CN116370848B - Positioning method and system for radiotherapy - Google Patents
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Abstract
The application relates to a positioning method and a positioning system for radiotherapy, wherein a treatment planning system acquires a planned treatment machine coordinate system, and patient surface contour information in the planned treatment machine coordinate system is acquired based on CT images; acquiring an image in a treatment room and a camera coordinate system based on an AR device, and calculating to acquire a machine room treatment machine coordinate system and a patient body surface reference image under the machine room treatment machine coordinate system; registering the two coordinate systems, and calculating a patient body surface reference image under a camera coordinate system in a treatment room scene; and comparing and displaying the patient body surface reference images under the machine room therapeutic machine coordinate system and the camera coordinate system, and positioning by an operator with the virtual image as a reference. The multi-angle visualization of the planning image under the coordinates of the therapeutic machine is realized by using the augmented reality technology, the problems that an operator repeatedly enters and exits in a machine room, a patient receives additional radiation, the observation angle is limited and the like under the CBCT guiding technology are solved, and the convenience and the accuracy of positioning are improved.
Description
Technical Field
The application relates to the technical field of radiotherapy confirmation, in particular to a positioning method and a positioning system for radiotherapy.
Background
In tumor radiotherapy, a radiotherapy plan is precisely designed according to the patient's position and the tumor's position at the time of positioning. In radiotherapy, X-rays are required to be used for irradiating a tumor part for multiple times, and during treatment, a doctor places the tumor center of a patient into the treatment center of radiotherapy equipment according to the tumor center coordinates in planning, and a link of repeating positioning positions is called positioning. Accurate positioning is one of the key links for ensuring curative effect.
The existing positioning mode is as follows: marking lines on the body surface of a patient according to three orthogonal laser lines during positioning; three orthogonal laser lines are also arranged in the treatment machine room during positioning, and the planned position is reproduced by placing the patient at the position where the laser lines coincide with the body surface mark lines. After the images are placed, the images acquired in the treatment process and the planned images are registered through the imaging devices of the treatment machine room, such as orthogonal digital images, cone beam CT and the like, so that the accuracy of target area positioning is ensured. Further adjustments and confirmation of the planning and treatment images are typically performed manually by an operator after automatic registration. If the registration result indicates that a large positioning error exists, an operator is required to enter the machine room again to repeat the positioning process until the positioning error meets the treatment requirement.
Optical surface tracking is a technique for assisting positioning, and a camera is used for acquiring scattered light of a patient body surface and reconstructing the scattered light by a computer to form a surface profile image. Due to the use of laser or visible light, the body surface contours during positioning and swaying can be compared under the condition of no radiation and real-time operation. However, the conventional optical surface tracking technology has a camera arranged at a fixed position, and can only detect a specific partial body surface area (generally, chest), and cannot be changed according to the visual angle of an operator. In addition, the device does not have display equipment, and the alarm device only can prompt that the positioning error is large, and can not feed back specific problems (such as large arm bending degree difference and the like) to an operator.
Thus, the prior art radiotherapy positioning method has the following defects:
1. under the prior art, an operator firstly operates in a treatment machine room according to body surface marks and laser line mark positions, and then images are acquired in an operation room and registered with a planning image. When the patient position has a large error and can not be corrected through the small-range movement of the treatment bed, an operator needs to enter the machine room again to perform positioning, and the operation is repeated until the error meets the treatment requirement. The process is complicated and the time consumption is long;
2. at present, the monitoring means for the body position change mainly comprises Cone Beam CT (CBCT) scanning and X-ray scanning imaging mode, so that extra radiation can be caused to a patient in the process of repeatedly adjusting the position, and the risk of secondary tumor occurrence of the patient is increased;
3. since only three sets of images of the cross-section, sagittal plane and coronal position can be observed in the current registration, it is difficult for the operator to make a full assessment and adjustment of the minor rotations and movements. Particularly, when the patient has long treatment course, the weight change, the joint curvature change and other conditions possibly occur, and the patient is difficult to accurately position only by the two-dimensional images in three directions.
Therefore, it is necessary to develop a radiotherapy positioning method, which can control positioning errors, reduce the radiation dose born by doctors and patients while time-consuming positioning, and provide real-time feedback to operators.
