CN117122353B - Bone marrow stem cell draws with puncture sampling device - Google Patents

Bone marrow stem cell draws with puncture sampling device Download PDF

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Publication number
CN117122353B
CN117122353B CN202311401225.3A CN202311401225A CN117122353B CN 117122353 B CN117122353 B CN 117122353B CN 202311401225 A CN202311401225 A CN 202311401225A CN 117122353 B CN117122353 B CN 117122353B
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drill rod
middle drill
groove
needle core
hole
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CN117122353A (en
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巩赞华
巩赞斌
巩赞博
彭劼
张金银
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Shenzhen Pandao Biotechnology Co ltd
Huachenyang Shenzhen Technology Co ltd
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Shenzhen Pandao Biotechnology Co ltd
Huachenyang Shenzhen Technology Co ltd
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Publication of CN117122353A publication Critical patent/CN117122353A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/025Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/16Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
    • A61B17/1613Component parts
    • A61B17/1622Drill handpieces
    • A61B17/1624Drive mechanisms therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/16Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
    • A61B17/1662Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans for particular parts of the body
    • A61B17/1671Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans for particular parts of the body for the spine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3472Trocars; Puncturing needles for bones, e.g. intraosseus injections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0208Biopsy devices with actuators, e.g. with triggered spring mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/025Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
    • A61B2010/0258Marrow samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • A61B2017/3405Needle locating or guiding means using mechanical guide means
    • A61B2017/3409Needle locating or guiding means using mechanical guide means including needle or instrument drives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention relates to the field of bone marrow puncture, and discloses a puncture sampling device for bone marrow stem cell extraction, which comprises an outer shell, a puncture needle set and a driving source, wherein the puncture needle set comprises an outer needle sleeve arranged at the bottom of the outer shell, a middle drill rod is arranged in the hollow and sleeved mode in the outer needle sleeve, an inner needle core is arranged in the hollow and sleeved mode in the middle drill rod, the surface of the middle drill rod is smooth, the end part of the middle drill rod is provided with a cutter groove I, one end of the inner needle core is opened and extends out of the middle drill rod, the other end of the inner needle core is closed and is flush with the end part of the cutter groove I, the end of the inner needle core is provided with a cutter groove II, the cutter groove II is communicated with the cutter groove I, the inner wall of the middle drill rod is provided with a thread groove I, one end of the thread groove I is communicated with the cutter groove II, a communicating point is positioned at the communicating position of the cutter groove I, the outer circle surface of the inner needle core is provided with a drawing hole, the outer hole of the drawing hole is plugged by the inner wall of the middle drill rod, and bone meal generated in the drilling process is in the thread groove I under the matching traction of the inclined groove wall of the cutter groove I of the cutter groove II.

Description

Bone marrow stem cell draws with puncture sampling device
Technical Field
The invention relates to the field of medical equipment, in particular to the field of bone marrow puncture, and particularly relates to a puncture sampling device for bone marrow stem cell extraction.
Background
Bone marrow aspiration is a common diagnostic technique for collecting bone marrow fluid, which generally utilizes a bone marrow aspiration needle to collect bone marrow samples, the bone marrow aspiration needle is inserted into human bones, a needle core in the aspiration needle is withdrawn, and then an injector is connected to extract bone marrow, in the process, the aspiration needle can generate bone powder, bone dust and the like when being inserted into the human bones, the bone powder and the bone dust easily enter the aspiration needle to cause the blockage of the aspiration needle and influence the bone marrow extraction, and the Chinese patent application with the publication number of CN108309364B is found through retrieval to disclose a bone marrow aspiration device, which utilizes the cooperation of a hollow bone rod, a hexagonal prism and the like to solve the problems that the aspiration needle caused by the structural defect of the traditional aspiration needle is easy to be blocked by the bone powder and the pain of a patient is increased, however, the bone marrow aspiration device has some defects: referring to the steps of the bone marrow puncturing method disclosed in the patent, the preparation can be completed only through the steps 5-7, then the step 8 (namely, the hollow bone rod is drilled into the human skeleton) can be performed, in the steps 5-7, the fixed barrel is required to be repeatedly disassembled and assembled, the loose core is required to be pumped and rotated by 180 degrees, the action is complicated, and the whole puncturing process is manually operated, so that on one hand, the pain of a patient is increased due to shaking of a puncturing needle, and on the other hand, the time spent by the whole bone marrow puncturing is increased, and the pain of the patient is increased.
Based on the above, the invention provides a puncture sampling device for bone marrow stem cell extraction.
Disclosure of Invention
In order to solve the problems mentioned in the background, the invention provides a puncture sampling device for bone marrow stem cell extraction.
In order to achieve the technical purpose, the technical scheme adopted by the invention is as follows.
