CN116576318B

CN116576318B - Sterile connection device, butt connector, system and connection method

Info

Publication number: CN116576318B
Application number: CN202310861031.5A
Authority: CN
Inventors: 蒋青锋; 王峰; 俞晓琳; 何亚琼
Original assignee: Joymed Technology (suzhou) Ltd
Current assignee: Joymed Technology (suzhou) Ltd
Priority date: 2023-07-14
Filing date: 2023-07-14
Publication date: 2023-09-26
Anticipated expiration: 2043-07-14
Also published as: CN116576318A

Abstract

The invention belongs to the technical field of fluid sterile conveying, and in particular relates to a sterile connecting device, a butt joint device, a system and a connecting method, wherein the sterile connecting device comprises a butt joint component, and a through fluid channel for fluid circulation is arranged in the sterile connecting device; a sealing member disposed inside the fluid passage; a first diaphragm connected to the front surface of the docking member to cover the sealing member; the positive left side of docking member sets up first connecting element, and the right side sets up the second connecting element, and first connecting element is including the first buckle that outwards sets up and inwards set up the second buckle, and first buckle and second buckle crisscross setting. The invention can provide a sterilization passage in a non-bacteria blocking environment, reduce the dependence on the bacteria blocking environment and realize quick and efficient connection. The invention can reduce the variety of the sterile connection device, further reduce the processing equipment, processing technique and the like of the sterile connection device, has simple structure and greatly reduces the processing cost.

Description

Sterile connection device, butt connector, system and connection method

Technical Field

The invention belongs to the technical field of fluid sterile conveying, and particularly relates to a sterile connecting device, a butt joint device, a system and a connecting method.

Background

Fluid is directed from one location to another in a variety of different industries, including biopharmaceutical, biotechnology, food, beverage, cosmetic and pharmaceutical industries, large or small systems of pipes, tubes, hoses and other conduits. The fluid may be a gas, a liquid or a mixture of gases, liquids and/or solids. Some of these fluid systems transfer these fluids from one sterile location to another and have very stringent sterility requirements. Some contaminants, including biological contaminants (e.g., viruses, bacteria, or microorganisms) and environmental contaminants (e.g., grime), are easily introduced into the fluid for a variety of reasons.

The biotechnology industry uses different manufacturing systems between process vessels and equipment, such as sterile connections between fluid bags and pumps. Current connection systems are limited by environmental factors such as clean rooms or tanks to ensure a sterile barrier during connection. However, maintaining a clean room effective is time consuming, difficult and expensive.

The aseptic tube welder can be used to join thermoplastic tubing in an aseptic manner without the need for a cleanroom, laminar flow box or similar environmental control device. After cooling of the thermoplastic tube, a sterile connection is formed. Tube welders are also typically limited in applicability to specific tube sizes and materials, such as thermoplastic tubes. Furthermore, pipe welders are often large, lack versatility, and are expensive.

The prior art aseptic connection devices are formed after butt-jointing using pre-sterilized aseptic connection assemblies, such as one disclosed in prior art CN102405369B, with the first aseptic connection device inserted into the second aseptic connection device; the method includes removing a first septum from a first aseptic coupling device and a second septum from a second aseptic coupling device, and rotating a latch on the first aseptic coupling device to compress a first sealing member of the first aseptic coupling device with a second sealing member of the second aseptic coupling device to form a sterilizing fluid passageway. However, the prior art has a complex structure, high processing cost, complex processing technology and higher cost. Accordingly, there is a need for a fluid aseptic connection device that not only provides a safe sterile barrier, but also provides for efficient and quick connection and low manufacturing costs.

Disclosure of Invention

In order to solve the technical problems of complex structure and high processing cost of an aseptic connecting device in the prior art, the invention provides an aseptic connecting device, a butt joint device, a system and a connecting method.

