CN116943032B

CN116943032B - Electrical stimulation generating device, method, electronic device, and storage medium

Info

Publication number: CN116943032B
Application number: CN202311214473.7A
Authority: CN
Inventors: 白洋
Original assignee: Jiangxi Jingyi Medical Technology Co ltd
Current assignee: Jiangxi Jingyi Medical Technology Co ltd
Priority date: 2023-09-20
Filing date: 2023-09-20
Publication date: 2024-01-09
Anticipated expiration: 2043-09-20
Also published as: CN116943032A

Abstract

The application discloses an electrical stimulation generating device, an electrical stimulation generating method, an electronic device and a storage medium. Comprising the following steps: the device comprises a central processing unit, a low-voltage stimulation module, a high-voltage stimulation module and a regulation and control module; the central processing unit is connected with the low-voltage stimulation module, the high-voltage stimulation module and the regulation and control module and is used for receiving external information for processing and sending corresponding signal parameters to the low-voltage stimulation module, the high-voltage stimulation module or the regulation and control module according to the processing result; the regulation and control module is connected with the high-voltage electric stimulation module and is used for analyzing the signal parameters after receiving the signal parameters; the low-voltage stimulation module is connected with the first output electrode and is used for generating corresponding low-voltage stimulation according to the signal parameter or the low-voltage signal after receiving the signal parameter or the low-voltage signal; the high-voltage electric stimulation module is connected with the second output electrode and is used for generating corresponding high-voltage electric stimulation according to the signal parameter or the high-voltage signal after receiving the signal parameter or the high-voltage signal.

Description

Electrical stimulation generating device, method, electronic device, and storage medium

Technical Field

The invention relates to the technical field of medical treatment, in particular to an electric stimulation generating device, an electric stimulation generating method, electronic equipment and a storage medium.

Background

Current electrical stimulation therapies are widely applicable in a variety of disease areas, for example: the stimulation of different waveforms is carried out on the brain, limb, nerve and other parts to achieve the diagnosis or treatment effect. Meanwhile, the electrical stimulation therapy generally includes a piezoelectric stimulation therapy and a high-voltage stimulation therapy. The voltage of the current piezoelectric stimulation therapy can reach about 100V according to the difference between the treatment symptoms and the treatment methods. The high-voltage stimulation therapy generally aims at the trunk diseases to perform corresponding electric stimulation, and the voltage of the current high-voltage stimulation therapy can reach about 350V according to the differences of treatment symptoms and treatment methods, so that the voltage span is larger. However, for the current electrical stimulation treatment of various diseases, a special stimulation generating device is used, and the device can only generate corresponding waveforms and corresponding voltage range stimulation for corresponding disease symptoms according to a preset waveform scheme when the device comes out, but cannot generate voltage stimulation required by waveforms and other treatment schemes required by other diseases. Therefore, it is often necessary to purchase the corresponding stimulus generating equipment separately for each disease, which greatly increases the cost.

Disclosure of Invention

In order to solve the above problems in the prior art, the embodiment of the application provides an electrical stimulation generating device, an electrical stimulation generating method, an electronic device and a storage medium, which can realize free editing and definition of waveforms, and then realize generation of waveform stimulation required by all diseases through one device, thereby greatly reducing cost.

In a first aspect, embodiments of the present application provide an electrical stimulation generating device, the device comprising: the device comprises a central processing unit, a low-voltage stimulation module, a high-voltage stimulation module and a regulation and control module;

wherein,

the central processing unit is respectively connected with the low-voltage stimulation module, the high-voltage stimulation module and the regulation and control module, wherein the central processing unit is used for receiving external information for processing and sending corresponding signal parameters to the low-voltage stimulation module, the high-voltage stimulation module or the regulation and control module according to a processing result;

the control module is respectively connected with the low-voltage stimulation module and the high-voltage stimulation module, wherein the control module is used for analyzing the signal parameters after receiving the signal parameters to obtain low-voltage parameters and high-voltage parameters, sending the low-voltage parameters to the low-voltage stimulation module and sending the high-voltage parameters to the high-voltage stimulation module;

The low-voltage stimulation module is connected with the first output electrode, wherein the low-voltage stimulation module is used for generating corresponding low-voltage stimulation according to the signal parameter or the low-voltage signal after receiving the signal parameter or the low-voltage signal, and outputting the low-voltage stimulation based on the first output electrode, and the highest value of the output voltage of the low-voltage stimulation is 100V;

the high-voltage stimulation module is connected with the second output electrode, wherein the high-voltage stimulation module is used for generating corresponding high-voltage stimulation according to the signal parameter or the high-voltage signal after receiving the signal parameter or the high-voltage signal, and outputting the high-voltage stimulation based on the second output electrode, and the highest value of the output voltage of the high-voltage stimulation is 350V;

the external information comprises prescription information, the external information is received and processed based on the prescription information, and corresponding signal parameters are sent to the low-voltage stimulation module, the high-voltage stimulation module or the regulation and control module according to the processing result, and the central processing unit is specifically used for:

matching is carried out in a treatment prescription library according to prescription information to obtain a matching result, wherein the treatment prescription library comprises a plurality of treatment schemes;

if the matching result contains the treatment scheme, taking the parameters in the treatment scheme as signal parameters;

If the matching result does not contain the treatment scheme, a regulation and control interface is displayed for a user, so that the user invokes a stimulation waveform library to edit the stimulation signals through the regulation and control interface, wherein the stimulation waveform library comprises a plurality of basic stimulation waveforms;

receiving editing parameters of a user in a regulation interface, and taking the editing parameters as signal parameters;

determining a stimulation mode according to the signal parameters;

and sending the signal parameters to a piezoelectric stimulation module, a high-voltage stimulation module or a regulation and control module according to the stimulation mode.