The puncture sampling device for bone marrow stem cell extraction comprises an outer shell, a puncture needle set and a driving source, wherein the puncture needle set and the driving source are arranged on the outer shell, the puncture needle set comprises an outer needle sleeve vertically arranged at the bottom of the outer shell, a middle drill rod is sleeved in the inner hollow part of the outer needle sleeve, and an inner needle core is sleeved in the inner hollow part of the middle drill rod;
the surface of the middle drill rod is smooth, the end part of the middle drill rod is provided with a cutter groove I, the cutter groove I is obliquely arranged along the groove wall of the middle drill rod in the circumferential direction, when the middle drill rod performs drilling action, bone meal generated by drilling is pulled towards the axial lead of the middle drill rod by the oblique groove wall of the cutter groove I, one end of the inner needle core is opened and extends out of the middle drill rod, a suction pipe is arranged at the tail end of the suction pipe through a rotary joint, the other end of the inner needle core is closed and is flush with the end part of the middle drill rod, which is provided with the cutter groove I, the end of the inner needle core is provided with a cutter groove II, the cutter groove II is communicated with the cutter groove I, the cutter groove II is obliquely arranged along the groove wall of the inner needle core in the circumferential direction, and when the inner needle core rotates along with the drilling action, the bone meal generated by drilling is pulled away from the axial lead of the inner needle core by the oblique groove wall of the cutter groove II;
the inner wall of the middle drill rod is provided with a first thread groove, one end of the first thread groove is communicated with the knife groove, a communication point is located at the communication position of the first knife groove and the second knife groove, the outer circular surface of the inner needle core is provided with a drawing hole penetrating through the wall thickness, and the drawing hole is close to the closed end of the inner needle core and the outer hole of the drawing hole is plugged by the inner wall of the middle drill rod.
Further, the inner wall of the middle drill rod is provided with a thread groove II, the outer circular surface of the inner needle core is provided with a ball pin, the ball pin is located in the thread groove II, and when the middle drill rod rotates in a drilling mode, the thread groove II and the ball pin are matched to enable the inner needle core to move upwards.
Further, the pitch of the second thread groove is the same as the pitch of the first thread groove.
Further, the inside of the outer shell is provided with an inner frame, the driving source comprises a driving mechanism and a limiting member, the driving mechanism is arranged on the inner frame and used for driving the puncture needle group to perform bone marrow puncture action in a single power source mode, and the limiting member is used for limiting the depth of the drilling action.
Further, the limiting component comprises a second screw rod arranged on the inner frame, the second screw rod is parallel to the outer needle sleeve, and the input end of the second screw rod extends out of the outer shell and is provided with a knob;
a limiting bracket is arranged on the second screw rod and is matched with the inner frame in a sliding guide way along the axial direction of the second screw rod;
the surface of shell body is provided with the sign hole, and one side in sign hole is provided with the scale mark, extends on the spacing support has the sign board, and the end of sign board is located the sign downthehole.
Further, an outer shaft shoulder is arranged outside the inner needle core, an inner shaft shoulder is arranged on the inner wall of the middle drill rod, and the upper end face of the outer shaft shoulder is contacted with the lower end face of the inner shaft shoulder in the initial stage.
Further, the driving mechanism comprises a motor and a differential mechanism, a first lead screw parallel to a second lead screw and a driving straight gear are arranged on the inner frame, an input shaft of the differential mechanism is in power connection with the motor, a first output half shaft of the differential mechanism is in power connection with the first lead screw, the second output half shaft of the differential mechanism is in power connection with the driving straight gear, a driven straight gear meshed with the driving straight gear is arranged outside the middle drill rod, and the driving straight gear is meshed with the driven straight gear when the middle drill rod moves together with the driven straight gear;
the external mounting of lead screw one has the linking bridge, and linking bridge and inner frame become along the axial slip direction cooperation of lead screw one, connect through the bearing between linking bridge and the inner needle core, connect through coupling assembling between linking bridge and the well drilling rod.
Further, the connecting component comprises an outer sleeve column which is axially and slidably arranged on the inner frame along the first screw rod, an inner sliding column is slidably arranged in the outer sleeve column, a first spring is arranged between the inner sliding column and the outer sleeve column, and the bottom of the inner sliding column is positioned between the outer sleeve column and the limiting support;
the inner part of the outer sleeve column is also provided with limiting blocks in a sliding manner along the horizontal direction, two groups of limiting blocks are arranged along the sliding direction, a second spring is arranged between the two groups of limiting blocks, the opposite side surfaces of the two groups of limiting blocks extend out of the outer sleeve column and consist of an upper plane and a lower inclined plane, the upper plane is parallel to the outer sleeve column, and the distance between the lower inclined planes of the two groups of limiting blocks is increased from bottom to top;
the bottom of stopper is provided with the end inclined plane, and the end inclined plane is located outside the sleeve post inside, and the distance between the end inclined plane of two sets of stopper increases gradually from bottom to top, and the top of interior slip post is provided with the top inclined plane, and top inclined plane and end inclined plane laminating.