In order to achieve the above purpose, the technical scheme of the invention is as follows:

an aseptic connection device, comprising:

a docking member having a fluid passage therethrough for fluid communication;

a sealing member disposed inside the fluid passage, and an outer surface of the sealing member protruding from a front surface of the abutting member;

a first diaphragm connected to the front surface of the docking member to cover the sealing member and peelable from the front surface of the docking member;

the left side of the front of the butt joint component is provided with a first connecting component, the right side of the front of the butt joint component is provided with a second connecting component, the first connecting component comprises a first connecting piece which is arranged outwards and a second connecting piece which is arranged inwards, and the first connecting piece and the second connecting piece are arranged in a staggered mode.

The first connecting piece is a first buckle, and the second connecting piece is a second buckle.

Further, after the aseptic connecting device rotates 180 degrees, the first connecting component and the second connecting component on the same side can be mutually embedded to form a clamping structure.

Further, the second connecting member comprises a first locking hook arranged far away from the abutting member and a second locking hook arranged close to the abutting member; a certain distance is reserved between the first lock hook and the second lock hook, and an empty groove for the first connecting component to be inserted is formed; the first lock hooks and the second lock hooks are arranged in a staggered manner;

the first lock hook is arranged corresponding to the first buckle in position, and the second lock hook is arranged corresponding to the second buckle in position.

Still further, first connecting member includes a plurality of connecting rods and sets up in the first buckle or the second buckle of connecting rod tip, the connecting rod is L type, and connecting rod one end is connected in the butt joint member, and the other end of connecting rod sets up first buckle or second buckle.

Further, the second connecting member comprises a first connecting bracket far away from the butt joint member and a second connecting bracket close to the butt joint member, two ends of the first connecting bracket are connected to the butt joint member, a first lock hook is arranged on the inner wall of the first connecting bracket, and a first elastic sheet is arranged between the adjacent first lock hooks; the two ends of the second connecting support are connected to the butt joint members, the second lock hooks are arranged above the second connecting support, and a second elastic piece is arranged on two sides of each second lock hook.

Further, the first elastic sheet comprises a first base body and a first fastening head arranged above the first base body, the lower end of the first base body is connected to the first connecting bracket, and the rest surfaces of the first base body and the surface of the first fastening head are not contacted with the first connecting bracket;

the second elastic sheet comprises a second base body and a second fastening head arranged above the second base body, the lower end of the second base body is connected to the second connecting bracket, and the rest surfaces of the second base body and the surfaces of the second fastening head are not contacted with the second connecting bracket.

Furthermore, a guide groove is arranged on the front surface of the abutting component close to the first connecting component, a guide block is arranged on the front surface of the abutting component close to the second connecting component, the guide block and the guide groove can be mutually embedded, and the guide block and the guide groove are correspondingly arranged.

Further, the first connecting member is identical in structure to the second connecting member.

Further, the number of the first buckles is 3, and the number of the second buckles is 2.

Further, two protrusions are diagonally provided on the front surface of the docking member.

Further, the fluid channel is a step hole, the aperture of the fluid channel close to the front face of the abutting component is larger than the aperture of the fluid channel far away from the front face of the abutting component, and the sealing component is arranged in the step hole of the fluid channel close to the front face of the abutting component.

Further, the sealing member is a sealing ring, an annular outer groove is formed in the outer surface of the sealing ring, and an annular inner groove is formed in the inner surface of the sealing ring; the outer groove and the inner groove are arc-shaped, and the radius of the outer groove and the radius of the arc are smaller than that of the inner groove.

Further, the first diaphragm includes a tab and a film, one end of which is circular for completely covering the sealing member; the other end of the film is connected with the pull ring; the outer surface of the pull ring is provided with a third buckle and a groove, and after the first diaphragm rotates 180 degrees, the third buckle can be inserted into the groove.

Further, the aseptic connection device further includes a protective cover covering the docking member front face for protecting the first membrane; the upper side of visor sets up movable hook, the downside of visor sets up fixed hook, movable hook with the equal joint of fixed hook is in the butt joint component to the outside of movable hook sets up the spanner, pulls the spanner and can break away from movable hook in the butt joint component.

Further, a tower head is arranged on the back surface of the butt joint component, and the tower head is a single-section tower head or a multi-section tower head.