The foregoing background knowledge is intended to assist those of ordinary skill in the art in understanding the prior art that is closer to the present application and to facilitate an understanding of the inventive concepts and aspects, and it should be understood that the foregoing background art should not be used to assess the novelty of the inventive concepts that lie in the absence of explicit evidence that such disclosure is already disclosed at the time of filing of this patent application.
Disclosure of Invention
In order to solve at least one technical problem mentioned in the background art, the application aims to adopt an augmented reality technology to assist in the positioning process, realize multi-angle visualization of a planning image under the coordinates of a therapeutic machine by using the augmented reality technology, solve the problems that an operator repeatedly enters and exits in a machine room, a patient receives additional radiation, the observation angle is limited and the like under the CBCT guiding technology, and improve the convenience and the accuracy of positioning.
A method of positioning for radiation therapy, comprising:
s100, acquiring a planned therapeutic machine coordinate system by a therapeutic planning system, and acquiring patient surface profile information in the planned therapeutic machine coordinate system based on a patient positioning scanning CT image;
s200, acquiring an image in a treatment room and a camera coordinate system based on an AR device, and calculating to acquire a machine room treatment machine coordinate system and a patient body surface reference image under the camera coordinate system;
s300, registering and overlapping the machine room therapeutic machine coordinate system and the planning therapeutic machine coordinate system, and calculating to obtain a patient body surface reference image under a camera coordinate system in a therapeutic room scene;
s400, comparing and displaying the body surface reference images of the patient obtained in the steps S200 and S300, and positioning by an operator with the virtual image as a reference.
Positioning system for radiotherapy, comprising a 3D vision module and a control terminal which are in communication connection, wherein
The 3D vision module is configured to scan a treatment room scene and is used for acquiring three-dimensional data of the treatment room scene;
the control end is configured to acquire three-dimensional data of the treatment room scene according to the treatment room scene acquisition data and realize the positioning method of the radiotherapy.
Further, the 3D vision module includes an AR device.
A computer readable storage medium having stored therein a computer program executable by a processor, the computer program when executed by the processor implementing at least one step of the positioning method of radiation therapy described above.
An electronic device comprising a processor and a memory having stored thereon a computer program which, when executed by the processor, performs at least one step of the positioning method of radiation therapy described above.
The beneficial effects of the application are as follows:
the application has the advantages that an operator can see the virtual positioning body position of the patient in the treatment machine room, compared with the traditional laser line contrast positioning or the traditional optical body surface tracking mode, the reference object is more visual, the positioning is more convenient, the reference range is wider, the body position of the patient can be finely adjusted in various directions at multiple angles, and meanwhile, the radiation treatment efficiency and accuracy are obviously improved; the positioning guide mode of the virtual image is non-radiative, so that the complicated process that an operator repeatedly enters and exits the machine room is avoided, and the radiation dose suffered by doctors and patients is reduced.
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To make the above and/or other objects, features, advantages and examples of the present application more comprehensible, the accompanying drawings which are needed in the detailed description of the present application are simply illustrative of the present application and other drawings can be obtained without inventive effort for those skilled in the art.
FIG. 1 is a block flow diagram of a positioning method for radiation therapy;
fig. 2 is a technical roadmap of a positioning method of radiation therapy.
Detailed Description
Suitable substitutions and/or modifications of the process parameters will be apparent to those skilled in the art from the disclosure herein, however, it is to be expressly pointed out that all such substitutions and/or modifications are intended to be encompassed by the present application. While the products and methods of preparation of the present application have been described in terms of preferred embodiments, it will be apparent to those skilled in the relevant art that variations and modifications can be made in the products and methods of preparation described herein without departing from the spirit and scope of the application.
Unless defined otherwise, technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The present application uses the methods and materials described herein; other suitable methods and materials known in the art may be used. The materials, methods, and examples described herein are illustrative only and not intended to be limiting. All publications, patent applications, patents, provisional applications, database entries, and other references mentioned herein, and the like, are incorporated herein by reference in their entirety. In case of conflict, the present specification, including definitions, will control.
Unless specifically stated otherwise, the materials, methods, and examples described herein are illustrative only and not intended to be limiting. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present application, suitable methods and materials are described herein.
In order to facilitate an understanding of the embodiments of the present application, abbreviations and key terms that may be involved in the embodiments of the present application are first explained or defined.
The present application is described in detail below.