Further, a first sleeve hole is formed in the connecting support, the outer sleeve column is sleeved in the first sleeve hole, and initially, the lower orifice of the first sleeve hole is contacted with the upper end face of the limiting block;
the limiting bracket is provided with a second sleeve hole which coaxially surrounds the periphery of the middle drill rod, the upper end surface of the limiting bracket extends to form a convex pin, the bottom of the driven straight gear is provided with a pin hole, and the pin hole is coaxially positioned above the convex pin;
the bottom of the outer sleeve column is extended to form a convex frame, a sleeve hole III is formed in the convex frame, a middle drill rod is movably sleeved in the sleeve hole III, a clamping ring is arranged outside the middle drill rod, the lower end face of the clamping ring is contacted with the upper orifice of the sleeve hole III, and a spring III is arranged between the lower orifice of the sleeve hole III and the upper end face of the driven spur gear.
Further, the bottom of the convex frame is provided with a pawl assembly, the pawl assembly and the driven straight gear jointly form a ratchet pawl structure, and the ratchet pawl structure is used for enabling the driven straight gear to only rotate through drilling.
Compared with the prior art, the invention has the beneficial effects that:
in the scheme, in the process of bone marrow puncture, in the use process of the puncture needle set, except that the outer needle sleeve is penetrated into the skin of a patient and is contacted with bones, other automatic operation is realized, and medical staff only need to hold the handle stably, so that the puncture sampling device does not shake and deviate, and pain suffered by the patient during bone marrow puncture is greatly reduced;
more importantly, bone meal generated by drilling is finally collected in the first thread groove, and in the processes of extending the bone drill and the inner needle core into the bone and retracting the drill rod in the inner needle core, the extraction holes for bone marrow extraction on the inner needle core are not contacted with the thread groove, namely, the bone meal, so that the non-blockage sampling is realized;
comprehensively, the non-blocking sampling action is simplified and automated, so that the problems that' repeated disassembly and assembly of a fixed cylinder is needed, pulling of a core is needed, and 180-degree rotation is needed, the action is very complicated, and the whole puncturing process is manually operated, so that on one hand, the puncturing needle is easy to shake to cause pain aggravation of a patient, and on the other hand, the time spent on the whole bone marrow puncturing is increased, and the pain of the patient is aggravated are solved;
on the basis of the above, the driving source drives the drill rod and the inner needle core to synchronously move in a feeding way (refer to a motor) by a single power source, the drill rod is driven to rotate in a drilling way, and the inner needle core is driven to move independently.
Drawings
FIG. 1 is an initial schematic of the present invention;
FIG. 2 is a schematic illustration of the present invention with the center drill rod and inner core extended;
FIG. 3 is a schematic view of the inner housing, drive source, and lancet assembly;
FIG. 4 is a cross-sectional view of the lancet assembly;
FIG. 5 is a schematic illustration of the partial mating of the center drill rod with the inner core;
FIG. 6 is a schematic diagram showing the partial cooperation of the middle drill rod and the inner core;
FIG. 7 is a schematic view of a retaining member;
FIG. 8 is a schematic view of the drive mechanism, the middle drill rod, and the inner core;
FIG. 9 is a schematic view of a connection bracket and connection assembly;
FIG. 10 is an internal schematic view of the connection assembly;
fig. 11 is a schematic view of a pawl assembly and driven spur gear.
The reference numerals in the drawings are:
100. an outer housing; 101. scale marks; 102. an inner frame; 200. a puncture needle set; 201. an outer needle sheath; 2021. a first thread groove; 2022. a thread groove II; 202. a middle drill rod; 203. an inner needle core; 2031. drawing holes; 204. ball pins; 205. drawing out a pipe; 206. a suction pump; 300. a driving mechanism; 301. a motor; 302. a differential; 303. a driving spur gear; 304. a first screw rod; 305. a driven spur gear; 306. a connecting bracket; 307. a connection assembly; 3071. an outer sleeve column; 3072. a convex frame; 3073. an inner slide; 3074. a first spring; 3075. a limiting block; 3076. a second spring; 308. a pawl assembly; 3081. a pawl; 3082. a coil spring; 309. a third spring; 400. a limiting member; 401. a knob; 402. a second screw rod; 403. a limit bracket; 404. a sign board; 405. and (5) a protruding pin.
Detailed Description
In order to further describe the technical means and effects adopted by the present invention for achieving the intended purpose, the following detailed description will refer to the specific implementation, structure, characteristics and effects according to the present invention with reference to the accompanying drawings and preferred embodiments.
Example 1
Referring to fig. 1 to 6, a puncture sampling device for bone marrow stem cell extraction includes an outer housing 100 for performing automated bone marrow puncture sampling on a patient, a puncture needle set 200 provided on the outer housing 100 for powering the operation thereof, and a driving source.
For ease of description, the lancet assembly 200 is illustrated with the entire vertical arrangement:
referring to fig. 2 and 4-6, the puncture needle set 200 includes an outer needle sheath 201 vertically disposed at the bottom of the outer housing 100, a middle drill rod 202 is sleeved in the outer needle sheath 201, and an inner needle core 203 is sleeved in the middle drill rod 202.