In one possible implementation, the central processing unit is specifically configured to, in matching in the treatment prescription library according to the prescription information, obtain a matching result:

extracting features of diagnosis information and disease information in the prescription information to obtain prescription feature vectors;

calculating a model of a prescription feature vector, and calculating a model of a treatment feature vector corresponding to each of a plurality of treatment schemes in a treatment prescription library;

calculating the product of the module of the prescription characteristic vector and the module of the treatment characteristic vector corresponding to each treatment scheme to obtain a product value;

calculating the inner product of the prescription characteristic vector and the treatment characteristic vector corresponding to each treatment scheme to obtain an inner product value;

Taking the quotient of the inner product value and the product value as prescription information and the similarity of each treatment scheme;

and determining whether the similarity greater than a preset threshold exists in the plurality of similarities, if so, enabling the treatment scheme corresponding to the maximum value in the plurality of similarities to serve as a matching result, and if not, enabling the matching result to be null.

In one possible embodiment, the piezoelectric stimulation module comprises:

the device comprises a stimulation signal generator, a first constant current source, a current equalizer and a time-sharing switch selection component;

wherein,

one end of the stimulation signal generator is connected with the central processing unit, and the stimulation signal generator is used for receiving signal parameters sent by the central processing unit and generating corresponding low-voltage waveform signals based on the signal parameters;

the other end of the stimulation signal generator is connected with one end of a first constant current source, and the first constant current source is used for generating a corresponding low-voltage stimulation signal according to the low-voltage waveform signal;

the other end of the first constant current source is connected with one end of the current equalizer, and the current equalizer is used for determining the number of output lines according to signal parameters and equalizing the current in the output lines;

the other end of the current equalizer is connected with one end of a time-sharing switch selection component, the time-sharing switch selection component comprises a processor and a plurality of first output ports, the processor is used for determining output time, output duration and output signals of each of the plurality of first output ports according to signal parameters, and the plurality of first output ports are used for outputting low-voltage stimulation signals.

In one possible embodiment, the high voltage stimulation module comprises:

the device comprises a current controller, a pulse signal generator, a second constant current source and an isolated current transducer;

wherein,

one end of the current controller is connected with the central processing unit, and the current controller is used for receiving signal parameters sent by the central processing unit and regulating and controlling the current according to the signal parameters;

the other end of the current controller is connected with one end of a pulse signal generator, and the pulse signal generator is used for generating a high-voltage waveform signal according to signal parameters;

the other end of the pulse signal generator is connected with one end of a second constant current source, and the second constant current source is used for generating a corresponding high-voltage stimulation signal according to the high-voltage waveform signal;

the other end of the second constant current source is connected with an isolation current transducer, the isolation current transducer comprises an isolator and a plurality of second output ports, the isolator is used for isolating the second constant current source and a tested person, and the plurality of second output ports are used for outputting high-voltage stimulation signals.

In one possible embodiment, the regulation module comprises:

the device comprises a coupling assembly, a program-controlled variable voltage power supply assembly and an electrode contact quality acquisition assembly;

wherein,

the coupling component is respectively connected with the central processing unit, the stimulation signal generator and the pulse signal generator, and is used for receiving signal parameters from the central processing unit, analyzing the signal parameters, sending the analyzed low-voltage parameters to the stimulation signal generator, and sending the analyzed high-voltage parameters to the pulse signal generator;

The program-controlled variable voltage power supply assembly is respectively connected with the central processing unit, the first constant current source and the second constant current source, and is used for receiving voltage adjustment parameters from the central processing unit and sending the voltage adjustment parameters to the first constant current source and/or the second constant current source so as to regulate and control the output voltage of the first constant current source and/or the second constant current source;

the electrode contact quality acquisition component is respectively connected with the central processing unit, the first constant current source and the second constant current source, and is used for acquiring the voltage of the first constant current source and/or the second constant current source and sending the voltage of the first constant current source and/or the second constant current source to the central processing unit so that the central processing unit can determine the contact quality between the first output electrode and/or the second output electrode and a tested person according to the voltage of the first constant current source and/or the second constant current source.

In one possible embodiment, the apparatus further comprises:

the alarm assembly is connected with the central processing unit, and the alarm assembly triggers corresponding audible and visual alarm according to the alarm signal after receiving the alarm signal sent by the central processing unit.

In one possible embodiment, the output voltage of the high voltage electrical stimulus is in the range of 0V-100V and the output voltage of the high voltage electrical stimulus is in the range of 100V-350V.

In a second aspect, embodiments of the present application provide an electrical stimulation generating method applied to an electrical stimulation generating device, the electrical stimulation generating device including: the system comprises a central processing unit, a low-voltage stimulation module, a high-voltage stimulation module and a regulation and control module, wherein the method comprises the following steps:

the central processing unit receives external information for processing and sends corresponding signal parameters to the piezoelectric stimulation module, the high-voltage stimulation module or the regulation and control module according to the processing result;

when the low-voltage stimulation module receives the signal parameters, the low-voltage stimulation module generates corresponding low-voltage stimulation signals according to the signal parameters to output, and the highest output voltage of the low-voltage stimulation is 100V;

when the high-voltage stimulation module receives the signal parameters, the high-voltage stimulation module generates corresponding high-voltage stimulation signals according to the signal parameters to output, and the highest output voltage of the high-voltage stimulation is 350V;

when the regulation and control module receives the signal parameters, the regulation and control module analyzes the signal parameters to obtain low-voltage parameters and high-voltage parameters, the low-voltage parameters are sent to the low-voltage stimulation module, the high-voltage parameters are sent to the high-voltage stimulation module, so that the low-voltage stimulation module generates corresponding low-voltage stimulation signals according to the low-voltage parameters, and the high-voltage stimulation module generates corresponding high-voltage stimulation signals according to the high-voltage parameters to synchronously output the corresponding high-voltage stimulation signals;

The external information comprises prescription information, the prescription information is received and processed, corresponding signal parameters are sent to the piezoelectric stimulation module, the high-voltage stimulation module or the regulation and control module according to the processing result, and the central processing unit is specifically used for:

determining a stimulation mode according to the signal parameters;

In a third aspect, embodiments of the present application provide an electronic device, including: and a processor coupled to the memory, the memory for storing a computer program, the processor for executing the computer program stored in the memory to cause the electronic device to perform the method as in the second aspect.

In a fourth aspect, embodiments of the present application provide a computer-readable storage medium storing a computer program that causes a computer to perform the method as in the second aspect.

In a fifth aspect, embodiments of the present application provide a computer program product comprising a non-transitory computer readable storage medium storing a computer program, the computer being operable to cause a computer to perform a method as in the second aspect.

