CN116898468A

CN116898468A - Dynamic quality control method of D-SPECT system

Info

Publication number: CN116898468A
Application number: CN202310862601.2A
Authority: CN
Inventors: 尤尔; 马治福; 杨志山; 张卓东
Original assignee: Shanghai Guangmai Medical Technology Co ltd
Current assignee: Shanghai Guangmai Medical Technology Co ltd
Priority date: 2023-07-14
Filing date: 2023-07-14
Publication date: 2023-10-20

Abstract

The application provides a dynamic quality control method of a D-SPECT system, which comprises the following steps: a plurality of detection units acquire a plurality of scanning data of the radioactive source simulation nuclide in a first duration; dividing the plurality of scanning data into a plurality of first sub-data sets corresponding to different time points according to the time information; each scanning data is divided into a second sub-data set corresponding to different positions according to the space information; obtaining uniformity and/or resolution of the scan data from the plurality of first sub-data sets; obtaining a plurality of time activity curves from the plurality of second sub-data sets; the dynamic scan quality of the D-SPECT system is determined based on the uniformity of the scan data, the resolution of the scan data, and/or the plurality of time activity curves. According to the quality control method, the dynamic scanning quality of the system is evaluated through the scanning data of the D-SPECT system on the radioactive source simulated nuclide, and whether the D-SPECT system needs further adjustment or meets the requirement on target data can be determined according to the dynamic scanning quality evaluation result.

Description

Dynamic quality control method of D-SPECT system

Technical Field

The application relates to the technical field of medical imaging, in particular to a dynamic quality control method of a D-SPECT system.

Background

The conventional quality control project of the conventional SPECT mainly comprises inherent spatial resolution, uniformity, planar sensitivity, inherent spatial linearity, rotation center drift and the like, wherein the inherent spatial resolution, the inherent spatial linearity, the rotation center drift are generally stable, but the uniformity, the energy peak and the resolution are easy to change, the conventional SPECT is subjected to quality control by using 99 technetium marking liquid medicine sources with different shapes and different distances from a detector, collimators with different shapes are also required to be replaced, the quality control time is long, the process is complicated, the radiation dose of a quality control operator is relatively high, special quality control cannot be performed for the dynamic acquisition of the heart, the conventional quality control cannot be performed only before the dynamic acquisition of the heart, the performance state before the dynamic acquisition of the heart can not be well confirmed, and the factors seriously affect the quality control scanning of the performance state before the dynamic acquisition of the heart of the SPECT, so that the whole process of the dynamic acquisition of the heart is seriously affected, and the interpretation of clinical image results is caused.

The heart is vital to the human body, and is one of the most important organs of the human body, and the heart pumps blood through blood vessels to provide necessary energy for all activities of the human body, and in the process, the heart itself is also required to supply blood, for example, if the heart muscle itself and/or coronary arteries supplying the heart muscle are diseased, the blood supply function of the heart is seriously affected, and even the human life is endangered. Among them, the heart disease caused by coronary artery stenosis and the heart disease caused by heart microvascular lesion are the most fatal, and the two diseases can cause serious defect of myocardial blood supply, thus serious heart adverse events occur, and life is endangered. Therefore, monitoring the effect of preventing and accurately diagnosing coronary stenosis on cardiac blood supply and whether there are microvascular lesions and the extent of the effect of lesions on myocardial blood supply is of paramount importance.

Currently, the most advanced monitoring, prevention and diagnosis means mainly include positron emission computed tomography (positron emission tomography, PET) and SPECT to measure myocardial blood flow reserve (Myocardial Flow Reserve, MFR), also called coronary blood flow reserve (Coronary Flow Reserve, CFR), wherein radionuclides (such as 18F labeled oxygen water) required for PET are produced by using cyclotrons, which have high cost, short half-life, difficult transportation and storage, and too high cost of PET itself. In contrast, SPECT uses 99 technetium labeled drugs with a longer half-life, both at cost and for transport and storage, far superior to the nuclides required for PET, and SPECT measured CFR values have a high correlation and consistency with PET as reported in the relevant literature. Therefore, the use of SPECT for CFR measurement is one of the most recommended noninvasive examination and diagnosis means in the fields of cardiovascular and nuclear medicine at home and abroad at present.