A method of positioning for radiation therapy, comprising:
s100, acquiring a planned therapeutic machine coordinate system by a therapeutic planning system, and acquiring patient surface profile information in the planned therapeutic machine coordinate system based on a patient positioning scanning CT image;
s200, acquiring an image in a treatment room and a camera coordinate system based on an AR device, and calculating to acquire a machine room treatment machine coordinate system and a patient body surface reference image under the camera coordinate system;
s300, registering and overlapping the machine room therapeutic machine coordinate system and the planning therapeutic machine coordinate system, and calculating to obtain a patient body surface reference image under a camera coordinate system in a therapeutic room scene;
s400, comparing and displaying the body surface reference images of the patient obtained in the steps S200 and S300, and positioning by an operator with the virtual image as a reference.
As a preferred aspect of the present application, in step S100, the step of acquiring, by the treatment planning system, the planned treatment machine coordinate system specifically includes the following steps: analyzing the positioning CT into matrix form, taking the center point of the treatment plan as coordinate point (0, 0), determining the coordinate system of the plan treatment machine by using the direction attribute in DICOM format used by CT, and recording as XYZ 1 。
As a preferred aspect of the present application, in step S100, the acquiring patient surface contour information in the coordinate system of the planning therapeutic machine based on the patient positioning scan CT image specifically performs the following steps: coordinate system XYZ of planning therapeutic machine 1 And (3) delineating the surface profile information of the patient in the patient positioning scanning CT image, and marking as C1.
As the optimization of the technical scheme of the application, the sketching method adopts one of manual sketching, automatic threshold segmentation and deep learning segmentation methods.
As a preferred embodiment of the present application, in step S200, the AR device includes a camera and a display device, and the relative positions of the camera and the display device remain unchanged.
As a preferred aspect of the present application, the display device is removable, including a hand-held tablet or AR glasses.
As a preference to the solution of the application, a laser light device is arranged in the treatment room, which is configured to identify the mechanical centre point and the coordinate system of the radiotherapy device in the treatment.
As a preferable mode of the technical scheme of the application, the laser lamp device comprises 3-4 laser lamps.
As an optimization of the technical scheme of the present application, in step S200, the steps of obtaining the image and the camera coordinate system in the treatment room based on the AR device, obtaining the machine room treatment machine coordinate system and the patient body surface reference image under the camera coordinate system by calculation are specifically performed as follows:
shooting at the current position by a camera, and identifying a laser lamp line after shooting;
after identification, defining the intersection point of the laser lamp lines as the origin (0, 0) of coordinates in the world coordinate system, and calculating the current camera coordinate system XY according to the intersection angle of the laser lamp lines 3 Coordinate system XYZ of therapeutic machine in machine room 2 Matrix of transformation relations M between 1 So that XYZ 2 ×M 1 =XY 3 The method comprises the steps of carrying out a first treatment on the surface of the Further obtain camera coordinate system XY according to laser lamp indication 3 Lower patient body surface reference image S 2 。
As a preferable mode of the technical scheme of the present application, in step S300, the machine room therapeutic machine coordinate system XYZ is set 2 Coordinate system XYZ of planning therapeutic machine 1 Registering to obtain a transformation relation matrix M 2 The matrix M 2 So that XYZ 1 ×M 2 =XYZ 2 。
As a preferred embodiment of the present application, in step S300, the calculating obtains a patient body surface reference image under a camera coordinate system in a treatment room scene, and the following steps are performed:
coordinate system XYZ of the planning therapeutic machine 1 Lower patient surface profile information C 1 According to the transformation relation matrix M 2 Transforming to obtain coordinate system XYZ of therapeutic machine in machine room 2 Underlying planning surface profile matrix C 1 '，C 1 '=C 1 ×M 2 ；
Matrix C the planning surface profile 1 Coordinate system XYZ of machine room therapeutic machine 2 Three-dimensional data in (a) is converted into a camera coordinate system XY 3 Reference image S of the body surface of the patient 1 ，S 1 =C 1 '×M 1 。
As a preferred embodiment of the present application, step S400 specifically includes: will S 1 And S is 2 Meanwhile, the position is displayed in the display device, and an operator finely adjusts the posture and the position of the patient according to the scene displayed by the display device to finish positioning.