The invention also provides an aseptic butt joint device, which comprises a first aseptic connecting device and a second aseptic connecting device, wherein fluid channels are arranged in the first aseptic connecting device and the second aseptic connecting device, and an aseptic circulating channel for fluid to flow is formed after the first aseptic connecting device is in butt joint with the second aseptic connecting device; wherein, the aseptic connecting device is adopted to the aseptic connecting device of above-mentioned aseptic connecting device of first aseptic connecting device and second aseptic connecting device.

The invention also provides an aseptic butt joint device, which comprises a first aseptic connecting device and a second aseptic connecting device, wherein fluid channels are arranged in the first aseptic connecting device and the second aseptic connecting device, and an aseptic circulating channel for fluid to flow is formed after the first aseptic connecting device is in butt joint with the second aseptic connecting device; wherein the first sterile connection device adopts the sterile connection device; the second sterile connection device comprises a butt joint component, a sealing component and a first diaphragm, wherein a through fluid channel for fluid circulation is arranged in the butt joint component; the sealing member is arranged in the fluid channel, and the outer surface of the sealing member protrudes out of the front surface of the abutting member; the first diaphragm is connected to the front face of the abutting member to cover the sealing member and is peelable from the front face of the abutting member; a third connecting member is arranged on the left side of the front surface of the abutting member, and a fourth connecting member is arranged on the right side of the front surface of the abutting member;

the third connecting member and the fourth connecting member have the same structure, the first connecting member is inserted into the third connecting member to form a clamping structure, and the second connecting member is inserted into the fourth connecting member to form a clamping structure.

The invention also provides a sterile connection system which comprises a first container, a second container and a sterile connector for communicating the first container and the second container, wherein the sterile connector is adopted.

The invention also provides a sterile connection method, which adopts the sterile connection device and comprises the following steps:

s1, providing two sterile connecting devices which have the same structure and are respectively covered with a protective cover and a first diaphragm;

s2, removing the protective cover, and exposing the front surfaces of the two sterile connecting devices respectively covering the first diaphragm;

s3, butting the front surfaces of the two sterile connecting devices, overlapping pull rings of the two first diaphragms, and butting fluid channels of the two sterile connecting devices;

s4, removing the first diaphragm to form an aseptic channel, and realizing aseptic connection of the fluid channel.

Compared with the prior art, the invention has the following beneficial effects:

by arranging the first diaphragm, the sterile connection device is prevented from being polluted, a sterilization passage can be provided for two or more fluids in a non-bacterial blocking environment, dependence on the bacterial blocking environment is reduced, and connection is rapid and efficient.

According to the invention, the connecting members which are mutually embedded are arranged on the two butt joint members, so that the establishment of a sterile passage can be realized only by one sterile connecting device, the types of the sterile connecting devices are reduced, and further, the processing equipment, the processing technology and the like of the sterile connecting devices are reduced, so that the structure is simple, and the processing cost is greatly reduced.

Drawings

Fig. 1 is a schematic structural diagram of a first embodiment of the present invention.

Fig. 2 is an exploded view of the first embodiment of the present invention.

Fig. 3 is a schematic structural view of a docking member according to a first embodiment of the present invention.

Fig. 4 is a schematic structural view of the docking member according to another embodiment of the present invention.

Fig. 5 is a top view of the docking member according to the first embodiment of the present invention.

Fig. 6 is a schematic structural diagram of a seal ring according to a first embodiment of the invention.

Fig. 7 is a schematic structural diagram of a protective cover according to a first embodiment of the invention.

Fig. 8 is a schematic structural diagram of a docking member in a second embodiment of the present invention.

Fig. 9 is a schematic structural diagram of the third embodiment of the present invention before docking.

Fig. 10 is a schematic structural diagram of a third embodiment of the present invention without removing the film.

Fig. 11 is a schematic diagram of a structure after removing a thin film according to a third embodiment of the present invention.

Fig. 12 is a schematic structural view of a docking member of the second aseptic connection device in the fourth embodiment of the present invention.

Fig. 13 is a block diagram of a fifth embodiment of the present invention.

