169-SOHLH2、CCDC169、RNU6-71、SPG20、SPG20OS、CCNA1、SERTM1、RFXAP、SMAD9、ALG5、EXOSC8、FAM48A、CSNK1A1L、LINC00547、POSTN、TRPC4、LINC00571、UFM1、LINC00366、FREM2、RNU6-56、STOML3、PROSER1、NHLRC3、LHFP、COG6、MIR4305、LINC00332、LINC00548、LINC00598、FOXO1、MIR320D1、MRPS31、SLC25A15、TPTE2P5、MIR621、SUGT1P3、ELF1、WBP4、MIR3168、KBTBD6、KBTBD7、MTRF1、NAA16、RNU6-57、OR7E37P、RGCC、VWA8、MIR5006、VWA8-AS1、DGKH、AKAP11、TNFSF11、FAM216B、EPSTI1、DNAJC15、ENOX1、CCDC122、LACC1、LINC00284、SMIM2、SMIM2-IT1、SERP2、TSC22D1、TSC22D1-AS1、LINC00330、NUFIP1、KIAA1704、LOC100996395、GTF2F2、RNU6-69、KCTD4、TPT1、SNORA31、TPT1-AS1、SLC25A30、SLC25A30-AS1、COG3、FAM194B、SPERT、SIAH3、ZC3H13、CPB2-AS1、CPB2、LCP1、LINC00563、KIAA0226L、RNU6-68、LOC731932、LRCH1、ESD、HTR2A、SUCLA2、NUDT15、MED4、MED4-AS1、ITM2B、LINC00441、RB1、LPAR6、RCBTB2、LOC100996412、LOC100996416、LINC00462、CYSLTR2、FNDC3A、MLNR、CDADC1、CAB39L、SETDB2、PHF11、RCBTB1、ARL11、EBPL、KPNA3、CTAGE10P、SPRYD7、DLEU2、MIR3613、TRIM13、KCNRG、MIR16-1、MIR15A、DLEU1、FLJ31945、ST13P4、DLEU7、DLEU7-AS1、RNASEH2B-AS1、
RNASEH2B、GUCY1B2、LINC00371、FAM124A、SERPINE3、MIR5693、INTS6、INTS6-AS1、MIR4703、WDFY2、DHRS12、LINC00282、CCDC70、ATP7B、ALG11、UTP14C、LOC100506859、NEK5、NEK3、MRPS31P5、TPTE2P2、THSD1、VPS36、CKAP2、TPTE2P3、HNRNPA1L2、SUGT1、LECT1、MIR759、PCDH8、OLFM4、LINC00558、LINC00458、MIR1297、MIR5007、PRR20A、PRR20B、PRR20C、PRR20D、PRR20E、PCDH17、DIAPH3、DIAPH3-AS1、DIAPH3-AS2、TDRD3、MIR3169、PCDH20、OR7E156P、LOC647264、RNU6-81、MIR548X2、MIR4704、PCDH9、PCDH9-AS2、PCDH9-AS3、LINC00550、KLHL1、ATXN8OS、LINC00348、DACH1、MZT1、BORA、DIS3、PIBF1、RNU6-79、KLF5、RNU6-66、KLF12、LINC00402、LOC100288208、LINC00381、LINC00347、CTAGE11P、TBC1D4、COMMD6、UCHL3、LMO7、C13orf45、KCTD12、BTF3P11、IRG1、CLN5、FBXL3、MYCBP2、MYCBP2-AS1、SCEL、LOC100129307、SLAIN1、MIR3665、LOC100505518、EDNRB、LINC00439、LINC00446、POU4F1-AS1、POU4F1、RNF219、LINC00331、RBM26、RBM26-AS1、NDFIP2-AS1、NDFIP2、SPRY2、RNU6-67、SLITRK1、LINC00333、LINC00351、RNU6-72、SLITRK6、MIR4500HG、MIR4500、SLITRK5、LINC00433、LINC00353、LINC00559、MIR622、RNU6-75、LINC00410、LINC00379、MIR17HG、MIR17、MIR18A、MIR19A、MIR20A、MIR19B1、MIR92A1、GPC5、MIR548AS、GPC5-AS1、GPC6、GPC6-AS2、DCT、TGDS、GPR180、SOX21、ABCC4、CLDN10、CLDN10-AS1、DZIP1、DNAJC3、UGGT2、HS6ST3、MIR4501、LINC00359、OXGR1、MBNL2、RAP2A、IPO5、FARP1、RNF113B、MIR3170、STK24、SLC15A1、DOCK9、RNU6-83、UBAC2-AS1、UBAC2、GPR18、GPR183、FKSG29、MIR623、TM9SF2、CLYBL、MIR4306、ZIC5、ZIC2、PCCA、PCCA-AS1、GGACT、LOC100507654、TMTC4、LOC100996276、NALCN-AS1、NALCN、ITGBL1、FGF14、MIR2681、MIR4705、FGF14-IT1、FGF14-AS2、TPP2、METTL21C、CCDC168、TEX30、KDELC1、BIVM、BIVM-ERCC5、ERCC5、METTL21EP、SLC10A2、DAOA-AS1、DAOA、LINC00343、LINC00460、EFNB2、ARGLU1、LINC00551、LINC00443、FAM155A、MIR1267、LIG4、ABHD13、TNFSF13B、MYO16、MYO16-AS1、IRS2、COL4A1、COL4A2、COL4A2-AS2、COL4A2-AS1、RAB20、CARKD、CARS2、ING1、LINC00346、ANKRD10、ANKRD10-IT1、LOC100996267、ARHGEF7、TEX29、SOX1、LINC00403、SPACA7、TUBGCP3、C13orf35、ATP11A、LOC100506063、MCF2L-AS1、MCF2L、F7、F10、PROZ、PCID2、CUL4A、LAMP1、GRTP1、ADPRHL1、DCUN1D2、TMCO3、TFDP1、ATP4B、GRK1、LINC00552、FAM70B、GAS6-AS1、GAS6、LOC100506394、LINC00452、LINC00565、RASA3、CDC16、MIR548AR、MIR4502、UPF3A、CHAMP1、OR11H12、LOC642426、POTEG、LOC100506303、FLJ39632、POTEM、OR11H2、OR4Q3、OR4M1、OR4N2、OR4K2、OR4K5、OR4K1、OR4K15、OR4K14、OR4K13、OR4L1、OR4K17、OR4N5、OR11G2、OR11H6、OR11H4、TTC5、CCNB1IP1、SNORD126、
RPPH1、PARP2、TEP1、KLHL33、OSGEP、APEX1、TMEM55B、PNP、RNASE10、RNASE9、RNASE11、RNASE12、OR6S1、ANG、RNASE4、EDDM3A、EDDM3B、RNASE6、RNASE1、LOC100507513、RNASE3、ECRP、RNASE2、METTL17、SLC39A2、NDRG2、TPPP2、RNASE13、RNASE7、RNASE8、ARHGEF40、ZNF219、TMEM253、OR5AU1、LINC00641、HNRNPC、RPGRIP1、SUPT16H、CHD8、SNORD9、SNORD8、RAB2B、TOX4、METTL3、SALL2、OR10G3、OR10G2、OR4E2、DAD1、ABHD4、OXA1L、SLC7A7、MRPL52、MMP14、LRP10、REM2、RBM23、PRMT5-AS1、PRMT5、HAUS4、MIR4707、AJUBA、C14orf93、PSMB5、PSMB11、CDH24、ACIN1、C14orf119、LOC100128908、CEBPE、SLC7A8、C14orf164、HOMEZ、PPP1R3E、BCL2L2-PABPN1、BCL2L2、PABPN1、SLC22A17、EFS、IL25、CMTM5、MYH6、MIR208A、MYH7、MIR208B、NGDN、THTPA、ZFHX2、AP1G2、JPH4、DHRS2、DHRS4-AS1、DHRS4、DHRS4L2、DHRS4L1、LRRC16B、CPNE6、NRL、PCK2、DCAF11、FITM1、PSME1、EMC9、PSME2、RNF31、IRF9、REC8、IPO4、TM9SF1、TSSK4、CHMP4A、MDP1、NEDD8-MDP1、NEDD8、GMPR2、TINF2、TGM1、RABGGTA、DHRS1、NOP9、CIDEB、LTB4R2、LTB4R、ADCY4、RIPK3、NFATC4、NYNRIN、CBLN3、KHNYN、SDR39U1、CMA1、CTSG、GZMH、GZMB、STXBP6、NOVA1、MIR4307、LOC728755、LINC00645、FOXG1、C14orf23、LOC100506004、LOC100996589、PRKD1、G2E3、SCFD1、COCH、LOC100506071、STRN3、MIR624、AP4S1、HECTD1、HEATR5A、DTD2、GPR33、NUBPL、LOC100506110、ARHGAP5-AS1、ARHGAP5、AKAP6、NPAS3、EGLN3、SPTSSA、EAPP、RNU1-7、RNU1-8、SNX6、CFL2、BAZ1A、IGBP1P1、LOC100506157、SRP54、FAM177A1、PPP2R3C、KIAA0391、PSMA6、NFKBIA、INSM2、RALGAPA1、BRMS1L、PTCSC3、MBIP、SFTA3、NKX2-1、NKX2-1-AS1、NKX2-8、PAX9、SLC25A21、MIR4503、LOC100129794、MIPOL1、FOXA1、TTC6、SSTR1、CLEC14A、LINC00639、SEC23A、GEMIN2、TRAPPC6B、PNN、MIA2、CTAGE5、LOC100288846、FBXO33、LRFN5、FSCB、C14orf28、KLHL28、FAM179B、LOC100996613、PRPF39、SNORD127、FKBP3、FANCM、MIS18BP1、RPL10L、MDGA2、MIR548Y、LINC00648、RPS29、RN7SL1、LRR1、RPL36AL、MGAT2、DNAAF2、POLE2、KLHDC1、KLHDC2、NEMF、RN7SL2、ARF6、C14orf182、LOC100506499、C14orf183、METTL21D、SOS2、L2HGDH、MIR4504、ATP5S、CDKL1、MAP4K5、ATL1、SAV1、NIN、ABHD12B、PYGL、TRIM9、TMX1、LINC00640、FRMD6-AS2、FRMD6、FRMD6-AS1、GNG2、C14orf166、NID2、PTGDR、PTGER2、TXNDC16、GPR137C、ERO1L、PSMC6、STYX、GNPNAT1、FERMT2、DDHD1、MIR5580、BMP4、CDKN3、CNIH、GMFB、CGRRF1、SAMD4A、GCH1、MIR4308、WDHD1、SOCS4、MAPK1IP1L、LGALS3、DLGAP5、FBXO34、ATG14、TBPL2、KTN1-AS1、KTN1、RPL13AP3、LINC00520、PELI2、C14orf101、OTX2、OTX2-AS1、EXOC5、AP5M1、NAA30、C14orf105、SLC35F4、C14orf37、ACTR10、PSMA3、FLJ31306、
ARID4A、TOMM20L、TIMM9、KIAA0586、DACT1、DAAM1、GPR135、L3HYPDH、JKAMP、CCDC175、RTN1、MIR5586、LRRC9、PCNXL4、DHRS7、PPM1A、C14orf39、SIX6、SIX1、SIX4、MNAT1、TRMT5、SLC38A6、TMEM30B、PRKCH、FLJ22447、HIF1A、HIF1A-AS2、SNAPC1、SYT16、LINC00643、KCNH5、RHOJ、GPHB5、PPP2R5E、WDR89、SGPP1、SYNE2、MIR548H1、ESR2、TEX21P、MTHFD1、AKAP5、ZBTB25、ZBTB1、HSPA2、PPP1R36、PLEKHG3、SPTB、CHURC1、CHURC1-FNTB、GPX2、RAB15、FNTB、MAX、MIR4706、LOC100506321、MIR4708、FUT8、FUT8-AS1、MIR625、LINC00238、GPHN、FAM71D、MPP5、ATP6V1D、EIF2S1、PLEK2、MIR5694、TMEM229B、PLEKHH1、PIGH、ARG2、VTI1B、RDH11、RDH12、ZFYVE26、RAD51B、LOC100996664、ZFP36L1、ACTN1、DCAF5、EXD2、GALNTL1、ERH、SLC39A9、PLEKHD1、CCDC177、KIAA0247、LOC100289511、SRSF5、SLC10A1、LOC100506358、SMOC1、SLC8A3、ADAM21P1、SYNJ2BP-COX16、COX16、SYNJ2BP、ADAM21、ADAM20P1、ADAM20、MED6、TTC9、MAP3K9、PCNX、SNORD56B、LOC145474、SIPA1L1、RGS6、DPF3、DCAF4、ZFYVE1、RBM25、PSEN1、PAPLN、NUMB、HEATR4、C14orf169、ACOT1、ACOT2、ACOT4、ACOT6、DNAL1、PNMA1、ELMSAN1、MIR4505、LOC100506476、LOC100506498、PTGR2、ZNF410、FAM161B、COQ6、ENTPD5、CCDC176、ALDH6A1、LIN52、VSX2、ABCD4、VRTN、SYNDIG1L、NPC2、MIR4709、ISCA2、LTBP2、KIAA0317、FCF1、YLPM1、PROX2、DLST、RPS6KL1、PGF、EIF2B2、MLH3、ACYP1、ZC2HC1C、NEK9、TMED10、FOS、LOC731223、JDP2、BATF、FLVCR2、C14orf1、TTLL5、TGFB3、IFT43、GPATCH2L、ESRRB、VASH1、ANGEL1、C14orf166B、IRF2BPL、KIAA1737、ZDHHC22、TMEM63C、NGB、MIR1260A、POMT2、GSTZ1、TMED8、SAMD15、NOXRED1、VIPAS39、AHSA1、ISM2、SPTLC2、ALKBH1、SLIRP、SNW1、C14orf178、ADCK1、NRXN3、DIO2、DIO2-AS1、CEP128、TSHR、GTF2A1、SNORA79、STON2、LOC100506700、SEL1L、LOC100996280、FLRT2、LOC100506718、LOC283585、GALC、GPR65、LOC283587、KCNK10、SPATA7、PTPN21、ZC3H14、EML5、TTC8、FOXN3、LOC100128075、FOXN3-AS1、FOXN3-AS2、LOC100506792、EFCAB11、TDP1、KCNK13、PSMC1、NRDE2、CALM1、LINC00642、TTC7B、LOC283588、RPS6KA5、C14orf159、SNORA11B、GPR68、CCDC88C、SMEK1、CATSPERB、TC2N、FBLN5、TRIP11、ATXN3、NDUFB1、CPSF2、SLC24A4、RIN3、LGMN、GOLGA5、CHGA、ITPK1、ITPK1-AS1、MOAP1、TMEM251、C14orf142、UBR7、BTBD7、UNC79、COX8C、PRIMA1、FAM181A-AS1、FAM181A、ASB2、MIR4506、LINC00521、OTUB2、DDX24、IFI27L1、IFI27、IFI27L2、PPP4R4、SERPINA10、SERPINA6、SERPINA1、SERPINA11、SERPINA9、SERPINA12、SERPINA4、SERPINA5、SERPINA3、SERPINA13P、GSC、DICER1、MIR3173、DICER1-AS1、CLMN、LINC00341、SYNE3、LOC100506972、SNHG10、SCARNA13、GLRX5、LOC100506999、TCL6、TCL1B、TCL1A、
LOC100133207、LINC00617、C14orf132、BDKRB2、BDKRB1、LOC100130815、ATG2B、GSKIP、AK7、PAPOLA、VRK1、LOC100129345、C14orf64、C14orf177、BCL11B、SETD3、CCNK、CCDC85C、LOC100507108、HHIPL1、CYP46A1、EML1、EVL、MIR151B、MIR342、DEGS2、YY1、SLC25A29、MIR345、SLC25A47、WARS、WDR25、BEGAIN、LINC00523、DLK1、MIR2392、MEG3、MIR770、MIR493、MIR337、MIR665、RTL1、MIR431、MIR433、MIR127、MIR432、MIR136、LOC100288160、MEG8、SNORD112、MIR370、SNORD113-1、SNORD113-2、SNORD113-3、SNORD113-4、SNORD113-5、SNORD113-6、SNORD113-7、SNORD113-8、SNORD113-9、LOC100507242、SNORD114-1、SNORD114-2、SNORD114-3、SNORD114-4、SNORD114-5、SNORD114-6、SNORD114-7、SNORD114-8、SNORD114-9、SNORD114-10、SNORD114-11、SNORD114-12、SNORD114-13、SNORD114-14、SNORD114-15、SNORD114-16、SNORD114-17、SNORD114-18、SNORD114-19、SNORD114-20、SNORD114-21、SNORD114-22、SNORD114-23、SNORD114-24、SNORD114-25、SNORD114-26、SNORD114-27、SNORD114-28、SNORD114-29、SNORD114-30、SNORD114-31、MIR379、MIR411、MIR299、MIR380、MIR1197、MIR323A、MIR758、MIR329-1、MIR329-2、MIR494、MIR1193、MIR543、MIR495、MIR376C、MIR376A2、MIR654、MIR376B、MIR376A1、MIR300、MIR1185-1、MIR1185-2、MIR381、MIR487B、MIR539、MIR889、MIR544A、MIR655、MIR487A、MIR382、MIR134、MIR668、MIR485、MIR323B、MIR154、MIR496、MIR377、MIR541、MIR409、MIR412、MIR369、MIR410、MIR656、MEG9、LOC100507277、DIO3OS、MIR1247、DIO3、LINC00239、PPP2R5C、LOC100653021、DYNC1H1、HSP90AA1、WDR20、MOK、ZNF839、CINP、TECPR2、ANKRD9、MIR4309、RCOR1、TRAF3、AMN、CDC42BPB、EXOC3L4、TNFAIP2、LINC00605、EIF5、SNORA28、MARK3、CKB、TRMT61A、BAG5、APOPT1、KLC1、XRCC3、ZFYVE21、PPP1R13B、LINC00637、C14orf2、TDRD9、RD3L、ASPG、MIR203、MIR3545、KIF26A、C14orf180、LOC100288144、TMEM179、MIR4710、INF2、ADSSL1、SIVA1、AKT1、ZBTB42、LINC00638、KIAA0284、PLD4、AHNAK2、C14orf79、CDCA4、GPR132、JAG2、NUDT14、BRF1、BTBD6、PACS2、TEX22、LOC100507437、MTA1、LOC100128343、CRIP2、CRIP1、C14orf80、TMEM121、MIR4507、KIAA0125、ADAM6、LINC00226、LINC00221、CHEK2P2、HERC2P3、GOLGA6L6、GOLGA8CP、NBEAP1、MIR3118-4、MIR5701-1、LOC348120、LOC646214、CXADRP2、MIR3118-6、NF1P2、MIR5701-2、LOC727924、OR4M2、OR4N4、OR4N3P、MIR1268A、REREP3、MIR4509-1、GOLGA8DP、GOLGA6L1、TUBGCP5、CYFIP1、NIPA2、NIPA1、LOC283683、WHAMMP3、GOLGA8I、HERC2P2、HERC2P7、GOLGA8EP、LOC100996599、LOC440243、GOLGA8S、GOLGA6L2、MIR4508、MKRN3、MAGEL2、NDN、PWRN2、PWRN1、NPAP1、SNRPN、SNURF、SNORD107、PAR-SN、PAR5、SNORD64、SNORD108、LOC100506948、
SNORD109A、SNORD116-1、SNORD116-2、SNORD116-3、SNORD116-4、SNORD116-5、SNORD116-6、SNORD116-7、SNORD116-8、SNORD116-9、SNORD116-10、SNORD116-11、SNORD116-12、SNORD116-13、SNORD116-14、SNORD116-15、SNORD116-16、SNORD116-17、SNORD116-18、SNORD116-19、SNORD116-20、SNORD116-21、SNORD116-22、SNORD116-23、SNORD116-24、SNORD116-25、SNORD116-26、SNORD116-27、SNORD116-28、SNORD116-29、IPW、PAR1、SNORD115-1、SNORD115-2、SNORD115-3、SNORD115-4、SNORD115-5、SNORD115-6、SNORD115-7、SNORD115-8、SNORD115-9、SNORD115-10、SNORD115-11、SNORD115-12、SNORD115-13、SNORD115-14、SNORD115-15、SNORD115-16、SNORD115-17、SNORD115-18、SNORD115-19、SNORD115-20、SNORD115-21、SNORD115-22、PAR4、SNORD115-23、SNORD115-24、SNORD115-25、SNORD115-26、SNORD115-27、SNORD115-28、SNORD115-29、SNORD115-30、SNORD115-31、SNORD115-32、SNORD115-33、SNORD115-34、SNORD115-35、SNORD115-36、SNORD115-37、SNORD115-38、SNORD115-39、SNORD115-40、SNORD115-41、SNORD115-42、SNORD115-43、SNORD115-44、SNORD115-45、SNORD115-47、SNORD115-48、SNORD109B、UBE3A、ATP10A、MIR4715、LOC100128714、LOC503519、GABRB3、GABRA5、GABRG3、OCA2、HERC2、LOC100996625、LOC645202、GOLGA8F、MIR4509-2、MIR4509-3、GOLGA8G、LOC100132202、LOC100996644、HERC2P9、WHAMMP2、LOC100289656、LOC646278、GOLGA6L7P、APBA2、FAM189A1、NDNL2、LOC100130111、TJP1、GOLGA8J、ULK4P3、GOLGA8T、DKFZP434L187、CHRFAM7A、LOC100996413、ULK4P2、GOLGA8H、ARHGAP11B、LOC100288637、HERC2P10、FAN1、MTMR10、TRPM1、MIR211、LOC283710、KLF13、OTUD7A、CHRNA7、LOC100996675、GOLGA8K、ULK4P1、GOLGA8O、WHAMMP1、LOC100996255、ARHGAP11A、SCG5、GREM1、FMN1、TMCO5B、RYR3、AVEN、CHRM5、EMC7、PGBD4、KATNBL1、EMC4、SLC12A6、NOP10、C15orf55、LPCAT4、GOLGA8A、MIR1233-1、GOLGA8B、MIR1233-2、GJD2、ACTC1、AQR、ZNF770、ANP32AP1、ATPBD4、MIR3942、ATPBD4-AS1、MIR4510、LOC100507480、C15orf41、CSNK1A1P1、LOC145845、MEIS2、TMCO5A、SPRED1、FAM98B、RASGRP1、C15orf53、C15orf54、THBS1、FSIP1、GPR176、LOC100505534、EIF2AK4、SRP14、LOC100131089、BMF、BUB1B、PAK6、C15orf56、ANKRD63、PLCB2、C15orf52、PHGR1、DISP2、C15orf23、IVD、BAHD1、CHST14、MRPL42P5、C15orf57、RPUSD2、CASC5、LOC100505648、RAD51、FAM82A2、GCHFR、DNAJC17、C15orf62、ZFYVE19、PPP1R14D、SPINT1、RHOV、VPS18、DLL4、CHAC1、INO80、EXD1、CHP1、OIP5-AS1、OIP5、NUSAP1、NDUFAF1、RTF1、ITPKA、LTK、RPAP1、TYRO3、MGA、MIR626、MAPKBP1、JMJD7、JMJD7-PLA2G4B、PLA2G4B、SPTBN5、MIR4310、LOC100289090、EHD4、PLA2G4E、PLA2G4D、PLA2G4F、VPS39、MIR627、TMEM87A、
GANC、CAPN3、ZFP106、SNAP23、LRRC57、HAUS2、STARD9、CDAN1、TTBK2、UBR1、TMEM62、CCNDBP1、EPB42、TGM5、TGM7、LCMT2、ADAL、ZSCAN29、TUBGCP4、TP53BP1、MAP1A、PPIP5K1、CKMT1B、STRC、CATSPER2、CKMT1A、CATSPER2P1、PDIA3、ELL3、SERF2、SERF2-C15ORF63、MIR1282、SERINC4、HYPK、MFAP1、WDR76、FRMD5、PIN4P1、CASC4、CTDSPL2、LOC645212、EIF3J、SPG11、PATL2、B2M、TRIM69、C15orf43、SORD、DUOX2、DUOXA2、DUOXA1、DUOX1、SHF、SLC28A2、GATM、GATM-AS1、SPATA5L1、C15orf48、MIR147B、SLC30A4、HMGN2P46、BLOC1S6、SQRDL、SEMA6D、SLC24A5、MYEF2、CTXN2、SLC12A1、DUT、FBN1、LOC100506059、CEP152、SHC4、EID1、SECISBP2L、COPS2、GALK2、NDUFAF4P1、MIR4716、FAM227B、FGF7、DTWD1、ATP8B4、SLC27A2、HDC、GABPB1、FLJ10038、GABPB1-AS1、MIR4712、USP8、USP50、TRPM7、SPPL2A、AP4E1、DCAF13P3、TNFAIP8L3、CYP19A1、MIR4713、LOC100652954、LOC100996299、GLDN、DMXL2、SCG3、LYSMD2、TMOD2、TMOD3、LEO1、MAPK6、BCL2L10、GNB5、LOC100129973、MYO5C、MIR1266、MYO5A、ARPP19、FAM214A、ONECUT1、WDR72、UNC13C、RSL24D1、RAB27A、PIGB、DYX1C1-CCPG1、CCPG1、MIR628、FLJ27352、DYX1C1、PYGO1、PRTG、NEDD4、RFX7、TEX9、MNS1、ZNF280D、LOC145783、TCF12、LOC283663、CGNL1、GCOM1、MYZAP、POLR2M、ALDH1A2、AQP9、LIPC、ADAM10、HSP90AB4P、FAM63B、SLTM、RNF111、CCNB2、MYO1E、MIR2116、LDHAL6B、FAM81A、GCNT3、GTF2A2、BNIP2、FOXB1、ANXA2、NARG2、RORA、LOC100506530、VPS13C、C2CD4A、C2CD4B、MGC15885、TLN2、MIR190A、TPM1、LOC100128979、LACTB、RPS27L、RAB8B、APH1B、CA12、USP3、LOC100130855、FBXL22、HERC1、MIR422A、DAPK2、FAM96A、SNX1、SNX22、PPIB、CSNK1G1、KIAA0101、TRIP4、ZNF609、OAZ2、RBPMS2、MIR1272、PIF1、PLEKHO2、ANKDD1A、SPG21、MTFMT、SLC51B、RASL12、KBTBD13、UBAP1L、PDCD7、CLPX、CILP、PARP16、RNU5A-1、RNU5B-1、IGDCC3、IGDCC4、DPP8、PTPLAD1、RNU6-19、VWA9、SLC24A1、DENND4A、MIR4511、RAB11A、MEGF11、MIR4311、DIS3L、TIPIN、SCARNA14、MAP2K1、SNAPC5、MIR4512、RPL4、SNORD18C、SNORD18B、SNORD16、SNORD18A、ZWILCH、LCTL、SMAD6、SMAD3、AAGAB、IQCH、IQCH-AS1、C15orf61、MAP2K5、SKOR1、RNU6-1、PIAS1、CALML4、CLN6、FEM1B、ITGA11、CORO2B、ANP32A、MIR4312、ANP32A-IT1、SPESP1、NOX5、LINC00277、GLCE、PAQR5、LOC145694、KIF23、RPLP1、LOC145837、LINC00593、TLE3、MIR629、UACA、LARP6、THAP10、LRRC49、CT62、THSD4、NR2E3、MYO9A、SENP8、GRAMD2、PKM、PARP6、CELF6、HEXA、HEXA-AS1、TMEM202、ARIH1、MIR630、LOC646670、GOLGA6B、HIGD2B、BBS4、ADPGK、ADPGK-AS1、NEO1、HCN4、C15orf60、NPTN、CD276、C15orf59、TBC1D21、LOXL1-AS1、LOXL1、STOML1、PML、GOLGA6A、LOC732265、LOC283731、ISLR2、ISLR、
STRA6、CCDC33、CYP11A1、LOC729739、SEMA7A、UBL7、LOC440288、ARID3B、CLK3、EDC3、CYP1A1、CYP1A2、CSK、MIR4513、LMAN1L、CPLX3、ULK3、SCAMP2、MPI、FAM219B、COX5A、RPP25、SCAMP5、PPCDC、C15orf39、GOLGA6C、GOLGA6D、COMMD4、NEIL1、MIR631、MAN2C1、SIN3A、PTPN9、SNUPN、IMP3、SNX33、CSPG4、ODF3L1、DNM1P35、MIR4313、LOC441728、LOC730058、UBE2Q2、FBXO22、FBXO22-AS1、NRG4、C15orf27、ETFA、TYRO3P、ISL2、SCAPER、MIR3713、RCN2、PSTPIP1、TSPAN3、PEAK1、LINC00597、HMG20A、LINGO1、LOC253044、LOC645752、LOC440292、LOC91450、TBC1D2B、SH2D7、CIB2、IDH3A、ACSBG1、DNAJA4、WDR61、CRABP1、IREB2、AGPHD1、PSMA4、CHRNA5、CHRNA3、CHRNB4、LOC646938、ADAMTS7、MORF4L1、CTSH、RASGRF1、LOC100129540、LOC729911、MIR184、ANKRD34C、TMED3、KIAA1024、MTHFS、ST20-MTHFS、ST20、C15orf37、BCL2A1、ZFAND6、FAH、LOC100996492、LOC283688、ARNT2、LOC100133746、FAM108C1、KIAA1199、MIR549、MESDC2、MIR4514、MESDC1、C15orf26、IL16、STARD5、TMC3、MEX3B、EFTUD1、FAM154B、LOC390660、GOLGA6L10、UBE2Q2P2、GOLGA6L9、LOC440297、AGSK1、RPS17、LOC643696、UBE2Q2P3、LOC727849、RPS17L、CPEB1、LOC283692、AP3B2、LOC338963、LOC283693、LOC100505616、SCARNA15、FSD2、WHAMM、HOMER2、FAM103A1、C15orf40、BTBD1、MIR4515、TM6SF1、HDGFRP3、BNC1、SH3GL3、ADAMTSL3、LOC648809、DNM1P41、LOC100505679、LOC440300、LOC388152、GOLGA6L4、GOLGA6L5、UBE2Q2P1、LOC100506874、ZSCAN2、SCAND2、WDR73、NMB、SEC11A、ZNF592、ALPK3、SLC28A1、PDE8A、LOC642423、GOLGA6L3、AKAP13、KLHL25、MIR1276、MIR548AP、AGBL1、LOC727915、LINC00052、NTRK3、NTRK3-AS1、MRPL46、MRPS11、DET1、MIR1179、MIR7-2、MIR3529、AEN、ISG20、ACAN、HAPLN3、MFGE8、ABHD2、RLBP1、FANCI、POLG、MIR9-3、LOC254559、RHCG、LOC283761、TICRR、KIF7、PLIN1、PEX11A、WDR93、MESP1、MESP2、ANPEP、AP3S2、C15orf38-AP3S2、MIR5094、MIR5009、C15orf38、ZNF710、MIR3174、IDH2、SEMA4B、CIB1、GDPGP1、TTLL13、NGRN、GABARAPL3、ZNF774、IQGAP1、CRTC3、LOC100507079、BLM、FURIN、FES、MAN2A2、UNC45A、HDDC3、RCCD1、PRC1、LOC100507118、VPS33B、SV2B、SLCO3A1、ST8SIA2、LOC100507166、C15orf32、LOC100144604、FAM174B、LOC643797、ASB9P1、LOC100507217、LOC100996653、CHD2、MIR3175、RGMA、UNQ9370、LOC100996663、MCTP2、LOC400456、LOC145820、LOC100507311、LOC100507288、NR2F2-AS1、NR2F2、MIR1469、LOC100507325、LOC100652749、SPATA8、LOC91948、ARRDC4、FAM169B、IGF1R、MIR4714、PGPEP1L、SYNM、TTC23、LRRC28、MEF2A、LYSMD4、DNM1P46、ADAMTS17、FLJ42289、CERS3、LINS、ASB7、LOC440313、ALDH1A3、LRRK1、CHSY1、VIMP、SNRPA1、PCSK6、LOC100507472、TM2D3、TARSL2、LOC100128108、OR4F6、
OR4F15、OR4F13P、OR4F4、FAM138E、MIR1302-10、WASH3P、DDX11L9、DDX11L10、POLR3K、SNRNP25、RHBDF1、MPG、NPRL3、HBZ、HBM、HBA2、HBA1、HBQ1、LUC7L、ITFG3、RGS11、ARHGDIG、PDIA2、AXIN1、MRPL28、TMEM8A、LOC100134368、NME4、DECR2、RAB11FIP3、LINC00235、SOLH、MIR5587、MIR3176、C16orf11、NHLRC4、PIGQ、RAB40C、WFIKKN1、C16orf13、LOC100287175、FAM195A、WDR90、RHOT2、RHBDL1、STUB1、JMJD8、WDR24、FBXL16、GS52、METRN、FAM173A、CCDC78、HAGHL、NARFL、MSLN、MIR662、RPUSD1、CHTF18、GNG13、PRR25、LMF1、SOX8、SSTR5-AS1、SSTR5、C1QTNF8、CACNA1H、TPSG1、TPSB2、TPSAB1、TPSD1、UBE2I、BAIAP3、TSR3、GNPTG、UNKL、C16orf91、CCDC154、CLCN7、PTX4、TELO2、IFT140、TMEM204、CRAMP1L、HN1L、MAPK8IP3、MIR3177、NME3、MRPS34、EME2、SPSB3、NUBP2、IGFALS、HAGH、FAHD1、MEIOB、LINC00254、HS3ST6、MSRB1、RPL3L、NDUFB10、RPS2、SNORA10、SNORA64、SNHG9、SNORA78、RNF151、TBL3、NOXO1、GFER、SYNGR3、ZNF598、NPW、SLC9A3R2、NTHL1、TSC2、PKD1、MIR1225、MIR4516、MIR3180-5、RAB26、LOC100507303、SNORD60、TRAF7、CASKIN1、MLST8、BRICD5、PGP、E4F1、DNASE1L2、ECI1、RNPS1、MIR3677、MIR940、MIR4717、ABCA3、ABCA17P、CCNF、C16orf59、NTN3、TBC1D24、ATP6V0C、AMDHD2、CEMP1、MIR3178、PDPK1、LOC652276、FLJ42627、ERVK13-1、KCTD5、PRSS27、SRRM2-AS1、SRRM2、TCEB2、PRSS33、PRSS41、PRSS21、ZG16B、PRSS30P、PRSS22、FLYWCH2、FLYWCH1、KREMEN2、PAQR4、PKMYT1、LINC00514、LOC100507378、CLDN9、CLDN6、TNFRSF12A、HCFC1R1、THOC6、CCDC64B、LOC100128770、MMP25、LOC100996528、LOC100507419、IL32、ZSCAN10、ZNF205-AS1、ZNF205、LOC100507458、ZNF213、CASP16、OR1F1、OR1F2P、ZNF200、MEFV、FLJ39639、ZNF263、TIGD7、ZNF75A、OR2C1、MTRNR2L4、ZNF434、ZNF174、ZNF597、NAA60、C16orf90、CLUAP1、NLRC3、SLX4、DNASE1、TRAP1、CREBBP、ADCY9、SRL、LOC100507501、TFAP4、GLIS2、PAM16、CORO7-PAM16、CORO7、VASN、DNAJA3、NMRAL1、HMOX2、CDIP1、C16orf96、FAM100A、MGRN1、NUDT16L1、ANKS3、C16orf71、ZNF500、SEPT12、LOC440335、ROGDI、GLYR1、UBN1、PPL、SEC14L5、NAGPA、NAGPA-AS1、C16orf89、ALG1、FAM86A、LOC100287538、RBFOX1、LOC440337、TMEM114、METTL22、ABAT、TMEM186、PMM2、CARHSP1、USP7、C16orf72、GRIN2A、ATF7IP2、LOC100287628、EMP2、TEKT5、NUBP1、FAM18A、CIITA、DEXI、LOC100505564、CLEC16A、SOCS1、TNP2、PRM3、PRM2、PRM1、MIR548H2、RMI2、LOC388210、LOC400499、LITAF、SNN、TXNDC11、ZC3H7A、BCAR4、RSL1D1、GSPT1、TNFRSF17、SNX29、FLJ32790、CPPED1、MIR4718、SHISA9、ERCC4、MKL2、LOC100129781、MIR193B、MIR365A、PARN、BFAR、PLA2G10、LOC642778、LOC100652777、LOC642799、ABCC6P2、NOMO1、MIR3179-1、