The surface of the middle drill rod 202 is smooth, the end part of the middle drill rod 202 is provided with a cutter groove I, the cutter groove I is obliquely arranged along the groove wall of the middle drill rod 202 in the circumferential direction, when the middle drill rod 202 performs drilling action, bone meal generated by drilling is pulled towards the axial lead of the middle drill rod 202 by the oblique groove wall of the cutter groove I, the cutter groove I penetrates through the wall thickness of the middle drill rod 202, and a plurality of groups of cutter grooves I are arranged in an array along the circumferential direction of the middle drill rod 202.
One end of the inner needle core 203 is opened and extends out of the middle drill rod 202, a suction pipe 205 is arranged through a rotary joint, a suction pump 206 such as a peristaltic pump is arranged at the tail end of the suction pipe 205, the other end of the inner needle core 203 is closed and is flush with the end of the middle drill rod 202, a knife groove II is further arranged at the end of the inner needle core 203, the knife groove II is communicated with the knife groove I, a plurality of groups of knife grooves I are arranged corresponding to the knife groove II, the groove walls of the knife groove II in the circumferential direction of the inner needle core 203 are also obliquely arranged, and when the inner needle core 203 rotates along with the drilling of the middle drill rod 202, bone meal generated by drilling is pulled away from the axial lead of the inner needle core 203 by the oblique groove walls of the knife groove II.
In addition, referring to fig. 5, a first thread groove 2021 is formed on the inner wall of the middle drill rod 202, one end of the first thread groove 2021 is connected with the second thread groove, and the connection point is located at the connection position of the first thread groove and the second thread groove, so that bone meal generated by drilling is finally located in the first thread groove 2021.
Referring to fig. 5, the outer circumferential surface of the inner core 203 is provided with a hole 2031 penetrating through the wall thickness, the hole 2031 is close to the closed end of the inner core 203, and in the initial state, the outer hole of the hole 2031 is blocked by the inner wall of the middle drill pipe 202 and is not communicated with the thread groove one 2021.
Referring to fig. 6, a second thread groove 2022 is further formed in the inner wall of the middle drill rod 202, the pitch of the second thread groove 2022 is the same as the pitch of the first thread groove 2021, the outer circumferential surface of the inner needle core 203 is provided with a ball pin 204, and the ball pin 204 is partially located in the second thread groove 2022, and in addition, when the middle drill rod 202 performs drilling rotation, the inner needle core 203 has an upward movement tendency due to the cooperation of the second thread groove 2022 and the ball pin 204.
The working procedure of the first embodiment is shown as follows:
the medical staff holds the handle provided on the outer housing 100 to pierce the puncture needle set 200 into the patient:
firstly, the middle drill rod 202 and the inner needle core 203 are both positioned in the outer needle sleeve 201 at first, the skin of a patient is pierced through the outer needle sleeve 201 and contacted with bones, and then a medical staff only needs to hold a handle stably;
then, the driving source drives the middle drill rod 202 and the inner needle core 203 to synchronously perform feeding movement, and simultaneously drives the middle drill rod 202 to perform drilling rotation, the middle drill rod 202 rotates to enable the inner needle core 203 to have an upward movement trend through the cooperation of the threaded groove two 2022 and the ball pin 204, and because the inner needle core 203 is driven by the driving source to perform feeding movement, the feeding movement direction is opposite to the upward movement trend direction of the inner needle core 203, the middle drill rod 202 and the inner needle core 203 can be regarded as a whole under the action of drilling rotation, namely, when the middle drill rod 202 performs drilling rotation, the inner needle core 203 is driven by the driving source to synchronously perform feeding movement, namely, the middle drill rod 202 and the inner needle core 203 synchronously perform drilling rotation, in the process, the middle drill rod 202 and the inner needle core 203 form a complete drill bit for performing bone drilling, and bone meal generated by drilling is pulled into the threaded groove one 2021 through cooperation of the cutter groove two;
after drilling is completed, the drilling operation is stopped, and then the driving source drives the inner needle core 203 to extend into the bone, during the process, the drill rod 202 is restrained, so that the inner needle core 203 extends into the bone and rotates under the cooperation of the thread groove two 2022 and the ball pin 204, the inner needle core is used for communicating the hole 2031 with the bone, and during the moving process of the inner needle core 203, the thread pitch of the thread groove two 2022 is the same as the thread pitch of the thread groove one 2021, so that the hole 2031 is not communicated with the thread groove one 2021, that is, during the communication process of the hole 2031 and the bone, the hole 2031 is not contacted with the bone powder;
in summary, at this time, the automatic bone drilling is completed and the hole 2031 is extended into the bone without any contact with bone powder;
suction pump 206 then initiates a suction sampling of bone marrow stem cells.
In the above process: on the one hand, automatic operation is realized, medical personnel only need steadily hold the handle can, can make this puncture sampling device take place not rock the skew, has reduced the pain that receives when patient's marrow puncture greatly, on the other hand, has realized not blockking up the sample, and the one-time sampling can succeed, can not take place the jam problem.