The application provides a positioning method for radiotherapy, the whole conception is that the augmented reality technology is applied to radiotherapy positioning, a mobile AR device is adopted, positioning body surface data are acquired at any angle and displayed simultaneously with planned body surface data under the angle, an operator can see the virtual positioning body position of a patient in a treatment machine room through the scheme of the application, compared with the traditional laser line contrast positioning or the traditional optical body surface tracking mode, a reference object is more visual, the positioning is more convenient, the reference range is wider, and the body position of the patient can be finely adjusted in various directions at multiple angles; in addition, the positioning guide mode of the virtual image is non-radiative, so that the complicated process that an operator repeatedly enters and exits the machine room is avoided, and the radiation dose suffered by a doctor and a patient is reduced.
Positioning system for radiotherapy, comprising a 3D vision module and a control terminal which are in communication connection, wherein
The 3D vision module is configured to scan a treatment room scene and is used for acquiring three-dimensional data of the treatment room scene;
the control end is configured to acquire three-dimensional data of the treatment room scene according to the treatment room scene acquisition data and realize the positioning method of the radiotherapy.
As a preference to the technical solution of the present application, the 3D vision module includes an AR device.
As the optimization of the technical scheme of the application, the AR device comprises an optical camera for scanning the scene of the treatment room so as to acquire laser lines at different angles and acquire a machine room treatment machine coordinate system.
Example 1:
an augmented reality-based radiotherapy positioning method has a flow chart shown in fig. 1, a technical route shown in fig. 2, and specifically comprises the following steps.
Step 1, extracting a coordinate system XYZ of a planning therapeutic machine from a positioning CT of a patient in a radiotherapy planning system 1 Patient surface profile information C in the coordinate system 1 ；
Step 1-1, analyzing the positioning CT into a matrix form, taking the center point of the treatment plan as a coordinate point (0, 0), and determining the coordinate system XYZ of the planning treatment machine by using the direction attribute in the DICOM format used by the CT 1 ；
Step 1-2, delineating the surface contour of the patient in CT, wherein the delineating method can be implemented in various ways, in this example, manual delineation is adopted to obtain the coordinate system XYZ of the planning therapeutic machine 1 Lower patient surface profile information C 1 。
Step 2, arranging an AR device in a treatment machine room, wherein the AR device comprises a camera and a display device; wherein the display device is movable, including a hand-held tablet or AR glasses, the relative positions of the camera and the display device remaining fixed.
And 3, arranging a set of laser lamp device in the treatment machine room, wherein the set of laser lamp device consists of 4 laser lamps, and the laser lamp group is used for marking the mechanical center point and the coordinate system of the radiotherapy equipment in the treatment machine room. The device is generally standard in radiotherapy, and is not inventive.
Step 4, acquiring treatment of the machine room by a camera in the AR device according to the indication of the laser lampCoordinate system XYZ 2 Camera coordinate system XY 3 Lower patient body surface reference image S 2 ；
Step 4-1, shooting at the current position by a camera, and identifying a laser lamp line by adopting a threshold segmentation method after shooting;
step 4-2, after identification, defining the intersection point of the laser lamp lines as an original point (0, 0) in the world coordinate system; calculating the current camera coordinate system XY according to the intersection angle of the laser lamp lines 3 Coordinate system XYZ of therapeutic machine in machine room 2 Matrix of transformation relations M between 1 So that XYZ 2 ×M 1 =XY 3 。
Step 5, coordinate system XYZ of the machine room therapeutic machine in step 4 2 And the planning machine coordinate system XYZ described in step 1 1 Registering to obtain a transformation relation matrix M 2 The matrix is such that XYZ 1 ×M 2 =XYZ 2 。
Step 6, coordinate system XYZ of the planning therapeutic machine in the step 1 1 Lower patient surface profile information C 1 According to the transformation relation matrix M in step 5 2 Transforming to obtain coordinate system XYZ of therapeutic machine in machine room 2 Underlying planning surface profile matrix C 1 '，C 1 '=C 1 ×M 2 ；
Step 7, the planning surface profile matrix C1' in the step 6 is formed by a planning therapeutic machine coordinate system XYZ 1 Three-dimensional data in (a) is converted into a camera coordinate system XY 3 Reference image S of the body surface of the patient 1 ，S 1 =C 1 '×M 1 。
And 8, displaying the S1 and the S2 in the display device of the AR device in the step 2 at the same time.
And 9, the operator finely adjusts the posture and the position of the patient according to the scene displayed in the step 8, and positioning is completed.