MIR3670-1、MIR3180-1、NPIP、PDXDC1、MIR1972-1、NTAN1、RRN3、MIR3180-4、LOC100288332、MPV17L、C16orf45、KIAA0430、NDE1、MIR484、MYH11、FOPNL、ABCC1、ABCC6、NOMO3、MIR3179-2、MIR3670-2、MIR3180-2、PKD1P1、XYLT1、LOC100996242、MIR3180-3、MIR3179-3、NOMO2、ABCC6P1、RPS15A、ARL6IP1、SMG1、TMC7、COQ7、ITPRIPL2、SYT17、CLEC19A、TMC5、GDE1、CCP110、C16orf62、C16orf88、IQCK、GPRC5B、GPR139、GP2、UMOD、PDILT、ACSM5、ACSM2A、ACSM2B、ACSM1、THUMPD1、ACSM3、ERI2、LOC81691、DCUN1D3、LYRM1、DNAH3、TMEM159、ZP2、ANKS4B、CRYM、CRYM-AS1、SNX29P1、NPIPL3、LOC100190986、LOC100271836、MIR3680-1、SLC7A5P2、METTL9、IGSF6、OTOA、RRN3P1、LOC100996277、UQCRC2、PDZD9、C16orf52、VWA3A、EEF2K、POLR3E、CDR2、RRN3P3、SMG1P1、LOC100132247、LOC653786、HS3ST2、USP31、SCNN1G、SCNN1B、COG7、GGA2、EARS2、UBFD1、NDUFAB1、PALB2、DCTN5、PLK1、ERN2、CHP2、PRKCB、CACNG3、RBBP6、FLJ45256、TNRC6A、SLC5A11、ARHGAP17、LOC554206、LOC283887、LCMT1、LOC100506655、AQP8、ZKSCAN2、HS3ST4、MIR548W、C16orf82、KDM8、NSMCE1、FLJ21408、IL4R、IL21R、IL21R-AS1、GTF3C1、KIAA0556、GSG1L、XPO6、LOC100506705、SBK1、LOC728741、EIF3CL、CLN3、APOBR、IL27、NUPR1、CCDC101、SULT1A2、SULT1A1、LOC728734、EIF3C、LOC100507607、ATXN2L、TUFM、MIR4721、SH2B1、ATP2A1、LOC100289092、RABEP2、CD19、NFATC2IP、MIR4517、SPNS1、LAT、RRN3P2、SNX29P2、LOC728888、LOC606724、BOLA2、SLX1B、SLX1B-SULT1A4、SULT1A4、LOC388242、LOC440354、MIR3680-2、SLC7A5P1、SPN、QPRT、C16orf54、ZG16、KIF22、MAZ、LOC100289283、PRRT2、PAGR1、MVP、CDIPT、LOC440356、SEZ6L2、ASPHD1、KCTD13、TMEM219、TAOK2、HIRIP3、INO80E、DOC2A、C16orf92、FAM57B、LOC100996332、ALDOA、PPP4C、TBX6、YPEL3、GDPD3、MAPK3、CORO1A、BOLA2B、SLX1A、SLX1A-SULT1A3、SULT1A3、LOC613038、LOC613037、LOC595101、CD2BP2、TBC1D10B、MYLPF、SEPT1、ZNF48、ZNF771、DCTPP1、SEPHS2、ITGAL、LOC100506928、MIR4518、ZNF768、ZNF747、LOC100996344、ZNF764、ZNF688、ZNF785、ZNF689、PRR14、FBRS、LOC730183、SRCAP、SNORA30、LOC100862671、PHKG2、C16orf93、RNF40、ZNF629、MIR4519、BCL7C、MIR762、CTF1、FBXL19-AS1、FBXL19、ORAI3、SETD1A、HSD3B7、STX1B、STX4、ZNF668、ZNF646、PRSS53、VKORC1、BCKDK、KAT8、LOC100507092、LOC100996366、PRSS8、PRSS36、FUS、PYCARD、LOC100652740、TRIM72、PYDC1、ITGAM、ITGAX、ITGAD、COX6A2、ZNF843、ARMC5、TGFB1I1、SLC5A2、C16orf58、LOC100128371、AHSP、CSDAP1、KIAA0664L3、ZNF720、ZNF267、LOC729264、LOC100507221、LOC390705、TP53TG3、SLC6A10P、TP53TG3C、TP53TG3B、LOC653562、LINC00273、LOC100505948、UBE2MP1、LOC283914、LOC146481、
LOC100130700、RNA5SP411、FLJ26245、ANKRD26P1、SHCBP1、VPS35、ORC6、MYLK3、C16orf87、GPT2、DNAJA2、NETO2、ITFG1、PHKB、LOC100507534、ABCC12、ABCC11、LONP2、LOC100507577、SIAH1、N4BP1、CBLN1、C16orf78、ZNF423、CNEP1R1、HEATR3、PAPD5、ADCY7、BRD7、NKD1、LOC100996329、SNX20、NOD2、CYLD、SALL1、LOC388276、LOC100505619、TOX3、LOC643714、CHD9、LOC643802、RBL2、AKTIP、RPGRIP1L、FTO、FTO-IT1、LOC100996338、IRX3、LOC100996345、CRNDE、IRX5、LOC100132339、IRX6、MMP2、LPCAT2、CAPNS2、SLC6A2、CES1P2、CES1P1、CES1、CES5A、LOC283856、GNAO1、DKFZP434H168、MIR3935、LOC100505722、AMFR、NUDT21、OGFOD1、BBS2、MT4、MT3、MT2A、MT1L、MT1E、MT1M、MT1JP、MT1A、MT1DP、MT1B、MT1F、MT1G、MT1H、MT1IP、MT1X、LOC100996353、NUP93、MIR138-2、SLC12A3、HERPUD1、CETP、NLRC5、CPNE2、FAM192A、RSPRY1、ARL2BP、PLLP、CCL22、CX3CL1、CCL17、CIAPIN1、COQ9、POLR2C、DOK4、CCDC102A、GPR114、GPR56、GPR97、CCDC135、KATNB1、KIFC3、LOC388282、CNGB1、TEPP、ZNF319、USB1、MMP15、C16orf80、CSNK2A2、CCDC113、PRSS54、GINS3、NDRG4、SETD6、CNOT1、SNORA46、SNORA50、SLC38A7、GOT2、LOC644649、LOC729159、CDH8、RNU6-21、CDH11、LOC283867、CDH5、LOC100505865、BEAN1、TK2、CKLF、CKLF-CMTM1、CMTM1、CMTM2、CMTM3、CMTM4、DYNC1LI2、CCDC79、NAE1、CA7、PDP2、CDH16、RRAD、FAM96B、CES2、CES3、CES4A、CBFB、C16orf70、B3GNT9、TRADD、FBXL8、HSF4、NOL3、KIAA0895L、EXOC3L1、E2F4、ELMO3、MIR328、LRRC29、TMEM208、FHOD1、SLC9A5、PLEKHG4、KCTD19、LRRC36、TPPP3、ZDHHC1、HSD11B2、ATP6V0D1、AGRP、LOC100505942、FAM65A、CTCF、RLTPR、ACD、PARD6A、ENKD1、C16orf86、GFOD2、RANBP10、TSNAXIP1、CENPT、THAP11、NUTF2、EDC4、NRN1L、PSKH1、CTRL、PSMB10、LCAT、SLC12A4、DPEP3、DPEP2、DDX28、DUS2L、NFATC3、ESRP2、PLA2G15、SLC7A6、SLC7A6OS、PRMT7、SMPD3、ZFP90、CDH3、CDH1、TMCO7、HAS3、CHTF8、CIRH1A、SNTB2、VPS4A、COG8、PDF、NIP7、TMED6、TERF2、CYB5B、MIR1538、NFAT5、NQO1、NOB1、WWP2、MIR140、CLEC18A、PDXDC2P、MIR1972-2、PDPR、CLEC18C、LOC100506060、EXOSC6、AARS、DDX19B、LOC100506083、DDX19A、ST3GAL2、RNU6-23、FUK、COG4、SF3B3、SNORD111B、SNORD111、IL34、MTSS1L、VAC14、LOC100130894、HYDIN、FTSJD1、CALB2、ZNF23、LOC100506105、ZNF19、CHST4、LOC100132529、TAT、MARVELD3、PHLPP2、SNORA70D、LOC100996499、AP1G1、SNORD71、ATXN1L、ZNF821、IST1、PKD1L3、DHODH、HP、HPR、TXNL4B、DHX38、PMFBP1、ZFHX3、HTA、C16orf47、LOC100506172、PSMD7、LOC283922、CLEC18B、GLG1、RFWD3、MLKL、FA2H、WDR59、ZNRF1、LDHD、ZFP1、CTRB2、CTRB1、BCAR1、CFDP1、TMEM170A、CHST6、CHST5、TMEM231、GABARAPL2、ADAT1、KARS、TERF2IP、CNTNAP4、
MIR4719、MON1B、SYCE1L、ADAMTS18、NUDT7、VAT1L、CLEC3A、WWOX、MAF、DYNLRB2、CDYL2、LOC100996425、CMC2、CENPN、ATMIN、C16orf46、GCSH、PKD1L2、BCMO1、GAN、MIR4720、CMIP、LOC100129617、PLCG2、SDR42E1、HSD17B2、MPHOSPH6、CDH13、MIR3182、HSBP1、MLYCD、OSGIN1、NECAB2、SLC38A8、MBTPS1、HSDL1、DNAAF1、TAF1C、ADAD2、LOC654780、KCNG4、WFDC1、ATP2C2、KIAA1609、COTL1、KLHL36、USP10、CRISPLD2、ZDHHC7、KIAA0513、FAM92B、LOC400548、LINC00311、MIR5093、GSE1、GINS2、C16orf74、MIR1910、EMC8、COX4I1、IRF8、LOC100506542、LOC146513、LOC732275、FOXF1-AS1、FOXF1、MTHFSD、FLJ30679、FOXC2、FOXL1、C16orf95、FBXO31、MAP1LC3B、ZCCHC14、JPH3、LOC100129215、KLHDC4、SLC7A5、CA5A、BANP、LOC400553、LOC100506735、ZNF469、ZFPM1、MIR5189、ZC3H18、IL17C、CYBA、MVD、SNAI3-AS1、SNAI3、RNF166、CTU2、PIEZO1、MIR4722、LOC100289580、FLJ40448、CDT1、APRT、GALNS、TRAPPC2L、PABPN1L、CBFA2T3、LOC642452、LOC100129697、LOC100506183、ACSF3、LINC00304、LOC400558、CDH15、SLC22A31、ZNF778、LOC642533、ANKRD11、LOC100287036、SPG7、RPL13、SNORD68、CPNE7、DPEP1、CHMP1A、C16orf55、CDK10、SPATA2L、VPS9D1、LOC100128881、ZNF276、FANCA、SPIRE2、TCF25、MC1R、TUBB3、DEF8、CENPBD1、AFG3L1P、DBNDD1、GAS8、C16orf3、LOC100130015、PRDM7、LOC100996541、LOC100506347、DOC2B、LOC100506371、RPH3AL、LOC100506388、C17orf97、FAM101B、VPS53、FAM57A、GEMIN4、DBIL5P、GLOD4、RNMTL1、NXN、TIMM22、ABR、MIR3183、BHLHA9、TUSC5、YWHAE、CRK、MYO1C、INPP5K、PITPNA-AS1、PITPNA、SLC43A2、SCARF1、RILP、PRPF8、TLCD2、MIR22HG、MIR22、WDR81、SERPINF2、SERPINF1、SMYD4、RPA1、RTN4RL1、DPH1、OVCA2、MIR132、MIR212、HIC1、SMG6、SRR、TSR1、SNORD91B、SNORD91A、SGSM2、MNT、LOC284009、METTL16、PAFAH1B1、KIAA0664、MIR1253、RAP1GAP2、OR1D5、OR1D2、OR1G1、LOC100288728、OR1A2、OR1A1、OR1D4、OR3A2、OR3A1、OR3A4P、OR1E1、OR3A3、OR1E2、SPATA22、ASPA、TRPV3、TRPV1、SHPK、CTNS、TAX1BP3、P2RX5-TAX1BP3、EMC6、P2RX5、ITGAE、GSG2、C17orf85、CAMKK1、P2RX1、ATP2A3、ZZEF1、CYB5D2、ANKFY1、UBE2G1、SPNS3、SPNS2、MYBBP1A、GGT6、SMTNL2、ALOX15、PELP1、ARRB2、MED11、CXCL16、ZMYND15、TM4SF5、VMO1、GLTPD2、PSMB6、PLD2、MINK1、CHRNE、C17orf107、GP1BA、SLC25A11、RNF167、PFN1、ENO3、SPAG7、CAMTA2、INCA1、KIF1C、SLC52A1、ZFP3、ZNF232、USP6、ZNF594、LOC100130950、SCIMP、RABEP1、NUP88、RPAIN、C1QBP、DHX33、DERL2、MIS12、LOC728392、NLRP1、LOC339166、WSCD1、AIPL1、FAM64A、PITPNM3、KIAA0753、TXNDC17、MED31、C17orf100、MIR4520A、MIR4520B、ALOX15P1、SLC13A5、XAF1、FBXO39、TEKT1、ALOX12P2、LOC100506713、ALOX12、RNASEK、RNASEK-C17orf49、C17orf49、MIR497HG、MIR195、MIR497、BCL6B、SLC16A13、SLC16A11、CLEC10A、ASGR2、ASGR1、DLG4、ACADVL、MIR324、DVL2、PHF23、GABARAP、CTDNEP1、ELP5、CLDN7、SLC2A4、YBX2、EIF5A、GPS2、NEURL4、ACAP1、KCTD11、TMEM95、TNK1、PLSCR3、C17orf61-PLSCR3、C17orf61、NLGN2、SPEM1、C17orf74、LOC100996282、TMEM102、FGF11、CHRNB1、ZBTB4、SLC35G6、POLR2A、TNFSF12、TNFSF12-TNFSF13、TNFSF13、SENP3、SENP3-EIF4A1、EIF4A1、SNORA48、SNORD10、SNORA67、CD68、MPDU1、SOX15、FXR2、SHBG、SAT2、ATP1B2、TP53、WRAP53、EFNB3、DNAH2、RPL29P2、KDM6B、TMEM88、LSMD1、CYB5D1、CHD3、SCARNA21、LOC284023、KCNAB3、TRAPPC1、CNTROB、GUCY2D、ALOX15B、ALOX12B、MIR4314、ALOXE3、HES7、PER1、VAMP2、TMEM107、SNORD118、MIR4521、MIR3676、C17orf59、AURKB、LINC00324、CTC1、PFAS、SLC25A35、RANGRF、ARHGEF15、ODF4、LOC100128288、KRBA2、RPL26、RNF222、NDEL1、MYH10、CCDC42、SPDYE4、MFSD6L、PIK3R6、PIK3R5、NTN1、STX8、WDR16、USP43、DHRS7C、GLP2R、RCVRN、GAS7、MYH13、MYH8、MYH4、MYH1、MYH2、MYH3、SCO1、ADPRM、TMEM220、MAGOH2、LINC00675、PIRT、SHISA6、DNAH9、ZNF18、MAP2K4、MIR744、LINC00670、MYOCD、ARHGAP44、MIR1269B、ELAC2、HS3ST3A1、MIR548H3、CDRT15P1、COX10-AS1、COX10、CDRT15、HS3ST3B1、MGC12916、FLJ45831、CDRT7、PMP22、MIR4731、TEKT3、FAM18B2-CDRT4、CDRT4、FAM18B2、CDRT1、TRIM16、ZNF286A、TBC1D26、CDRT15P2、MEIS3P1、ADORA2B、ZSWIM7、TTC19、NCOR1、PIGL、MIR1288、CENPV、UBB、TRPV2、C17orf76-AS1、SNORD49B、SNORD49A、SNORD65、FAM211A、ZNF287、ZNF624、CCDC144A、USP32P1、FAM106CP、KRT16P2、TBC1D27、TNFRSF13B、MPRIP、PLD6、FLCN、COPS3、NT5M、SMCR9、MED9、RASD1、PEMT、RAI1、SMCR5、SREBF1、MIR33B、TOM1L2、LOC100507131、LRRC48、ATPAF2、GID4、DRG2、MYO15A、ALKBH5、LLGL1、FLII、SMCR7、TOP3A、SMCR8、SHMT1、EVPLL、LOC339240、LGALS9C、USP32P2、FAM106A、CCDC144B、TBC1D28、ZNF286B、FOXO3B、TRIM16L、FBXW10、FAM18B1、PRPSAP2、SLC5A10、FAM83G、GRAP、SNORD3B-1、SNORD3B-2、SNORD3D、GRAPL、LOC79999、SNORD3A、SNORD3C、LOC388436、EPN2、EPN2-IT1、EPN2-AS1、B9D1、MIR1180、MAPK7、MFAP4、RNF112、SLC47A1、SNORA59B、ALDH3A2、SLC47A2、ALDH3A1、ULK2、AKAP10、SPECC1、LOC100131943、CCDC144C、LOC100996259、LGALS9B、KRT16P3、CDRT15L2、CCDC144NL、LOC339260、USP22、DHRS7B、TMEM11、C17orf103、MAP2K3、KCNJ12、C17orf51、FAM27L、FLJ36000、MTRNR2L1、LOC100506418、MIR4522、WSB1、TBC1D3P5、KSR1、LGALS9、NOS2、LYRM9、NLK、PYY2、PPY2、KRT18P55、TMEM97、IFT20、TNFAIP1、POLDIP2、TMEM199、MIR4723、SEBOX、VTN、SARM1、SLC46A1、SLC13A2、FOXN1、UNC119、PIGS、ALDOC、SPAG5、SPAG5-AS1、SGK494、KIAA0100、
SDF2、SUPT6H、PROCA1、RAB34、NARR、RPL23A、SNORD42B、SNORD4A、SNORD42A、SNORD4B、TLCD1、NEK8、TRAF4、FAM222B、ERAL1、MIR451A、MIR451B、MIR144、MIR4732、FLOT2、DHRS13、PHF12、SEZ6、PIPOX、MYO18A、TIAF1、CRYBA1、NUFIP2、MIR4523、TAOK1、ABHD15、TP53I13、GIT1、ANKRD13B、CORO6、SSH2、EFCAB5、NSRP1、MIR423、MIR3184、SLC6A4、BLMH、TMIGD1、CPD、GOSR1、TBC1D29、LRRC37BP1、SH3GL1P2、SUZ12P1、CRLF3、ATAD5、TEFM、ADAP2、RNF135、DPRXP4、LOC646021、MIR4733、NF1、OMG、EVI2B、EVI2A、RAB11FIP4、MIR4724、MIR193A、MIR4725、MIR365B、COPRS、UTP6、SUZ12、LRRC37B、SH3GL1P1、RHOT1、ARGFXP2、LOC100506596、RHBDL3、C17orf75、MIR632、ZNF207、PSMD11、CDK5R1、MYO1D、LOC100506629、LOC100506643、TMEM98、SPACA3、ASIC2、AA06、CCL2、CCL7、CCL11、CCL8、CCL13、CCL1、C17orf102、TMEM132E、CCT6B、ZNF830、LIG3、RAD51L3-RFFL、RFFL、RAD51D、FNDC8、NLE1、UNC45B、SLC35G3、SLFN5、SLFN11、SLFN12、SLFN13、SLFN12L、SLFN14、SNORD7、PEX12、AP2B1、RASL10B、GAS2L2、C17orf50、MMP28、TAF15、C17orf66、CCL5、RDM1、LYZL6、CCL16、CCL15-CCL14、CCL14、CCL15、CCL23、CCL18、CCL3、CCL4、TBC1D3B、CCL3L3、CCL4L1、TBC1D3C、CCL3L1、CCL4L2、TBC1D3H、TBC1D3G、ZNHIT3、MYO19、PIGW、GGNBP2、DHRS11、MRM1、LHX1、AATF、MIR2909、ACACA、C17orf78、TADA2A、DUSP14、SYNRG、DDX52、HNF1B、LOC284100、TBC1D3F、TBC1D3、LOC440434、MRPL45、GPR179、SOCS7、ARHGAP23、SRCIN1、C17orf96、MIR4734、MLLT6、MIR4726、CISD3、PCGF2、PSMB3、PIP4K2B、CWC25、MIR4727、C17orf98、RPL23、SNORA21、LASP1、LINC00672、FBXO47、LOC100996526、LRRC37A11P、LOC100131347、PLXDC1、ARL5C、CACNB1、RPL19、STAC2、FBXL20、MED1、CDK12、NEUROD2、PPP1R1B、STARD3、TCAP、PNMT、PGAP3、ERBB2、MIR4728、MIEN1、GRB7、IKZF3、ZPBP2、GSDMB、ORMDL3、LRRC3C、GSDMA、PSMD3、LOC100505620、CSF3、MED24、SNORD124、THRA、NR1D1、MSL1、CASC3、RAPGEFL1、WIPF2、CDC6、RARA、GJD3、TOP2A、IGFBP4、TNS4、CCR7、SMARCE1、KRT222、KRT24、KRT25、KRT26、KRT27、KRT28、KRT10、TMEM99、KRT12、KRT20、KRT23、KRT39、KRT40、KRTAP3-3、KRTAP3-2、KRTAP3-1、KRTAP1-5、KRTAP1-4、KRTAP1-3、KRTAP1-1、KRTAP2-1、KRTAP2-2、KRTAP2-3、KRTAP2-4、KRTAP4-7、KRTAP4-8、KRTAP4-9、KRTAP4-11、KRTAP4-12、KRTAP4-6、KRTAP4-5、KRTAP4-4、KRTAP4-3、KRTAP4-2、KRTAP4-1、KRTAP9-1、KRTAP9-2、KRTAP9-3、KRTAP9-8、KRTAP9-4、KRTAP9-9、KRTAP9-6、KRTAP9-7、KRTAP16-1、KRTAP17-1、KRT33A、KRT33B、KRT34、KRT31、LOC100505782、KRT37、KRT38、KRT32、KRT35、KRT36、KRT13、KRT15、KRT19、LOC147093、KRT9、KRT14、KRT16、KRT17、KRT42P、EIF1、GAST、HAP1、JUP、LEPREL4、FKBP10、NT5C3L、KLHL10、KLHL11、ACLY、
TTC25、CNP、DNAJC7、NKIRAS2、ZNF385C、LOC100507656、DHX58、KAT2A、HSPB9、RAB5C、KCNH4、HCRT、GHDC、STAT5B、STAT5A、STAT3、PTRF、ATP6V0A1、MIR548AT、MIR5010、NAGLU、HSD17B1、COASY、MLX、PSMC3IP、FAM134C、TUBG1、TUBG2、PLEKHH3、CCR10、CNTNAP1、EZH1、RAMP2-AS1、RAMP2、VPS25、WNK4、COA3、CNTD1、BECN1、PSME3、AOC2、AOC3、AOC4、LINC00671、G6PC、PTGES3L-AARSD1、AARSD1、PTGES3L、RUNDC1、RPL27、IFI35、VAT1、RND2、BRCA1、NBR2、NBR1、TMEM106A、TMEM106A-AS1、LOC100130581、ARL4D、MIR2117、DHX8、ETV4、MEOX1、SOST、DUSP3、C17orf105、MPP3、CD300LG、MPP2、FAM215A、LOC100996563、PPY、PYY、NAGS、TMEM101、LSM12、G6PC3、HDAC5、C17orf53、ASB16、ASB16-AS1、TMUB2、ATXN7L3、UBTF、SLC4A1、RUNDC3A、SLC25A39、GRN、FAM171A2、ITGA2B、GPATCH8、FZD2、C17orf104、CCDC43、DBF4B、ADAM11、GJC1、HIGD1B、EFTUD2、CCDC103、GFAP、KIF18B、C1QL1、DCAKD、NMT1、PLCD3、ACBD4、HEXIM1、HEXIM2、FMNL1、MAP3K14-AS1、SPATA32、MAP3K14、ARHGAP27、PLEKHM1、MIR4315-1、LRRC37A4P、LOC644172、CRHR1、MGC57346、CRHR1-IT1、MAPT-AS1、SPPL2C、MAPT、MAPT-IT1、STH、KANSL1、KANSL1-AS1、LRRC37A、ARL17B、NSFP1、LRRC37A2、ARL17A、NSF、WNT3、WNT9B、GOSR2、MIR5089、RPRML、CDC27、MYL4、ITGB3、EFCAB13、MRPL45P2、NPEPPS、KPNB1、TBKBP1、TBX21、OSBPL7、MRPL10、LRRC46、SCRN2、SP6、LOC100506295、SP2、LOC100506325、PNPO、PRR15L、CDK5RAP3、COPZ2、MIR152、NFE2L1、CBX1、SNX11、SKAP1、MIR1203、HOXB1、HOXB2、HOXB-AS1、HOXB3、HOXB4、MIR10A、HOXB-AS3、HOXB5、HOXB6、HOXB7、HOXB8、HOXB9、MIR196A1、LOC100506373、PRAC、HOXB-AS5、MIR3185、HOXB13、TTLL6、CALCOCO2、ATP5G1、UBE2Z、SNF8、GIP、IGF2BP1、B4GALNT2、GNGT2、ABI3、PHOSPHO1、FLJ40194、ZNF652、PHB、NGFR、LOC100288866、NXPH3、SPOP、SLC35B1、FAM117A、KAT7、TAC4、FLJ45513、DLX4、DLX3、LOC284080、ITGA3、PDK2、SAMD14、PPP1R9B、SGCA、HILS1、COL1A1、TMEM92、XYLT2、MRPL27、EME1、LRRC59、ACSF2、CHAD、RSAD1、MYCBPAP、EPN3、SPATA20、CACNA1G-AS1、CACNA1G、ABCC3、ANKRD40、LUC7L3、LINC00483、WFIKKN2、TOB1、TOB1-AS1、LOC100506609、SPAG9、NME1-NME2、NME1、NME2、MBTD1、UTP18、FLJ42842、CA10、C17orf112、KIF2B、TOM1L1、COX11、STXBP4、HLF、MMD、TMEM100、PCTP、ANKFN1、NOG、C17orf67、DGKE、MTVR2、TRIM25、MIR3614、COIL、SCPEP1、RNF126P1、AKAP1、MSI2、MRPS23、CUEDC1、VEZF1、FLJ44342、SRSF1、DYNLL2、OR4D1、MSX2P1、OR4D2、EPX、MKS1、LPO、MPO、BZRAP1、BZRAP1-AS1、MIR142、MIR4736、SUPT4H1、RNF43、HSF5、MTMR4、SEPT4、C17orf47、TEX14、RAD51C、PPM1E、TRIM37、SKA2、MIR454、MIR301A、PRR11、SMG8、GDPD1、YPEL2、MIR4729、DHX40、CLTC、CLTC-IT1、PTRH2、
VMP1、MIR21、TUBD1、RPS6KB1、RNFT1、TBC1D3P1-DHX40P1、MIR4737、HEATR6、LOC645638、LOC653653、LOC100996660、CA4、USP32、SCARNA20、LOC100506882、C17orf64、APPBP2、PPM1D、BCAS3、TBX2、C17orf82、TBX4、NACA2、BRIP1、INTS2、MED13、TBC1D3P2、EFCAB3、METTL2A、TLK2、MRC2、MARCH10、MIR633、TANC2、CYB561、ACE、KCNH6、DCAF7、TACO1、MAP3K3、LIMD2、LOC729683、STRADA、CCDC47、DDX42、FTSJ3、PSMC5、SMARCD2、TCAM1P、CSH2、GH2、CSH1、CSHL1、GH1、CD79B、SCN4A、C17orf72、ICAM2、ERN1、SNORD104、SNORA76、TEX2、PECAM1、MILR1、POLG2、DDX5、MIR3064、MIR5047、CEP95、SMURF2、LOC146880、PLEKHM1P、MIR4315-2、LRRC37A3、AMZ2P1、GNA13、LOC100507002、RGS9、AXIN2、CEP112、APOH、PRKCA、MIR634、CACNG5、CACNG4、CACNG1、HELZ、LOC100996368、PSMD12、PITPNC1、MIR548D2、MIR548AA2、NOL11、SNORA38B、BPTF、C17orf58、KPNA2、LINC00674、LOC440461、AMZ2、ARSG、SLC16A6、WIPI1、MIR635、PRKAR1A、FAM20A、ABCA8、ABCA9、ABCA6、MIR4524B、MIR4524A、ABCA10、ABCA5、MAP2K6、KCNJ16、KCNJ2-AS1、KCNJ2、FLJ37644、SOX9、LINC00673、LINC00511、SLC39A11、SSTR2、COG1、FAM104A、C17orf80、CPSF4L、CDC42EP4、SDK2、LOC100134391、LINC00469、LOC400620、RPL38、MGC16275、TTYH2、DNAI2、KIF19、BTBD17、GPR142、GPRC5C、CD300A、CD300LB、CD300C、CD300LD、C17orf77、CD300E、RAB37、CD300LF、SLC9A3R1、MIR3615、NAT9、TMEM104、GRIN2C、FDXR、FADS6、USH1G、OTOP2、OTOP3、HID1、CDR2L、ICT1、ATP5H、KCTD2、LOC100996374、SLC16A5、ARMC7、NT5C、HN1、SUMO2、NUP85、GGA3、MRPS7、MIF4GD、LOC100287042、SLC25A19、GRB2、MIR3678、KIAA0195、CASKIN2、TSEN54、LLGL2、MYO15B、RECQL5、SMIM5、SMIM6、SAP30BP、ITGB4、GALK1、H3F3B、MIR4738、UNK、LOC100507191、UNC13D、WBP2、TRIM47、TRIM65、MRPL38、FBF1、ACOX1、TEN1-CDK3、TEN1、CDK3、EVPL、SRP68、GALR2、ZACN、EXOC7、FOXJ1、RNF157-AS1、RNF157、FAM100B、QRICH2、PRPSAP1、SPHK1、UBE2O、AANAT、RHBDF2、CYGB、PRCD、SNHG16、SNORD1C、SNORD1B、SNORD1A、ST6GALNAC2、ST6GALNAC1、MXRA7、JMJD6、METTL23、SRSF2、MIR636、MFSD11、MGAT5B、SEC14L1、LINC00338、SCARNA16、SEPT9、MIR4316、LOC100507351、LOC100132174、FLJ45079、TNRC6C、LOC100131096、TMC6、TMC8、C17orf99、SYNGR2、TK1、AFMID、BIRC5、TMEM235、LOC100996291、SOCS3、PGS1、DNAH17、LOC100996295、CYTH1、USP36、TIMP2、LOC100653515、LGALS3BP、CANT1、LOC100507410、C1QTNF1、ENGASE、RBFOX3、MIR4739、HP09025、ENPP7、CBX2、CBX8、LOC100507425、CBX4、TBC1D16、CCDC40、MIR1268B、GAA、EIF4A3、CARD14、SGSH、SLC26A11、RNF213、LOC100294362、ENDOV、LOC100507440、MIR4730、NPTX1、RPTOR、LOC100128105、FLJ46026、CHMP6、PP13、BAIAP2-AS1、BAIAP2、
AATK、MIR657、MIR3065、MIR338、MIR1250、AATK-AS1、AZI1、ENTHD2、C17orf89、SLC38A10、LINC00482、TMEM105、LOC100130370、LOC100507520、BAHCC1、MIR4740、MIR3186、ACTG1、FSCN2、C17orf70、NPLOC4、TSPAN10、PDE6G、OXLD1、CCDC137、ARL16、HGS、MRPL12、SLC25A10、GCGR、FAM195B、PPP1R27、P4HB、ARHGDIA、ALYREF、ANAPC11、NPB、PCYT2、SIRT7、MAFG、MAFG-AS1、PYCR1、MYADML2、NOTUM、ASPSCR1、STRA13、LRRC45、RAC3、DCXR、RFNG、GPS1、DUS1L、FASN、CCDC57、SLC16A3、CSNK1D、CD7、SECTM1、TEX19、UTS2R、OGFOD3、HEXDC、HEXDC-IT1、C17orf62、NARF、FOXK2、WDR45L、RAB40B、MIR4525、FN3KRP、FN3K、TBCD、ZNF750、B3GNTL1、METRNL、LOC100505909、FLJ43681、ROCK1P1、USP14、THOC1、COLEC12、CETN1、CLUL1、C18orf56、TYMS、ENOSF1、YES1、ADCYAP1、LINC00470、LOC100652823、METTL4、NDC80、CBX3P2、SMCHD1、EMILIN2、LPIN2、LOC727896、MYOM1、MYL12A、MYL12B、TGIF1、LOC100505592、DLGAP1、DLGAP1-AS1、DLGAP1-AS2、DLGAP1-AS3、DLGAP1-AS5、C18orf42、LINC00526、LINC00667、ZFP161、EPB41L3、LOC645355、MIR3976、TMEM200C、L3MBTL4、MIR4317、LOC100130480、ARHGAP28、LINC00668、LAMA1、LRRC30、PTPRM、LOC100192426、RAB12、LOC100287082、SOGA2、NDUFV2、ANKRD12、TWSG1、RALBP1、PPP4R1、RAB31、TXNDC2、VAPA、APCDD1、NAPG、PIEZO2、SLC35G4、GNAL、CHMP1B、MPPE1、IMPA2、C18orf61、CIDEA、TUBB6、AFG3L2、SLMO1、SPIRE1、PSMG2、CEP76、LOC100996324、PTPN2、SEH1L、CEP192、LDLRAD4、LOC100288122、MIR5190、MIR4526、FAM210A、RNMT、MC5R、MC2R、ZNF519、ANKRD20A5P、CYP4F35P、CXADRP3、POTEC、ANKRD30B、MIR3156-2、LOC644669、ROCK1、GREB1L、ESCO1、SNRPD1、ABHD3、MIR320C1、MIB1、MIR133A1、MIR1-2、LOC100128893、GATA6、CTAGE1、RBBP8、MIR4741、CABLES1、TMEM241、RIOK3、C18orf8、NPC1、ANKRD29、LAMA3、TTC39C、CABYR、OSBPL1A、MIR320C2、LOC100996382、IMPACT、HRH4、LOC729950、ZNF521、SS18、PSMA8、TAF4B、LOC100506787、KCTD1、LOC728606、AQP4、AQP4-AS1、CHST9、CDH2、MIR302F、DSC3、DSC2、DSC1、DSG1、DSG4、DSG3、DSG2、LOC100652770、TTR、B4GALT6、LOC646778、SLC25A52、TRAPPC8、RNF125、RNF138、MEP1B、FAM59A、WBP11P1、KLHL14、CCDC178、ASXL3、NOL4、LOC100996400、DTNA、MAPRE2、ZNF397、ZSCAN30、ZNF271、ZNF24、ZNF396、INO80C、MIR3975、GALNT1、MIR187、MIR3929、C18orf21、RPRD1A、SLC39A6、ELP2、MOCOS、FHOD3、TPGS2、KIAA1328、LOC100506821、CELF4、LOC100506837、MIR4318、LINC00669、MIR924、MIR5583-2、MIR5583-1、KC6、PIK3C3、LOC284260、RIT2、SYT4、SETBP1、MIR4319、SLC14A2、LOC100652778、SLC14A1、SIGLEC15、EPG5、PSTPIP2、ATP5A1、HAUS1、C18orf25、RNF165、LOXHD1、ST8SIA5、PIAS2、KATNAL2、TCEB3CL2、TCEB3CL、TCEB3C、TCEB3B、