Reference numerals illustrate:

1-docking member, 101-first connecting member, 1101-first clasp, 1102-second clasp, 1103-connecting rod, 102-second connecting member, 1201-first latch hook, 1202-second latch hook, 1203-first connecting bracket, 1204-second connecting bracket, 1205-first spring, 1206-second spring, 103-guide slot, 104-guide block, 105-bump, 106-pagoda head, 2-sealing ring, 3-first membrane, 301-film, 302-pull ring, 3201-third clasp, 3202-groove, 4-protective cover, 401-movable clasp, 402-fixed clasp, 403-ring, 404-side cover, 5-fluid channel, 6-third connecting member, 7-fourth connecting member, 8-first container, 9-second container, 10-sterile docker.

Detailed Description

The technical solutions of the present invention will be clearly described below with reference to the accompanying drawings, and it is obvious that the described embodiments are not all embodiments of the present invention, and all other embodiments obtained by a person skilled in the art without making any inventive effort are within the scope of protection of the present invention.

Description of custom words:

front face: indicating that the sterile connection device is in close proximity to the surface of another sterile connection device when in sterile connection. And the terms "left", "right", "upper" and "lower" are used in the present invention to describe structural features in conjunction with the drawings, and do not limit the scope of the present invention.

Example 1

The present invention provides a sterile connection device, as shown in figures 1 and 2, comprising:

a butt joint member 1, wherein a fluid channel 5 for fluid circulation is arranged in the butt joint member 1;

a sealing member which is provided inside the fluid passage 5, and whose outer surface protrudes from the front surface of the abutting member 1;

a first diaphragm 3, the first diaphragm 3 being attached to the front surface of the docking member 1 to cover the sealing member and being peelable from the front surface of the docking member 1;

the left side of the front surface of the docking member 1 is provided with a first connecting member 101, as shown in fig. 3, the right side of the front surface of the docking member 1 is provided with a second connecting member 102, the first connecting member 101 comprises three first buckles 1101 arranged outwards and two second buckles 1102 arranged inwards, and the first buckles 1101 and the second buckles 1102 are staggered.

When the aseptic connection device is rotated 180 °, the first connection member 101 and the second connection member 102 on the same side can be mutually engaged to form a clamping structure. Wherein, as shown in fig. 5, the second connecting member 102 includes a first latch hook 1201 disposed away from the docking member 1, and a second latch hook 1202 disposed near the docking member 1; a certain distance is formed between the first latch hook 1201 and the second latch hook 1202, forming a hollow for the first connection member 101 to be inserted; the first latch hooks 1201 and the second latch hooks 1202 are staggered; the first latch hook 1201 is disposed corresponding to the position of the first buckle 1101, and the second latch hook 1202 is disposed corresponding to the position of the second buckle 1102. Accordingly, the number of the first locking hooks 1201 is the same as the number of the first buckles 1101, and the number of the second locking hooks 1202 is the same as the number of the second buckles 1102, and the number is two.

The first connecting member 101 comprises a plurality of connecting rods 1103 and first buckles 1101 or second buckles 1102 arranged at the ends of the connecting rods 1103, the connecting rods 1103 are L-shaped, one ends of the connecting rods 1103 are connected to the butt joint member 1, and the first buckles 1101 or the second buckles 1102 are arranged at the other ends of the connecting rods 1103, so that the first buckles 1101 and the second buckles 1102 can have certain elastic deformation capacity relative to the butt joint member 1.

As shown in fig. 4, the second connecting member 102 includes a first connecting bracket 1203 disposed away from the docking member 1, a second connecting bracket 1204 disposed close to the docking member 1, both ends of the first connecting bracket 1203 being connected to the docking member 1, a first latch hook 1201 being disposed on an inner wall of the first connecting bracket 1203, the first latch hook 1201 being non-deformable with respect to the first connecting bracket 1203; a first elastic piece 1205 is arranged between the adjacent first lock hooks 1201; two ends of the second connecting bracket 1204 are connected to the docking member 1, a second locking hook 1202 is disposed above the second connecting bracket 1204, the second locking hook 1202 cannot deform relative to the second connecting bracket 1204, and two sides of each second locking hook 1202 are provided with a second elastic sheet 1206.