In order to ensure the stability of the performance and the accuracy of the image result during the dynamic acquisition of the SPECT on the heart, shorten the time for acquiring the dynamic quality control of the heart and improve the efficiency of the dynamic quality control of the heart, a concise, rapid and higher-result-accuracy SPECT dynamic quality control method is needed.

It should be noted that the information disclosed in the foregoing background section is only for enhancement of understanding of the background of the application and thus may include information that does not form the prior art that is already known to those of skill in the art.

Disclosure of Invention

Aiming at the problems in the prior art, the application aims to provide a dynamic quality control method of a D-SPECT system, wherein the dynamic scanning quality of the system is evaluated through the scanning data of the D-SPECT system on the radionuclide-simulated radionuclides, and whether the D-SPECT system needs further adjustment or meets the requirement on target data can be determined according to the dynamic scanning quality evaluation result.

The embodiment of the application provides a dynamic quality control method of a D-SPECT system, which comprises an L-shaped tomographic imaging probe provided with a plurality of detection units, a radioactive source simulated nuclide, an adjustable clamp and a processing unit;

one end of the adjustable clamp is connected with the L-shaped tomography probe;

the other end of the adjustable clamp is connected with the radioactive source simulation nuclide;

the processing unit is connected with the L-shaped tomography probe and receives photon scanning data of the L-shaped tomography probe on the radioactive source simulation nuclide;

the quality control method comprises the following steps:

the detection units acquire a plurality of scanning data of the radioactive source simulation nuclide in a first duration, wherein each scanning data respectively comprises time information and space information;

dividing the scanning data into a plurality of first sub-data sets corresponding to different time points according to time information, and/or dividing each scanning data into a second sub-data set corresponding to different positions according to space information;

obtaining uniformity and/or resolution of the scan data from a plurality of the first sub-data sets and/or obtaining a plurality of time activity curves from a plurality of the second sub-data sets;

the dynamic scan quality of the D-SPECT system is determined from the uniformity of the scan data, the resolution of the scan data, and/or a plurality of the time activity curves.

According to some examples of the application, the distance of the radionuclide from the central location at the break angle of the L-shaped tomographic imaging probe is adjustable by the adjustable clamp.

According to some examples of the present application, before the plurality of probes acquire the plurality of scan data of the radiation source simulation nuclide for the first time period, the quality control method further includes the steps of:

and adjusting the distance between the radioactive source simulation nuclide and the central position of the folded angle of the L-shaped tomography probe according to the application parameters.

According to some examples of the application, the application parameters are determined from a target scan object.

According to some examples of the application, the distance of the radioactive source simulation nuclide from the central position at the folded angle of the distance of the L-shaped tomographic imaging probe ranges from 10cm to 20cm.

According to some examples of the present application, after the step of obtaining a plurality of time activity curves from a plurality of the second sub-data sets, the method further includes:

and obtaining the attenuation rate according to the time activity curve.

According to some examples of the application, the obtaining the uniformity and/or resolution of the scan data from a plurality of the first sub-data sets comprises the steps of:

obtaining a panoramic view of the corresponding time point of the radionuclide for the radiation source simulation according to the first sub-data set of each time point;

and obtaining the uniformity and/or resolution of the scanning data of the corresponding time points according to the panoramic image of each time point.

According to some examples of the application, the determining the dynamic scan quality of the D-SPECT system from the uniformity of the scan data, the resolution of the scan data, and/or the plurality of the time activity curves includes the steps of:

judging whether the uniformity is larger than a first threshold value;

judging whether the resolution is larger than a second threshold value; and/or

Judging whether the absolute value of the difference value between the attenuation rate and the attenuation rate of the radioactive source simulation nuclide is larger than a third threshold value;

if the above condition or conditions are met, then the dynamic scan quality of the D-SPECT system is deemed to not meet the set requirements.

According to some examples of the application, the radioactive source of the radioactive source-mimicking nuclear species is Co-57 and the first duration is 390 seconds.