Example two
In one embodiment, in the process of puncturing and sampling the puncture needle set 200, the driving source needs to drive the middle drill rod 202 and the inner needle core 203 to synchronously perform feeding movement, drive the middle drill rod 202 to perform drilling rotation, and drive the inner needle core 203 to independently perform movement, that is, it is easy to think by a person skilled in the art that at least three powers are needed to implement the above actions, on one hand, the power is too much, the line is easy to be complicated, the usage is very inconvenient, on the other hand, the above actions are not smooth, and have a pause, the puncture efficiency is easy to be affected, the time spent on bone marrow puncture is increased, as well known, the shorter the time spent on bone marrow puncture is, the longer the time spent on a patient is, the pain suffered by the patient is more serious, therefore, the driving source needs to be improved, so as to save the puncture time, reduce the pain of the patient, and the following:
referring to fig. 6, an outer shoulder is provided at the outside of the inner core 203, an inner shoulder is provided at the inner wall of the middle drill rod 202, and initially, an upper end surface of the outer shoulder contacts with a lower end surface of the inner shoulder.
Referring to fig. 3 and 7-11, the inner frame 102 is disposed in the outer housing 100, and the driving source includes a driving mechanism 300 mounted on the inner frame 102 for driving the puncture needle set 200 to perform a bone marrow puncturing operation by means of a single power source, and a limiting member 400 for limiting the depth of the drilling operation to prevent the occurrence of transitional drilling.
Referring to fig. 1, 3 and 7, the limiting member 400 includes a second screw 402 mounted on the inner frame 102, the second screw 402 being parallel to the outer needle sheath 201, an input end of the second screw 402 extending out of the outer housing 100 and being provided with a knob 401, and the second screw 402 being rotated by the knob 401.
The limiting member 400 further comprises a limiting bracket 403 axially slidably mounted on the inner frame 102 along the second screw rod 402, the limiting bracket 403 is in threaded connection with the second screw rod 402, when the second screw rod 402 rotates, the limiting bracket 403 can be driven to move, and in addition, an avoidance hole for avoiding the puncture needle set 200 is formed in the limiting bracket 403.
The outer surface of the outer shell 100 is provided with a marking hole, one side of the marking hole is provided with a scale mark 101, a marking plate 404 extends on the limiting bracket 403, and the tail end of the marking plate 404 is positioned in the marking hole; the second screw rod 402 is rotated through the rotation knob 401, the limiting support 403 and the marking plate 404 are further moved, the moving distance of the marking plate 404 is observed through the scale marks 101, the limiting support 403 is located at a preset height, in addition, a patient is scanned in advance through the prior art, the bone wall thickness of the patient is obtained, and the height of the limiting support 403 is adjusted through the bone wall thickness, so that the patient is located at the preset height.
Referring to fig. 8, the drive mechanism 300 includes a motor 301, a differential 302, and a first lead screw 304 and a drive spur gear 303 mounted on the inner frame 102 and parallel to a second lead screw 402, wherein the differential 302 includes an input shaft, two output half shafts: the first output half shaft is in power connection with the second output half shaft, the input shaft is in power connection with the motor 301, the first output half shaft is in power connection with the first screw rod 304, and the second output half shaft is in power connection with the driving spur gear 303.
The driven spur gear 305 is mounted on the outer portion of the middle drill rod 202, the driven spur gear 305 is meshed with the driving spur gear 303, the axial length of the driving spur gear 303 is larger than that of the driven spur gear 305, when the middle drill rod 202 moves together with the driven spur gear 305, the driven spur gear 305 and the driving spur gear 303 are kept meshed, and power is continuously output to the middle drill rod 202.
The connecting bracket 306 is installed outside the first screw rod 304, and the connecting bracket 306 is matched with the inner frame 102 in a sliding guide way along the axial direction of the first screw rod 304, so that when the first screw rod 304 rotates, the connecting bracket 306 moves.
The connecting support 306 is connected with the inner needle core 203 through a bearing, the connecting support 306 is connected with the middle drill rod 202 through a connecting component 307, and the following concrete is that:
referring to fig. 9 and 10, the connecting assembly 307 includes an outer sleeve 3071 axially slidably mounted on the inner frame 102 along the first screw rod 304, an inner sleeve 3073 is slidably mounted inside the outer sleeve 3071, a first spring 3074 is disposed between the inner sleeve 3073 and the outer sleeve 3071, and the elastic force of the first spring 3074 is used for driving the inner sleeve 3073 to move downward, so that the bottom of the inner sleeve 3073 is located between the outer sleeve 3071 and the limiting bracket 403.
The inner part of the outer sleeve 3071 is also provided with a limiting block 3075 in a sliding manner along the horizontal direction, the limiting block 3075 is provided with two groups along the sliding direction, a second spring 3076 is arranged between the two groups of limiting blocks 3075, the opposite side surfaces of the two groups of limiting blocks 3075 extend out of the outer sleeve 3071 and consist of an upper plane and a lower inclined plane, the upper plane is parallel to the outer sleeve 3071, and the distance between the lower inclined planes of the two groups of limiting blocks 3075 increases gradually from bottom to top.