The first elastic piece 1205 comprises a first base body and a first fastening head arranged above the first base body, the lower end of the first base body is connected to the first connecting support 1203, and the rest surfaces of the first base body and the surface of the first fastening head are in non-contact with the first connecting support 1203, so that the first elastic piece 1205 can elastically deform relative to the first connecting support 1203; the second elastic sheet 1206 comprises a second base body and a second fastening head arranged above the second base body, the lower end of the second base body is connected to the second connecting bracket 1204, and the rest surfaces of the second base body and the surfaces of the second fastening head are not contacted with the second connecting bracket 1204, so that the second elastic sheet 1206 can elastically deform relative to the second connecting bracket 1204.

A guide groove 103 is arranged on the front surface of the abutting member 1 close to the first connecting member 101, a guide block 104 is arranged on the front surface of the abutting member 1 close to the second connecting member 102, the guide block 104 and the guide groove 103 can be mutually embedded, the guide groove 103 and the guide block 104 are correspondingly arranged, and the guide groove 103 and the guide block 104 provide a guide function for the connection of the sterile connecting device. Two lugs 105 are diagonally arranged on the front surface of the butt joint member 1, and when two aseptic connecting devices are connected, the lugs 105 can provide protection for the aseptic connecting devices when the aseptic connecting devices are subjected to side loads, and sealing leakage caused by extrusion deformation of the sealing members is avoided.

The fluid channel 5 is a step hole, the aperture of the fluid channel 5 near the front surface of the abutting component 1 is larger than the aperture far away from the front surface of the abutting component 5, the sealing component is arranged in the step hole of the fluid channel 5 near the front surface of the abutting component 1, the outer surface of the sealing component protrudes out of the front surface of the abutting component 1, and when two sterile connecting devices are connected, the sealing component is extruded to provide good sealing.

The sealing member is a sealing ring 2, as shown in fig. 6, an annular outer groove is formed on the outer surface of the sealing ring 2, and an annular inner groove is formed on the inner surface of the sealing ring 2; the outer groove and the inner groove are arc-shaped, the radius of the outer groove and the radius of the arc are smaller than the radius of the arc of the inner groove, and when the sealing ring 2 is compressed, the groove can provide deformation space for longitudinal deformation of the sealing ring, so that the influence on the flow of the fluid passage is avoided. In other embodiments, the sealing member may also be a lip flare-shaped seal ring or an annular cylindrical band-shaped seal ring.

As shown in fig. 2 and 9, the first diaphragm 3 includes a pull ring 302 and a film 301, one end of the film 301 is circular, and a sealing member is completely covered by using a hot-melt welding manner, and a hot-melt welding position is located at the periphery of the sealing member; the other end of the film 301 is connected with a pull ring 302; the outer surface of the pull ring 302 is provided with a third buckle 3201 and a groove 3202, and after the first diaphragm 3 rotates 180 degrees, the third buckle 3201 can be inserted into the groove 3202.

The sterile connection device further comprises a protective cover 4, wherein the protective cover 4 covers the front surface of the abutting member 1 for protecting the first diaphragm 3; as shown in fig. 7, a movable hook 401 is disposed on the upper side of the protective cover 4, a fixed hook 402 is disposed on the lower side of the protective cover 4, the movable hook 401 and the fixed hook 402 are both clamped to the docking member 1, and a wrench is disposed on the outer side of the movable hook 401, and the movable hook 401 can be separated from the docking member 1 by pulling the wrench. The middle part of the protective cover 4 is provided with the circular ring 403, and the circular ring 403 is correspondingly arranged with the sealing ring 2, so that the sealing ring 2 is prevented from shaking and moving, and the film 301 is prevented from being damaged; the underside of the protective cover 4 is provided with a side cover 404 outside the fixing hook 402, and when the protective cover 4 is mounted to the aseptic connecting device, the side cover 404 can cover the rest of the film, so that the film 301 is prevented from being damaged or broken.