HDHD2、IER3IP1、SKOR2、MIR4527、SMAD2、ZBTB7C、LOC100127909、C18orf12、CTIF、MIR4743、SMAD7、DYM、MIR4744、RPL17-C18ORF32、C18orf32、MIR1539、RPL17、SNORD58C、SNORD58A、SNORD58B、LIPG、ACAA2、SCARNA17、MYO5B、MIR4320、CCDC11、MBD1、CXXC1、SKA1、MAPK4、MRO、ME2、ELAC1、SMAD4、MEX3C、LOC100287225、DCC、MBD2、SNORA37、POLI、STARD6、C18orf54、DYNAP、RAB27B、CCDC68、TCF4、MIR4529、LOC100132501、FLJ45743、LOC100505474、TXNL1、WDR7、LINC-ROR、BOD1L2、ST8SIA3、ONECUT2、FECH、NARS、LOC100505549、ATP8B1、NEDD4L、MIR122、MIR3591、ALPK2、MALT1、ZNF532、OACYLP、SEC11C、GRP、RAX、CPLX4、LMAN1、CCBE1、PMAIP1、MC4R、CDH20、LOC100130938、LOC100996669、RNF152、PIGN、KIAA1468、TNFRSF11A、ZCCHC2、PHLPP1、BCL2、KDSR、VPS4B、SERPINB5、SERPINB12、SERPINB13、SERPINB4、SERPINB3、SERPINB11、SERPINB7、SERPINB2、SERPINB10、HMSD、SERPINB8、LINC00305、LOC284294、LOC400654、CDH7、CDH19、MIR5011、DSEL、LOC643542、TMX3、CCDC102B、RNU6-39、DOK6、CD226、RTTN、SOCS6、LOC100505776、CBLN2、NETO1、MIR548AV、LOC100505797、LOC400655、LOC100505817、FBXO15、TIMM21、CYB5A、C18orf63、FAM69C、CNDP2、CNDP1、LOC400657、ZNF407、ZADH2、TSHZ1、C18orf62、LOC339298、ZNF516、FLJ44313、LOC284276、LINC00683、FLJ44881、LOC100131655、ZNF236、MBP、GALR1、LOC645321、SALL3、ATP9B、LOC100996274、NFATC1、FLJ25715、CTDP1、KCNG2、PQLC1、HSBP1L1、TXNL4A、RBFA、LOC100506070、ADNP2、PARD6G-AS1、PARD6G、LOC100506089、WASH5P、MIR1302-11、FAM138F、OR4F17、FLJ45445、LOC100996328、PPAP2C、MIER2、THEG、C2CD4C、SHC2、ODF3L2、MADCAM1、TPGS1、CDC34、GZMM、BSG、HCN2、POLRMT、FGF22、RNF126、FSTL3、PRSS57、PALM、C19orf21、PTBP1、MIR4745、LPPR3、MIR3187、AZU1、PRTN3、ELANE、CFD、MED16、R3HDM4、KISS1R、ARID3A、WDR18、GRIN3B、C19orf6、CNN2、ABCA7、HMHA1、POLR2E、GPX4、SBNO2、STK11、C19orf26、ATP5D、MIDN、CIRBP-AS1、CIRBP、C19orf24、EFNA2、MUM1、NDUFS7、GAMT、DAZAP1、RPS15、APC2、C19orf25、PCSK4、REEP6、ADAMTSL5、PLK5、MEX3D、MBD3、UQCR11、TCF3、ONECUT3、ATP8B3、REXO1、MIR1909、LOC100288123、KLF16、FAM108A1、ADAT3、SCAMP4、CSNK1G2、CSNK1G2-AS1、BTBD2、MKNK2、MOB3A、IZUMO4、AP3D1、DOT1L、PLEKHJ1、MIR1227、SF3A2、AMH、MIR4321、JSRP1、OAZ1、C19orf35、LINGO3、LOC100129831、LSM7、SPPL2B、TMPRSS9、TIMM13、LMNB2、GADD45B、GNG7、DIRAS1、SLC39A3、SGTA、THOP1、ZNF554、ZNF555、ZNF556、ZNF57、ZNF77、TLE6、TLE2、AES、GNA11、GNA15、S1PR4、NCLN、CELF5、NFIC、C19orf77、DOHH、FZR1、MFSD12、C19orf71、HMG20B、GIPC3、TBXA2R、CACTIN-AS1、CACTIN、PIP5K1C、TJP3、APBA3、MRPL54、
RAX2、MATK、ZFR2、ATCAY、NMRK2、DAPK3、MIR637、EEF2、SNORD37、PIAS4、ZBTB7A、MAP2K2、CREB3L3、SIRT6、ANKRD24、EBI3、CCDC94、SHD、TMIGD2、FSD1、STAP2、MPND、SH3GL1、CHAF1A、UBXN6、MIR4746、HDGFRP2、PLIN4、PLIN5、LRG1、SEMA6B、TNFAIP8L1、C19orf10、DPP9、LOC100131094、MIR7-3HG、MIR7-3、FEM1A、TICAM1、PLIN3、ARRDC5、UHRF1、MIR4747、KDM4B、PTPRS、ZNRF4、PLAC2、SAFB2、SAFB、C19orf70、HSD11B1L、RPL36、LONP1、CATSPERD、PRR22、DUS3L、NRTN、FUT6、FUT3、FUT5、NDUFA11、VMAC、CAPS、RANBP3、LOC100128568、RFX2、ACSBG2、MLLT1、ACER1、CLPP、ALKBH7、PSPN、GTF2F1、KHSRP、MIR3940、SLC25A41、SLC25A23、CRB3、DENND1C、TUBB4A、TNFSF9、CD70、TNFSF14、C3、GPR108、TRIP10、SH2D3A、VAV1、EMR1、EMR4P、FLJ25758、LOC729458、MBD3L5、MBD3L4、MBD3L2、MBD3L3、ZNF557、INSR、LOC100996405、LOC100996504、ARHGEF18、LOC100128573、PEX11G、C19orf45、ZNF358、MCOLN1、PNPLA6、CAMSAP3、XAB2、PET100、PCP2、STXBP2、RETN、C19orf59、TRAPPC5、FCER2、CLEC4G、CD209、CLEC4M、CLEC4GP1、EVI5L、FLJ22184、LOC388499、LRRC8E、MAP2K7、TGFBR3L、SNAPC2、CTXN1、TIMM44、ELAVL1、CCL25、FBN3、CERS4、CD320、NDUFA7、RPS28、KANK3、ANGPTL4、RAB11B-AS1、MIR4999、RAB11B、MARCH2、HNRNPM、PRAM1、ZNF414、MYO1F、ADAMTS10、ACTL9、OR2Z1、ZNF558、MBD3L1、MUC16、OR1M1、OR7G2、OR7G1、OR7G3、ZNF317、OR7D2、OR7D4、OR7E24、ZNF699、ZNF559、ZNF559-ZNF177、ZNF177、ZNF266、ZNF560、ZNF426、ZNF121、ZNF561、LOC284385、ZNF562、ZNF812、ZNF846、LOC100505555、FBXL12、UBL5、LOC100996288、PIN1、OLFM2、COL5A3、RDH8、MIR5589、C3P1、C19orf66、ANGPTL6、PPAN-P2RY11、PPAN、SNORD105、SNORD105B、P2RY11、EIF3G、DNMT1、S1PR2、MIR4322、MRPL4、ICAM1、ICAM4、ICAM5、ZGLP1、FDX1L、RAVER1、ICAM3、TYK2、CDC37、MIR1181、PDE4A、KEAP1、S1PR5、ATG4D、MIR1238、KRI1、CDKN2D、AP1M2、SLC44A2、ILF3-AS1、ILF3、QTRT1、DNM2、MIR638、MIR4748、MIR199A1、TMED1、C19orf38、CARM1、YIPF2、C19orf52、SMARCA4、LDLR、SPC24、KANK2、DOCK6、C19orf80、TSPAN16、RAB3D、TMEM205、CCDC159、LPPR2、SWSAP1、EPOR、RGL3、CCDC151、PRKCSH、ELAVL3、ZNF653、ECSIT、CNN1、ELOF1、ACP5、ZNF627、HNRNPA1P10、ZNF833P、ZNF823、ZNF441、ZNF491、ZNF440、ZNF439、ZNF69、ZNF700、ZNF763、ZNF433、ZNF878、ZNF844、ZNF788、LOC100996289、ZNF20、ZNF625-ZNF20、ZNF625、ZNF136、ZNF44、ZNF563、ZNF442、ZNF799、ZNF443、ZNF709、ZNF564、ZNF490、ZNF791、MAN2B1、WDR83、WDR83OS、DHPS、FBXW9、TNPO2、SNORD41、C19orf43、ASNA1、BEST2、HOOK2、MIR5684、JUNB、PRDX2、RNASEH2A、RTBDN、MAST1、DNASE2、KLF1、GCDH、SYCE2、MIR5695、FARSA、CALR、RAD23A、GADD45GIP1、DAND5、NFIX、LYL1、TRMT1、
NACC1、STX10、IER2、CACNA1A、LOC100507353、CCDC130、MRI1、C19orf53、ZSWIM4、LOC284454、MIR24-2、MIR27A、MIR23A、LOC100996314、MIR181C、MIR181D、NANOS3、C19orf57、CC2D1A、PODNL1、DCAF15、RFX1、RLN3、IL27RA、PALM3、LOC113230、C19orf67、SAMD1、PRKACA、ASF1B、LOC100507373、LPHN1、CD97、DDX39A、PKN1、PTGER1、GIPC1、DNAJB1、MIR639、TECR、NDUFB7、CLEC17A、EMR3、ZNF333、EMR2、OR7C1、OR7A5、OR7A10、OR7A17、OR7C2、SLC1A6、CCDC105、CASP14、OR1I1、SYDE1、ILVBL、NOTCH3、EPHX3、BRD4、AKAP8、AKAP8L、WIZ、MIR1470、RASAL3、PGLYRP2、CYP4F22、CYP4F8、CYP4F3、CYP4F12、OR10H2、OR10H3、CYP4F24P、OR10H5、OR10H1、UCA1、CYP4F2、CYP4F11、OR10H4、LINC00661、FLJ25328、TPM4、RAB8A、HSH2D、CIB3、FAM32A、AP1M1、KLF2、EPS15L1、CALR3、C19orf44、CHERP、SLC35E1、MED26、SMIM7、TMEM38A、NWD1、SIN3B、F2RL3、CPAMD8、HAUS8、MYO9B、USE1、OCEL1、NR2F6、USHBP1、BABAM1、ANKLE1、ABHD8、MRPL34、DDA1、ANO8、GTPBP3、PLVAP、BST2、LOC100507535、FAM125A、TMEM221、NXNL1、SLC27A1、PGLS、FAM129C、GLT25D1、UNC13A、MAP1 S、FCHO1、B3GNT3、INSL3、JAK3、RPL18A、SNORA68、SLC5A5、CCDC124、KCNN1、ARRDC2、IL12RB1、MAST3、PIK3R2、IFI30、MPV17L2、RAB3A、PDE4C、LOC729966、KIAA1683、JUND、MIR3188、LSM4、PGPEP1、GDF15、MIR3189、LRRC25、SSBP4、ISYNA1、ELL、FKBP8、KXD1、UBA52、C19orf60、CRLF1、TMEM59L、KLHL26、CRTC1、COMP、UPF1、CERS1、GDF1、COPE、DDX49、HOMER3、SUGP2、ARMC6、SLC25A42、TMEM161A、MEF2BNB-MEF2B、MEF2B、MEF2BNB、RFXANK、NR2C2AP、NCAN、HAPLN4、TM6SF2、SUGP1、MAU2、GATAD2A、MIR640、TSSK6、NDUFA13、YJEFN3、CILP2、PBX4、LPAR2、GMIP、ATP13A1、ZNF101、ZNF14、LINC00663、ZNF506、ZNF253、ZNF93、ZNF682、ZNF90、ZNF486、MIR1270-1、ZNF826P、MIR1270-2、ZNF737、ZNF626、ZNF85、ZNF430、ZNF714、ZNF431、ZNF708、ZNF738、ZNF493、LOC400680、ZNF429、LOC100505594、ZNF100、LOC641367、ZNF43、ZNF208、ZNF257、ZNF676、ZNF729、ZNF98、LOC100128139、LOC440518、LOC100996349、LOC374890、ZNF492、ZNF99、ZNF728、ZNF724P、LOC100132815、ZNF91、ZNF675、ZNF681、RPSAP58、ZNF726、LOC100505851、LOC100996381、ZNF254、HAVCR1P1、LINC00662、LOC148145、LOC100505835、UQCRFS1、LOC284395、VSTM2B、POP4、PLEKHF1、C19orf12、CCNE1、URI1、ZNF536、DKFZp566F0947、TSHZ3、THEG5、LOC100996440、LOC100996665、ZNF507、LOC400684、DPY19L3、PDCD5、ANKRD27、RGS9BP、NUDT19、TDRD12、SLC7A9、CEP89、C19orf40、RHPN2、GPATCH1、WDR88、LRP3、SLC7A10、CEBPA、CEBPA-AS1、CEBPG、PEPD、LOC100996672、LOC100996681、CHST8、KCTD15、LSM14A、KIAA0355、FLJ21369、GPI、PDCD2L、UBA2、WTIP、ZNF807、SCGB1B2P、SCGB2B2、SCGB2B3P、
ZNF302、ZNF181、ZNF599、LOC400685、LOC100652909、LOC100652911、ZNF30、ZNF792、GRAMD1A、SCN1B、HPN、LOC100128675、FXYD3、LGI4、FXYD1、FXYD7、FXYD5、FAM187B、LSR、USF2、HAMP、MAG、CD22、MIR5196、FFAR1、FFAR3、LOC100128682、FFAR2、KRTDAP、DMKN、SBSN、GAPDHS、LOC100506469、TMEM147、ATP4A、HAUS5、RBM42、ETV2、COX6B1、UPK1A、UPK1A-AS1、ZBTB32、MLL4、IGFLR1、U2AF1L4、PSENEN、LIN37、HSPB6、C19orf55、ARHGAP33、PRODH2、NPHS1、KIRREL2、APLP1、NFKBID、HCST、TYROBP、LRFN3、SDHAF1、SYNE4、ALKBH6、CLIP3、THAP8、WDR62、OVOL3、POLR2I、TBCB、CAPNS1、COX7A1、ZNF565、ZNF146、LOC100134317、LINC00665、ZFP14、ZFP82、LOC644189、ZNF566、LOC728752、ZNF260、ZNF529、ZNF382、ZNF461、ZNF567、ZNF850、ZNF790-AS1、ZNF790、ZNF345、ZNF829、ZNF568、ZNF420、ZNF585A、ZNF585B、ZNF383、LOC284412、LOC100507342、HKR1、ZNF527、ZNF569、ZNF570、ZNF793、LOC400692、LOC100507433、ZNF540、ZNF571、ZFP30、ZNF781、ZNF607、LOC100507486、ZNF573、LOC644554、LOC100631378、WDR87、SIPA1L3、DPF1、PPP1R14A、SPINT2、YIF1B、C19orf33、KCNK6、CATSPERG、PSMD8、GGN、SPRED3、FAM98C、RASGRP4、RYR1、MAP4K1、EIF3K、ACTN4、CAPN12、LGALS7、LGALS7B、LGALS4、ECH1、HNRNPL、RINL、SIRT2、NFKBIB、LOC643669、SARS2、MRPS12、FBXO17、FBXO27、PAPL、PAK4、NCCRP1、SYCN、IL28B、IL28A、IL29、LRFN1、GMFG、SAMD4B、PAF1、MED29、ZFP36、MIR4530、PLEKHG2、RPS16、LOC723805、SUPT5H、TIMM50、DLL3、SELV、EID2B、EID2、LGALS13、LOC100129935、LGALS16、LGALS17A、LGALS14、CLC、LEUTX、DYRK1B、FBL、FCGBP、PSMC4、ZNF546、ZNF780B、ZNF780A、MAP3K10、TTC9B、CNTD2、AKT2、LOC100507646、MIR641、C19orf47、PLD3、HIPK4、PRX、SERTAD1、SERTAD3、BLVRB、SPTBN4、SHKBP1、LTBP4、NUMBL、ADCK4、ITPKC、C19orf54、SNRPA、MIA、MIA-RAB4B、RAB4B、RAB4B-EGLN2、EGLN2、CYP2A6、CYP2A7、CYP2G1P、CYP2B7P1、CYP2B6、CYP2A13、CYP2F1、CYP2S1、AXL、HNRNPUL1、CCDC97、TGFB1、B9D2、TMEM91、EXOSC5、BCKDHA、B3GNT8、ATP5SL、C19orf69、LOC100505495、CEACAM21、CEACAM4、CEACAM7、CEACAM5、CEACAM6、CEACAM3、LYPD4、DMRTC2、RPS19、CD79A、ARHGEF1、LOC100505585、RABAC1、ATP1A3、GRIK5、ZNF574、POU2F2、LOC100505622、MIR4323、DEDD2、ZNF526、GSK3A、LOC100132272、ERF、LOC100652741、CIC、PAFAH1B3、PRR19、TMEM145、MEGF8、CNFN、LOC100996307、LIPE、CXCL17、CEACAM1、CEACAM8、PSG3、PSG8、LOC100289650、PSG10P、PSG1、PSG6、PSG7、PSG11、PSG2、PSG5、PSG4、LOC284344、PSG9、PRG1、CD177、TEX101、LYPD3、PHLDB3、ETHE1、ZNF575、XRCC1、PINLYP、IRGQ、ZNF576、ZNF428、SRRM5、CADM4、PLAUR、IRGC、SMG9、KCNN4、LYPD5、ZNF283、ZNF404、LOC100505715、ZNF45、ZNF221、
ZNF155、ZNF230、ZNF222、ZNF223、ZNF284、ZNF224、LOC100379224、ZNF225、ZNF234、ZNF226、ZNF227、ZNF233、ZNF235、ZFP112、ZNF285、ZNF229、ZNF180、CEACAM20、CEACAM22P、IGSF23、PVR、MIR4531、CEACAM19、CEACAM16、BCL3、CBLC、BCAM、PVRL2、TOMM40、APOE、APOC1、APOC1P1、APOC4-APOC2、APOC4、APOC2、CLPTM1、RELB、CLASRP、ZNF296、GEMIN7、PPP1R37、NKPD1、TRAPPC6A、BLOC1S3、EXOC3L2、MARK4、CKM、KLC3、ERCC2、PPP1R13L、CD3EAP、ERCC1、FOSB、RTN2、PPM1N、VASP、OPA3、GPR4、EML2、MIR330、LOC100287177、GIPR、MIR642A、MIR642B、SNRPD2、QPCTL、FBXO46、LOC388553、SIX5、DMPK、DMWD、RSPH6A、SYMPK、FOXA3、IRF2BP1、MYPOP、NANOS2、NOVA2、CCDC61、MIR769、PGLYRP1、IGFL4、IGFL3、IGFL2、DKFZp434J0226、IGFL1、HIF3A、PPP5C、CCDC8、PNMAL1、PPP5D1、PNMAL2、CALM3、PTGIR、GNG8、DACT3、DACT3-AS1、PRKD2、MIR320E、STRN4、FKRP、SLC1A5、SNAR-E、AP2S1、ARHGAP35、NPAS1、TMEM160、ZC3H4、SAE1、BBC3、MIR3190、MIR3191、CCDC9、PRR24、C5AR1、GPR77、DHX34、MEIS3、SLC8A2、KPTN、NAPA-AS1、NAPA、ZNF541、GLTSCR1、EHD2、GLTSCR2、SNORD23、SEPW1、TPRX1、CRX、SULT2A1、SNAR-A12、SNAR-C5、SNAR-A1、SNAR-A3、SNAR-C2、SNAR-A2、SNAR-C4、SNAR-A13、SNAR-C3、SNAR-C1、BSPH1、ELSPBP1、CABP5、PLA2G4C、LOC100505754、LIG1、C19orf68、CARD8、LOC100505812、ZNF114、CCDC114、EMP3、TMEM143、SYNGR4、KDELR1、GRIN2D、GRWD1、KCNJ14、CYTH2、LMTK3、SULT2B1、FAM83E、SPACA4、RPL18、SPHK2、DBP、CA11、SEC1P、NTN5、FUT2、MAMSTR、RASIP1、IZUMO1、FUT1、FGF21、BCAT2、HSD17B14、PLEKHA4、PPP1R15A、TULP2、NUCB1、DHDH、BAX、FTL、GYS1、RUVBL2、LHB、CGB、SNAR-G2、CGB2、CGB1、SNAR-G1、CGB5、CGB8、CGB7、NTF4、KCNA7、SNRNP70、LIN7B、C19orf73、PPFIA3、HRC、TRPM4、SLC6A16、MIR4324、CD37、TEAD2、DKKL1、CCDC155、PTH2、LOC100507003、SLC17A7、PIH1D1、ALDH16A1、FLT3LG、RPL13A、SNORD32A、SNORD33、SNORD34、SNORD35A、RPS11、SNORD35B、MIR150、FCGRT、RCN3、NOSIP、PRRG2、PRR12、RRAS、SCAF1、IRF3、BCL2L12、PRMT1、MIR5088、ADM5、CPT1C、TSKS、AP2A1、FUZ、MED25、PTOV1-AS1、PTOV1、MIR4749、PNKP、AKT1S1、TBC1D17、MIR4750、IL4I1、NUP62、ATF5、MIR4751、SIGLEC11、SIGLEC16、VRK3、ZNF473、FLJ26850、SNAR-A4、SNAR-A14、SNAR-A5、SNAR-A6、SNAR-A7、SNAR-A8、SNAR-A9、SNAR-A10、SNAR-A11、SNAR-B1、SNAR-B2、SNAR-D、IZUMO2、MYH14、KCNC3、NAPSB、NAPSA、NR1H2、POLD1、SPIB、MYBPC2、FAM71E1、EMC10、LOC100506114、JOSD2、ASPDH、LRRC4B、SNAR-F、SYT3、C19orf81、SHANK1、CLEC11A、GPR32、ACPT、C19orf48、SNORD88B、SNORD88A、SNORD88C、MGC45922、KLK1、KLK15、KLK3、KLK2、KLKP1、KLK4、LOC390956、KLK5、KLK6、KLK7、KLK8、KLK9、KLK10、KLK11、
KLK12、KLK13、KLK14、CTU1、SIGLEC9、SIGLEC7、SIGLEC17P、CD33、SIGLECL1、IGLON5、VSIG10L、ETFB、CLDND2、NKG7、LIM2、LOC147646、SIGLEC10、LOC100129083、SIGLEC8、CEACAM18、SIGLEC12、SIGLEC6、ZNF175、FLJ30403、SIGLEC5、SIGLEC14、MIR99B、MIRLET7E、MIR125A、LINC00085、HAS1、FPR1、FPR2、FPR3、ZNF577、ZNF649、ZNF613、ZNF350、ZNF615、ZNF614、ZNF432、ZNF841、ZNF616、ZNF83、ZNF836、PPP2R1A、ZNF766、MIR643、ZNF480、ZNF610、ZNF880、ZNF528、ZNF534、ZNF578、ZNF808、ZNF701、ZNF137P、ZNF611、ZNF600、ZNF28、ZNF468、ZNF320、ZNF816-ZNF321P、ZNF321P、ZNF816、ZNF702P、ERVV-1、ERVV-2、ZNF160、ZNF415、ZNF347、ZNF665、ZNF677、VN1R2、VN1R4、FAM90A27P、BIRC8、ZNF845、ZNF525、ZNF765、TPM3P9、ZNF761、ZNF813、ZNF331、LOC284379、DPRX、MIR512-1、MIR512-2、MIR1323、MIR498、MIR520E、MIR515-1、MIR519E、MIR520F、MIR515-2、MIR519C、MIR1283-1、MIR520A、MIR526B、MIR519B、MIR525、MIR523、MIR518F、MIR520B、MIR518B、MIR526A1、MIR520C、MIR518C、MIR524、MIR517A、MIR519D、MIR521-2、MIR520D、MIR517B、MIR520G、MIR516B2、MIR526A2、MIR518E、MIR518A1、MIR518D、MIR516B1、MIR518A2、MIR517C、MIR520H、MIR521-1、MIR522、MIR519A1、MIR527、MIR516A1、MIR1283-2、MIR516A2、MIR519A2、MIR371A、MIR371B、MIR372、MIR373、NLRP12、MYADM、PRKCG、CACNG7、CACNG8、MIR935、CACNG6、VSTM1、TARM1、OSCAR、NDUFA3、TFPT、PRPF31、CNOT3、LENG1、TMC4、MBOAT7、TSEN34、RPS9、LILRB3、LILRA6、LILRB5、LILRB2、MIR4752、LILRA3、LILRA5、LILRA4、LAIR1、TTYH1、LENG8、LENG9、CDC42EP5、LAIR2、KIR3DX1、LILRA2、LILRA1、LILRB1、LILRB4、LILRP2、KIR3DL3、KIR2DL3、KIR2DL1、KIR2DL4、KIR3DL1、KIR2DS4、KIR3DL2、FCAR、NCR1、NLRP7、NLRP2、GP6、RDH13、EPS8L1、PPP1R12C、TNNT1、TNNI3、DNAAF3、SYT5、PTPRH、TMEM86B、PPP6R1、HSPBP1、BRSK1、TMEM150B、SUV420H2、COX6B2、FAM71E2、IL11、TMEM190、TMEM238、RPL28、UBE2S、SHISA7、ISOC2、ZNF628、NAT14、SSC5D、SBK2、SGK110、ZNF579、FIZ1、ZNF524、ZNF865、ZNF784、ZNF580、ZNF581、CCDC106、U2AF2、EPN1、NLRP9、RFPL4A、LOC729974、NLRP11、NLRP4、NLRP13、NLRP8、NLRP5、ZNF787、ZNF444、GALP、ZSCAN5B、ZSCAN5A、ZSCAN5D、LOC100506374、ZNF542、ZNF582、ZNF582-AS1、ZNF583、ZNF667、LOC100128252、ZNF471、ZFP28、ZNF470、ZNF71、LOC147670、ZNF835、ZIM2、PEG3、PEG3-AS1、MIMT1、USP29、ZIM3、DUXA、ZNF264、AURKC、ZNF805、LOC100996417、ZNF460、ZNF543、ZNF304、TRAPPC2P1、ZNF547、ZNF548、ZNF17、ZNF749、VN1R1、ZNF772、ZNF419、ZNF773、ZNF549、ZNF550、ZNF416、ZIK1、ZNF530、ZNF134、ZNF211、ZSCAN4、ZNF551、ZNF154、ZNF671、ZNF776、ZNF586、ZNF552、FKBP1AP1、ZNF587B、ZNF587、ZNF814、ZNF417、
ZNF418、ZNF256、C19orf18、ZNF606、LOC100128398、ZSCAN1、ZNF135、ZSCAN18、ZNF329、ZNF274、ZNF544、ZNF8、ZSCAN22、A1BG、A1BG-AS1、ZNF497、ZNF837、MIR4754、RPS5、LOC646862、LOC100506634、ZNF584、ZNF132、ZNF324B、ZNF324、ZNF446、SLC27A5、ZBTB45、TRIM28、CHMP2A、UBE2M、LOC100131691、MZF1、MGC2752、FAM110C、SH3YL1、ACP1、FAM150B、LOC727944、LOC100996637、TMEM18、LOC339822、SNTG2、TPO、PXDN、MYT1L、LOC730811、TSSC1、TRAPPC12、ADI1、LOC100506014、RNASEH1、LOC100506054、RPS7、COLEC11、ALLC、DCDC2C、LOC100505964、LOC100996394、LOC727982、SOX11、LOC150622、LOC400940、LOC100506216、LINC00487、CMPK2、RSAD2、RNF144A-AS1、RNF144A、LOC100506274、LOC339788、LINC00299、LOC100506299、LOC100996537、ID2、KIDINS220、MBOAT2、LOC100506317、ASAP2、ITGB1BP1、CPSF3、IAH1、ADAM17、YWHAQ、LOC100996549、TAF1B、GRHL1、KLF11、CYS1、RRM2、C2orf48、MIR4261、HPCAL1、ODC1、SNORA80B、LOC100996551、NOL10、ATP6V1C2、PDIA6、KCNF1、FLJ33534、C2orf50、PQLC3、ROCK2、LINC00570、E2F6、GREB1、MIR4429、NTSR2、LPIN1、LOC100506405、MIR548S、MIR4262、LOC100506457、MIR3681、TRIB2、MIR3125、LOC100506474、FAM84A、NBAS、DDX1、MYCNOS、MYCN、FAM49A、RAD51AP2、VSNL1、SMC6、GEN1、MSGN1、KCNS3、RDH14、NT5C1B-RDH14、NT5C1B、MIR4757、OSR1、FLJ12334、TTC32、WDR35、MATN3、LAPTM4A、SDC1、LOC100131373、PUM2、RHOB、HS1BP3、GDF7、C2orf43、APOB、LOC100507562、LOC645949、KLHL29、ATAD2B、UBXN2A、MFSD2B、C2orf44、FKBP1B、SF3B14、TP53I3、PFN4、FAM228B、FAM228A、ITSN2、LOC100507630、NCOA1、PTRHD1、CENPO、ADCY3、DNAJC27、DNAJC27-AS1、EFR3B、POMC、DNMT3A、MIR1301、LOC100131510、DTNB、ASXL2、KIF3C、RAB10、FAM59B、HADHA、HADHB、GPR113、EPT1、CCDC164、OTOF、C2orf70、CIB4、KCNK3、C2orf18、CENPA、DPYSL5、MAPRE3、TMEM214、AGBL5、OST4、EMILIN1、KHK、CGREF1、ABHD1、PREB、C2orf53、TCF23、SLC5A6、ATRAID、CAD、SLC30A3、DNAJC5G、TRIM54、UCN、MPV17、GTF3C2、LOC100505624、EIF2B4、SNX17、ZNF513、PPM1G、FTH1P3、NRBP1、KRTCAP3、IFT172、FNDC4、GCKR、C2orf16、ZNF512、CCDC121、GPN1、SUPT7L、SLC4A1AP、MRPL33、RBKS、BRE-AS1、BRE、MIR4263、LOC100505716、FLJ31356、FOSL2、PLB1、LOC100505774、PPP1CB、SPDYA、TRMT61B、WDR43、SNORD92、SNORD53、FAM179A、C2orf71、CLIP4、ALK、YPEL5、LBH、LCLAT1、CAPN13、GALNT14、LOC100652774、CAPN14、EHD3、XDH、SRD5A2、MEMO1、DPY30、HP11026、SPAST、SLC30A6、NLRC4、YIPF4、BIRC6、MIR558、TTC27、MIR4765、LINC00486、LOC100271832、LTBP1、MIR4430、RASGRP3、FAM98A、MYADML、MIR548AD、LOC100288911、CRIM1、FEZ2、VIT、STRN、HEATR5B、CCDC75、EIF2AK2、SULT6B1、
LOC100505876、CEBPZ、NDUFAF7、PRKD3、QPCT、CDC42EP3、FAM82A1、CYP1B1、CYP1B1-AS1、ATL2、HNRPLL、GALM、SRSF7、GEMIN6、DHX57、MORN2、ARHGEF33、LOC375196、SOS1、CDKL4、MAP4K3、LOC728730、TMEM178A、THUMPD2、SLC8A1-AS1、SLC8A1、LOC388942、C2orf91、PKDCC、EML4、COX7A2L、KCNG3、LOC100130921、MTA3、OXER1、HAAO、LOC100506047、ZFP36L2、LOC100129726、THADA、PLEKHH2、LOC728819、DYNC2LI1、ABCG5、ABCG8、LRPPRC、PPM1B、SLC3A1、PREPL、CAMKMT、LOC100130502、LOC100506088、SIX3-AS1、SIX3、SIX2、UNQ6975、SRBD1、PRKCE、EPAS1、TMEM247、ATP6V1E2、RHOQ、PIGF、CRIPT、SOCS5、LOC388948、LOC100134259、MCFD2、TTC7A、C2orf61、CALM2、BCYRN1、EPCAM、MIR559、MSH2、KCNK12、MSH6、FBXO11、LOC100506235、FOXN2、PPP1R21、STON1-GTF2A1L、STON1、GTF2A1L、LHCGR、FSHR、NRXN1、LOC100506300、MIR4431、ASB3、GPR75-ASB3、CHAC2、ERLEC1、MIR3682、GPR75、PSME4、ACYP2、TSPYL6、C2orf73、SPTBN1、RPL23AP32、EML6、RTN4、CLHC1、RPS27A、MTIF2、PRORSD1P、CCDC88A、CCDC104、SMEK2、PNPT1、EFEMP1、MIR217、MIR216A、MIR216B、CCDC85A、VRK2、FANCL、FLJ30838、MIR4432、LOC100506891、BCL11A、LOC100506934、PAPOLG、FLJ16341、REL、PUS10、PEX13、KIAA1841、LOC339803、C2orf74、AHSA2、USP34、SNORA70B、XPO1、FAM161A、CCT4、COMMD1、B3GNT2、MIR5192、TMEM17、EHBP1、LOC100132215、OTX1、DBIL5P2、WDPCP、MDH1、UGP2、VPS54、PELI1、LINC00309、MIR4433、LGALSL、AFTPH、MIR4434、LOC339807、SERTAD2、LOC400958、SLC1A4、CEP68、RAB1A、ACTR2、SPRED2、MIR4778、MEIS1-AS3、MEIS1、LOC100507073、LOC644838、ETAA1、C1D、WDR92、PNO1、PPP3R1、CNRIP1、PLEK、FBXO48、APLF、PROKR1、ARHGAP25、LOC100996448、BMP10、GKN2、GKN1、ANTXR1、MIR3126、GFPT1、NFU1、AAK1、SNORA36C、ANXA4、GMCL1、SNRNP27、MXD1、ASPRV1、PCBP1-AS1、PCBP1、LOC100133985、C2orf42、TIA1、MIR1285-2、PCYOX1、SNRPG、FAM136A、TGFA、ADD2、FIGLA、CLEC4F、CD207、VAX2、ATP6V1B1、ANKRD53、TEX261、OR7E91P、NAGK、MCEE、MPHOSPH10、PAIP2B、ZNF638、ZNF638-IT1、DYSF、CYP26B1、EXOC6B、SPR、EMX1、SFXN5、RAB11FIP5、NOTO、SMYD5、PRADC1、CCT7、FBXO41、EGR4、ALMS1、NAT8、ALMS1P、NAT8B、TPRKB、DUSP11、C2orf78、STAMBP、LOC100652991、ACTG2、DGUOK、DGUOK-AS1、TET3、BOLA3、BOLA3-AS1、MOB1A、MTHFD2、SLC4A5、DCTN1、DCTN1-AS1、C2orf81、WDR54、RTKN、INO80B-WBP1、INO80B、WBP1、MOGS、MRPL53、CCDC142、TTC31、LBX2、LBX2-AS1、PCGF1、TLX2、DQX1、AUP1、HTRA2、LOXL3、DOK1、C2orf65、SEMA4F、HK2、POLE4、TACR1、MIR5000、EVA1A、MRPL19、GCFC2、LRRTM4、SNAR-H、REG3G、REG1B、REG1A、REG1P、REG3A、CTNNA2、MIR4264、LRRTM1、LOC100507201、LOC1720、FUNDC2P2、
SUCLG1、DNAH6、TRABD2A、TMSB10、KCMF1、LOC100996478、TCF7L1、TGOLN2、RETSAT、ELMOD3、CAPG、SH2D6、LOC100630918、MAT2A、GGCX、VAMP8、VAMP5、RNF181、TMEM150A、USP39、C2orf68、SFTPB、GNLY、ATOH8、LOC284950、ST3GAL5、LOC90784、POLR1A、PTCD3、SNORD94、IMMT、MIR4779、MRPL35、REEP1、KDM3A、CHMP3、RNF103-CHMP3、RNF103、RMND5A、CD8A、CD8B、ANAPC1P1、RGPD1、PLGLB1、LOC285074、MIR4771-1、LINC00152、MIR4435-1、LOC730268、PLGLB2、RGPD2、KRCC1、SMYD1、MIR4780、FABP1、THNSL2、FOXI3、TEX37、EIF2AK3、RPIA、ANKRD36BP2、MIR4436A、LOC654342、LOC100506191、GGT8P、ACTR3BP2、LOC90499、ANKRD20A8P、LOC442028、TEKT4、MAL、MRPS5、ZNF514、ZNF2、PROM2、KCNIP3、FAHD2A、TRIM43B、TRIM43、LINC00342、FAHD2CP、GPAT2、ADRA2B、ASTL、DUSP2、STARD7、LOC285033、TMEM127、CIAO1、SNRNP200、ITPRIPL1、NCAPH、NEURL3、ARID5A、LOC100996535、KANSL3、FER1L5、LMAN2L、CNNM4、MIR3127、LOC100506036、CNNM3、ANKRD23、ANKRD39、SEMA4C、FAM178B、FAHD2B、ANKRD36、LOC100506076、LOC100506123、ANKRD36B、COX5B、ACTR1B、LOC728537、ZAP70、TMEM131、VWA3B、CNGA3、INPP4A、COA5、UNC50、MGAT4A、KIAA1211L、TSGA10、C2orf15、LIPT1、MITD1、MRPL30、LYG2、LYG1、TXNDC9、EIF5B、REV1、AFF3、LOC150577、LONRF2、CHST10、NMS、PDCL3、NPAS2、RPL31、TBC1D8、LOC100506286、C2orf29、SNORD89、RNF149、MIR5696、CREG2、RFX8、MAP4K4、LOC100506328、IL1R2、LOC100131131、IL1R1、IL1RL2、IL1RL1、IL18R1、IL18RAP、MIR4772、SLC9A4、SLC9A2、MFSD9、TMEM182、LOC100287010、LOC150568、LOC284998、LOC100506421、POU3F3、LOC100128131、MRPS9、GPR45、TGFBRAP1、LOC100506473、C2orf49、FHL2、LOC285000、NCK2、C2orf40、UXS1、PLGLA、RGPD3、ST6GAL2、LOC729121、RGPD4、SLC5A7、SULT1C3、SULT1C2、SULT1C2P1、SULT1C4、GCC2、LIMS1、RANBP2、CCDC138、EDAR、SH3RF3-AS1、SH3RF3、MIR4265、MIR4266、LOC729164、SEPT10、SOWAHC、LOC100506563、RGPD5、LIMS3、LIMS3-LOC440895、LOC440895、LOC440894、MIR4267、MALL、MIR4436B1、NPHP1、LINC00116、LOC100507334、MIR4436B2、LOC151009、LOC100288570、LIMS3L、RGPD6、LOC100507581、BUB1、ACOXL、FLJ44006、BCL2L11、LOC100505634、LOC100128130、MIR4435-2、LOC541471、ANAPC1、MIR4771-2、MERTK、TMEM87B、FBLN7、ZC3H8、ZC3H6、RGPD8、TTL、POLR1B、CHCHD5、FLJ42351、SLC20A1、CKAP2L、IL1A、IL1B、IL37、IL36G、IL36A、IL36B、IL36RN、IL1F10、IL1RN、PSD4、PAX8、LOC654433、CBWD2、FOXD4L1、FAM138B、MIR1302-3、WASH2P、DDX11L2、RPL23AP7、RABL2A、LOC100506748、SLC35F5、MIR4782、ACTR3、LOC100499194、LOC440900、DPP10、LOC389023、DDX18、CCDC93、INSIG2、LOC100506797、EN1、MARCO、C1QL2、