The implementation of the embodiment of the application has the following beneficial effects:

it can be seen that in the embodiment of the present application, the signal parameters of the corresponding electrical stimulation waveforms are determined by receiving external information, such as prescription information of the patient to be treated. The signal parameters are then sent to the corresponding signal generation modules, namely: the high-voltage stimulation module is used for generating corresponding electric stimulation and outputting the generated electric stimulation. Therefore, free editing and definition of waveforms are realized, and then waveform stimulation required by all diseases is generated through one device, so that the cost is greatly reduced.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings that are needed in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present application, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

Fig. 1 is a schematic hardware structure of an electrical stimulation generating device according to an embodiment of the present application;

fig. 2 is a block diagram of an electrical stimulation generating device according to an embodiment of the present application;

fig. 3 is a schematic diagram of an electrical stimulation generating device according to an embodiment of the present application;

fig. 4 is a schematic flow chart of an electrical stimulation generating method according to an embodiment of the present application;

fig. 5 is a schematic structural diagram of an electronic device according to an embodiment of the present application.

Detailed Description

The following description of the embodiments of the present application will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are some, but not all, of the embodiments of the present application. All other embodiments, based on the embodiments herein, which would be apparent to one of ordinary skill in the art without undue burden are within the scope of the present application.

The terms "first," "second," "third," and "fourth" and the like in the description and in the claims of this application and in the drawings, are used for distinguishing between different objects and not for describing a particular sequential order. Furthermore, the terms "comprise" and "have," as well as any variations thereof, are intended to cover a non-exclusive inclusion. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those listed steps or elements but may include other steps or elements not listed or inherent to such process, method, article, or apparatus.

Reference herein to "an embodiment" means that a particular feature, result, or characteristic described in connection with the embodiment may be included in at least one embodiment of the application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein may be combined with other embodiments.

Next, referring to fig. 1, fig. 1 is a schematic hardware structure of an electrical stimulation generating device according to an embodiment of the present application. The electrical stimulation generating apparatus 100 comprises at least one processing device 101, a communication line 102, a memory 103 and at least one communication interface 104.

In this embodiment, the processing device 101 may be a general purpose central processing device (central processing unit, CPU), a micro-processing device, an application-specific integrated circuit (ASIC), or one or more integrated circuits for controlling the execution of programs in the present application.

Communication line 102 may include a pathway to transfer information between the above-described components.

The communication interface 104, which may be any transceiver-like device (e.g., antenna, etc.), is used to communicate with other devices or communication networks, such as ethernet, RAN, wireless local area network (wireless local area networks, WLAN), etc.

The memory 103 may be, but is not limited to, a read-only memory (ROM) or other type of static storage device that can store static information and instructions, a random access memory (random access memory, RAM) or other type of dynamic storage device that can store information and instructions, or an electrically erasable programmable read-only memory (electrically erasable programmable read-only memory, EEPROM), a compact disc (compact disc read-only memory) or other optical disc storage, optical disc storage (including compact disc, laser disc, optical disc, digital versatile disc, blu-ray disc, etc.), magnetic disk storage media or other magnetic storage devices, or any other medium that can be used to carry or store desired program code in the form of instructions or data structures and that can be accessed by a computer.

In this embodiment, the memory 103 may exist independently and be connected to the processing device 101 through the communication line 102. Memory 103 may also be integrated with processing device 101. The memory 103 provided by embodiments of the present application may generally have non-volatility. The memory 103 is used for storing computer-executable instructions for executing the embodiments of the present application, and is controlled to be executed by the processing device 101. The processing device 101 is configured to execute computer-executable instructions stored in the memory 103, thereby implementing the methods provided in the embodiments described below in the present application.

In alternative embodiments, computer-executable instructions may also be referred to as application code, which is not specifically limited in this application.

In alternative embodiments, processing device 101 may include one or more CPUs, such as CPU0 and CPU1 in fig. 1.

In alternative embodiments, the electrical stimulation generating apparatus 100 may include a plurality of processing devices, each of which may be a single-core (single-CPU) processing device or a multi-core (multi-CPU) processing device. A processing device herein may refer to one or more devices, circuits, and/or processing cores for processing data (e.g., computer program instructions).

In an alternative embodiment, if the electrical stimulation generating device 100 is a server, for example, it may be a stand-alone server, or may be a cloud server that provides cloud services, cloud databases, cloud computing, cloud functions, cloud storage, network services, cloud communication, middleware services, domain name services, security services, content delivery network (Content Delivery Network, CDN), and basic cloud computing services such as big data and artificial intelligence platform. The electrical stimulation apparatus 100 may further comprise an output device 105 and an input device 106. The output device 105 communicates with the processing device 101 and may display information in a variety of ways. For example, the output device 105 may be a liquid crystal display (liquid crystal display, LCD), a light emitting diode (light emitting diode, LED) display device, a Cathode Ray Tube (CRT) display device, or a projector (projector), or the like. The input device 106 communicates with the processing device 101 and may receive user input in a variety of ways. For example, the input device 106 may be a mouse, a keyboard, a touch screen device, a sensing device, or the like.

The above-described electrical stimulation generating apparatus 100 may be a general-purpose device or a special-purpose device. The embodiment of the present application is not limited to the type of the electrical stimulation generating device 100.

Referring to fig. 2, fig. 2 is a block diagram of an electrical stimulation generating device according to an embodiment of the present application. The electrical stimulation generating device may include: the system comprises a central processing unit 201, a low-voltage stimulation module 301, a high-voltage stimulation module 401 and a regulation and control module 501.

In this embodiment, the central processing unit 201 is connected to the low-voltage stimulation module 301, the high-voltage stimulation module 401, and the regulation module 501, where the central processing unit 201 is configured to receive external information for processing, and send corresponding signal parameters to the low-voltage stimulation module 301, the high-voltage stimulation module 401, or the regulation module 501 according to a processing result.

Specifically, the external information may be prescription information of the subject or patient to be treated. After the patient to be treated is diagnosed by a doctor, the doctor inputs the diagnosis information, the disease information, the treatment information and the like of the patient to be treated into a hospital management system, and the hospital management system gathers and sorts the information to obtain the prescription information. Thus, in this embodiment, the electrical stimulation generating device may further include an external control device, such as a PC or Pad, so that the doctor may access the hospital management system to obtain the prescription information by operating the external control device. Alternatively, identity information may also be entered autonomously by the patient to be treated, for example: the prescription information is obtained autonomously by the identification card number, the patient number, the prescription number and the like.