The dynamic quality control method of the D-SPECT system provided by the application can be used for determining whether the D-SPECT system needs further adjustment or meets the requirement on target data according to the dynamic scanning quality evaluation result by evaluating the dynamic scanning quality of the system through the scanning data of the radioactive source simulated nuclide, and the method is simple, quick and effective in completing the quality control before dynamic scanning, thereby bringing great help to the accuracy of clinical diagnosis results.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the application and together with the description, serve to explain the principles of the application and, together with the description, further features, objects and advantages of the application, will become apparent from a reading of the following detailed description of non-limiting embodiments, taken in conjunction with the accompanying drawings. It is evident that the drawings in the following description are only some embodiments of the present application and that other drawings may be obtained from these drawings without inventive effort for a person of ordinary skill in the art. Furthermore, the drawings are merely schematic illustrations of the present disclosure and are not necessarily drawn to scale. The same reference numerals in the drawings denote the same or similar parts, and thus a repetitive description thereof will be omitted. Some of the block diagrams shown in the figures are functional entities and do not necessarily correspond to physically or logically separate entities.

FIG. 1 is a schematic diagram of a D-SPECT system in accordance with an embodiment of the present application;

FIG. 2 is a flow chart of a dynamic quality control method of a D-SPECT system in accordance with an embodiment of the present application;

FIG. 3 is radionuclide-simulated scan data for a D-SPECT system according to an embodiment of the present application; and

FIG. 4 is cardiac scan data of a D-SPECT system following the dynamic quality control method of the present application.

Detailed Description

Example embodiments will now be described more fully with reference to the accompanying drawings. However, the exemplary embodiments may be embodied in many forms and should not be construed as limited to the examples set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of the example embodiments to those skilled in the art. The described features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.

In the description of the present specification, reference to the terms "one embodiment," "some embodiments," "examples," "particular examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present specification. Furthermore, the particular features, structures, materials, or characteristics may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, the different embodiments or examples and the features of the different embodiments or examples presented in this specification may be combined and combined by those skilled in the art without contradiction.

Throughout the specification, when a device is said to be "connected" to another device, this includes not only the case of "direct connection" but also the case of "indirect connection" with other elements interposed therebetween. Although the terms first, second, etc. may be used herein to connote various elements in some instances, the elements should not be limited by the terms. These terms are only used to distinguish one element from another element. For example, a first interface, a second interface, etc. Furthermore, as used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context indicates otherwise. It will be further understood that the terms "comprises," "comprising," "includes," and/or "including" specify the presence of stated features, steps, operations, elements, components, items, categories, and/or groups, but do not preclude the presence, presence or addition of one or more other features, steps, operations, elements, components, items, categories, and/or groups. The terms "or" and/or "as used herein are to be construed as inclusive, or meaning any one or any combination. Thus, "A, B or C" or "A, B and/or C" means "any of the following: a, A is as follows; b, a step of preparing a composite material; c, performing operation; a and B; a and C; b and C; A. b and C). An exception to this definition will occur only when a combination of elements, functions, steps or operations are in some way inherently mutually exclusive.

Although not differently defined, including technical and scientific terms used herein, all terms have the same meaning as commonly understood by one of ordinary skill in the art to which this specification belongs. The term addition defined in the commonly used dictionary is interpreted as having a meaning conforming to the contents of the related art document and the current hint, so long as no definition is made, it is not interpreted as an ideal or very formulaic meaning too much.

In order to ensure the stability of performance and the accuracy of image results when a D-SPECT system dynamically collects a target scanning object such as a heart and the like, shorten the time for dynamically controlling and collecting the target scanning object and improve the efficiency of dynamic quality control scanning of the heart, the application provides a dynamic quality control method of the D-SPECT system, which comprises an L-shaped tomographic imaging probe provided with a plurality of detection units, radioactive source simulation nuclides, an adjustable clamp and a processing unit; one end of the adjustable clamp is connected with the L-shaped tomography probe; the other end of the adjustable clamp is connected with the radioactive source simulation nuclide; the processing unit is connected with the L-shaped tomography probe and receives photon scanning data of the L-shaped tomography probe on the radioactive source simulation nuclide; the quality control method comprises the following steps: the detection units acquire a plurality of scanning data of the radioactive source simulation nuclide in a first duration, wherein each scanning data respectively comprises time information and space information; dividing the scanning data into a plurality of first sub-data sets corresponding to different time points according to the time information; each scanning data is divided into a second sub-data set corresponding to different positions according to the space information; obtaining uniformity and/or resolution of the scan data from a plurality of the first sub-data sets; obtaining a plurality of time activity curves from a plurality of the second sub-data sets; the dynamic scan quality of the D-SPECT system is determined from the uniformity of the scan data, the resolution of the scan data, and/or a plurality of the time activity curves. According to the dynamic quality control method of the D-SPECT system, the dynamic scanning quality of the system is evaluated through the scanning data of the D-SPECT system on the radioactive source simulated nuclide, whether the D-SPECT system needs further adjustment or meets the requirement on target data can be determined according to the dynamic scanning quality evaluation result, the quality control before dynamic scanning is simply, quickly and effectively completed, and great help is brought to the accuracy of clinical diagnosis results.