STEAP3、C2orf76、DBI、TMEM37、SCTR、PCDP1、TMEM177、PTPN4、EPB41L5、TMEM185B、RALB、INHBB、LOC84931、GLI2、TFCP2L1、CLASP1、RNU4ATAC、LOC254128、MKI67IP、TSN、CNTNAP5、GYPC、LOC339760、BIN1、CYP27C1、ERCC3、MAP3K2、LOC100506922、PROC、MIR4783、LOC100131492、IWS1、MYO7B、LIMS2、GPR17、SFT2D3、WDR33、POLR2D、AMMECR1L、SAP130、UGGT1、HS6ST1、LOC151121、LOC389033、LOC100131320、RAB6C、LOC440905、POTEF、CCDC74B-AS1、CCDC74B、SMPD4、MZT2B、TUBA3E、CCDC115、IMP4、PTPN18、LOC100216479、CYP4F43P、POTEI、CFC1B、LOC646743、TISP43、CFC1、POTEJ、CYP4F30P、LOC100288897、GPR148、FAM123C、ARHGEF4、FAM168B、PLEKHB2、POTEE、LOC440910、WTH3DI、LOC389043、LOC401010、TUBA3D、MZT2A、MIR4784、LOC150776、CCDC74A、POTEKP、LOC100507474、LOC100507460、C2orf27A、C2orf27B、ANKRD30BL、MIR663B、ZNF806、AZFP、FAM201B、GPR39、LYPD1、NCKAP5、LOC100996685、MIR3679、MGAT5、TMEM163、ACMSD、MIR5590、LOC100129961、CCNT2、MAP3K19、RAB3GAP1、ZRANB3、R3HDM1、MIR128-1、UBXN4、LCT、LOC100507600、MCM6、DARS、CXCR4、THSD7B、HNMT、SPOPL、NXPH2、LOC647012、LRP1B、KYNU、ARHGAP15、GTDC1、ZEB2、ZEB2-AS1、DKFZp686O1327、LOC100505498、PABPC1P2、ACVR2A、ORC4、MBD5、EPC2、KIF5C、LYPD6B、LYPD6、MMADHC、FLJ32955、RND3、RBM43、NMI、TNFAIP6、MIR4773-1、MIR4773-2、RIF1、NEB、ARL5A、CACNB4、STAM2、FMNL2、PRPF40A、ARL6IP6、RPRM、GALNT13、LOC100144595、KCNJ3、NR4A2、GPD2、GALNT5、ERMN、FAM133DP、CYTIP、ACVR1C、ACVR1、UPP2、CCDC148-AS1、CCDC148、PKP4、DAPL1、TANC1、WDSUB1、BAZ2B、MARCH7、LY75-CD302、CD302、LY75、PLA2R1、ITGB6、RBMS1、MIR4785、TANK、LOC100996579、PSMD14、TBR1、SLC4A10、DPP4、GCG、FAP、IFIH1、GCA、KCNH7、FIGN、GRB14、COBLL1、SNORA70F、SLC38A11、SCN3A、SCN2A、CSRNP3、GALNT3、LOC100506124、TTC21B、LOC100506134、SCN1A、SCN9A、SCN7A、XIRP2、B3GALT1、STK39、CERS6、MIR4774、CERS6-AS1、NOSTRIN、SPC25、G6PC2、ABCB11、DHRS9、LRP2、BBS5、KBTBD10、FASTKD1、PPIG、CCDC173、PHOSPHO2、PHOSPHO2-KLHL23、KLHL23、SSB、METTL5、UBR3、MYO3B、LOC440925、SP5、LOC100505695、ERICH2、GAD1、GORASP2、TLK1、METTL8、DCAF17、CYBRD1、DYNC1I2、SLC25A12、HAT1、METAP1D、DLX1、DLX2、ITGA6、PDK1、RAPGEF4-AS1、RAPGEF4、ZAK、MLK7-AS1、CDCA7、SP3、LOC100128905、OLA1、LOC285084、SP9、CIR1、SCRN3、GPR155、WIPF1、H3F3AP4、CHRNA1、CHN1、ATF2、MIR933、ATP5G3、KIAA1715、EVX2、HOXD13、HOXD12、HOXD11、HOXD10、HOXD9、HOXD8、HOXD-AS2、MIR10B、HOXD4、HOXD3、HOXD-AS1、HOXD1、MTX2、MIR1246、LOC375295、HNRNPA3、MIR4444-1、NFE2L2、MIR3128、LOC100130691、AGPS、TTC30B、TTC30A、
PDE11A、RBM45、OSBPL6、PRKRA、DFNB59、FKBP7、PLEKHA3、TTN-AS1、TTN、CCDC141、SESTD1、ZNF385B、MIR1258、CWC22、UBE2E3、MIR4437、ITGA4、CERKL、NEUROD1、SSFA2、PPP1R1C、PDE1A、DNAJC10、FRZB、NCKAP1、DUSP19、NUP35、MIR548AE1、ZNF804A、LOC100506923、FSIP2、ZC3H15、ITGAV、FAM171B、ZSWIM2、CALCRL、TFPI、GULP1、MIR561、DIRC1、COL3A1、MIR1245A、MIR1245B、MIR3606、COL5A2、MIR3129、WDR75、SLC40A1、ASNSD1、ANKAR、OSGEPL1、ORMDL1、PMS1、MSTN、C2orf88、HIBCH、INPP1、MFSD6、TMEM194B、NAB1、GLS、STAT1、STAT4、MYO1B、NABP1、SDPR、TMEFF2、LOC100506993、PCGEM1、SLC39A10、DNAH7、STK17B、HECW2、CCDC150、LOC100130452、GTF3C3、C2orf66、PGAP1、ANKRD44、SF3B1、COQ10B、HSPD1、HSPE1、HSPE1-MOB4、MOB4、RFTN2、MARS2、BOLL、PLCL1、SATB2、SATB2-AS1、FONG、C2orf69、TYW5、C2orf47、SPATS2L、KCTD18、SGOL2、AOX1、AOX2P、LOC100507140、BZW1、RNU6-6、CLK1、PPIL3、NIF3L1、ORC2、FAM126B、NDUFB3、CFLAR、CFLAR-AS1、CASP10、CASP8、ALS2CR12、TRAK2、STRADB、ALS2CR11、TMEM237、MPP4、ALS2、CDK15、FZD7、LOC100652824、LOC729224、SUMO1、NOP58、SNORD70、SNORD11B、SNORD11、BMPR2、FAM117B、ICA1L、WDR12、ALS2CR8、NBEAL1、CYP20A1、ABI2、RAPH1、CD28、CTLA4、ICOS、PARD3B、NRP2、INO80D、GCSHP3、NDUFS1、EEF1B2、SNORD51、SNORA41、GPR1、ZDBF2、ADAM23、LOC200726、DYTN、MDH1B、FASTKD2、MIR3130-2、MIR3130-1、CPO、KLF7、MIR2355、MIR1302-4、CREB1、METTL21A、CCNYL1、MIR4775、FZD5、PLEKHM3、LOC100507443、CRYGD、CRYGC、CRYGB、CRYGA、C2orf80、IDH1、IDH1-AS1、PIKFYVE、PTH2R、MAP2、UNC80、RPE、KANSL1L、ACADL、MYL1、LANCL1、CPS1、CPS1-IT1、ERBB4、MIR548F2、MIR4776-1、MIR4776-2、IKZF2、LOC100130451、SPAG16、MIR4438、VWC2L、VWC2L-IT1、BARD1、ABCA12、ATIC、FN1、LINC00607、MREG、PECR、TMEM169、XRCC5、PKI55、MARCH4、SMARCAL1、LOC100507554、RPL37A、IGFBP2、IGFBP5、TNP1、DIRC3、TNS1、RUFY4、CXCR2P1、CXCR2、CXCR1、ARPC2、GPBAR1、AAMP、PNKD、TMBIM1、C2orf62、SLC11A1、CTDSP1、MIR26B、VIL1、USP37、RQCD1、PLCD4、ZNF142、BCS1L、RNF25、STK36、TTLL4、CYP27A1、PRKAG3、WNT6、WNT10A、CDK5R2、LINC00608、FEV、CRYBA2、MIR375、LOC100129175、CCDC108、IHH、MIR3131、NHEJ1、SLC23A3、CNPPD1、FAM134A、ZFAND2B、ABCB6、ATG9A、ANKZF1、GLB1L、STK16、TUBA4A、TUBA4B、DNAJB2、PTPRN、MIR153-1、RESP18、DNPEP、DES、SPEG、LOC100996693、GMPPA、ASIC4、CHPF、TMEM198、MIR3132、OBSL1、INHA、STK11IP、SLC4A3、MIR4268、EPHA4、LOC729770、PAX3、CCDC140、LOC440934、SGPP2、FARSB、MOGAT1、ACSL3、KCNE4、SCG2、AP1S3、WDFY1、MRPL44、SERPINE2、FAM124B、CUL3、DOCK10、MIR4439、NYAP2、LOC646736、MIR5702、IRS1、
HBDD1、COL4A4、COL4A3、MFF、TM4SF20、MIR5703、AGFG1、C2orf83、SLC19A3、CCL20、WDR69、SPHKAP、PID1、DNER、TRIP12、FBXO36、SLC16A14、SP110、SP140、SP140L、SP100、LOC151475、CAB39、ITM2C、LOC151484、GPR55、LOC348761、SPATA3、C2orf72、PSMD1、HTR2B、ARMC9、MIR4777、B3GNT7、NCL、LOC100996253、SNORA75、SNORD20、SNORD82、LINC00471、NMUR1、C2orf57、PTMA、MIR1244-1、PDE6D、COPS7B、MIR1471、NPPC、DIS3L2、MIR562、ALPP、ECEL1P2、ALPPL2、ALPI、ECEL1、PRSS56、CHRND、CHRNG、TIGD1、MIR5001、EIF4E2、EFHD1、GIGYF2、KCNJ13、C2orf82、NGEF、NEU2、INPP5D、ATG16L1、SCARNA5、SCARNA6、SAG、DGKD、USP40、UGT1A8、UGT1A10、UGT1A9、UGT1A7、UGT1A6、UGT1A5、UGT1A4、UGT1A3、DNAJB3、LOC100286922、UGT1A1、HEATR7B1、HJURP、MSL3P1、TRPM8、SPP2、ARL4C、SH3BP4、AGAP1、AGAP1-IT1、GBX2、ASB18、IQCA1、CXCR7、LOC93463、COPS8、COL6A3、MLPH、PRLH、RAB17、LRRFIP1、RBM44、RAMP1、UBE2F、UBE2F-SCLY、SCLY、ESPNL、KLHL30、FAM132B、LOC100996584、ILKAP、LOC151174、LOC643387、HES6、PER2、TRAF3IP1、ASB1、LOC151171、LOC100287387、TWIST2、FLJ43879、HDAC4、MIR4440、MIR4441、MGC16025、MIR4269、LOC100128563、MIR2467、FLJ45964、LOC150935、MIR4786、NDUFA10、OR6B2、PRR21、OR6B3、MYEOV2、OTOS、GPC1、PP14571、MIR149、ANKMY1、DUSP28、RNPEPL1、CAPN10、GPR35、AQP12B、AQP12A、KIF1A、AGXT、C2orf54、LOC728763、LOC200772、LOC728208、SNED1、MTERFD2、PASK、PPP1R7、ANO7、HDLBP、SEPT2、FARP2、MIR3133、STK25、BOK-AS1、BOK、THAP4、ATG4B、DTYMK、ING5、D2HGDH、GAL3ST2、NEU4、PDCD1、CXXC11、FLJ38379、LOC100996616、LOC728323、DEFB125、DEFB126、DEFB127、DEFB128、DEFB129、DEFB132、C20orf96、ZCCHC3、LOC100507459、SOX12、NRSN2、TRIB3、RBCK1、TBC1D20、CSNK2A1、TCF15、SRXN1、SCRT2、SLC52A3、FAM110A、ANGPT4、RSPO4、PSMF1、TMEM74B、C20orf202、RAD21L1、SNPH、SDCBP2、FKBP1A-SDCBP2、SDCBP2-AS1、FKBP1A、NSFL1C、SIRPB2、SIRPD、SIRPB1、SIRPG、LOC100289473、SIRPA、PDYN、STK35、LOC388780、TGM3、TGM6、SNRPB、SNORD119、ZNF343、TMC2、NOP56、MIR1292、SNORD110、SNORA51、SNORD86、SNORD56、SNORD57、IDH3B、EBF4、CPXM1、C20orf141、TMEM239、PCED1A、VPS16、PTPRA、GNRH2、MRPS26、OXT、AVP、UBOX5-AS1、UBOX5、FASTKD5、PROSAPIP1、DDRGK1、ITPA、SLC4A11、C20orf194、ATRN、GFRA4、ADAM33、SIGLEC1、HSPA12B、C20orf27、SPEF1、CENPB、CDC25B、AP5S1、MAVS、PANK2、MIR103A2、MIR103B2、RNF24、SMOX、LOC728228、ADRA1D、PRNP、PRND、PRNT、RASSF2、SLC23A2、TMEM230、PCNA、PCNA-AS1、CDS2、PROKR2、LINC00658、LOC643406、LINC00654、GPCPD1、C20orf196、CHGB、TRMT6、MCM8、CRLS1、LRRN4、FERMT1、BMP2、HAO1、TMX4、PLCB1、RNU105B、PLCB4、
LAMP5、PAK7、SNAP25-AS1、ANKRD5、SNAP25、MKKS、SLX4IP、JAG1、LOC339593、LINC00687、BTBD3、LOC100996658、LOC100505515、SPTLC3、ISM1、ISM1-AS1、TASP1、ESF1、NDUFAF5、SEL1L2、MACROD2、FLRT3、MACROD2-AS1、KIF16B、SNRPB2、OTOR、PCSK2、BFSP1、DSTN、RRBP1、BANF2、SNX5、SNORD17、C20orf72、LOC100996673、OVOL2、PET117、CSRP2BP、ZNF133、DZANK1-AS1、DZANK1、POLR3F、MIR3192、RBBP9、SEC23B、LINC00493、DTD1、LINC00652、LOC100270804、C20orf78、SCP2D1、SLC24A3、LOC100130264、LOC100287166、RIN2、NAA20、CRNKL1、C20orf26、INSM1、RALGAPA2、PLK1S1、XRN2、NKX2-4、NKX2-2、PAX1、LOC100652902、LOC100270679、LOC100505651、LOC284788、LINC00261、FOXA2、SSTR4、THBD、CD93、LINC00656、LOC100505664、NXT1、LOC100505683、GZF1、NAPB、CSTL1、CST11、CST8、CST13P、CST9L、CST9、CST3、CST4、CST1、CST2、CST5、GGTLC1、FLJ33581、SYNDIG1、CST7、APMAP、ACSS1、VSX1、LOC284798、ENTPD6、PYGB、ABHD12、GINS1、NINL、NANP、ZNF337、FAM182B、LOC100289375、LOC100134868、FAM182A、NCOR1P1、LOC284801、MIR663A、FLJ45832、FRG1B、MLLT10P1、DEFB115、DEFB116、DEFB118、DEFB119、DEFB121、DEFB122、DEFB123、DEFB124、REM1、LINC00028、HM13、PSIMCT-1、HM13-AS1、ID1、MIR3193、COX4I2、BCL2L1、TPX2、MYLK2、FOXS1、DUSP15、TTLL9、PDRG1、XKR7、CCM2L、HCK、TM9SF4、TSPY26P、PLAGL2、POFUT1、MIR1825、KIF3B、ASXL1、C20orf112、LOC149950、C20orf203、COMMD7、DNMT3B、MAPRE1、EFCAB8、SUN5、BPIFB2、BPIFB6、BPIFB3、BPIFB4、BPIFA2、BPIFA4P、BPIFA3、BPIFA1、BPIFB1、CDK5RAP1、SNTA1、CBFA2T2、NECAB3、C20orf144、ACTL10、E2F1、PXMP4、ZNF341、CHMP4B、RALY、MIR4755、EIF2S2、ASIP、AHCY、ITCH、MIR644A、DYNLRB1、MAP1LC3A、PIGU、TP53INP2、NCOA6、HMGB3P1、GGT7、ACSS2、GSS、MYH7B、MIR499A、MIR499B、TRPC4AP、EDEM2、PROCR、MMP24、EIF6、FAM83C、UQCC、GDF5OS、GDF5、MIR1289-1、CEP250、C20orf173、ERGIC3、FER1L4、SPAG4、CPNE1、RBM12、NFS1、ROMO1、RBM39、PHF20、SCAND1、CNBD2、LINC00657、EPB41L1、AAR2、DLGAP4、MYL9、TGIF2、TGIF2-C20ORF24、C20orf24、SLA2、NDRG3、DSN1、SOGA1、C20orf118、SAMHD1、RBL1、C20orf132、RPN2、GHRH、MANBAL、SRC、BLCAP、NNAT、LINC00489、LOC100287792、CTNNBL1、VSTM2L、TTI1、RPRD1B、TGM2、KIAA1755、BPI、LBP、LOC388796、SNORA71B、SNORA71A、SNORA71C、SNORA71D、SNHG11、SNORA39、SNORA60、RALGAPB、MIR548O2、ADIG、ARHGAP40、SLC32A1、ACTR5、PPP1R16B、FAM83D、DHX35、LOC339568、LOC100505663、MAFB、LOC100128988、TOP1、LOC100996518、PLCG1、ZHX3、LPIN3、EMILIN3、CHD6、PTPRT、SRSF6、L3MBTL1、SGK2、IFT52、MYBL2、GTSF1L、TOX2、JPH2、C20orf111、LOC100505783、GDAP1L1、FITM2、R3HDML、HNF4A、
MIR3646、TTPAL、SERINC3、PKIG、ADA、LOC79015、WISP2、KCNK15、RIMS4、YWHAB、PABPC1L、TOMM34、STK4-AS1、STK4、KCNS1、WFDC5、WFDC12、PI3、SEMG1、SEMG2、SLPI、MATN4、RBPJL、SDC4、SYS1、SYS1-DBNDD2、TP53TG5、DBNDD2、PIGT、LOC100130157、WFDC2、SPINT3、WFDC6、EPPIN-WFDC6、EPPIN、WFDC8、WFDC9、WFDC10A、WFDC11、WFDC10B、WFDC13、MIR3617、SPINT4、WFDC3、DNTTIP1、UBE2C、TNNC2、SNX21、ACOT8、ZSWIM3、ZSWIM1、SPATA25、NEURL2、CTSA、PLTP、PCIF1、ZNF335、MMP9、LOC100128028、SLC12A5、NCOA5、CD40、CDH22、SLC35C2、ELMO2、ZNF663、MKRN7P、ZNF334、OCSTAMP、SLC13A3、TP53RK、SLC2A10、EYA2、MIR3616、ZMYND8、LOC100131496、NCOA3、SULF2、LOC100505983、LOC100506053、LINC00494、LOC100506069、PREX1、ARFGEF2、CSE1L、STAU1、DDX27、ZNFX1、ZNFX1-AS1、SNORD12C、SNORD12B、SNORD12、KCNB1、PTGIS、LOC728671、B4GALT5、SLC9A8、SPATA2、RNF114、SNAI1、LINC00651、UBE2V1、TMEM189-UBE2V1、TMEM189、CEBPB、LOC100506115、LOC284751、PTPN1、MIR645、FAM65C、MIR1302-5、LOC100506175、PARD6B、BCAS4、ADNP、DPM1、MOCS3、KCNG1、NFATC2、MIR3194、ATP9A、SALL4、ZFP64、TSHZ2、ZNF217、SUMO1P1、BCAS1、MIR4756、CYP24A1、PFDN4、DOK5、CBLN4、MC3R、FAM210B、AURKA、CSTF1、CASS4、RTFDC1、GCNT7、LOC100130156、FAM209A、FAM209B、TFAP2C、BMP7、MIR4325、SPO11、RAE1、MTRNR2L3、LOC100291105、RBM38、CTCFL、PCK1、ZBP1、PMEPA1、MIR4532、LOC100996602、C20orf85、ANKRD60、PPP4R1L、RAB22A、VAPB、APCDD1L、APCDD1L-AS1、MGC4294、STX16、STX16-NPEPL1、NPEPL1、LOC100652930、LOC100506348、MIR296、MIR298、GNAS-AS1、GNAS、TH1L、CTSZ、TUBB1、SLMO2-ATP5E、ATP5E、SLMO2、ZNF831、EDN3、PHACTR3、LOC100506384、SYCP2、FAM217B、PPP1R3D、CDH26、C20orf197、LOC729296、LOC284757、MIR646、MIR4533、MIR548AG2、LOC100506470、CDH4、LOC100128310、MIR1257、TAF4、LSM14B、PSMA7、SS18L1、GTPBP5、HRH3、FLJ44790、OSBPL2、ADRM1、LAMA5、MIR4758、RPS21、CABLES2、RBBP8NL、GATA5、C20orf166-AS1、C20orf166、MIR1-1、MIR133A2、LOC100131174、LOC100505735、SLCO4A1、LOC100127888、NTSR1、LINC00659、MRGBP、OGFR、COL9A3、TCFL5、DPH3P1、DIDO1、GID8、SLC17A9、BHLHE23、LOC63930、LINC00029、LOC100144597、HAR1B、HAR1A、MIR124-3、YTHDF1、BIRC7、MIR3196、NKAIN4、FLJ16779、ARFGAP1、MIR4326、COL20A1、CHRNA4、KCNQ2、EEF1A2、PPDPF、PTK6、SRMS、C20orf195、HELZ2、GMEB2、LOC100505771、STMN3、RTEL1、RTEL1-TNFRSF6B、TNFRSF6B、ARFRP1、ZGPAT、LIME1、SLC2A4RG、ZBTB46、C20orf181、ABHD16B、TPD52L2、DNAJC5、MIR941-1、MIR941-2、MIR941-3、MIR941-4、UCKL1、MIR1914、MIR647、UCKL1-AS1、ZNF512B、SAMD10、PRPF6、LINC00176、SOX18、TCEA2、RGS19、
OPRL1、C20orf201、NPBWR2、MYT1、PCMTD2、LINC00266-1、MIR3648、MIR3687、TEKT4P2、TPTE、BAGE2、ANKRD30BP2、MIR3156-3、POTED、MIR3118-5、LOC441956、C21orf15、ANKRD20A11P、LIPI、RBM11、ABCC13、HSPA13、SAMSN1、SAMSN1-AS1、LOC388813、NRIP1、USP25、LINC00478、MIR99A、MIRLET7C、MIR125B2、C21orf37、CXADR、BTG3、C21orf91-OT1、C21orf91、CHODL-AS1、CHODL、TMPRSS15、MIR548X、LOC100505973、LINC00320、NCAM2、LINC00317、LINC00308、D21 S2088E、LOC339622、LINC00158、MIR155HG、MIR155、LINC00515、MRPL39、JAM2、ATP5J、GABPA、APP、LOC100996571、CYYR1、ADAMTS1、ADAMTS5、MIR4759、LINC00113、LINC00314、LINC00161、N6AMT1、LTN1、RWDD2B、USP16、CCT8、C21orf7、LINC00189、BACH1、GRIK1、GRIK1-AS2、GRIK1-AS1、CLDN17、LINC00307、CLDN8、KRTAP24-1、KRTAP25-1、KRTAP26-1、KRTAP27-1、KRTAP23-1、KRTAP13-2、MIR4327、KRTAP13-1、KRTAP13-3、KRTAP13-4、KRTAP15-1、KRTAP19-1、KRTAP19-2、KRTAP19-3、KRTAP19-4、KRTAP19-5、KRTAP19-6、KRTAP19-7、KRTAP22-2、KRTAP6-3、KRTAP6-2、KRTAP22-1、KRTAP6-1、KRTAP20-1、KRTAP20-4、KRTAP20-2、KRTAP20-3、KRTAP21-3、KRTAP21-2、KRTAP21-1、KRTAP8-1、KRTAP7-1、KRTAP11-1、KRTAP19-8、TIAM1、LOC150051、SOD1、SCAF4、HUNK、LINC00159、MIS18A、MRAP、URB1、SNORA80、C21orf119、EVA1C、TCP10L、C21orf59、SYNJ1、GCFC1-AS1、GCFC1、C21orf49、C21orf62、OLIG2、OLIG1、C21orf54、IFNAR2、LOC100288432、IL10RB、IFNAR1、IFNGR2、TMEM50B、DNAJC28、GART、SON、DONSON、CRYZL1、ITSN1、ATP5O、LINC00649、LINC00650、MRPS6、SLC5A3、LINC00310、KCNE2、FAM165B、LOC388820、KCNE1、RCAN1、LOC100506369、CLIC6、LINC00160、LOC100506385、RUNX1、RUNX1-IT1、LOC100506403、MIR802、LOC100996609、SETD4、LOC100133286、CBR1、CBR3-AS1、CBR3、DOPEY2、MORC3、CHAF1B、CLDN14、SIM2、HLCS、DSCR6、PIGP、TTC3、DSCR9、DSCR3、DYRK1A、KCNJ6、DSCR4、DSCR8、DSCR10、KCNJ15、ERG、LINC00114、ETS2、FLJ45139、PSMG1、BRWD1、BRWD1-IT2、BRWD1-AS1、HMGN1、WRB、LCA5L、SH3BGR、C21orf88、B3GALT5、IGSF5、PCP4、DSCAM、MIR4760、DSCAM-AS1、DSCAM-IT1、LINC00323、MIR3197、BACE2、PLAC4、FAM3B、MX2、MX1、TMPRSS2、LINC00111、LINC00479、LINC00112、RIPK4、PRDM15、C2CD2、ZNF295、ZNF295-AS1、UMODL1、C21orf128、ABCG1、TFF3、TFF2、TFF1、TMPRSS3、UBASH3A、RSPH1、SLC37A1、PDE9A、WDR4、NDUFV3、MIR5692B、PKNOX1、CBS、U2AF1、LOC100288336、CRYAA、LINC00322、FLJ41733、SIK1、LINC00319、LINC00313、HSF2BP、RRP1B、PDXK、CSTB、RRP1、LOC284837、AGPAT3、TRAPPC10、PWP2、C21orf33、ICOSLG、DNMT3L、AIRE、PFKL、C21orf2、TRPM2、LRRC3-AS1、LRRC3、LRRC3DN、LOC100505727、TSPEAR、C21orf90、KRTAP10-1、
KRTAP10-2、KRTAP10-3、KRTAP10-4、KRTAP10-5、KRTAP10-6、KRTAP10-7、KRTAP10-8、KRTAP10-9、KRTAP10-10、KRTAP10-11、KRTAP12-4、KRTAP12-3、KRTAP12-2、KRTAP12-1、KRTAP10-12、UBE2G2、SUMO3、PTTG1IP、ITGB2、ITGB2-AS1、C21orf67、FAM207A、LINC00163、LINC00162、SSR4P1、ADARB1、POFUT2、LOC642852、LINC00315、LINC00316、LOC100505827、COL18A1、COL18A1-AS2、COL18A1-AS1、SLC19A1、LOC100129027、PCBP3、COL6A1、COL6A2、FTCD、SPATC1L、LSS、MCM3AP-AS1、MCM3AP、YBEY、C21orf58、PCNT、DIP2A、DIP2A-IT1、S100B、PRMT2、LOC400879、POTEH、OR11H1、CCT8L2、TPTEP1、ANKRD62P1-PARP4P3、XKR3、HSFY1P1、GAB4、CECR7、IL17RA、CECR6、LOC100996342、CECR5、CECR5-AS1、CECR1、CECR3、CECR2、SLC25A18、ATP6V1E1、BCL2L13、BID、MIR3198-1、LINC00528、MICAL3、MIR648、FLJ41941、PEX26、TUBA8、USP18、LOC642643、GGT3P、LOC100132900、LOC727983、DGCR6、PRODH、DGCR5、LOC100996369、LOC100287576、LOC100506454、DGCR9、DGCR10、DGCR2、DGCR11、DGCR14、TSSK2、GSC2、LOC100652736、SLC25A1、CLTCL1、HIRA、MRPL40、C22orf39、UFD1L、CDC45、CLDN5、LOC150185、SEPT5、SEPT5-GP1BB、GP1BB、TBX1、GNB1L、C22orf29、TXNRD2、COMT、MIR4761、ARVCF、C22orf25、MIR185、DGCR8、MIR3618、MIR1306、TRMT2A、RANBP1、ZDHHC8、LOC388849、LOC284865、LOC150197、RTN4R、MIR1286、DGCR6L、LOC729444、LOC100996401、TMEM191B、PI4KAP1、RIMBP3、ZNF74、SCARF2、KLHL22、MED15、POM121L4P、TMEM191A、PI4KA、SERPIND1、SNAP29、CRKL、AIFM3、LZTR1、THAP7、THAP7-AS1、TUBA3FP、P2RX6、SLC7A4、MIR649、P2RX6P、LOC400891、BCRP2、LOC284861、GGT2、LOC100132705、POM121L8P、LOC100996335、CA15P3、RIMBP3B、HIC2、LOC100996337、TMEM191C、PI4KAP2、RIMBP3C、UBE2L3、YDJC、CCDC116、SDF2L1、MIR301B、MIR130B、PPIL2、YPEL1、MAPK1、PPM1F、LOC100286925、TOP3B、PRAMEL、VPREB1、LOC96610、ZNF280B、ZNF280A、PRAME、LOC648691、POM121L1P、GGTLC2、MIR650、IGLL5、RTDR1、GNAZ、RAB36、BCR、FBXW4P1、CES5AP1、ZDHHC8P1、LOC388882、IGLL1、C22orf43、GUSBP11、RGL4、ZNF70、VPREB3、C22orf15、CHCHD10、MMP11、SMARCB1、DERL3、SLC2A11、LOC284889、MIF、LOC100652871、GSTT2B、DDTL、DDT、GSTT2、GSTTP1、LOC100996594、LOC391322、GSTT1、GSTTP2、CABIN1、LOC100652894、SUSD2、GGT5、POM121L9P、SPECC1L、ADORA2A、ADORA2A-AS1、UPB1、GUCD1、SNRPD3、GGT1、FAM211B、BCRP3、POM121L10P、PIWIL3、TOP1P2、SGSM1、TMEM211、KIAA1671、LOC100128531、CRYBB3、CRYBB2、IGLL3P、LOC100652901、LRP5L、CRYBB2P1、LOC100507580、LOC100996404、ADRBK2、MYO18B、SEZ6L、ASPHD2、HPS4、SRRD、TFIP11、LOC100507599、TPST2、MIR548J、CRYBB1、CRYBA4、MIAT、LOC100507657、MN1、PITPNB、TTC28-AS1、MIR3199-1、MIR3199-2、TTC28、CHEK2、HSCB、CCDC117、XBP1、ZNRF3、ZNRF3-AS1、C22orf31、KREMEN1、EMID1、RHBDD3、EWSR1、GAS2L1、RASL10A、AP1B1、MIR3653、SNORD125、RFPL1-AS1、RFPL1、NEFH、THOC5、NIPSNAP1、NF2、CABP7、ZMAT5、UQCR10、ASCC2、MTMR3、HORMAD2、LIF、OSM、GATSL3、TBC1D10A、SF3A1、CCDC157、KIAA1656、RNF215、SEC14L2、MTFP1、LOC646513、SEC14L3、SDC4P、SEC14L4、SEC14L6、GAL3ST1、PES1、TCN2、SLC35E4、LOC100506075、DUSP18、OSBP2、MIR3200、MORC2-AS1、MORC2、TUG1、SMTN、SELM、INPP5J、PLA2G3、MIR3928、RNF185、LIMK2、PIK3IP1、PATZ1、MGC15705、FLJ20464、DRG1、EIF4ENIF1、RNU6-28、SFI1、PISD、PRR14L、DEPDC5、C22orf24、YWHAH、SLC5A1、AP1B1P1、C22orf42、RFPL2、SLC5A4、RFPL3、RFPL3-AS1、LOC339666、C22orf28、BPIFC、FBXO7、SYN3、TIMP3、LARGE、MIR4764、LOC100506195、ISX、HMGXB4、TOM1、MIR3909、HMOX1、MCM5、RASD2、MB、APOL6、APOL5、RBFOX2、LOC100131802、APOL3、APOL4、APOL2、APOL1、MYH9、TXN2、FOXRED2、EIF3D、CACNG2、IFT27、PVALB、NCF4、CSF2RB、LOC100506241、TEX33、TST、MPST、KCTD17、TMPRSS6、IL2RB、C1QTNF6、SSTR3、RAC2、CYTH4、LOC100506271、ELFN2、MFNG、CARD10、CDC42EP1、LGALS2、GGA1、SH3BP1、PDXP、LGALS1、NOL12、TRIOBP、H1F0、GCAT、GALR3、ANKRD54、MIR658、MIR659、EIF3L、MICALL1、C22orf23、POLR2F、SOX10、MIR4534、PICK1、SLC16A8、BAIAP2L2、PLA2G6、MAFF、TMEM184B、CSNK1E、LOC100996460、LOC400927、KCNJ4、KDELR3、DDX17、DMC1、FAM227A、CBY1、TOMM22、JOSD1、GTPBP1、SUN2、DNAL4、NPTXR、CBX6、APOBEC3A、APOBEC3B、APOBEC3C、APOBEC3D、APOBEC3F、APOBEC3G、APOBEC3H、CBX7、PDGFB、RPL3、SNORD83B、SNORD83A、RNU86、SNORD43、SYNGR1、TAB1、LOC100506472、MGAT3、SMCR7L、ATF4、RPS19BP1、CACNA1I、ENTHD1、GRAP2、FAM83F、LOC100130899、TNRC6B、ADSL、SGSM3、MKL1、MCHR1、SLC25A17、MIR4766、ST13、XPNPEP3、DNAJB7、RBX1、MIR1281、EP300、L3MBTL2、LOC100506544、CHADL、RANGAP1、ZC3H7B、TEF、LOC100996598、TOB2、PHF5A、ACO2、POLR3H、CSDC2、PMM1、DESI1、XRCC6、NHP2L1、LOC100506562、C22orf46、MEI1、CCDC134、SREBF2、MIR33A、SHISA8、MIR378I、TNFRSF13C、CENPM、LINC00634、SEPT3、WBP2NL、NAGA、FAM109B、C22orf32、NDUFA6、LOC100132273、CYP2D6、CYP2D7P1、TCF20、LOC388906、LOC100134361、NFAM1、SERHL、RRP7A、SERHL2、RRP7B、POLDIP3、RNU12、CYB5R3、ATP5L2、A4GALT、ARFGAP3、PACSIN2、LOC100506679、TTLL1、BIK、MCAT、TSPO、TTLL12、SCUBE1、MPPED1、EFCAB6-AS1、EFCAB6、SULT4A1、PNPLA5、PNPLA3、SAMM50、PARVB、PARVG、KIAA1644、LDOC1L、LINC00207、LINC00229、PRR5、PRR5-ARHGAP8、ARHGAP8、PHF21B、LOC100506695、LOC100506714、NUP50、