In this embodiment, after the external control device obtains the information about the treatment place, the prescription information can be sent to the central processing unit 201, and the central processing unit 201 performs analysis and processing. Illustratively, first, the central processor 201 performs matching in the treatment prescription library according to the prescription information, resulting in a matching result. The treatment prescription library is a database maintained by the hospital management system for storing a plurality of treatment protocols. Each of the plurality of treatment regimens is a treatment regimen that has proven viable for a disease, specifically including: disease name, disorder information, regimen information, waveform parameters, and the like. Specifically, feature extraction can be performed on the diagnosis information and the disease information in the prescription information to obtain prescription feature vectors, similarity between the prescription feature vectors and the treatment feature vectors corresponding to each treatment scheme is calculated, whether the similarity larger than a preset threshold exists in the plurality of similarities is then determined, if so, the treatment scheme corresponding to the maximum value in the plurality of similarities is used as a matching result, and if not, the matching result is made to be null.

In this embodiment, the similarity can be calculated as follows:

First, a model of a prescription feature vector is calculated, and a model of a treatment feature vector corresponding to each of a plurality of treatment plans in a treatment prescription library is calculated. Illustratively, assume a prescription feature vector x= [ X1, X2, …, xi, …, xn ], and a treatment feature vector y= [ Y1, Y2, …, yi, …, yn ], where i=1, 2, …, n, for each treatment regimen. The modulus of the prescription feature vector X can be expressed by the formula (1):

then, the product of the module of the prescription feature vector and the module of the therapeutic feature vector corresponding to each therapeutic scheme is calculated to obtain a product value, and the inner product of the prescription feature vector and the therapeutic feature vector corresponding to each therapeutic scheme is calculated to obtain an inner product value. Wherein the inner product of the prescribed feature vector X and the treatment feature vector Y corresponding to each treatment plan can be represented by formula (2):

finally, the quotient of the inner product value and the product value is taken as the similarity of prescription information and each treatment scheme. That is, the similarity can be expressed by the formula (3):

wherein P is the similarity of prescription information and each treatment regimen.

In the present embodiment, the similarity has a value in the range of [ -1,1], and thus, even in the case of a high dimension, the similarity has the property of being 1 when the same, 0 when the same is orthogonal, and-1 when the same is opposite. That is, the closer the similarity approaches 1, the closer the directions representing the two vectors are; the closer to-1, the more opposite their direction; approaching 0, meaning that the two vectors are nearly orthogonal, may represent a relative difference in the direction of the two vectors. Thus, the similarity calculation mode can accurately measure the similarity between prescription information and each treatment scheme.

Based on this, after the matching result is obtained, the cpu 201 can confirm the signal parameters according to the matching result. Specifically, if the matching result includes a treatment plan, taking the parameters in the treatment plan, namely the waveform parameters, as signal parameters; if the matching result does not contain a treatment scheme, the disease corresponding to the disease is indicated, no feasible treatment method is proved at present, or the corresponding treatment scheme is not recorded in the database. In this embodiment, a control interface may be displayed to the user through the external control device, so that the user invokes the stimulation waveform library to edit the stimulation signal through the control interface. Specifically, the stimulus waveform library includes a plurality of basic stimulus waveforms, for example: the regulating interface can be a waveform editing interface, and a user can call any one or more waveforms in the stimulation waveform library in the interface to adjust parameters such as amplitude, period, phase and the like, and operations such as superposition, splicing and the like of the waveforms. The central processor 201 may receive the editing parameters of the user in the regulation interface, and then take the editing parameters as signal parameters.

In this embodiment, after determining the signal parameters, the central processor 201 may determine the stimulation mode according to the signal parameters, and then send the signal parameters to the piezoelectric stimulation module 301, the high-voltage stimulation module 401, or the regulation module 501 according to the stimulation mode. Specifically, the signal parameters can be used to determine whether the stimulation signal defined by the signal parameters is a low-voltage stimulation signal, a high-voltage stimulation signal, or both. When the stimulation signal defined by the signal parameters is a low-voltage stimulation signal, the central processor 201 sends the signal parameters to the low-voltage stimulation module 301; when the stimulation signal defined by the signal parameters is a high-voltage stimulation signal, the central processor 201 sends the signal parameters to the high-voltage stimulation module 401; when the stimulation signals defined by the signal parameters are the low-voltage stimulation signals and the high-voltage stimulation signals, the central processor 201 sends the signal parameters to the regulation module 501.

In this embodiment, the highest output voltage of the low-voltage electrical stimulation is 100V, and for example, the output voltage range of the low-voltage electrical stimulation may be: 0V-100V, commonly used for electrical stimulation treatment of the head, for example: and (3) electrically stimulating scenes such as electrooculogram, electroencephalogram, and aural vagus. Specifically, the low-voltage stimulation module 301 is connected to the first output electrode, and the low-voltage stimulation module 301 is configured to generate a corresponding low-voltage stimulation according to the signal parameter or the low-voltage signal after receiving the signal parameter or the low-voltage signal, and output the low-voltage stimulation based on the first output electrode. The first output electrode is used for being attached to a patient to realize electrical stimulation treatment. The low voltage signal is a parameter obtained after the control module 501 analyzes the received signal parameter, which will be described in detail later.

Illustratively, as shown in fig. 3, the piezoelectric stimulation module 301 includes: a stimulus signal generator 302, a first constant current source 303, a current equalizer 304 and a time-sharing switch selection component 305. One end of the stimulus signal generator 302 is connected to the central processor 201, and the stimulus signal generator 302 is configured to receive signal parameters sent by the central processor 201 and generate a corresponding low-voltage waveform signal based on the signal parameters. The other end of the stimulation signal generator 302 is connected to one end of a first constant current source 303, and the first constant current source 303 is configured to generate a corresponding low-voltage stimulation signal according to the low-voltage waveform signal. The other end of the first constant current source 303 is connected to one end of the current equalizer 304, and the current equalizer 304 is used for determining the number of output lines according to signal parameters and equalizing the current in the output lines. The other end of the current equalizer 304 is connected to one end of a time-sharing switch selection component 305, the time-sharing switch selection component 305 includes a processor 306 and a plurality of first output ports 307, the processor 306 is configured to determine an output time, an output duration and an output signal of each of the plurality of first output ports 307 according to a signal parameter, and the plurality of first output ports 307 is configured to output a low voltage stimulation signal.