The dynamic quality control method of the D-SPECT system of the present application is further described below with reference to the accompanying drawings and specific embodiments, and it is to be understood that the specific embodiments are not limiting of the scope of the present application.

FIG. 1 is a schematic diagram of a D-SPECT system including an L-shaped tomographic imaging probe 1 provided with a plurality of detection units 11, a radionuclide 2, an adjustable clamp 3, and a processing unit (not shown in the figures), according to an embodiment of the present application; one end of the adjustable clamp 3 is connected with the L-shaped tomography probe 1; the other end of the adjustable clamp 3 is connected with the radioactive source simulation nuclide 2; the processing unit is connected with the L-shaped tomography probe 1 and receives photon scanning data of the L-shaped tomography probe 1 on the radioactive source simulation nuclide 2. The number of detection units of the D-SPECT system is not limited. Of course, the D-SPECT system further comprises a base, a support and a three-section seat and the like for supporting the L-shaped tomography probe during scanning, and a collimator is further arranged in the L-shaped tomography probe and can be fixed, so that collimator replacement during quality control can be avoided.

Fig. 2 is a flowchart of a dynamic quality control method of a D-SPECT system according to an embodiment of the present application, specifically, the quality control method includes the following steps:

s10: the detection units acquire a plurality of scanning data of the radioactive source simulation nuclide in a first duration, wherein each scanning data respectively comprises time information and space information; in the step, the data of the radioactive source simulation nuclide collected by each detection unit in the L-shaped tomography probe of the D-SPECT system in the first time period is taken as scanning data, namely, the number of the detection units of the D-SPECT system determines the number of the obtained scanning data, each scanning data comprises time information and space information of the detection unit or the collected data, the time information is a time point corresponding to the number of the collected photons (the first time period can be divided into n time periods, the collected data in each time period is regarded as one frame of scanning data), the space information is position information corresponding to the number of the collected photons, and the collected data of the same time point of a plurality of detection units can construct a panoramic image of the radioactive source simulation nuclide which can be scanned by the L-shaped tomography probe.

The detector crystal and structure of the D-SPECT system are upgraded, wherein the detector crystal can adopt a tellurium-zinc-cadmium semiconductor, accordingly, the performance is greatly improved, the acquisition sensitivity is improved by 8-10 times, the energy resolution is improved by 2 times, the reconstruction resolution is improved by 2-4 times and the like compared with the traditional SPECT, more effective counts can be obtained in a shorter time, and the resolution of the reconstructed picture is higher.

In the quality control method, the radioactive source of the radioactive source simulated nuclide can adopt a special solid radioactive source with low activity and long half-life, such as Co-57, the half-life of the radioactive source simulated nuclide is 270 days, the radioactive source simulated nuclide can be linear, the length of the radioactive source simulated nuclide can cover the whole view field of the detector, and the radioactive source can simulate target scanning objects such as human hearts. In the process of collecting data, each detection unit in the L-shaped tomography probe faces to the radioactive source simulated nuclide and rotates around the self axis, each time the detection unit rotates by a certain angle, the detection unit can fully collect photons incident in a corresponding angle range (the radioactive source simulated nuclide emits photons of any angle in a 360-degree range) in each rotating position when the radioactive source simulated nuclide is scanned, the collecting time of each time, namely the first time length, is the same, and in the embodiment of the D-SPECT system serving as the special SPECT for the heart, the first time length is preferably 6 minutes and 30 seconds (390 seconds) so as to ensure that the D-SPECT system can simply, effectively and completely collect heart dynamic data.