KIAA0930、MIR1249、UPK3A、FAM118A、SMC1B、RIBC2、FBLN1、LOC100506737、ATXN10、MIR4762、WNT7B、LOC730668、LOC100271722、C22orf26、LOC150381、MIRLET7BHG、MIR3619、MIRLET7A3、MIR4763、MIRLET7B、PPARA、CDPF1、PKDREJ、TTC38、CN5H6.4、GTSE1、TRMU、CELSR1、GRAMD4、CERK、TBC1D22A、LOC100128818、FLJ46257、MIR3201、LOC100506877、FAM19A5、LOC284933、MIR4535、LOC100128946、MIR3667、C22orf34、BRD1、LOC90834、ZBED4、ALG12、CRELD2、PIM3、IL17REL、TTLL8、MLC1、MOV10L1、PANX2、TRABD、SELO、TUBGCP6、HDAC10、MAPK12、MAPK11、PLXNB2、DENND6B、PPP6R2、SBF1、ADM2、MIOX、LMF2、NCAPH2、SCO2、TYMP、ODF3B、KLHDC7B、SYCE3、CPT1B、CHKB-CPT1B、CHKB、LOC100144603、MAPK8IP2、ARSA、SHANK3、ACR、RPL23AP82、RABL2B、CHL1-AS2、CHL1、CNTN6、CNTN4、CNTN4-AS2、IL5RA、TRNT1、CRBN、LRRN1、SETMAR、SUMF1、ITPR1-AS1、ITPR1、EGOT、BHLHE40-AS1、BHLHE40、ARL8B、EDEM1、MIR4790、GRM7、LOC100996542、LMCD1-AS1、LMCD1、LINC00312、SSUH2、CAV3、OXTR、RAD18、SRGAP3、THUMPD3、SETD5-AS1、LOC100996546、SETD5、LHFPL4、MTMR14、CPNE9、BRPF1、OGG1、CAMK1、TADA3、ARPC4、ARPC4-TTLL3、TTLL3、RPUSD3、CIDEC、JAGN1、IL17RE、IL17RC、CRELD1、PRRT3、PRRT3-AS1、EMC3、LOC442075、LOC401052、CIDECP、FANCD2、FANCD2OS、BRK1、VHL、IRAK2、TATDN2、GHRLOS2、GHRL、GHRLOS、SEC13、ATP2B2、MIR378B、MIR885、LINC00606、SLC6A11、SLC6A1、SLC6A1-AS1、HRH1、ATG7、VGLL4、TAMM41、SYN2、TIMP4、PPARG、TSEN2、LOC100129480、MKRN2、RAF1、TMEM40、CAND2、RPL32、SNORA7A、IQSEC1、LOC100128644、NUP210、HDAC11、FBLN2、LOC100293612、LINC00620、WNT7A、FGD5P1、TPRXL、CHCHD4、TMEM43、XPC、LSM3、SLC6A6、GRIP2、CCDC174、C3orf20、FGD5、FGD5-AS1、NR2C2、MRPS25、ZFYVE20、COL6A4P1、CAPN7、SH3BP5-AS1、SH3BP5、METTL6、EAF1、COLQ、MIR4270、HACL1、BTD、ANKRD28、MIR3134、MIR563、GALNTL2、DPH3、OXNAD1、RFTN1、LINC00690、DAZL、PLCL2、MIR3714、TBC1D5、LOC100505786、LOC339862、SATB1、KCNH8、MIR4791、EFHB、RAB5A、PP2D1、KAT2B、MIR3135A、SGOL1、SGOL1-AS1、VENTXP7、ZNF385D、LOC100505836、UBE2E2-AS1、UBE2E2、UBE2E1、NKIRAS1、RPL15、NR1D2、LINC00691、THRB、THRB-AS1、MIR4792、LOC100505947、RARB、TOP2B、MIR4442、NGLY1、OXSM、LINC00692、LRRC3B、NEK10、SLC4A7、EOMES、LOC100996624、CMC1、AZI2、ZCWPW2、LINC00693、LOC100652807、RBMS3、TGFBR2、GADL1、STT3B、OSBPL10、OSBPL10-AS1、ZNF860、GPD1L、CMTM8、CMTM7、CMTM6、DYNC1LI1、CNOT10、YPLR6490、TRIM71、CCR4、GLB1、TMPPE、CRTAP、SUSD5、FBXL2、UBP1、CLASP2、PDCD6IP、ARPP21、MIR128-2、STAC、DCLK3、TRANK1、EPM2AIP1、MLH1、LRRFIP2、GOLGA4、C3orf35、ITGA9、CTDSPL、MIR26A1、
VILL、PLCD1、DLEC1、ACAA1、MYD88、OXSR1、SLC22A13、SLC22A14、XYLB、ACVR2B-AS1、ACVR2B、EXOG、SCN5A、SCN10A、SCN11A、WDR48、GORASP1、TTC21A、CSRNP1、XIRP1、LOC729454、CX3CR1、CCR8、SLC25A38、RPSA、SNORA6、SNORA62、MOBP、MYRIP、EIF1B-AS1、EIF1B、ENTPD3、ENTPD3-AS1、RPL14、ZNF619、ZNF620、ZNF621、CTNNB1、ULK4、TRAK1、CCK、LYZL4、VIPR1、SEC22C、SS18L2、NKTR、ZBTB47、KBTBD5、HHATL、CCDC13、CCDC13-AS1、HIGD1A、CCBP2、CYP8B1、ZNF662、KRBOX1-AS1、KRBOX1、FAM198A、GTDC2、SNRK、SNRK-AS1、ANO10、ABHD5、MIR138-1、TOPAZ1、TCAIM、LOC100506301、LOC100506319、ZNF445、ZNF852、ZNF167、ZNF660、ZNF197、ZNF35、ZNF502、ZNF501、KIAA1143、KIF15、MIR564、TMEM42、TGM4、ZDHHC3、EXOSC7、CLEC3B、CDCP1、TMEM158、LARS2、LARS2-AS1、LIMD1、LIMD1-AS1、SACM1L、SLC6A20、LZTFL1、CCR9、FYCO1、CXCR6、XCR1、CCR1、CCR3、CCR2、CCR5、CCRL2、LTF、RTP3、LRRC2、TDGF1、LOC100132146、ALS2CL、TMIE、PRSS50、PRSS46、PRSS45、PRSS42、MYL3、LOC100996656、PTH1R、CCDC12、NBEAL2、NRADDP、SETD2、FLJ39534、KIF9、KLHL18、PTPN23、SCAP、ELP6、CSPG5、SMARCC1、LOC100996661、DHX30、MIR1226、MAP4、CDC25A、MIR4443、CAMP、ZNF589、NME6、SPINK8、MIR2115、FBXW12、PLXNB1、CCDC51、TMA7、ATRIP、TREX1、SHISA5、PFKFB4、UCN2、COL7A1、MIR711、UQCRC1、TMEM89、SLC26A6、CELSR3、MIR4793、NCKIPSD、IP6K2、PRKAR2A、PRKAR2A-AS1、SLC25A20、ARIH2OS、ARIH2、LOC100506651、P4HTM、WDR6、DALRD3、MIR425、NDUFAF3、MIR191、IMPDH2、QRICH1、QARS、USP19、LAMB2、LAMB2P1、CCDC71、KLHDC8B、LOC646498、CCDC36、STGC3、C3orf62、MIR4271、USP4、GPX1、RHOA、TCTA、AMT、NICN1、DAG1、BSN-AS2、BSN、APEH、MST1、RNF123、AMIGO3、GMPPB、IP6K1、CDHR4、FAM212A、UBA7、MIR5193、TRAIP、CAMKV、MST1R、MON1A、RBM6、RBM5、LUST、LOC100129060、SEMA3F、MIR566、GNAT1、SLC38A3、GNAI2、SEMA3B、C3orf45、IFRD2、HYAL3、NAT6、HYAL1、HYAL2、TUSC2、RASSF1、ZMYND10、NPRL2、CYB561D2、TMEM115、CACNA2D2、C3orf18、HEMK1、CISH、MAPKAPK3、MIR4787、DOCK3、MANF、RBM15B、VPRBP、RAD54L2、TEX264、GRM2、IQCF6、IQCF4、IQCF3、IQCF2、IQCF5、IQCF1、RRP9、PARP3、GPR62、PCBP4、ABHD14B、ABHD14A-ACY1、ABHD14A、ACY1、RPL29、DUSP7、C3orf74、POC1A、ALAS1、TLR9、TWF2、PPM1M、WDR82、MIRLET7G、GLYCTK、MIR135A1、DNAH1、BAP1、PHF7、SEMA3G、TNNC1、NISCH、STAB1、NT5DC2、SMIM4、PBRM1、GNL3、SNORD19、SNORD19B、SNORD69、GLT8D1、SPCS1、NEK4、ITIH1、ITIH3、ITIH4、TMEM110-MUSTN1、MUSTN1、TMEM110、SFMBT1、RFT1、PRKCD、TKT、DCP1A、CACNA1D、CHDH、IL17RB、ACTR8、SELK、CACNA2D3、ESRG、CACNA2D3-AS1、LRTM1、WNT5A、ERC2、ERC2-IT1、MIR3938、CCDC66、FAM208A、ARHGEF3、
ARHGEF3-AS1、SPATA12、IL17RD、HESX1、APPL1、ASB14、DNAH12、PDE12、ARF4、DENND6A、SLMAP、FLNB、DNASE1L3、ABHD6、RPP14、PXK、PDHB、KCTD6、ACOX2、FAM107A、FAM3D、C3orf67、FHIT、NPCDR1、PTPRG、LOC100506994、C3orf14、FEZF2、CADPS、LOC285401、SYNPR、SYNPR-AS1、SNTN、C3orf49、THOC7、ATXN7、PSMD6-AS2、PSMD6、PRICKLE2-AS1、LOC100287879、PRICKLE2、PRICKLE2-AS2、PRICKLE2-AS3、ADAMTS9、ADAMTS9-AS2、MAGI1、MAGI1-IT1、MAGI1-AS1、LOC100508226、SLC25A26、LRIG1、LOC100996321、KBTBD8、MIR4272、SUCLG2、FAM19A1、FAM19A4、EOGT、TMF1、MIR3136、UBA3、ARL6IP5、LMOD3、FRMD4B、MITF、FOXP1、MIR1284、FOXP1-IT1、EIF4E3、GPR27、PROK2、LOC201617、RYBP、LOC100506865、SHQ1、GXYLT2、PPP4R2、EBLN2、PDZRN3、CNTN3、FAM86DP、MIR1324、FRG2C、LOC100996350、LOC401074、ZNF717、MIR4273、ROBO2、ROBO1、MIR3923、LOC728290、GBE1、LOC440970、CADM2、MIR5688、CADM2-AS2、VGLL3、MIR4795、CHMP2B、POU1F1、HTR1F、CGGBP1、ZNF654、C3orf38、LOC100506944、EPHA3、PROS1、ARL13B、STX19、DHFRL1、NSUN3、LOC255025、EPHA6、ARL6、CRYBG3、MINA、GABRR3、OR5AC2、OR5H1、OR5H14、OR5H15、OR5H6、OR5H2、OR5K4、OR5K3、OR5K1、OR5K2、CLDND1、GPR15、CPOX、ST3GAL6-AS1、ST3GAL6、DCBLD2、RNU6-8、LOC100506377、COL8A1、CMSS1、FILIP1L、MIR3921、TMEM30C、TBC1D23、NIT2、TOMM70A、LNP1、TMEM45A、GPR128、TFG、ABI3BP、IMPG2、SENP7、LOC100287852、FAM172BP、TRMT10C、PCNP、ZBTB11、LOC100009676、RPL24、PDCL3P4、CEP97、NXPE3、NFKBIZ、LOC152225、ZPLD1、MIR548AB、ALCAM、CBLB、LOC100302640、LOC344595、CCDC54、BBX、LINC00635、LINC00636、CD47、IFT57、HHLA2、MYH15、KIAA1524、DZIP3、RETNLB、TRAT1、GUCA1C、MORC1、FLJ22763、LINC00488、DPPA2、DPPA4、FLJ25363、MIR4445、LOC151760、PVRL3-AS1、PVRL3、CD96、ZBED2、PLCXD2、PHLDB2、ABHD10、TAGLN3、TMPRSS7、C3orf52、MIR567、GCSAM、SLC9C1、CD200、BTLA、ATG3、SLC35A5、CCDC80、CD200R1L、CD200R1、GTPBP8、C3orf17、BOC、WDR52、WDR52-AS1、SPICE1、SIDT1、MIR4446、KIAA2018、NAA50、ATP6V1A、GRAMD1C、ZDHHC23、KIAA1407、QTRTD1、DRD3、ZNF80、TIGIT、MIR568、ZBTB20、ZBTB20-AS1、MIR4796、GAP43、LSAMP、LSAMP-AS3、MIR4447、LSAMP-AS4、IGSF11、IGSF11-AS1、C3orf30、UPK1B、B4GALT4、ARHGAP31、TMEM39A、POGLUT1、TIMMDC1、CD80、ADPRH、PLA1A、POPDC2、COX17、MAATS1、NR1I2、GSK3B、LOC100996310、GPR156、LRRC58、FSTL1、MIR198、NDUFB4、HGD、RABL3、GTF2E1、STXBP5L、MIR5682、POLQ、ARGFX、FBXO40、HCLS1、GOLGB1、IQCB1、EAF2、SLC15A2、ILDR1、CD86、CASR、CSTA、CCDC58、FAM162A、WDR5B、KPNA1、PARP9、DTX3L、PARP15、PARP14、HSPBAP1、DIRC2、LOC100129550、SEMA5B、PDIA5、
SEC22A、ADCY5、PTPLB、MYLK-AS1、MYLK、CCDC14、ROPN1、KALRN、MIR5002、UMPS、MIR544B、ITGB5、MUC13、HEG1、SLC12A8、MIR5092、ZNF148、SNX4、OSBPL11、MIR548I1、FAM86JP、ALG1L、ROPN1B、SLC41A3、ALDH1L1、ALDH1L1-AS1、ALDH1L1-AS2、KLF15、LOC100506907、CCDC37、ZXDC、UROC1、CHST13、C3orf22、TXNRD3NB、TXNRD3、NUP210P1、CHCHD6、LOC100132481、PLXNA1、C3orf56、TPRA1、MCM2、PODXL2、ABTB1、MGLL、KBTBD12、SEC61A1、RUVBL1、EEFSEC、DNAJB8、DNAJB8-AS1、GATA2、LOC90246、C3orf27、RPN1、RAB7A、LOC653712、ACAD9、KIAA1257、CCDC48、GP9、RAB43、ISY1-RAB43、ISY1、CNBP、COPG1、C3orf37、H1FX、H1FX-AS1、RPL32P3、SNORA7B、EFCAB12、MBD4、IFT122、RHO、H1FOO、PLXND1、TMCC1、LOC100507032、TRH、ARVP6125、ALG1L2、FAM86HP、COL6A4P2、COL6A5、COL6A6、PIK3R4、ATP2C1、ASTE1、NEK11、LOC339874、NUDT16P1、NUDT16、MRPL3、SNORA58、LOC100507134、CPNE4、MIR5704、ACPP、LOC100996371、DNAJC13、NPHP3-ACAD11、ACAD11、CCRL1、UBA5、NPHP3、NPHP3-AS1、TMEM108、BFSP2、CDV3、TOPBP1、TF、SRPRB、RAB6B、C3orf36、SLCO2A1、LOC100507210、RYK、AMOTL2、LOC100507224、MIR4788、ANAPC13、CEP63、KY、EPHB1、PPP2R3A、MSL2、PCCB、STAG1、SLC35G2、NCK1、IL20RB、SOX14、LOC100507274、CLDN18、DZIP1L、A4GNT、DBR1、ARMC8、NME9、MRAS、ESYT3、CEP70、FAIM、PIK3CB、FOXL2、C3orf72、PRR23A、PRR23B、PRR23C、BPESC1、PISRT1、MRPS22、COPB2、LOC100507291、RBP2、RBP1、NMNAT3、CLSTN2、TRIM42、SLC25A36、SPSB4、ACPL2、ZBTB38、RASA2、LOC646730、RNF7、GRK7、ATP1B3、TFDP2、GK5、XRN1、ATR、PLS1、TRPC1、PCOLCE2、LOC100507389、PAQR9、LOC100289361、U2SURP、CHST2、SLC9A9、SLC9A9-AS1、C3orf58、PLOD2、PLSCR4、LOC440981、PLSCR2、PLSCR1、PLSCR5、ZIC4、ZIC1、LOC100507447、LOC100507461、AGTR1、CPB1、CPA3、GYG1、HLTF、HLTF-AS1、HPS3、CP、TM4SF18、TM4SF1、TM4SF4、WWTR1、WWTR1-AS1、COMMD2、ANKUB1、RNF13、PFN2、LOC646903、TMEM183B、TSC22D2、SERP1、EIF2A、SELT、FAM194A、SIAH2、CLRN1、CLRN1-AS1、MED12L、GPR171、P2RY14、GPR87、P2RY13、P2RY12、IGSF10、MIR5186、AADACL2、LOC201651、AADAC、SUCNR1、LOC401093、MBNL1、TMEM14E、P2RY1、RAP2B、C3orf79、ARHGEF26-AS1、ARHGEF26、DHX36、GPR149、MME、LOC100507537、PLCH1、LOC100507556、C3orf33、SLC33A1、GMPS、KCNAB1、KCNAB1-AS2、KCNAB1-AS1、SSR3、TIPARP-AS1、TIPARP、LOC730091、PA2G4P4、LEKR1、LOC339894、LOC100498859、CCNL1、VEPH1、PTX3、C3orf55、SHOX2、RSRC1、LOC100996447、MLF1、GFM1、LXN、RARRES1、LOC100287290、MFSD1、IQCJ-SCHIP1、IQCJ、SCHIP1、MIR3919、IL12A、C3orf80、IFT80、SMC4、MIR15B、MIR16-2、TRIM59、KPNA4、SCARNA7、ARL14、PPM1L、B3GALNT1、NMD3、SPTSSB、OTOL1、LOC647107、
MIR1263、SI、SLITRK3、BCHE、ZBBX、SERPINI2、WDR49、PDCD10、SERPINI1、LOC100996456、LOC646168、GOLIM4、EGFEM1P、MIR551B、LOC100507661、MECOM、TERC、ACTRT3、MYNN、LRRC34、LRRIQ4、LRRC31、SAMD7、LOC100128164、SEC62、GPR160、PHC3、PRKCI、SKIL、CLDN11、SLC7A14、RPL22L1、EIF5A2、SLC2A2、TNIK、MIR569、PLD1、TMEM212、FNDC3B、GHSR、TNFSF10、NCEH1、ECT2、SPATA16、NLGN1、NAALADL2、NAALADL2-AS3、MIR4789、LOC100505547、TBL1XR1、LINC00578、KCNMB2-IT1、KCNMB2、ZMAT3、PIK3CA、KCNMB3、ZNF639、MFN1、GNB4、ACTL6A、MRPL47、NDUFB5、USP13、PEX5L、LOC100505609、TTC14、CCDC39、FXR1、DNAJC19、SOX2-OT、SOX2、LOC100996490、FLJ46066、ATP11B、DCUN1D1、MCCC1、LAMP3、MCF2L2、B3GNT5、LOC100505687、KLHL6、KLHL24、YEATS2、MAP6D1、PARL、MIR4448、ABCC5、ABCC5-AS1、HTR3D、HTR3C、HTR3E、EIF2B5、DVL3、AP2M1、ABCF3、VWA5B2、MIR1224、ALG3、ECE2、CAMK2N2、PSMD2、EIF4G1、SNORD66、FAM131A、CLCN2、POLR2H、THPO、CHRD、EPHB3、MAGEF1、LOC100505710、VPS8、LOC100505729、C3orf70、EHHADH-AS1、EHHADH、MAP3K13、TMEM41A、LIPH、SENP2、IGF2BP2、C3orf65、MIR548AQ、TRA2B、LOC344887、ETV5、DGKG、LOC253573、CRYGS、TBCCD1、DNAJB11、AHSG、FETUB、HRG、KNG1、EIF4A2、SNORD2、SNORA81、SNORA63、SNORA4、RFC4、ADIPOQ、ADIPOQ-AS1、ST6GAL1、LOC100508227、RPL39L、RTP1、MASP1、RTP4、SST、RTP2、LOC100131635、BCL6、LPP-AS2、LPP、FLJ42393、MIR28、TPRG1、TPRG1-AS2、TP63、MIR944、LEPREL1、CLDN1、CLDN16、TMEM207、IL1RAP、GMNC、SNAR-I、OSTN、UTS2D、CCDC50、PYDC2、FGF12、MB21D2、HRASLS、MGC2889、ATP13A5、ATP13A4、OPA1、OPA1-AS1、LOC647323、LOC100128023、LOC100505902、HES1、LOC100505920、LOC100131551、CPN2、LRRC15、GP5、ATP13A3、FLJ34208、LOC100507033、TMEM44-AS1、TMEM44、LSG1、FAM43A、LOC100507391、XXYLT1、MIR3137、ACAP2、PPP1R2、APOD、SDHAP2、MIR570、LOC440993、MUC20、MUC4、TNK2、LOC100128262、SDHAP1、TFRC、LOC401109、ZDHHC19、SLC51A、PCYT1A、TCTEX1D2、TM4SF19-TCTEX1D2、TM4SF19、UBXN7、RNF168、C3orf43、WDR53、FBXO45、LRRC33、CEP19、PIGX、PAK2、RNU6-42、SENP5、NCBP2、LOC152217、PIGZ、MFI2、MFI2-AS1、DLG1、MIR4797、DLG1-AS1、LOC100129516、BDH1、LOC220729、KIAA0226、MIR922、FYTTD1、LRCH3、IQCG、RPL35A、LMLN、ANKRD18DP、FAM157A、ZNF595、ZNF718、ZNF876P、ZNF732、LOC100996363、ZNF141、MIR571、ABCA11P、ZNF721、PIGG、PDE6B、ATP5I、MYL5、MFSD7、PCGF3、LOC100129917、CPLX1、GAK、TMEM175、DGKQ、SLC26A1、IDUA、FGFRL1、RNF212、TMED11P、FLJ35816、SPON2、LOC100130872、LOC285463、CTBP1、CTBP1-AS1、MAEA、UVSSA、CRIPAK、LOC100507054、FAM53A、SLBP、TMEM129、TACC3、FGFR3、LETM1、WHSC1、SCARNA22、WHSC2、
MIR943、C4orf48、NAT8L、POLN、HAUS3、MXD4、MIR4800、ZFYVE28、LOC402160、RNF4、FAM193A、TNIP2、SH3BP2、ADD1、MFSD10、NOP14-AS1、NOP14、GRK4、HTT-AS1、HTT、MSANTD1、RGS12、HGFAC、DOK7、LRPAP1、FLJ35424、LOC100133461、LOC100507150、ADRA2C、FAM86EP、OTOP1、TMEM128、LYAR、ZBTB49、NSG1、STX18、LOC100507266、MSX1、CYTL1、STK32B、C4orf6、EVC2、EVC、CRMP1、MIR378D1、C4orf50、JAKMIP1、LOC285484、WFS1、PPP2R2C、MAN2B2、MRFAP1、LOC100507376、LOC93622、S100P、MRFAP1L1、BLOC1S4、KIAA0232、TBC1D14、LOC100129931、CCDC96、TADA2B、GRPEL1、FLJ36777、SORCS2、MIR4798、PSAPL1、MIR4274、AFAP1-AS1、AFAP1、ABLIM2、MIR95、SH3TC1、HTRA3、ACOX3、TRMT44、GPR78、CPZ、HMX1、LOC650293、USP17L10、USP17L11、USP17L12、USP17L13、USP17L15、USP17L17、USP17L18、USP17L19、USP17L20、USP17L21、USP17L22、USP17L24、USP17L25、USP17L26、USP17L5、USP17L27、USP17L28、USP17L29、USP17L9P、USP17L30、USP17L6P、DEFB131、MIR548I2、DRD5、SLC2A9、WDR1、MIR3138、ZNF518B、CLNK、MIR572、HS3ST1、HSP90AB2P、RAB28、LOC285547、NKX3-2、LOC285548、BOD1L1、MIR5091、LOC152742、LOC441009、CPEB2、C1QTNF7、CC2D2A、FBXL5、LOC100996623、FAM200B、BST1、CD38、FGFBP1、FGFBP2、PROM1、TAPT1、TAPT1-AS1、LDB2、QDPR、CLRN2、LAP3、MED28、FAM184B、DCAF16、NCAPG、LCORL、SLIT2、SLIT2-IT1、MIR218-1、PACRGL、KCNIP4、KCNIP4-IT1、LOC100505912、GPR125、GBA3、PPARGC1A、LOC729175、MIR573、DHX15、SOD3、CCDC149、LGI2、SEPSECS、LOC285540、PI4K2B、ZCCHC4、ANAPC4、SLC34A2、LOC100996632、SEL1L3、C4orf52、RBPJ、CCKAR、TBC1D19、LOC100506048、STIM2、MIR4275、PCDH7、ARAP2、DTHD1、MIR1255B1、MIR4801、KIAA1239、C4orf19、RELL1、PGM2、TBC1D1、PTTG2、FLJ13197、KLF3、TLR10、TLR1、TLR6、FAM114A1、MIR574、TMEM156、KLHL5、WDR19、RFC1、KLB、MIR5591、RPL9、LIAS、LOC401127、UGDH、UGDH-AS1、C4orf34、UBE2K、PDS5A、LOC344967、N4BP2、RHOH、CHRNA9、RBM47、MIR4802、NSUN7、APBB2、UCHL1、LIMCH1、PHOX2B、TMEM33、DCAF4L1、SLC30A9、BEND4、SHISA3、ATP8A1、GRXCR1、LOC100506827、KCTD8、YIPF7、GUF1、GNPDA2、GABRG1、GABRA2、COX7B2、GABRA4、GABRB1、COMMD8、ATP10D、CORIN、NFXL1、CNGA1、NIPAL1、TXK、TEC、SLAIN2、SLC10A4、ZAR1、FRYL、OCIAD1、OCIAD2、CWH43、DCUN1D4、LRRC66、SGCB、SPATA18、USP46、USP46-AS1、DANCR、MIR4449、SNORA26、ERVMER34-1、LOC152578、RASL11B、SCFD2、FIP1L1、LNX1、LNX1-AS1、LNX1-AS2、RPL21P44、CHIC2、GSX2、PDGFRA、KIT、KDR、SRD5A3、SRD5A3-AS1、TMEM165、CLOCK、PDCL2、NMU、LOC644145、EXOC1、CEP135、KIAA1211、AASDH、PPAT、PAICS、SRP72、ARL9、THEGL、HOPX、SPINK2、REST、NOA1、POLR2B、IGFBP7、LOC255130、LOC100507160、
MIR548AG1、LPHN3、TECRL、LOC401134、EPHA5、LOC100144602、MIR1269A、CENPC1、STAP1、UBA6、LOC550112、GNRHR、TMPRSS11D、TMPRSS11A、TMPRSS11GP、TMPRSS11F、LOC550113、SYT14L、FTLP10、TMPRSS11BNL、TMPRSS11B、YTHDC1、TMPRSS11E、UGT2B17、UGT2B15、UGT2B10、UGT2A3、UGT2B7、UGT2B11、UGT2B28、UGT2B4、UGT2A1、UGT2A2、SULT1B1、SULT1E1、CSN1S1、CSN2、STATH、HTN3、HTN1、CSN1S2AP、CSN1S2BP、C4orf40、ODAM、FDCSP、CSN3、CABS1、SMR3A、SMR3B、PROL1、MUC7、AMTN、AMBN、ENAM、IGJ、UTP3、RUFY3、GRSF1、MOB1B、DCK、SLC4A4、GC、NPFFR2、ADAMTS3、COX18、ANKRD17、ALB、AFP、AFM、LOC728040、RASSF6、IL8、CXCL6、PF4V1、CXCL1、PF4、PPBP、CXCL5、CXCL3、PPBPP2、CXCL2、MTHFD2L、EPGN、EREG、AREG、AREGB、BTC、PARM1、LOC100507388、LOC100505946、LOC100506253、LOC441025、RCHY1、THAP6、C4orf26、CDKL2、G3BP2、USO1、PPEF2、NAAA、SDAD1、CXCL9、ART3、CXCL10、CXCL11、NUP54、SCARB2、FAM47E、FAM47E-STBD1、STBD1、CCDC158、SHROOM3、MIR4450、MIR548AH、LOC100996628、SOWAHB、SEPT11、LOC100131826、CCNI、CCNG2、CXCL13、CNOT6L、MRPL1、FRAS1、ANXA3、LOC100505702、BMP2K、MIR5096、PAQR3、LOC100505875、NAA11、GK2、LOC100506035、GDEP、ANTXR2、PRDM8、FGF5、C4orf22、BMP3、PRKG2、RASGEF1B、HNRNPD、HNRPDL、ENOPH1、TMEM150C、LINC00575、SCD5、MIR575、SEC31A、THAP9-AS1、THAP9、LIN54、COPS4、PLAC8、COQ2、HPSE、HELQ、MRPS18C、FAM175A、AGPAT9、NKX6-1、CDS1、WDFY3、WDFY3-AS2、ARHGAP24、MIR4451、MAPK10、MIR4452、PTPN13、SLC10A6、C4orf36、LOC100506746、AFF1、KLHL8、MIR5705、HSD17B13、HSD17B11、NUDT9、SPARCL1、DSPP、DMP1、IBSP、MEPE、HSP90AB3P、SPP1、PKD2、ABCG2、PPM1K、HERC6、HERC5、PYURF、PIGY、HERC3、RNU6-33、NAP1L5、FAM13A-AS1、FAM13A、TIGD2、GPRIN3、SNCA、LOC644248、MMRN1、FAM190A、GRID2、ATOH1、SMARCAD1、HPGDS、PDLIM5、LOC100507012、BMPR1B、UNC5C、PDHA2、RNU6-34、STPG2、RAP1GDS1、TSPAN5、EIF4E、METAP1、MIR3684、ADH5、LOC100507053、ADH4、PCNAP1、ADH6、ADH1A、ADH1B、ADH1C、ADH7、C4orf17、TRMT10A、MTTP、LOC285556、DAPP1、LAMTOR3、DNAJB14、H2AFZ、LOC256880、DDIT4L、EMCN、EMCN-IT3、PPP3CA、MIR1255A、FLJ20021、BANK1、SLC39A8、NFKB1、MANBA、UBE2D3、CISD2、SLC9B1、SLC9B2、BDH2、CENPE、TACR3、CXXC4、TET2、PPA2、ARHGEF38、ARHGEF38-IT1、INTS12、GSTCD、NPNT、TBCK、AIMP1、GIMD1、DKK2、PAPSS1、SGMS2、CYP2U1、HADH、LEF1、LEF1-AS1、RPL34-AS1、RPL34、OSTC、AGXT2L1、COL25A1、SEC24B-AS1、SEC24B、MIR576、CCDC109B、CASP6、PLA2G12A、CFI、GAR1、RRH、LRIT3、EGF、RNU6-35、ELOVL6、ENPEP、PITX2、MIR297、C4orf32、AP1AR、TIFA、ALPK1、NEUROG2、C4orf21、LARP7、MIR367、MIR302D、MIR302A、
MIR302C、MIR302B、ANK2、MIR1243、CAMK2D、LOC100507209、ARSJ、UGT8、MIR577、NDST4、MIR1973、TRAM1L1、NDST3、SNHG8、SNORA24、PRSS12、CEP170P1、METTL14、SEC24D、SYNPO2、MYOZ2、USP53、C4orf3、FABP2、FLJ14186、LOC100507306、LOC645513、PDE5A、LOC100996694、MAD2L1、PRDM5、NDNF、TNIP3、QRFPR、ANXA5、TMEM155、PP12613、EXOSC9、CCNA2、BBS7、TRPC3、KIAA1109、ADAD1、IL2、IL21、CETN4P、BBS12、FGF2、NUDT6、SPATA5、SPRY1、LOC285419、ANKRD50、FAT4、MIR2054、INTU、SLC25A31、HSPA4L、PLK4、MFSD8、C4orf29、LARP1B、PGRMC2、LOC100507487、PHF17、SCLT1、C4orf33、PCDH10、PABPC4L、LINC00613、PCDH18、LINC00616、SLC7A11-AS1、SLC7A11、LINC00499、CCRN4L、ELF2、MGARP、NDUFC1、NAA15、RAB33B、SETD7、MGST2、MAML3、SCOC、LOC100129858、CLGN、ELMOD2、UCP1、TBC1D9、RNF150、ZNF330、LOC100507639、IL15、INPP4B、USP38、GAB1、MIR3139、SMARCA5、SMARCA5-AS1、GUSBP5、FREM3、GYPE、GYPB、GYPA、HHIP-AS1、HHIP、LOC100505491、ANAPC10、ABCE1、OTUD4、SMAD1、MMAA、C4orf51、ZNF827、LOC100505545、LSM6、LOC345051、SLC10A7、POU4F2、TTC29、LOC100505596、MIR548G、EDNRA、TMEM184C、PRMT10、ARHGAP10、MIR4799、NR3C2、LOC285423、DCLK2、LRBA、MAB21L2、RPS3A、SNORD73A、SH3D19、PRSS48、FAM160A1、PET112、LOC100505685、LOC100996286、FBXW7、MIR3140、DKFZP434I0714、MIR4453、TMEM154、TIGD4、ARFIP1、FHDC1、TRIM2、ANXA2P1、MND1、KIAA0922、TLR2、RNF175、SFRP2、DCHS2、PLRG1、FGB、FGA、FGG、LRAT、RBM46、NPY2R、MAP9、GUCY1A3、GUCY1B3、ASIC5、TDO2、CTSO、LOC100505784、PDGFC、GLRB、GRIA2、LOC340017、FAM198B、TMEM144、RXFP1、C4orf46、ETFDH、PPID、FNIP2、C4orf45、MIR3688-1、MIR3688-2、RAPGEF2、FSTL5、MIR4454、NAF1、NPY1R、NPY5R、TKTL2、TMA16、MARCH1、ANP32C、LOC100505989、LOC100506013、TRIM61、FAM218A、TRIM60、TMEM192、KLHL2、GK3P、MSMO1、CPE、MIR578、TLL1、SPOCK3、ANXA10、DDX60、DDX60L、PALLD、CBR4、SH3RF1、NEK1、CLCN3、C4orf27、LOC100506085、MFAP3L、AADAT、HSP90AA6P、LOC100506107、LOC100506122、GALNTL6、GALNT7、MIR548T、HMGB2、SAP30、SCRG1、HAND2、NBLA00301、LOC100506154、FBXO8、CEP44、MIR4276、HPGD、GLRA3、ADAM29、GPM6A、WDR17、SPATA4、ASB5、SPCS3、VEGFC、NEIL3、AGA、LOC285501、LINC00290、MGC45800、MIR1305、TENM3、DCTD、FAM92A1P2、WWC2-AS2、WWC2、CLDN22、CLDN24、CDKN2AIP、LOC389247、ING2、RWDD4、TRAPPC11、STOX2、ENPP6、LOC391722、LOC728175、IRF2、LOC100996305、CASP3、CCDC111、MLF1IP、ACSL1、SLED1、LOC731424、MIR3945、LOC100506229、MIR4455、HELT、SLC25A4、KIAA1430、SNX25、LRP2BP、ANKRD37、UFSP2、C4orf47、CCDC110、PDLIM3、SORBS2、TLR3、FAM149A、FLJ38576、CYP4V2、KLKB1、F11、LOC285441、