The back of the docking member 1 is provided with a pagoda head 106, as shown in fig. 3, the pagoda head 106 is a single-section pagoda head or a multi-section pagoda head. In other embodiments, the pagoda head 106 may be connected to the hose in other forms, such as a TC structure fitting.

Example two

The present embodiment is different from the first embodiment in that: in this embodiment, the first connecting member and the second connecting member have the same structure. As shown in fig. 8, the first connecting member and the second connecting member each adopt the structure of the first connecting member in the first embodiment, and the first connecting member and the second connecting member are symmetrically arranged. A guide groove is provided on the front face of the docking member adjacent to the first connection member, and a guide groove is also provided on the front face of the docking member adjacent to the second connection member. Bumps (not shown) are diagonally provided on the front surface of the docking member. The other structures adopt the corresponding structures in the first embodiment.

Example III

The invention also provides an aseptic butt joint device, which comprises a first aseptic connecting device and a second aseptic connecting device, wherein fluid channels are arranged in the first aseptic connecting device and the second aseptic connecting device, and an aseptic circulating channel for fluid to flow is formed after the first aseptic connecting device is in butt joint with the second aseptic connecting device; wherein, the aseptic connecting device in the first embodiment is adopted by the aseptic connecting device in the first embodiment.

Fig. 9 is a schematic diagram of the structure of the two aseptic connecting devices before connecting, the two aseptic connecting devices are identical in structure but have 180 ° different directions, so that the first connecting member 101 of the aseptic connecting device on the left side corresponds to the second connecting member 102 of the aseptic connecting device on the right side in the figure, and the second connecting member 102 of the aseptic connecting device on the left side corresponds to the first connecting member 101 of the aseptic connecting device on the right side; the guide groove 103 of the aseptic connecting device on the left corresponds to the guide block 104 of the aseptic connecting device on the right, and the guide block 104 of the aseptic connecting device on the left corresponds to the guide groove 103 of the aseptic connecting device on the right. The two aseptic connection devices are then docked as shown in fig. 10 such that the first connection member 101 of the aseptic connection device on the left is inserted into the second connection member 102 of the aseptic connection device on the right to form a snap-in structure, and the first connection member 101 of the aseptic connection device on the right is inserted into the second connection member 102 of the aseptic connection device on the left to form a snap-in structure. Since the first buckle 1101 needs to be elastically deformed during insertion, the aseptic connection device is subjected to a certain lateral force, and the lateral deflection of the aseptic connection device is limited by the guide groove 103 and the guide block 104 structure, so that a guiding effect is provided for docking. At this time, the first diaphragm 3 is not peeled off, and the two seal rings 2 are pressed against each other to form a seal. The pull rings 302 of the two first diaphragms 3 are overlapped, and the third buckle 3201 on the pull ring 302 is inserted into the groove 3202 of the other first diaphragm 3, so that in the process of peeling the first diaphragms 3, the two first diaphragms 3 are peeled at the same time, and the invasion of external bacteria caused by the fact that the sealing ring 2 contacts with the outer surface of the film 301 is avoided.

Figure 11 shows the sterile adaptor after peeling off the first septum 3, the internal fluid channels 5 communicating to form a sterile delivery channel for fluid delivery.

The first connecting member 101 of one aseptic connecting device is inserted into the second connecting member 102 of the other aseptic connecting device, the first buckle 1101 is clamped into the first lock hook 1201 under the action of self elastic deformation, namely, the outer side of the first buckle 1101 is the first lock hook 1201, the inner side of the first buckle 1101 is the second elastic piece 1206, and the second elastic piece 1206 can be elastically deformed, so that the insertion of the first buckle is not influenced, but after the first buckle is successfully inserted, the second elastic piece can play a certain limiting and extruding role on the first buckle 1101 under the action of self elastic deformation, the unhooking of the first buckle 1101 is avoided, and the connection of an aseptic connector is enhanced. Similarly, the second buckle 1102 is clamped into the second lock hook 1202 under the action of self elastic deformation, namely the inner side of the second buckle 1102 is the second lock hook 1202, the outer side of the second buckle 1102 is the first elastic sheet 1205, and the insertion of the second buckle 1102 is not affected because the first elastic sheet 1205 can elastically deform, when the second buckle 1102 is successfully inserted, the first elastic sheet 1205 can play a certain limiting and extrusion role on the second buckle 1102 under the action of self elastic deformation, the unhooking of the second buckle 1102 is avoided, the connection of the sterile connector is further enhanced, and the sterile connector which is safe and reliable and has good sealing performance is provided.

