CN116784892B - Automatic synovial biopsy sampling combined device and application method thereof - Google Patents

Automatic synovial biopsy sampling combined device and application method thereof Download PDF

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Publication number
CN116784892B
CN116784892B CN202310572174.4A CN202310572174A CN116784892B CN 116784892 B CN116784892 B CN 116784892B CN 202310572174 A CN202310572174 A CN 202310572174A CN 116784892 B CN116784892 B CN 116784892B
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needle
sampling
hollow
end closed
closed hollow
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CN116784892A (en
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吴锐
邓奕晗
余淑娇
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First Affiliated Hospital of Nanchang University
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First Affiliated Hospital of Nanchang University
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Abstract

The invention relates to the technical field of medical auxiliary instruments, in particular to an automatic synovial biopsy sampling combined device and a use method thereof, and provides the automatic synovial biopsy sampling combined device which is convenient for rapid operation and stable sampling and simultaneously realizes minimally invasive sampling and the use method thereof, wherein the automatic synovial biopsy sampling combined device comprises the following components: the hollow puncture needle is connected with a hollow cutting edge and a pressing rebound mechanism; a puncture needle core; the front end closed hollow sampling needle comprises a negative pressure device communicating handle, a sampling inclined plane groove and a barb. The invention is connected with the negative pressure device through the negative pressure device communicating handle, and is used for carrying out pumping operation on the inside of the front-end closed hollow sampling needle, ensuring that the synovial tissue enters the sampling inclined surface groove under the action of negative pressure, and promoting the front-end closed hollow sampling needle to be rapidly ejected by pressing the rebound mechanism for cooperation use, and cutting the synovial tissue under the action of the barb.

Description

Automatic synovial biopsy sampling combined device and application method thereof
Technical Field
The invention relates to the technical field of medical instruments, in particular to an automatic synovial biopsy sampling combined device and a use method thereof.
Background
The synovium is an inner layer of the joint capsule, is light red, is smooth and flashing, is thin and soft, consists of loose connective tissue, is covered on the connective tissue membrane on the inner surface of the joint capsule, is a main effector organ of various arthritis including rheumatoid arthritis, is less mixed with other components in the synovium tissue obtained by combining a synovium biopsy technology, is beneficial to the purification and operation of primary cell culture, and can be used for researching the cause, pathogenesis, prognosis and curative effect of the arthritis by people.
Synovial tissue is a smooth, tough, soft tissue free between joints and is not easily cut. The patent publication No. CN106377774A discloses a structure of a joint synovial biopsy needle and a use method thereof, wherein a hollow puncture needle, a puncture needle core, a hollow sampling needle and a sampling needle core are arranged, one end of the hollow puncture needle is provided with a hollow cutting edge, the other end of the hollow puncture needle is provided with a handle, and the end part of the handle is provided with a limit groove; a puncture needle core or a hollow sampling needle is arranged in the hollow puncture needle in a matched manner, one end of the puncture needle core is provided with a solid cutting edge, the other end of the puncture needle core is provided with a handle, and the end part of the handle is provided with a limiting block matched with the limiting groove; one end of the hollow sampling needle is a closed ellipsoid, the other end of the hollow sampling needle is provided with a handle, a rectangular groove is formed in the side wall of the hollow sampling needle, which is close to the ellipsoid, one side of the rectangular groove, which is close to the ellipsoid, is provided with a barb, and two sides of the rectangular groove, which are adjacent to the barb, are provided with cutting edges; the sampling needle core is matched with the inner cavity of the hollow sampling needle, and the sampling needle core consists of a core rod and a handle.
The prior art adopts a spiral mode for sampling, is easy to slide due to the low sampling speed, and can not directly and effectively sample the synovial tissue.
Disclosure of Invention
In order to overcome the defects that the existing device cannot sample rapidly and the sampling process is unstable, the invention provides the automatic synovial biopsy sampling combined device which is convenient for rapid operation and stable sampling and can realize minimally invasive sampling.