MTNR1A、FAT1、LOC339975、LOC100506272、ZFP42、TRIML2、TRIML1、LOC401164、HSP90AA4P、FRG1、DUX4L9、FRG2、DUX2、DUX4L7、DUX4L6、DUX4L5、DUX4L4、DUX4、DUX4L3、DUX4L2、PLEKHG4B、LRRC14B、CCDC127、SDHA、PDCD6、AHRR、C5orf55、EXOC3、PP7080、SLC9A3、LOC100288152、MIR4456、LOC100996325、CEP72、TPPP、LOC100996452、ZDHHC11、BRD9、TRIP13、LOC100506688、NKD2、SLC12A7、LOC100506766、MIR4635、SLC6A19、SLC6A18、TERT、MIR4457、CLPTM1L、LOC100506791、SLC6A3、LPCAT1、SDHAP3、LOC728613、MIR4277、MRPL36、NDUFS6、IRX4、LOC100506858、IRX2、C5orf38、LOC285577、IRX1、LOC340094、ADAMTS16、KIAA0947、FLJ33360、MED10、UBE2QL1、LOC255167、NSUN2、SRD5A1、PAPD7、MIR4278、LOC442132、ADCY2、C5orf49、FASTKD3、MTRR、LOC729506、LOC100505738、MIR4458、SEMA5A、MIR4636、LOC100505806、SNORD123、TAS2R1、LOC285692、FAM173B、CCT5、CMBL、MARCH6、ROPN1L-AS1、ROPN1L、ANKRD33B、DAP、CTNND2、TAG、DNAH5、TRIO、LOC100133299、FAM105A、FAM105B、ANKH、LOC100130744、LOC100128508、MIR4637、FBXL7、MIR887、MARCH11、LOC401176、ZNF622、FAM134B、MYO10、LOC285696、BASP1、LOC401177、CDH18、GUSBP1、LOC100506217、CDH12、PMCHL1、PRDM9、C5orf17、CDH10、LOC340107、CDH9、LOC643401、LSP1P3、CDH6、DROSHA、C5orf22、PDZD2、MIR4279、GOLPH3、MTMR12、ZFR、MIR579、SUB1、NPR3、LOC340113、TARS、ADAMTS12、RXFP3、SLC45A2、AMACR、C1QTNF3-AMACR、C1QTNF3、LOC646652、LOC401180、RAI14、TTC23L、RAD1、BRIX1、DNAJC21、LOC100996421、AGXT2、PRLR、SPEF2、IL7R、CAPSL、LOC100506406、UGT3A1、UGT3A2、LMBRD2、MIR580、SKP2、NADKD1、RANBP3L、SLC1A3、LOC646719、NIPBL、C5orf42、NUP155、WDR70、GDNF、GDNF-AS1、EGFLAM、EGFLAM-AS4、EGFLAM-AS2、LIFR、LIFR-AS1、MIR3650、OSMR、RICTOR、FYB、C9、DAB2、PTGER4、TTC33、PRKAA1、LOC100506548、RPL37、SNORD72、CARD6、C7、HEATR7B2、C6、PLCXD3、OXCT1、C5orf51、FBXO4、GHR、CCDC152、SEPP1、LOC648987、ANXA2R、LOC153684、LOC100132356、ZNF131、NIM1、HMGCS1、CCL28、C5orf28、C5orf34、PAIP1、LOC100652772、NNT、FGF10、LOC100996444、LOC100506674、MRPS30、HCN1、EMB、PARP8、LOC100287592、LOC642366、ISL1、LOC100506329、PELO、ITGA1、ITGA2、MOCS2、LOC257396、FST、NDUFS4、ARL15、MIR581、MIR4459、HSPB3、SNX18、ESM1、GZMK、GZMA、CDC20B、GPX8、MIR449A、MIR449B、MIR449C、MCIN、CCNO、DHX29、SKIV2L2、PPAP2A、MIR5687、RNF138P1、SLC38A9、DDX4、IL31RA、IL6ST、FLJ31104、ANKRD55、LOC100509780、MAP3K1、SETD9、MIER3、GPBP1、ACTBL2、LOC100996645、PLK2、GAPT、MIR548AE2、RAB3C、PDE4D、MIR582、PART1、DEPDC1B、ELOVL7、ERCC8、NDUFAF2、C5orf43、ZSWIM6、C5orf64、LOC100506526、KIF2A、
DIMT1、IPO11、LRRC70、HTR1A、RNF180、RGS7BP、FAM159B、SREK1IP1、CWC27、ADAMTS6、CENPK、PPWD1、TRIM23、C5orf44、SGTB、NLN、ERBB2IP、LOC100303749、SREK1、MAST4、CD180、PIK3R1、SLC30A5、CCNB1、CENPH、MRPS36、CDK7、CCDC125、TAF9、RAD17、MARVELD2、OCLN、GTF2H2C、LOC100272216、LOC100652783、GUSBP3、LOC728093、SERF1B、SMN2、LOC100170939、SMA4、GTF2H2B、SMA5、LOC100652799、SERF1A、SMN1、NAIP、GTF2H2、LOC647859、GUSBP9、PMCHL2、BDP1、MCCC2、CARTPT、MAP1B、MIR4803、MRPS27、PTCD2、ZNF366、TNPO1、MIR4804、FCHO2、TMEM171、TMEM174、FOXD1、BTF3、ANKRA2、UTP15、ARHGEF28、ENC1、HEXB、GFM2、NSA2、FAM169A、LOC100996319、GCNT4、ANKRD31、HMGCR、COL4A3BP、POLK、ANKDD1B、POC5、SV2C、IQGAP2、F2RL2、NCRUPAR、F2R、F2RL1、S100Z、CRHBP、AGGF1、ZBED3、SNORA47、ZBED3-AS1、PDE8B、WDR41、OTP、TBCA、AP3B1、LOC728769、SCAMP1、LHFPL2、ARSB、DMGDH、BHMT2、BHMT、JMY、HOMER1、PAPD4、CMYA5、MTX3、THBS4、SERINC5、LOC644936、SPZ1、CRSP8P、ZFYVE16、FAM151B、ANKRD34B、DHFR、MTRNR2L2、MSH3、RASGRF2、CKMT2、LOC100131067、ZCCHC9、ACOT12、SSBP2、ATG10、RPS23、ATP6AP1L、FLJ41309、MIR3977、TMEM167A、SCARNA18、XRCC4、VCAN、HAPLN1、EDIL3、NBPF22P、COX7C、MIR3607、LOC100505878、MIR4280、RASA1、CCNH、TMEM161B、TMEM161B-AS1、LINC00461、MIR9-2、LOC100505949、MEF2C、MIR3660、CETN3、MBLAC2、POLR3G、LYSMD3、GPR98、LOC729040、LOC100505994、ARRDC3、ARRDC3-AS1、LOC100505822、FLJ42709、NR2F1、FAM172A、MIR2277、POU5F2、KIAA0825、ANKRD32、MCTP1、FAM81B、TTC37、ARSK、GPR150、RFESD、SPATA9、RHOBTB3、GLRX、C5orf27、ELL2、MIR583、PCSK1、CAST、ERAP1、ERAP2、LNPEP、LIX1、RIOK2、RGMB、FLJ35946、CHD1、LOC100289230、LOC100133050、FAM174A、ST8SIA4、MIR548P、SLCO4C1、SLCO6A1、PAM、GIN1、PPIP5K2、C5orf30、NUDT12、RAB9BP1、EFNA5、LOC100129233、FBXL17、HP07349、FER、PJA2、MAN2A1、LOC100289673、TMEM232、MIR548F3、SLC25A46、TSLP、WDR36、CAMK4、STARD4、STARD4-AS1、NREP、NREP-AS1、EPB41L4A-AS1、SNORA13、EPB41L4A、FLJ11235、APC、SRP19、REEP5、DCP2、MCC、TSSK1B、YTHDC2、KCNN2、TRIM36、PGGT1B、CCDC112、FEM1C、TMED7-TICAM2、TICAM2、TMED7、CDO1、ATG12、AP3S1、AQPEP、ARL14EPL、COMMD10、SEMA6A、LOC728342、LOC100505811、DTWD2、MIR1244-2、DMXL1、MIR5706、TNFAIP8、HSD17B4、FAM170A、PRR16、FTMT、SRFBP1、LOX、ZNF474、LOC100505841、SNCAIP、MGC32805、SNX2、SNX24、PPIC、PRDM6、CEP120、CSNK1G3、ZNF608、GRAMD3、ALDH7A1、PHAX、C5orf48、LMNB1、MARCH3、C5orf63、MEGF10、PRRC1、CTXN3、LOC728586、FLJ33630、SLC12A2、FBN2、SLC27A6、ISOC1、MIR4633、MIR4460、ADAMTS19、
KIAA1024L、CHSY3、HINT1、LYRM7、CDC42SE2、RAPGEF6、FNIP1、LOC728637、ACSL6、IL3、CSF2、P4HA2、PDLIM4、SLC22A4、LOC553103、MIR3936、SLC22A5、C5orf56、IRF1、IL5、RAD50、IL13、IL4、KIF3A、CCNI2、SEPT8、SOWAHA、SHROOM1、GDF9、UQCRQ、LEAP2、AFF4、ZCCHC10、HSPA4、LOC100506102、FSTL4、MIR1289-2、C5orf15、VDAC1、TCF7、SKP1、PPP2CA、MIR3661、CDKL3、UBE2B、CDKN2AIPNL、PHF15、SAR1B、SEC24A、CAMLG、DDX46、C5orf24、TXNDC15、PCBD2、MIR4461、CATSPER3、PITX1、LOC100996485、LOC340073、H2AFY、C5orf20、TIFAB、NEUROG1、CXCL14、LOC340074、MIR5692C1、SLC25A48、IL9、FBXL21、LECT2、TGFBI、VTRNA2-1、SMAD5-AS1、SMAD5、LOC389332、LOC100506219、TRPC7、SPOCK1、KLHL3、MIR874、HNRNPA0、NPY6R、MYOT、PKD2L2、FAM13B、LOC100130172、WNT8A、NME5、BRD8、KIF20A、CDC23、GFRA3、CDC25C、FAM53C、KDM3B、REEP2、EGR1、ETF1、HSPA9、SNORD63、CTNNA1、LRRTM2、SIL1、MATR3、SNHG4、SNORA74A、PAIP2、SLC23A1、MZB1、PROB1、SPATA24、DNAJC18、ECSCR、TMEM173、UBE2D2、CXXC5、PSD2、NRG2、LOC100505636、PURA、IGIP、CYSTM1、PFDN1、HBEGF、SLC4A9、ANKHD1、ANKHD1-EIF4EBP3、EIF4EBP3、SRA1、APBB3、SLC35A4、CD14、TMCO6、NDUFA2、IK、MIR3655、WDR55、DND1、HARS、HARS2、ZMAT2、VTRNA1-1、VTRNA1-2、VTRNA1-3、PCDHA1、PCDHA2、PCDHA3、PCDHA4、PCDHA5、PCDHA6、PCDHA7、PCDHA8、PCDHA9、PCDHA10、PCDHA11、PCDHA12、PCDHA13、PCDHAC1、PCDHAC2、PCDHB1、PCDHB2、PCDHB3、PCDHB4、PCDHB5、PCDHB6、PCDHB17、PCDHB7、PCDHB8、PCDHB16、PCDHB9、PCDHB10、PCDHB11、PCDHB12、PCDHB13、PCDHB14、PCDHB18、PCDHB19P、PCDHB15、SLC25A2、TAF7、PCDHGA1、PCDHGA2、PCDHGA3、PCDHGB1、PCDHGA4、PCDHGB2、PCDHGA5、PCDHGB3、PCDHGA6、PCDHGA7、PCDHGB4、PCDHGA8、PCDHGB5、PCDHGA9、PCDHGB6、PCDHGA10、PCDHGB7、PCDHGA11、PCDHGB8P、PCDHGA12、PCDHGC3、PCDHGC4、PCDHGC5、DIAPH1、LOC100505658、HDAC3、RELL2、FCHSD1、ARAP3、PCDH1、LOC729080、KIAA0141、PCDH12、RNF14、GNPDA1、NDFIP1、SPRY4、FGF1、ARHGAP26、ARHGAP26-AS1、NR3C1、MIR5197、HMHB1、YIPF5、KCTD16、PRELID2、GRXCR2、SH3RF2、PLAC8L1、LARS、RBM27、POU4F3、TCERG1、GPR151、PPP2R2B、PPP2R2B-IT1、STK32A、DPYSL3、JAKMIP2-AS1、JAKMIP2、SPINK1、SCGB3A2、C5orf46、SPINK5、SPINK14、SPINK6、SPINK13、SPINK7、SPINK9、FBXO38、HTR4、ADRB2、SH3TC2、MIR584、LOC255187、ABLIM3、AFAP1L1、GRPEL2、PCYOX1L、IL17B、MIR143HG、MIR143、MIR145、CSNK1A1、ARHGEF37、PPARGC1B、MIR378A、PDE6A、SLC26A2、TIGD6、HMGXB3、CSF1R、PDGFRB、CDX1、SLC6A7、CAMK2A、ARSI、TCOF1、CD74、RPS14、NDST1、SYNPO、MYOZ3、RBM22、DCTN4、SMIM3、IRGM、ZNF300、ZNF300P1、GPX3、TNIP1、ANXA6、CCDC69、GM2A、SLC36A3、SLC36A2、SLC36A1、
FAT2、SPARC、ATOX1、LOC100652758、G3BP1、GLRA1、NMUR2、GRIA1、FAM114A2、MFAP3、GALNT10、MIR1294、FLJ38109、SAP30L、HAND1、MIR3141、MIR1303、LARP1、C5orf4、MIR378H、CNOT8、GEMIN5、MRPL22、KIF4B、SGCD、PPP1R2P3、TIMD4、HAVCR1、HAVCR2、MED7、FAM71B、ITK、CYFIP2、FNDC9、NIPAL4、ADAM19、SOX30、C5orf52、THG1L、LSM11、CLINT1、LOC100507161、EBF1、RNF145、UBLCP1、IL12B、LOC285626、LOC285627、ADRA1B、TTC1、PWWP2A、FABP6、CCNJL、C1QTNF2、C5orf54、SLU7、PTTG1、MIR3142、MIR146A、ATP10B、LOC285629、GABRB2、GABRA6、GABRA1、GABRG2、CCNG1、NUDCD2、HMMR、MAT2B、TENM2、WWC1、RARS、FBLL1、PANK3、MIR103A1、MIR103B1、SLIT3、MIR218-2、LOC728095、MIR585、SPDL1、DOCK2、FAM196B、LOC100133106、MIR378E、FOXI1、LOC100507267、C5orf58、LCP2、LOC100128059、LOC257358、KCNIP1、KCNMB1、GABRP、RANBP17、LOC728145、TLX3、MIR3912、NPM1、FGF18、FBXW11、STK10、EFCAB9、UBTD2、SH3PXD2B、NEURL1B、MIR5003、DUSP1、ERGIC1、LOC100268168、RPL26L1、ATP6V0E1、SNORA74B、CREBRF、BNIP1、NKX2-5、STC2、LOC285593、BOD1、CPEB4、C5orf47、HMP19、MSX2、MIR4634、FLJ16171、DRD1、SFXN1、HRH2、CPLX2、THOC3、LOC100996385、FAM153B、LOC100507387、LOC643201、SIMC1、KIAA1191、ARL10、MIR1271、NOP16、HIGD2A、CLTB、FAF2、RNF44、CDHR2、GPRIN1、SNCB、MIR4281、EIF4E1B、TSPAN17、UNC5A、HK3、UIMC1、ZNF346、FGFR4、NSD1、RAB24、PRELID1、MXD3、LMAN2、RGS14、SLC34A1、PFN3、F12、GRK6、PRR7-AS1、PRR7、DBN1、PDLIM7、DOK3、DDX41、FAM193B、TMED9、B4GALT7、LOC202181、LOC100507427、FAM153A、LOC728554、LOC100128340、PROP1、FAM153C、N4BP3、RMND5B、NHP2、GMCL1P1、HNRNPAB、AGXT2L2、COL23A1、CLK4、ZNF354A、AACSP1、ZNF354B、ZFP2、ZNF454、GRM6、ZNF879、ZNF354C、ADAMTS2、RUFY1、HNRNPH1、C5orf60、CBY3、CANX、MAML1、LTC4S、MGAT4B、MIR1229、SQSTM1、C5orf45、LOC100996419、TBC1D9B、RNF130、MIR340、RASGEF1C、MAPK9、LOC100996424、GFPT2、CNOT6、SCGB3A1、FLT4、OR2Y1、MGAT1、LOC100859930、LOC729678、ZFP62、BTNL8、BTNL3、BTNL9、OR2V1、OR2V2、TRIM7、LOC100507546、MIR4638、TRIM41、GNB2L1、SNORD96A、SNORD95、TRIM52、LOC100507602、LOC100996446、LOC100132062、LOC100286914、OR4F3、FLJ43763、DUSP22、IRF4、EXOC2、HUS1B、LOC285768、FOXQ1、FOXF2、FOXC1、GMDS、LOC100508120、C6orf195、MYLK4、WRNIP1、SERPINB1、MIR4645、MGC39372、SERPINB9、SERPINB6、DKFZP686I15217、NQO2、HTATSF1P2、RIPK1、BPHL、TUBB2A、LOC100507194、TUBB2B、PSMG4、SLC22A23、PXDC1、FAM50B、PRPF4B、FAM217A、C6orf201、ECI2、LOC100507506、KU-MEL-3、CDYL、RPP40、LOC100129461、LOC100129033、PPP1R3G、LYRM4、MIR3691、FARS2、NRN1、F13A1、MIR5683、
LY86-AS1、LY86、RREB1、SSR1、CAGE1、RIOK1、DSP、SNRNP48、BMP6、TXNDC5、BLOC1S5-TXNDC5、PIP5K1P1、BLOC1S5、EEF1E1-MUTED、EEF1E1、SCARNA27、LOC100506091、SLC35B3、LOC100506207、HULC、LOC100506288、OFCC1、TFAP2A、LOC100130275、LINC00518、MIR5689、GCNT2、C6orf52、PAK1IP1、TMEM14C、LOC100506379、TMEM14B、MAK、GCM2、SYCP2L、ELOVL2、ELOVL2-AS1、C6orf228、ERVFRD-1、NEDD9、LOC100506431、TMEM170B、ADTRP、HIVEP1、EDN1、PHACTR1、LOC100130357、TBC1D7、GFOD1、SIRT5、NOL7、RANBP9、CCDC90A、RNF182、CD83、LOC100506631、LOC100506647、JARID2、JARID2-AS1、DTNBP1、MYLIP、MIR4639、GMPR、ATXN1、FLJ23152、RBM24、CAP2、FAM8A1、NUP153、KIF13A、LOC100996300、NHLRC1、TPMT、KDM1B、DEK、RNF144B、MIR548A1、LOC100506885、ID4、MBOAT1、E2F3、CDKAL1、SOX4、LINC00340、LOC729177、PRL、HDGFL1、NRSN1、DCDC2、KAAG1、MRS2、GPLD1、ALDH5A1、KIAA0319、TDP2、ACOT13、C6orf62、GMNN、FAM65B、CMAHP、LRRC16A、SCGN、HIST1H2AA、HIST1H2BA、HIST1H2APS1、SLC17A4、SLC17A1、SLC17A3、SLC17A2、TRIM38、HIST1H1A、HIST1H3A、HIST1H4A、HIST1H4B、HIST1H3B、HIST1H2AB、HIST1H2BB、HIST1H3C、HIST1H1C、HFE、HIST1H4C、HIST1H1T、HIST1H2BC、HIST1H2AC、HIST1H1E、HIST1H2BD、HIST1H2BE、HIST1H4D、HIST1H3D、HIST1H2AD、HIST1H2BF、HIST1H4E、HIST1H2BG、HIST1H2AE、HIST1H3E、HIST1H1D、HIST1H4F、HIST1H4G、HIST1H3F、HIST1H2BH、HIST1H3G、HIST1H2BI、HIST1H4H、BTN3A2、BTN2A2、BTN3A1、BTN2A3P、BTN3A3、BTN2A1、LOC285819、BTN1A1、HCG11、HMGN4、ABT1、ZNF322、GUSBP2、LINC00240、LOC100270746、HIST1H2BJ、HIST1H2AG、HIST1H2BK、HIST1H4I、HIST1H2AH、MIR3143、PRSS16、POM121L2、VN1R10P、ZNF204P、ZNF391、ZNF184、LOC100507173、LOC100131289、HIST1H2BL、HIST1H2AI、HIST1H3H、HIST1H2AJ、HIST1H2BM、HIST1H4J、HIST1H4K、HIST1H2AK、HIST1H2BN、HIST1H2AL、HIST1H1B、HIST1H3I、HIST1H4L、HIST1H3J、HIST1H2AM、HIST1H2BO、OR2B2、OR2B6、ZNF165、ZSCAN12P1、ZSCAN16、ZNF192、TOB2P1、ZNF193、ZKSCAN4、NKAPL、ZNF187、PGBD1、ZNF323、ZKSCAN3、ZSCAN12、ZSCAN23、GPX6、GPX5、SCAND3、LOC401242、TRIM27、ZNF311、LOC100129636、OR2W1、OR2B3、OR2J3、OR2J2、OR14J1、OR5V1、OR12D3、OR12D2、OR11A1、OR10C1、OR2H1、MAS1L、LOC100507362、UBD、SNORD32B、OR2H2、GABBR1、MOG、ZFP57、HLA-F、HLA-F-AS1、IFITM4P、HCG4、LOC554223、HLA-G、HLA-H、HCG4B、HLA-A、HCG9、ZNRD1-AS1、HLA-J、HCG8、ZNRD1、PPP1R11、RNF39、TRIM31、TRIM40、TRIM10、TRIM15、TRIM26、HCG17、HLA-L、HCG18、TRIM39、TRIM39-RPP21、RPP21、HLA-E、GNL1、PRR3、ABCF1、MIR877、PPP1R10、MRPS18B、ATAT1、C6orf136、DHX16、PPP1R18、NRM、MDC1、TUBB、FLOT1、IER3、LINC00243、DDR1、
MIR4640、GTF2H4、VARS2、SFTA2、DPCR1、MUC21、MUC22、HCG22、C6orf15、PSORS1C1、CDSN、PSORS1C2、CCHCR1、TCF19、POU5F1、PSORS1C3、HCG27、LOC100996357、HLA-C、HLA-B、MICA、HCP5、HCG26、MICB、MCCD1、ATP6V1G2-DDX39B、DDX39B、SNORD117、SNORD84、ATP6V1G2、NFKBIL1、LOC100287329、LTA、TNF、LTB、LST1、NCR3、AIF1、PRRC2A、SNORA38、BAG6、APOM、C6orf47、GPANK1、CSNK2B、LY6G5B、LY6G5C、ABHD16A、MIR4646、LY6G6F、LY6G6E、LY6G6D、LY6G6C、C6orf25、DDAH2、CLIC1、MSH5、MSH5-SAPCD1、SAPCD1、VWA7、VARS、LSM2、HSPA1L、HSPA1A、HSPA1B、C6orf48、SNORD48、SNORD52、NEU1、SLC44A4、EHMT2、C2、ZBTB12、CFB、RDBP、MIR1236、SKIV2L、DOM3Z、STK19、C4A、CYP21A1P、TNXA、C4B、CYP21A2、TNXB、ATF6B、FKBPL、PRRT1、LOC100507547、PPT2、PPT2-EGFL8、EGFL8、AGPAT1、RNF5、AGER、PBX2、GPSM3、NOTCH4、C6orf10、HCG23、BTNL2、HLA-DRA、HLA-DRB5、HLA-DRB6、HLA-DRB1、HLA-DQA1、HLA-DQB1、HLA-DQA2、MIR3135B、HLA-DQB2、HLA-DOB、TAP2、PSMB8、LOC100507463、TAP1、PSMB9、LOC100294145、HLA-DMB、HLA-DMA、BRD2、HLA-DOA、HLA-DPA1、HLA-DPB1、HLA-DPB2、COL11A2、RXRB、SLC39A7、HSD17B8、MIR219-1、RING1、HCG25、VPS52、RPS18、B3GALT4、WDR46、PFDN6、RGL2、TAPBP、ZBTB22、DAXX、KIFC1、PHF1、CUTA、SYNGAP1、MIR5004、ZBTB9、BAK1、GGNBP1、LINC00336、ITPR3、MNF1、MIR3934、IP6K3、LEMD2、MLN、LOC100507584、LOC100653005、MIR1275、GRM4、HMGA1、C6orf1、NUDT3、RPS10-NUDT3、RPS10、PACSIN1、SPDEF、C6orf106、SNRPC、UHRF1BP1、TAF11、ANKS1A、TCP11、SCUBE3、ZNF76、DEF6、PPARD、LOC100507672、FANCE、RPL10A、TEAD3、TULP1、FKBP5、MIR5690、LOC285847、ARMC12、CLPSL2、CLPSL1、CLPS、LHFPL5、SRPK1、SLC26A8、MAPK14、MAPK13、BRPF3、PNPLA1、C6orf222、ETV7、PXT1、KCTD20、STK38、SRSF3、MIR3925、CDKN1A、RAB44、CPNE5、PPIL1、C6orf89、PI16、MTCH1、FGD2、PIM1、TMEM217、TBC1D22B、RNF8、FTSJD2、CCDC167、FLJ45825、LOC100505550、MIR4462、MDGA1、ZFAND3、BTBD9、GLO1、DNAH8、LOC100131047、GLP1R、SAYSD1、KCNK5、KCNK17、KCNK16、KIF6、DAAM2、LOC100505635、MOCS1、FLJ41649、TDRG1、LRFN2、LOC100505697、UNC5CL、TSPO2、APOBEC2、OARD1、NFYA、ADCY10P1、TREML1、TREM2、TREML2、TREML3P、TREML4、TREML5P、TREM1、NCR2、LOC100505711、FOXP4、MIR4641、MDFI、TFEB、PGC、FRS3、PRICKLE4、TOMM6、USP49、MED20、BYSL、CCND3、TAF8、C6orf132、GUCA1A、GUCA1B、MRPS10、TRERF1、UBR2、PRPH2、ATP6V0CP3、TBCC、KIAA0240、RPL7L1、C6orf226、PTCRA、CNPY3、GNMT、PEX6、PPP2R5D、MEA1、KLHDC3、RRP36、CUL7、MRPL2、KLC4、PTK7、SRF、CUL9、C6orf108、TTBK1、SLC22A7、CRIP3、ZNF318、ABCC10、DLK2、TJAP1、LRRC73、YIPF3、POLR1C、XPO5、POLH、
GTPBP2、MAD2L1BP、RSPH9、MRPS18A、VEGFA、LOC100132354、C6orf223、MRPL14、TMEM63B、CAPN11、SLC29A1、HSP90AB1、SLC35B2、MIR4647、NFKBIE、TMEM151B、TCTE1、AARS2、SPATS1、CDC5L、MIR4642、LOC100505862、SUPT3H、MIR586、RUNX2、CLIC5、ENPP4、ENPP5、RCAN2、CYP39A1、SLC25A27、TDRD6、PLA2G7、LOC100287718、MEP1A、GPR116、GPR110、TNFRSF21、CD2AP、GPR111、GPR115、OPN5、PTCHD4、MUT、CENPQ、GLYATL3、C6orf141、RHAG、CRISP2、CRISP3、PGK2、CRISP1、DEFB133、DEFB114、DEFB113、DEFB110、DEFB112、LOC100505985、TFAP2D、TFAP2B、PKHD1、MIR206、MIR133B、IL17A、IL17F、MCM3、PAQR8、EFHC1、TRAM2、FLJ37798、LOC730101、TMEM14A、GSTA7P、GSTA2、GSTA1、GSTA5、GSTA3、GSTA4、RN7SK、ICK、FBXO9、GCM1、ELOVL5、MIR5685、RPS16P5、GCLC、KLHL31、LRRC1、MLIP-IT1、MLIP、TINAG、FAM83B、HCRTR2、GFRAL、HMGCLL1、BMP5、COL21A1、DST、LOC100652766、BEND6、KIAA1586、ZNF451、BAG2、RAB23、LOC100506188、MIR548U、GUSBP4、LOC100996497、KHDRBS2、LGSN、PTP4A1、PHF3、EYS、SLC25A51P1、LOC100996552、BAI3、LMBRD1、COL19A1、COL9A1、LOC100507172、FAM135A、C6orf57、SMAP1、B3GAT2、OGFRL1、LOC100507367、MIR30C2、MIR30A、LINC00472、RIMS1、KCNQ5、KCNQ5-IT1、MIR4282、KCNQ5-AS1、KHDC1L、KHDC1、C6orf147、DPPA5、KHDC3L、OOEP、DDX43、MB21D1、MTO1、EEF1A1、SLC17A5、CD109、COL12A1、COX7A2、TMEM30A、LOC100506804、FILIP1、MIR4463、SENP6、MYO6、IMPG1、HTR1B、IRAK1BP1、PHIP、HMGN3、LOC100288198、LOC100506851、LCA5、SH3BGRL2、C6orf7、ELOVL4、TTK、BCKDHB、FAM46A、IBTK、TPBG、UBE3D、DOPEY1、PGM3、RWDD2A、ME1、PRSS35、SNAP91、RIPPLY2、CYB5R4、LOC100506908、MRAP2、KIAA1009、LOC100506926、TBX18、NT5E、SNX14、SYNCRIP、SNHG5、SNORD50A、SNORD50B、HTR1E、CGA、ZNF292、GJB7、C6orf162、C6orf163、C6orf164、C6orf165、SLC35A1、RARS2、ORC3、AKIRIN2、SPACA1、CNR1、RNGTT、PNRC1、SRSF12、PM20D2、GABRR1、GABRR2、UBE2J1、RRAGD、ANKRD6、LYRM2、MDN1、CASP8AP2、GJA10、LOC100507024、BACH2、MIR4464、MAP3K7、MIR4643、EPHA7、TSG1、MANEA、FUT9、UFL1、FHL5、GPR63、NDUFAF4、KLHL32、MMS22L、MIR2113、POU3F2、FBXL4、MIR548AI、FAXC、COQ3、PNISR、USP45、TSTD3、CCNC、PRDM13、MCHR2、LOC728012、SIM1、ASCC3、GRIK2、HACE1、LINC00577、LIN28B、BVES、BVES-AS1、POPDC3、PREP、PRDM1、ATG5、LOC100506165、AIM1、RTN4IP1、QRSL1、LOC100422737、MIR587、C6orf203、BEND3、PDSS2、SOBP、SCML4、SEC63、OSTM1、OSTM1-AS1、NR2E1、SNX3、LACE1、FOXO3、LINC00222、ARMC2、LOC100506276、SESN1、CEP57L1、C6orf183、LOC100996634、CCDC162P、LOC100996641、CD164、PPIL6、SMPD2、MICAL1、ZBTB24、AKD1、FIG4、GPR6、WASF1、
CDC40、METTL24、DDO、SLC22A16、CDK19、AMD1、GTF3C6、RPF2、GSTM2P1、SLC16A10、KIAA1919、REV3L、TRAF3IP2-AS1、TRAF3IP2、FYN、LOC100506389、WISP3、TUBE1、C6orf225、LAMA4、RFPL4B、LOC100287612、LOC100652953、MARCKS、LOC285758、FLJ34503、HDAC2、HS3ST5、LOC441167、FRK、TPI1P3、NT5DC1、COL10A1、TSPYL4、LOC100506496、TSPYL1、DSE、FAM26F、BET3L、FAM26E、FAM26D、RWDD1、RSPH4A、ZUFSP、KPNA5、FAM162B、GPRC6A、RFX6、VGLL2、ROS1、DCBLD1、GOPC、NUS1、SLC35F1、CEP85L、BRD7P3、PLN、LOC100287632、MCM9、ASF1A、FAM184A、MIR548B、MAN1A1、LOC285762、MIR3144、C6orf170、GJA1、HSF2、SERINC1、PKIB、FABP7、SMPDL3A、CLVS2、TRDN、NKAIN2、STL、RNF217、TPD52L1、HDDC2、LOC643623、HEY2、NCOA7、HINT3、TRMT11、LOC100507136、CENPW、MIR588、RSPO3、RNF146、ECHDC1、SOGA3、KIAA0408、C6orf58、THEMIS、PTPRK、LAMA2、ARHGAP18、TMEM244、L3MBTL3、SAMD3、TMEM200A、LOC100507203、EPB41L2、AKAP7、ARG1、MED23、ENPP3、OR2A4、CTAGE9、MIR548H5、ENPP1、CTGF、MIR548AJ1、LOC100507254、MOXD1、STX7、TAAR9、TAAR8、TAAR6、TAAR5、TAAR3、TAAR2、TAAR1、VNN1、VNN3、VNN2、SLC18B1、RPS12、SNORD101、SNORD100、SNORA33、LINC00326、EYA4、LOC100507308、MGC34034、TCF21、TBPL1、SLC2A12、HMGA1P7、SGK1、LOC154092、ALDH8A1、HBS1L、MIR3662、MYB、MIR548A2、AHI1、LINC00271、PDE7B、LOC644135、FAM54A、BCLAF1、MAP7、MAP3K5、PEX7、SLC35D3、NHEG1、IL20RA、IL22RA2、IFNGR1、OLIG3、LOC100507406、LOC100130476、TNFAIP3、PERP、KIAA1244、PBOV1、HEBP2、NHSL1、MIR3145、FLJ46906、LOC100507462、CCDC28A、ECT2L、REPS1、ABRACL、HECA、TXLNB、CITED2、LOC645434、LOC100132735、LOC100507477、MIR3668、MIR4465、NMBR、VTA1、GPR126、LOC153910、HIVEP2、LOC100507489、AIG1、ADAT2、PEX3、FUCA2、LOC285740、PHACTR2、LTV1、ZC2HC1B、PLAGL1、HYMAI、SF3B5、STX11、UTRN、EPM2A、LOC100507557、FBXO30、SHPRH、GRM1、RAB32、ADGB、LOC729176、STXBP5-AS1、STXBP5、SAMD5、SASH1、UST、LOC100128176、TAB2、SUMO4、ZC3H12D、PPIL4、GINM1、KATNA1、LATS1、NUP43、PCMT1、LRP11、LOC100652739、RAET1E、RAET1G、ULBP2、ULBP1、RAET1K、RAET1L、ULBP3、PPP1R14C、IYD、PLEKHG1、MTHFD1L、AKAP12、ZBTB2、RMND1、C6orf211、CCDC170、ESR1、SYNE1、SYNE1-AS1、MYCT1、VIP、FBXO5、MTRF1L、RGS17、LOC100996290、OPRM1、IPCEF1、CNKSR3、SCAF8、MIR1273C、LOC100505519、TIAM2、TFB1M、CLDN20、NOX3、MIR1202、ARID1B、MIR4466、TMEM242、ZDHHC14、MIR3692、SNX9、SYNJ2、SYNJ2-IT1、SERAC1、GTF2H5、TULP4、TMEM181、DYNLT1、SYTL3、MIR3918、EZR、OSTCP1、C6orf99、RSPH3、TAGAP、FNDC1、FLJ27255、SOD2、WTAP、LOC100129518、ACAT2、TCP1、SNORA20、SNORA29、MRPL18、
PNLDC1、MAS1、IGF2R、AIRN、LOC729603、SLC22A1、SLC22A2、SLC22A3、LPAL2、LPA、PLG、MAP3K4、AGPAT4、AGPAT4-IT1、PARK2、PACRG、LOC729658、PACRG-AS1、DKFZp451B082、CAHM、QKI、C6orf118、PDE10A、SDIM1、LINC00473、LINC00602、T、PRR18、SFT2D1、LOC100289495、MPC1、RPS6KA2、RPS6KA2-IT1、MIR1913、RNASET2、MIR3939、FGFR1OP、CCR6、GPR31、TCP10L2、UNC93A、TTLL2、TCP10、LOC729995、LOC401286、C6orf123、LOC441179、MLLT4-AS1、MLLT4、HGC6.3、KIF25-AS1、KIF25、FRMD1、DACT2、SMOC2、THBS2、WDR27、C6orf120、PHF10、TCTE3、C6orf70、LINC00242、LINC00574、LOC100505903、LOC154449、DLL1、FAM120B、MIR4644、PSMB1、TBP、PDCD2、LOC100132858、LOC100507642、FAM20C、LOC100996433、LOC100288524、LOC442497、LOC100131372、PDGFA、FLJ44511、PRKAR1B、HEATR2、SUN1、GET4、ADAP1、COX19、CYP2W1、C7orf50、MIR339、GPR146、GPER、ZFAND2A、UNCX、MICALL2、LOC100996269、INTS1、MAFK、LOC100128653、TMEM184A、PSMG3、PSMG3-AS1、TFAMP1、LOC401296、ELFN1、MAD1L1、LOC100128374、MIR4655、FTSJ2、NUDT1、SNX8、EIF3B、CHST12、LOC100288594、LFNG、MIR4648、BRAT1、IQCE、TTYH3、AMZ1、GNA12、CARD11、SDK1、FOXK1、AP5Z1、MIR4656、RADIL、PAPOLB、MMD2、RNF216P1、RBAK、RBAK-LOC389458、LOC389458、ZNF890P、WIPI2、SLC29A4、TNRC18、LOC100129484、FBXL18、MIR589、ACTB、FSCN1、RNF216、RNF216-IT1、ZNF815P、OCM、CCZ1、RSPH10B、PMS2、AIMP2、EIF2AK1、USP42、CYTH3、FAM220A、RAC1、DAGLB、KDELR2、GRID2IP、ZDHHC4、C7orf26、ZNF853、ZNF12、LOC100505863、PMS2CL、RSPH10B2、CCZ1B、MIR3683、LOC100131257、C1GALT1、LOC100505904、COL28A1、MIOS、RPA3、LOC729852、LOC100505921、GLCCI1、ICA1、LOC100505938、NXPH1、PER4、NDUFA4、PHF14、THSD7A、TMEM106B、VWDE、SCIN、ARL4A、ETV1、DGKB、AGMO、MEOX2、ISPD、LOC100506025、SOSTDC1、LRRC72、ANKMY2、BZW2、TSPAN13、AGR2、AGR3、AHR、SNX13、PRPS1L1、HDAC9、MIR1302-6、TWIST1、FERD3L、TWISTNB、MIR3146、TMEM196、MACC1、MACC1-AS1、LOC100506098、ITGB8、ABCB5、SP8、RPL23P8、SP4、MIR1183、DNAH11、CDCA7L、RAPGEF5、STEAP1B、LOC100506178、LOC401312、LOC541472、IL6、TOMM7、SNORD93、FAM126A、KLHL7-AS1、KLHL7、NUPL2、GPNMB、MALSU1、IGF2BP3、RPS2P32、TRA2A、CLK2P、CCDC126、FAM221A、STK31、NPY、MPP6、DFNA5、OSBPL3、CYCS、C7orf31、NPVF、LOC100506236、LOC100996355、MIR148A、NFE2L3、HNRNPA2B1、CBX3、SNX10、LOC441204、KIAA0087、LOC100506289、C7orf71、SKAP2、HOXA1、HOTAIRM1、HOXA2、HOXA3、HOXA-AS2、HOXA4、HOXA-AS3、HOXA5、HOXA6、HOXA7、HOXA9、HOXA10-HOXA9、HOXA-AS4、MIR196B、HOXA10、HOXA11、HOXA11-AS、HOXA13、HOTTIP、EVX1、HIBADH、TAX1BP1、JAZF1、JAZF1-AS1、CREB5、