In the present embodiment, in the context of piezoelectric stimulation, there is a need for treatment that simultaneously or cyclically electrically stimulates a plurality of different sites. For example, in a periocular electrical stimulation therapy method, four points around the eye need to be stimulated in a cyclic manner, and waveforms of the stimulation are different from one point to another. In this case, the signal parameters transmitted by the cpu 201 are the signal modulation parameters of the 4 waveforms, the stimulation time and stimulation sequence of the electrical stimulation corresponding to each waveform, and the cycle period. Based on this, first, the stimulation signal generator 302 generates 4 types of corresponding low-voltage waveform signals based on the signal modulation parameters of the 4 types of waveforms, and then generates the corresponding 4 types of low-voltage stimulation signals by the first constant current source 303. Current equalizer 304 then equalizes the current in 4 ways when it determines that 4 outputs are needed. Finally, the processor 306 in the time-sharing switch selection component 305 determines that the 4 first output ports output the 4 low-voltage stimulation signals, and determines the output time, the output duration and the output signal of each first output port according to the stimulation time and the stimulation sequence of the electrical stimulation corresponding to each waveform and the cycle period, so as to complete the cycle output of the 4 low-voltage stimulation signals.

In this embodiment, the highest output voltage of the high-voltage electrical stimulation is 350V, and for example, the output voltage range of the high-voltage electrical stimulation may be: 100V-350V, commonly used for electrical stimulation therapy of the torso, for example: aiming at the scene of electrical stimulation of percutaneous nerves, spinal cord, muscles and the like. Specifically, the high-voltage stimulation module 401 is connected to the second output electrode, where the high-voltage stimulation module 401 is configured to generate corresponding high-voltage stimulation according to the signal parameter or the high-voltage signal after receiving the signal parameter or the high-voltage signal, and output the high-voltage stimulation based on the second output electrode. The second output electrode is used for being attached to the patient to realize electrical stimulation treatment. The high voltage signal is a parameter obtained after the control module 501 analyzes the received signal parameter, which will be described in detail later.

Illustratively, as shown in FIG. 3, the high voltage stimulation module 401 includes: a current controller 402, a pulse signal generator 403, a second constant current source 404, and an isolated current transducer 405. One end of the current controller 402 is connected to the central processing unit 201, and the current controller 402 is configured to receive signal parameters sent by the central processing unit 201, and regulate and control the current according to the signal parameters. The other end of the current controller 402 is connected to one end of a pulse signal generator 403, and the pulse signal generator 403 is configured to generate a high-voltage waveform signal according to a signal parameter. The other end of the pulse signal generator 403 is connected to one end of a second constant current source 404, and the second constant current source 404 is configured to generate a corresponding high-voltage stimulation signal according to the high-voltage waveform signal. The other end of the second constant current source 404 is connected to an isolated current transducer 405, and the isolated current transducer 405 includes an isolator 406 and a plurality of second output ports 407, the isolator 406 being used to isolate the second constant current source 404 from the subject, the plurality of second output ports 407 being used to output high voltage stimulation signals.

In this embodiment, in some treatments, the head and the trunk are required to be simultaneously electrically stimulated, for example, when the electrical stimulation treatment is performed for the cases of essential tremors, dyskinesias, etc., the electrical stimulation signals are required to be simultaneously output with the high-voltage electrical stimulation signals, so that synchronous stimulation of the head and the trunk is realized. Specifically, the synchronous generation and output of the high-voltage electrical stimulation signal and the low-voltage electrical stimulation signal may be achieved by the regulation module 501.

In this embodiment, when the stimulation signals defined by the signal parameters are low-voltage stimulation signals and high-voltage stimulation signals, the signal parameters are sent to the regulation module 501. The regulation module 501 is connected to the low-voltage stimulation module 301 and the high-voltage stimulation module 401, respectively, so that after receiving the signal parameters, the regulation module 501 is configured to analyze the signal parameters, separate the definition of the low-voltage stimulation signal from the separation of the high-voltage stimulation signal, obtain the low-voltage parameters and the high-voltage parameters, send the low-voltage parameters to the low-voltage stimulation module, and send the high-voltage parameters to the high-voltage stimulation module.

Illustratively, as shown in FIG. 3, the regulatory module 501 includes: a coupling assembly 502, a programmable variable voltage power supply assembly 503, and an electrode contact quality acquisition assembly 504. The coupling component 502 is respectively connected to the central processor 201, the stimulation signal generator 302 and the pulse signal generator 403, and the coupling component 502 is configured to receive signal parameters from the central processor 201, parse the signal parameters, and send low-voltage parameters obtained by parsing to the stimulation signal generator 302, so that the stimulation signal generator 302 generates a corresponding low-voltage waveform signal based on the low-voltage parameters, and then further generates a low-voltage stimulation signal under the action of the first constant current source 303. Meanwhile, the high-voltage parameters obtained through analysis are sent to the pulse signal generator 403, so that the pulse signal generator 403 generates corresponding high-voltage waveform signals based on the high-voltage parameters, and then further generates high-voltage stimulation signals under the action of the second constant current source 404, and synchronous generation and output of the low-voltage stimulation signals and the high-voltage stimulation signals are realized.