The bottom of stopper 3075 is provided with the bottom inclined plane, and the bottom inclined plane is located the overcoat post 3071 inside, and the distance between the bottom inclined plane of two sets of stopper 3075 increases gradually from bottom to top, and the top of interior post 3073 is provided with the top inclined plane, and top inclined plane and bottom inclined plane laminating.
Referring to fig. 9, the connecting bracket 306 is provided with a first sleeve hole, and the outer sleeve 3071 is movably sleeved in the first sleeve hole, and in an initial state, the lower orifice of the first sleeve hole contacts with the upper end surface of the limiting block 3075.
Referring to fig. 3 and 7, a second sleeve hole is formed in the limiting bracket 403, the second sleeve hole coaxially surrounds the periphery of the middle drill rod 202, a protruding pin 405 extends from the upper end surface of the limiting bracket 403, a pin hole is formed in the bottom of the driven spur gear 305, and the pin hole is coaxially located above the protruding pin 405.
Referring to fig. 3, 9 and 11, a boss 3072 extends from the bottom of the outer sleeve 3071, a third sleeve hole is formed in the boss 3072, the middle drill rod 202 is movably sleeved in the third sleeve hole, a clamping ring is mounted on the outer portion of the middle drill rod 202, the lower end face of the clamping ring contacts with the upper orifice of the third sleeve hole, a third spring 309 is arranged between the lower orifice of the third sleeve hole and the upper end face of the driven spur gear 305, and it is noted that the elastic coefficient of the third spring 309 is larger.
Referring to fig. 9 and 11, a pawl assembly 308 is provided at the bottom of the ledge 3072, the pawl assembly 308 includes a pawl 3081 hingedly provided at the bottom of the ledge 3072 and a coil spring 3082 provided between the hinge shaft and the ledge 3072, the end of the pawl 3081 is inserted between adjacent engagement teeth of the driven spur gear 305, and the pawl assembly 308 and the driven spur gear 305 together form a ratchet pawl structure for enabling only drilling rotation of the driven spur gear 305 but not reverse rotation.
The working procedure of the second embodiment is as follows:
scanning a patient by the prior art before puncture sampling to obtain the bone wall thickness of the patient, and adjusting the height of the limit bracket 403 by the bone wall thickness to enable the limit bracket to be at a preset height;
during penetration, after the outer needle hub 201 is in contact with bone, the motor 301 is activated to operate:
firstly, the first screw rod 304 and the driving spur gear 303 are driven to rotate together through the differential mechanism 302, the first screw rod 304 drives the connecting support 306 to move downwards (downwards movement refers to feeding movement), the connecting support 306 directly drives the inner needle core 203 to move downwards, the middle drill rod 202 is driven to move downwards through the connecting component 307, the second screw rod 202 is driven to rotate, after the first cutter groove is contacted with the second cutter groove and the bone, the downwards movement is blocked, the power distributed to the driving spur gear 303 is increased, after the bone drills out to a depth, the downwards movement is blocked and disappears, and the power is distributed to the first screw rod 304 again, so that the drilling action of the bone is realized;
when the drilling is completed, the inner slide 3073 in the connecting assembly 307 is contacted with the limit bracket 403, the protruding pin is contacted with the lower end surface of the driven straight gear 305, then the protruding pin is inserted into the pin hole by slightly repeating the drilling operation, the outer slide 3071 is continuously moved down but the inner slide 3073 is not moved, the limit block 3075 is retracted into the outer slide 3071 under the cooperation of the bottom inclined plane and the top inclined plane, and the connecting bracket 306 is beyond the limit block 3075;
then, because the rotation of the driven straight gear 305 is limited by the convex pin and the pin hole, the power of the motor 301 is distributed to the first screw rod 304 to enable the inner needle core 203 to move downwards and extend into the bone, and meanwhile, because the connecting bracket 306 passes over the limiting block 3075, the connecting bracket 306 moves and cannot move downwards together with the drill rod 202 in traction through the connecting assembly 307;
thus, drilling is completed, the suction hole 2031 on the inner needle core 203 is extended into the bone, and suction sampling is performed by the suction pump 206.
After the sampling is finished, the motor 301 runs reversely, the driven spur gear 305 cannot rotate reversely to the drilling rotation due to the pawl assembly 308, so that the power of the motor 301 is distributed to the screw rod one 304, the connecting bracket 306 moves upwards, the inner needle core 203 moves upwards firstly by the upward movement of the connecting bracket 306, the position relationship between the inner needle core 203 and the middle drill rod 202 is restored, the inner needle core 203 and the middle drill rod 202 are pulled to move upwards by the cooperation of the inner shaft shoulder and the outer shaft shoulder, the position relationship between the puncture needle set 200 and the inner frame 102 is reset, at the moment, the puncture needle set 200 is reset, in addition, in the process, the upward movement of the connecting bracket 306 also firstly moves upwards by pushing the limiting block 3075 to bring the connecting assembly 307 upwards, after the position relationship between the connecting assembly 307 and the inner frame 102 is restored, the puncture needle set 200 is not reset, the connecting bracket 306 needs to move upwards continuously to reset the puncture needle set 200, and in the stage, the position relationship between the connecting bracket 306 and the connecting assembly 307 is reset, and the whole puncture needle set is reset is driven to complete, and the puncture needle set is reset, and the whole device is reset, and the puncture needle set is reset.