LOC401317、TRIL、LOC100506497、CPVL、CHN2、PRR15、LOC646762、MIR550A3、ZNRF2P2、DPY19L2P3、WIPF3、SCRN1、FKBP14、PLEKHA8、C7orf41、ZNRF2、MIR550A1、MIR550B1、DKFZP586I1420、LOC100506516、NOD1、GGCT、LOC401320、GARS、CRHR2、INMT、INMT-FAM188B、FAM188B、AQP1、GHRHR、ADCYAP1R1、NEUROD6、CCDC129、PPP1R17、PDE1C、LOC100130673、LSM5、AVL9、DPY19L1P1、ZNRF2P1、MIR550B2、MIR550A2、LOC401321、KBTBD2、RP9P、FKBP9、NT5C3、RP9、BBS9、FLJ20712、BMPER、NPSR1-AS1、NPSR1、DPY19L1、MIR548N、DPY19L2P1、TBX20、LOC401324、HERPUD2、LOC100506725、SEPT7、PP13004、EEPD1、KIAA0895、ANLN、AOAH、AOAH-IT1、ELMO1、MIR1200、GPR141、NME8、SFRP4、EPDR1、STARD3NL、TARP、LOC100506776、AMPH、FAM183B、VPS41、POU6F2、POU6F2-AS1、YAE1D1、LOC100996411、LOC646999、RALA、LINC00265、CDK13、MPLKIP、C7orf10、INHBA、INHBA-AS1、GLI3、C7orf25、PSMA2、MRPL32、HECW1、HECW1-IT1、MIR3943、LOC100506895、STK17A、COA1、BLVRA、URGCP-MRPS24、MRPS24、URGCP、UBE2D4、POLR2J4、SPDYE1、RASA4CP、FLJ35390、DBNL、PGAM2、POLM、AEBP1、MIR4649、POLD2、MYL7、GCK、YKT6、CAMK2B、NUDCD3、NPC1L1、DDX56、TMED4、OGDH、ZMIZ2、PPIA、H2AFV、PURB、MIR4657、MYO1G、SNHG15、SNORA9、CCM2、NACAD、TBRG4、SNORA5A、SNORA5C、SNORA5B、RAMP3、ADCY1、SEPT7P2、IGFBP1、IGFBP3、TNS3、C7orf65、LINC00525、PKD1L1、C7orf69、HUS1、SUN3、C7orf57、UPP1、ABCA13、CDC14C、VWC2、ZPBP、C7orf72、IKZF1、FIGNL1、DDC、LOC100129427、GRB10、COBL、LOC730378、POM121L12、FLJ45974、HPVC1、VSTM2A、LOC285878、SEC61G、LOC100996654、EGFR、EGFR-AS1、LANCL2、VOPP1、FKBP9L、LOC730376、LOC100128326、SEPT14、ZNF713、MRPS17、GBAS、PSPH、CCT6A、SNORA15、SUMF2、PHKG1、CHCHD2、NUPR1L、LOC100507369、LOC650226、DKFZp434L192、LOC100996261、LOC100996271、LOC100996278、LOC100130849、LOC100287294、MIR4283-1、ZNF479、GUSBP10、MIR3147、ZNF716、LOC100287633、ZNF733P、LOC100287704、LOC100287834、MIR4283-2、LOC402269、LOC100287894、LOC100996408、LOC100996423、LOC100996380、LOC100506050、ZNF727、ZNF735、ZNF679、ZNF736、LOC649395、ZNF680、LOC641746、ZNF107、ZNF138、ZNF273、ZNF117、ERV3-1、CCT6P3、ZNF92、LOC441242、INTS4L2、LOC100996422、CCT6P1、SNORA22、DKFZP434F142、VKORC1L1、GUSB、ASL、CRCP、TPST1、LINC00174、LOC100289098、LOC493754、KCTD7、LOC100996437、RABGEF1、GTF2IRD1P1、LOC644794、TMEM248、SBDS、TYW1、MIR4650-1、PMS2P4、STAG3L4、LOC100507468、AUTS2、WBSCR17、MIR3914-1、MIR3914-2、CALN1、TYW1B、MIR4650-2、SBDSP1、SPDYE7P、POM121、NSUN5P2、TRIM74、STAG3L3、SPDYE8P、LOC100093631、NCF1B、GTF2IRD2P1、
NSUN5、TRIM50、FKBP6、FZD9、BAZ1B、BCL7B、TBL2、MLXIPL、VPS37D、DNAJC30、WBSCR22、STX1A、MIR4284、ABHD11-AS1、ABHD11、CLDN3、CLDN4、LOC100996451、WBSCR27、WBSCR28、ELN、LIMK1、EIF4H、MIR590、LAT2、RFC2、CLIP2、GTF2IRD1、GTF2I、NCF1、GTF2IRD2、STAG3L2、PMS2P5、GATSL1、LOC100505669、WBSCR16、GTF2IRD2B、NCF1C、GTF2IP1、GATSL2、PMS2L2、STAG3L1、LOC541473、TRIM73、NSUN5P1、POM121C、SPDYE5、PMS2P3、HIP1、CCL26、CCL24、RHBDD2、POR、MIR4651、SNORA14A、TMEM120A、STYXL1、MDH2、SRRM3、HSPB1、YWHAG、SRCRB4D、ZP3、DTX2、FDPSL2A、UPK3B、LOC100288807、LOC100133091、POMZP3、DTX2P1-UPK3BP1-PMS2P11、LOC100132832、LOC100505767、CCDC146、FGL2、PION、PTPN12、RSBN1L-AS1、RSBN1L、TMEM60、PHTF2、MAGI2、RPL13AP17、MAGI2-AS2、MAGI2-AS3、GNAI1、GNAT3、CD36、SEMA3C、HGF、CACNA2D1、PCLO、SEMA3E、SEMA3A、SEMA3D、LOC100505913、GRM3、KIAA1324L、DMTF1、C7orf23、TP53TG1、CROT、ABCB4、ABCB1、RUNDC3B、SLC25A40、DBF4、ADAM22、SRI、STEAP4、ZNF804B、C7orf62、DPY19L2P4、STEAP1、STEAP2、C7orf63、GTPBP10、CLDN12、LOC100996527、CDK14、FZD1、MTERF、AKAP9、CYP51A1、LOC613126、LRRD1、KRIT1、MIR1285-1、ANKIB1、GATAD1、ERVW-1、PEX1、RBM48、MGC16142、FAM133B、CDK6、RNU6-10、SAMD9、SAMD9L、HEPACAM2、CCDC132、CALCR、MIR653、MIR489、MIR4652、TFPI2、GNGT1、GNG11、BET1、COL1A2、CASD1、SGCE、PEG10、PPP1R9A、PON1、PON3、PON2、ASB4、LOC100996577、PDK4、DYNC1I1、SLC25A13、MIR591、FLJ42280、LOC100506136、SHFM1、DLX6-AS1、DLX6、DLX5、ACN9、TAC1、ASNS、MIR5692A1、MIR5692C2、MGC72080、OCM2、LMTK2、BHLHA15、TECPR1、BRI3、BAIAP2L1、FLJ30064、NPTX2、TMEM130、TRRAP、MIR3609、SMURF1、KPNA7、MYH16、ARPC1A、ARPC1B、PDAP1、BUD31、PTCD1、ATP5J2-PTCD1、CPSF4、ATP5J2、ZNF789、ZNF394、ZKSCAN5、FAM200A、ZNF655、LOC100289187、ZNF498、CYP3A5、CYP3A7-CYP3AP1、CYP3A7、CYP3A4、CYP3A43、OR2AE1、TRIM4、GJC3、AZGP1、AZGP1P1、ZKSCAN1、ZSCAN21、ZNF3、COPS6、MCM7、MIR25、MIR93、MIR106B、AP4M1、TAF6、CNPY4、MBLAC1、LAMTOR4、C7orf43、MIR4658、GAL3ST4、GPC2、STAG3、GATS、PVRIG、SPDYE3、PMS2P1、PILRB、PILRA、ZCWPW1、MEPCE、PPP1R35、C7orf61、TSC22D4、NYAP1、AGFG2、SAP25、LRCH4、FBXO24、PCOLCE-AS1、PCOLCE、MOSPD3、TFR2、ACTL6B、GNB2、GIGYF1、POP7、EPO、ZAN、EPHB4、SLC12A9、TRIP6、SRRT、UFSP1、ACHE、MUC12、MUC17、TRIM56、SERPINE1、AP1 S1、MIR4653、VGF、NAT16、MOGAT3、PLOD3、ZNHIT1、CLDN15、FIS1、RABL5、EMID2、LOC100506527、MYL10、CUX1、SH2B2、MIR4285、SPDYE6、LOC100630923、LOC100289561、PRKRIP1、MIR548O、ORAI2、ALKBH4、LRWD1、MIR5090、MIR4467、POLR2J、RASA4B、POLR2J3、SPDYE2、RASA4、
POLR2J2、UPK3BL、SPDYE2L、FAM185A、FBXL13、LRRC17、NFE4、ARMC10、NAPEPLD、RPL19P12、DPY19L2P2、PMPCB、DNAJC2、PSMC2、SLC26A5、RELN、ORC5、LHFPL3、LHFPL3-AS1、LHFPL3-AS2、LOC100216546、LOC100216545、MLL5、SRPK2、PUS7、RINT1、EFCAB10、ATXN7L1、CDHR3、SYPL1、NAMPT、CCDC71L、PIK3CG、PRKAR2B、HBP1、COG5、GPR22、DUS4L、BCAP29、SLC26A4-AS1、SLC26A4、CBLL1、SLC26A3、DLD、LAMB1、LAMB4、NRCAM、PNPLA8、THAP5、DNAJB9、C7orf66、EIF3IP1、IMMP2L、LRRN3、DOCK4、LOC100506413、ZNF277、IFRD1、C7orf53、LOC100996249、TMEM168、C7orf60、GPR85、LOC401397、TSRM、PPP1R3A、FOXP2、MIR3666、MDFIC、LOC100506489、TFEC、TES、CAV2、CAV1、LOC100996266、MET、CAPZA2、ST7-AS1、ST7、ST7-OT4、ST7-AS2、ST7-OT3、WNT2、ASZ1、CFTR、CTTNBP2、NAA38、ANKRD7、KCND2、TSPAN12、ING3、CPED1、WNT16、FAM3C、PTPRZ1、AASS、FEZF1、FEZF1-AS1、CADPS2、RNF133、RNF148、TAS2R16、SLC13A1、IQUB、NDUFA5、ASB15、LMOD2、WASL、HYALP1、HYAL4、SPAM1、TMEM229A、GPR37、LOC154872、POT1、LOC100506664、GRM8、MIR592、ZNF800、LOC100506682、GCC1、ARF5、FSCN3、PAX4、SND1、SND1-IT1、LRRC4、MIR593、MIR129-1、LEP、MGC27345、RBM28、PRRT4、IMPDH1、HILPDA、METTL2B、FLJ45340、FAM71F2、FAM71F1、CALU、OPN1SW、CCDC136、FLNC、ATP6V1F、LOC100130705、KCP、IRF5、TNPO3、TPI1P2、LOC407835、TSPAN33、SMO、AHCYL2、STRIP2、LOC100287482、NRF1、RNA5SP244、MIR182、MIR96、MIR183、UBE2H、ZC3HC1、KLHDC10、TMEM209、C7orf45、CPA2、CPA4、CPA5、CPA1、CEP41、MEST、MESTIT1、MIR335、COPG2、TSGA13、KLF14、MIR29A、MIR29B1、LOC646329、LOC100506860、FLJ43663、MKLN1、LOC100506881、PODXL、PLXNA4、FLJ40288、LOC100506937、CHCHD3、MIR3654、EXOC4、LRGUK、SLC35B4、AKR1B1、AKR1B10、AKR1B15、BPGM、CALD1、AGBL3、LOC653739、TMEM140、C7orf49、WDR91、STRA8、CNOT4、NUP205、C7orf73、SLC13A4、FAM180A、LUZP6、MTPN、CHRM2、LOC349160、MIR490、PTN、DGKI、NAG20、CREB3L2、LOC100130880、AKR1D1、MIR4468、TRIM24、SVOPL、ATP6V0A4、TMEM213、KIAA1549、ZC3HAV1L、ZC3HAV1、TTC26、UBN2、LUC7L2、C7orf55、C7orf55-LUC7L2、PP12708、LOC100129148、KLRG2、CLEC2L、HIPK2、TBXAS1、PARP12、JHDM1D、LOC100134229、SLC37A3、RAB19、MKRN1、DENND2A、ADCK2、NDUFB2-AS1、NDUFB2、BRAF、MRPS33、TMEM178B、LOC100130169、AGK、KIAA1147、FLJ40852、WEE2、SSBP1、TAS2R3、TAS2R4、TAS2R5、PRSS37、OR9A4、CLEC5A、TAS2R38、MGAM、LOC93432、MOXD2P、PRSS58、MTRNR2L6、PRSS1、PRSS3P2、EPHB6、TRPV6、TRPV5、C7orf34、KEL、OR9A2、OR6V1、OR6W1P、PIP、TAS2R39、TAS2R40、GSTK1、TMEM139、CASP2、CLCN1、FAM131B、LOC100507507、ZYX、EPHA1、EPHA1-AS1、TAS2R60、TAS2R41、CTAGE15P、FAM115C、
CTAGE6P、LOC154761、FAM115A、OR2F2、OR2F1、OR6B1、OR2A5、OR2A25、OR2A12、OR2A2、OR2A14、CTAGE4、ARHGEF35、OR2A42、OR2A20P、OR2A7、LOC728377、OR2A9P、OR2A1、ARHGEF5、NOBOX、TPK1、CNTNAP2、MIR548F4、LOC100507538、C7orf33、CUL1、EZH2、RNY5、RNY4、RNY3、RNY1、PDIA4、ZNF786、ZNF425、ZNF398、ZNF282、ZNF212、ZNF783、LOC155060、ZNF777、ZNF746、ZNF767、KRBA1、ZNF467、SSPO、ZNF862、ATP6V0E2-AS1、ATP6V0E2、LOC100996256、LOC100134040、ACTR3C、LRRC61、C7orf29、RARRES2、REPIN1、ZNF775、LOC728743、LOC285972、GIMAP8、GIMAP7、GIMAP4、GIMAP6、GIMAP2、GIMAP1、GIMAP1-GIMAP5、GIMAP5、TMEM176B、TMEM176A、ABP1、KCNH2、NOS3、ATG9B、ABCB8、ASIC3、CDK5、SLC4A2、LOC100996677、FASTK、TMUB1、AGAP3、GBX1、ASB10、ABCF2、CHPF2、MIR671、SMARCD3、NUB1、WDR86、WDR86-AS1、CRYGN、MIR3907、RHEB、PRKAG2、LOC644090、PRKAG2-AS1、GALNTL5、GALNT11、MLL3、FABP5P3、LOC100128822、XRCC2、ACTR3B、DPP6、LOC100996700、LOC100132707、PAXIP1、LOC202781、LOC100128264、HTR5A、LOC100996388、INSIG1、EN2、CNPY1、LOC100506302、RBM33、SHH、LOC100996445、LOC389602、LOC285889、LOC100506380、LINC00244、C7orf13、RNF32、LMBR1、NOM1、MNX1、LOC645249、LOC100996426、UBE3C、LOC100506458、DNAJB6、LOC100506534、LOC100506557、PTPRN2、MIR153-2、LOC100506585、MIR595、MIR5707、NCAPG2、ESYT2、WDR60、LINC00689、VIPR2、OR4F21、RPL23AP53、ZNF596、FAM87A、FBXO25、C8orf42、LOC100996633、LOC389607、ERICH1、LOC401442、LOC286083、DLGAP2、LOC100507435、CLN8、MIR3674、MIR596、ARHGEF10、LOC100131395、KBTBD11、MYOM2、CSMD1、LOC100287015、MCPH1、ANGPT2、LOC100507530、AGPAT5、MIR4659A、MIR4659B、XKR5、LOC100652791、DEFB1、DEFA6、DEFA4、DEFA10P、DEFA1、DEFT1P、DEFA1B、DEFT1P2、DEFA3、DEFA5、LOC349196、FAM66B、DEFB109P1B、USP17L1P、USP17L4、ZNF705G、DEFB4B、DEFB103B、SPAG11B、DEFB104B、DEFB106B、DEFB105B、DEFB107B、LOC100131608、FAM90A7P、FAM90A10P、LOC100133251、DEFB107A、DEFB105A、DEFB106A、DEFB104A、SPAG11A、DEFB103A、DEFB4A、ZNF705B、FAM66E、USP17L8、USP17L3、LOC100132046、MIR548I3、FAM86B3P、SGK223、CLDN23、MFHAS1、ERI1、MIR4660、PPP1R3B、LOC157273、TNKS、MIR597、LINC00599、MIR124-1、MSRA、PRSS55、RP1L1、MIR4286、C8orf74、SOX7、PINX1、MIR1322、XKR6、MIR598、MTMR9、SLC35G5、TDH、C8orf12、FAM167A、BLK、LINC00208、GATA4、C8orf49、NEIL2、FDFT1、CTSB、DEFB136、DEFB135、DEFB134、LOC100133267、ZNF705D、FAM66D、LOC392196、USP17L7、USP17L2、FAM90A2P、FAM86B1、FAM85A、DEFB130、FAM66A、LOC649352、DEFB109P1、FAM86B2、LOC100506990、LOC729732、MIR5692A2、LONRF1、MIR3926-1、MIR3926-2、LOC340357、KIAA1456、DLC1、C8orf48、SGCZ、MIR383、TUSC3、MSR1、FGF20、EFHA2、ZDHHC2、CNOT7、VPS37A、MTMR7、SLC7A2、PDGFRL、MTUS1、MIR548V、FGL1、PCM1、ASAH1、NAT1、NAT2、PSD3、NSAP11、LOC100128993、SH2D4A、CSGALNACT1、INTS10、LPL、SLC18A1、ATP6V1B2、LZTS1、LZTS1-AS1、LOC286114、GFRA2、DOK2、XPO7、NPM2、FGF17、EPB49、FAM160B2、NUDT18、HR、REEP4、LGI3、SFTPC、BMP1、PHYHIP、MIR320A、POLR3D、LOC100507071、PIWIL2、SLC39A14、PPP3CC、SORBS3、PDLIM2、C8orf58、KIAA1967、BIN3、FLJ14107、EGR3、PEBP4、RHOBTB2、TNFRSF10B、LOC286059、LOC254896、TNFRSF10C、TNFRSF10D、TNFRSF10A、LOC389641、CHMP7、R3HCC1、LOXL2、LOC100507156、ENTPD4、SLC25A37、NKX3-1、NKX2-6、STC1、ADAM28、ADAMDEC1、ADAM7、LOC100507207、NEFM、NEFL、DOCK5、GNRH1、KCTD9、CDCA2、LOC100507222、EBF2、PPP2R2A、BNIP3L、PNMA2、DPYSL2、ADRA1A、MIR548H4、STMN4、TRIM35、PTK2B、CHRNA2、EPHX2、CLU、SCARA3、MIR3622B、MIR3622A、CCDC25、ESCO2、PBK、SCARA5、MIR4287、NUGGC、ELP3、PNOC、ZNF395、FBXO16、FZD3、MIR4288、EXTL3、INTS9、HMBOX1、KIF13B、DUSP4、LINC00589、LOC286135、MIR3148、TMEM66、LEPROTL1、MBOAT4、DCTN6、LOC100128750、RBPMS、GTF2E2、LOC100507341、GSR、UBXN8、PPP2CB、TEX15、PURG、WRN、NRG1、NRG1-IT3、FUT10、MAK16、TTI2、SNORD13、RNF122、DUSP26、UNC5D、KCNU1、LOC100507403、LOC100507420、LOC100507439、ZNF703、ERLIN2、LOC728024、PROSC、GPR124、BRF2、RAB11FIP1、GOT1L1、ADRB3、EIF4EBP1、ASH2L、STAR、LSM1、BAG4、DDHD2、PPAPDC1B、WHSC1L1、LETM2、FGFR1、C8orf86、RNF5P1、TACC1、PLEKHA2、HTRA4、TM2D2、ADAM9、ADAM32、ADAM5、ADAM3A、LOC100130964、ADAM18、ADAM2、IDO1、IDO2、C8orf4、LOC100507481、LOC100996474、ZMAT4、SFRP1、MIR548AO、GOLGA7、GINS4、AGPAT6、NKX6-3、ANK1、MIR486、KAT6A、AP3M2、PLAT、IKBKB、POLB、DKK4、VDAC3、SLC20A2、C8orf40、CHRNB3、CHRNA6、THAP1、RNF170、MIR4469、HOOK3、FNTA、SGK196、HGSNAT、POTEA、LINC00293、LOC100505775、LOC100287846、KIAA0146、CEBPD、PRKDC、MCM4、UBE2V2、EFCAB1、SNAI2、C8orf22、LOC100507464、SNTG1、PXDNL、PCMTD1、LOC100287313、ST18、FAM150A、RB1CC1、NPBWR1、OPRK1、ATP6V1H、RGS20、TCEA1、LYPLA1、MRPL15、RNU105C、SOX17、LOC100129098、RP1、LOC100996304、LOC100287651、XKR4、SBF1P1、TMEM68、TGS1、LYN、RPS20、SNORD54、MOS、PLAG1、CHCHD7、SDR16C5、SDR16C6P、PENK、LOC100507632、IMPAD1、LOC100507651、LOC286177、LINC00588、LOC286178、FAM110B、UBXN2B、CYP7A1、SDCBP、NSMAF、TOX、LOC100505501、CA8、LOC100505532、RAB2A、CHD7、LOC100130298、CLVS1、ASPH、MIR4470、NKAIN3、UG0898H09、GGH、TTPA、YTHDF3、LOC286184、LOC100130155、
MIR124-2、LOC401463、BHLHE22、CYP7B1、LOC100505613、LINC00251、LOC286186、ARMC1、MTFR1、PDE7A、DNAJC5B、TRIM55、CRH、LOC100505659、LOC100505676、RRS1、ADHFE1、C8orf46、MYBL1、VCPIP1、C8orf44-SGK3、C8orf44、SGK3、PTTG3P、MCMDC2、SNHG6、SNORD87、TCF24、PPP1R42、COPS5、CSPP1、ARFGEF1、CPA6、PREX2、LOC286189、C8orf34、LOC100505718、LOC100505739、SULF1、SLCO5A1、PRDM14、NCOA2、TRAM1、LOC286190、LACTB2、XKR9、EYA1、MSC、LOC100132891、TRPA1、LOC392232、KCNB2、LOC100288310、TERF1、SBSPON、LOC100130301、RPL7、RDH10、STAU2-AS1、STAU2、UBE2W、TCEB1、TMEM70、LY96、JPH1、GDAP1、MIR5681A、MIR5681B、FLJ39080、MIR2052、PI15、CRISPLD1、HNF4G、ZFHX4-AS1、ZFHX4、PEX2、PKIA、ZC2HC1A、IL7、STMN2、HEY1、MRPS28、TPD52、MIR5708、ZBTB10、ZNF704、PAG1、FABP5、PMP2、FABP9、FABP4、FABP12、IMPA1、SLC10A5、ZFAND1、CHMP4C、SNX16、RALYL、LRRCC1、E2F5、C8orf59、LOC100507258、CA13、CA1、CA3、LOC100996348、CA2、REXO1L1、REXO1L2P、LOC100288562、PSKH2、ATP6V0D2、SLC7A13、WWP1、FAM82B、CPNE3、CNGB3、CNBD1、DCAF4L2、MMP16、LOC100996398、LOC100506342、RIPK2、OSGIN2、NBN、DECR1、CALB1、LINC00534、TMEM64、LOC100506351、NECAB1、LOC100127983、TMEM55A、LOC100506365、OTUD6B、LRRC69、MIR4661、SLC26A7、RUNX1T1、FLJ46284、TRIQK、C8orf87、LINC00535、FAM92A1、FP6628、RBM12B、RBM12B-AS1、TMEM67、MIR378D2、PDP1、CDH17、GEM、RAD54B、FSBP、KIAA1429、LOC100288748、ESRP1、DPY19L4、INTS8、CCNE2、TP53INP1、LOC100506538、NDUFAF6、LOC286149、MIR3150B、MIR3150A、PLEKHF2、C8orf69、C8orf37、LOC100616530、LOC100500773、GDF6、UQCRB、MTERFD1、PTDSS1、SDC2、CPQ、TSPYL5、MTDH、LAPTM4B、MATN2、LOC100506558、RPL30、SNORA72、C8orf47、HRSP12、POP1、NIPAL2、KCNS2、STK3、OSR2、VPS13B、MIR599、MIR875、COX6C、RGS22、MIR1273A、FBXO43、POLR2K、SPAG1、RNF19A、MIR4471、ANKRD46、SNX31、PABPC1、YWHAZ、FLJ42969、ZNF706、LOC100506652、NACAP1、GRHL2、NCALD、MIR5680、RRM2B、UBR5、ODF1、KLF10、AZIN1、LOC100506753、LOC100996457、ATP6V1C1、C8orf56、BAALC、MIR3151、LOC100499183、FZD6、CTHRC1、SLC25A32、DCAF13、LOC100996462、RIMS2、DCSTAMP、DPYS、LOC100130232、MIR548A3、LRP12、ZFPM2、OXR1、ABRA、ANGPT1、RSPO2、EIF3E、EMC2、TMEM74、TRHR、NUDCD1、ENY2、PKHD1L1、EBAG9、SYBU、KCNV1、CSMD3、MIR2053、TRPS1、LINC00536、EIF3H、UTP23、RAD21、RAD21-AS1、MIR3610、AARD、SLC30A8、MED30、EXT1、SAMD12、SAMD12-AS1、TNFRSF11B、COLEC10、MAL2、NOV、ENPP2、TAF2、DSCC1、DEPTOR、COL14A1、MRPL13、MTBP、SNTB1、HAS2、HAS2-AS1、ZHX2、DERL1、WDR67、FAM83A、LOC100131726、MIR4663、
C8orf76、ZHX1-C8ORF76、ZHX1、ATAD2、MIR548D1、MIR548AA1、WDYHV1、FBXO32、KLHL38、ANXA13、FAM91A1、FER1L6、FER1L6-AS1、TMEM65、TRMT12、LOC100507018、RNF139、TATDN1、NDUFB9、MTSS1、MIR4662B、MIR4662A、LOC157381、ZNF572、SQLE、KIAA0196、NSMCE2、TRIB1、LOC100130231、FAM84B、PCAT1、LOC100507056、POU5F1B、LOC727677、MYC、MIR1204、PVT1、LOC100507101、TMEM75、MIR1205、MIR1206、MIR1207、MIR1208、LOC728724、MIR3686、GSDMC、FAM49B、MIR5194、ASAP1、LOC100507117、ASAP1-IT1、ADCY8、EFR3A、OC90、HHLA1、KCNQ3、HPYR1、LRRC6、TMEM71、PHF20L1、TG、SLA、WISP1、NDRG1、ST3GAL1、LOC100507162、ZFAT、ZFAT-AS1、MIR30B、MIR30D、LOC286094、KHDRBS3、FLJ45872、FAM135B、COL22A1、KCNK9、TRAPPC9、LOC100131910、CHRAC1、EIF2C2、PTK2、MIR151A、DENND3、SLC45A4、LOC731779、GPR20、PTP4A3、FLJ43860、MIR1302-7、MIR4472-1、LINC00051、TSNARE1、BAI1、ARC、JRK、PSCA、LY6K、LOC100288181、THEM6、SLURP1、LYPD2、LYNX1、LY6D、GML、CYP11B1、CYP11B2、LOC100133669、LY6E、C8orf31、LY6H、GPIHBP1、ZFP41、GLI4、LOC100507316、ZNF696、TOP1MT、RHPN1-AS1、RHPN1、MAFA、ZC3H3、GSDMD、C8orf73、NAPRT1、EEF1D、TIGD5、PYCRL、TSTA3、ZNF623、ZNF707、BREA2、CCDC166、MAPK15、FAM83H、MIR4664、LOC100128338、SCRIB、MIR937、PUF60、NRBP2、EPPK1、PLEC、MIR661、PARP10、GRINA、SPATC1、SMPD5、OPLAH、EXOSC4、GPAA1、CYC1、SHARPIN、MAF1、KIAA1875、FAM203A、HEATR7A、SCXB、FAM203B、LOC377711、BOP1、SCXA、HSF1、DGAT1、SCRT1、TMEM249、FBXL6、SLC52A2、ADCK5、CPSF1、MIR939、MIR1234、SLC39A4、VPS28、TONSL、LOC100287098、CYHR1、KIFC2、FOXH1、PPP1R16A、GPT、MFSD3、RECQL4、LRRC14、LRRC24、C8orf82、ARHGAP39、LOC100996662、ZNF251、ZNF34、RPL8、ZNF517、LOC100129596、ZNF7、COMMD5、ZNF250、ZNF16、ZNF252P、TMED10P1、ZNF252P-AS1、C8orf33、DDX11L5、WASH1、MIR1302-9、FAM138C、FOXD4、CBWD1、C9orf66、DOCK8、KANK1、DMRT1、DMRT3、DMRT2、SMARCA2、FLJ35024、VLDLR、KCNV2、KIAA0020、RFX3、DSERG1、GLIS3、GLIS3-AS1、SLC1A1、SPATA6L、PPAPDC2、CDC37L1、AK3、RCL1、MIR101-2、JAK2、INSL6、INSL4、RLN2、RLN1、PLGRKT、CD274、PDCD1LG2、KIAA1432、ERMP1、MLANA、KIAA2026、MIR4665、RANBP6、LOC100506189、IL33、TPD52L3、UHRF2、C9orf38、GLDC、KDM4C、C9orf123、PTPRD、TYRP1、LURAP1L、MPDZ、FLJ41200、LOC100506304、LINC00583、NFIB、ZDHHC21、CER1、FREM1、LOC389705、TTC39B、SNAPC3、PSIP1、CCDC171、RNU6-14、LOC100506331、BNC2、LOC648570、CNTLN、SH3GL2、ADAMTSL1、MIR3152、FAM154A、RRAGA、HAUS6、SCARNA8、PLIN2、DENND4C、RPS6、ACER2、LOC392288、SLC24A2、MLLT3、MIR4473、MIR4474、FOCAD、MIR491、PTPLAD2、
IFNB1、IFNW1、IFNA21、IFNA4、IFNA7、IFNA10、IFNA16、IFNA17、IFNA14、IFNA22P、IFNA5、KLHL9、IFNA6、IFNA13、IFNA2、IFNA8、IFNA1、MIR31HG、IFNE、MIR31、MTAP、C9orf53、CDKN2A、CDKN2B-AS1、CDKN2B、DMRTA1、FLJ35282、ELAVL2、IZUMO3、TUSC1、LOC100506422、CAAP1、PLAA、IFT74、LRRC19、TEK、LINC00032、EQTN、MOB3B、IFNK、C9orf72、LINGO2、MIR876、MIR873、LOC401497、ACO1、DDX58、TOPORS、LOC100129250、NDUFB6、C9orf133、TAF1L、TMEM215、APTX、DNAJA1、SMU1、B4GALT1、SPINK4、BAG1、CHMP5、NFX1、AQP7、AQP3、NOL6、SUGT1P1、ANKRD18B、ANXA2P2、PTENP1、PRSS3、UBE2R2、UBAP2、SNORD121B、SNORD121A、DCAF12、UBAP1、KIF24、NUDT2、KIAA1161、C9orf24、FAM219A、DNAI1、ENHO、CNTFR、LOC415056、RPP25L、DCTN3、ARID3C、SIGMAR1、GALT、IL11RA、CCL27、LOC730098、CCL19、CCL21、FAM205A、FAM205B、KIAA1045、DNAJB5、C9orf131、VCP、FANCG、PIGO、STOML2、FAM214B、UNC13B、LOC100509263、ATP8B5P、RUSC2、FAM166B、TESK1、MIR4667、CD72、SIT1、RMRP、CCDC107、ARHGEF39、CA9、TPM2、TLN1、CREB3、GBA2、RGP1、MSMP、NPR2、SPAG8、HINT2、FAM221B、TMEM8B、FP588、OR13J1、HRCT1、LOC158376、OR2S2、RECK、GLIPR2、CCIN、CLTA、GNE、RNF38、MELK、MIR4475、PAX5、MIR4540、MIR4476、LOC100130458、LOC100506710、ZCCHC7、GRHPR、ZBTB5、POLR1E、FBXO10、TOMM5、FRMPD1、TRMT10B、EXOSC3、DCAF10、SLC25A51、SHB、ALDH1B1、IGFBPL1、FAM220BP、LOC100289137、ANKRD18A、FAM201A、CNTNAP3、SPATA31A1、LOC653501、SPATA31A2、FAM74A1、LOC441402、SPATA31A3、FAM74A3、ZNF658、FAM74A2、SPATA31A4、SPATA31A5、ZNF658B、MGC21881、KGFLP2、ANKRD20A2、FAM95B1、LOC100996667、CBWD7、FOXD4L2、LOC100996312、AQP7P3、ANKRD20A3、LOC642929、SPATA31A6、CNTNAP3B、LOC100505781、FAM27C、FAM27E4P、FAM27A、FAM27E2、LOC100287368、LOC100507284、FAM27E1、FAM27D1、LOC100996612、KGFLP1、LOC643648、LOC100126582、FAM74A4、SPATA31A7、LOC100996689、LOC100132249、PTGER4P2、LOC100132004、LOC286297、AQP7P1、LOC100996643、FAM27E3、FAM27B、LOC100132859、ANKRD20A1、MIR4477A、MIR4477B、LOC642236、LOC100132352、MIR1299、PGM5P2、LOC440896、FOXD4L6、CBWD6、ANKRD20A4、LOC100132154、LOC100996489、FOXD4L5、LOC100996547、FOXD4L4、CBWD5、CBWD3、FOXD4L3、PGM5-AS1、PGM5、TMEM252、PIP5K1B、FAM122A、LOC100996482、PRKACG、FXN、TJP2、BANCR、FAM189A2、APBA1、PTAR1、LOC494558、C9orf135、MAMDC2、LOC100507244、LOC100507299、SMC5、KLF9、TRPM3、MIR204、LOC100996487、TMEM2、FAM108B1、C9orf85、C9orf57、GDA、ZFAND5、TMC1、ALDH1A1、ANXA1、RORB、TRPM6、C9orf40、C9orf41、NMRK1、OSTF1、PCSK5、RFK、RPSAP9、GCNT1、PRUNE2、PCA3、FOXB2、VPS13A-AS1、VPS13A、