In this embodiment, the programmable variable voltage power supply module 503 is connected to the central processing unit 201, the first constant current source 303 and the second constant current source 404, and the programmable variable voltage power supply module 503 is configured to receive a voltage adjustment parameter from the central processing unit 201 and send the voltage adjustment parameter to the first constant current source 303 and/or the second constant current source 404, so as to regulate and control an output voltage of the first constant current source and/or the second constant current source. Specifically, the program-controlled variable voltage power supply component 503 can adjust the voltage within the voltage range allowed by the treatment according to the current fed back, so that the overall voltage is reduced as much as possible while the current meets the requirement, and the energy-saving effect is realized. The electrode contact quality acquisition component 504 is respectively connected with the central processing unit 201, the first constant current source 303 and the second constant current source 404, and the electrode contact quality acquisition component 504 is used for acquiring the voltage of the first constant current source 303 and/or the second constant current source 404 and sending the voltage of the first constant current source 303 and/or the second constant current source 404 to the central processing unit 201 so that the central processing unit determines the contact quality between the first output electrode and/or the second output electrode and the tested person according to the voltage of the first constant current source 303 and/or the second constant current source 404. Specifically, the worse the contact quality, the higher the resistance, and in order to ensure the effect of the electrical stimulation, the device can gradually strengthen the output voltage, and then cause accidents such as burn. Therefore, the voltage of the constant current source is monitored in real time through the electrode contact quality acquisition assembly 504 to determine the contact quality of the electrode with the human body, so as to prevent the occurrence of the above-mentioned accidents and ensure the effect of the treatment.

In this embodiment, the device may further include an alarm component, where the alarm component is connected to the central processor 201, and after receiving an alarm signal sent by the central processor, the alarm component may trigger a corresponding audible and visual alarm according to the alarm signal. For example, when the electrode contact quality acquisition module 504 detects a voltage abnormality of the constant current source, a contact quality abnormality signal may be sent to the central processor 201, and the central processor 201 may send the contact quality abnormality signal to the alarm module. After receiving the contact quality abnormal signal, the alarm component can be matched with an audible and visual alarm rule corresponding to the signal to carry out audible and visual alarm.

In summary, in the electrical stimulation generating device provided by the present invention, the signal parameters of the corresponding electrical stimulation waveforms are determined by receiving external information, such as prescription information of the patient to be treated. The signal parameters are then sent to the corresponding signal generation modules, namely: the high-voltage stimulation module is used for generating corresponding electric stimulation and outputting the generated electric stimulation. Therefore, free editing and definition of waveforms are realized, and then waveform stimulation required by all diseases is generated through one device, so that the cost is greatly reduced.

Referring to fig. 4, fig. 4 is a schematic flow chart of an electrical stimulation generating method according to an embodiment of the present application, and the method may be applied to the electrical stimulation generating device described above. As shown in fig. 4, the electrical stimulation generation method includes, but is not limited to, the following steps:

s601: the central processing unit receives external information for processing and sends corresponding signal parameters to the piezoelectric stimulation module, the high-voltage stimulation module or the regulation and control module according to the processing result.

In this embodiment, the external information includes prescription information, based on which the central processor may perform matching in a treatment prescription library according to the prescription information to obtain a matching result, where the treatment prescription library includes a plurality of treatment schemes. If the matching result contains the treatment scheme, taking the parameters in the treatment scheme as signal parameters; and if the matching result does not contain the treatment scheme, displaying a regulation interface to a user so that the user can call a stimulation waveform library to edit the stimulation signals through the regulation interface, wherein the stimulation waveform library comprises a plurality of basic stimulation waveforms. And then receiving editing parameters of the user in the regulation interface, taking the editing parameters as signal parameters, and determining a stimulation mode according to the signal parameters. And finally, sending the signal parameters to a low-voltage electric stimulation module, a high-voltage electric stimulation module or a regulation and control module according to the stimulation mode.

S602: when the low-voltage stimulation module receives the signal parameters, the low-voltage stimulation module generates corresponding low-voltage stimulation signals according to the signal parameters and outputs the signals.

In this embodiment, the highest output voltage of the piezoelectric stimulus is 100V.

S603: when the high-voltage stimulation module receives the signal parameters, the high-voltage stimulation module generates corresponding high-voltage stimulation signals according to the signal parameters and outputs the signals.

In this embodiment, the highest output voltage of the high-voltage electrical stimulation is 350V.

S604: when the regulation and control module receives the signal parameters, the regulation and control module analyzes the signal parameters to obtain low-voltage parameters and high-voltage parameters, the low-voltage parameters are sent to the low-voltage stimulation module, the high-voltage parameters are sent to the high-voltage stimulation module, so that the low-voltage stimulation module generates corresponding low-voltage stimulation signals according to the low-voltage parameters, and the high-voltage stimulation module generates corresponding high-voltage stimulation signals according to the high-voltage parameters to synchronously output the corresponding high-voltage stimulation signals.

The specific implementation process of step S601 to step S604 may refer to specific functions of the central processing unit, the piezoelectric stimulation module, the high-voltage stimulation module, and the regulation module, which are not described herein.

Referring to fig. 5, fig. 5 is a schematic structural diagram of an electronic device according to an embodiment of the present application. As shown in fig. 5, the electronic device 700 includes a transceiver 701, a processing unit 702, and a memory 703. Which are connected by a bus 704. The memory 703 is used for storing computer programs and data, and the data stored in the memory 703 can be transferred to the processing unit 702.

The processing unit 702 is configured to read the computer program in the storage 703 to perform the following operations:

receiving external information for processing, and sending corresponding signal parameters to a low-voltage stimulation module, a high-voltage stimulation module or a regulation and control module according to a processing result;

when the low-voltage stimulation module receives the signal parameters, the low-voltage stimulation module generates corresponding low-voltage stimulation signals according to the signal parameters and outputs the low-voltage stimulation signals;

when the high-voltage stimulation module receives the signal parameters, the high-voltage stimulation module generates corresponding high-voltage stimulation signals according to the signal parameters and outputs the signals;

The external information includes prescription information, based on which the external information is received and processed, and the corresponding signal parameters are sent to the low-voltage stimulation module, the high-voltage stimulation module or the regulation module according to the processing result, where the processing unit 702 is specifically configured to execute the following steps:

determining a stimulation mode according to the signal parameters;

In the embodiment of the present invention, the processing unit 702 is specifically configured to perform the following steps in performing matching in the treatment prescription library according to the prescription information to obtain a matching result:

In an embodiment of the present invention, a piezoelectric stimulation module includes:

wherein,

In an embodiment of the invention, the high voltage stimulation module comprises:

wherein,

In an embodiment of the invention, the regulation module comprises:

wherein,

In an embodiment of the present invention, the apparatus further comprises:

In an embodiment of the present invention, the output voltage of the high voltage electrical stimulation ranges from 0V to 100V, and the output voltage of the high voltage electrical stimulation ranges from 100V to 350V.