The technical proposal is as follows: the utility model provides an automatic synovial membrane biopsy sampling composite set, including the cavity pjncture needle, be provided with hollow blade and press rebound mechanism on the cavity pjncture needle, cavity pjncture needle left end is provided with hollow blade, cavity pjncture needle right-hand member is provided with the installation connecting handle, be equipped with on the installation connecting handle on cavity pjncture needle right-hand member and press rebound mechanism, press rebound mechanism is including pressing the pole, the snap ring, first spring, the second spring, the sleeve, rubber piece and spacing inclined plane, cavity pjncture needle right-hand member slidingtype is provided with the pressure pole, press pole bottom is provided with the snap ring, be provided with first spring between pressure pole and the cavity pjncture needle, cavity pjncture needle left portion slidingtype is provided with the sleeve, be provided with the second spring between sleeve and the cavity pjncture needle, the right part is provided with the rubber piece in the cavity pjncture needle, the rubber piece left side is the spacing inclined plane.
The puncture needle also comprises a puncture needle core, the puncture needle core is arranged in the hollow puncture needle cavity in a matched sliding mode, and the end part of the puncture needle core is provided with a solid cutting edge.
The hollow needle comprises a sleeve, a front end closed hollow sampling needle body, a front end needle head, a left needle head part, a right needle head part, a front end closed hollow sampling needle right part, a sampling bevel groove, a barb and a hollow needle head, wherein the front end closed hollow sampling needle body is arranged in the hollow needle body, the front end closed hollow sampling needle body is matched with the hollow needle body, the front end closed hollow sampling needle body is arranged in the hollow needle body, the front end closed hollow needle body is matched with the hollow needle body, the front end closed hollow sampling needle body is provided with a front end closed hollow sampling needle cavity, the front end closed hollow sampling needle cavity is provided with a front end closed hollow needle body, the front end closed hollow sampling needle cavity is provided with a front end opening groove, and the front end closed hollow needle body is provided with a barb.
The hollow puncture needle also comprises a limiting mechanism, wherein the limiting mechanism comprises a contact block, a wedge rod and a third spring, the wedge rod is arranged on the upper portion in the hollow puncture needle in a sliding mode, the contact block is arranged on the left side of the wedge rod, and the third spring is arranged between the contact block and the hollow puncture needle.
The method for using the automatic synovial biopsy sampling combined device comprises the following specific steps:
step 1: the puncture needle core is inserted into the hollow puncture needle, and then the tissue opening is carried out on the sampling part of the patient through the matching of the hollow puncture needle and the puncture needle core;
step 2: then, the puncture needle core is pulled out by medical staff, and the front-end closed hollow sampling needle is inserted into the hollow puncture needle;
step 3: after the front-end closed hollow sampling needle is inserted, the rebound mechanism is pressed to lock and limit the front-end closed hollow sampling needle;
step 4: after the front-end closed hollow sampling needle cannot be pushed, communicating the negative pressure device with the right side interface of the front-end closed hollow sampling needle, maintaining negative pressure suction, pushing the pressing rod downwards to unlock and pop out the front-end closed hollow sampling needle, cutting and sampling through the barb at the left part of the front-end closed hollow sampling needle, and enabling a sample to enter a sampling inclined plane groove;
step 5: and finally, pulling out the front-end closed hollow sampling needle to finish the sampling operation.
Further, the device also comprises a limiting block, and the right part of the front end closed hollow sampling needle is provided with the limiting block.
Further, the solid cutting edge and the hollow cutting edge are consistent in inclination angle and are positioned in the same plane.
Further, the communicating handle of the negative pressure device is of a multi-stage structure.
Further, the left side of the limiting block is of an arc-shaped structure.
The invention has the following advantages: the invention is characterized in that a negative pressure device is connected with a negative pressure device through a negative pressure device communicating handle, and is used for carrying out pumping and pressing work on the inside of a front-end closed hollow sampling needle, so that a synovial tissue is ensured to enter a sampling inclined plane groove under the action of negative pressure, and the front-end closed hollow sampling needle can be promoted to pop out rapidly through the cooperation of a pressing rebound mechanism, and the synovial tissue is cut under the action of a barb;
secondly, the hollow puncture needle and the puncture needle core are matched to carry out minimally invasive opening on the sampling part, so that the damage to a patient is reduced;
thirdly, the pressing rod is locked and fixed through the cooperation between the contact block and the wedge-shaped rod, so that the limiting effect of the pressing rod and the clamping ring on the front-end closed hollow sampling needle is improved, and the stability is enhanced.