GNA14、GNAQ、CEP78、PSAT1、LOC100506414、TLE4、TLE1、SPATA31D5P、SPATA31D4、SPATA31D3、SPATA31D1、SPATA31B1、RASEF、FRMD3、IDNK、UBQLN1、GKAP1、KIF27、C9orf64、HNRNPK、MIR7-1、RMI1、SLC28A3、NTRK2、AGTPBP1、LOC389765、NAA35、GOLM1、C9orf153、ISCA1、ZCCHC6、GAS1、LOC100506834、LOC440173、LOC494127、C9orf170、DAPK1、CTSL1、CTSL3、CTSL1P8、LOC392364、LOC100506912、SPATA31E1、SPATA31C1、LOC100996508、CDK20、LOC100653206、SPATA31C2、SPIN1、NXNL2、LOC286238、MIR4289、C9orf47、S1PR3、SHC3、LOC100507009、CKS2、MIR3153、SECISBP2、SEMA4D、GADD45G、UNQ6494、LOC286370、MIR4290、LOC340515、DIRAS2、SYK、LOC100129316、LOC100507103、LOC100128909、FP2234、AUH、NFIL3、MIR3910-1、MIR3910-2、ROR2、SPTLC1、LOC100128076、LINC00475、IARS、MIR3651、SNORA84、NOL8、CENPP、OGN、OMD、ASPN、ECM2、MIR4670、IPPK、LOC100128361、BICD2、ANKRD19P、ZNF484、FGD3、SUSD3、C9orf89、NINJ1、WNK2、C9orf129、FAM120AOS、FAM120A、PHF2、MIR548AU、MIR4291、BARX1、PTPDC1、LOC100996250、MIRLET7A1、MIRLET7F1、MIRLET7DHG、MIRLET7D、ZNF169、FAM22F、LOC100132077、LOC728026、HIATL1、FBP2、FBP1、C9orf3、MIR2278、MIR23B、MIR27B、MIR3074、MIR24-1、FANCC、PTCH1、LOC100507346、LOC100506667、LINC00476、ERCC6L2、LINC00092、LOC158435、LOC158434、HSD17B3、SLC35D2、ZNF367、HABP4、CDC14B、LOC100507364、AAED1、LOC441455、ZNF510、ZNF782、LOC100132781、LOC441454、FAM22G、HIATL2、CTSL2、LOC340508、ANKRD18CP、LOC100499484-C9ORF174、LOC100499484、C9orf174、MIR1302-8、LOC286359、TDRD7、TMOD1、TSTD2、NCBP1、XPA、FOXE1、C9orf156、HEMGN、ANP32B、NANS、TRIM14、CORO2A、TBC1D2、GABBR2、ANKS6、GALNT12、COL15A1、TGFBR1、ALG2、SEC61B、LOC100996569、LOC100507438、NR4A3、LOC441461、STX17、ERP44、INVS、TEX10、LOC100507449、MSANTD3、MSANTD3-TMEFF1、TMEFF1、MURC、LPPR1、BAAT、MRPL50、ZNF189、ALDOB、TMEM246、RNF20、GRIN3A、PPP3R2、CYLC2、SMC2、LOC100996287、OR13F1、OR13C4、OR13C3、OR13C8、OR13C5、OR13C2、OR13C9、OR13D1、NIPSNAP3A、NIPSNAP3B、LOC286367、ABCA1、SLC44A1、FSD1L、FKTN、TAL2、TMEM38B、ZNF462、RAD23B、KLF4、ACTL7B、ACTL7A、IKBKAP、FAM206A、CTNNAL1、TMEM245、MIR32、FRRS1L、EPB41L4B、PTPN3、MIR3927、PALM2、PALM2-AKAP2、AKAP2、C9orf152、TXN、TXNDC8、SVEP1、MUSK、LPAR1、OR2K2、KIAA0368、ZNF483、PTGR1、LRRC37A5P、DNAJC25-GNG10、DNAJC25、GNG10、C9orf84、UGCG、MIR4668、SUSD1、PTBP3、HSDL2、C9orf147、KIAA1958、INIP、SNX30、SLC46A2、ZNF883、ZFP37、FAM225B、FAM225A、SLC31A2、FKBP15、SLC31A1、CDC26、PRPF4、RNF183、WDR31、BSPRY、HDHD3、ALAD、POLE3、C9orf43、RGS3、
ZNF618、AMBP、KIF12、COL27A1、MIR455、ORM1、ORM2、AKNA、DFNB31、ATP6V1G1、C9orf91、LOC100996601、LOC100505478、TNFSF15、TNFSF8、TNC、DEC1、LINC00474、PAPPA、ASTN2、LOC100128505、TRIM32、SNORA70C、TLR4、DBC1、MIR147A、CDK5RAP2、MEGF9、FBXW2、LOC100288842、PSMD5、LOC253039、PHF19、TRAF1、C5、CNTRL、RAB14、GSN、STOM、GGTA1P、DAB2IP、TTLL11、TTLL11-IT1、MIR4478、NDUFA8、MORN5、LHX6、RBM18、MRRF、PTGS1、OR1J1、OR1J2、OR1J4、OR1N1、OR1N2、OR1L8、OR1Q1、OR1B1、OR1L1、OR1L3、OR1L4、OR1L6、OR5C1、OR1K1、PDCL、RC3H2、SNORD90、ZBTB6、ZBTB26、RABGAP1、GPR21、MIR600HG、MIR600、STRBP、CRB2、DENND1A、MIR601、LOC100505588、LHX2、NEK6、PSMB7、LOC100129034、GPR144、NR5A1、NR6A1、MIR181A2HG、MIR181A2、MIR181B2、OLFML2A、WDR38、RPL35、ARPC5L、GOLGA1、SCAI、PPP6C、RABEPK、HSPA5、GAPVD1、MAPKAP1、LOC51145、PBX3、FAM125B、NRON、LMX1B、LOC100505986、ZBTB43、ZBTB34、RALGPS1、ANGPTL2、GARNL3、SLC2A8、ZNF79、RPL12、SNORA65、LRSAM1、FAM129B、STXBP1、MIR3911、C9orf117、PTRH1、TTC16、TOR2A、SH2D3C、MIR3960、MIR2861、CDK9、FPGS、ENG、AK1、MIR4672、ST6GALNAC6、ST6GALNAC4、PIP5KL1、DPM2、FAM102A、NAIF1、SLC25A25、LOC100289019、PTGES2、LOC389791、LCN2、C9orf16、CIZ1、DNM1、MIR199B、MIR3154、GOLGA2、SWI5、TRUB2、COQ4、SLC27A4、URM1、MIR219-2、MIR2964A、CERCAM、ODF2、GLE1、SPTAN1、WDR34、SET、PKN3、ZDHHC12、LOC100506100、ZER1、TBC1D13、ENDOG、C9orf114、CCBL1、LRRC8A、PHYHD1、DOLK、NUP188、SH3GLB2、FAM73B、DOLPP1、CRAT、PPP2R4、IER5L、C9orf106、LOC100506119、LOC100506190、LOC100128077、C9orf50、NTMT1、ASB6、PRRX2、PTGES、TOR1B、TOR1A、C9orf78、USP20、FNBP1、GPR107、FLJ46836、NCS1、HMCN2、ASS1、LOC100272217、FUBP3、PRDM12、EXOSC2、ABL1、QRFP、FIBCD1、LAMC3、AIF1L、NUP214、FAM78A、PPAPDC3、PRRC2B、SNORD62A、SNORD62B、POMT1、UCK1、RAPGEF1、MED27、NTNG2、SETX、TTF1、C9orf171、BARHL1、DDX31、GTF3C4、AK8、C9orf9、TSC1、MIR548AW、GFI1B、GTF3C5、LOC100996574、CEL、CELP、RALGDS、GBGT1、OBP2B、ABO、SURF6、MED22、RPL7A、SNORD24、SNORD36B、SNORD36A、SNORD36C、SURF1、SURF2、SURF4、C9orf96、REXO4、ADAMTS13、CACFD1、SLC2A6、TMEM8C、ADAMTSL2、FAM163B、DBH、DBH-AS1、SARDH、VAV2、LINC00094、BRD3、LOC100130548、WDR5、RNU6ATAC、RXRA、MIR4669、LOC100506532、COL5A1、MIR3689C、MIR3689A、MIR3689D1、MIR3689B、MIR3689D2、MIR3689E、MIR3689F、FCN2、FCN1、OLFM1、LOC401557、C9orf62、LOC100506599、PPP1R26、C9orf116、MRPS2、LCN1、OBP2A、PAEP、LOC100130954、GLT6D1、LCN9、SOHLH1、KCNT1、CAMSAP1、LOC100506620、UBAC1、NACC2、C9orf69、LOC100129999、RBSG2、LHX3、
QSOX2、ESP33、DKFZP434A062、GPSM1、DNLZ、CARD9、SNAPC4、SDCCAG3、PMPCA、INPP5E、SEC16A、C9orf163、NOTCH1、MIR4673、MIR4674、LOC401561、EGFL7、MIR126、AGPAT2、FAM69B、SNHG7、SNORA43、SNORA17、LCN10、LCN6、LOC100128593、LCN8、LCN15、TMEM141、KIAA1984、KIAA1984-AS1、RABL6、MIR4292、C9orf172、PHPT1、MAMDC4、EDF1、TRAF2、MIR4479、FBXW5、C8G、LCN12、PTGDS、LCNL1、C9orf142、CLIC3、ABCA2、C9orf139、FUT7、NPDC1、ENTPD2、SAPCD2、UAP1L1、LOC100289341、MAN1B1、DPP7、GRIN1、LRRC26、MIR3621、TMEM210、ANAPC2、SSNA1、TPRN、TMEM203、NDOR1、RNF208、LOC100130547、C9orf169、RNF224、SLC34A3、TUBB4B、FAM166A、LOC100129722、C9orf173、COBRA1、TOR4A、NRARP、EXD3、NOXA1、ENTPD8、NELF、PNPLA7、MRPL41、WDR85、ZMYND19、ARRDC1、C9orf37、EHMT1、FLJ40292、LOC651337、MIR602、LOC100133077、CACNA1B、TUBBP5、FAM157B、PLCXD1、GTPBP6、LINC00685、PPP2R3B、SHOX、CRLF2、CSF2RA、MIR3690、IL3RA、SLC25A6、ASMTL-AS1、ASMTL、P2RY8、AKAP17A、ASMT、DHRSX、ZBED1、CD99P1、LINC00102、CD99、XG、GYG2、ARSD、ARSE、ARSH、ARSF、CXorf28、MXRA5、PRKX、LOC389906、LOC441528、LOC100506453、LOC729162、NLGN4X、MIR4770、VCX3A、HDHD1、MIR4767、STS、VCX、PNPLA4、LOC100506502、MIR651、VCX2、VCX3B、KAL1、FAM9A、FAM9B、TBL1X、GPR143、SHROOM2、LOC100288814、WWC3、CLCN4、MID1、HCCS、ARHGAP6、AMELX、MIR548AX、MSL3、FRMPD4、PRPS2、TLR7、TLR8-AS1、TLR8、TMSB4X、FAM9C、LOC100093698、ATXN3L、LOC100133123、EGFL6、TCEANC、RAB9A、TRAPPC2、OFD1、GPM6B、GEMIN8、GLRA2、FANCB、MOSPD2、ASB9、ASB11、PIGA、PIR-FIGF、FIGF、PIR、BMX、ACE2、LOC100506630、TMEM27、CA5BP1、LOC100506661、CA5B、INE2、ZRSR2、AP1 S2、GRPR、MAGEB17、CTPS2、MIR548AM、S100G、SYAP1、TXLNG、RBBP7、REPS2、NHS、MIR4768、SCML1、RAI2、BEND2、SCML2、CDKL5、RS1、PPEF1、PHKA2-AS1、PHKA2、GPR64、PDHA1、MAP3K15、SH3KBP1、CXorf23、LOC729609、MAP7D2、MIR23C、EIF1AX、SCARNA9L、RPS6KA3、CNKSR2、KLHL34、SMPX、MBTPS2、YY2、SMS、PHEX、PHEX-AS1、LOC100873065、ZNF645、DDX53、PTCHD1、PRDX4、ACOT9、SAT1、APOO、CXorf58、KLHL15、EIF2S3、ZFX-AS1、ZFX、FAM48B2、FAM48B1、PDK3、PCYT1B、POLA1、SCARNA23、ARX、MAGEB18、MAGEB6、VENTXP1、SMEK3P、DCAF8L2、MAGEB10、DCAF8L1、IL1RAPL1、MIR4666B、MAGEB2、MAGEB3、MAGEB4、MAGEB1、NR0B1、CXorf21、GK、TAB3、FTHL17、DMD、MIR3915、MIR548F5、FAM47A、TMEM47、FAM47B、MAGEB16、CXorf22、CXorf59、CXorf30、FAM47C、PRRG1、LANCL3、XK、CYBB、DYNLT3、CXorf27、SYTL5、MIR548AJ2、SRPX、RPGR、OTC、TSPAN7、MID1IP1、LOC286442、MIR3937、MIR1587、LOC100506641、BCOR、ATP6AP2、MPC1L、CXorf38、MED14、
LOC100132831、USP9X、DDX3X、NYX、CASK、GPR34、GPR82、PPP1R2P9、MAOA、MAOB、NDP、EFHC2、FUNDC1、DUSP21、KDM6A、CXorf36、MIR221、MIR222、ZNF673、ZNF674、ZNF674-AS1、CHST7、SLC9A7、RP2、CXorf31、PHF16、RGN、NDUFB11、RBM10、UBA1、INE1、CDK16、USP11、ZNF157、SNORA11C、ZNF41、CXorf24、ARAF、SYN1、TIMP1、MIR4769、CFP、ELK1、UXT、LOC100133957、CXXC1P1、LOC441493、ZNF81、ZNF182、SPACA5、ZNF630、SSX6、SPACA5B、SSX5、SSX1、SSX3、SSX4、SSX4B、SLC38A5、FTSJ1、PORCN、EBP、TBC1D25、RBM3、WDR13、WAS、SUV39H1、GLOD5、GATA1、HDAC6、ERAS、PCSK1N、TIMM17B、PQBP1、SLC35A2、PIM2、OTUD5、KCND1、GRIPAP1、TFE3、CCDC120、PRAF2、WDR45、GPKOW、MAGIX、PLP2、PRICKLE3、SYP、CACNA1F、CCDC22、FOXP3、PPP1R3F、GAGE10、GAGE12J、GAGE13、GAGE2E、GAGE2D、GAGE12I、GAGE2C、GAGE2B、GAGE12C、GAGE12D、GAGE12E、GAGE12F、GAGE12G、GAGE12H、GAGE2A、GAGE1、PAGE1、PAGE4、LOC158572、USP27X、CLCN5、MIR532、MIR188、MIR500A、MIR362、MIR501、MIR500B、MIR660、MIR502、AKAP4、CCNB3、DGKK、SHROOM4、BMP15、NUDT10、CXorf67、NUDT11、CENPVP2、CENPVP1、GSPT2、MAGED1、MAGED4B、SNORA11E、MAGED4、SNORA11D、LOC100129860、XAGE2、XAGE1B、XAGE1A、XAGE1C、XAGE1D、XAGE1E、SSX8、SSX7、SSX2、SSX2B、SPANXN5、XAGE5、XAGE3、FAM156B、FAM156A、GPR173、TSPYL2、KDM5C、IQSEC2、SMC1A、RIBC1、HSD17B10、HUWE1、MIR98、MIRLET7F2、PHF8、FAM120C、WNK3、TSR2、FGD1、GNL3L、ITIH6、MAGED2、SNORA11、TRO、PFKFB1、APEX2、ALAS2、PAGE2B、PAGE2、FAM104B、MTRNR2L10、PAGE5、PAGE3、MIR4536-1、MAGEH1、USP51、FOXR2、XAGE-4、RRAGB、KLF8、UBQLN2、LOC550643、UQCRBP1、SPIN3、SPIN2B、SPIN2A、FAAH2、ZXDB、ZXDA、SPIN4、LOC92249、ARHGEF9、MIR1468、FAM123B、ASB12、MTMR8、ZC4H2、ZC3H12B、LAS1L、FRMD8P1、MSN、MIR223、VSIG4、HEPH、EDA2R、AR、OPHN1、YIPF6、STARD8、EFNB1、PJA1、LOC100996279、FAM155B、EDA、MIR676、AWAT2、OTUD6A、IGBP1、DGAT2L6、AWAT1、P2RY4、ARR3、RAB41、PDZD11、KIF4A、GDPD2、DLG3、TEX11、SLC7A3、SNX12、FOXO4、CXorf65、IL2RG、MED12、NLGN3、GJB1、ZMYM3、NONO、ITGB1BP2、TAF1、INGX、OGT、ACRC、CXCR3、LOC100129291、FLJ46446、CXorf49、CXorf49B、LOC100132741、NHSL2、RPS26P11、RGAG4、FLJ44635、PIN4、ERCC6L、RPS4X、CITED1、HDAC8、PHKA1、FAM226B、LOC100132304、DMRTC1B、DMRTC1、LINC00684、FAM226A、PABPC1L2B、PABPC1L2A、NAP1L6、NAP1L2、CDX4、MAP2K4P1、CHIC1、TSIX、XIST、JPX、FTX、LOC100506745、MIR421、MIR374B、MIR374C、MIR545、MIR374A、ZCCHC13、SLC16A2、RLIM、KIAA2022、ABCB7、UPRT、ZDHHC15、TTC3P1、MAGEE2、CXorf26、MAGEE1、MIR384、MIR325、FGF16、ATRX、MAGT1、COX7B、ATP7A、PGAM4、PGK1、
TAF9B、CYSLTR1、ZCCHC5、LPAR4、MIR4328、P2RY10、GPR174、ITM2A、TBX22、FAM46D、BRWD3、HMGN5、SH3BGRL、POU3F4、CYLC1、RPS6KA6、MIR548I4、HDX、UBE2DNL、APOOL、SATL1、ZNF711、POF1B、MIR1321、CHM、MIR361、DACH2、KLHL4、CPXCR1、TGIF2LX、PABPC5、PCDH11X、NAP1L3、FAM133A、MIR548M、LOC643486、DIAPH2、RPA4、LOC442459、PCDH19、TNMD、TSPAN6、SRPX2、SYTL4、CSTF2、NOX1、XKRX、ARL13A、TRMT2B、TMEM35、CENPI、DRP2、TAF7L、TIMM8A、BTK、RPL36A-HNRNPH2、RPL36A、GLA、HNRNPH2、ARMCX4、ARMCX1、ARMCX6、ARMCX3-AS1、ARMCX3、RNU6-30、ARMCX2、NXF5、ZMAT1、TCEAL2、TCEAL6、BEX5、LOC100996631、NXF2、NXF2B、LOC100996648、TMSB15A、NXF4、ARMCX5、ARMCX5-GPRASP2、GPRASP1、GPRASP2、BHLHB9、LINC00630、RAB40AL、BEX1、NXF3、BEX4、TCEAL8、TCEAL5、BEX2、TCEAL7、WBP5、NGFRAP1、LOC100506901、RAB40A、TCEAL4、TCEAL3、TCEAL1、MORF4L2、MORF4L2-AS1、GLRA4、TMEM31、PLP1、RAB9B、TMSB15B、H2BFXP、H2BFWT、H2BFM、SLC25A53、ZCCHC18、LOC286437、FAM199X、ESX1、IL1RAPL2、TEX13A、NRK、SERPINA7、MUM1L1、CXorf57、MIR548AN、RNF128、TBC1D8B、RIPPLY1、CLDN2、MORC4、RBM41、NUP62CL、PIH1D3、FRMPD3、PRPS1、TSC22D3、MID2、TEX13B、VSIG1、PSMD10、ATG4A、COL4A6、COL4A5、IRS4、GUCY2F、NXT2、KCNE1L、ACSL4、TMEM164、MIR652、MIR3978、AMMECR1、SNORD96B、RGAG1、TDGF1P3、CHRDL1、PAK3、CAPN6、DCX、DKFZp686D0853、ALG13、TRPC5、TRPC5OS、ZCCHC16、LHFPL1、AMOT、MIR4329、HTR2C、SNORA35、MIR764、MIR1912、MIR1264、MIR1298、MIR1911、MIR448、IL13RA2、LRCH2、RBMXL3、LUZP4、PLS3、AGTR2、SLC6A14、CXorf61、LOC100126447、KLHL13、WDR44、MIR1277、DOCK11、IL13RA1、ZCCHC12、LONRF3、KIAA1210、PGRMC1、SLC25A43、SLC25A5-AS1、SLC25A5、CXorf56、UBE2A、NKRF、SEPT6、MIR766、SOWAHD、RPL39、SNORA69、UPF3B、RNF113A、NDUFA1、AKAP14、NKAP、RHOXF2B、RHOXF1、RHOXF2、NKAPP1、ZBTB33、FAM70A、ATP1B4、LAMP2、CUL4B、MCTS1、C1GALT1C1、CT47B1、CT47A12、CT47A11、CT47A10、CT47A9、CT47A8、CT47A7、CT47A6、CT47A5、CT47A4、CT47A3、CT47A2、CT47A1、GLUD2、MIR3672、GRIA3、THOC2、XIAP、STAG2、SH2D1A、TENM1、LOC100129520、DCAF12L2、DCAF12L1、CXorf64、ACTRT1、SMARCA1、OCRL、APLN、XPNPEP2、SASH3、ZDHHC9、UTP14A、BCORL1、ELF4、AIFM1、RAB33A、ZNF280C、SLC25A14、GPR119、RBMX2、FAM45B、ENOX2、ARHGAP36、IGSF1、OR13H1、LOC286467、MST4、FRMD7、RAP2C、MBNL3、HS6ST2、HS6ST2-AS1、USP26、TFDP3、GPC4、GPC3、MIR363、MIR92A2、MIR19B2、MIR20B、MIR18B、MIR106A、CCDC160、PHF6、HPRT1、MIR450B、MIR450A1、MIR450A2、MIR542、MGC16121、MIR503、MIR424、LINC00629、PLAC1、FAM122B、FAM122C、MOSPD1、CXorf69、FAM127C、FAM127A、FAM127B、LINC00087、
LINC00633、LOC100287728、CXorf48、ZNF75D、ZNF449、LOC100506790、LINC00086、DDX26B、CT45A1、CT45A2、CT45A3、CT45A4、CT45A5、CT45A6、SAGE1、MMGT1、SLC9A6、FHL1、MAP7D3、GPR112、BRS3、HTATSF1、VGLL1、MIR934、LOC100128420、CD40LG、ARHGEF6、RBMX、SNORD61、GPR101、LOC100996525、ZIC3、LOC158696、FGF13、MIR504、FGF13-AS1、SRD5A1P1、F9、MCF2、ATP11C、MIR505、CXorf66、LOC389895、SOX3、RP1-177G6.2、CDR1、MIR320D2、SPANXB2、SPANXB1、LDOC1、SPANXC、SPANXA2-OT1、SPANXA1、SPANXA2、LOC645188、SPANXD、MAGEC3、MAGEC1、MAGEC2、SPANXN4、SPANXN3、SLITRK4、SPANXN2、UBE2NL、SPANXN1、SLITRK2、CXorf1、MIR890、MIR888、MIR892A、MIR892B、MIR891B、MIR891A、CXorf51B、CXorf51A、MIR513C、MIR513B、MIR513A1、MIR513A2、MIR506、MIR507、MIR508、MIR514B、MIR509-2、MIR509-3、MIR509-1、MIR510、MIR514A1、MIR514A2、MIR514A3、FMR1-AS1、FMR1、FMR1NB、AFF2、IDS、LOC100131434、CXorf40A、MAGEA9B、HSFX2、TMEM185A、MAGEA11、HSFX1、MAGEA9、MAGEA8、CXorf40B、LOC100272228、MIR2114、MAMLD1、MTM1、MTMR1、CD99L2、HMGB3、MIR4330、GPR50、VMA21、PASD1、PRRG3、FATE1、CNGA2、LOC100507199、MAGEA4、GABRE、MIR224、MIR452、MAGEA5、MAGEA10-MAGEA5、MAGEA10、GABRA3、MIR105-1、MIR767、MIR105-2、GABRQ、MAGEA6、CSAG3、MAGEA2B、MAGEA12、CSAG1、MAGEA2、CSAG2、MAGEA3、CETN2、NSDHL、ZNF185、PNMA5、PNMA3、PNMA6C、PNMA6D、PNMA6A、PNMA6B、MAGEA1、ZNF275、LOC649238、ZFP92、TREX2、HAUS7、BGN、ATP2B3、FAM58A、DUSP9、PNCK、SLC6A8、BCAP31、ABCD1、PLXNB3、SRPK3、IDH3G、SSR4、PDZD4、L1CAM、LOC100996465、AVPR2、ARHGAP4、NAA10、RENBP、HCFC1、TMEM187、MIR3202-1、MIR3202-2、IRAK1、MIR718、MECP2、OPN1LW、OPN1MW、OPN1MW2、TEX28、TKTL1、FLNA、EMD、RPL10、SNORA70、DNASE1L1、TAZ、ATP6AP1、GDI1、FAM50A、PLXNA3、LAGE3、UBL4A、SLC10A3、FAM3A、G6PD、IKBKG、FAM223A、CTAG1A、CTAG1B、FAM223B、CTAG2、GAB3、DKC1、SNORA36A、MIR644B、SNORA56、MPP1、CXorf68、F8、H2AFB1、F8A1、MIR1184-1、FUNDC2、CMC4、MTCP1、BRCC3、VBP1、RAB39B、CLIC2、H2AFB2、F8A2、MIR1184-2、F8A3、MIR1184-3、H2AFB3、TMLHE-AS1、TMLHE、SPRY3、VAMP7、IL9R、XGPY2、SRY、RPS4Y1、ZFY、LINC00278、TGIF2LY、PCDH11Y、TTTY23B、TSPY2、FAM197Y9、TTTY1B、TTTY2B、TTTY21B、TTTY7、TTTY8B、AMELY、TBL1Y、PRKY、TTTY16、TTTY12、TTTY18、TTTY19、TTTY11、RBMY1A3P、TTTY20、TSPY4、FAM197Y8、TSPY8、FAM197Y7、FAM197Y6、TSPY3、FAM197Y5、TSPY1、FAM197Y4、FAM197Y3、FAM197Y2、TSPY10、FAM197Y1、RBMY3AP、TTTY8、TTTY7B、TTTY21、TTTY2、TTTY1、TTTY22、TTTY23、GYG2P1、TTTY15、USP9Y、DDX3Y、UTY、TMSB4Y、VCY、VCY1B、NLGN4Y、NLGN4Y-AS1、
FAM41AY1、FAM224B、XKRY、CDY2B、CDY2A、XKRY2、FAM224A、FAM41AY2、HSFY1、TTTY9B、TTTY9A、HSFY2、NCRNA00185、TTTY14、BCORP1、TXLNG2P、KDM5D、TTTY10、EIF1AY、RPS4Y2、CYorf17、RBMY2EP、RBMY1B、RBMY1A1、TTTY13、RBMY1D、RBMY1E、PRY2、TTTY6B、RBMY1F、TTTY5、RBMY2FP、RBMY1J、TTTY6、PRY、TTTY17A、TTTY4、BPY2、DAZ1、DAZ2、TTTY3B、CDY1B、GOLGA2P2Y、TTTY17B、TTTY4B、BPY2B、DAZ3、DAZ4、BPY2C、TTTY4C、TTTY17C、GOLGA2P3Y、CSPG4P1Y、CDY1、TTTY3。

Claims (15)

1. A method of quality management of cells for therapeutic or drug development, the method comprising:
a step of managing the behavior of one or more specific protein molecules necessary for the manifestation of a cell-based therapeutic effect, and
a step of managing the expression behaviour of the relevant genome characteristic of said cell.
2. The method of claim 1, wherein,
the relevant genome characteristic of the cell consists of 10 to 2000 genes.
3. The method according to claim 1 or 2, wherein,
the related genome characteristic of the cell is selected from at least 1 or more of an immune-related genome, an inflammation-related genome, a angiogenesis-related genome, a nerve regeneration-related genome, a cartilage formation-related genome, a bone formation-related genome, an adipogenesis-related genome, a fibrosis-related genome, an immunogenicity-related genome, a migration-related genome, an adhesion-related genome, an aging-related genome, a mesenchymal stem cell marker-related genome, a surface marker-related genome, a growth factor-related genome, and a chemokine or cytokine-related genome.
4. A method according to any one of claim 1 to 3, wherein,
when the expression behavior of the related genome characteristic of the cell is managed, it is determined that the cell is usable when the correlation between the expression pattern of the genome obtained by measuring the expression state of the related genome characteristic of the cell and the expression pattern as a reference is a certain degree or more.
5. The method of claim 4, wherein,
the case where the correlation is a certain degree or more is a case where a correlation coefficient or a decision coefficient, or a correlation coefficient and a decision coefficient are evaluated and the correlation coefficient or the decision coefficient is a certain degree or more.
6. The method of claim 5, wherein,
in the case of evaluating the correlation coefficient or the decision coefficient, the correlation coefficient or the decision coefficient is calculated by performing any one of the following:
(i) The measurement lower limit value is used to replace the defect value of the expression quantity of the non-measurable gene,
(ii) Replacing defective value of the expression level of the gene which cannot be measured with the lowest value among the measured values, or
(iii) The following formula is used: the read count + (1×average gene length/gene length) of each gene was treated with a defect value at which the expression level of the gene could not be measured.
7. The method according to any one of claims 1 to 6, wherein,
the specific protein molecule is a cell surface antigen.
8. The method according to any one of claims 1 to 7, wherein,
the specific protein molecule comprises one or more of CD29 and CD140 b.
9. The method according to any one of claims 1 to 8, wherein,
The behavior of the specific protein molecule is the expression level.
10. The method according to any one of claims 1 to 9, wherein,
the cells are at least one cell selected from the group consisting of adult stem cells, induced pluripotent stem cells, embryonic stem cells, differentiated cells derived from adult stem cells, differentiated cells derived from induced pluripotent stem cells, and differentiated cells derived from embryonic stem cells.
11. The method according to any one of claims 1 to 10, wherein,
the cells are mesenchymal stem cells.
12. The method according to any one of claims 1 to 11, wherein,
the cells are cells useful as therapeutic agents for arthrosis.
13. The method according to any one of claims 1 to 12, wherein,
the cells are cells useful as a meniscus therapeutic agent or an osteoarthritis therapeutic agent.
14. The method according to any one of claims 1 to 11, wherein,
the cells are cells for drug development.
15. A method of making a cell for therapeutic or drug development, comprising:
a step of obtaining a candidate cell population comprising cells for therapeutic or drug development; and
A step of screening the cell population for cells satisfying a benchmark by the method of any one of claims 1 to 14.
CN202280049814.7A 2021-07-15 2022-02-10 Method for managing cell quality and method for producing cell Pending CN117730164A (en)

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