It should be understood that the electrical stimulation generating device in the present application may include a smart Phone (such as an Android mobile Phone, an iOS mobile Phone, a Windows Phone mobile Phone, etc.), a tablet computer, a palm computer, a notebook computer, a mobile internet device MID (Mobile Internet Devices, abbreviated as MID), a robot, a wearable device, etc. The above-described electrical stimulation generating devices are merely examples and are not exhaustive and include, but are not limited to, the above-described electrical stimulation generating devices. In practical application, the above-mentioned electric stimulation generating device may further include: intelligent vehicle terminals, computer devices, etc.

From the above description of embodiments, it will be apparent to those skilled in the art that the present invention may be implemented in software in combination with a hardware platform. With such understanding, all or part of the technical solution of the present invention contributing to the background art may be embodied in the form of a software product, which may be stored in a storage medium, such as ROM/RAM, a magnetic disk, an optical disk, etc., including several instructions for causing a computer device (which may be a personal computer, a server, or a network device, etc.) to perform the methods described in the various embodiments or parts of the embodiments of the present invention.

Accordingly, the present application also provides a computer-readable storage medium storing a computer program that is executed by a processor to implement some or all of the steps of any one of the electrical stimulation generation methods described in the above method embodiments. For example, the storage medium may include a hard disk, a floppy disk, an optical disk, a magnetic tape, a magnetic disk, a flash memory, etc.

Embodiments of the present application also provide a computer program product comprising a non-transitory computer-readable storage medium storing a computer program operable to cause a computer to perform some or all of the steps of any one of the electrical stimulation generation methods described in the method embodiments above.

It should be noted that, for simplicity of description, the foregoing method embodiments are all expressed as a series of action combinations, but it should be understood by those skilled in the art that the present application is not limited by the order of actions described, as some steps may be performed in other order or simultaneously according to the present application. Further, those skilled in the art will also appreciate that the embodiments described in the specification are all alternative embodiments, and that the acts and modules referred to are not necessarily required in the present application.

In the foregoing embodiments, the descriptions of the embodiments are focused on, and for those portions of one embodiment that are not described in detail, reference may be made to the related descriptions of other embodiments.

In the several embodiments provided in this application, it should be understood that the disclosed apparatus may be implemented in other manners. For example, the apparatus embodiments described above are merely illustrative, such as the division of the units, merely a logical function division, and there may be additional divisions when actually implemented, such as multiple units or components may be combined or integrated into another system, or some features may be omitted or not performed. Alternatively, the coupling or direct coupling or communication connection shown or discussed with each other may be an indirect coupling or communication connection via some interfaces, devices or units, or may be in electrical or other forms.

The units described as separate units may or may not be physically separate, and units shown as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the embodiment.

In addition, each functional unit in each embodiment of the present application may be integrated into one processing unit, each unit may exist alone physically, or two or more units may be integrated into one unit. The integrated units described above may be implemented either in hardware or in software program modules.

The integrated units, if implemented in the form of software program modules, may be stored in a computer-readable memory for sale or use as a stand-alone product. Based on such understanding, the technical solution of the present application may be embodied in essence or a part contributing to the prior art or all or part of the technical solution in the form of a software product stored in a memory, including several instructions for causing a computer device (which may be a personal computer, a server or a network device, etc.) to perform all or part of the steps of the method described in the embodiments of the present application. And the aforementioned memory includes: a U-disk, a Read-Only Memory (ROM), a random access Memory (RAM, random Access Memory), a removable hard disk, a magnetic disk, or an optical disk, or other various media capable of storing program codes.

Those of ordinary skill in the art will appreciate that all or a portion of the steps in the various methods of the above embodiments may be implemented by a program that instructs associated hardware, and the program may be stored in a computer readable memory, and the memory may include: flash disk, read-Only Memory (ROM), random access Memory (Random Access Memory, RAM), magnetic disk or optical disk.

The foregoing has outlined rather broadly the more detailed description of the embodiments herein, and the detailed description of the principles and embodiments herein has been presented in terms of specific examples only to assist in the understanding of the methods and concepts of the present application; meanwhile, as those skilled in the art will have modifications in the specific embodiments and application scope in accordance with the ideas of the present application, the present description should not be construed as limiting the present application in view of the above.

Claims

1. An electrical stimulation generating device, the device comprising:

the device comprises a central processing unit, a low-voltage stimulation module, a high-voltage stimulation module and a regulation and control module;

wherein,

the central processing unit is respectively connected with the low-voltage electric stimulation module, the high-voltage electric stimulation module and the regulation and control module, wherein the central processing unit is used for receiving external information for processing and sending corresponding signal parameters to the low-voltage electric stimulation module, the high-voltage electric stimulation module or the regulation and control module according to a processing result, when the signal parameters are low-voltage parameters, the central processing unit sends the signal parameters to the low-voltage electric stimulation module, when the signal parameters are high-voltage parameters, the central processing unit sends the signal parameters to the high-voltage electric stimulation module, and when the signal parameters comprise the low-voltage parameters and the high-voltage parameters, the central processing unit sends the signal parameters to the regulation and control module;

The regulation and control module is respectively connected with the low-voltage electric stimulation module and the high-voltage electric stimulation module, wherein the regulation and control module is used for analyzing the signal parameters after receiving the signal parameters to obtain the low-voltage parameters and the high-voltage parameters, sending the low-voltage parameters to the low-voltage electric stimulation module and sending the high-voltage parameters to the high-voltage electric stimulation module;

the low-voltage stimulation module is connected with a first output electrode, wherein the low-voltage stimulation module is used for generating corresponding low-voltage stimulation according to the signal parameter or the low-voltage parameter after receiving the signal parameter or the low-voltage parameter, and outputting the low-voltage stimulation based on the first output electrode, and the highest output voltage of the low-voltage stimulation is 100V;

the high-voltage electric stimulation module is connected with a second output electrode, wherein the high-voltage electric stimulation module is used for generating corresponding high-voltage electric stimulation according to the signal parameter or the high-voltage parameter after receiving the signal parameter or the high-voltage parameter, and outputting the high-voltage electric stimulation based on the second output electrode, and the highest output voltage of the high-voltage electric stimulation is 350V;