In the above process, the feeding movement of the middle drill rod 202 and the inner needle core 203 is synchronously performed by the single power source driving mode (the motor 301), the drilling rotation of the middle drill rod 202 and the independent movement of the inner needle core 203 are performed, and the advantage of the method is that the three actions are smoothly connected without delay, so that the efficiency of bone marrow puncture completion can be quickened, the pain time of a patient is reduced, besides, the differential mechanism 302 can correspondingly distribute the power of the motor 301 according to the three action stages, the power is not wasted, the three actions are driven by enough power, for example, when the independent movement of the inner needle core 203 is performed, the power of the motor 301 is completely distributed to the first screw rod 304, namely, the independent movement of the inner needle core 203 is distributed, and the inner needle core 203 can rapidly extend into the bone.
The present invention is not limited to the above embodiments, but is capable of modification and variation in detail, and other modifications and variations can be made by those skilled in the art without departing from the scope of the present invention.

Claims (3)

1. The utility model provides a marrow stem cell draws and uses puncture sampling device, includes shell body (100) and sets up puncture needle group (200) and driving source on shell body (100), its characterized in that: the puncture needle group (200) comprises an outer needle sleeve (201) vertically arranged at the bottom of the outer shell (100), a middle drill rod (202) is sleeved in the inner hollow part of the outer needle sleeve (201), and an inner needle core (203) is sleeved in the inner hollow part of the middle drill rod (202);
the surface of the middle drill rod (202) is smooth, a cutter groove I is formed in the end part of the middle drill rod (202), the cutter groove I is obliquely arranged along the groove wall of the middle drill rod (202) in the circumferential direction, when the middle drill rod (202) performs drilling action, bone meal generated by drilling is pulled towards the axial lead of the middle drill rod (202) by the oblique groove wall of the cutter groove I, one end of an inner needle core (203) is opened and extends out of the middle drill rod (202), a suction pipe (205) is arranged through a rotary joint, the tail end of the suction pipe (205) is provided with a suction pump (206), the other end of the inner needle core (203) is sealed and is flush with the end part of the middle drill rod (202) provided with the cutter groove I, the end of the inner needle core (203) is provided with a cutter groove II which is communicated with the cutter groove I, the cutter groove II is obliquely arranged along the groove wall of the circumferential direction of the inner needle core (203), and when the inner needle core (203) rotates along with the middle drill rod (202), the bone meal generated by drilling is pulled away from the axial lead of the inner needle core (203) by the oblique groove wall of the cutter groove II;
the inner wall of the middle drill rod (202) is provided with a first thread groove (2021), one end of the first thread groove (2021) is communicated with the knife groove, a communication point is positioned at the communication position of the first knife groove and the second knife groove, the outer circular surface of the inner needle core (203) is provided with a drawing hole (2031) penetrating through the wall thickness, the drawing hole (2031) is close to the closed end of the inner needle core (203), and the outer hole opening of the drawing hole (2031) is blocked by the inner wall of the middle drill rod (202);
the inner wall of the middle drill rod (202) is provided with a thread groove II (2022), the outer circular surface of the inner needle core (203) is provided with a ball pin (204), the ball pin (204) is partially positioned in the thread groove II (2022), and when the middle drill rod (202) rotates in a drilling mode, the thread groove II (2022) and the ball pin (204) cooperate to enable the inner needle core (203) to move upwards;
an inner frame (102) is arranged in the outer shell (100), the driving source comprises a driving mechanism (300) and a limiting member (400) which are arranged on the inner frame (102), the driving mechanism (300) is used for driving the puncture needle set (200) to perform bone marrow puncture action in a single power source mode, and the limiting member (400) is used for limiting the depth of the drilling action;
the limiting member (400) comprises a second screw rod (402) arranged on the inner frame (102), the second screw rod (402) is parallel to the outer needle sleeve (201), and the input end of the second screw rod (402) extends out of the outer shell (100) and is provided with a knob (401);
a limiting bracket (403) is arranged on the second screw rod (402), and the limiting bracket (403) and the inner frame (102) form sliding guide fit along the axial direction of the second screw rod (402);
the outer surface of the outer shell (100) is provided with a marking hole, one side of the marking hole is provided with a scale mark (101), a marking plate (404) extends on the limiting bracket (403), and the tail end of the marking plate (404) is positioned in the marking hole;
an outer shaft shoulder is arranged outside the inner needle core (203), an inner shaft shoulder is arranged on the inner wall of the middle drill rod (202), and the upper end face of the outer shaft shoulder is contacted with the lower end face of the inner shaft shoulder in the initial stage;