According to the scheme, a patient CT is acquired through a radiotherapy planning system, a planning therapeutic machine coordinate system and a patient surface contour under the coordinate system are extracted, then the machine room therapeutic machine coordinate system and a patient surface reference image under the coordinate system are acquired through an AR device arranged in a therapeutic machine room, the machine room therapeutic machine coordinate system and the planning therapeutic machine coordinate system are registered to obtain a transformation relation matrix, inverse transformation is carried out on patient contour information under the planning therapeutic machine coordinate system by using the transformation relation matrix to obtain a planning surface contour matrix, then the patient surface reference image in a camera coordinate system is obtained according to the transformation relation matrix between a camera coordinate system and the machine room therapeutic machine coordinate system, finally the patient surface reference image under the machine room therapeutic machine coordinate system and the patient surface reference image in the camera coordinate system are displayed in a display device of the AR device, and an operator can finish positioning according to a displayed scene. In the scheme of the application, an operator can see the virtual positioning position of the patient in the treatment machine room, so that compared with a traditional positioning mode, the method has the advantages of more visual reference object, more convenient positioning, wider reference range and the like, can finely adjust the position of the patient in all directions at multiple angles, remarkably improves the convenience and accuracy of positioning, can reduce the radiation dose suffered by doctors and patients, and has larger popularization value.
Example 2:
on the basis of the foregoing embodiments, a positioning system for radiation therapy based on augmented reality is provided, which includes a 3D vision module and a control end that are in communication connection, wherein the 3D vision module includes a plurality of optical cameras for scanning a scene of a treatment room, so as to collect laser lines at different angles, so as to obtain a machine room treatment machine coordinate system; the control end is configured to acquire three-dimensional data of the treatment room scene according to the treatment room scene acquisition data and realize the radiotherapy positioning method based on augmented reality.
Example 3:
on the basis of the foregoing embodiments, a computer readable storage medium is provided, in which a computer program executable by a processor is stored, where the computer program, when executed by the processor, implements at least one step of the positioning method based on augmented reality radiotherapy described in the foregoing embodiments, and can achieve the same technical effect, and for avoiding repetition, a description is omitted herein.
Example 4:
on the basis of the foregoing embodiments, an electronic device is provided, which includes a processor and a memory, where the memory stores a computer program, where the computer program implements at least one step of the positioning method based on augmented reality radiotherapy described in the foregoing embodiments when executed by the processor, and the steps can achieve the same technical effects, so that repetition is avoided, and details are not repeated here.
Computer-readable media include both permanent and non-permanent, removable and non-removable media, and information storage may be implemented by any method or technology. The information may be computer readable instructions, data structures, modules of a program, or other data. Examples of storage media for a computer include, but are not limited to, phase change memory (PR AM), static Random Access Memory (SRAM), dynamic Random Access Memory (DRAM), other types of Random Access Memory (RAM), read Only Memory (ROM), electrically Erasable Programmable Read Only Memory (EEPROM), flash memory or other memory technology, compact disc read only memory (CD-ROM), digital Versatile Disks (DVD) or other optical storage, magnetic cassettes, magnetic tape magnetic disk storage or other magnetic storage devices, or any other non-transmission medium, which can be used to store information that can be accessed by a computing device. Computer-readable media, as defined herein, does not include transitory computer-readable media (transmission media), such as modulated data signals and carrier waves.
The conventional technology in the above embodiments is known to those skilled in the art, and thus is not described in detail herein.
The specific embodiments described herein are offered by way of example only to illustrate the spirit of the application. Various modifications or additions to the described embodiments may be made by those skilled in the art to which the application pertains or may be substituted in a similar manner without departing from the spirit of the application or beyond the scope of the appended claims.
While the application has been described in detail and with reference to specific embodiments thereof, it will be apparent to one skilled in the art that various changes and modifications can be made therein without departing from the spirit and scope thereof.
While the above detailed description has shown, described, and pointed out novel features as applied to various embodiments, it will be understood that various omissions, substitutions, and changes in the form and details of the device or method illustrated may be made without departing from the spirit of the disclosure. In addition, the various features and methods described above may be used independently of one another, or may be combined in various ways. All possible combinations and subcombinations are intended to fall within the scope of this disclosure. Many of the embodiments described above include similar components, and thus, these similar components are interchangeable in different embodiments. While the application has been disclosed in the context of certain embodiments and examples, it will be understood by those skilled in the art that the application extends beyond the specifically disclosed embodiments to other alternative embodiments and/or uses and obvious modifications and equivalents thereof. Therefore, the present application is not intended to be limited by the specific disclosure of the preferred embodiments herein.