Drawings
Fig. 1 is a schematic perspective view of the present invention.
Fig. 2 is a schematic perspective view of the puncture needle core of the present invention.
Fig. 3 is a schematic perspective view of the front-end closed hollow sampling needle and the limiting block of the invention.
FIG. 4 is a cross-sectional view of the front end closed hollow sampling needle and stopper of the present invention.
Fig. 5 is a perspective sectional view of the push rebound mechanism, the limit mechanism and the hollow puncture needle and a perspective schematic view of the front-end closed hollow sampling needle and the limit block.
Fig. 6 is an enlarged view of part a of the present invention.
FIG. 7 is a schematic view of the invention showing the structure of the push-spring mechanism, the limiting mechanism and the hollow puncture needle in cross section and the structure of the front-end-closed hollow sampling needle and the limiting block.
In the above figures: 1: hollow pjncture needle, 2: hollow blade, 3: puncture needle core, 31: solid cutting edge, 4: front-end closed hollow sampling needle, 41: arc blade, 42: negative pressure device communication handle, 43: sampling bevel groove, 44: barb, 5: limiting block, 6: pressing the rebound mechanism, 61: pressing bar, 62: snap ring, 63: first spring, 64: second spring, 65: sleeve, 66: rubber block, 67: limiting inclined plane, 7: limit mechanism, 71: contact block, 72: wedge bar, 73: and a third spring.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
1-7, including cavity pjncture needle 1, be connected with hollow blade 2 and pressing rebound mechanism 6 on the cavity pjncture needle 1, cavity pjncture needle 1 left end is connected with the hollow blade 2 that is used for assisting cutting tissue, cavity pjncture needle 1 right-hand member is connected with the installation joint lever, be equipped with on the installation joint lever on cavity pjncture needle 1 right-hand member and press rebound mechanism 6, it includes pressing rod 61 to press rebound mechanism 6, snap ring 62, first spring 63, second spring 64, sleeve 65, rubber block 66 and spacing inclined plane 67, pressing rod 61 is connected with in the sliding of cavity pjncture needle 1 right-hand member, pressing rod 61 upper portion is passed cavity pjncture needle 1, pressing rod 61 bottom is connected with snap ring 62, be connected with first spring 63 between pressing rod 61 and the cavity pjncture needle 1, cavity pjncture needle 1 left side is connected with sleeve 65, be connected with second spring 64 between sleeve 65 and the cavity pjncture needle 1, the right-hand member is connected with rubber block 66, rubber block 66 left side is spacing inclined plane 67.
The puncture needle comprises a hollow puncture needle 1, and is characterized by further comprising a puncture needle core 3, wherein the inner cavity of the hollow puncture needle 1 is connected with the puncture needle core 3 for assisting in puncture sampling in a matched sliding manner, the end part of the puncture needle core 3 is connected with a solid cutting edge 31, and the solid cutting edge 31 is consistent with the hollow cutting edge 2 in inclination angle and is positioned in the same plane.
The biopsy needle also comprises a front-end closed hollow sampling needle 4, the inner cavity of the hollow puncture needle 1 is connected with the front-end closed hollow sampling needle 4 for performing biopsy sampling in a matched sliding manner, the front-end closed hollow sampling needle 4 is divided into a left needle head part and a right holding part, the right holding part of the front-end closed hollow sampling needle 4 is matched with the diameter of the inner opening of the sleeve 65, the diameter of the right holding part of the front-end closed hollow sampling needle 4 is slightly smaller than the diameter of the inner opening of the sleeve 65, the diameter of the right holding part of the front-end closed hollow sampling needle 4 is larger than the diameter of the left needle head part, the left end of the closed hollow sampling needle 4 of front end is connected with convex blade 41, and convex blade 41 is used for dredging the tissue that has opened, avoids causing secondary injury to patient tissue, and the right-hand member of the closed hollow sampling needle 4 of front end is connected with and is used for the negative pressure ware intercommunication handle 42 that is connected with negative pressure extraction device, and negative pressure ware intercommunication handle 42 is multistage structure, and open on the closed hollow sampling needle 4 of front end left side tip has the sample inclined plane groove 43 that is used for keeping aside the biopsy sample, and the one side that the sample inclined plane groove 43 is close to left side tip is connected with barb 44.