The central processing unit is specifically configured to:

matching is carried out in a treatment prescription library according to the prescription information to obtain a matching result, wherein the treatment prescription library comprises a plurality of treatment schemes;

if the matching result contains a treatment scheme, taking parameters in the treatment scheme as the signal parameters;

if the matching result does not contain a treatment scheme, a regulation interface is displayed for a user, so that the user invokes a stimulation waveform library to edit stimulation signals through the regulation interface, wherein the stimulation waveform library comprises a plurality of basic stimulation waveforms;

receiving editing parameters of the user in the regulation interface, and taking the editing parameters as the signal parameters;

determining a stimulation pattern from the signal parameters;

and sending the signal parameters to the low-voltage stimulation module, the high-voltage electrical stimulation module or the regulation and control module according to the stimulation mode.

2. The device according to claim 1, wherein, in terms of matching in the treatment prescription library according to the prescription information, the central processing unit is specifically configured to:

performing feature extraction on the diagnosis information and the disease information in the prescription information to obtain prescription feature vectors;

calculating a module of the prescription feature vector, and calculating a module of a treatment feature vector corresponding to each treatment scheme in a plurality of treatment schemes in the treatment prescription library;

taking the quotient of the inner product value and the product value as the similarity of the prescription information and each treatment plan;

and determining whether the similarity greater than a preset threshold exists in the plurality of similarities, if so, enabling a treatment scheme corresponding to the maximum value in the plurality of similarities to serve as the matching result, and if not, enabling the matching result to be null.

3. The apparatus of claim 1 or 2, wherein the low voltage electrical stimulation module comprises:

wherein,

the other end of the stimulation signal generator is connected with one end of the first constant current source, and the first constant current source is used for generating a corresponding low-voltage stimulation signal according to the low-voltage waveform signal;

the other end of the first constant current source is connected with one end of the current equalizer, and the current equalizer is used for determining the number of output lines according to the signal parameters and equalizing the current in the output lines;

the other end of the current equalizer is connected with one end of the time-sharing switch selection assembly, the time-sharing switch selection assembly comprises a processor and a plurality of first output ports, the processor is used for determining output time, output duration and output signals of each of the plurality of first output ports according to the signal parameters, and the plurality of first output ports are used for outputting the low-voltage stimulation signals.

4. The apparatus of claim 3, wherein the high voltage electrical stimulation module comprises:

wherein,

the other end of the current controller is connected with one end of the pulse signal generator, and the pulse signal generator is used for generating a high-voltage waveform signal according to the signal parameters;

the other end of the pulse signal generator is connected with one end of the second constant current source, and the second constant current source is used for generating a corresponding high-voltage stimulation signal according to the high-voltage waveform signal;

the other end of the second constant current source is connected with the isolation current transmitter, the isolation current transmitter comprises an isolator and a plurality of second output ports, the isolator is used for isolating the second constant current source and a tested person, and the plurality of second output ports are used for outputting the high-voltage stimulation signals.

5. The apparatus of claim 4, wherein the regulation module comprises:

wherein,

the coupling component is respectively connected with the central processing unit, the stimulation signal generator and the pulse signal generator, and is used for receiving the signal parameters from the central processing unit, analyzing the signal parameters, sending the analyzed low-voltage parameters to the stimulation signal generator, and sending the analyzed high-voltage parameters to the pulse signal generator;

the electrode contact quality acquisition component is respectively connected with the central processing unit, the first constant current source and the second constant current source, and is used for acquiring the voltage of the first constant current source and/or the second constant current source and sending the voltage of the first constant current source and/or the voltage of the second constant current source to the central processing unit so that the central processing unit can determine the contact quality between the first output electrode and/or the second output electrode and the tested person according to the voltage of the first constant current source and/or the voltage of the second constant current source.

6. The apparatus of claim 5, wherein the apparatus further comprises:

7. The apparatus of claim 1, wherein the device comprises a plurality of sensors,

the output voltage of the piezoelectric stimulus is in the range of 0V-100V;

the output voltage of the high-voltage electric stimulation is in the range of 100V-350V.

8. An electrical stimulation generation method, characterized in that the method is applied to an electrical stimulation generation device comprising: the device comprises a central processing unit, a low-voltage stimulation module, a high-voltage stimulation module and a regulation and control module, wherein the method comprises the following steps:

the central processing unit receives external information for processing and sends corresponding signal parameters to the low-voltage electric stimulation module, the high-voltage electric stimulation module or the regulation and control module according to a processing result, wherein when the signal parameters are low-voltage parameters, the central processing unit sends the signal parameters to the low-voltage electric stimulation module, when the signal parameters are high-voltage parameters, the central processing unit sends the signal parameters to the high-voltage electric stimulation module, and when the signal parameters comprise the low-voltage parameters and the high-voltage parameters, the central processing unit sends the signal parameters to the regulation and control module;

when the high-voltage electric stimulation module receives the signal parameters, the high-voltage electric stimulation module generates corresponding high-voltage electric stimulation signals according to the signal parameters to output, and the highest output voltage of the high-voltage electric stimulation is 350V;

when the regulation and control module receives the signal parameters, the regulation and control module analyzes the signal parameters to obtain the low-voltage parameters and the high-voltage parameters, the low-voltage parameters are sent to the low-voltage stimulation module, the high-voltage parameters are sent to the high-voltage electrical stimulation module, so that the low-voltage electrical stimulation module generates corresponding low-voltage electrical stimulation signals according to the low-voltage parameters, and the high-voltage electrical stimulation module generates corresponding high-voltage electrical stimulation signals according to the high-voltage parameters to synchronously output the corresponding high-voltage electrical stimulation signals;

the central processing unit is specifically configured to:

determining a stimulation pattern from the signal parameters;

9. An electronic device comprising a processor, a memory, a communication interface, and one or more programs, wherein the one or more programs are stored in the memory and configured to be executed by the processor, the one or more programs comprising instructions for performing the steps in the method of claim 8.

10. A computer readable storage medium storing a computer program for execution by a processor to implement the method of claim 8.