The application is a well-known technique.
Claims (7)
1. A method of positioning for radiation therapy, comprising:
s100, acquiring a planned therapeutic machine coordinate system by a therapeutic planning system, and acquiring patient surface profile information in the planned therapeutic machine coordinate system based on a patient positioning scanning CT image;
s200, acquiring an image in a treatment room and a camera coordinate system based on an AR device, and calculating to acquire a machine room treatment machine coordinate system and a patient body surface reference image under the camera coordinate system;
s300, registering and overlapping the machine room therapeutic machine coordinate system and the planning therapeutic machine coordinate system, and calculating to obtain a patient body surface reference image under a camera coordinate system in a therapeutic room scene;
s400, comparing and displaying the patient body surface reference images under the camera coordinate system obtained in the steps S200 and S300, and positioning by an operator with the virtual image as a reference;
step S100The step of acquiring the planned therapeutic machine coordinate system by the therapeutic planning system specifically comprises the following steps: analyzing the positioning CT into matrix form, taking the center point of the treatment plan as coordinate point (0, 0), determining the coordinate system of the plan treatment machine by using the direction attribute in DICOM format used by CT, and recording as XYZ 1 ；
In step S100, the acquiring patient surface contour information in the coordinate system of the planning therapeutic machine based on the patient positioning scan CT image specifically performs the following steps: coordinate system XYZ of planning therapeutic machine 1 The contour information of the patient surface in the CT image is marked as C 1 ；
In step S200, the steps of obtaining the image and the camera coordinate system in the treatment room based on the AR device, calculating and obtaining the machine room treatment machine coordinate system and the patient body surface reference image under the camera coordinate system are specifically performed as follows:
shooting at the current position by a camera, and identifying a laser lamp line after shooting;
after identification, defining the intersection point of the laser lamp lines as the origin (0, 0) of coordinates in the world coordinate system, and calculating the current camera coordinate system XY according to the intersection angle of the laser lamp lines 3 Coordinate system XYZ of therapeutic machine in machine room 2 Matrix of transformation relations M between 1 So that XYZ 2 ×M 1 =XY 3 The method comprises the steps of carrying out a first treatment on the surface of the Further obtain camera coordinate system XY according to laser lamp indication 3 Lower patient body surface reference image S 2 。
2. The positioning method of radiation therapy according to claim 1, wherein:
in step S300, the machine room treatment machine coordinate system XYZ 2 Coordinate system XYZ of planning therapeutic machine 1 Registering to obtain a transformation relation matrix M 2 The matrix M 2 So that XYZ 1 ×M 2 =XYZ 2 。
3. The positioning method of radiation therapy according to claim 1, wherein:
in the step S300, the calculating obtains a patient body surface reference image under a camera coordinate system in the treatment room scene, and performs the following steps:
coordinate system XYZ of the planning therapeutic machine 1 Lower patient surface profile information C 1 According to the transformation relation matrix M 2 Transforming to obtain coordinate system XYZ of therapeutic machine in machine room 2 Underlying planning surface profile matrix C 1 '，C 1 '=C 1 ×M 2 ；
The planning surface profile matrix C1' is formed by a machine room therapeutic machine coordinate system XYZ 2 Three-dimensional data in (a) is converted into a camera coordinate system XY 3 Reference image S of the body surface of the patient 1 ，S 1 =C 1 '×M 1 。
4. A positioning system for radiation therapy, characterized in that:
3D vision module and control terminal comprising communication connection, wherein
The 3D vision module is configured to scan a treatment room scene and is used for acquiring three-dimensional data of the treatment room scene;
the control terminal is configured to acquire three-dimensional data of the treatment room scene according to the collection data of the treatment room scene and realize the positioning method of the radiation treatment according to any one of claims 1-3.
5. The positioning system for radiation therapy of claim 4, wherein: the 3D vision module includes an AR device.
6. A computer-readable storage medium having stored thereon a computer program executable by a processor, characterized in that: the computer program, when executed by a processor, implements at least one step of the positioning method of radiation therapy according to any one of claims 1-3.