the driving mechanism (300) comprises a motor (301) and a differential mechanism (302), a first screw rod (304) parallel to a second screw rod (402) is arranged on the inner frame (102) and is in power connection with the driving spur gear (303), an input shaft of the differential mechanism (302) and the motor (301) form power connection, an output half shaft of the differential mechanism (302) and the first screw rod (304) form power connection, the second output half shaft of the differential mechanism (302) and the driving spur gear (303) form power connection, a driven spur gear (305) meshed with the driving spur gear (303) is arranged outside the middle drill rod (202), and the driving spur gear (303) is meshed with the driven spur gear (305) when the middle drill rod (202) moves together with the driven spur gear (305);
a connecting bracket (306) is arranged outside the first screw rod (304), the connecting bracket (306) and the inner frame (102) form sliding guide fit along the axial direction of the first screw rod (304), the connecting bracket (306) is connected with the inner needle core (203) through a bearing, and the connecting bracket (306) is connected with the middle drill rod (202) through a connecting component (307);
the connecting assembly (307) comprises an outer sleeve column (3071) which is axially and slidably arranged on the inner frame (102) along the first screw rod (304), an inner sleeve column (3073) is slidably arranged in the outer sleeve column (3071), a first spring (3074) is arranged between the inner sleeve column (3073) and the outer sleeve column (3071), and the bottom of the inner sleeve column (3073) is positioned between the outer sleeve column (3071) and the limiting support (403);
the inside of the outer sleeve column (3071) is also provided with limiting blocks (3075) in a sliding manner along the horizontal direction, the limiting blocks (3075) are provided with two groups along the sliding direction, springs II (3076) are arranged between the two groups of limiting blocks (3075), the opposite side surfaces of the two groups of limiting blocks (3075) extend out of the outer sleeve column (3071) and consist of an upper plane and a lower inclined plane, the upper plane is parallel to the outer sleeve column (3071), and the distance between the lower inclined planes of the two groups of limiting blocks (3075) is increased from bottom to top;
the bottom of the limiting block (3075) is provided with a bottom inclined plane, the bottom inclined plane is positioned inside the outer sleeve column (3071), the distance between the bottom inclined planes of the two groups of limiting blocks (3075) increases gradually from bottom to top, the top of the inner sliding column (3073) is provided with a top inclined plane, and the top inclined plane is attached to the bottom inclined plane;
a first sleeve hole is formed in the connecting bracket (306) and the outer sleeve column (3071) is sleeved in the first sleeve hole, and initially, the lower orifice of the first sleeve hole is contacted with the upper end face of the limiting block (3075);
a second trepanning is formed in the limiting support (403) and coaxially surrounds the periphery of the middle drill rod (202), a protruding pin (405) extends from the upper end face of the limiting support (403), a pin hole is formed in the bottom of the driven straight gear (305), and the pin hole is coaxially located above the protruding pin (405);
the bottom of the outer sleeve column (3071) is extended to form a convex frame (3072), a sleeve hole III is formed in the convex frame (3072), the middle drill rod (202) is movably sleeved in the sleeve hole III, a clamping ring is arranged outside the middle drill rod (202), the lower end face of the clamping ring is in contact with the upper orifice of the sleeve hole III, and a spring III (309) is arranged between the lower orifice of the sleeve hole III and the upper end face of the driven spur gear (305).
2. The puncture sampling device for bone marrow stem cell extraction according to claim 1, wherein: the pitch of thread groove two (2022) is the same as the pitch of thread groove one (2021).
3. The puncture sampling device for bone marrow stem cell extraction according to claim 1, wherein: the bottom of the convex frame (3072) is provided with a pawl assembly (308), the pawl assembly (308) and the driven straight gear (305) jointly form a ratchet pawl structure, and the ratchet pawl structure is used for enabling the driven straight gear (305) to only rotate through drilling.
CN202311401225.3A 2023-10-26 2023-10-26 Bone marrow stem cell draws with puncture sampling device Active CN117122353B (en)

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WO2008033874A2 (en) * 2006-09-12 2008-03-20 Vidacare Corporation Bone marrow aspiration devices and related methods
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WO2022261632A1 (en) * 2021-06-10 2022-12-15 Merit Medical Systems, Inc. Bone biopsy device and related methods

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101229072A (en) * 2007-01-23 2008-07-30 株式会社Jimro Bone marrow harvesting drill
CN110035702A (en) * 2016-10-24 2019-07-19 耶鲁大学 Sting device
CN112603387A (en) * 2021-01-05 2021-04-06 邓爱娣 Bone marrow extraction element that blood internal medicine used
CN215605925U (en) * 2021-06-10 2022-01-25 上海宏创医疗科技有限公司 Marrow biopsy needle
CN218279689U (en) * 2021-12-13 2023-01-13 真健康(北京)医疗科技有限公司 Bone tissue aspiration biopsy sampling needle core and bone tissue aspiration biopsy needle

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