Of course, in actual quality control detection, before step S10, the D-SPECT system needs to be controlled to return to the Home position, i.e. the L-type tomographic probe maintains a horizontal position, and the support is vertical to the horizontal plane. Further, the distance between the radiation source simulation nuclide 2 and the central position of the folded angle of the L-shaped tomographic imaging probe 1 of the D-SPECT system can be adjusted by the adjustable clamp, and at this time, the distance between the radiation source simulation nuclide 2 and the central position of the folded angle of the L-shaped tomographic imaging probe 1 is not limited to the distance between the radiation source simulation nuclide 2 and the central position of the folded angle of the L-shaped tomographic imaging probe 1. At this time, before the detection units acquire the scan data of the radionuclide in the first period, the quality control method further includes the following steps:

s01: and adjusting the distance between the radioactive source simulation nuclide and the central position of the folded angle of the L-shaped tomography probe according to the application parameters. Since distances from the L-shaped tomographic imaging probe are different when the patient actually lies on the seat to scan the respective target scan objects such as the heart, the distances can be determined according to the target scan objects in order to ensure accuracy of the D-SPECT system scan data after detection by quality control. The distance may be determined from empirical values, such as a range of 10cm to 20cm for the distance of the radiation source simulating nuclide from the central location at the inflection angle of the distance of the L-shaped tomographic imaging probe when the D-SPECT system is used as a heart-specific SPECT. The adjustment of the relative positions of the radioactive source simulation nuclide 2 and the L-shaped tomographic imaging probe 1 can be realized by using clamps with different lengths, and the technical scheme for realizing the distance adjustment is not limited. After determining the relative distance between the radioactive source simulation nuclide 2 and the L-shaped tomographic imaging probe 1, a customized radioactive source simulation nuclide, such as a Co-57 line source, is only inserted at the other end of the clamp before data scanning.

S20: the plurality of scanning data are divided into a plurality of first sub-data sets corresponding to different time points according to time information, and the first sub-data sets can be regarded as a set of photon information at each position of the radioactive source simulation nuclide acquired by a plurality of detection units at the same time point. And/or each scan data is divided into a second sub-data set corresponding to different positions according to the spatial information, wherein the second sub-data set can be data related to the number of incident photons in the whole first time period acquired by a single detection unit.

S30: and obtaining uniformity and/or resolution of the scanning data according to a plurality of the first sub-data sets, and/or obtaining a plurality of time activity curves according to a plurality of the second sub-data sets, wherein as the radionuclide source is simulated by the radioactive source to attenuate along with time, the number of incident photons in the whole first time period acquired by the single detection unit is also reduced along with time, so as to obtain a time activity curve, and as shown in the lower left graph of fig. 3, the attenuation rate is obtained according to the time activity curve.

In some embodiments, obtaining uniformity of the scan data and/or resolution from the plurality of the first sub-data sets in step S30 may include the steps of:

s31: obtaining a panoramic view of the corresponding time point of the radionuclide for the radiation source simulation according to the first sub-data set of each time point; more specifically, an ordered subset maximum expectation value (OSEM) algorithm may be utilized to reconstruct an image from the number of incident photons acquired by a plurality of detection units at a point in time.

S32: and obtaining the uniformity and/or resolution of the scanning data of the corresponding time points according to the panoramic image of each time point.

S40: the dynamic scan quality of the D-SPECT system is determined from the uniformity of the scan data, the resolution of the scan data, and/or a plurality of the time activity curves.

Since the radionuclide is linear, the panorama obtained should be a cylindrical radiation pattern centered on the radionuclide. Theoretically, photons at the circumference with the distance R from the radionuclide simulated by the radioactive source are uniformly distributed, at this time, uniformity can be judged by dividing a panoramic image with the radius R into units, dividing the number of photons corresponding to each unit into levels, corresponding to different color levels, wherein the higher the color level corresponding to the unit with the larger number of photons is, the brighter the color level is, and evaluating the difference of the color levels of all units to obtain a uniformity index. FIG. 3 is a diagram of radiosource simulated nuclides scan data of a D-SPECT system according to an embodiment of the present application, wherein an L-shaped tomographic imaging probe of the D-SPECT system is provided with nine detection units, and cardiac scan data of each detection unit is represented by a photon map in which the number of photons is displayed as a color level. For example, the number of photons for each cell may be obtained; respectively carrying out difference calculation on the photon quantity of each unit and the reference photon quantity to obtain a plurality of photon quantity difference values; calculating the ratio of each photon quantity difference value to the reference photon quantity to obtain a plurality of ratios; obtaining the number of units with the difference value larger than a preset ratio according to the plurality of ratios, and calculating the number percentage of the units with the difference value larger than the preset ratio to the total number of units of the panorama; the number percentage can be used as a judging parameter of uniformity, when the number percentage is larger than a first threshold value, the uniformity is considered to be poor, at the moment, the resolution index in the dynamic scanning quality of the D-SPECT system is considered to not meet the set requirement, and the D-SPECT system needs to be adjusted to be used for data acquisition of an actual target scanning object. When the number percentage is less than or equal to the first threshold, the uniformity may be considered to meet the set requirement, at which time the dynamic scan quality of the D-SPECT system is considered to meet the set requirement.