7. An electronic device comprising a processor and a memory, the memory having a computer program stored thereon, characterized in that: the computer program, when executed by the processor, implements at least one step of the positioning method of radiation therapy of any one of claims 1-3.
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| CN202310953431.9A CN117797415A (en) | 2023-06-07 | 2023-06-07 | Positioning method and positioning system for tumor radiotherapy |
| CN202310664564.4A CN116370848B (en) | 2023-06-07 | 2023-06-07 | Positioning method and system for radiotherapy |
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Citations (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1583194A (en) * | 2003-08-24 | 2005-02-23 | 中国科学院等离子体物理研究所 | Method and system for high accurate positioning for radiotherapy |
| WO2007028237A1 (en) * | 2005-09-06 | 2007-03-15 | Resonant Medical Inc. | System and method for patient setup for radiotherapy treatment |
| CN101952837A (en) * | 2008-01-15 | 2011-01-19 | 艾可瑞公司 | The use of the single radioscopic image of the three-dimensional imaging centering of the quality assurance that is used to follow the tracks of |
| CN104755136A (en) * | 2012-10-12 | 2015-07-01 | 维申Rt有限公司 | Patient monitor |
| CN106880906A (en) * | 2017-03-15 | 2017-06-23 | 中国科学院近代物理研究所 | A kind of real-time verification device and method that position is put for patient in radiotherapy |
| CN109568811A (en) * | 2018-11-29 | 2019-04-05 | 太丛信息科技（上海）有限公司 | A method of the radiotherapy group establishment of coordinate system based on body surface optical imagery |
| CN110237441A (en) * | 2019-05-30 | 2019-09-17 | 新乡市中心医院(新乡中原医院管理中心) | Coordinate method positions in radiotherapy and puts the application of position |
| WO2021012149A1 (en) * | 2019-07-22 | 2021-01-28 | 北京市肿瘤防治研究所 | Method and system for monitoring radiotherapy emitted beam |
| CN113599718A (en) * | 2021-06-15 | 2021-11-05 | 苏州普能医疗科技有限公司 | Radiotherapy positioner based on diagnostic image |
| CN114177544A (en) * | 2022-01-17 | 2022-03-15 | 中国科学院合肥物质科学研究院 | CT and optical co-positioning auxiliary device for radiotherapy planning |
| WO2022136925A1 (en) * | 2020-12-23 | 2022-06-30 | Ebamed Sa | A multiplanar motion management system |
| WO2022141150A1 (en) * | 2020-12-30 | 2022-07-07 | 西安大医集团股份有限公司 | Position adjustment method, head-mounted display device and radiotherapy system |
| CN114913385A (en) * | 2022-06-29 | 2022-08-16 | 浙江省肿瘤医院 | Multi-modal image data analysis method and system |
| CN115006737A (en) * | 2022-02-16 | 2022-09-06 | 常州市第二人民医院 | Radiotherapy body position monitoring system based on depth camera |
| WO2022198553A1 (en) * | 2021-03-25 | 2022-09-29 | 中国科学院近代物理研究所 | Three-dimensional image-guided positioning method and system, and storage medium |
| CN115137998A (en) * | 2022-08-02 | 2022-10-04 | 南京工业职业技术大学 | Automatic patient positioning system and method for radiotherapy |
| CN115227987A (en) * | 2022-07-26 | 2022-10-25 | 西安一体医疗科技有限公司 | Method and device for detecting positions of patient and radiotherapy equipment |
| WO2022251417A1 (en) * | 2021-05-26 | 2022-12-01 | The Brigham And Women's Hospital, Inc. | System and methods for patient tracking during radiaton therapy |
| CN115702983A (en) * | 2021-08-09 | 2023-02-17 | 西安大医集团股份有限公司 | Positioning control method, device, system and medium for radiotherapy equipment |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7860550B2 (en) * | 2004-04-06 | 2010-12-28 | Accuray, Inc. | Patient positioning assembly |
| US7623623B2 (en) * | 2007-06-29 | 2009-11-24 | Accuray Incorporated | Non-collocated imaging and treatment in image-guided radiation treatment systems |
| US20090082660A1 (en) * | 2007-09-20 | 2009-03-26 | Norbert Rahn | Clinical workflow for treatment of atrial fibrulation by ablation using 3d visualization of pulmonary vein antrum in 2d fluoroscopic images |
| US8088055B2 (en) * | 2010-05-24 | 2012-01-03 | Mitsubishi Electric Research Laboratories, Inc. | Plan-based medical image registration for radiotherapy |
| WO2016206743A1 (en) * | 2015-06-25 | 2016-12-29 | Brainlab Ag | Utilization of a transportable ct-scanner for radiotherapy procedures |
| US11273326B2 (en) * | 2017-06-29 | 2022-03-15 | Canon Medical Systems Corporation | Radiotherapy system and treatment support apparatus |
| CN115869551A (en) * | 2021-09-26 | 2023-03-31 | 西安大医集团股份有限公司 | Positioning method, processing device, radiotherapy system and storage medium |
-
2023
- 2023-06-07 CN CN202310953431.9A patent/CN117797415A/en active Pending
- 2023-06-07 CN CN202310664564.4A patent/CN116370848B/en active Active
Patent Citations (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1583194A (en) * | 2003-08-24 | 2005-02-23 | 中国科学院等离子体物理研究所 | Method and system for high accurate positioning for radiotherapy |
| WO2007028237A1 (en) * | 2005-09-06 | 2007-03-15 | Resonant Medical Inc. | System and method for patient setup for radiotherapy treatment |
| CN101952837A (en) * | 2008-01-15 | 2011-01-19 | 艾可瑞公司 | The use of the single radioscopic image of the three-dimensional imaging centering of the quality assurance that is used to follow the tracks of |
| CN104755136A (en) * | 2012-10-12 | 2015-07-01 | 维申Rt有限公司 | Patient monitor |
| CN106880906A (en) * | 2017-03-15 | 2017-06-23 | 中国科学院近代物理研究所 | A kind of real-time verification device and method that position is put for patient in radiotherapy |
| CN109568811A (en) * | 2018-11-29 | 2019-04-05 | 太丛信息科技（上海）有限公司 | A method of the radiotherapy group establishment of coordinate system based on body surface optical imagery |
| CN110237441A (en) * | 2019-05-30 | 2019-09-17 | 新乡市中心医院(新乡中原医院管理中心) | Coordinate method positions in radiotherapy and puts the application of position |
| WO2021012149A1 (en) * | 2019-07-22 | 2021-01-28 | 北京市肿瘤防治研究所 | Method and system for monitoring radiotherapy emitted beam |
| WO2022136925A1 (en) * | 2020-12-23 | 2022-06-30 | Ebamed Sa | A multiplanar motion management system |
| WO2022141150A1 (en) * | 2020-12-30 | 2022-07-07 | 西安大医集团股份有限公司 | Position adjustment method, head-mounted display device and radiotherapy system |
| WO2022198553A1 (en) * | 2021-03-25 | 2022-09-29 | 中国科学院近代物理研究所 | Three-dimensional image-guided positioning method and system, and storage medium |
| WO2022251417A1 (en) * | 2021-05-26 | 2022-12-01 | The Brigham And Women's Hospital, Inc. | System and methods for patient tracking during radiaton therapy |
| CN113599718A (en) * | 2021-06-15 | 2021-11-05 | 苏州普能医疗科技有限公司 | Radiotherapy positioner based on diagnostic image |
| CN115702983A (en) * | 2021-08-09 | 2023-02-17 | 西安大医集团股份有限公司 | Positioning control method, device, system and medium for radiotherapy equipment |
| CN114177544A (en) * | 2022-01-17 | 2022-03-15 | 中国科学院合肥物质科学研究院 | CT and optical co-positioning auxiliary device for radiotherapy planning |
| CN115006737A (en) * | 2022-02-16 | 2022-09-06 | 常州市第二人民医院 | Radiotherapy body position monitoring system based on depth camera |
| CN114913385A (en) * | 2022-06-29 | 2022-08-16 | 浙江省肿瘤医院 | Multi-modal image data analysis method and system |
| CN115227987A (en) * | 2022-07-26 | 2022-10-25 | 西安一体医疗科技有限公司 | Method and device for detecting positions of patient and radiotherapy equipment |
| CN115137998A (en) * | 2022-08-02 | 2022-10-04 | 南京工业职业技术大学 | Automatic patient positioning system and method for radiotherapy |
Non-Patent Citations (1)
| Title |
|---|
| 影像引导在放疗摆位中的误差分析;魏胜涛;;世界最新医学信息文摘(48);正文全文 * |
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