Example IV

The invention also provides an aseptic butt joint device, which comprises a first aseptic connecting device and a second aseptic connecting device, wherein fluid channels are arranged in the first aseptic connecting device and the second aseptic connecting device, and an aseptic circulating channel for fluid to flow is formed after the first aseptic connecting device is in butt joint with the second aseptic connecting device; wherein the first sterile connection device adopts the sterile connection device of the second embodiment; the second sterile connection device comprises a butt joint member, a sealing member and a first diaphragm, wherein a fluid channel which is communicated and used for fluid circulation is arranged in the butt joint member as shown in fig. 12; the sealing member is arranged in the fluid channel, and the outer surface of the sealing member protrudes out of the front surface of the abutting member; the first diaphragm is connected to the front face of the abutting member to cover the sealing member and is peelable from the front face of the abutting member; a third connecting member 6 is arranged on the left side of the front surface of the abutting member, and a fourth connecting member 7 is arranged on the right side of the front surface of the abutting member;

the third connecting member 6 and the fourth connecting member 7 have the same structure, and the third connecting member 6 and the fourth connecting member 7 have the same structure as the second connecting member of the first embodiment. The first connecting member is inserted into the third connecting member 6 to form a clamping structure, and the second connecting member is inserted into the fourth connecting member 7 to form a clamping structure. The other structures of the second sterile connection device in this embodiment, including the sealing member, the fluid passage, the protective cover, and the first septum all adopt the same structure as the corresponding structure of the first embodiment.

Example five

The present invention also provides a sterile connection system, as shown in fig. 13, comprising a first container 8, a second container 9, and a sterile docker 10 communicating the first container 8 and the second container 9, wherein the sterile docker 10 is the sterile docker of the third embodiment or the fourth embodiment.

Example six

The invention also provides a sterile connection method, which adopts the sterile connection device in the first embodiment and comprises the following steps:

s2, removing the protective cover 4 to expose the front surfaces of the two sterile connecting devices respectively covering the first diaphragm 3;

s3, abutting the front surfaces of the two sterile connecting devices, overlapping pull rings 302 of the two first diaphragms 3, and abutting the fluid channels 5 of the two sterile connecting devices;

s4, removing the first diaphragm 3, holding the connector which is already connected by one hand through two-hand operation, and pulling the film pull ring by the other hand to finish film stripping and removing; and forming a sterile channel to realize sterile connection of the fluid channels.

The above embodiments are only for illustrating the technical solution of the present invention and not for limiting the same, and although the present invention has been described in detail with reference to examples, it should be understood by those skilled in the art that modifications and equivalents may be made thereto without departing from the scope of the technical solution of the present invention, which is intended to be covered by the claims of the present invention.

Claims

1. An aseptic connection device, comprising:

a docking member having a fluid passage therethrough for fluid communication;

the device is characterized in that a first connecting component is arranged on the left side of the front surface of the abutting component, a second connecting component is arranged on the right side of the front surface of the abutting component, the first connecting component comprises a first connecting piece which is arranged outwards and a second connecting piece which is arranged inwards, and the first connecting piece and the second connecting piece are arranged in a staggered mode;

the second connecting component comprises a first connecting bracket far away from the butt joint component and a second connecting bracket close to the butt joint component, two ends of the first connecting bracket are connected to the butt joint component, a first lock hook is arranged on the inner wall of the first connecting bracket, and a first elastic sheet is arranged between the adjacent first lock hooks; the two ends of the second connecting support are connected to the butt joint members, the second lock hooks are arranged above the second connecting support, and a second elastic piece is arranged on two sides of each second lock hook.