Likewise, according to the panorama, a judgment parameter of the resolution may be obtained, and whether the resolution is greater than a second threshold value is judged; if so, the resolution index in the dynamic scanning quality of the D-SPECT system is considered to not meet the set requirement, and the D-SPECT system needs to be adjusted to be used for data acquisition of an actual target scanning object. If not, the resolution is considered to meet the set requirement, and at the moment, the dynamic scanning quality of the D-SPECT system is considered to meet the set requirement.

In addition, according to the multiple attenuation rates of the multiple time activity curves obtained in the step S30, whether the absolute value of the difference value between the attenuation rate of each attenuation rate and the attenuation rate of the radioactive source simulation nuclide is larger than a third threshold value or not can be respectively judged; and if not, the dynamic scanning quality of the D-SPECT system meets the set requirement. The first threshold, the second threshold and the third threshold are all determined according to practical experience values or models.

In actual use, if the above condition or conditions are met, the dynamic scan quality of the D-SPECT system is deemed to not meet the set requirements. Of course, the level of dynamic scan quality of the D-SPECT system can also be determined by comprehensively considering the influence of uniformity, resolution and time activity curve on the dynamic scan quality according to a model or experience so as to determine whether the D-SPECT system needs to be adjusted before being actually applied to a target scan object, so that a better clinical diagnosis result is achieved. The quality control method utilizes the special radioactive source to simulate nuclide for dynamic quality control scanning, the quality control process is simpler and faster, the quality control D-SPECT system has more accurate data acquisition performance, more accurate clinical diagnosis results can be obtained, and the figure 4 is heart scanning data of the D-SPECT system after the dynamic quality control method is adopted, so that the accuracy of patient diagnosis is improved.

The foregoing is a further detailed description of the application in connection with the preferred embodiments, and it is not intended that the application be limited to the specific embodiments described. It will be evident to those skilled in the art that the application is not limited to the details of the foregoing illustrative embodiments, and that the present application may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the application being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. A dynamic quality control method of a D-SPECT system, wherein the D-SPECT system includes an L-type tomographic probe provided with a plurality of detection units, a radioactive source simulation nuclide, an adjustable clamp, and a processing unit;

the quality control method comprises the following steps:

2. The method of dynamic quality control of a D-SPECT system of claim 1 wherein a distance of the radiation source modeling species from a center location at a break angle of the L-shaped tomographic imaging probe is adjustable by the adjustable clamp.

3. The method of dynamic quality control of a D-SPECT system of claim 2 wherein before the plurality of detection units acquire the plurality of scan data for the radiation source simulation species over a first period of time, the method further comprises the steps of:

4. A method of dynamic quality control of a D-SPECT system according to claim 3 wherein the application parameters are determined from a target scan object.

5. The method of claim 2, wherein the distance between the radionuclide and the central location at the inflection angle of the distance between the L-shaped tomographic imaging probe is in the range of 10cm to 20cm.

6. The method of dynamic quality control of a D-SPECT system of claim 1 further comprising, after the step of obtaining a plurality of time activity curves from a plurality of the second sub-data sets:

and obtaining the attenuation rate according to the time activity curve.

7. The method of dynamic quality control of a D-SPECT system of claim 1 wherein the obtaining of the uniformity and/or resolution of the scan data from a plurality of the first sub-data sets includes the steps of:

8. The method of dynamic quality control of a D-SPECT system of claim 6 wherein the determining the dynamic scan quality of the D-SPECT system from the uniformity of the scan data, the resolution of the scan data, and/or a plurality of the time activity curves includes the steps of:

judging whether the uniformity is larger than a first threshold value;

judging whether the resolution is larger than a second threshold value; and/or

9. The method of dynamic quality control of a D-SPECT system of claim 1 wherein the radioactive source of the radioactive source-mimicking nuclear species is Co-57 and the first duration is 390 seconds.