The device further comprises a limiting block 5, the right part of the front end closed hollow sampling needle 4 is connected with the limiting block 5, and the left side of the limiting block 5 is of an arc-shaped structure.
The device further comprises a limiting mechanism 7, wherein the limiting mechanism 7 comprises a contact block 71, a wedge-shaped rod 72 and a third spring 73, the wedge-shaped rod 72 used for clamping and locking the pressing rod 61 is connected to the upper portion in the hollow puncture needle 1 in a sliding mode, the contact block 71 capable of being pushed by the limiting block 5 is connected to the left side of the wedge-shaped rod 72, the third spring 73 is connected between the contact block 71 and the hollow puncture needle 1, and the third spring 73 is wound on the wedge-shaped rod 72.
When the slide film biopsy sampling detection is carried out on a patient, the device can be used for assisting medical staff in sampling the patient, firstly, the puncture needle core 3 is inserted into the hollow puncture needle 1, the hollow cutting edge 2 and the solid cutting edge 31 are positioned on the same horizontal plane, then, puncture treatment is carried out on a sampling part of the patient, a tissue opening is opened, the puncture needle core 3 is pulled out rightward after the completion, the hollow puncture needle 1 is left in the patient, and then, the front-end closed hollow sampling needle 4 is inserted into the hollow puncture needle 1.
It should be specifically noted that, as the front-end closed hollow sampling needle 4 enters the hollow puncture needle 1, in this process, the front-end closed hollow sampling needle 4 drives the stopper 5 to move leftward, so that the left side of the stopper 5 contacts with the rubber block 66, and extrudes the rubber block 66, so that the left part of the front-end closed hollow sampling needle 4 enters the hollow puncture needle 1, and then continues to push the front-end closed hollow sampling needle 4 leftward, so that the left side of the stopper 5 contacts with the right side of the contact block 71, and pushes the contact block 71, so that the contact block 71 drives the wedge rod 72 to slide leftward, the third spring 73 is forced and stretched, and as the wedge rod 72 slides leftward, the pressing rod 61 is not locked and fixed any more at this time, the first spring 63 is in a forced and compressed state in an initial state, and under the action of the first spring 63, the snap ring 62 drives the pressing rod 61 to slide upward, so that the right side of the stopper 5 is fixed and limited by the snap ring 62, so that the stopper 5 drives the front-end closed hollow sampling needle 4 to be locked.
It should be noted that, in the process that the front-end closed hollow sampling needle 4 slides leftwards, the holding part at the right part of the front-end closed hollow sampling needle 4 contacts and pushes the closing part at the left side inside the sleeve 65, so that the sleeve 65 slides leftwards, thereby enabling the second spring 64 to be stressed and compressed, further assisting the front-end closed hollow sampling needle 4 to stably pass through the hollow puncture needle 1, after the front-end closed hollow sampling needle 4 passes through the hollow puncture needle 1, dredging the part of the patient slide film tissue which is opened by the circular arc-shaped cutting edge 41, avoiding tissue opening closure, simultaneously, as the left end part of the circular arc-shaped cutting edge 41 can open the tissue, and as the left end part of the circular arc-shaped cutting edge 41 is of a cambered surface structure, the circular arc-shaped cutting edge 41 can be effectively prevented from causing additional damage to the tissue, the tissue channel which is opened by the puncture needle core 3 in the synovial tissue is opened by the inclined surface structure on the circular arc-shaped cutting edge 41, the front-end closed hollow sampling needle 4 is further assisted to smoothly enter the synovial tissue and sample, the front-end closed hollow sampling needle 4 cannot be pushed continuously, the front-end closed hollow sampling needle 4 is completely positioned, then the front-end closed hollow sampling needle 4 is communicated with a negative pressure device through a negative pressure device at the right end of the front-end closed hollow sampling needle 4 and connected with the negative pressure device, the negative pressure device is started, the inside of the front-end closed hollow sampling needle 4 is kept in a negative pressure state, then the pressing rod 61 is pushed downwards, the clamp ring 62 slides downwards, the first spring 63 is restored to be stressed and compressed, the left side of the clamp ring 62 does not limit and lock the right side of the limiting block 5 any more, the front-end closed hollow sampling needle 4 is unlocked under the action of the second spring 64, the sleeve 65 drives the front end closed hollow sampling needle 4 to slide and pop up rightwards, and simultaneously under the action of the third spring 73, the contact block 71 drives the wedge rod 72 to slide rightwards for resetting, and pushes the front end closed hollow sampling needle 4 in cooperation with the sleeve 65, and at the moment, the wedge rod 72 locks and fixes the pressing rod 61 again.
It should be noted that, in the process that the front end closed hollow sampling needle 4 pops up rightward, the limiting inclined plane 67 on the left side of the rubber block 66 can block and position the front end closed hollow sampling needle 4, so as to avoid the front end closed hollow sampling needle 4 from directly popping up, meanwhile, the barb 44 on the front end closed hollow sampling needle 4 can cut and sample, under the action of negative pressure suction, the biopsy sample enters the sampling inclined plane groove 43 on the left side of the front end closed hollow sampling needle 4, then the negative pressure device is disconnected with the front end closed hollow sampling needle 4, and the front end closed hollow sampling needle 4 is pulled out rightward by force, so as to complete the slide film biopsy sampling.
The application method of the automatic synovial biopsy sampling combined device comprises the following specific steps:
step 1: the puncture needle core 3 is inserted into the hollow puncture needle 1, and then the tissue opening is carried out on the sampling part of the patient through the matching of the hollow puncture needle 1 and the puncture needle core 3;
step 2: then the medical staff pulls out the puncture needle core 3 and inserts the front-end closed hollow sampling needle 4 into the hollow puncture needle 1;
step 3: after the front-end closed hollow sampling needle 4 is inserted, the rebound mechanism 6 is pressed to lock and limit the front-end closed hollow sampling needle 4;
step 4: after the front end closed type hollow sampling needle 4 cannot be pushed, communicating the negative pressure device with the right side interface of the front end closed type hollow sampling needle 4, maintaining negative pressure suction, pushing the pressing rod 61 downwards to unlock and pop out the front end closed type hollow sampling needle 4, cutting and sampling are carried out through the barb 44 at the left part of the front end closed type hollow sampling needle 4, and a sample enters the sampling inclined plane groove 43;
step 5: finally, the front-end closed hollow sampling needle 4 is pulled out to finish the sampling operation.
The embodiments of the present invention have been described in detail with reference to the drawings, but the present invention is not limited to the above embodiments, and various changes can be made within the knowledge of those skilled in the art without departing from the spirit of the present invention.

Claims (5)

1. The utility model provides an automatic synovial membrane biopsy sampling composite set, including cavity pjncture needle (1), be provided with hollow blade (2) on cavity pjncture needle (1) and press rebound mechanism (6), cavity pjncture needle (1) left end is provided with hollow blade (2), and cavity pjncture needle (1) right-hand member is provided with the installation connecting handle, is equipped with on the installation connecting handle on cavity pjncture needle (1) right part and presses rebound mechanism (6), its characterized in that: the pressing rebound mechanism (6) comprises a pressing rod (61), a clamping ring (62), a first spring (63), a second spring (64), a sleeve (65), a rubber block (66) and a limiting inclined surface (67), wherein the pressing rod (61) is arranged on the right part of the hollow puncture needle (1) in a sliding mode, the clamping ring (62) is arranged on the bottom of the pressing rod (61), the first spring (63) is arranged between the pressing rod (61) and the hollow puncture needle (1), the sleeve (65) is arranged on the left part of the hollow puncture needle (1) in a sliding mode, the second spring (64) is arranged between the sleeve (65) and the hollow puncture needle (1), the rubber block (66) is arranged on the right part in the hollow puncture needle (1), and the left side of the rubber block (66) is the limiting inclined surface (67);
the medical puncture needle also comprises a puncture needle core (3), the puncture needle core (3) is arranged in the cavity of the hollow puncture needle (1) in a matched sliding manner, and a solid cutting edge (31) is arranged at the end part of the puncture needle core (3);
the hollow needle comprises a hollow needle body, and is characterized by further comprising a front-end closed hollow sampling needle (4), wherein the inner cavity of the hollow needle body (1) is matched with the sliding type, the front-end closed hollow sampling needle (4) is provided with a front-end closed hollow sampling needle (4), the front-end closed hollow sampling needle (4) is divided into a left needle head part and a right holding part, the right holding part of the front-end closed hollow sampling needle (4) is matched with the diameter of an inner opening of a sleeve (65), the diameter of the right holding part of the front-end closed hollow sampling needle (4) is slightly smaller than the diameter of the inner opening of the sleeve (65), the diameter of the right holding part of the front-end closed hollow sampling needle (4) is larger than the diameter of the left needle head part, the left end of the front-end closed hollow sampling needle (4) is provided with a circular arc cutting edge (41) for dredging the opened tissues, the right end of the front-end closed hollow sampling needle (4) is provided with a negative pressure device communicating handle (42), the left end of the front-end hollow sampling needle (4) is provided with a sampling inclined groove (43), and one side of the inclined surface groove (43) close to the left end is provided with a barb (44);
the device also comprises a limiting mechanism (7), wherein the limiting mechanism (7) comprises a contact block (71), a wedge rod (72) and a third spring (73), the wedge rod (72) is arranged at the upper part in the hollow puncture needle (1) in a sliding manner, the contact block (71) is arranged at the left side of the wedge rod (72), and the third spring (73) is arranged between the contact block (71) and the hollow puncture needle (1);
the method for using the automatic synovial biopsy sampling combined device comprises the following specific steps:
step 1: the puncture needle core (3) is inserted into the hollow puncture needle (1), and then the tissue opening is carried out on the sampling part of the patient through the matching of the hollow puncture needle (1) and the puncture needle core (3);
step 2: then, the puncture needle core (3) is pulled out by medical staff, and the front-end closed hollow sampling needle (4) is inserted into the hollow puncture needle (1);
step 3: after the front-end closed hollow sampling needle (4) is inserted, the rebound mechanism (6) is pressed to lock and limit the front-end closed hollow sampling needle (4);
step 4: after the front-end closed hollow sampling needle (4) cannot be pushed, communicating the negative pressure device with the right side interface of the front-end closed hollow sampling needle (4), keeping negative pressure suction, pushing the pressing rod (61) downwards, unlocking and ejecting the front-end closed hollow sampling needle (4), cutting and sampling through a barb (44) at the left part of the front-end closed hollow sampling needle (4), and enabling a sample to enter a sampling inclined plane groove (43);
step 5: finally, the front-end closed hollow sampling needle (4) is pulled out to finish the sampling operation.
2. The automatic synovial biopsy sampling assembly device according to claim 1, further comprising a limiting block (5), wherein the limiting block (5) is arranged at the right part of the front-end closed hollow sampling needle (4).
3. An automated slide film biopsy sampling assembly according to claim 1, wherein the solid cutting edge (31) is inclined at the same angle as the hollow cutting edge (2) and lies in the same plane.
4. An automated slide film biopsy sampling assembly as claimed in claim 1, wherein the negative pressure vessel communication handle (42) is of a multi-stage construction.
5. An automated slide film biopsy sampling assembly as claimed in claim 2, wherein the left side of the stop block (5) is of arcuate configuration.
CN202310572174.4A 2023-05-22 2023-05-22 Automatic synovial biopsy sampling combined device and application method thereof Active CN116784892B (en)

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