2. The aseptic connection device of claim 1, wherein the first connector is a first clasp and the second connector is a second clasp.

3. A sterile connection device according to claim 2 wherein the first and second connection members on the same side are capable of interengagement to form a snap-fit arrangement when the sterile connection device is rotated 180 °.

4. A sterile connection device according to claim 3 wherein the second connection member comprises a first latch hook disposed distally from the docking member, a second latch hook disposed proximally from the docking member; a certain distance is reserved between the first lock hook and the second lock hook, and an empty groove for the first connecting component to be inserted is formed; the first lock hooks and the second lock hooks are arranged in a staggered manner;

5. The sterile connection device according to claim 1, wherein the first spring comprises a first base and a first fastening head disposed above the first base, the lower end of the first base being connected to the first connection bracket, the remaining surface of the first base and the surface of the first fastening head being free of contact with the first connection bracket;

6. The aseptic connection device according to claim 4, wherein a guide groove is provided on the front face of the docking member adjacent to the first connection member, a guide block is provided on the front face of the docking member adjacent to the second connection member, and the guide block and the guide groove are capable of being fitted to each other and are provided correspondingly.

7. A sterile connection device according to claim 1 wherein two lugs are diagonally disposed on the front face of the docking member.

8. The aseptic connection device of claim 1, wherein the sealing member is a sealing ring, an outer surface of the sealing ring being provided with an annular outer groove, an inner surface of the sealing ring being provided with an annular inner groove; the outer groove and the inner groove are arc-shaped, and the radius of the outer groove and the radius of the arc are smaller than that of the inner groove.

9. The aseptic connection device of claim 1, wherein the first membrane comprises a tab and a membrane, one end of the membrane being circular for completely covering the sealing member; the other end of the film is connected with the pull ring; the outer surface of the pull ring is provided with a third buckle and a groove, and after the first diaphragm rotates 180 degrees, the third buckle can be inserted into the groove.

10. The aseptic connection device of claim 1, further comprising a protective cover covering the docking member front face for protecting the first membrane; the upper side of visor sets up movable hook, the downside of visor sets up fixed hook, movable hook with the equal joint of fixed hook is in the butt joint component to the outside of movable hook sets up the spanner, pulls the spanner and can break away from movable hook in the butt joint component.

11. The aseptic connection device of claim 1, wherein the first connection member is identical in structure to the second connection member.

12. The sterile connector comprises a first sterile connecting device and a second sterile connecting device, wherein fluid channels are formed in the first sterile connecting device and the second sterile connecting device, and the first sterile connecting device and the second sterile connecting device form a sterile circulation channel for fluid to flow after being connected in a butting manner; characterized in that the aseptic connection device according to any one of claims 1-10 is used for both the first aseptic connection device and the second aseptic connection device.

13. The sterile connector comprises a first sterile connecting device and a second sterile connecting device, wherein fluid channels are formed in the first sterile connecting device and the second sterile connecting device, and the first sterile connecting device and the second sterile connecting device form a sterile circulation channel for fluid to flow after being connected in a butting manner; characterized in that the aseptic connection device of claim 11 is employed as the first aseptic connection device;

the second sterile connection device comprises a butt joint component, a sealing component and a first diaphragm, wherein a through fluid channel for fluid circulation is arranged in the butt joint component; the sealing member is arranged in the fluid channel, and the outer surface of the sealing member protrudes out of the front surface of the abutting member; the first diaphragm is connected to the front face of the abutting member to cover the sealing member and is peelable from the front face of the abutting member; a third connecting member is arranged on the left side of the front surface of the abutting member, and a fourth connecting member is arranged on the right side of the front surface of the abutting member;

14. A sterile connection system comprising a first container, a second container, a sterile docker communicating the first container and the second container, wherein the sterile docker employs the sterile docker of claim 12.

15. A sterile connection method applied to the sterile connection device according to any one of claims 1 to 10, comprising: